Denne side blev automatisk oversat, og nøjagtigheden af oversættelsen er ikke garanteret. Der henvises til engelsk version for en kildetekst.

Evalueringen af Bococizumab (PF-04950615; RN316) til at reducere forekomsten af større kardiovaskulære hændelser hos højrisikopersoner (SPIRE-2)

18. april 2019 opdateret af: Pfizer

Fase 3 multicenter, dobbeltblind, randomiseret, placebokontrolleret, parallel gruppeevaluering af effektivitet, sikkerhed og tolerabilitet af Bococizumab (Pf-04950615), til at reducere forekomsten af større kardiovaskulære hændelser hos højrisikopersoner

Denne undersøgelse evaluerer PCSK9-hæmmeren, Bococizumab (PF-04950615;RN316), sammenlignet med placebo, med hensyn til at reducere forekomsten af større kardiovaskulære hændelser, herunder kardiovaskulær død, myokardieinfarkt, slagtilfælde og ustabil angina, der kræver akut revaskularisering hos højrisikopersoner. modtager lipidsænkende baggrundsbehandling og har kolesterollaboratorieværdier på LDL-C >/= 100 mg/dL (2,6 mmol/L) eller non-HDL-C >/= 130 mg/dL (3,4 mmol/L).

Studieoversigt

Status

Afsluttet

Betingelser

Kardiovaskulær sygdom

Intervention / Behandling

Detaljeret beskrivelse

Forsøget blev afsluttet før tid den 1. november 2016 på grund af den nye kliniske profil og det udviklende behandlings- og markedslandskab for lipidsænkende midler. Disse indikerede, at bococizumab sandsynligvis ikke ville give værdi til patienter, læger eller aktionærer. Beslutningen var ikke baseret på en anbefaling fra den uafhængige dataovervågningskomité om at stoppe programmet.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

10564

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Argentina
- - Ciudad Autonoma De B. Aires, Argentina, C1405BUB
    - Cicemo - Consultorio de Investigaciones Clinicas E.M.O. S.R.L.
  - Ciudad Autonoma De Buenos Aires, Argentina, C1405BCK
    - Universidad Maimonides
  - Ciudad Autonoma de B. Aires, Argentina, C1428ART
    - Instituto Cardiovascular de Buenos Aires
  - Ciudad Autonoma de Buenos Aires, Argentina, C1430CKE
    - Centro de Investigacion: AXISMED S.R.L.
  - Cordoba, Argentina, X5003DCE
    - Instituto Médico DAMIC S.R.L.
  - Cordoba, Argentina, X5000BNB
    - ILAIM Instituto Latinoamericano de Investigaciones Medicas
  - Cordoba, Argentina, X5000EPU
    - Clinico Chutro SRL
  - Cordoba, Argentina, X5000EVQ
    - Centro de Investigaciones Clinicas "Instituto del Corazon"
  - Cordoba, Argentina, x5002AOQ
    - Clínica Privada Colombo
  - Cordoba, Argentina, X5006IKK
    - Centro Médico Luquez
  - Cordoba, Argentina, X5008KKF
    - Ipac Caraffa
  - Corrientes, Argentina, 3400
    - Instituto de Cardiologia de Corrientes "Juana Fca. Cabral"
  - Mendoza, Argentina, 5500
    - Hospital Central de Mendoza
  - Salta, Argentina, 4400
    - Cordis S.A.
  - Salta, Argentina, A4406BPF
    - Centro Cardiovascular Salta
  - San Luis, Argentina, D5702JRS
    - Instituto Cardiovascular San Luis A.E.
- Buenos Aires
  - Bahia Blanca, Buenos Aires, Argentina, B8001HXM
    - Hospital Italiano Regional Del Sur
  - Bahia Blanca, Buenos Aires, Argentina, B8000FTD
    - Instituto de Investigaciones Clinicas Bahia Blanca
  - C.a.b.a., Buenos Aires, Argentina, C1119ACN
    - CIPREC - Centro de Investigacion y Prevencion Cardiovascular S.A.
  - Ciudad Autonoma de B. Aires, Buenos Aires, Argentina, C1280AEB
    - Hospital Britanico de Buenos Aires
  - Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, C1425DES
    - Cedic - Consultorios Medicos
  - Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, C1179AAB
    - Investigaciones Medicas IMOBA S.R.L.
  - Coronel Suarez, Buenos Aires, Argentina, B7540GHD
    - Clinica Coronel Suarez S.A.
  - La Plata, Buenos Aires, Argentina, B1902COS
    - Framingham Centro Medico
  - Lanus Este, Buenos Aires, Argentina, B1824KAJ
    - CIMeL CHAHIN CHAHIN S.A.
