The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-2)

April 18, 2019 updated by: Pfizer

Phase 3 Multi Center, Double Blind, Randomized, Placebo Controlled, Parallel Group Evaluation Of The Efficacy, Safety, And Tolerability Of Bococizumab (Pf-04950615), In Reducing The Occurrence Of Major Cardiovascular Events In High Risk Subjects

This study evaluates the PCSK9 inhibitor, Bococizumab (PF-04950615;RN316), compared to placebo, in reducing the occurrrence of major cardiovascular events, including cardiovascular death, myocardial infarction, stroke, and unstable angina requiring urgent revascularization in high risk subjects who are receiving background lipid lowering therapy and have cholesterol laboratory values of LDL-C >/= 100 mg/dL (2.6 mmol/L) or non-HDL-C >/=130 mg/dL (3.4 mmol/L).

Study Overview

Status

Terminated

Conditions

Cardiovascular Disease

Intervention / Treatment

Detailed Description

The trial was terminated prematurely on November 1, 2016, due to the emerging clinical profile and the evolving treatment and market landscape for lipid-lowering agents. These indicated that bococizumab was not likely to provide value to patients, physicians, or shareholders. The decision was not based on a recommendation by the independent Data Monitoring Committee to stop the program.

Study Type

Interventional

Enrollment (Actual)