  - Mar del Plata, Buenos Aires, Argentina, B7600FZN
    - Instituto de Investigaciones Clinicas Mar del Plata
  - Ramos Mejia, Buenos Aires, Argentina, B1704ETD
    - DIM Clinica Privada
  - Zarate, Buenos Aires, Argentina, B2800DGH
    - Instituto de Investigaciones Clínicas Zarate
- C.a.b.a.
  - C.a.b.a, C.a.b.a., Argentina, C1425AGC
    - Consultorios Asociados de Endocrinología e Investigación Clínica Aplicada
- Caba
  - C.a.b.a, Caba, Argentina, C1023AAB
    - Stat Research S.A.
- Cordoba
  - Villa Maria, Cordoba, Argentina, 5901
    - Clinica Privada de Especialidades Medicas
- Mendoza
  - Godoy Cruz, Mendoza, Argentina, M5501ARP
    - CIPADI Centro Integral de Prevención y Atención en Diabetes
- PCIA DE Buenos Aires
  - Ciudadela, PCIA DE Buenos Aires, Argentina, 1702
    - IMEP Instituto Medico Elsa Perez
  - Moron, PCIA DE Buenos Aires, Argentina, B1708CGU
    - Instituto Medico Aguero
- PCIA DE Chaco
  - Resistencia, PCIA DE Chaco, Argentina, H3500CDM
    - Cordis - Instituto del Corazon
- PCIA DE Formosa
  - Formosa, PCIA DE Formosa, Argentina, 3600
    - Hospital de Alta Complejidad "Pte. Juan Domingo Perón"
- PCIA DE Santa FE
  - Santa Fe, PCIA DE Santa FE, Argentina, S3000EOZ
    - Hospital Provincial Dr. Jose Maria Cullen
  - Santa Fe, PCIA DE Santa FE, Argentina, S3000FWO
    - Centro de Investigaciones Clinicas del Litoral S.R.L.
  - Santa Fe, PCIA DE Santa FE, Argentina, S3004CVS
    - Cedir S.A - Centro De Diagnostico Y Rehabilitacion S.A.
- PCIA DE Tucuman
  - San Miguel De Tucuman, PCIA DE Tucuman, Argentina, T4000IFL
    - Centro Modelo de Cardiología
- Pcia. DE Santa FE
  - Rosario, Pcia. DE Santa FE, Argentina, S2000CFK
    - Instituto de Hematologia y Medicina Clinica "Dr. Ruben A. Davoli"
- Provincia DE Santa FE
  - Rosario, Provincia DE Santa FE, Argentina, S2000QID
    - Instituto Medico Ceniclar - Central De Investigaciones Clinicas Argentina - Sanatorio De La Mujer
- Tucuman
  - San Miguel de Tucuman, Tucuman, Argentina, T4000IAF
    - Centro Medico CCBR Tucuman
Australien
- New South Wales
  - Camperdown, New South Wales, Australien, 2050
    - Royal Prince Alfred Hospital
  - Camperdown, New South Wales, Australien, 2050
    - Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders
  - Erina, New South Wales, Australien, 2250
    - Central Coast Neurosciences Research
  - Gosford, New South Wales, Australien, 2250
    - Central Coast Local Health District, Gosford Hospital
  - Maroubra, New South Wales, Australien, 2035
    - Australian Clinical Research Network
- Queensland
  - Chermside, Queensland, Australien, 4032
    - Holy Spirit Northside Private Hospital Limited
  - Herston, Queensland, Australien, 4029
    - Royal Brisbane and Women's Hospital
  - Milton, Queensland, Australien, 4064
    - Core Research Group Pty Ltd
  - Redcliffe, Queensland, Australien, 4020
    - Redcliffe Hospital
  - Sherwood, Queensland, Australien, 4075
    - AusTrials Pty Ltd
  - Southport, Queensland, Australien, 4215
    - Gold Coast University Hospital
- South Australia
  - Ashford, South Australia, Australien, 5035
    - SA Heart
  - Ashford, South Australia, Australien, 5035
    - Adelaide Medical Research
  - Daws Park, South Australia, Australien, 5041
    - Southern Adelaide Diabetes and Endocrine Service
  - Elizabeth Vale, South Australia, Australien, 5112
    - Department of Cardiology, Lyell McEwin Hospital
  - Fullarton, South Australia, Australien, 5063
    - Heart and Vascular Research
- Tasmania
  - Launceston, Tasmania, Australien, 7250
    - Launceston General Hospital
- Victoria
  - Box Hill, Victoria, Australien, 3128
    - Eastern Health - Box Hill Hospital
  - Epping, Victoria, Australien, 3076
    - The Northern Hospital
  - Geelong, Victoria, Australien, 3220
    - Barwon Health-The Geelong Hospital
  - Heidelberg West, Victoria, Australien, 3081
    - Austin Health - Heidelberg Repatriation Hospital
  - Melbourne, Victoria, Australien, 3004
    - Alfred Hospital
- Western Australia
  - Fremantle, Western Australia, Australien, 6160
    - Fremantle Hospital
  - Joondalup, Western Australia, Australien, 6027
    - Joondalup Cardiovascular Trials Foundation Inc.
  - Joondalup, Western Australia, Australien, 6027
    - HPS Pharmacies
Belgien
- - Antwerpen, Belgien, 2020
    - ZNA Campus Middelheim
  - Bonheiden, Belgien, 2820
    - Imeldaziekenhuis Bonheiden
  - Brugge, Belgien, 8000
    - A.Z. St.Jan AV Brugge
  - Brussels, Belgien, 1090
    - University Hospital Brussels - Centrum voor hart- en vaatziekten
  - Brussels, Belgien, 1090
    - University Hospital Brussels- Diabeteskliniek
  - De Pinte, Belgien, 9840
    - Private Practice 'Cardiovascular Detection Center'
  - Genk, Belgien, 3600
    - ZOL Campus Sint-Jan
  - Gent, Belgien, 9000
    - AZ Maria Middelares
  - Gilly, Belgien, 6060
    - Grand Hopital de Charleroi, Site St-Joseph
  - Hasselt, Belgien, 3500
    - Jessa Ziekenhuis
  - Hasselt, Belgien, 3500
    - Hygeia
  - Heusden-Zolder, Belgien, 3550
    - Sint-Franciskusziekenhuis
  - Huy, Belgien, 4500
    - Centre Hospitalier Regional de Huy
  - Ieper, Belgien, 8900
    - Jan Yperman Ziekenhuis, Cardiology
  - La Louviere (Haine-Saint-Paul), Belgien, 7100
    - Centre Hospitalier de Jolimont - Lobbes
  - La Louviere (Haine-Saint-Paul), Belgien, 7100
    - Centre Hospitalier de Jolimont-Lobbes
  - Leuven, Belgien, 3000
    - University Hospitals Leuven
  - Leuven, Belgien, 3000
    - University hospitals Leuven - Neurology department
  - Liege, Belgien, 4000
    - Centre Hospitalier Universitaire (CHU) De Liège
  - Linkebeek, Belgien, 1630
    - Huisartsenpraktijk Medilink
  - Massemen, Belgien, 9230
    - Huisartsenpraktijk Luc Capiau
  - Mons, Belgien, 7000
    - C.H.U. Ambroise Paré
  - Overpelt, Belgien, 3900
    - Mariaziekenhuis vzw
  - Tienen, Belgien, 3300
    - Dr. Luc De Wolf - Private Practice
- Antwerp
  - Mechelen, Antwerp, Belgien, 2800
    - Az Sint-Maarten
- Antwerpen
  - Brasschaat, Antwerpen, Belgien, 2930
    - VZW Algemeen Ziekenhuis KLINA
- Oost-vlaanderen
  - Aalst, Oost-vlaanderen, Belgien, 9300
    - Algemeen Stedelijk Ziekenhuis
  - Dendermonde, Oost-vlaanderen, Belgien, 9200
    - AZ Sint Blasius
  - Gent, Oost-vlaanderen, Belgien, 9000
    - AZ Sint Lucas Gent
  - Gent, Oost-vlaanderen, Belgien, 9000
    - Universitair Ziekenhuis Gent
  - Ronse, Oost-vlaanderen, Belgien, 9600
    - AZ Glorieux
  - Sint-Niklaas, Oost-vlaanderen, Belgien, 9100
    - AZ Nikolaas, Campus Moerland
- West-vlaanderen
  - Kortrijk, West-vlaanderen, Belgien, 8500
    - AZ Groeninge-Campus Loofstraat
  - Oostende, West-vlaanderen, Belgien, 8400
    - AZ Damiaan
Brasilien
- - Minas Gerais, Brasilien, 30150-240
    - CARDSEARCH/CARDRESEARCH - Cardiologia Assistencial e de Pesquisa LTDA
  - Sao Paulo, Brasilien, 01244-030
    - CPClin- Centro de Pesquisas Clinicas Ltda./Clinica Dr. Freddy Goldberg Eliaschewitz
  - Sao Paulo, Brasilien, 01327-010
    - FGM-Clinica Paulista de Doencas Cardiovasculares
  - Sao Paulo, Brasilien, 04266-010
    - CEPIC - Centro Paulista de Investigacao Clinica e Servicos Medicos Ltda
- BA
  - Salvador, BA, Brasilien, 41810-010
    - Fundacao Bahiana de Cardiologia
  - Salvador, BA, Brasilien, 41810-011
    - HBA S/A ASSISTENCIA MEDICA E HOSPITALAR-Hospital da Bahia
- CE
  - Fortaleza, CE, Brasilien, 60430-140
    - Centro de Pesquisas em Diabetes e Doencas Endocrino-Metabolicas Ltda
- Indiana
  - Indianapolis, Indiana, Brasilien, 46214-2985
    - Covance Central Laboratory Services