10564

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Argentina
- - Ciudad Autonoma De B. Aires, Argentina, C1405BUB
    - Cicemo - Consultorio de Investigaciones Clinicas E.M.O. S.R.L.
  - Ciudad Autonoma De Buenos Aires, Argentina, C1405BCK
    - Universidad Maimonides
  - Ciudad Autonoma de B. Aires, Argentina, C1428ART
    - Instituto Cardiovascular de Buenos Aires
  - Ciudad Autonoma de Buenos Aires, Argentina, C1430CKE
    - Centro de Investigacion: AXISMED S.R.L.
  - Cordoba, Argentina, X5003DCE
    - Instituto Médico DAMIC S.R.L.
  - Cordoba, Argentina, X5000BNB
    - ILAIM Instituto Latinoamericano de Investigaciones Medicas
  - Cordoba, Argentina, X5000EPU
    - Clinico Chutro SRL
  - Cordoba, Argentina, X5000EVQ
    - Centro de Investigaciones Clinicas "Instituto del Corazon"
  - Cordoba, Argentina, x5002AOQ
    - Clínica Privada Colombo
  - Cordoba, Argentina, X5006IKK
    - Centro Medico Luquez
  - Cordoba, Argentina, X5008KKF
    - Ipac Caraffa
  - Corrientes, Argentina, 3400
    - Instituto de Cardiologia de Corrientes "Juana Fca. Cabral"
  - Mendoza, Argentina, 5500
    - Hospital Central de Mendoza
  - Salta, Argentina, 4400
    - Cordis S.A.
  - Salta, Argentina, A4406BPF
    - Centro Cardiovascular Salta
  - San Luis, Argentina, D5702JRS
    - Instituto Cardiovascular San Luis A.E.
- Buenos Aires
  - Bahia Blanca, Buenos Aires, Argentina, B8001HXM
    - Hospital Italiano Regional Del Sur
  - Bahia Blanca, Buenos Aires, Argentina, B8000FTD
    - Instituto de Investigaciones Clinicas Bahia Blanca
  - C.a.b.a., Buenos Aires, Argentina, C1119ACN
    - CIPREC - Centro de Investigacion y Prevencion Cardiovascular S.A.
  - Ciudad Autonoma de B. Aires, Buenos Aires, Argentina, C1280AEB
    - Hospital Britanico de Buenos Aires
  - Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, C1425DES
    - CEDIC - Consultorios Medicos
  - Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, C1179AAB
    - Investigaciones Medicas IMOBA S.R.L.
  - Coronel Suarez, Buenos Aires, Argentina, B7540GHD
    - Clinica Coronel Suarez S.A.
  - La Plata, Buenos Aires, Argentina, B1902COS
    - Framingham Centro Médico
  - Lanus Este, Buenos Aires, Argentina, B1824KAJ
    - CIMeL CHAHIN CHAHIN S.A.
  - Mar del Plata, Buenos Aires, Argentina, B7600FZN
    - Instituto de Investigaciones Clinicas Mar del Plata
  - Ramos Mejia, Buenos Aires, Argentina, B1704ETD
    - Dim Clinica Privada
  - Zarate, Buenos Aires, Argentina, B2800DGH
    - Instituto de Investigaciones Clinicas Zarate
- C.a.b.a.
  - C.a.b.a, C.a.b.a., Argentina, C1425AGC
    - Consultorios Asociados de Endocrinología e Investigación Clínica Aplicada
- Caba
  - C.a.b.a, Caba, Argentina, C1023AAB
    - Stat Research S.A.
- Cordoba
  - Villa Maria, Cordoba, Argentina, 5901
    - Clinica Privada de Especialidades Medicas
- Mendoza
  - Godoy Cruz, Mendoza, Argentina, M5501ARP
    - CIPADI Centro Integral de Prevencion y Atencion en Diabetes
- PCIA DE Buenos Aires
  - Ciudadela, PCIA DE Buenos Aires, Argentina, 1702
    - IMEP Instituto Medico Elsa Perez
  - Moron, PCIA DE Buenos Aires, Argentina, B1708CGU
    - Instituto Medico Aguero
- PCIA DE Chaco
  - Resistencia, PCIA DE Chaco, Argentina, H3500CDM
    - Cordis - Instituto del Corazon
- PCIA DE Formosa
  - Formosa, PCIA DE Formosa, Argentina, 3600
    - Hospital de Alta Complejidad "Pte. Juan Domingo Perón"
- PCIA DE Santa FE
  - Santa Fe, PCIA DE Santa FE, Argentina, S3000EOZ
    - Hospital Provincial Dr. José Maria Cullen
  - Santa Fe, PCIA DE Santa FE, Argentina, S3000FWO
    - Centro de Investigaciones Clinicas del Litoral S.R.L.
  - Santa Fe, PCIA DE Santa FE, Argentina, S3004CVS
    - Cedir S.A - Centro De Diagnostico Y Rehabilitacion S.A.
- PCIA DE Tucuman
  - San Miguel De Tucuman, PCIA DE Tucuman, Argentina, T4000IFL
    - Centro Modelo de Cardiologia
- Pcia. DE Santa FE
  - Rosario, Pcia. DE Santa FE, Argentina, S2000CFK
    - Instituto de Hematologia y Medicina Clinica "Dr. Ruben A. Davoli"
- Provincia DE Santa FE
  - Rosario, Provincia DE Santa FE, Argentina, S2000QID
    - Instituto Medico Ceniclar - Central De Investigaciones Clinicas Argentina - Sanatorio De La Mujer
- Tucuman
  - San Miguel de Tucuman, Tucuman, Argentina, T4000IAF
    - Centro Medico CCBR Tucuman
Australia
- New South Wales
  - Camperdown, New South Wales, Australia, 2050
    - Royal Prince Alfred Hospital
  - Camperdown, New South Wales, Australia, 2050
    - Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders
  - Erina, New South Wales, Australia, 2250
    - Central Coast Neurosciences Research
  - Gosford, New South Wales, Australia, 2250
    - Central Coast Local Health District, Gosford Hospital
  - Maroubra, New South Wales, Australia, 2035
    - Australian Clinical Research Network
- Queensland
  - Chermside, Queensland, Australia, 4032
    - Holy Spirit Northside Private Hospital Limited
  - Herston, Queensland, Australia, 4029
    - Royal Brisbane and Women's Hospital
  - Milton, Queensland, Australia, 4064
    - Core Research Group Pty Ltd
  - Redcliffe, Queensland, Australia, 4020
    - Redcliffe Hospital
  - Sherwood, Queensland, Australia, 4075
    - AusTrials Pty Ltd
  - Southport, Queensland, Australia, 4215
    - Gold Coast University Hospital
- South Australia
  - Ashford, South Australia, Australia, 5035
    - SA Heart
  - Ashford, South Australia, Australia, 5035
    - Adelaide Medical Research
  - Daws Park, South Australia, Australia, 5041
    - Southern Adelaide Diabetes and Endocrine Service
  - Elizabeth Vale, South Australia, Australia, 5112
    - Department of Cardiology, Lyell McEwin Hospital
  - Fullarton, South Australia, Australia, 5063
    - Heart and Vascular Research
- Tasmania
  - Launceston, Tasmania, Australia, 7250
    - Launceston General Hospital
- Victoria
  - Box Hill, Victoria, Australia, 3128
    - Eastern Health - Box Hill Hospital
  - Epping, Victoria, Australia, 3076
    - The Northern Hospital
  - Geelong, Victoria, Australia, 3220
    - Barwon Health-The Geelong Hospital
  - Heidelberg West, Victoria, Australia, 3081
    - Austin Health - Heidelberg Repatriation Hospital
  - Melbourne, Victoria, Australia, 3004
    - Alfred Hospital
- Western Australia
  - Fremantle, Western Australia, Australia, 6160
    - Fremantle Hospital
  - Joondalup, Western Australia, Australia, 6027
    - Joondalup Cardiovascular Trials Foundation Inc.
  - Joondalup, Western Australia, Australia, 6027
    - HPS Pharmacies
Belgium
- - Antwerpen, Belgium, 2020
    - ZNA Campus Middelheim
  - Bonheiden, Belgium, 2820
    - Imeldaziekenhuis Bonheiden
  - Brugge, Belgium, 8000
    - A.Z. St.Jan AV Brugge
  - Brussels, Belgium, 1090
    - University Hospital Brussels - Centrum voor hart- en vaatziekten
  - Brussels, Belgium, 1090
    - University Hospital Brussels- Diabeteskliniek
  - De Pinte, Belgium, 9840
    - Private Practice 'Cardiovascular Detection Center'
  - Genk, Belgium, 3600
    - ZOL Campus Sint-Jan
  - Gent, Belgium, 9000
    - AZ Maria Middelares
  - Gilly, Belgium, 6060
    - Grand Hopital de Charleroi, Site St-Joseph
  - Hasselt, Belgium, 3500
    - Jessa Ziekenhuis
  - Hasselt, Belgium, 3500
    - Hygeia
  - Heusden-Zolder, Belgium, 3550
    - Sint-Franciskusziekenhuis
  - Huy, Belgium, 4500
    - Centre Hospitalier Regional de Huy
  - Ieper, Belgium, 8900
    - Jan Yperman Ziekenhuis, Cardiology
  - La Louviere (Haine-Saint-Paul), Belgium, 7100
    - Centre Hospitalier de Jolimont - Lobbes
  - La Louviere (Haine-Saint-Paul), Belgium, 7100
    - Centre Hospitalier de Jolimont-Lobbes
  - Leuven, Belgium, 3000
    - University Hospitals Leuven
  - Leuven, Belgium, 3000
    - University hospitals Leuven - Neurology department
  - Liege, Belgium, 4000
    - Centre Hospitalier Universitaire (Chu) de Liege
  - Linkebeek, Belgium, 1630
    - Huisartsenpraktijk Medilink
  - Massemen, Belgium, 9230
    - Huisartsenpraktijk Luc Capiau
  - Mons, Belgium, 7000
    - C.H.U. Ambroise Pare
  - Overpelt, Belgium, 3900
    - Mariaziekenhuis vzw
  - Tienen, Belgium, 3300
    - Dr. Luc De Wolf - Private Practice
- Antwerp
  - Mechelen, Antwerp, Belgium, 2800
    - Az Sint-Maarten
- Antwerpen
  - Brasschaat, Antwerpen, Belgium, 2930
    - VZW Algemeen Ziekenhuis KLINA
- Oost-vlaanderen
  - Aalst, Oost-vlaanderen, Belgium, 9300
    - Algemeen Stedelijk Ziekenhuis
  - Dendermonde, Oost-vlaanderen, Belgium, 9200
    - AZ Sint Blasius
  - Gent, Oost-vlaanderen, Belgium, 9000
    - AZ Sint Lucas Gent
  - Gent, Oost-vlaanderen, Belgium, 9000
    - Universitair Ziekenhuis Gent
  - Ronse, Oost-vlaanderen, Belgium, 9600
    - AZ Glorieux
  - Sint-Niklaas, Oost-vlaanderen, Belgium, 9100
    - AZ Nikolaas, Campus Moerland
- West-vlaanderen
  - Kortrijk, West-vlaanderen, Belgium, 8500
    - AZ Groeninge-Campus Loofstraat
  - Oostende, West-vlaanderen, Belgium, 8400
    - AZ Damiaan
Brazil
- - Minas Gerais, Brazil, 30150-240
    - CARDSEARCH/CARDRESEARCH - Cardiologia Assistencial e de Pesquisa LTDA
  - Sao Paulo, Brazil, 01244-030
    - CPClin- Centro de Pesquisas Clinicas Ltda./Clinica Dr. Freddy Goldberg Eliaschewitz
  - Sao Paulo, Brazil, 01327-010
    - FGM-Clinica Paulista de Doencas Cardiovasculares
  - Sao Paulo, Brazil, 04266-010
    - CEPIC - Centro Paulista de Investigacao Clinica e Servicos Medicos Ltda
- BA
  - Salvador, BA, Brazil, 41810-010
    - Fundacao Bahiana de Cardiologia
  - Salvador, BA, Brazil, 41810-011
    - HBA S/A ASSISTENCIA MEDICA E HOSPITALAR-Hospital da Bahia
- CE
  - Fortaleza, CE, Brazil, 60430-140
    - Centro de Pesquisas em Diabetes e Doencas Endocrino-Metabolicas Ltda
- Indiana
  - Indianapolis, Indiana, Brazil, 46214-2985
    - Covance Central Laboratory Services
- Minas Gerais
  - Belo Horizonte, Minas Gerais, Brazil, 30150-240
    - CARDSEARCH/CARDRESEARCH - Cardiologia Assistencial e de Pesquisa LTDA
- PA
  - Belem, PA, Brazil, 66073-000
    - Universidade Federal do Para - Hospital Universitario Joao de Barros Barreto
- PE
  - Recife, PE, Brazil, 52020-010
    - Centro de Pesquisas Médicas Básica e Clínica Ltda
- PR
  - Campina Grande do Sul, PR, Brazil, 83430-000
    - Sociedade Hospitalar Angelina Caron/Hospital e Maternidade Angelina Caron
  - Curitiba, PR, Brazil, 80045-170
    - Quanta Diagnostico e Terapia / Medicina Nuclear Alto da XV
  - Curitiba, PR, Brazil, 80010-030
    - Hospital Santa Casa de Curitiba
- Parana
  - Curitiba, Parana, Brazil, 80730-150
    - Nucleo De Pesquisa Clinica
- Pernambuco
  - Recife, Pernambuco, Brazil, 52051-380
    - Hospital Agamenon Magalhaes
- RIO Grande DO SUL
  - Canoas, RIO Grande DO SUL, Brazil, 92425-055
    - Hospital Universitario - Associacao Educadora Sao Carlos - AESC
  - Porto Alegre, RIO Grande DO SUL, Brazil, 90020-090
    - Irmandade Santa Casa de Misericordia de Porto Alegre
  - Porto Alegre, RIO Grande DO SUL, Brazil, 90110-270
    - Hospital Mae de Deus/Associacao Educadora Sao Carlos AESC / IMV - Instituto de Medicina Vascular
  - Porto Alegre, RIO Grande DO SUL, Brazil, 90620-001
    - Instituto de Cardiologia do Rio Grande do Sul / Fundação Universitária de Cardiologia
  - Porto Alegre, RIO Grande DO SUL, Brazil, 90840-440
    - Hospital Mae de Deus - Instituto do Cancer
  - Porto Alegre, RIO Grande DO SUL, Brazil, 90840-440
    - Hospital Mae de Deus-Associacao Educadora de Sao Carlos-AESC/IMV - Instituto de Medicina Vascular
  - Porto Alegre, RIO Grande DO SUL, Brazil, 90840-440
    - Mae de Deus - Centro de Oncologia Radioterapica (COR)
- RJ
  - Rio de Janeiro, RJ, Brazil, 22271-100
    - CCBR Brasil - Centro de Pesquisa e Analises Clinicas LTDA
- SAO Paulo
  - Campinas, SAO Paulo, Brazil, 13010-001
    - Loema Medicina e Bem Estar- Centro Especializado em Cardiologia Ltda.
  - Sao Jose do Rio Preto, SAO Paulo, Brazil, 15015210
    - IMC - Instituto de Molestias Cardiovasculares/Equipamentos Cardiovasculares Rio Preto Ltda
- SP
  - Campinas, SP, Brazil, 13087-567
    - CAEP - Centro Avancado de Estudos e Pesquisas Ltda.
  - Sao Paulo, SP, Brazil, 05403-010
    - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP)
- Santa Catarina
  - Blumenau, Santa Catarina, Brazil, 89010-906
    - Hospital Santa Isabel
Canada
- - Quebec, Canada, G1V 4W2
    - Clinique des Maladies Lipidiques de Québec
  - Quebec, Canada, G1G 3Y8
    - Recherche Clinique Sigma Inc
- Alberta
  - Calgary, Alberta, Canada, T2H 2G4
    - LMC Diabetes & Endocrinology (Calgary)
  - Calgary, Alberta, Canada, T2N 4Z6
    - Foothills Hospital/University of Calgary
  - Calgary, Alberta, Canada, T2V 4J2
    - Nanji Professional Corporation
- British Columbia
  - Kelowna, British Columbia, Canada, V1Y 1V6
    - The Medical Arts Health Research Group
  - Kelowna, British Columbia, Canada, VlY 1V6
    - Kelowna Cardiology Associates
  - Surrey, British Columbia, Canada, V3V 0C6
    - SMH Cardiology Clinical Trials
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Raymond Dong Inc.
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Stephen S. Cheung Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Dante E. Manyari Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Stephanie Au, Inc.
  - Surrey, British Columbia, Canada, V3W 3C3
    - Dr. Kapil M. Bhagirath Medical Services Corporation
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Richard Bon Inc. & Dr. Adam Yeung Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Stephen Pearce Inc. & Dr. Peter K.H. Tan Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - SMH Cardiology Clinical Trials Inc
  - Surrey, British Columbia, Canada, V3V OC6
    - Dr. Adam Yeung Inc.
  - Surrey, British Columbia, Canada, V3V OC6
    - Dr. Michael Kanakos Inc.
  - Surrey, British Columbia, Canada, V3VOC6
    - Dr. Stephen S. Cheung Inc.
  - Victoria, British Columbia, Canada, V8R 4R2
    - Victoria Heart Institute Foundation
  - Victoria, British Columbia, Canada, V8T 5G4
    - Discovery Clinical Services Ltd.
- Manitoba
  - Winnipeg, Manitoba, Canada, R2H 2A6
    - St. Boniface Hospital
- NF
  - St. John's, NF, Canada, A1B 3V6
    - Health Sciences Centre
  - St. John's, NF, Canada, A1B3V6
    - Health Science Centre
- New Brunswick
  - Moncton, New Brunswick, Canada, E1G 1A7
    - G.A. Research Associates Ltd.
  - Saint John, New Brunswick, Canada, E2L 4L2
    - Cardiology Research Associates of New Brunswick
- Ontario
  - Brampton, Ontario, Canada, L6S 0C9
    - LMC Diabetes & Endocrinology (Brampton)
  - Burlington, Ontario, Canada, L7M 4Y1
    - JBN Medical Diagnostic Services Inc.
  - Burlington, Ontario, Canada, L7M 4Y1
    - Aviva Clinical Trial Group Inc.
  - Burlington, Ontario, Canada, L7R 4E2
    - Philippe R. Beaudry Medicine Professional Corporation
  - Cambridge, Ontario, Canada, N1R 6V6
    - Cambridge Cardiac Care Centre
  - Cambridge, Ontario, Canada, N1R 7R1
    - Vizel Cardiac Research - Saul Vizel Professional Medicine Corporation
  - Collingwood, Ontario, Canada, L9Y 1W3
    - Moran Medical Centre
  - Fort Erie, Ontario, Canada, L2A 1Z3
    - C & L Research
  - Hamilton, Ontario, Canada, L8K 3P3
    - Parkdale Medical Centre
  - London, Ontario, Canada, N6G 2V2
    - Stroke Prevention & Atherosclerosis Research Centre (SPARC)
  - London, Ontario, Canada, N6G2Ml
    - Western University - WCPHFM
  - Markham, Ontario, Canada, L6B 0P9
    - LMC Diabetes & Endocrinology (Markham)
  - Newmarket, Ontario, Canada, L3Y 8C3
    - Newmarket Cardiology Research Group
  - Oakville, Ontario, Canada, L6M 1M1
    - LMC Clinical Research Inc. (Oakville)
  - Oshawa, Ontario, Canada, L1J 2K1
    - The Office of Dr. James Cha
  - Peterborough, Ontario, Canada, K9J 0B2
    - Kawartha Cardiology Clinical Trials
  - Sarnia, Ontario, Canada, N7T 4X3
    - London Road Diagnostic Clinic and Medical Centre
  - Sarnia, Ontario, Canada, N7T 4X3
    - Sarnia Institute of Clinical Research
  - Scarborough, Ontario, Canada, M1E 5E9
    - Scarborough Cardiology Research Associates Inc.
  - Smiths Falls, Ontario, Canada, K7A 4W8
    - Canadian Centre for Research on Diabetes
  - Sudbury, Ontario, Canada, P3E 2N8
    - Brian Y.L. Wong Medicine Professional Corporation
  - Thornhill, Ontario, Canada, L4J 8L7
    - Lmc Diabetes & Endocrinology (Thornhill)
  - Toronto, Ontario, Canada, M9V 4B4
    - Dr. Anil K. Gupta Medicine Professional Corporation
  - Toronto, Ontario, Canada, M3J 2C5
    - Canadian Phase Onward, Inc.
  - Toronto, Ontario, Canada, M3J 1N2
    - JJ Dig Research Ltd
  - Toronto, Ontario, Canada, M4G 3E8
    - Lmc Diabetes & Endocrinology (Bayview)
  - Waterloo, Ontario, Canada, N2T 0C1
    - Dr. Mohan Babapulle Medicine Professional Cooperation
  - Weston, Ontario, Canada, M9N 1W4
    - Dr. Louis Yao, MD Office of
- Quebec
  - Chicoutimi, Quebec, Canada, G7H 7K9
    - Ecogene-21
  - Chicoutimi, Quebec, Canada, G7H 7Y8
    - Q & T Research Chicoutimi
  - Gatineau, Quebec, Canada, J8Y 6S8
    - Q&T Recherche Outaouais Inc.
  - Mirabel, Quebec, Canada, J7J 2K8
    - Omnispec Recherche Clinique Inc.
  - Montreal, Quebec, Canada, H1T 1C8
    - Montreal Heart Institute
  - Montreal, Quebec, Canada, H2Y 1S1
    - Diex Research Montreal, Inc.
  - Sherbrooke, Quebec, Canada, J1G 2E8
    - Centre Hospitalier Universitaire de Sherbrooke - Hotel-Dieu
  - St-Charles-Borromee, Quebec, Canada, J6E 6J2
    - Centre integre de sante et de services sociaux de Lanaudiere (CISSSL)
  - St-Georges, Beauce, Quebec, Canada, G5Y 4T8
    - Centre Integre de Sante et de services sociaux de Chaudiere-Appalaches (CISSA-CA) -
  - St-Jerome, Quebec, Canada, J7Z 5T3
    - CISSS des Laurentides-Point de Service de St-Jerome- Comite d'ethique de la recherche
  - St-Jerome, Quebec, Canada, J7Z 5T3
    - St-Jerome Medical Research Inc.
  - Trois-Rivieres, Quebec, Canada, G8T 7A1
    - C.I.C. Mauricie Inc.
  - Ville Saint-Laurent, Quebec, Canada, H4T 1Z9
    - LMC Clinical Research Inc. (Montreal)
Chile
- - Puerto Varas, Chile, 5550170
    - Quantum Research
  - Santiago, Chile, 8053095
    - Hospital y CRS El Pino
- Metropolitana
  - Providencia Santiago, Metropolitana, Chile, 7500710
    - BioMedica Research Group
  - Santiago, Metropolitana, Chile, 7500021
    - CICAB
  - Santiago, Metropolitana, Chile, 7500739
    - SMOLAM
  - Santiago, Metropolitana, Chile, 8207257
    - Complejo Asitencial Dr. Sotero del Rio
- Region DE LA Araucania
  - Temuco, Region DE LA Araucania, Chile, 4781156
    - Centro de Investigacion Clinica del Sur
- Region DE LOS Lagos
  - Osorno, Region DE LOS Lagos, Chile, 5311092
    - Corporacion de Beneficencia Osorno
- Region Metropolitana
  - Santiago, Region Metropolitana, Chile, 7500710
    - Servicios Medicos Godoy
Colombia
- Antioquia
  - Medellin, Antioquia, Colombia, 00000
    - Hospital Pablo Tobon Uribe
  - Medellin, Antioquia, Colombia
    - Centro de Investigacion Clinica Avanzada y Multidisciplinaria CICLAM
  - Medellin, Antioquia, Colombia, 50012
    - Rodrigo Botero S.A.S
  - Medellin, Antioquia, Colombia
    - Centro de Medicina del Ejercicio y Rehabilitacion Cardiaca S.A. CEMDE S.A.
- Atlantico
  - Barranquila, Atlantico, Colombia
    - Clinica de la Costa Ltda
  - Barranquilla, Atlantico, Colombia, 80020
    - Centro Cientifico Asistencial Jose Luis Accini S.A.S.
  - Barranquilla, Atlantico, Colombia
    - Fundacion del Caribe para la Investigacion Biomedica - Fundacion BIOS
  - Barranquilla, Atlantico, Colombia, 80020
    - Corazón IPS S.A.S.
  - Barranquilla, Atlantico, Colombia
    - Corozan Ips Sas
- Bolivar
  - Cartagena, Bolivar, Colombia
    - Centro de Diagnostico Cardiologico LTDA.
- Caldas
  - Manizales, Caldas, Colombia
    - Asociacion IPS Medicos Internistas de Caldas
- Cundinamarca
  - Bogota D.C, Cundinamarca, Colombia, 110221
    - Dexadiab Servicios Medicos LTDA
  - Bogota D.C, Cundinamarca, Colombia, 111211
    - Caja de Compensacion Familiar CAFAM, Sede Centro de Atencion en Salud CAFAM FLORESTA
  - Bogota D.C, Cundinamarca, Colombia
    - Hospital Universitario San Ignacio
  - Bogota D.C, Cundinamarca, Colombia
    - Instituto de Investigacion Endocrinologia y Prevencion Metabolica - ENDOCARE LTDA.
  - Bogota D.C., Cundinamarca, Colombia, 110911
    - Medplus Medicina Prepagada S.A.
  - Bogota D.C., Cundinamarca, Colombia
    - Solano & Terront Servicios Medicos Ltda-Establecimiento Comercial UNIENDO
- Santander
  - Bucaramanga, Santander, Colombia
    - Instituto del Corazon de Bucaramanga S.A.
  - Floridablanca, Santander, Colombia
    - Fundación Cardiovacular de Colombia - Instituto del Corazón de Floridablanca
- Valle DEL Cauca
  - Cali, Valle DEL Cauca, Colombia, 760001
    - Fundación Reina Isabel
Czechia
- - Brno, Czechia, 602 00
    - CCBR Czech Brno, s.r.o.
  - Havirov, Czechia, 73601
    - DIKa centrum s.r.o., Kardiologicka a interni ambulance
  - Hradec Kralove, Czechia, 500 05
    - Fakultni nemocnice Hradec Kralove
  - Hradec Kralove, Czechia, 500 05
    - Fakultni nemocnice Hradec Kralove, III. Interni gerontometabolicka klinika
  - Litovel, Czechia, 784 01
    - Kardio Interna s.r.o.
  - Olomouc, Czechia, 77520
    - Fakultni Nemocnice Olomouc
  - Olomouc, Czechia, 775 00
    - Fakultni Nemocnice Olomouc
  - Pardubice, Czechia, 530 02
    - CCBR Czech a.s.
  - Plzen, Czechia, 326 00
    - Kardiologie Plzen s.r.o.
  - Praha, Czechia, 14059
    - Centrum kardiovaskularni prevence 1. LF UK a TN
  - Praha 2, Czechia, 128 08
    - Fakultní poliklinika Všeobecné fakultní nemocnice v Praze
  - Praha 3, Czechia, 130 00
    - CCBR Czech Prague, s.r.o
  - Praha 5, Czechia, 158 00
    - Kardiologie a interni lekarstvi
  - Praha 6, Czechia, 160 00
    - NEFROMED, s.r.o.
  - Roznov pod Radhostem, Czechia, 756 61
    - Interna a kardiologie s.r.o.
  - Svitavy, Czechia, 568 25
    - Nemocnice Pardubickeho kraje, a.s., Svitavska nemocnice
  - Tabor, Czechia, 390 03
    - Vseobecna kardiologicka ambulance s.r.o.
  - Tabor, Czechia, 39003
    - Lekarna U Nemocnice
  - Uherske Hradiste, Czechia, 686 01
    - Lekarna Hradebni s.r.o.
  - Uherske Hradiste 1, Czechia, 686 01
    - MUDr. Antonin Dufka, kardiologicka ambulance
  - Uherske Hradiste 1, Czechia, 686 01
    - MUDr. Nina Zemkova s.r.o.
  - Znojmo, Czechia, 66902
    - KIGE s.r.o.
- Czech Republic
  - Litovel, Czech Republic, Czechia, 78401
    - FREMLOVA APHOTECA s.r.o.
  - Pardubice, Czech Republic, Czechia, 530 02
    - BENU Lekarna
- Jihomoravsky KRAJ
  - Brno, Jihomoravsky KRAJ, Czechia, 638 00
    - Kardiologicka ambulance
- Kralovehradecky KRAJ
  - Broumov, Kralovehradecky KRAJ, Czechia, 55001
    - EDUMED s.r.o.
  - Jaromer, Kralovehradecky KRAJ, Czechia, 550 01
    - EDUMED s.r.o.
  - Trutnov, Kralovehradecky KRAJ, Czechia, 54101
    - Kardiologicka ambulance
  - Trutnov, Kralovehradecky KRAJ, Czechia, 54101
    - Lekarna na Poliklinice
- Moravskoslezsky KRAJ
  - Ostrava, Moravskoslezsky KRAJ, Czechia, 70200
    - MUDr. Jan Vrkoc s.r.o.
- Pardubicky KRAJ
  - Pardubice, Pardubicky KRAJ, Czechia, 53002
    - PV-Kardiologie s.r.o.
Denmark
- - Aabenraa, Denmark, 6200
    - Sygehus Sonderjylland Aabenraa
  - Aalborg, Denmark, 9000
    - Aalborg Universitetshospital, Lipidklinikken
  - Aalborg, Denmark, 9000
    - CCBR Aalborg