- Minas Gerais
  - Belo Horizonte, Minas Gerais, Brasilien, 30150-240
    - CARDSEARCH/CARDRESEARCH - Cardiologia Assistencial e de Pesquisa LTDA
- PA
  - Belem, PA, Brasilien, 66073-000
    - Universidade Federal do Para - Hospital Universitario Joao de Barros Barreto
- PE
  - Recife, PE, Brasilien, 52020-010
    - Centro de Pesquisas Médicas Básica e Clínica Ltda
- PR
  - Campina Grande do Sul, PR, Brasilien, 83430-000
    - Sociedade Hospitalar Angelina Caron/Hospital e Maternidade Angelina Caron
  - Curitiba, PR, Brasilien, 80045-170
    - Quanta Diagnostico e Terapia / Medicina Nuclear Alto da XV
  - Curitiba, PR, Brasilien, 80010-030
    - Hospital Santa Casa de Curitiba
- Parana
  - Curitiba, Parana, Brasilien, 80730-150
    - Núcleo de Pesquisa Clinica
- Pernambuco
  - Recife, Pernambuco, Brasilien, 52051-380
    - Hospital Agamenon Magalhaes
- RIO Grande DO SUL
  - Canoas, RIO Grande DO SUL, Brasilien, 92425-055
    - Hospital Universitario - Associacao Educadora Sao Carlos - AESC
  - Porto Alegre, RIO Grande DO SUL, Brasilien, 90020-090
    - Irmandade Santa Casa de Misericordia de Porto Alegre
  - Porto Alegre, RIO Grande DO SUL, Brasilien, 90110-270
    - Hospital Mae de Deus/Associacao Educadora Sao Carlos AESC / IMV - Instituto de Medicina Vascular
  - Porto Alegre, RIO Grande DO SUL, Brasilien, 90620-001
    - Instituto de Cardiologia do Rio Grande do Sul / Fundação Universitária de Cardiologia
  - Porto Alegre, RIO Grande DO SUL, Brasilien, 90840-440
    - Hospital Mae de Deus - Instituto do Cancer
  - Porto Alegre, RIO Grande DO SUL, Brasilien, 90840-440
    - Hospital Mae de Deus-Associacao Educadora de Sao Carlos-AESC/IMV - Instituto de Medicina Vascular
  - Porto Alegre, RIO Grande DO SUL, Brasilien, 90840-440
    - Mae de Deus - Centro de Oncologia Radioterapica (COR)
- RJ
  - Rio de Janeiro, RJ, Brasilien, 22271-100
    - CCBR Brasil - Centro de Pesquisa e Analises Clinicas LTDA
- SAO Paulo
  - Campinas, SAO Paulo, Brasilien, 13010-001
    - Loema Medicina e Bem Estar- Centro Especializado em Cardiologia Ltda.
  - Sao Jose do Rio Preto, SAO Paulo, Brasilien, 15015210
    - IMC - Instituto de Molestias Cardiovasculares/Equipamentos Cardiovasculares Rio Preto Ltda
- SP
  - Campinas, SP, Brasilien, 13087-567
    - CAEP - Centro Avancado de Estudos e Pesquisas Ltda.
  - Sao Paulo, SP, Brasilien, 05403-010
    - Hospital Das Clinicas Da Faculdade De Medicina Da Universidade De Sao Paulo (Hc-Fmusp)
- Santa Catarina
  - Blumenau, Santa Catarina, Brasilien, 89010-906
    - Hospital Santa Isabel
Canada
- - Quebec, Canada, G1V 4W2
    - Clinique des maladies lipidiques de Quebec
  - Quebec, Canada, G1G 3Y8
    - Recherche Clinique Sigma inc
- Alberta
  - Calgary, Alberta, Canada, T2H 2G4
    - LMC Diabetes & Endocrinology (Calgary)
  - Calgary, Alberta, Canada, T2N 4Z6
    - Foothills Hospital/University of Calgary
  - Calgary, Alberta, Canada, T2V 4J2
    - Nanji Professional Corporation
- British Columbia
  - Kelowna, British Columbia, Canada, V1Y 1V6
    - The Medical Arts Health Research Group
  - Kelowna, British Columbia, Canada, VlY 1V6
    - Kelowna Cardiology Associates
  - Surrey, British Columbia, Canada, V3V 0C6
    - SMH Cardiology Clinical Trials
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Raymond Dong Inc.
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Stephen S. Cheung Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Dante E. Manyari Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Stephanie Au, Inc.
  - Surrey, British Columbia, Canada, V3W 3C3
    - Dr. Kapil M. Bhagirath Medical Services Corporation
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Richard Bon Inc. & Dr. Adam Yeung Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Stephen Pearce Inc. & Dr. Peter K.H. Tan Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - SMH Cardiology Clinical Trials Inc
  - Surrey, British Columbia, Canada, V3V OC6
    - Dr. Adam Yeung Inc.
  - Surrey, British Columbia, Canada, V3V OC6
    - Dr. Michael Kanakos Inc.
  - Surrey, British Columbia, Canada, V3VOC6
    - Dr. Stephen S. Cheung Inc.
  - Victoria, British Columbia, Canada, V8R 4R2
    - Victoria Heart Institute Foundation
  - Victoria, British Columbia, Canada, V8T 5G4
    - Discovery Clinical Services Ltd.
- Manitoba
  - Winnipeg, Manitoba, Canada, R2H 2A6
    - St. Boniface Hospital
- NF
  - St. John's, NF, Canada, A1B 3V6
    - Health Sciences Centre
  - St. John's, NF, Canada, A1B3V6
    - Health Science Centre
- New Brunswick
  - Moncton, New Brunswick, Canada, E1G 1A7
    - G.A. Research Associates Ltd.
  - Saint John, New Brunswick, Canada, E2L 4L2
    - Cardiology Research Associates of New Brunswick
- Ontario
  - Brampton, Ontario, Canada, L6S 0C9
    - LMC Diabetes & Endocrinology (Brampton)
  - Burlington, Ontario, Canada, L7M 4Y1
    - JBN Medical Diagnostic Services Inc.
  - Burlington, Ontario, Canada, L7M 4Y1
    - Aviva Clinical Trial Group Inc.
  - Burlington, Ontario, Canada, L7R 4E2
    - Philippe R. Beaudry Medicine Professional Corporation
  - Cambridge, Ontario, Canada, N1R 6V6
    - Cambridge Cardiac Care Centre
  - Cambridge, Ontario, Canada, N1R 7R1
    - Vizel Cardiac Research - Saul Vizel Professional Medicine Corporation
  - Collingwood, Ontario, Canada, L9Y 1W3
    - Moran Medical Centre
  - Fort Erie, Ontario, Canada, L2A 1Z3
    - C & L Research
  - Hamilton, Ontario, Canada, L8K 3P3
    - Parkdale Medical Centre
  - London, Ontario, Canada, N6G 2V2
    - Stroke Prevention & Atherosclerosis Research Centre (SPARC)
  - London, Ontario, Canada, N6G2Ml
    - Western University - WCPHFM
  - Markham, Ontario, Canada, L6B 0P9
    - LMC Diabetes & Endocrinology (Markham)
  - Newmarket, Ontario, Canada, L3Y 8C3
    - Newmarket Cardiology Research Group
  - Oakville, Ontario, Canada, L6M 1M1
    - LMC Clinical Research Inc. (Oakville)
  - Oshawa, Ontario, Canada, L1J 2K1
    - The Office of Dr. James Cha
  - Peterborough, Ontario, Canada, K9J 0B2
    - Kawartha Cardiology Clinical Trials
  - Sarnia, Ontario, Canada, N7T 4X3
    - London Road Diagnostic Clinic and Medical Centre
  - Sarnia, Ontario, Canada, N7T 4X3
    - Sarnia Institute of Clinical Research
  - Scarborough, Ontario, Canada, M1E 5E9
    - Scarborough Cardiology Research Associates Inc.
  - Smiths Falls, Ontario, Canada, K7A 4W8
    - Canadian Centre for Research on Diabetes
  - Sudbury, Ontario, Canada, P3E 2N8
    - Brian Y.L. Wong Medicine Professional Corporation
  - Thornhill, Ontario, Canada, L4J 8L7
    - Lmc Diabetes & Endocrinology (Thornhill)
  - Toronto, Ontario, Canada, M9V 4B4
    - Dr. Anil K. Gupta Medicine Professional Corporation
  - Toronto, Ontario, Canada, M3J 2C5
    - Canadian Phase Onward, Inc.
  - Toronto, Ontario, Canada, M3J 1N2
    - JJ Dig Research Ltd
  - Toronto, Ontario, Canada, M4G 3E8
    - Lmc Diabetes & Endocrinology (Bayview)
  - Waterloo, Ontario, Canada, N2T 0C1
    - Dr. Mohan Babapulle Medicine Professional Cooperation
  - Weston, Ontario, Canada, M9N 1W4
    - Dr. Louis Yao, MD Office of
- Quebec
  - Chicoutimi, Quebec, Canada, G7H 7K9
    - Ecogene-21
  - Chicoutimi, Quebec, Canada, G7H 7Y8
    - Q & T Research Chicoutimi
  - Gatineau, Quebec, Canada, J8Y 6S8
    - Q&T Recherche Outaouais Inc.