  - Aarhus, Denmark, 8200
    - Aarhus Universitetshospital Skejby, Hjertesygdomme ¿ Klinisk Forskning
  - Aarhus N, Denmark, 8250
    - Aarhus Universitetshospital
  - Ballerup, Denmark, 2750
    - CCBR Ballerup
  - Copenhagen NV, Denmark, 2400
    - Bispebjerg Og Frederiksberg Hospital
  - Copenhagen Oe, Denmark, 2100
    - Rigshospitalet
  - Esbjerg, Denmark, 6700
    - Sydvestjysk Sygehus
  - Frederiksberg, Denmark, 2000
    - Frederiksberg Hospital
  - Glostrup, Denmark, 2600
    - Glostrup Hospital
  - Herlev, Denmark, 2730
    - Herlev Universitetshospital, Kardiologisk afdeling S
  - Herning, Denmark, 7400
    - Regionshospitalet Herning
  - Hillerod, Denmark, 3400
    - Hillerod Hospital
  - Hvidovre, Denmark, 2650
    - Hvidovre Universitetshospital, Hjerte-lungemedicinsk afdeling
  - Kobenhavn S., Denmark, 2300
    - Amager Hospital
  - Koge, Denmark, 4600
    - Region Sjaelland Sygehus Nord, Koge Sygehus
  - Kolding, Denmark, 6000
    - Kolding Sygehus
  - Naestved, Denmark, 4700
    - Region Sjaelland Naestved Sygehus
  - Nykobing F., Denmark, 4800
    - Nykobing F. Sygehus-Medicinsk afdeling
  - Randers, Denmark, 8930
    - Regionshospitalet Randers
  - Silkeborg, Denmark, 8600
    - Regionshospitalet Silkeborg, Hjerte Projektkontor
  - Slagelse, Denmark, 4200
    - Slagelse Sygehus
  - Svendborg, Denmark, 5700
    - Svendborg Sygehus
  - Vejle, Denmark, DK 7100
    - CCBR Vejle
  - Viborg, Denmark, 8800
    - Hospitalsenheden Midt, Regionshospital Viborg
Finland
- - Hameenlinna, Finland, 13100
    - Linnan Klinikka Oy
  - Helsinki, Finland, 00290
    - Helsinki University Central Hospital
  - Helsinki, Finland, FI-00290
    - Helsingin yliopistollinen keskussairaala, Sisaetaudit ja kuntoutus, Biomedicum 2U
  - Helsinki, Finland, 00260
    - Mehiläinen Töölö
  - Joensuu, Finland, 80100
    - Ita-Suomen laakarikeskus Oy
  - Jyvaskyla, Finland, 40620
    - StudyCor Oy
  - Kerava, Finland, 04200
    - Laeaekaerikeskus Aava Kerava
  - Kinkomaa, Finland, 40930
    - Menoa oy
  - Kokkola, Finland, 67200
    - Kokkolan Keskussairaala
  - Kotka, Finland, 48600
    - Mewell liikuntaklinikka
  - Kuopio, Finland, 70100
    - Terveystalo Kuopio
  - Kuopio, Finland, 70100
    - Itae-Suomen Laeaekaeritalo Oy
  - Oulu, Finland, 90220
    - Oulu University Hospital
  - Oulu, Finland, 90100
    - Oulu Mentalcare Oy
  - Oulu, Finland, 90100
    - Terveystalo Oulu, Diapolis
  - Pori, Finland, 28100
    - Porin Lääkäritalo Oy
  - Siilinjarvi, Finland, 71800
    - Terveystalo Siilinjarvi
  - Tampere, Finland, 33520
    - FinnMedi Oy
  - Turku, Finland, 20520
    - Turku University Hospital
  - Turku, Finland, 20100
    - Terveystalo Pulssi
  - Vantaa, Finland, 01600
    - Vantaan Tutkimuskeskus
France
- - Besancon, France, 25000
    - CHU Jean Minjoz Cardiologie
  - Bourg En Bresse Cedex 10000, France, 01012
    - Centre Hospitalier De Bourg En Bresse - Hopital Fleyriat
  - Caen cedex 9, France, 14033
    - CHU de Caen
  - Cannes Cedex, France, 06414
    - Centre Hospitalier de Cannes- Service de Cardiologie
  - Corbeil-Essonnes, France, 91106
    - Centre Hospitalier Sud-Francilien
  - Essey-Les-Nancy, France, 54270
    - Scp Cardiovasculaire De L'Est
  - Le Coudray, France, 28630
    - Centre Hospitalier Louis Pasteur
  - Lille, France, 59000
    - Hôpital La Louvière
  - Lomme, France, 59462
    - Centre Hospitalier Saint Philibert
  - Lyon Cedex 03, France, 69394
    - Hopital Cardiovasculaire et Pneumologique Louis Pradel
  - Montpellier cedex 5, France, 34295
    - Hopital Arnaud de Villeneuve
  - Nantes, France, 44093
    - CHU de Nantes - Hôpital Nord Laennec
  - Nantes, France, 44200
    - Nouvelles Cliniques Nantaises
  - Nimes, France, 30000
    - CHU Caremeau
  - Nimes cedex 9, France, 30029
    - CHU Caremeau
  - PAU, France, 64046
    - Centre Hospitalier de Pau
  - Pessac cedex, France, 33604
    - Hopital Cardiologique
  - Poitiers cedex, France, 86021
    - CHU de Poitiers
  - Rennes Cedex 9, France, 35033
    - CHU de Renes Hopital de Pontchaillou
  - Toulouse cedex 9, France, 31059
    - CHU de Toulouse
  - Tourcoing, France, 59200
    - Hopital Guy Chatiliez
  - Tours Cedex 9, France, 37044
    - Hopital Trousseau
  - Valenciennes, France, 59300
    - Polyclinique Vauban
  - Valenciennes, France, 59300
    - Centre Hospitalier (CH) de Valenciennes
Germany
- - Altenburg, Germany, 04600
    - Klinikum Altenburger Land GmbH
  - Bad Berka, Germany, 99437
    - Zentralklinik Bad Berka GmbH
  - Bad Homburg, Germany, 61348
    - Forschungszentrum Dr. med Irma Schoell
  - Berlin, Germany, 13353
    - Deutsches Herzzentrum Berlin
  - Berlin, Germany, 10117
    - Klinische Forschung Berlin-Mitte GmbH
  - Berlin, Germany, 12627
    - Synexus Clinical Research GmbH
  - Berlin, Germany, 10115
    - Institut fuer Klinische Forschung und Entwicklung(IKFE) Berlin GmbH
  - Berlin, Germany, 13597
    - Medizinisches Versorgungszentrum am Bahnhof Spandau
  - Berlin, Germany, 12157
    - POLIKUM Institut GmbH
  - Berlin, Germany, 12559
    - DRK Kliniken Kopenick, Zentrum Klinische Forschung
  - Berlin, Germany, 12627
    - Berlin Research Centre-Synexus Clinical Research GmbH
  - Bielefeld, Germany, 33604
    - Klinikum Bielefeld
  - Bochum, Germany, 44787
    - Bochum Research Centre-Synexus Clinical Research GmbH
  - Burg-Spreewald, Germany, 03096
    - MediClin Reha-Zentrum Spreewald
  - Coburg, Germany, 96450
    - Klinikum Coburg
  - Dachau, Germany, 85221
    - Helios Amper-Klinikum Dachau
  - Dortmund, Germany, 44137
    - St. Johannes-Hospital
  - Dortmund, Germany, 44137
    - Kardiologische Praxisgemeinschaft
  - Dortmund, Germany, 44141
    - Gemeinschaftspraxis fuer Kardiologie Dres. Med. Willgeroth/Wetzel
  - Dresden, Germany, 01069
    - Klinsche Forschung Dresden GmbH
  - Dresden, Germany, 01277
    - Praxis Dr. med. Christoph Axthelm
  - Dresden, Germany, 01307
    - GWT-TUD GmbH, Studienzentrum Professor Hanefeld
  - Essen, Germany, 45355
    - Medizentrum Essen Borbeck
  - Essen, Germany, 45355
    - Gemeinschaftspraxis Dr. Hagemann/Breiderhoff/Durfeld
  - Essen, Germany, 45355
    - Studienzentrum
  - Essen, Germany, 45359
    - Gemeinschaftspraxis Dres. Dirk Weber, Ulrich Weber, Heiner Saueressig, Birte Turner und Georg
  - Falkensee, Germany, 14612
    - Schwerpunktpraxis Dr. Luedemann fuer Diabetes Gefaess- und Ernaehrungsmedizin
  - Frankfurt, Germany, 60 594
    - ClinPhenomics GmbH & Co KG, Studienzentrum
  - Frankfurt, Germany, 60596
    - Synexus Clinical Research GmbH
  - Frankfurt am Main, Germany, 60596
    - IKF Institut fuer klinische Forschung Frankfurt
  - Greifswald, Germany, 17475
    - Klinik und Poliklinik fuer Innere Medizin B-Kardiologie, Angiologie, Pulmologie, Internistische
  - Hamburg, Germany, 22041
    - Cardiologicum Hamburg
  - Hamburg, Germany, 22415
    - Praxis Dr. med Cornelia Brauer
  - Hannover, Germany, 30159
    - Klinische Forschung Hannover-Mitte GmbH
  - Homburgsaar, Germany, 66421
    - Universitatsklinikum des Saarlandes Klinik fur Innere Medizin III
  - Kamp-Lintfort, Germany, 47475
    - Praxis Dr. Heister
  - Kassel, Germany, 34121
    - Studienzentrum Dr. Appel
  - Koeln, Germany, 51069
    - Zentrum fuer klinische Forschung
  - Kuenzing, Germany, 94550
    - Gemeinschaftspraxis Dr. Klein / Minnich
  - Lahr, Germany, 77933
    - Klinik fur Innere Medizin, Kardiologie und Angiologie MediClin Herzzentrum Lahr/Baden.
  - Leipzig, Germany, 04249
    - Gemeinschaftspraxis Dr. med. Heidrun Taeschner und Dr. med. Susanne Bonigut
  - Leipzig, Germany, 04103
    - Synexus Clinical Research GmbH
  - Leipzig, Germany, 04103
    - Synexus Leipzig Clinical Research Centre
  - Leipzig, Germany, 04109
    - Polikum Institut Leipzig GmbH
  - Luedenscheid, Germany, 58515
    - Maerkische Kliniken GmbH, Klinikum Luedenscheid, Innere III
  - Lunen, Germany, 44534
    - Klinikum Lunen, St. Marienhospital
  - Magdeburg, Germany, 39120
    - SMO.MD GmbH, Zentrum fuer klinische Studien Site Management and Clinical Research Unit
  - Magdeburg, Germany, 39120
    - SMO.MD GmbH - Zentrum fÃ¼r klinische Studien
  - Mainz, Germany, 55116
    - Pfuetzner Science & Health Institute-Gmbh
  - Muenchen, Germany, 80636
    - Klinikum fuer Herz- & Kreislauferkrankungen
  - Munchen, Germany, 80336
    - Klinikum der Universität München
  - Munich, Germany, 81737
    - Staedtisches Klinikum Muenchen GmbH
  - Northeim, Germany, 37154
    - Kardiologische Praxis Northeim
  - Nurnberg, Germany, 90402
    - Gemeinschaftspraxis Drs Haggenmiller/Jeserich, Kardiologie, Angiologie, Innere Medizin
  - Offenbach, Germany, 63071
    - Allgemeinmedizinisch-Internistische Praxisgemeinschaft
  - Rodgau, Germany, 63110
    - Praxis Dres. Med Naudts und Nowack
  - Rudersdorf, Germany, 15562
    - Klinik am See Rehabilitationszentrum fur Innere Medizin
  - Soest, Germany, 59494
    - Kardiologische Gemeinschaftspraxis Dres Med. Gerke/Burger
  - Stuhr-Brinkum, Germany, 28816
    - Praxisgemeinschaft Stuhr-Brinkum
  - Stuttgart, Germany, 70376
    - Robert-Bosch-Krankenhaus
  - Warendorf, Germany, 48231
    - Josephs-Hospital Warendorf Med. Klinik II, Kardiologie/Angiologie
  - Wermsdorf, Germany, 04779
    - Kardiologische Praxis
  - Witten, Germany, 58455
    - ForschungszentrumRuhr KliFoCenter GmbH
- Baden-wuerttemberg
  - Bad Krozingen, Baden-wuerttemberg, Germany, 79189
    - Universitaets Herzzentrum Freiburg Bad Krozingen
- Baden-wurttemberg
  - Heidelberg, Baden-wurttemberg, Germany, 69120
    - Medizinische Universtatsklinik Heidelberg
  - Mannheim, Baden-wurttemberg, Germany, 68165
    - ze:ro ARZTPRAXEN
- Hessen
  - Fulda, Hessen, Germany, 36037
    - Gemeinschaftspraxis im Altstadt Carree
- Mecklenburg-vorpommern
  - Schwerin, Mecklenburg-vorpommern, Germany, 19055
    - Klinische Forschung Schwerin GmbH
- Rheinland Pfalz
  - Neuwied, Rheinland Pfalz, Germany, 56564
    - Zentrum Klinische Studien Neuwied (ZKSN)
- Rhineland-palatinate
  - Schwabenheim, Rhineland-palatinate, Germany, 55270
    - Gemeinschaftspraxis Schwabenheim
Hungary
- - Balatonfured, Hungary, 8230
    - DRC Kft.
  - Balatongyorok, Hungary, 8313
    - DRC Kft.
  - Bekescsaba, Hungary, 5600
    - Kardiologiai Maganrendelo
  - Berettyoujfalu, Hungary, 4100
    - Grof Tisza Istvan Korhaz Berettyoujfalu
  - Budapest, Hungary, 1088
    - Semmelweis Egyetem
  - Budapest, Hungary, 1096
    - Gottsegen György Országos Kardiológiai Intézet
  - Budapest, Hungary, 1036
    - Synexus Magyarorszag Kft
  - Budapest, Hungary, 1125
    - Semmelweis Egyetem
  - Budapest, Hungary, 1021
    - Budapesti Szent Ferenc Korhaz
  - Budapest, Hungary, 1085
    - Szent Rokus Korhaz
  - Budapest, Hungary, 1097
    - Egyesitett Szent Istvan es Szent Laszlo Korhaz-Rendelointezet
  - Budapest, Hungary, 1125
    - Szent Janos Korhaz es Eszak-budai Egyesitett Korhazak, III. Belgyogyaszat-Kardiologiai Osztaly
  - Budapest, Hungary, 1097
    - Egyesitett Szent Istvan Korhaz es Szent Laszlo Korhaz
  - Debrecen, Hungary, 4032
    - Debreceni Egyetem
  - Gyula, Hungary, 5700
    - Synexus Magyarorszag Kft.
  - Hajduszoboszlo, Hungary, 4200
    - Edes Szivunk Egeszsegkozpont Kft.
  - Hatvan, Hungary, 3000
    - BKS Research Kft., Albert Schweitzer Korhaz
  - Kaposvar, Hungary, 7400
    - Somogy Megyei Kaposi Mór Oktató Kórház
  - Kecskemet, Hungary, 6000
    - Jutrix Egeszsegugyi Kft
  - Kistarcsa, Hungary, 2143
    - Pest Megyei Flor Ferenc Korhaz
  - Kistarcsa, Hungary, 2143
    - Megyei Flor Ferenc Korhaz
  - Nyiregyhaza, Hungary, 4400
    - Medifarma-98 Kft.
  - Nyiregyhaza, Hungary, 4400
    - Jósa András Oktatókórház
  - Pecs, Hungary, 7624
    - Pecsi Tudomanyegyetem AOK, I. Belgyogyaszati Klinika
  - Szekesfehervar, Hungary, 8000
    - Mentahaz Maganorvosi Kozpont
  - Szolnok, Hungary, 5000
    - Hetényi Géza Kórház
  - Szombathely, Hungary, 9700
    - Markusovszky Egyetemi Oktatokarhaz
  - Veszprem, Hungary, 8200
    - Dr. Sydo es Tsa Kft.
  - Zalaegerszeg, Hungary, 8900
    - Zala Megyei Kórház
  - Zalaegerszeg, Hungary, 8900
    - Zala Megyei Korhaz, Diabetológiai Szakrendelés
- Bacs-kiskun
  - Kecskemet, Bacs-kiskun, Hungary, 6000
    - Bacs-kiskun Megyei Korhaz
- Baranya
  - Pecs, Baranya, Hungary, 7624
    - Pecsi Tudomanyegyetem AOK, II.
- Csongrad
  - Szeged, Csongrad, Hungary, 6720
    - Szegedi Tudomanyegyetem AOK, I. sz Belgyogyaszati Klinika
- Fejer
  - Szekesfehervar, Fejer, Hungary, 8000
    - Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz
India
- Gujarat
  - Ahmedabad, Gujarat, India, 380007
    - Dr. Jivraj Mehta Smarak Health Foundation, Bakeri Medical Research Centre
  - Ahmedabad, Gujarat, India, 380054
    - Apex Heart Institute (A Unit of TCVS Pvt. Ltd)
  - Ahmedabad, Gujarat, India, 380054
    - SAL Hospital
  - Surat, Gujarat, India, 395 002
    - Apple Hospital
  - Surat, Gujarat, India, 395002
    - Unicare Heart Institute & Research Center
  - Surat, Gujarat, India, 395009
    - BAPS - Pramukh Swami Hospital
  - Vadodara, Gujarat, India, 390022
    - Rhythm Heart Institute
- Maharashtra
  - Pune, Maharashtra, India, 411001
    - Jehangir Clinical Development Centre Pvt. Ltd.
- Uttar Pradesh
  - Lucknow, Uttar Pradesh, India, 226003
    - M.V. Hospital and Research Centre
Ireland
- - Dublin, Ireland, 8
    - St James's Hospital
- Leinster
  - Dublin, Leinster, Ireland, 9
    - Beaumont Hospital
Israel
- - Ashkelon, Israel, 7830604
    - Barzilai Medical Center
  - Beer Sheva, Israel, 84350
    - Ben Yair Community Clinic - Clalit Health Services
  - Hadera, Israel, 38100
    - Heart Institute, Hillel Yaffe Medical Center
  - Haifa, Israel, 31096
    - Rambam Medical Center
  - Haifa, Israel, 34362
    - Cardiovascular Clinical Research Institute
  - Holon, Israel, 58100
    - Edith Wolfson Medical Center
  - Jerusalem, Israel, 91120
    - Hadassah Ein Kerem Medical Center
  - Kfar Sava, Israel, 44281
    - Meir Medical Center
  - Kfar-Saba, Israel, 44281
    - Meir Medical Center
  - Nahariya, Israel, 22100
    - Galilee Medical Center, Cardiology Department
  - Nazareth, Israel, 16100
    - E.M.M.S Nazareth Hospital
  - Petach Tikva, Israel, 4958202
    - Sha'aria Clinic, Clalit Health Services
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center, Beilinson Hospital
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center-Beilinson Hospital
  - Raanana, Israel, 43452
    - Shuali Community Clinic, Clalit Health Services
  - Ramat Gan, Israel, 52621
    - Department of Neurology & Sagol Neuroscience Center
  - Rehovot, Israel, 76100
    - Heart Institute, Kaplan Medical Center
  - Rehovot, Israel, 76100
    - Kaplan Medical Center Metabolism and Diabetes Clinic, Kaplan Medical Center
  - Safed, Israel, 13100
    - Ziv Medical Center
  - Safed, Israel, 13100
    - Internal Medicine A, Ziv Medical Center
  - Tel Aviv, Israel, 6789140
    - Assuta Medical Center
  - Tel Hashomer, Israel, 5265601
    - The Chaim Sheba Medical Center
  - Tel-Aviv, Israel, 64239
    - Tel Aviv Sourasky Medical Center
- Tel-aviv
  - Tel Aviv, Tel-aviv, Israel, 64239
    - Tel Aviv Sourasky Medical Center
Italy
- - Ancona, Italy, 60124
    - S. C. Cardiologia INRCA
  - Belluno, Italy, 32100
    - Ospedale Civile Regionale San Martino, Belluno
  - Cagliari, Italy, 09124
    - Azienda Ospedaliera G. Brotzu
  - Milan, Italy, 20138
    - Unità Operativa Solventi e Unità Poliambulatorio
  - Napoli, Italy, 80131
    - Department of Clinical Medicines and Cardiovascular Sciences, Universita "Federico II" di Napoli
  - Napoli, Italy, 80131
    - Divisione di Cardiologia con Utic ed Emodinamica - AOU Federico II di Napoli
  - Reggio Emilia, Italy, 42123
    - A.O. di Reggio Emilia Arcispedale "S. Maria Nuova"/IRCCS
  - Rimini, Italy, 47923
    - AUSL Della Romagna-Ospedale Infermi
  - Rovigo, Italy, 45100
    - Ospedale Santa Maria della Misericordia Azienda ULSS 18 of Rovigo
  - Udine, Italy, 33100
    - Azienda Ospedaliera Universitaria Santa Maria della Misericordia
- Bergamo
  - Treviglio (BG), Bergamo, Italy, 24047
    - A.O. Treviglio e Caravaggio
- CZ
  - Catanzaro, CZ, Italy, 88100
    - AOU Policlinico "Mater Domini" UOC di Medicina Interna
- Geneve
  - Meyrin/Geneve, Geneve, Italy, 1217
    - Covance Central Laboratory Services
- Lecco
  - Merate, Lecco, Italy, 23807
    - Ospedale S. L. Mandic di Merate
- PA
  - Palermo, PA, Italy, 90127
    - Dipartimento delle Patologie Emergenti, Unita di Medicina Interna e Dislipidemie Genetiche
- PG
  - Perugia, PG, Italy, 06132
    - Ospedale S. Maria della Misericordia -Dipartimento di Medicina, Medicina Interna,
- Province OF Lecco
  - Lecco, Province OF Lecco, Italy, 23900
    - Azienda Ospedaliera Della Provincia Di Lecco - Ospedale Manzoni
- RM
  - Roma, RM, Italy, 00161
    - Dip Medicina Interna e Specialita Mediche, Policlinico Umberto I
  - Rome, RM, Italy, 00161
    - Policlinico Umberto I Di Roma
  - Rome, RM, Italy, 00189
    - Azienda Ospedaliera S'Andrea di Roma - UOC Cardiologia
- VR
  - Verona, VR, Italy, 37126
    - AOUI di Verona - Ospedale Civile Maggiore Borgo Trento
- Verona
  - San Bonifacio, Verona, Italy, 37047
    - Ospedale G. Fracastoro
Korea, Republic of
- - Busan, Korea, Republic of, 49201
    - Dong-A University Hospital
  - Busan, Korea, Republic of, 47392
    - Inje University Busan Paik Hospital
  - Daegu, Korea, Republic of, 42472
    - Daegu Catholic University Medical Center
  - Incheon, Korea, Republic of, 21565
    - Gachon University Gil Medical Center
  - Seoul, Korea, Republic of, 05505
    - Asan Medical Center
  - Seoul, Korea, Republic of, 134-701
    - Hallym University Kangdong Sacred Heart Hospital
  - Seoul, Korea, Republic of, 131-795
    - Seoul Medical Center
  - Seoul, Korea, Republic of, 135-720
    - Gangnam Severance Hospital, Yonsei University Health System
  - Seoul, Korea, Republic of, 137-701
    - The Catholic University Of Korea Seoul St.Marys Hospital
  - Seoul, Korea, Republic of, 156-707
    - Seoul Metropolitan Government - Seoul National University Boramae Medical Center
- Chungcheonbuk-do
  - Cheongju-si, Chungcheonbuk-do, Korea, Republic of, 362-711
    - Chungbuk National University Hospital
- Gangwon-do
  - Chuncheon-si, Gangwon-do, Korea, Republic of, 24289
    - Kangwon National University Hospital
  - Wonju-Si, Gangwon-do, Korea, Republic of, 26426
    - Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital
  - Wonju-si, Gangwon-do, Korea, Republic of, 26426
    - Yonsei University Wonju Severance Christian Hospital
- Gyeongbuk
  - Gyeongju-si, Gyeongbuk, Korea, Republic of, 780-350
    - Donguk University Gyeongju Hospital
- Gyeonggi-do
  - Goyang-Si, Gyeonggi-do, Korea, Republic of, 10380
    - Inje University Ilsan Paik Hospital
  - Goyang-si, Gyeonggi-do, Korea, Republic of, 10326
    - Dongguk University Ilsan Hospital
  - Goyang-si, Gyeonggi-do, Korea, Republic of, 10475
    - Myongji Hospital
  - Seongnam-si, Gyeonggi-do, Korea, Republic of, 13620
    - Seoul National University Bundang Hospital
  - Suwon-si, Gyeonggi-do, Korea, Republic of, 443-380
    - Ajou University Hospital
  - Uijeongbu-si, Gyeonggi-do, Korea, Republic of, 11765
    - Uijeongbu St. Mary's Hospital-The Catholic University of Korea
Mexico
- - Aguascalientes, Mexico, 20230
    - Hospital Cardiologica Aguascalientes
  - Aguascalientes, Mexico, 20127
    - Instituto Biomedico De Investigacion A.C.
  - Chihuahua, Mexico, 31217
    - Investigacion en Salud y Metabolismo S.C
  - Chihuahua, Mexico, 31203
    - Unidad de Investigacion en Salud de Chihuahua S.C.
  - Chihuahua, Mexico, 31217
    - Consultorio Medico de Especialidad Dr. Demetrio Kosturakis Garcia
  - Distrito Federal, Mexico, 14000
    - Instituto Nacional de Ciencia Medicas y Nutricion Salvador Zubiran
  - Durango, Mexico, 34000
    - Lahoja Asociación para la Investigación y Farmacovigilancia S.C.
  - Mexico, Mexico, 11650
    - Centro Especializado en Diabetes, Obesidad y Prevención de Enfermedades Cardiovasculares, S.C.
  - Queretaro, Mexico, 76000
    - Pharmacology and Clinical Research S.A. de C.V.
  - San Luis Potosi, Mexico, 78200
    - Cardioarritmias e Investigación S.C.
  - San Luis Potosi, Mexico, 78218
    - Hospital Lomas de San Luis lntemacional (Emergencies)
  - San Luis Potosi, Mexico, 78240
    - Hospital Central "Dr. Ignacio Morones Prieto"
  - Veracruz, Mexico, 91910
    - Centro Especializado En Diabetes Y Metabolismo
- Chihuahua
  - Cd. Juarez, Chihuahua, Mexico, 32472
    - Consultorio Dr. Leocadio Gerardo Munoz Beltran
- DF
  - Mexico, DF, Mexico, 11650
    - Centro Especializado en Diabetes Obesidad y Prevencion de Enfermedades Cardiovasculares, SC.
- Distrito Federal
  - Mexico, Distrito Federal, Mexico, 07760
    - Consultorio de Endocrinologia y Nutriologia
  - Mexico, Distrito Federal, Mexico, 14000
    - Instituto Nacional de Ciencias Médicas y Nutricion "Salvador Zubiran"
  - Mexico, Distrito Federal, Mexico, 07760
    - Operadora de Hospitales Angeles S.A. de C.V. (Emergencies)
- Guerrero
  - Acapulco, Guerrero, Mexico, 39670
    - Hospital Del Pacifico,Centro De Investigacion Clinica Del Pacifico Cicpa,Torre Medica Del Pacifico
  - Acapulco de Juarez, Guerrero, Mexico, 39670
    - Centro de Investigacion Clinica del Pacifico, S.A. de C.V.
- Hidalgo
  - Pachuca, Hidalgo, Mexico, 42090
    - Investigacion Biomedica Aplicada de Hidalgo S.A. de C.V.
  - Pachuca de Soto, Hidalgo, Mexico, 42070
    - Clinical Trials Mexico, S.A. de C.V.
- Jalisco
  - Guadalajara, Jalisco, Mexico, 44160
    - Centro de Investigación Médica Integral S.C.
  - Guadalajara, Jalisco, Mexico, 44657
    - Consultorio Privado del Dr. Gabriel Arturo Ramos Lopez
  - Guadalajara, Jalisco, Mexico, 44600
    - Icle S.C.
  - Guadalajara, Jalisco, Mexico, 44760
    - Unidad de Investigacion Clinica y Atencion Medica HEPA S.C.
- Morelos
  - Cuernavaca, Morelos, Mexico, 62250
    - Instituto de Diabetes Obesidad y Nutricion, S.C.
  - Cuernavaca, Morelos, Mexico, 62270
    - Hospital Inovamed Cuernavaca (Emergencies)
- Nuevo LEON
  - Monterrey, Nuevo LEON, Mexico, 64460
    - Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
  - Monterrey, Nuevo LEON, Mexico, 64718
    - Global Trial Research Center S.A. de C.V.
  - Monterrey, Nuevo LEON, Mexico, 64060
    - Cardiolink Clin Trials, S.C.
  - Monterrey, Nuevo LEON, Mexico, 64710
    - CRI Centro Regiomontano de Investigacion SC
- Queretaro
  - San Juan del Rio, Queretaro, Mexico, 76800
    - Centro Integral Medico SJR S.C
- Sinaloa
  - Culiacan, Sinaloa, Mexico, 80020
    - Centro Para El Desarrollo de La Medicina Y de Asistencia Medica Especializada S.C.
  - Culiacan, Sinaloa, Mexico, 80020
    - Hospital Angeles Culiacan
- Tamaulipas
  - Tampico, Tamaulipas, Mexico, 89000
    - Centro de Estudios de Investigación Metabólicos y Cardiovasculares S.C.
- Veracruz
  - Xalapa, Veracruz, Mexico, 91020
    - Centro De Especialidades Medicas Del Estado De Veracruz
Netherlands
- - Alkmaar, Netherlands, 1815 JD
    - Noordwest Ziekenhuisgroep
  - Almere, Netherlands, 1311 RL
    - EB FlevoResearch
  - Amersfoort, Netherlands, 3813 TZ