  - Mirabel, Quebec, Canada, J7J 2K8
    - Omnispec Recherche Clinique Inc.
  - Montreal, Quebec, Canada, H1T 1C8
    - Montreal Heart Institute
  - Montreal, Quebec, Canada, H2Y 1S1
    - Diex Research Montreal, Inc.
  - Sherbrooke, Quebec, Canada, J1G 2E8
    - Centre Hospitalier Universitaire de Sherbrooke - Hotel-Dieu
  - St-Charles-Borromee, Quebec, Canada, J6E 6J2
    - Centre integre de sante et de services sociaux de Lanaudiere (CISSSL)
  - St-Georges, Beauce, Quebec, Canada, G5Y 4T8
    - Centre Integre de Sante et de services sociaux de Chaudiere-Appalaches (CISSA-CA) -
  - St-Jerome, Quebec, Canada, J7Z 5T3
    - CISSS des Laurentides-Point de Service de St-Jerome- Comite d'ethique de la recherche
  - St-Jerome, Quebec, Canada, J7Z 5T3
    - St-Jerome Medical Research Inc.
  - Trois-Rivieres, Quebec, Canada, G8T 7A1
    - C.I.C. Mauricie inc.
  - Ville Saint-Laurent, Quebec, Canada, H4T 1Z9
    - LMC Clinical Research Inc. (Montreal)
Chile
- - Puerto Varas, Chile, 5550170
    - Quantum Research
  - Santiago, Chile, 8053095
    - Hospital y CRS El Pino
- Metropolitana
  - Providencia Santiago, Metropolitana, Chile, 7500710
    - Biomedica Research Group
  - Santiago, Metropolitana, Chile, 7500021
    - CICAB
  - Santiago, Metropolitana, Chile, 7500739
    - SMOLAM
  - Santiago, Metropolitana, Chile, 8207257
    - Complejo Asitencial Dr. Sotero del Rio
- Region DE LA Araucania
  - Temuco, Region DE LA Araucania, Chile, 4781156
    - Centro de Investigacion Clinica del Sur
- Region DE LOS Lagos
  - Osorno, Region DE LOS Lagos, Chile, 5311092
    - Corporacion de Beneficencia Osorno
- Region Metropolitana
  - Santiago, Region Metropolitana, Chile, 7500710
    - Servicios Medicos Godoy
Colombia
- Antioquia
  - Medellin, Antioquia, Colombia, 00000
    - Hospital Pablo Tobon Uribe
  - Medellin, Antioquia, Colombia
    - Centro de Investigacion Clinica Avanzada y Multidisciplinaria CICLAM
  - Medellin, Antioquia, Colombia, 50012
    - Rodrigo Botero S.A.S
  - Medellin, Antioquia, Colombia
    - Centro de Medicina del Ejercicio y Rehabilitacion Cardiaca S.A. CEMDE S.A.
- Atlantico
  - Barranquila, Atlantico, Colombia
    - Clinica de la Costa Ltda
  - Barranquilla, Atlantico, Colombia, 80020
    - Centro Cientifico Asistencial Jose Luis Accini S.A.S.
  - Barranquilla, Atlantico, Colombia
    - Fundacion del Caribe para la Investigacion Biomedica - Fundacion BIOS
  - Barranquilla, Atlantico, Colombia, 80020
    - Corazon IPS S.A.S.
  - Barranquilla, Atlantico, Colombia
    - Corozan Ips Sas
- Bolivar
  - Cartagena, Bolivar, Colombia
    - Centro de Diagnostico Cardiologico LTDA.
- Caldas
  - Manizales, Caldas, Colombia
    - Asociacion IPS Medicos Internistas de Caldas
- Cundinamarca
  - Bogota D.C, Cundinamarca, Colombia, 110221
    - Dexadiab Servicios Medicos LTDA
  - Bogota D.C, Cundinamarca, Colombia, 111211
    - Caja de Compensacion Familiar CAFAM, Sede Centro de Atencion en Salud CAFAM FLORESTA
  - Bogota D.C, Cundinamarca, Colombia
    - Hospital Universitario San Ignacio
  - Bogota D.C, Cundinamarca, Colombia
    - Instituto de Investigacion Endocrinologia y Prevencion Metabolica - ENDOCARE LTDA.
  - Bogota D.C., Cundinamarca, Colombia, 110911
    - Medplus Medicina Prepagada S.A.
  - Bogota D.C., Cundinamarca, Colombia
    - Solano & Terront Servicios Medicos Ltda-Establecimiento Comercial UNIENDO
- Santander
  - Bucaramanga, Santander, Colombia
    - Instituto del Corazon de Bucaramanga S.A.