    - Meander Medisch Centrum
  - Amersfoort, Netherlands, 3813 TZ
    - Meander Medical Center
  - Amstelveen, Netherlands, 1186 AM
    - Amstelland Hospital
  - Amsterdam, Netherlands, 1105 AZ
    - Academic Medical Center
  - Amsterdam, Netherlands, 1081 HV
    - VU University Medical Center
  - Amsterdam, Netherlands, 1091 AC
    - Onze Lieve Vrouwe Gasthuis
  - Amsterdam, Netherlands, 1034 CS
    - BovenIJ Ziekenhuis
  - Amsterdam, Netherlands, 1061 AE
    - OLVG, locatie West
  - Apeldoorn, Netherlands, 7334 DZ
    - Gelre Hospitals
  - Beverwijk, Netherlands, 1942 LE
    - Rode Kruis Ziekenhuis
  - Blaricum, Netherlands, 1261 AN
    - Tergooi Ziekenhuis
  - Breda, Netherlands, 4818 CK
    - Amphia Ziekenhuis
  - Breda, Netherlands, 4811 SW
    - Andro Medical Research B.V.
  - Delft, Netherlands, 2625 AD
    - Reinier de Graaf Ziekenhuis
  - Den Haag, Netherlands, 2545 CH
    - HagaZiekenhuis
  - Den Haag, Netherlands, 2526 HW
    - Hedramed
  - Den Haag, Netherlands, 2597 AX
    - Bronovo Ziekenhuis
  - Deventer, Netherlands, 7416SE
    - Deventer Ziekenhuis
  - Dirksland, Netherlands, 3247 BW
    - Van Weel Bethesda Hospital
  - Doetinchem, Netherlands, 7009 BL
    - Slingeland Ziekenhuis
  - Dordrecht, Netherlands, 3318 AT
    - Albert Schweitzer Ziekenhuis-Albert Schweitzer Hospital
  - Ede, Netherlands, 6716 RP
    - Ziekenhuis Gelderse Vallei
  - Eindhoven, Netherlands, 5611 NV
    - Andromed Eindhoven
  - Eindhoven, Netherlands, 5623 EJ
    - Heartcentre Catharina Hospital
  - Enschede, Netherlands, 7512 KZ
    - Medisch Spectrum Twente
  - Gorinchem, Netherlands, 4204 AA
    - Beatrix Ziekenhuis
  - Gorinchem, Netherlands, 4204 AA
    - Beatrix Hospital
  - Gouda, Netherlands, 2803 HH
    - Groene Hart Ziekenhuis
  - Groningen, Netherlands, 9713 GZ
    - University Medical Center Groningen
  - Groningen, Netherlands, 9728 NT
    - Martini Ziekenhuis
  - Haarlem, Netherlands, 2035 RC
    - Spaarne Gasthuis
  - Hardenberg, Netherlands, 7772 SE
    - Ropcke Zweers Hospital
  - Harderwijk, Netherlands, 3844 DG
    - St. Jansdal Ziekenhuis
  - Heerlen, Netherlands, 6419 PC
    - Zuyderland Medisch Centrum
  - Heerlen, Netherlands, 6419PC
    - Zuyderland
  - Hoogeveen, Netherlands, 7909 AA
    - Treant Zorggroep, location Bethesda
  - Hoorn, Netherlands, 1624 NP
    - Vascular Research Centre
  - Kloosterhaar, Netherlands, 7694 AC
    - Quality Care Research
  - Leeuwarden, Netherlands, 8934 AD
    - Medisch Centrum Leeuwarden
  - Leiden, Netherlands, 2333 ZA
    - Leiden University Medical Center
  - Leiden, Netherlands, 2334 CK
    - Alrijne Ziekenhuis
  - Leiderdorp, Netherlands, 2353 GA
    - Alrijne Ziekenhuis
  - Maarssen, Netherlands, 3607 KN
    - GCM Maarssenbroek
  - Maastricht, Netherlands, 6229 HX
    - Maastricht University Medical Center
  - Meppel, Netherlands, 7943 KA
    - Isala Diaconessenhuis
  - Nieuwegein, Netherlands, 3435 CM
    - St Antonius hospital
  - Nijmegen, Netherlands, 6532 SZ
    - Canisius Wilhelmina Ziekenhuis
  - Nijmegen, Netherlands, 6525 GA
    - Radboud University Nijmegen Medical Centre
  - Purmerend, Netherlands, 1441 RN
    - Waterland Hospital
  - Rotterdam, Netherlands, 3039 BD
    - Rotterdam Research Institute
  - Rotterdam, Netherlands, 3021 HC
    - Andro Medical Research B.V.
  - Rotterdam, Netherlands, 3037 AN
    - Hedramed
  - Rotterdam, Netherlands, 3083AN
    - Ikazia Ziekenhuis
  - Sneek, Netherlands, 8601 ZR
    - D&A Research and Genetics
  - Tiel, Netherlands, 4002 WP
    - Ziekenhuis Rivierenland
  - Tilburg, Netherlands, 5022 GC
    - St. Elisabeth Ziekenhuis
  - Tilburg, Netherlands, 5022 GC
    - Elisabeth-TweeSteden Ziekenhuis (previously named St. Elisabeth Ziekenhuis)
  - Tilburg, Netherlands, 5042 AD
    - Elisabeth TweeSteden Ziekenhuis (ETZ)
  - Uden, Netherlands, 5406 PT
    - Bernhoven Ziekenhuis
  - Utrecht, Netherlands, 3584 CX
    - University Medical Center Utrecht
  - Utrecht, Netherlands, 3511 NH
    - EB Utrecht
  - Utrecht, Netherlands, 3584 CX
    - Universitair Medisch Centrum (UMC) Utrecht - Locatie AZU
  - Veldhoven, Netherlands, 5504 DB
    - Maxima Medisch Centrum
  - Venlo, Netherlands, 5912 BL
    - VieCuri Medisch Centrum
  - Waalwijk, Netherlands, 5141 BM
    - Twee Steden Ziekenhuis
  - Zoetermeer, Netherlands, 2712 AB
    - Klinisch Onderzoek Praktijk Zoetermeer
  - Zwijndrecht, Netherlands, 3331 LZ
    - Albert Schweitzer Hospital
- Friesland
  - Heerenveen, Friesland, Netherlands, 8441 PW
    - Tjongerschans Ziekenhuis
- Limburg
  - Sittard-Geleen, Limburg, Netherlands, 6162 BG
    - Zuyderland MC
- Overijssel
  - Zwolle, Overijssel, Netherlands, 8025 AB
    - Isala
- Zuid-holland
  - Rotterdam, Zuid-holland, Netherlands, 3045 PM
    - St. Franciscus Gasthuis
  - Zoetermeer, Zuid-holland, Netherlands, 2725 NA
    - Het Lange Land Ziekenhuis
New Zealand
- - Auckland, New Zealand, 1023
    - Auckland City Hospital
  - Auckland, New Zealand, 1010
    - Optimal Clinical Trials
  - Auckland, New Zealand, 2025
    - Middlemore Clinical Trials
  - Auckland, New Zealand, 0622
    - North Shore Hospital, Laboratory
  - Auckland, New Zealand, 0622
    - North Shore Hospital- Inpatient Pharmacy
  - Christchurch, New Zealand, 8011
    - Lipid and Diabetes Research Group
  - Christchurch, New Zealand, 8041
    - Southern Clinical Trials Riccarton
  - Christchurch, New Zealand, 8011
    - Southern Clinical Trials Shirley Ltd Don Beavan Medical Research Centre
  - New Plymouth, New Zealand, 4310
    - Taranaki Base Hospital
  - Papamoa, New Zealand, 3118
    - Papamoa Pines Medical Centre
  - Rotorua, New Zealand, 3010
    - Rotorua Hospital
  - Tauranga, New Zealand, 3112
    - Clinical Horizons NZ Ltd
  - Tauranga, New Zealand, 3112
    - Clinical Trials Unit,Bay of Plenty(BOP) Clinical School
  - Wellington, New Zealand, 6021
    - Wellington Hospital
  - Wellington, New Zealand, 6021
    - CCDHB, Wellington Hospital, Clinical Measurement Unit
  - Wellington, New Zealand, 6242
    - Wellington Regional Hospital
- Auckland
  - Henderson, Auckland, New Zealand, 0612
    - Henderson Medical Centre
  - Takapuna, Auckland, New Zealand, 0622
    - North Shore Hospital
- Hastings
  - Frimley, Hastings, New Zealand, 4120
    - Hawke's Bay Hospital
Poland
- - Bialystok, Poland, 15-351
    - "OSTEO-MEDIC" s.c. Artur Racewicz, Jerzy Supronik
  - Bydgoszcz, Poland, 85-079
    - NZOZ Vitamed -Ga¿aj I Cichomski sp.j
  - Gdynia, Poland, 81-338
    - Medica Pro Familia Sp. z o.o. Spolka Komandytowo Akcyjna, Oddzial w Gdyni
  - Krakow, Poland, 30-053
    - Nzoz Gall-Med
  - Krakow, Poland, 31-567
    - NZOZ Centrum Zdrowia i Profilaktyki Dabie Sp. z.o.o.
  - Krakow, Poland, 31-501
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie,
  - Krakow, Poland, 31-501
    - Sp Zoz Szpital Uniwersytecki W Krakowie
  - Lodz, Poland, 90-368
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego
  - Lublin, Poland, 20-857
    - "TWOJA PRZYCHODNIA" Sp. Z o.o
  - Myslenice, Poland, 32-400
    - NeuroCor Banaszkiewicz, Kulaga, Ostrowska, Tomaszewski lekarze spolka partnerska
  - Opole, Poland, 45-706
    - Medicus w Opolu Sp z o. o.
  - Ostroda, Poland, 14-100
    - Specjalistyczny Osrodek Leczniczo-Badawczy Zbigniew Zegota
  - Oswiecim, Poland, 32-600
    - Medicome Sp. z o.o.
  - Poznan, Poland, 60-592
    - Centrum Zdrowia Metabolicznego Pawel Bogdanski
  - Ruda Slaska, Poland, 41-709
    - NZOZ Przychodnia Specjalistyczna Andrzej wittek Henryk Rudzki S.C.
  - Staszow, Poland, 28-200
    - KO-MED Centra Kliniczne Staszow
  - Warszawa, Poland, 01-192
    - Synexus Polska Sp. z o.o. Oddzial w Warszawie
  - Warszawa, Poland, 02-637
    - Instytut Kardiologii, Ii Klinika Choroby WieCowej
  - Warszawa, Poland, 04-628
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego
  - Warszawa, Poland, 04-628
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala
  - Wroclaw, Poland, 53-301
    - Dobrostan Michal Bogacki
- Dolnoslaskie
  - Jelenia Gora, Dolnoslaskie, Poland, 58-506
    - Jeleniogorskie Centrum Chorob Serca, Przychodnia Kardiologiczna, Poradnia Kardiologiczna
  - Wroclaw, Dolnoslaskie, Poland, 51-314
    - Zdrowie S.C. Agnieszka I Donald Drożdż
  - Wroclaw, Dolnoslaskie, Poland, 50-088
    - Synexus Polska Sp. z o.o. Oddzial we Wroclawiu
  - Wroclaw, Dolnoslaskie, Poland, 51-124
    - Wojewodzki Szpital Specjalistyczny we Wroclawiu, Osrodek Badawczo-Rozwojowy
  - Zarow, Dolnoslaskie, Poland, 58-130
    - Halina Serafin NZOZ Centrum Medyczne SERAFIN-MED
- Iodzkie
  - Lodz, Iodzkie, Poland, 92-213
    - SPZOZ Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej Uniwersytetu Medycznego
- Kujawsko-pomorskie
  - Bydgoszcz, Kujawsko-pomorskie, Poland, 85-079
    - NZOZ Vitamed
  - Bydgoszcz, Kujawsko-pomorskie, Poland, 85-231
    - NZOZ Centrum Medyczne KERmed
  - Grudziadz, Kujawsko-pomorskie, Poland, 86-300
    - Specjalistyczna Praktyka Lekarska Piotr Kubalski
  - Wloclawek, Kujawsko-pomorskie, Poland, 87-800
    - Specjalistyczne Gabinety Lekarskie "Medicor Plus" - Jerzy Kopaczewski
- Lodzkie
  - Lodz, Lodzkie, Poland, 90-132
    - Gabinet Lekarski Malgorzata Saryusz-Wolska
  - Lodz, Lodzkie, Poland, 91-490
    - "Prywatny Gabinet Kardiologiczny" Dr N.Med. Maciej Kosmider
  - Lodz, Lodzkie, Poland, 90-368
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego sp. z o.o.
  - Piotrkow Trybunalski, Lodzkie, Poland, 97-300
    - Prywatny Gabinet Lekarski Dr n. med. Michal Ogorek
  - Skierniewice, Lodzkie, Poland, 96-100
    - Centrum Medyczne Ogrodowa sp. z o.o.
- Lubelskie
  - Lublin, Lubelskie, Poland, 20-045
    - Clinical Best Solutions
  - Lublin, Lubelskie, Poland, 20-091
    - Optimamed Specjalistyczne Gabinety Lekarskie
  - Lublin, Lubelskie, Poland, 20-362
    - KO-MED Centra Kliniczne Lublin II
  - Pulawy, Lubelskie, Poland, 24-100
    - KO-MED Centra Kliniczne Pulawy
  - Zamosc, Lubelskie, Poland, 22-400
    - KO-MED Centra Kliniczne Zamosc
- Malopolskie
  - Krakow, Malopolskie, Poland, 30-015
    - Landa Specjalistyczne Gabinety Lekarskie
  - Krakow, Malopolskie, Poland, 31-121
    - Szpital Specjalistyczny im. J. Dietla w Krakowie, Oddzial Kardiologii
  - Krakow, Malopolskie, Poland, 31-216
    - Centrum Medyczne Zdrowa J. Trebacz, W. Zajdel Spolka Jawna
  - Krakow, Malopolskie, Poland, 31-315
    - Centrum Medyczne A-Z Clinic
  - Krakow, Malopolskie, Poland, 31-501
    - Krakowskie Centrum Medyczne Sp. z o.o.
  - Krakow, Malopolskie, Poland, 31-202
    - Krakowski Szpital Specjalistyczny im. Jana Pawla II, Oddzial Szybkiej Diagnostyki
  - Krakow, Malopolskie, Poland, 31-531
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie,
  - Myslenice, Malopolskie, Poland, 32-400
    - NeuroCor Banaszkiewicz, Kulaga, Ostrowska, Tomaszewski lekarze spolka partnerska
  - Nowy Targ, Malopolskie, Poland, 34-400
    - INTERCARD Sp. z. o. o. Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii w Nowym Targu
  - Tarnow, Malopolskie, Poland, 33-100
    - Centrum Szybkiej Diagnostyki Kardiologicznej Kardiomed M. Zabowka E. Zabowka
  - Tarnow, Malopolskie, Poland, 33-100
    - Specjalistyczny Gabinet Lekarski Internistyczno-Kardiologiczny Boguslaw Derlaga
- Mazowieckie
  - Katowice, Mazowieckie, Poland, 40-040
    - Synexus Polska Sp. z o.o. Oddzial w Katowicach
  - Plock, Mazowieckie, Poland, 09-402
    - Niepubliczny Zaklad Opieki Zdrowotnej Specjalistyczna Przychodnia Lekarska "MEDIKARD"
  - Warszawa, Mazowieckie, Poland, 04-730
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego sp. z o.o.
  - Warszawa, Mazowieckie, Poland, 01-875
    - Centrum Medyczne Piaski Filia Nr 9
  - Warszawa, Mazowieckie, Poland, 02-507
    - Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych W Warszawie
  - Warszawa, Mazowieckie, Poland, 02-507
    - CSK MSW w Warszawie, Klinika Kardiologii Zachowawczej i Nadcisnienia Tetniczego
  - Warszawa, Mazowieckie, Poland, 04-141
    - Wojskowy Instytut Medyczny, Klinika Kardiologii i Chorob Wewnetrznych, Centralny Szpital Kliniczny
  - Warszawa, Mazowieckie, Poland, 04-628
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego
- Podkarpackie
  - Brzozow, Podkarpackie, Poland, 36-200
    - Szpital Specjalistyczny w Brzozowie, Podkarpacki Osrodek Onkologiczny im. Ks. B. Markiewicza Oddzial
  - Krosno, Podkarpackie, Poland, 38400
    - INTERCARD Sp. z o.o. Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii w Krosnie
  - Rzeszow, Podkarpackie, Poland, 35205
    - EMED Centrum Uslug Medycznych Ewa Smialek
- Podlaskie
  - Bialystok, Podlaskie, Poland, 15-875
    - Podlaski Osrodek Kardiologii Janusz Korecki
  - Bialystok, Podlaskie, Poland, 15-351
    - """OSTEO-MEDIC"" s.c. Artur Racewicz, Jerzy Supronik"
- Pomorskie
  - Gdansk, Pomorskie, Poland, 80-382
    - Synexus Polska Sp. z o.o. Oddzial w Gdansku
  - Gdansk, Pomorskie, Poland, 80-542
    - Niepubliczny Zaklad Opieki Zdrowotnej Gdanskie Centrum Zdrowia, Poradnia Kardiologiczna
  - Gdansk, Pomorskie, Poland, 80-546
    - Centrum Badan Klinicznych Pi-House, Poradnia Diabetologiczna
  - Gdynia, Pomorskie, Poland, 81-384
    - Synexus Polska Sp. z o.o. Oddzial w Gdyni
  - Gdynia, Pomorskie, Poland, 81-423
    - NZOZ "PRO CORDIS" Sopockie Centrum Badan Kardiologicznych
  - Gdynia, Pomorskie, Poland, 81-472
    - Gabinet Kardiologiczno - lnternistyczny
  - Sopot, Pomorskie, Poland, 81-756
    - Centrum Medyczne "SOPMED" Sp. z o.o.
  - Starogard Gdanski, Pomorskie, Poland, 83-200
    - Indywidualna Specjalistyczna Praktyka Lekarska Malgorzata Biedrzycka
- Slaskie
  - Bytom, Slaskie, Poland, 41-902
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Wojewodzki Szpital Specjalistyczny Nr 4 w Bytomiu,
  - Katowice, Slaskie, Poland, 40-083
    - Bogna Gabrylewicz Andrzej Ochala Unimed s.c.
  - Katowice, Slaskie, Poland, 40-648
    - Pro Familia Altera Poradnia Wielospecjalistyczna
  - Katowice, Slaskie, Poland, 40-752
    - NZOZ Terapia Optima
  - Ruda Slaska, Slaskie, Poland, 41-709
    - Przychodnia Specjalistyczna Samodzielny Publiczny ZOZ w Rudzie Slaskiej, Poradnie Specjalistyczne,
  - Wola, Slaskie, Poland, 43-225
    - NZOZ "Medyk"Sp. z o. o.
- Swietokrzyskie
  - Kielce, Swietokrzyskie, Poland, 25-315
    - Prywatny Gabinet Lekarski Marianna Janion
- Warminsko-mazurskie
  - Elblag, Warminsko-mazurskie, Poland, 82-300
    - Wojewodzki Szpital Zespolony w Elblagu, Oddzial Kardiologiczny z Pododdzialem Kardiologii Inwazyjnej
- Wielkopolskie
  - Poznan, Wielkopolskie, Poland, 60-702
    - Synexus Polska Sp. z o.o Oddzial w Poznaniu
  - Poznan, Wielkopolskie, Poland, 61-006
    - Nzoz "Twoja Przychodnia"
Puerto Rico
- - Anasco, Puerto Rico, 00610
    - The Office of Roberto J. Ayala-Rios, MD - Research Center and Private Practice (DMRA LLC)
  - Ponce, Puerto Rico, 00717
    - Cardiometabolic Research Center, Inc.
  - Ponce, Puerto Rico, 00717
    - Endocrine Lipid Diabetes Research Institute
  - San Juan, Puerto Rico, 00917
    - Pradnet Inc.
  - San Juan, Puerto Rico, 00920
    - Altamira Family Medicine And Research Institute
  - San Juan, Puerto Rico, 00926-2832
    - Miguel Sosa-Padilla, MD-Private Practice
  - San Juan, Puerto Rico, 00935
    - Centro de Diabetes para Puerto Rico
Romania
- - Baia Mare, Romania, 430032
    - Euromedica Hospital
  - Braila, Romania, 810249
    - Spitalul Clinic Judetean De Urgenta Braila(Braila County Clincal Emergency Hospital)
  - Brasov, Romania, 500209
    - S.C. Polimed Dacia S.R.L.
  - Brasov, Romania, 500283
    - Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL, Medicina Interna
  - Bucharest, Romania, 010192
    - Data Plus Medical Clinic
  - Bucharest, Romania, 020045
    - "Prof. Dr. N.C. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases,
  - Bucharest, Romania, 061118
    - Med Plus SRL (Med Plus Ltd.)
  - Bucharest, Romania, 20614
    - S.C. Centrul Medical "Sanatatea Ta" S.R.L.
  - Bucharest, Romania, 61118
    - Med Plus Srl
  - Bucuresti, Romania, 010825
    - Spitalul Universitar De Urgenta Militar Central, Dr. Carol Davila
  - Bucuresti, Romania, 020125
    - Spitalul Clinic Colentina, Departament Cardiologie
  - Bucuresti, Romania, 021967
    - SC Centrul Medical Policlinico Di Monza SRL, Cardiologie
  - Bucuresti, Romania, 030463
    - SC Policlinica CCBR SRL
  - Cluj-Napoca, Romania, 400006
    - Spitalul Clinic Judetean De Urgenta Cluj-Napoca, Diabet Zabarat
  - Cluj-Napoca, Romania, 400006
    - Spitalul Clinic Judetean de Urgenta Cluj-Napoca, Diabet Zaharat, Nutritie si Boli Metabolice
  - Galati, Romania, 800098
    - Dr. Mistodie Cristina Victoria MD, Office of
  - Galati, Romania, 800291
    - S.C. Diamed Obesity S.R.L.
  - Satu Mare, Romania, 440055
    - County Emergency Hospital Satu Mare Diabetes, Nutrition And Metabolic Diseases Department
  - Sibiu, Romania, 550245
    - County Clinical Emergency Hospital Sibiu
  - Tg. Mures, Romania, 540124
    - Cardio Med SRL, Cardiologie
  - Timisoara, Romania, 300125
    - Centrul Medical Sf. Stefan
  - Timisoara, Romania, 300125
    - Institution Centrul Medical Sf. Stefan SRL, Diabet Nutritie si Boli Metabolice
- Arges
  - Pitesti, Arges, Romania, 110084
    - Pitesti-Arges County Emergency Hospital
- Bihor
  - Oradea, Bihor, Romania, 410032
    - Medical Practice SRL
  - Oradea, Bihor, Romania, 410169
    - County Clinical Emergency Hospital Oradea
- Hunedoara
  - Deva, Hunedoara, Romania, 330084
    - County Emergency Hospital Deva
- JUD Maramures
  - Baia Mare, JUD Maramures, Romania, 430123
    - CMI Pop Calin Florin
- Judet Timis
  - Timisoara, Judet Timis, Romania, 300456
    - Centrul Medical Dr. Negrisanu SRL, Diabet Zaharat Nutritie si Boli Metabolice
- Maramures
  - Baia Mare, Maramures, Romania, 430130
    - Dr. Pop Calin Florin - Cabinet Cardiologie
- Mures
  - Targu Mures, Mures, Romania, 540143
    - Podoleanu G. Cristian-Gheorghe-Calin - Cardiology Medical Practice
- Prahova
  - Ploiesti, Prahova, Romania, 100163
    - Diabmed Dr. Popescu Alexandrina SRL, Diabet, Nutritie, Boli Metabolice
  - Ploiesti, Prahova, Romania, 100342
    - Dr. Busegeanu Mihaela Private Practice
- Sectorul 2
  - Bucharest, Sectorul 2, Romania, 021611
    - Clinica Medicala Synexus Ltd.
- Timis
  - Timisoara, Timis, Romania, 300310
    - Institute of Cardiovascular Diseases Timisoara
Russian Federation
- - Chelyabinsk, Russian Federation, 454047
    - Municipal Budgetary State Healthcare Institution "City Clinical Hospital #6"
  - Chelyabinsk, Russian Federation, 454092
    - Non-State Institution of Healthcare
  - Chelyabinsk, Russian Federation, 454136
    - State Budgetary Healthcare Institution ¿Region Clinical Hospital #3¿
  - Ekaterinburg, Russian Federation, 620039
    - Municipal Autonomous Institution "City Clinical Hospital #14"
  - Ivanovo, Russian Federation, 153012
    - Regional Budgetary Healthcare Institution "Cardiology Dispensary"
  - Kaluga, Russian Federation, 428007
    - State Budgetary Institution of Healthcare of Kaluga Region "Kaluga Regional Hospital"
  - Kazan, Russian Federation, 420012
    - Federal State Budgetary Educational Institution of Higher Education "Kazan State Medical University"
  - Kazan, Russian Federation, 420064
    - State Autonomous Healthcare Institution "Republic Clinical Hospital"
  - Kemerovo, Russian Federation, 650000
    - "SAHI of Kemerovo ""Regional Clinical Hospital of Emergency Medical Care n.a. M.A Podgorbunsky """
  - Kemerovo, Russian Federation, 650000
    - Municipal Budgetary Institution of Healthcare Municipal Clinical Hospital #3 n.a. M.A. Podgorbunsky
  - Kemerovo, Russian Federation, 650002
    - FSBI "Research institute of complex problems of cardio-vascular diseases" of
  - Kemerovo, Russian Federation, 650099
    - FSHI "Medical and Sanitary Unit of the Ministry of Internal Affairs of Russia across
  - Kirov, Russian Federation, 610014
    - Kirov Regional State Budgetary Healthcare Institution "Kirov City Clinical Hospital #1"
  - Kursk, Russian Federation, 305035
    - Regional Budgetary Healthcare Institution "Kursk City Clinical Emergency Hospital"
  - Moscow, Russian Federation, 109388
    - Non-State Institution of Healthcare "Central Clinical Hospital #6 OAO "RZhD"
  - Moscow, Russian Federation, 121359
    - Federal State Budgetary Institution "Central Clinical Hospital with Polyclinic"
  - Moscow, Russian Federation, 125284
    - Moscow State Healthcare Institution "City clinical hospital n.a. S.P.Botkin"
  - Moscow, Russian Federation, 111539
    - SBHI Moscow city "City Clinical Hospital #15 n.a. O.M. Filatova" of Moscow Healthcare Department
  - Moscow, Russian Federation, 121552
    - "Federal State Budgetary Institution "Russian Cardiology Research And Production Complex" Of
  - Moscow, Russian Federation, 127644
    - State Budget Institution of Healthcare (SBIH) of Moscow "City Clinical Hospital #81
  - Moscow, Russian Federation, 129090
    - Federal State Budget Institution "Out-patient Clinic #3" of Russian Federation, President's
  - Murmansk, Russian Federation, 183047
    - State Regional Budgetary Healthcare Institution
  - Nizhniy Novgorod, Russian Federation, 603076
    - State Budgetary Healthcare Institution of Nizhegorodskaya Region
  - Novosibirsk, Russian Federation, 630099
    - "Reafan" LLC
  - Novosibirsk, Russian Federation, 630102
    - Municipal Budgetary Institution of Healthcare of Novosibirsk
  - Novosibirsk, Russian Federation, 630102
    - State Budgetary Institution of Healthcare of Novosibirsk region City Clinical Hospital of Emergency
  - Novosibirsk, Russian Federation, 630089
    - Federal State Budgetary Institution "Research Institute of Therapy and Preventive Medicine"
  - Penza, Russian Federation, 440026
    - State Budgetary Healthcare Institution (SBHI) N.N. Burdenko Regional Clinical Hospital of Penza
  - Pushkin, Russian Federation, 196601
    - SBHI of Saint-Petersburg "City Hospital # 38 n.a. N.A. Semashko"
  - Rostov-on-Don, Russian Federation, 344022
    - State Budgetary Educational Institution of Higher Professional Education
  - Rostov-on-Don, Russian Federation, 344068
    - State Budgetary Educational Institution of Higher Professional Education
  - Ryazan, Russian Federation, 390039
    - State Budgetary Institution "Ryazan Regional Clinical Hospital"
  - Saint Petersburg, Russian Federation, 194354
    - Limited Liability Company "Reavita"
  - Saint Petersburg, Russian Federation, 196084
    - LLC "Institution of medical studies"
  - Saint Petersburg, Russian Federation, 197341
    - Federal State Budgetary Institution "Federal Almazov Medical Research Centre" of
  - Saint-Petersberg, Russian Federation, 191186
    - Limited Liability Company International Medical Centre SOGAZ
  - Saint-Petersburg, Russian Federation, 192148
    - Saint-Petersburg State Budgetary Institution of Healthcare "City Hospital #23"
  - Saint-Petersburg, Russian Federation, 193312
    - Saint-Petersburg State Budgetary Healthcare Institution "City Alexandrovskaya Hospital"
  - Saint-Petersburg, Russian Federation, 197022
    - SBEI of HPE "First Pavlov State Medical University of St. Petersburg" of the MoH of the RF
  - Saint-Petersburg, Russian Federation, 197110
    - Federal State Budgetary Institution "Advisory Diagnostic Center and Polyclinic"
  - Saint-Petersburg, Russian Federation, 198205
    - Saint-Petersburg State Budgetary Healthcare Institution "City Hospital #15"
  - Saint-Petersburg, Russian Federation, 196247
    - Saint-Petersburg State Budgetary Institution of Healthcare "City Hospital #26"
  - Samara, Russian Federation, 443070
    - State Budgetary Healthcare Institution "Samara Regional Clinical Cardiology Dispensary"
  - Saratov, Russian Federation, 410053
    - State Institution of Healthcare "Regional Clinical Hospital"
  - Saratov, Russian Federation, 410039
    - MHI "City Clinical Hospital 12"of the Healthcare Committee of
  - St. Petersburg, Russian Federation, 197022
    - Federal State Budgetary Educational Institution of Higher Education "Academician I.P. Pavlov First
  - Tomsk, Russian Federation, 634009
    - Tyumen Cardiology Research Center-branch of the Tomsk NRMC
  - Tomsk, Russian Federation, 634050
    - State Budgetary Educational Institution of Highest Professional Education
  - Tyumen, Russian Federation, 625000
    - State Autonomous Healthcare Institution of Tyumen region "Scientific-Practical Medical Center"
  - Tyumen, Russian Federation, 625026
    - "Tyumen Cardiology Center" Affiliate of the FSBSI "Scientific and Research Institution of Cardiology
  - Yaroslavl, Russian Federation, 150003
    - State Autonomous Healthcare Institution Of Yaroslavl Region
  - Yaroslavl, Russian Federation, 150023
    - State Budgetary Healthcare Institution of Yaroslavl Region "Clinical Hospital No. 10"
  - Yaroslavl, Russian Federation, 150030
    - State Healthcare Institution of Yaroslavl Region "Clinical Hospital #8"
  - Yaroslavl, Russian Federation, 150003
    - State Autonomous Healthcare Institution of Yaroslavl region Clinical Emergency Hospital n.a..N.V.So
  - Yaroslavl, Russian Federation, 150010
    - FSBEI of HE "Yaroslavl State Medical University" MH of the Russian Federation based on Clinical
- Krasnodar Region
  - Krasnodar, Krasnodar Region, Russian Federation, 350086
    - State Budgetary Healthcare Institution "Research Institution - Regional Clinical Hospital #1
- Moscow Region
  - Lubertsy, Moscow Region, Russian Federation, 140006
    - State Budgetary Healthcare Institution of Moscow Region "Lubertsy Regional Hospital #2"
  - Troitsk, Moscow Region, Russian Federation, 142190
    - Federal State Budgetary Institution of Healthcare Hospital of Russian Academy of Sciences
- Sankt-peterburg
  - St. Petersburg, Sankt-peterburg, Russian Federation, 197022
    - 1st Pavlov State Medical University of St. Petersburg
- Sestroretsk
  - St. Petersburg, Sestroretsk, Russian Federation, 197706
    - Saint Petersburg State Budgetary Institution of Healthcare
- Tatarstan Republic
  - Kazan, Tatarstan Republic, Russian Federation, 420033
    - FSBEI of HE Kazan State Medical University on the base of SBHI Clinical Hospital No.2
Slovakia
- - Banska Bystrica, Slovakia, 974 01
    - Stredoslovensky ustav srdcovych a cievnych chorob a.s.
  - Banska Bystrica, Slovakia, 97517
    - Fakultna nemocnica F. D. Roosevelta
  - Bardejov, Slovakia, 08501
    - Alian s.r.o., kardiologicka ambulancia
  - Bratislava, Slovakia, 81369
    - Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto, l.interna klinika
  - Bratislava, Slovakia, 81369
    - Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto
  - Bratislava, Slovakia, 826 06
    - UN Bratislava, Nemocnica Ruzinov, V. interna klinika LFUK a UN Bratislava
  - Bratislava, Slovakia, 83101
    - Kardiovaskularne Centrum S.R.O.
  - Bratislava, Slovakia, 83101
    - Metabolicke centrum MUDr. Katariny Raslovej, s.r.o.
  - Bratislava, Slovakia, 833 48
    - Narodny ustav srdcovych a cievnych chorob, a.s.
  - Bratislava, Slovakia, 83305
    - Univerzitna nemocnica Bratislava
  - Bratislava, Slovakia, 83348
    - Narodny ustav srdcovych a cievnych chorob, a.s.
  - Bratislava, Slovakia, 85101
    - VERIA, s.r.o. -Kardiologicka ambulancia
  - Bratislava, Slovakia, 811 08
    - Metabol KLINIK s.r.o., Ambulancia pre diabetologiu, poruchy latkovej premeny a vyzivy
  - Bratislava, Slovakia, 81369
    - Univerzitna nemocnica Bmtislava, Nemocnica Stare Mesto
  - Bratislava, Slovakia, 841 08
    - KARDIO-SANUS spol.,s.r.o.,Kardiologicka, interna a sonograficka ambulancia
  - Bratislava, Slovakia, 84107
    - KARDIO-SANUS spol. s.r.o.
  - Bratislava, Slovakia, 85107
    - UN Bratislava Nemocnica Sv.Cyrila a Metoda, kardiologicka ambulancia 1
  - Dolny Kubin, Slovakia, 02601
    - Endiamed s.r.o. Nestatna diabetologicka a endokrinologicka ambulancia
  - Dolny Kubin, Slovakia, 02601
    - JM-Interna s.r.o., interna ambulancia
  - Kosice, Slovakia, 04011
    - AGTO., spol. s r. o.
  - Kosice, Slovakia, 04022
    - Cardio D&R spol.s.r.o., kardiologicka ambulancia
  - Kosice, Slovakia, 040 01
    - CARDIO D&R s.r.o., Kardiologicka ambulancia
  - Kralovsky Chlmec, Slovakia, 077 01
    - Medicentrum Heart, Spol. S.R.O
  - Levice, Slovakia, 93405
    - CELL-B s.r.o. interna ambulancia
  - Liptovsky Mikulas, Slovakia, 031 23
    - Liptovska nemocnica s poliklinikou MUDr.Ivana Stodolu Liptovsky Mikulas
  - Lubochna, Slovakia, 034 91
    - Narodny Endokrinologicky A Diabetologicky Ustav N.O.
  - Lucenec, Slovakia, 984 39
    - Kardio 1 S.R.O.
  - Martin, Slovakia, 036 59
    - Klinika hematologie a transfuziologie, Univerzitna nemocnica Martin
  - Moldava nad Bodvou, Slovakia, 045 01
    - MEDI M&M s.r.o., Ambulancia vnutorneho lekarstva
  - Namestovo, Slovakia, 02901
    - MUDr. Kanderkova s.r.o., Diabetologicka ambulancia
  - Nitra, Slovakia, 94901
    - Kardiocentrum Nitra s.r.o., kardiologicka ambulancia
  - Nove Zamky, Slovakia, 940 34
    - Fakultna nemocnica s poliklinikou Nove Zamky, I. interna klinika
  - Pezinok, Slovakia, 90201
    - Mediab s.r.o. Diabetologicka ambulancia
  - Piestany, Slovakia, 921 01
    - BENIMED s.r.o.
  - Presov, Slovakia, 08001
    - MEDISPOL s.r.o.
  - Rimavska Sobota, Slovakia, 979 01
    - Medilex s.r.o. Interna ambulancia
  - Rimavska Sobota, Slovakia, 97901
    - Kardioamb S.R.O.
  - Trencin, Slovakia, 911 01
    - DIAMEL, s.r.o., Diabetologicka ambulancia
  - Trnava, Slovakia, 917 01
    - BV Medical, s.r.o. Diabetologicka ambulancia,
  - Trnava, Slovakia, 917 01
    - Kardiologická ambulancia
  - Zilina, Slovakia, 01001
    - Medivasa s.r.o., Diabetologicka ambulancia
- Bratislavsky
  - Bratislava, Bratislavsky, Slovakia, 826 06
    - Nemocnica Ruzinov-Univerzitna Nemocnica Bratislava (UNB)
South Africa
- - Centurion, South Africa, 0157
    - Unitas Hospital.
  - Gauteng, South Africa, 1619
    - Clinresco Centres (Pty) Ltd-Central Professional Suits
  - Paarl, South Africa, 7646
    - Paarl Research Centre
  - Parow, South Africa, 7500
    - TREAD Research CC
  - Worcester, South Africa, 6850
    - Clinical Projects Research SA (PTY) LTD
- FREE State
  - Bloemfontein, FREE State, South Africa, 9301
    - Josha Research
  - Bloemfontein, FREE State, South Africa, 9301
    - Iatros International
  - Welkom, FREE State, South Africa, 9460
    - Welkom Clinical Trial Centre
- Gauteng
  - Halfway House, Gauteng, South Africa, 1685
    - Midrand Medical Centre
  - Houghton, Gauteng, South Africa, 2198
    - Centre for Diabetes and Endocrinology
  - Johannesburg, Gauteng, South Africa, 2157
    - Sunninghill Hospital
  - Lyttelton, Gauteng, South Africa, 0157
    - I Engelbrecht Research (Pty) Ltd
  - Parktown, Gauteng, South Africa, 2193
    - Charlotte Maxeke Johannesburg Academic Hospital
  - Pretoria, Gauteng, South Africa, 0184
    - Synexus Watermeyer Clinical Research Centre
  - Pretoria, Gauteng, South Africa, 0158
    - Medipark Centre for Clinical Research
  - Pretoria West, Gauteng, South Africa, 0183
    - Jongaie Research
  - Roodepoort, Gauteng, South Africa, 1724
    - Roodepoort Medicross Clinical Research Centre
  - Soweto, Gauteng, South Africa, 2013
    - Wits Clinical Research-Chris Hani Baragwanath Hospital
  - Sunnyside, Gauteng, South Africa, 0083
    - Medi-Clinic Heart Hospital
- KWA ZULU Natal
  - Merebank, Durban, KWA ZULU Natal, South Africa, 4052
    - Nash Ranjith Research Centre
- Kwazulu-natal
  - Durban, Kwazulu-natal, South Africa, 4001
    - Suite 502
  - Durban, Kwazulu-natal, South Africa, 4091
    - Dr Ganesh c/o Dr NB Maharaj
- Limpopo
  - Thabazimbi, Limpopo, South Africa, 0380
    - Limpopo Clinical Research Initiative
- Mpumalanga
  - Moloto, Mpumalanga, South Africa, 1022
    - Zinakekele Medical Centre
  - Witbank (eMalahleni), Mpumalanga, South Africa, 1035
    - Drs Joynt Venter & Associates
- Western CAPE
  - Cape Town, Western CAPE, South Africa, 7530
    - Tiervlei Trial Centre
  - Cape Town, Western CAPE, South Africa, 7130
    - Dr JM Engelbrecht Trial Site-Vergelegen Mediclinic
  - Cape Town, Western CAPE, South Africa, 7700
    - Synopsis Research cc
  - Somerset West, Western CAPE, South Africa, 7130
    - Helderberg Research Institute
  - Somerset West, Western CAPE, South Africa, 7130
    - Synexus Helderberg Clinical Research Centre
  - Somerset West, Western CAPE, South Africa, 7130
    - Vergelegen Mediclinic-Helderberg Research Institute
Spain
- - A Coruna, Spain, 15006
    - Gerencia de Gestion integrada de A Coruna
  - Albacete, Spain, 02006
    - Complejo Hospitalario Universitario de Albacete
  - Alicante, Spain, 03010
    - Hospital General Universitario de Alicante; Servicio Cardiologia
  - Almeria, Spain, 04120
    - Hospital Virgen del Mar
  - Barcelona, Spain, 08025
    - Hospital de La Santa Creu I Sant Pau
  - Barcelona, Spain, 08035
    - Hospital Universitari Vall d'Hebron
  - Barcelona, Spain, 08003
    - Parc de Salut Mar- Hospital del Mar
  - Barcelona, Spain, 08907
    - Hospital Universitario de Bellvitge
  - Barcelona, Spain, 08003
    - Parc de Salut mar ¿ Hospital del Mar
  - Barcelona, Spain, 08022
    - Centre Teknon
  - Barcelona, Spain, 08025
    - EAP Sardenya
  - Barcelona, Spain, 08540
    - CAP Centelles
  - Barcelona, Spain, 08923
    - Fundacio Hospital de I'Esperit Sant
  - Barcelona, Spain, 08902
    - CAP Amadeu Torner
  - Cordoba, Spain, 14004
    - Hospital Universitario Reina Sofia
  - Ferrol, Spain, 15401
    - Complexo Hospitalario Universitario Arquitecto Marcide-Profesor Novoa Santos De Ferrol
  - Granada, Spain, 18012
    - Hospital Universitario San Cecilio
  - Granada, Spain, 18014
    - Hospital Universitario Virgen de las Nieves (HUVN)
  - Lleida, Spain, 25198
    - Hospital Universitari Arnau de Vilanova
  - Lleida, Spain, 25198
    - Hospital Universitari Arnau De Vilanova (Huav)
  - Lleida, Spain, 25198
    - Pharmacy - Hospital Universitari Arnau de Vilanova (HUAV)
  - Lugo, Spain, 27003
    - Hospital Universitario Lucus Augusti
  - Madrid, Spain, 28040
    - Fundacion Jimenez Diaz
  - Madrid, Spain, 28034
    - Hospital Universitario Ramon Y Cajal
  - Madrid, Spain, 28040
    - Hospital Universitario Fundacion Jimenez Diaz
  - Madrid, Spain, 28006
    - Hospital Universitario de La Princesa
  - Madrid, Spain, 28007
    - Hospital General Universitario Gregorio Maranon
  - Madrid, Spain, 28029
    - Hospital Carlos III
  - Madrid, Spain, 28046
    - Hospital Universitario La Paz; Unidad Metabolico-Vascular
  - Madrid, Spain, 28702
    - Hospital Universitario Infanta Sofía
  - Madrid, Spain, 28805
    - Carretera Alcala-Meco s/n
  - Madrid, Spain, 28805
    - H. U. Principe de Asturias
  - Malaga, Spain, 29010
    - Hospital Universitario Virgen de la Victoria
  - Malaga, Spain, 29009
    - Hospital Regional Universitario de Malaga
  - Malaga, Spain, 29006
    - Hospital Universitario Virgen de la Victoria. CE San Jose Obrero
  - Murcia, Spain, 30008
    - Hospital General Universitario Morales Meseguer
  - Reus (Tarragona), Spain, 43204
    - Hospital Universitario Sant Joan de Reus
  - Sevilla, Spain, 41009
    - Hospital Universitario Virgen Macarena
  - Sevilla, Spain, 41014
    - Hospital Universitario Virgen de Valme
  - Sevilla, Spain, 41003
    - Clínica Nuevas Tecnologías en Diabetes y Endocrinología
  - Tarragona, Spain, 43002
    - CAP Muralles
  - Valencia, Spain, 46014
    - Hospital General Universitario de Valencia
  - Zaragoza, Spain, 50009
    - Hospital Clinico Universitario Miguel Servet; Medicina Interna
- A Coruna
  - Santiago de Compostela, A Coruna, Spain, 15706
    - Hospital Clinico Universitario de Santiago de Compostela
- Alicante
  - Alcoy, Alicante, Spain, 03804
    - Hospital Virgen de los Lirios
- Andalucia
  - Malaga, Andalucia, Spain, 29010
    - Hospital Regional Universitario de Malaga
  - Sevilla, Andalucia, Spain, 41013
    - Hospital Universitario Virgen del Rocío
- Asturias
  - Oviedo, Asturias, Spain, 33006
    - Centro de Salud El Cristo
  - Oviedo, Asturias, Spain, 33009
    - Centro Salud Paulino Prieto
- Barcelona
  - L'Hospitalet de Llobregat, Barcelona, Spain, 08907
    - Hospital Universitari de Bellvitge
  - Sant Adria De Besos, Barcelona, Spain, 08930
    - CAP La Mina
  - Vic, Barcelona, Spain, 08500
    - EAP Vic
- Barcelona-cataluna
  - L'Hospitalet De Llobregat, Barcelona-cataluna, Spain, 08905
    - CAP Florida
- Barcelona/cataluna
  - El Prat De Llobregat, Barcelona/cataluna, Spain, 08820
    - CAP Disset De Setembre (Sant Cosme I Sant Damia)
- Cantabria
  - Santander, Cantabria, Spain, 39008
    - Hospital Universitario Marques de Valdecilla
- Catalonia
  - Tarragona, Catalonia, Spain, 43007
    - Hospital Universitari de Tarragona Joan XXIII
- Comunidad Valenciana
  - Alicante, Comunidad Valenciana, Spain, 03550
    - Hospital Universitario San Juan de Alicante
- Gerona
  - Peralada, Gerona, Spain, 17491
    - Albera Salut
- Girona
  - Salt, Girona, Girona, Spain, 17190
    - Hospital Santa Caterina
- Girona-catalonia
  - Figueres, Girona-catalonia, Spain, 17600
    - Hospital de Figueres
- Illes Balears
  - Inca, Illes Balears, Spain, 07300
    - Hospital Comarcal d'Inca
- LA Coruna
  - El Ferrol, LA Coruna, Spain, 15405
    - Hospital Arquitecto Marcide
- Madrid
  - Majadahonda, Madrid, Spain, 28222
    - Hospital Hospital Universitario Puerta de Hierro - Majadahonda
  - Pozuelo de Alarcon, Madrid, Spain, 28223
    - Hospital Universitario Quiron Madrid
- PAIS Vasco
  - Barakaldo, PAIS Vasco, Spain, 48903
    - Hospital Universitario de Cruces
- Tarragona
  - Reus, Tarragona, Spain, 43204
    - Hospital Universitario Sant Joan de Reus
- Valencia
  - Requena, Valencia, Spain, 46340
    - Hospital General de Requena
Sweden
- - Eksjö, Sweden, 57535
    - Kasernens Läkarservice AB
  - Goteborg, Sweden, 41345
    - Sahlgrenska Universitetssjukhuset
  - Helsingborg, Sweden, 252 20
    - Pharmasite AB
  - Kristianstad, Sweden, 291 85
    - Medicinklinikens forskningsenhet
  - Lund, Sweden, 222 22
    - Probar E Lund AB
  - Lund, Sweden, 222 21
    - Hjartmottagningen, Capio Citykliniken
  - Malmo, Sweden, 205 02
    - Karlkliniken, Skanes Universitetssjukhus i Malmo
  - Malmo, Sweden, 211 52
    - Pharmasite AB
  - Molndal, Sweden, 431 80
    - Forskningsenheten, Medicinmottagningen Sahlgrenska Universitetssjukhuset/Molndal, Hus J
  - Ostersund, Sweden, 83183
    - Ostersunds sjukhus
  - Rattvik, Sweden, 79530
    - Dalecarlia Clinical Research Center
  - Skelleftea, Sweden, 93186
    - Skellefteå lasarett
  - Stockholm, Sweden, 17176
    - Karolinska Universitetssjukhuset
  - Stockholm, Sweden, 111 57
    - A+Science City site
  - Stockholm, Sweden, 182 82
    - Hjartkliniken
  - Uppsala, Sweden, 75185
    - Akademiska Sjukhuset
  - Vasteras, Sweden, 721 89
    - Vastmanlands Sjukhus Vasteras
- Huddinge
  - Stockholm, Huddinge, Sweden, 141 86
    - Karolinska Universitetssjukhuset Huddinge
Switzerland
- - Lausanne, Switzerland, 1011
    - Centre Hospitalier Universitaire Vaudois
  - Lugano, Switzerland, CH-6900
    - Cardiocentro Ticino
  - Lugano, Switzerland, CH-6900
    - Fondazione Diabete Lugano
  - Luzern 16, Switzerland, CH-6000
    - Luzerner Kantonsspital Luzern
  - St. Gallen, Switzerland, CH-9007
    - Kantonsspital St. Gallen
- Basel
  - Reinach, Basel, Switzerland, 4153
    - Diagene Laboratories Inc.
- Basel Stadt
  - Basel, Basel Stadt, Switzerland, 4031
    - Universitätsspital
- Geneva
  - Geneve, Geneva, Switzerland, 1211
    - Hospitaux Universitaires de Geneve (HUG)
- Vaud
  - Lausanne, Vaud, Switzerland, 1011
    - Policlinique Medicale Universitaire
- Zurich
  - Winterthur, Zurich, Switzerland, 8401
    - Kantonsspital Winterthur
Taiwan
- - Kaohsiung, Taiwan, 807
    - Kaohsiung Medical University Chung-Ho Memorial Hospital - New
  - New Taipei City, Taiwan, 23148
    - Cardinal Tien Hospital
  - Taichung, Taiwan, 402
    - Chung Shan Medical University Hospital
  - Tainan, Taiwan, 70428
    - National Cheng Kung University (NCKU) Hospital
  - Taipei, Taiwan, 11217
    - Taipei Veterans General Hospital
  - Taipei, Taiwan, 10449
    - Mackay Memorial Hospital
  - Taipei, Taiwan, 10041
    - National Taiwan University Hospital
- Taiwan R O C
  - Taichung, Taiwan R O C, Taiwan, 40447
    - China Medical University Hospital
  - Taipei, Taiwan R O C, Taiwan, 10002
    - National Taiwan University Hospital
Thailand
- - Bangkok, Thailand, 10400
    - Cardiology Unit,Department of Medicine, Faculty of Medicine, Ramathibodi Hospital,
  - Bangkok, Thailand, 10400
    - Division Of cardiology,Department of Medicine,Faculty Of Medicine,Chulalongkorn University
- Bangkok
  - Bangkoknoi, Bangkok, Thailand, 10700
    - Division of Cardiology, Department of Medicine, Faculty of Medicine, Siriraj Hospital,
- Khon Kaen
  - Muang, Khon Kaen, Thailand, 40002
    - Faculty of Medicine, Srinagarind Hospital, Khon Kaen University
- Songkla
  - Hat Yai, Songkla, Thailand, 90110
    - Heart Center, Songklanagarind Prince of Songkla University
Turkey
- - Adana, Turkey, 01250
    - Baskent University, Adana Yuregir Training & Research Hospital
  - Afyonkarahisar, Turkey, 03200
    - A.karahisar Kocatepe Universitesi Hastanesi Ahmet Needet Sezer Uygulama ve
  - Ankara, Turkey, 06110
    - Diskapi Yildirim Beyazit Egitim ve Arastirma Hastanesi
  - Ankara, Turkey, 06520
    - Ufuk University School of Medicine, Dr. Ridvan Ege Training & Research Hospital
  - Antalya, Turkey, 07059
    - Akdeniz Universitesi Tip Fakultesi
  - Antalya, Turkey, 07100
    - Antalya Training & Research Hospital
  - Aydin, Turkey, 09100
    - Adnan Menderes Universitesi Uygulama ve Arastirma Hastanesi
  - Bursa, Turkey, 16320
    - Bursa Yuksek Ihtisas Egitim ve Arastirma Hastanesi
  - Elazig, Turkey, 23119
    - Firat Universitesi
  - Gaziantep, Turkey, 27310
    - Gaziantep Universitesi Tip Fakultesi Sahinbey Egitim ve Arastirma Hastanesi
  - Istanbul, Turkey, 34093
    - Istanbul Universitesi Istanbul Tip Fakultesi
  - Istanbul, Turkey, 34096
    - Istanbul Universitesi Kardiyoloji Enstitusu
  - Istanbul, Turkey, 34093
    - Bezmialem Vakif Universitesi Tip Fakultesi Kardiyoloji Bolurnu
  - Izmir, Turkey, 35340
    - Dokuz Eylul Universitesi Tip Fakultesi
  - Izmir, Turkey, 35100
    - Ege University, School of Medicine
  - Izmir, Turkey, 35170
    - Izmir Tepecik Egitim ve Arastirma Hastanesi
  - Izmir, Turkey, 35340
    - Dokuz Eylul Universitesi Tip Fakultesi Hastanesi
  - Kocaeli, Turkey, 41380
    - Kocaeli University School Of Medicine-Kocaeli Universitesi Tip Fakultesi
  - Mersin, Turkey, 33343
    - Mersin University, School of Medicine
  - Rize, Turkey, 53020
    - Recep Tayyip Erdogan University School of Medicine, Training & Research Hospital
United Kingdom
- - Barnet, United Kingdom, EN5 3DJ
    - Royal Free London NHS Foundation Trust
  - Birmingham, United Kingdom, B6 6BB
    - Laurie Pike Health Centre
  - Birmingham, United Kingdom, B9 5SS
    - Heart of England NHS Foundation Trust, Dept. of Clinical Biochemistry & Immunology
  - Cardiff, United Kingdom, CF14 5GJ
    - Synexus Wales Clinical Research Centre
  - Chesterfield, United Kingdom, S404AA
    - Ashgate Medical Practice
  - East Sussex, United Kingdom, TN39 4SP
    - Little Common Surgery
  - East Sussex, United Kingdom, TN40 1JJ
    - Sea Road Surgery
  - Ely, United Kingdom, CB7 5JD
    - Staploe Medical Centre
  - Glasgow, United Kingdom, G69 7AD
    - McGlone Practice - Ballieston Health Centre
  - Glosgow, United Kingdom, G51 4TF
    - The Queen Elizabeth University Hospital- NHS Greater Glasgow and Clyde
  - Hinckley, United Kingdom, LE10 2SE
    - Burbage Surgery
  - Liverpool, United Kingdom, L7 8XP
    - The Royal Liverpool and Broadgreen -University Hospitals NHS
  - London, United Kingdom, NW3 2QG
    - Royal Free Hospital
  - London, United Kingdom, EC1M 6BQ
    - Barts Health Nhs Trust
  - London, United Kingdom, W12 OHS
    - Peart-Rose Research Unit, Hammersmith Hospital, Imperial College NHS Trust
  - Middlesbrough, United Kingdom, TS4 3BW
    - The Red Porto cabin, The James Cook University Hospital
  - Newport, United Kingdom, PO30 5TG
    - St Mary's Hospital
  - Peterborough, United Kingdom, PE8 6PL
    - Wansford and Kings Cliffe Practice
  - Rothwell, Northants, United Kingdom, NN14 6JQ
    - Rothwell and Desborough Healthcare Group
  - Swansea, United Kingdom, SA2 8PP
    - Abertawe Bro Morgannwg University Local Health Board Joint
  - Worthing, United Kingdom, BN11 2DH
    - Western Sussex Hosptials NHS Trust
  - York, United Kingdom, YO30 6AE
    - York Medical Group
  - York, United Kingdom, YO32 5UA
    - Strensall Healthcare Centre
- Berkshire
  - Reading, Berkshire, United Kingdom, RG2 0TG
    - Synexus Thames Valley Clinical Research Centre
- Cambridgeshire
  - Peterborough, Cambridgeshire, United Kingdom, PE3 9GZ
    - Peterborough and Stamford Hospitals NHS Foundation Trust
- Cornwall
  - St Austell, Cornwall, United Kingdom, PL26 7RL
    - Brannel Surgery
- Essex
  - Romford, Essex, United Kingdom, RM7 0AG
    - Queens Hospital
- Greater Manchester
  - Manchester, Greater Manchester, United Kingdom, M15 6SX
    - Synexus Manchester Clinical Research Centre-Manchester Science Park
  - Oldham, Greater Manchester, United Kingdom, OL1 2JH
    - Royal Oldham Hospital
  - Salford, Greater Manchester, United Kingdom, M6 8HD
    - Salford Royal NHS Foundation Trust
- Hertfordshire
  - Stevenage, Hertfordshire, United Kingdom, SG1 4AB
    - Lister Hospital
  - Welwyn Garden City, Hertfordshire, United Kingdom, AL7 4HQ
    - Queen Elizabeth II Hospital, East and North Hertfordshire NHS Trust
- Kent
  - Gillingham, Kent, United Kingdom, ME7 5NY
    - Medway Maritime Hospital
- Lanarkshire
  - Glasgow, Lanarkshire, United Kingdom, G20 0SP
    - Synexus Scotland Clinical Research Centre
- Lancashire
  - Bolton, Lancashire, United Kingdom, BL4 0JR
    - Bolton NHS Foundation Trust
  - Chorley, Lancashire, United Kingdom, PR7 7NA
    - Synexus Lancashire Clinical Research Centre
  - Layton, Blackpool, Lancashire, United Kingdom, FY3 7EN
    - Layton Medical Centre
- Merseyside
  - Liverpool, Merseyside, United Kingdom, L22 0LG
    - Synexus Merseyside Clinical Research Centre
- North Yorkshire
  - Whitby, North Yorkshire, United Kingdom, YO21 1SD