  - Floridablanca, Santander, Colombia
    - Fundación Cardiovacular de Colombia - Instituto del Corazón de Floridablanca
- Valle DEL Cauca
  - Cali, Valle DEL Cauca, Colombia, 760001
    - Fundación Reina Isabel
Danmark
- - Aabenraa, Danmark, 6200
    - Sygehus Sonderjylland Aabenraa
  - Aalborg, Danmark, 9000
    - Aalborg Universitetshospital, Lipidklinikken
  - Aalborg, Danmark, 9000
    - CCBR Aalborg
  - Aarhus, Danmark, 8200
    - Aarhus Universitetshospital Skejby, Hjertesygdomme ¿ Klinisk Forskning
  - Aarhus N, Danmark, 8250
    - Aarhus Universitetshospital
  - Ballerup, Danmark, 2750
    - CCBR Ballerup
  - Copenhagen NV, Danmark, 2400
    - Bispebjerg Og Frederiksberg Hospital
  - Copenhagen Oe, Danmark, 2100
    - Rigshospitalet
  - Esbjerg, Danmark, 6700
    - Sydvestjysk Sygehus
  - Frederiksberg, Danmark, 2000
    - Frederiksberg Hospital
  - Glostrup, Danmark, 2600
    - Glostrup Hospital
  - Herlev, Danmark, 2730
    - Herlev Universitetshospital, Kardiologisk afdeling S
  - Herning, Danmark, 7400
    - Regionshospitalet Herning
  - Hillerod, Danmark, 3400
    - Hillerod Hospital
  - Hvidovre, Danmark, 2650
    - Hvidovre Universitetshospital, Hjerte-lungemedicinsk afdeling
  - Kobenhavn S., Danmark, 2300
    - Amager Hospital
  - Koge, Danmark, 4600
    - Region Sjaelland Sygehus Nord, Koge Sygehus
  - Kolding, Danmark, 6000
    - Kolding Sygehus
  - Naestved, Danmark, 4700
    - Region Sjaelland Naestved Sygehus
  - Nykobing F., Danmark, 4800
    - Nykobing F. Sygehus-Medicinsk afdeling
  - Randers, Danmark, 8930
    - Regionshospitalet Randers
  - Silkeborg, Danmark, 8600
    - Regionshospitalet Silkeborg, Hjerte Projektkontor
  - Slagelse, Danmark, 4200
    - Slagelse Sygehus
  - Svendborg, Danmark, 5700
    - Svendborg Sygehus
  - Vejle, Danmark, DK 7100
    - CCBR Vejle
  - Viborg, Danmark, 8800
    - Hospitalsenheden Midt, Regionshospital Viborg
Den Russiske Føderation
- - Chelyabinsk, Den Russiske Føderation, 454047
    - Municipal Budgetary State Healthcare Institution "City Clinical Hospital #6"
  - Chelyabinsk, Den Russiske Føderation, 454092
    - Non-State Institution of Healthcare
  - Chelyabinsk, Den Russiske Føderation, 454136
    - State Budgetary Healthcare Institution ¿Region Clinical Hospital #3¿
  - Ekaterinburg, Den Russiske Føderation, 620039
    - Municipal Autonomous Institution "City Clinical Hospital #14"
  - Ivanovo, Den Russiske Føderation, 153012
    - Regional Budgetary Healthcare Institution "Cardiology Dispensary"
  - Kaluga, Den Russiske Føderation, 428007
    - State Budgetary Institution of Healthcare of Kaluga Region "Kaluga Regional Hospital"
  - Kazan, Den Russiske Føderation, 420012
    - Federal State Budgetary Educational Institution of Higher Education "Kazan State Medical University"
  - Kazan, Den Russiske Føderation, 420064
    - State Autonomous Healthcare Institution "Republic Clinical Hospital"
  - Kemerovo, Den Russiske Føderation, 650000
    - "SAHI of Kemerovo ""Regional Clinical Hospital of Emergency Medical Care n.a. M.A Podgorbunsky """
  - Kemerovo, Den Russiske Føderation, 650000
    - Municipal Budgetary Institution of Healthcare Municipal Clinical Hospital #3 n.a. M.A. Podgorbunsky
  - Kemerovo, Den Russiske Føderation, 650002
    - FSBI "Research institute of complex problems of cardio-vascular diseases" of
  - Kemerovo, Den Russiske Føderation, 650099
    - FSHI "Medical and Sanitary Unit of the Ministry of Internal Affairs of Russia across
  - Kirov, Den Russiske Føderation, 610014
    - Kirov Regional State Budgetary Healthcare Institution "Kirov City Clinical Hospital #1"
  - Kursk, Den Russiske Føderation, 305035
    - Regional Budgetary Healthcare Institution "Kursk City Clinical Emergency Hospital"
  - Moscow, Den Russiske Føderation, 109388
    - Non-State Institution of Healthcare "Central Clinical Hospital #6 OAO "RZhD"
  - Moscow, Den Russiske Føderation, 121359