    - Whitby Group Practice
- Northants
  - Wellingborough, Northants, United Kingdom, NN84RW
    - Albany House Medical Centre
- Northern Ireland
  - Portadown, Northern Ireland, United Kingdom, BT63 5QQ
    - Southern Health & Social Care Trust, Craigavon Area Hospital
- Northumberland
  - Hexham, Northumberland, United Kingdom, NE46 1QJ
    - Synexus North East Clinical Research Centre - Hexham General Hospital
- South Yorkshire
  - Doncaster, South Yorkshire, United Kingdom, DN9 2HY
    - South Axholme Practice
  - Manchester, South Yorkshire, United Kingdom, M13 9WL
    - Central Manchester University Hospitals NHS Foundation Trust
- Surrey
  - Addlestone, Surrey, United Kingdom, KT15 2BH
    - The Crouch Oak Family Practice
- WEST Midlands
  - Birmingham, WEST Midlands, United Kingdom, B15 2SQ
    - Synexus Midlands Clinical Research Centre
  - Birmingham, WEST Midlands, United Kingdom, B18 7QH
    - City Hospital
- WEST Wales
  - Llanelli, WEST Wales, United Kingdom, SF14 8QF
    - Prince Philip Hospital
- Wales
  - Cardiff, Wales, United Kingdom, CF5 4AD
    - Ely Bridge Surgery
United States
- Alabama
  - Athens, Alabama, United States, 35611
    - North Alabama Research Center, LLC
  - Athens, Alabama, United States, 35611
    - Ernest Hendrix, MD, PC
  - Birmingham, Alabama, United States, 35211
    - Clinical Research Advantage, Inc./Simon Williamson Clinic
  - Birmingham, Alabama, United States, 35209
    - Central Alabama Research
  - Birmingham, Alabama, United States, 35233
    - The Kirklin Clinic
  - Birmingham, Alabama, United States, 35235
    - Birmingham Heart Clinic, P.C.
  - Birmingham, Alabama, United States, 35294
    - University of Alabama at Birmingham (Drug Shipment)
  - Fort Payne, Alabama, United States, 35967
    - Appalachian Cardiovascular Associates
  - Gulf Shores, Alabama, United States, 36542
    - Fundamental Research, LLC
  - Guntersville, Alabama, United States, 35976
    - Avant Research Associates, LLC
  - Hamilton, Alabama, United States, 35570
    - Boyett Health Services
  - Huntsville, Alabama, United States, 35801
    - The Office of Saadat Ansari MD LLC
  - Mobile, Alabama, United States, 36608
    - CB Flock Research Corporation
- Alaska
  - Anchorage, Alaska, United States, 99508
    - Alaska Heart Institute
- Arizona
  - Glendale, Arizona, United States, 85306
    - Phoenix Heart, PLLC
  - Glendale, Arizona, United States, 85308
    - Arrowhead Internal Medicine
  - Phoenix, Arizona, United States, 85018
    - Clinical Research Advantage, Inc./Family Practice Specialists, Ltd.
  - Sierra Vista, Arizona, United States, 85635
    - Cochise Clinical Research
  - Tempe, Arizona, United States, 85282
    - Clinical Research Advantage, Inc. (Administrative Mailing Only)
  - Tucson, Arizona, United States, 85710
    - Southwest Heart Group
  - Tucson, Arizona, United States, 85715
    - Arizona Endocrine and Rheumatology Associates
- Arkansas
  - Little Rock, Arkansas, United States, 72211
    - Arkansas Heart Hospital Clinic
  - Little Rock, Arkansas, United States, 72211
    - Arkansas Site Management Services, LLC
- California
  - Anaheim, California, United States, 92801
    - Cardiology Consultants of Orange County Medical Group, Inc.
  - Bakersfield, California, United States, 93309
    - Premier Valley Medical Group
  - Beverly Hills, California, United States, 90211
    - Westside Medical Associates of Los Angeles
  - Beverly Hills, California, United States, 90210
    - Cardiovascular Research Foundation of Southern California
  - Buena Park, California, United States, 90620
    - Southbay Pharma Research
  - Cerritos, California, United States, 90703
    - Pioneer Medical Group
  - Concord, California, United States, 94520
    - John Muir Physician Network Clinical Research Center
  - Cudahy, California, United States, 90201
    - Atlantic Ave Medical Clinic Inc.
  - Downey, California, United States, 90241
    - Multani Medical Group
  - El Cajon, California, United States, 92020
    - TriWest Research Associates, LLC
  - Encinitas, California, United States, 92024
    - Diagnamics Inc.
  - Encino, California, United States, 91436
    - T. Joseph Raoof, Md, Inc/Encino Research Center
  - Escondido, California, United States, 92025
    - AVIVA Research
  - Fresno, California, United States, 93720
    - Valley Research
  - Fullerton, California, United States, 92835
    - St. Jude Hospital Yorba Linda dba St. Joseph Heritage Healthcare
  - La Palma, California, United States, 90623
    - Omnibus Clinical Research
  - Laguna Hills, California, United States, 92653
    - Alliance Research Centers
  - Laguna Hills, California, United States, 92653
    - Prime Care Clinical Research Center
  - Lincoln, California, United States, 95648
    - Clinical Trials Research
  - Long Beach, California, United States, 90806
    - Long Beach Memorial Medical Center
  - Los Angeles, California, United States, 90022
    - Academic Medical Research Institute
  - Los Angeles, California, United States, 90017
    - American Institute of Research
  - Los Angeles, California, United States, 90017
    - Intermed Group
  - Los Angeles, California, United States, 90022
    - Eastside Clinical Research Associates
  - Los Gatos, California, United States, 95032
    - Richard S. Cherlin, MD
  - Mission Hills, California, United States, 91345
    - Facey Medical Foundation
  - Northridge, California, United States, 91325
    - Valley Clinical Trials, Inc.
  - Northridge, California, United States, 91324
    - California Medical Research Associates Inc.
  - Orange, California, United States, 92868
    - Diabetes Associates Medical Group
  - Port Hueneme, California, United States, 93041
    - Saviers Medical Group
  - San Diego, California, United States, 92103-6204
    - California Research Foundation
  - San Diego, California, United States, 92111
    - San Diego Family Care dba Linda Vista Health Center
  - San Diego, California, United States, 92111
    - San Diego Family Care
  - San Diego, California, United States, 92117
    - Ritchken & First Md's
  - San Diego, California, United States, 92120
    - Wetlin Research Associates, Inc.
  - San Ramon, California, United States, 94582
    - West Coast Research LLC
  - Santa Ana, California, United States, 92705
    - Syrentis Clinical Research
  - Santa Monica, California, United States, 90404
    - Coastal Biomedical Research, Inc.
  - Spring Valley, California, United States, 91978
    - Encompass Clinical Research
  - Stockton, California, United States, 95204
    - St. Joseph's Medical Associates
  - Thousand Oaks, California, United States, 91360
    - Westlake Medical Research
  - Torrance, California, United States, 90502
    - Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
  - Torrance, California, United States, 90502-2004
    - Harbor-UCLA Medical Center - Torrance
  - Valley Village, California, United States, 91607
    - Bayview Research Group
  - Ventura, California, United States, 93003
    - Ventura Clinical Trials
  - Ventura, California, United States, 93003
    - Coastal Metabolic Research Centre
  - Vista, California, United States, 92083
    - Clinical Research Advantage, Inc. / Cassidy Medical Group - Vista
  - Westminster, California, United States, 92683
    - Allianz Research Institute
  - Whittier, California, United States, 90603
    - American Institute of Research
  - Whittier, California, United States, 90603
    - American Institute of Research Studies
  - Wildomar, California, United States, 92595
    - Elite Clinical Trials, Inc.
  - Wildomar, California, United States, 92595
    - Elite Clinical Trials, Incorporated
- Colorado
  - Colorado Springs, Colorado, United States, 80909
    - Lynn Institute Of The Rockies
  - Colorado Springs, Colorado, United States, 80906
    - Colorado Springs Health Partners
  - Colorado Springs, Colorado, United States, 80909
    - Memorial Hospital: University of Colorado Health
  - Denver, Colorado, United States, 80246
    - Lynn Institute of Denver
  - Glenwood Springs, Colorado, United States, 81601
    - Western Colorado Research, LLC
  - Littleton, Colorado, United States, 80120
    - South Denver Cardiology Associates, PC
- Connecticut
  - Bridgeport, Connecticut, United States, 06610
    - Bridgeport Hospital
  - Bridgeport, Connecticut, United States, 06606
    - Connecticut Clinical Research, Llc
  - Stamford, Connecticut, United States, 06905
    - Stamford Therapeutics Consortium
  - Stamford, Connecticut, United States, 06905
    - Cardiology Associates of Fairfield County, PC
- Delaware
  - Newark, Delaware, United States, 19713
    - Christiana Care Health Services, Inc.
  - Wilmington, Delaware, United States, 19803
    - Alfieri Cardiology
- Florida
  - Atlantis, Florida, United States, 33462
    - ACRC - Cardiology
  - Clearwater, Florida, United States, 33756
    - Gulfcoast Endocrine and Diabetes Center
  - Clearwater, Florida, United States, 33756
    - Morton Plant Mease Health Care, Inc. Cardiovascular Research
  - Coral Gables, Florida, United States, 33134
    - Team Medical Research
  - Daytona Beach, Florida, United States, 32117
    - Cardiology Associates Research Company
  - Daytona Beach, Florida, United States, 32114
    - The Heart Group, PA
  - Delray Beach, Florida, United States, 33484
    - The Cardiology Center
  - Doral, Florida, United States, 33166
    - Integrity Clinical Research, LLC
  - Doral, Florida, United States, 33166
    - Moonshine Research Center, Inc.
  - Doral, Florida, United States, 33166
    - Care Research Center Inc
  - Doral, Florida, United States, 33126
    - Continental Research Corp
  - Fort Lauderdale, Florida, United States, 33316
    - Broward Health Medical Center
  - Fort Lauderdale, Florida, United States, 33308
    - InvesClinic, LLC
  - Fort Lauderdale, Florida, United States, 33316
    - The Office of Maxine E. Hamilton, MD, PA
  - Fort Lauderdale, Florida, United States, 33308
    - The Office of Dr. Alan Graff, MD, PA
  - Hialeah, Florida, United States, 33010
    - State Of The Art Research, LLC
  - Hialeah, Florida, United States, 33012
    - Direct Helpers Medical Center Inc
  - Hollywood, Florida, United States, 33021
    - Research Physicians Network Alliance
  - Hollywood, Florida, United States, 33024
    - Pines Clinical Research, Inc.
  - Jacksonville, Florida, United States, 32205
    - Westside Center for Clinical Research
  - Jacksonville, Florida, United States, 32216
    - Jacksonville Center for Clinical Research
  - Jacksonville, Florida, United States, 32216
    - East Coast Institute for Research, LLC
  - Jacksonville, Florida, United States, 32256
    - Solutions Through Advanced Research, Inc.
  - Jacksonville, Florida, United States, 32204
    - East Coast Institute for Research, LLC
  - Jacksonville, Florida, United States, 32207
    - River City Clinical Research
  - Jacksonville, Florida, United States, 32223
    - Baker-Gilmore Cardiovascular Institute
  - Jacksonville, Florida, United States, 32216
    - East Coast Institute for Reserach, LLC
  - Jacksonville, Florida, United States, 32216
    - The Office of Rachel Day
  - Lakeland, Florida, United States, 33805
    - Meridien Research
  - Largo, Florida, United States, 33770
    - The Heart Institute at Largo
  - Margate, Florida, United States, 33063
    - South Florida Clinical Research Institute
  - Miami, Florida, United States, 33144
    - Medical Research Center
  - Miami, Florida, United States, 33183
    - International Research Associates, LLC
  - Miami, Florida, United States, 33147
    - Advanced Pharma CR, LLC
  - Miami, Florida, United States, 33126
    - Finlay Medical Research
  - Miami, Florida, United States, 33126
    - Pharmax Research Clinic, Inc.
  - Miami, Florida, United States, 33135
    - South Florida Research Center, Inc.
  - Miami, Florida, United States, 33185
    - Kendall South Medical Center, Inc.
  - Miami, Florida, United States, 33144
    - Nuren Medical & Research Center
  - Miami, Florida, United States, 33186
    - Med Research Of Florida, LLC
  - Miami, Florida, United States, 33173
    - Research Institute of South Florida, Inc.
  - Miami, Florida, United States, 33122
    - Future Clinical Research, Inc.
  - Miami, Florida, United States, 33125
    - Advanced Clinical Research of Miami (ACROM) International
  - Miami, Florida, United States, 33125
    - Project4Research, Inc
  - Miami, Florida, United States, 33126
    - A & L Clinical research
  - Miami, Florida, United States, 33142
    - Florida Medical Center & Research, Inc.
  - Miami, Florida, United States, 33145
    - Doctors Research Institute
  - Miami, Florida, United States, 33155
    - Coast Research Institute
  - Miami, Florida, United States, 33155
    - My Community Research Center, Inc.
  - Miami, Florida, United States, 33165
    - Columbus Clinical Services LLC
  - Miami, Florida, United States, 33173
    - Cardiovascular Research Center of South Florida
  - Miami, Florida, United States, 33174
    - A & O Research Center, Inc.
  - Miami, Florida, United States, 33175
    - BWell Research Center
  - Miami, Florida, United States, 33175
    - Pharmacology International Research, Inc.
  - Miami, Florida, United States, 33176
    - Advanced Clinical Research
  - Miami, Florida, United States, 33176
    - South Florida Research Group, LLC
  - Miami, Florida, United States, 33185
    - M & M Medical Center, Inc
  - Miami, Florida, United States, 33134
    - Team Medical Research, Inc.
  - Miami, Florida, United States, 33134
    - Team Medical Research
  - Miami, Florida, United States, 33185
    - Kendall South Medical Center, Inc
  - Miami Beach, Florida, United States, 33140
    - Research Physicians Network Alliance
  - Miami Lakes, Florida, United States, 33014
    - G & I Medical Research LLC
  - Miami Springs, Florida, United States, 33166
    - Ocean Blue Medical Research Center, Inc.
  - Naples, Florida, United States, 34102
    - Southwest Florida Research, LLC
  - New Port Richey, Florida, United States, 34653
    - BayCare Medical Group
  - New Port Richey, Florida, United States, 34653
    - The Heart & Vascular Institute Of Florida
  - North Bay Village, Florida, United States, 33141
    - Bravo Health Care Center
  - North Miami Beach, Florida, United States, 33162
    - Harmony Clinical Research, Inc.
  - Orlando, Florida, United States, 32803
    - Florida Hospital
  - Orlando, Florida, United States, 32806
    - Omega Research Consultants, LLC
  - Ormond Beach, Florida, United States, 32174
    - Millennium Research
  - Ormond Beach, Florida, United States, 32174
    - Aba Family Medicine, LLC
  - Ormond Beach, Florida, United States, 32174
    - Ribo Research, LLC dba Peninsula Research
  - Pembroke Pines, Florida, United States, 33029
    - DBC Research USA
  - Pembroke Pines, Florida, United States, 33027
    - South Broward Research
  - Pembroke Pines, Florida, United States, 33025
    - Research Physicians Network Alliance
  - Pembroke Pines, Florida, United States, 33029
    - DBC Research
  - Pembroke Pines, Florida, United States, 33024
    - A and R Research Group LLC
  - Pensacola, Florida, United States, 32501
    - Cardiology Consultants
  - Pinellas Park, Florida, United States, 33782
    - DMI Research, Inc.
  - Plant City, Florida, United States, 33563
    - Clinical Research of Central Florida
  - Plant City, Florida, United States, 33563
    - Clinical Research of Florida
  - Plantation, Florida, United States, 33313-6066
    - Jeffrey D Greff,MD
  - Ponte Vedra, Florida, United States, 32081
    - St. Johns Center for Clinical Research
  - Port Charlotte, Florida, United States, 33952
    - Charlotte Heart Group Research Center
  - Saint Petersburg, Florida, United States, 33709
    - Meridien Research
  - Saint Petersburg, Florida, United States, 33713
    - Advance Medical Research
  - Sarasota, Florida, United States, 34239
    - Cardiovascular Center of Sarasota
  - Sarasota, Florida, United States, 34232
    - Intercoastal Medical Group
  - Sarasota, Florida, United States, 34239
    - Heart & Vascular Center Research
  - Sarasota, Florida, United States, 34239
    - Intercoastal Medical Group (Drug Shipment Address and Administrative)
  - Sarasota, Florida, United States, 34233
    - Intercoastal Medical Group
  - Seminole, Florida, United States, 33777
    - The Office of Bridget Bellingar, DO
  - Tamarac, Florida, United States, 33319
    - Vita Health & Medical Center, Inc./Concept Clinical Trials, LLC
  - Trinity, Florida, United States, 34655
    - Interventional Cardiac Consultants
  - Wellington, Florida, United States, 33449
    - Cardiology Partners Clinical Research Institute
  - West Palm Beach, Florida, United States, 33401
    - Metabolic Research Institute, Inc.
  - West Palm Beach, Florida, United States, 33401
    - Cleveland Clinic Cardiology Associates
  - Winter Haven, Florida, United States, 33880
    - Clinical Research of Central Florida
- Georgia
  - Atlanta, Georgia, United States, 30322
    - Emory University Hospital
  - Atlanta, Georgia, United States, 30318
    - Atlanta Diabetes Associates
  - Atlanta, Georgia, United States, 30331
    - Atlanta Center for Medical Research
  - Columbus, Georgia, United States, 31904
    - Columbus Regional Research Institute
  - Conyers, Georgia, United States, 30094
    - Rockdale Medical Research Associates
  - Covington, Georgia, United States, 30014
    - Georgia Heart Specialists, LLC
  - Decatur, Georgia, United States, 30033
    - NeuroStudies.net, LLC
  - Dunwoody, Georgia, United States, 30338
    - Alta Pharmaceutical Research Center
  - Norcross, Georgia, United States, 30071
    - In-Quest Medical Research, LLC
  - Roswell, Georgia, United States, 30075
    - Atlanta Center for Clinical Research / Internal Medicine
  - Snellville, Georgia, United States, 30078
    - Georgia Clinical Research, LLC
  - Snellville, Georgia, United States, 30039
    - Dr. B. Abraham, P.C.
  - Stockbridge, Georgia, United States, 30281
    - Clinical Research Atlanta
- Hawaii
  - Honolulu, Hawaii, United States, 96814
    - East-West Medical Research Institute
- Idaho
  - Blackfoot, Idaho, United States, 83221
    - Elite Clinial Trials, LLLP
  - Blackfoot, Idaho, United States, 83221
    - Elite Clinical Trials (Additional Administrative Room / Exam Rooms)
  - Caldwell, Idaho, United States, 83605
    - St. Luke's Idaho Cardiology Associates
  - Meridian, Idaho, United States, 83646
    - Solaris Clinical Research
  - Nampa, Idaho, United States, 83686-6011
    - Saltzer Medical Group, PA
- Illinois
  - Arlington Heights, Illinois, United States, 60005
    - Northwest Heart Clinical Research, LLC
  - Chicago, Illinois, United States, 60604
    - Clinical Research Advantage, Inc./Michigan Avenue Internists
  - Chicago, Illinois, United States, 60616
    - Apex Medical Research, AMR, Inc.
  - Chicago, Illinois, United States, 60631
    - Clinical Research Advantage,Inc./Medical and Procedural Specilaists of Illinois
  - Evanston, Illinois, United States, 60201
    - Evanston Premier Healthcare Research, LLC
  - Gurnee, Illinois, United States, 60031
    - Clinical Investigation Specialists, Inc
  - Mokena, Illinois, United States, 60448
    - Heart Care Centers of Illinois
  - Rock Island, Illinois, United States, 61201
    - Advanced Cardiovascular Consultants
- Indiana
  - Brownsburg, Indiana, United States, 46112
    - Investigators Research Group, LLC
  - Elwood, Indiana, United States, 46036
    - Investigative Clinical Research of Indiana, LLC
  - Evansville, Indiana, United States, 47714
    - Medisphere Medical Research Center, Llc
  - Evansville, Indiana, United States, 47714
    - Clinical Research Advantage, Inc.
  - Evansville, Indiana, United States, 47725
    - Deaconess Clinic Mt. Pleasant
  - Evansville, Indiana, United States, 47713
    - Deaconess Clinic Downtown
  - Evansville, Indiana, United States, 47725
    - Clinical Research Advantage, Inc. / Family Medicine Associates
  - Franklin, Indiana, United States, 46131
    - American Health Network of Indiana LLC
  - Greenfield, Indiana, United States, 46140
    - American Health Network of Indiana LLC
  - Muncie, Indiana, United States, 47304
    - American Health Network of Indiana, LLC
  - Munster, Indiana, United States, 46321
    - Cardiovascular Research of Northwest Indiana, LLC
  - Valparaiso, Indiana, United States, 46383
    - Buynak Clinical Research, P.C.
- Iowa
  - Council Bluffs, Iowa, United States, 51501
    - West Broadway Clinic
  - Council Bluffs, Iowa, United States, 51503
    - Clinical Research Advantage, Inc.
  - Davenport, Iowa, United States, 52803
    - Midwest Cardiovascular Research Foundation
  - Iowa City, Iowa, United States, 52242
    - University of Iowa-College of Public Health-Preventive Intervention Center
  - Waterloo, Iowa, United States, 50702
    - Northeast Iowa Medical Education Foundation
  - West Des Moines, Iowa, United States, 50266
    - The Iowa Clinic, PC
- Kansas
  - Hutchinson, Kansas, United States, 67502
    - Hutchinson Clinic, P.A
  - Kansas City, Kansas, United States, 66160
    - University of Kansas Medical Center
  - Overland Park, Kansas, United States, 66209
    - Midwest Heart & Vascular Specialists, LLC
  - Shawnee Mission, Kansas, United States, 66218
    - Women's & Family Care, LLC D.B.A GTC Research
  - Shawnee Mission, Kansas, United States, 66218
    - Women's & Family Care D.B.A. GTC Research
  - Shawnee Mission, Kansas, United States, 66218
    - Women's & Family Care, LLC D.B.A. GTC Research
- Kentucky
  - Elizabethtown, Kentucky, United States, 42701
    - Central Cardiology Associates Research
  - Lexington, Kentucky, United States, 40503
    - The Research Group of Lexington, LLC
  - Louisville, Kentucky, United States, 40213
    - L-MARC
  - Owensboro, Kentucky, United States, 42303
    - Research Integrity, LLC.
- Louisiana
  - Bossier City, Louisiana, United States, 71111
    - Grace Research, LLC
  - Crowley, Louisiana, United States, 70526
    - Avant Research Associates, LLC
  - Lake Charles, Louisiana, United States, 70601
    - Centex Studies
  - Lake Charles, Louisiana, United States, 70601
    - Imperial Health, LLP
  - Marrero, Louisiana, United States, 70072
    - American Clinical Research, LLC
  - Marrero, Louisiana, United States, 70072
    - West Jefferson Heart Clinic of Louisiana New Orleans Physician Services, Inc.
  - Monroe, Louisiana, United States, 71201
    - Clinical Trials of America LA
  - Natchitoches, Louisiana, United States, 71457
    - KAMP Medical Research Inc.
  - New Orleans, Louisiana, United States, 70112
    - Clinical and Translation Research Center (CTRC) University Medical Center of New Orleans, Diagnostic
  - New Orleans, Louisiana, United States, 70112
    - Section of Nephrology and Hypertension, LSU Health Sciences Center-New Orleans
- Maine
  - Auburn, Maine, United States, 04210
    - Maine Research Associates
  - Bangor, Maine, United States, 04401
    - Acadia Clinical Research, LLC
  - Bangor, Maine, United States, 04401
    - Acadia Clinical Research
  - Cape Elizabeth, Maine, United States, 04107
    - Cranbrook Cardiology Research Associates
- Maryland
  - Annapolis, Maryland, United States, 21401
    - Anne Arundel Medical Center
  - Annapolis, Maryland, United States, 21401
    - Medstar Cardiology Associates
  - Baltimore, Maryland, United States, 21229
    - Maryland Cardiovascular Specialists
  - Baltimore, Maryland, United States, 21236
    - Overlea Personal Physicians
  - Baltimore, Maryland, United States, 21204
    - MedStar Chesapeake CardioVascular Associates
  - Baltimore, Maryland, United States, 21218
    - Medstar Union Memorial Heart Specialists
  - Baltimore, Maryland, United States, 21237
    - Shahid Saeed, MD, PC
  - Glen Burnie, Maryland, United States, 21061
    - Maryland Heart Associates, LLC
  - Lutherville, Maryland, United States, 21093
    - Lutherville Personal Physicians
  - Oxon Hill, Maryland, United States, 20745
    - MD Medical Research
- Massachusetts
  - Framingham, Massachusetts, United States, 01702
    - MetroWest Medical Center
  - Framingham, Massachusetts, United States, 01702
    - MetroWest Medical Center - Pharmacy Department
  - Framingham, Massachusetts, United States, 01702
    - MetroWest Medical Center Research Clinic
  - Methuen, Massachusetts, United States, 01844
    - ActivMed Practices and Research, Inc.
  - Natick, Massachusetts, United States, 01760
    - Charles River Medical Associates
- Michigan
  - Alpena, Michigan, United States, 49707
    - Endeavor Medical Research
  - Ann Arbor, Michigan, United States, 48106
    - University of Michigan - Domino Farms
  - Ann Arbor, Michigan, United States, 48106
    - St. Joseph Mercy Health System (Drug shipment Only)
  - Bingham Farms, Michigan, United States, 48025
    - QUEST Research Institute
  - Chelsea, Michigan, United States, 48118
    - IHA Chelsea Family & Internal Medicine
  - Grandville, Michigan, United States, 49418
    - Healthy Heart Cardiology
  - Kalamazoo, Michigan, United States, 49009
    - Westside Family Medical Center, Pc
  - Lansing, Michigan, United States, 48912
    - Sparrow Clinical Research Institute
  - Lansing, Michigan, United States, 48912
    - Sparrow Thoracic & Cardiovascular Institute
  - Livonia, Michigan, United States, 48154
    - Detroit Clinical Research Center, PC
  - Midland, Michigan, United States, 48670
    - MidMichigan Medical Center Midland
  - Saginaw, Michigan, United States, 48601
    - Michigan Cardio Vascular Institute
  - Sterling Heights, Michigan, United States, 48310
    - Tri-County Research, Inc.
  - Traverse City, Michigan, United States, 49684
    - Medical Research Associates, Inc.
  - Troy, Michigan, United States, 48085
    - Oakland Medical Research Center
  - Troy, Michigan, United States, 48098
    - Arcturus Healthcare, plc, Troy Internal Medicine Research Division
  - Ypsilanti, Michigan, United States, 48197
    - Michigan Heart & Vascular Institute
- Minnesota
  - Duluth, Minnesota, United States, 55805
    - St. Mary's Medical Center
  - Duluth, Minnesota, United States, 55805
    - Duluth Clinic, dba Essentia Health Duluth Clinic Investigational Drug Room
  - Duluth, Minnesota, United States, 55805
    - The Duluth Clinic, Ltd.
  - Duluth, Minnesota, United States, 55805
    - St. Mary's Medical Center dba Essentia Health St. Mary's Medical Center
  - Edina, Minnesota, United States, 55435
    - Radiant Research, Inc.
  - Golden Valley, Minnesota, United States, 55422
    - Minneapolis Clinic of Neurology
  - Minneapolis, Minnesota, United States, 55407
    - Allina Health System, dba Abbott Northwestern Hospital
  - Minneapolis, Minnesota, United States, 55455
    - Lillehei Clinical Research Unit, University of Minnesota
  - Saint Cloud, Minnesota, United States, 56303
    - CentraCare Heart and Vascular Center
  - Saint Paul, Minnesota, United States, 55102
    - HealthEast St. Joseph's Hospital inpatient Pharmacy
- Mississippi
  - Olive Branch, Mississippi, United States, 38654
    - Olive Branch Family Medical Center
  - Tupelo, Mississippi, United States, 38801
    - Cardiology Associates Research, LLC
- Missouri
  - Columbia, Missouri, United States, 65201
    - Missouri Cardiovascular Specialists, LLP
  - Kansas City, Missouri, United States, 64111
    - Saint Luke's Lipid and Diabetes Research Center
  - Kansas City, Missouri, United States, 64128-2226
    - Kansas City VA Medical Center
  - Saint Louis, Missouri, United States, 63141
    - Mercy Research
- Montana
  - Kalispell, Montana, United States, 59901
    - Glacier View Research Institute, Cardiology
  - Missoula, Montana, United States, 59808
    - Montana Medical Research Inc.
- Nebraska
  - Lincoln, Nebraska, United States, 68506
    - Bryan Heart
  - Omaha, Nebraska, United States, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, United States, 68131
    - Creighton Diabetes Research Center
- Nevada
  - Las Vegas, Nevada, United States, 89119
    - AB Clinical Trials
  - Las Vegas, Nevada, United States, 89121
    - Clinical Research of South Nevada
  - Las Vegas, Nevada, United States, 89128
    - Clinical Research Advantage, Inc.
- New Jersey
  - Belvidere, New Jersey, United States, 07823
    - John V. Bernard, MD dba Wellness and Research Center
  - Bridgewater, New Jersey, United States, 08807
    - Advanced Heart Care LLC
  - Cherry Hill, New Jersey, United States, 08034
    - Lourdes Cardiology Services
  - Elizabeth, New Jersey, United States, 07201
    - USMA Clinical Research
  - Hammonton, New Jersey, United States, 08037
    - Lourdes Cardiology Services
  - Linden, New Jersey, United States, 07036
    - NJ Heart
  - Lodi, New Jersey, United States, 07644
    - Arysmed LLC
  - Martinsville, New Jersey, United States, 08836
    - Amici Clinical Research, LLC
  - New Brunswick, New Jersey, United States, 08901
    - Rutgers Biomedical and Health Sciences-Robert Wood Johnson Medical School
  - Ridgewood, New Jersey, United States, 07450
    - The Valley Hospital
  - Ridgewood, New Jersey, United States, 07450
    - Cardiac & Endovascular Associates
  - Somerset, New Jersey, United States, 08873
    - Cardio Metabolic Institute
  - Trenton, New Jersey, United States, 08611
    - TLB Research LLC
  - Voorhees, New Jersey, United States, 08043
    - Lourdes Cardiology Services
  - Westwood, New Jersey, United States, 07675
    - Westwood Cardiology Associates, P.A.
- New Mexico
  - Albuquerque, New Mexico, United States, 87102
    - Albuquerque Clinical Trials, Inc.
- New York
  - Albany, New York, United States, 12206
    - Albany Medical College, Division of Community Endocrinology
  - Brooklyn, New York, United States, 11235
    - NY Scientific
  - Brooklyn, New York, United States, 11214
    - Sorin Medical, P.C.
  - Brooklyn, New York, United States, 11215
    - NY Total Medical Care, PC
  - Buffalo, New York, United States, 14215
    - Buffalo Heart Group, LLP
  - Cortlandt Manor, New York, United States, 10567
    - NYU Hudson Valley Cardiology
  - Laurelton, New York, United States, 11413
    - Scott Research,Inc
  - Liverpool, New York, United States, 13088
    - SJH Cardiology Associates
  - Mineola, New York, United States, 11501
    - Long Island Heart Associates
  - New Windsor, New York, United States, 12553
    - Mid Hudson Medical Research, PLLC
  - New York, New York, United States, 10065
    - Weill Cornell Medical College
  - New York, New York, United States, 10016
    - Manhattan Medical Research Practice
  - New York, New York, United States, 10016
    - Peters Medical Research NY, LLC
  - North Massapequa, New York, United States, 11758-1802
    - DiGiovanna Institute for Medical Education And Research
  - Poughkeepsie, New York, United States, 12601
    - Hudson Valley Cardiovascular Practice, PC
  - Rochester, New York, United States, 14609
    - Rochester Clinical Research, Inc.
  - Rosedale, New York, United States, 11422
    - Institute for clinical studies
  - Saratoga Springs, New York, United States, 12866
    - Saratoga Clinical Research, LLC
  - Utica, New York, United States, 13501
    - Central New York Cardiology
  - Westfield, New York, United States, 14787
    - Great Lakes Medical Research
  - Williamsville, New York, United States, 14221
    - Buffalo Medical Group
- North Carolina
  - Charlotte, North Carolina, United States, 28204
    - Novant Health Heart and Vascular Institute
  - Charlotte, North Carolina, United States, 28204
    - Novant Health Clinical Research
  - Charlotte, North Carolina, United States, 28277
    - Sensenbrenner Primary Care
  - Clayton, North Carolina, United States, 27520
    - NC Heart and Vascular
  - Greensboro, North Carolina, United States, 27401
    - LeBauer Cardiovascular Research Foundation
  - Hickory, North Carolina, United States, 28601
    - Clinical Trials of America, Inc.
  - High Point, North Carolina, United States, 27262
    - Carolina Cardiology Cornerstone
  - Lenoir, North Carolina, United States, 28645
    - Clinical Trials of America- NC, LLC
  - Mooresville, North Carolina, United States, 28117
    - Research Institute of the Carolinas of Piedmont Healthcare, PA
  - Morganton, North Carolina, United States, 28655
    - Burke Primary Care
  - New Bern, North Carolina, United States, 28562
    - Eastern Nephrology Associates
  - Rocky Mount, North Carolina, United States, 27804
    - PMG Research of Rocky Mount, LLC
  - Rocky Mount, North Carolina, United States, 27804
    - Boice Willis Clinic
  - Smithfield, North Carolina, United States, 27577
    - NC Heart and Vascular Research
  - Statesville, North Carolina, United States, 28625
    - Piedmont Healthcare/Research
  - Winston-Salem, North Carolina, United States, 27157
    - Wake Forest University Health Sciences Institutional Review Board
- North Dakota
  - Fargo, North Dakota, United States, 58103
    - Lillestol Research LLC
- Ohio
  - Akron, Ohio, United States, 44311
    - Radiant Research, Inc
  - Cincinnati, Ohio, United States, 45246
    - Sterling Research Group, Ltd.
  - Cincinnati, Ohio, United States, 45227
    - Metabolic and Atherosclerosis Research Center
  - Cincinnati, Ohio, United States, 45219
    - The Lindner Center for Research and Education at The Christ Hospital
  - Cleveland, Ohio, United States, 44122
    - Rapid Medical Research, Inc.
  - Cleveland, Ohio, United States, 44195
    - Cleveland Clinic - Taussig Cancer Institute
  - Columbus, Ohio, United States, 43235
    - Optimed Research, LTD
  - Columbus, Ohio, United States, 43212
    - Radiant Research, Inc.
  - Dayton, Ohio, United States, 45419
    - PriMed Clinical Research
  - Dayton, Ohio, United States, 45414
    - Dayton Heart Center
  - Dayton, Ohio, United States, 45414
    - Premier Health Specialists, Inc. (dba Dayton Heart Center)
  - Delaware, Ohio, United States, 43015
    - Delaware Research Group, LLC
  - Elyria, Ohio, United States, 44035
    - North Ohio Heart Center
  - Elyria, Ohio, United States, 44035
    - North Ohio Heart Center (Administrative Only)
  - Lorain, Ohio, United States, 44053
    - North Ohio Heart Center
  - Marion, Ohio, United States, 43302
    - SV Research LLC
  - Perrysburg, Ohio, United States, 43551
    - Office of Daniel G. Williams, MD
  - Sandusky, Ohio, United States, 44870
    - North Ohio Heart Center, Inc.
  - Toledo, Ohio, United States, 43615
    - ProMedica Northwest Ohio Cardiology Consultants
  - Youngstown, Ohio, United States, 44501
    - Mercy Health Youngstown, LLC d/b/a St. Elizabeth Youngstown Hospital
- Oklahoma
  - Norman, Oklahoma, United States, 73072
    - Lion Research
  - Norman, Oklahoma, United States, 73069
    - Lion Research
  - Oklahoma City, Oklahoma, United States, 73135
    - South Oklahoma Heart Research, LLC
  - Oklahoma City, Oklahoma, United States, 73120
    - Oklahoma Heart Hospital Research Foundation
  - Oklahoma City, Oklahoma, United States, 73103
    - COR Clinical Research LLC
  - Oklahoma City, Oklahoma, United States, 73120
    - Oklahoma Heart Hospital Physicians
- Oregon
  - Ashland, Oregon, United States, 97520
    - Integrated Medical Research PC
  - Hillsboro, Oregon, United States, 97123
    - Hillsboro Cardiology, PC
  - Portland, Oregon, United States, 97225
    - Portland Preventive Cardiology LLC
- Pennsylvania
  - Abington, Pennsylvania, United States, 19001
    - Abington Hosptial
  - Altoona, Pennsylvania, United States, 16602
    - Clinical Research Associates of Central PA
  - Downingtown, Pennsylvania, United States, 19335-2620
    - Brandywine Clinical Research
  - Doylestown, Pennsylvania, United States, 18901
    - Doylestown Cardiology Associates - VIAA
  - Doylestown, Pennsylvania, United States, 18901
    - Doylestown Health Cardiology, a division of Doylestown Health Physicians
  - Feasterville-Trevose, Pennsylvania, United States, 19053
    - Amh/Feasterville Family Health Care Center
  - Jefferson Hills, Pennsylvania, United States, 15025
    - Greater Pittsburgh Vascular
  - Lansdale, Pennsylvania, United States, 19446
    - Green and Seidner Family Practice Associates
  - Lansdale, Pennsylvania, United States, 19446
    - Detweiler Family Medicine and Associates, PC
  - Levittown, Pennsylvania, United States, 19056
    - Family Medical Associates
  - Newtown, Pennsylvania, United States, 18940
    - Mercer Bucks Cardiology
  - Philadelphia, Pennsylvania, United States, 19146
    - Philadelphia Health Associates-Adult Medicine
  - Pittsburgh, Pennsylvania, United States, 15236
    - Preferred Primary Care Physicians
  - Pittsburgh, Pennsylvania, United States, 15212
    - Allegheny Endocrinology Associates
  - Sayre, Pennsylvania, United States, 18840
    - Guthrie Medical Group, PC
  - Scotland, Pennsylvania, United States, 17254
    - SFM Clinical Trials, Inc.
  - Scottdale, Pennsylvania, United States, 15683
    - Fay-West Family Practice
  - Sellersville, Pennsylvania, United States, 18960
    - Grand View - Lehigh Valley Health Services, Buxmont Cardiology Division
  - Smithfield, Pennsylvania, United States, 15478
    - Montgomery Medical, Inc.
  - Uniontown, Pennsylvania, United States, 15401
    - Preferred Primary Care Physicians
  - Wyomissing, Pennsylvania, United States, 19610
    - Berks Cardiologists, Ltd.
- South Carolina
  - Charleston, South Carolina, United States, 29407
    - Coastal Cardiology
  - Greenville, South Carolina, United States, 29615
    - Upstate Pharmaceutical Research
  - Greer, South Carolina, United States, 29651
    - Mountain View Clinical Research, Inc.
  - Murrells Inlet, South Carolina, United States, 29576
    - The Diabetes Center, LLC
- South Dakota
  - Rapid City, South Dakota, United States, 57701
    - Black Hills Cardiovascular-Regional Health Research
- Tennessee
  - Clarksville, Tennessee, United States, 37043
    - Mid-Cumberland Infectious Disease Consultants, PLC
  - Collierville, Tennessee, United States, 38017
    - Collierville Medical Specialists
  - Germantown, Tennessee, United States, 38138
    - Stern Cardiovascular Foundation, Inc.
  - Kingsport, Tennessee, United States, 37660
    - Holston Medical Group
  - Knoxville, Tennessee, United States, 37920
    - New Orleans Center for Clinical Research
  - Knoxville, Tennessee, United States, 37920
    - Volunteer Research Group
  - Knoxville, Tennessee, United States, 37909
    - New Phase Research & Development
  - Knoxville, Tennessee, United States, 37912
    - PMG Research,Inc d/b/a PMG Research of Knoxville
  - Knoxville, Tennessee, United States, 37917
    - Cardiovascular Research of Knoxville
  - Memphis, Tennessee, United States, 38119
    - Baptist Memorial Medical Group, Inc.
  - Memphis, Tennessee, United States, 38119
    - The Green Clinic, PC
  - Memphis, Tennessee, United States, 38125
    - Southwind Medical Specialists
  - Tullahoma, Tennessee, United States, 37388
    - Tennessee Center For Clinical Trials
  - Tullahoma, Tennessee, United States, 37388
    - Trinity Clinical Research, LLC
- Texas
  - Amarillo, Texas, United States, 79106
    - PharmaTex Research
  - Arlington, Texas, United States, 76012
    - Arlington Family Research Center, Inc.
  - Austin, Texas, United States, 78731
    - Texas Diabetes & Endocrinology
  - Austin, Texas, United States, 78756
    - Austin Heart, PLLC
  - Channelview, Texas, United States, 77530
    - Aztec Medical Research, LLC
  - Corsicana, Texas, United States, 75110
    - Corsicana Medical Research, PLLC
  - Dallas, Texas, United States, 75230
    - Dallas Diabetes and Endocrine Center
  - Dallas, Texas, United States, 75231
    - Research Institute of Dallas
  - Dallas, Texas, United States, 75231
    - Cardiovascular Research Institute of Dallas
  - Dallas, Texas, United States, 75231
    - Radiant Research, Inc.
  - Dallas, Texas, United States, 75208
    - Protenium Clinical Research, LLC
  - Dallas, Texas, United States, 75216
    - VA North Texas Health Care System - Dallas VAMC
  - Dallas, Texas, United States, 75226
    - Baylor Heart and Vascular Institute
  - Edinburg, Texas, United States, 78539
    - Doctors Hospital at Renaissance
  - Fort Worth, Texas, United States, 76164
    - Rockwood Medical Clinic
  - Fort Worth, Texas, United States, 76104
    - Amir Malik Research
  - Fort Worth, Texas, United States, 76104
    - The Medical Group Of Texas
  - Georgetown, Texas, United States, 78626
    - San Gabriel Clinical Research, LLC
  - Houston, Texas, United States, 77030
    - Baylor College of Medicine
  - Houston, Texas, United States, 77081
    - Texas Center for Drug Development, Inc.
  - Houston, Texas, United States, 77058
    - Centex Studies, Inc.
  - Houston, Texas, United States, 77002
    - Spring Clinical Research
  - Houston, Texas, United States, 77024
    - Prime Care Medical Group
  - Houston, Texas, United States, 77002
    - East Texas Cardiology PA
  - Houston, Texas, United States, 77024
    - Med Tech Research, LP
  - Houston, Texas, United States, 77027
    - Associates in Medicine, PA
  - Houston, Texas, United States, 77030
    - Alan S. Hoffman, M.D.
  - Houston, Texas, United States, 77094
    - Private Practice Leadership, LLC
  - Houston, Texas, United States, 77030
    - Investigational Product Shipment Address TO: Investigational Drug Services (IDS),
  - Houston, Texas, United States, 77070
    - Northwest Houston Cardiology
  - Hurst, Texas, United States, 76054
    - Protenium Clinical Research
  - Kerrville, Texas, United States, 78028
    - South Texas Cardiovascular Consultants, PLLC
  - Lubbock, Texas, United States, 79410
    - Caprock Cardiac Center Research Institute Inc.
  - Midland, Texas, United States, 79707
    - Midland Clinical Research Center
  - New Braunfels, Texas, United States, 78130
    - Hill Country Medical Associates
  - North Richland Hills, Texas, United States, 76180
    - North Hills Medical Research, Inc.
  - Palestine, Texas, United States, 75801
    - Grace Research, LLC
  - Pasadena, Texas, United States, 77504
    - Med-Olam Clinical Research
  - Pflugerville, Texas, United States, 78660
    - Austin Institute for Clinical Research, Inc.
  - Pflugerville, Texas, United States, 78660
    - Austin Institute for Clinical Research,Inc.
  - Pharr, Texas, United States, 78577
    - Centex Studies, Inc
  - Plano, Texas, United States, 75024
    - Legacy Heart Center
  - San Antonio, Texas, United States, 78215
    - Sun Research Institute
  - San Antonio, Texas, United States, 78221
    - Southwest Clinic
  - San Antonio, Texas, United States, 78201
    - South Texas Cardiovascular Consultants, PLLC
  - San Antonio, Texas, United States, 78231
    - Victorium Clinical Research
  - San Antonio, Texas, United States, 78249
    - Bandera Family Health Care, LLC
  - Schertz, Texas, United States, 78154
    - Northeast Clinical Research of San Antonio, LLC (NECRSA, LLC)
  - Sugar Land, Texas, United States, 77479
    - Sugar Lakes Family Practice
  - Sugar Land, Texas, United States, 77478
    - IP + Dry ice deliveries Sugar Lakes Family Practice
  - Sugar Land, Texas, United States, 77478
    - Acacia Medical Research Institute, LLC
  - Tomball, Texas, United States, 77375-4536
    - Northwest Houston Heart Center
  - Tomball, Texas, United States, 77375
    - Northwest Heart Center
  - Tomball, Texas, United States, 77375
    - Admin & Storage only:Northwest Heart Center
  - Tomball, Texas, United States, 77375
    - Northwest Houston Clinical Research, PLLC
  - Victoria, Texas, United States, 77901
    - Victoria Heart and Vascular Center, PA
- Utah
  - Bountiful, Utah, United States, 84010
    - Utah Cardiology, PC
  - Layton, Utah, United States, 84041
    - Utah Cardiology, P.C.
  - Ogden, Utah, United States, 84405
    - Paramount Medical Care
  - Orem, Utah, United States, 84058
    - Aspen Clinical Research LLC
  - Provo, Utah, United States, 84604
    - Revere Health
  - Salt Lake City, Utah, United States, 84102
    - Optimum Clinical Research, Inc.
  - Salt Lake City, Utah, United States, 84117
    - Holladay Family Practice
  - Salt Lake City, Utah, United States, 84107
    - Wasatch Clinical Research, LLC
  - Salt Lake City, Utah, United States, 84124
    - Heart Center at St. Mark's Hospital
- Virginia
  - Burke, Virginia, United States, 22015
    - Burke Internal Medicine & Research
  - Burke, Virginia, United States, 22015
    - Clinical Research Institute of Northern Virginia
  - Falls Church, Virginia, United States, 22042
    - Virginia Heart
  - Falls Church, Virginia, United States, 22044
    - Seven Corners Medical Research Center
  - Hopewell, Virginia, United States, 23860
    - Heart Care Associates, P.C.
  - Midlothian, Virginia, United States, 23114
    - Virginia Research Center
  - Richmond, Virginia, United States, 23225
    - Chippenham and Johnston Willis Hospitals, Inc. dba CJW Medical Center
  - Richmond, Virginia, United States, 23225
    - Retreat Cardiology LLC, dba Cardiology Associates of Richmond
  - Roanoke, Virginia, United States, 24014
    - Roanoke Heart Institute
  - Suffolk, Virginia, United States, 23435
    - Hampton Roads Center for Clinical Research
- Washington
  - Burien, Washington, United States, 98166
    - Office of Daniel W. Gottlieb, MD, PS
  - Spokane, Washington, United States, 99202
    - Premier Clinical Research
  - Tacoma, Washington, United States, 98405
    - Universal Research Group, LLC
  - Walla Walla, Washington, United States, 99362
    - Walla Walla Clinic
  - Wenatchee, Washington, United States, 98801
    - Wenatchee Valley Hospital & Clinics
- West Virginia
  - Fairmont, West Virginia, United States, 26554
    - Exemplar Research Inc
- Wisconsin
  - Green Bay, Wisconsin, United States, 54303
    - Prevea Clinic, Inc.
  - Kenosha, Wisconsin, United States, 53142
    - Clinical Investigation Specialists, Inc.
  - Waukesha, Wisconsin, United States, 53188
    - Waukesha Heart Foundation

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Genders Eligible for Study

All

Description

Inclusion Criteria:

Must be on background lipid lowering treatment.
Must be at high risk of a CV event.
Must have an LDL C >/=100 mg/dL (2.6 mmol/L) OR non HDL C >/=130 mg/dL (3.4 mmol/L).

Exclusion Criteria:

Planned coronary (PCI or CABG) or other arterial revascularization.
New York Heart Association Class IV congestive heart failure or left ventricular ejection fraction < 25% by cardiac imaging.
Chronic renal insufficiency with creatinine clearance of <30 ml/min/1.73m^2 by MDRD formula or with end state renal disease on dialysis.
History of hemorrhagic stroke.
Prior exposure to bococizumab or other investigational PCSK9 inhibitor.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: Prevention
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Quadruple

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Placebo Comparator: Placebo Placebo comparator, every 2 weeks, subcutaneous.	Drug: Placebo Placebo comparator, every 2 weeks, subcutaneous. The duration of the treatment period will depend upon reaching the targeted number of adjudicated and confirmed CV outcome events, approximately 3 to 4 years after the entry of first subject into the study.
Experimental: bococizumab (PF-04950615) 150 mg, every 2 weeks, subcutaneous.	Drug: bococizumab (PF-04950615) 150 mg, every 2 weeks, subcutaneous. The duration of the treatment period will depend upon reaching the targeted number of adjudicated and confirmed CV outcome events, approximately 3 to 4 years after the entry of first subject into the study. Other Names: RN316

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Event Rate Per 100 Participant-years for First Occurrence of Major Cardiovascular (CV) Event Time Frame: From baseline until the date of first adjudicated and confirmed occurrence of major CV event (maximum duration: up to 3.4 years)	Event rate per 100 participant-years for first occurrence of major CV event (adjudicated by Adjudication Committee) was reported. Major CV event was defined as any of the following: CV death [defined as sudden cardiac death, fatal myocardial infarction (MI), death due to heart failure, death due to stroke (fatal ischemic stroke or fatal stroke of undetermined etiology), or death due to other CV causes] non-fatal MI, non-fatal stroke, and hospitalization for unstable angina needing urgent revascularization. Event rate was calculated as the number of events per 100 participant-years at risk.	From baseline until the date of first adjudicated and confirmed occurrence of major CV event (maximum duration: up to 3.4 years)

Secondary Outcome Measures

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Pfizer

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

To obtain contact information for a study center near you, click here.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 29, 2013

Primary Completion (Actual)

April 3, 2017

Study Completion (Actual)

April 3, 2017

Study Registration Dates

First Submitted

October 21, 2013

First Submitted That Met QC Criteria

October 28, 2013

First Posted (Estimate)

November 3, 2013

Study Record Updates

Last Update Posted (Actual)

May 1, 2019

Last Update Submitted That Met QC Criteria

April 18, 2019

Last Verified

April 1, 2019

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

B1481038
CV OUTCOMES 2 (Alias Study Number)
2013-002795-41 (EudraCT Number)

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Study Overview

Status

Conditions

Intervention / Treatment

Detailed Description

Study Type

Enrollment (Actual)

Phase

Contacts and Locations

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Genders Eligible for Study

Description

Study Plan

How is the study designed?

Design Details

Number of Arms

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Collaborators and Investigators

Sponsor

Publications and helpful links

General Publications

Helpful Links

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Actual)

Study Completion (Actual)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Estimate)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product

Clinical Trials on Cardiovascular Disease

Clinical Trials on bococizumab (PF-04950615)

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