    - Federal State Budgetary Institution "Central Clinical Hospital with Polyclinic"
  - Moscow, Den Russiske Føderation, 125284
    - Moscow State Healthcare Institution "City clinical hospital n.a. S.P.Botkin"
  - Moscow, Den Russiske Føderation, 111539
    - SBHI Moscow city "City Clinical Hospital #15 n.a. O.M. Filatova" of Moscow Healthcare Department
  - Moscow, Den Russiske Føderation, 121552
    - "Federal State Budgetary Institution "Russian Cardiology Research And Production Complex" Of
  - Moscow, Den Russiske Føderation, 127644
    - State Budget Institution of Healthcare (SBIH) of Moscow "City Clinical Hospital #81
  - Moscow, Den Russiske Føderation, 129090
    - Federal State Budget Institution "Out-patient Clinic #3" of Russian Federation, President's
  - Murmansk, Den Russiske Føderation, 183047
    - State Regional Budgetary Healthcare Institution
  - Nizhniy Novgorod, Den Russiske Føderation, 603076
    - State Budgetary Healthcare Institution of Nizhegorodskaya Region
  - Novosibirsk, Den Russiske Føderation, 630099
    - "Reafan" LLC
  - Novosibirsk, Den Russiske Føderation, 630102
    - Municipal Budgetary Institution of Healthcare of Novosibirsk
  - Novosibirsk, Den Russiske Føderation, 630102
    - State Budgetary Institution of Healthcare of Novosibirsk region City Clinical Hospital of Emergency
  - Novosibirsk, Den Russiske Føderation, 630089
    - Federal State Budgetary Institution "Research Institute of Therapy and Preventive Medicine"
  - Penza, Den Russiske Føderation, 440026
    - State Budgetary Healthcare Institution (SBHI) N.N. Burdenko Regional Clinical Hospital of Penza
  - Pushkin, Den Russiske Føderation, 196601
    - SBHI of Saint-Petersburg "City Hospital # 38 n.a. N.A. Semashko"
  - Rostov-on-Don, Den Russiske Føderation, 344022
    - State Budgetary Educational Institution of Higher Professional Education
  - Rostov-on-Don, Den Russiske Føderation, 344068
    - State Budgetary Educational Institution of Higher Professional Education
  - Ryazan, Den Russiske Føderation, 390039
    - State Budgetary Institution "Ryazan Regional Clinical Hospital"
  - Saint Petersburg, Den Russiske Føderation, 194354
    - Limited Liability Company "Reavita"
  - Saint Petersburg, Den Russiske Føderation, 196084
    - LLC "Institution of medical studies"
  - Saint Petersburg, Den Russiske Føderation, 197341
    - Federal State Budgetary Institution "Federal Almazov Medical Research Centre" of
  - Saint-Petersberg, Den Russiske Føderation, 191186
    - Limited Liability Company International Medical Centre SOGAZ
  - Saint-Petersburg, Den Russiske Føderation, 192148
    - Saint-Petersburg State Budgetary Institution of Healthcare "City Hospital #23"
  - Saint-Petersburg, Den Russiske Føderation, 193312
    - Saint-Petersburg State Budgetary Healthcare Institution "City Alexandrovskaya Hospital"
  - Saint-Petersburg, Den Russiske Føderation, 197022
    - SBEI of HPE "First Pavlov State Medical University of St. Petersburg" of the MoH of the RF
  - Saint-Petersburg, Den Russiske Føderation, 197110
    - Federal State Budgetary Institution "Advisory Diagnostic Center and Polyclinic"
  - Saint-Petersburg, Den Russiske Føderation, 198205
    - Saint-Petersburg State Budgetary Healthcare Institution "City Hospital #15"
  - Saint-Petersburg, Den Russiske Føderation, 196247
    - Saint-Petersburg State Budgetary Institution of Healthcare "City Hospital #26"
  - Samara, Den Russiske Føderation, 443070
    - State Budgetary Healthcare Institution "Samara Regional Clinical Cardiology Dispensary"
  - Saratov, Den Russiske Føderation, 410053
    - State Institution of Healthcare "Regional Clinical Hospital"
  - Saratov, Den Russiske Føderation, 410039
    - MHI "City Clinical Hospital 12"of the Healthcare Committee of
  - St. Petersburg, Den Russiske Føderation, 197022
    - Federal State Budgetary Educational Institution of Higher Education "Academician I.P. Pavlov First
  - Tomsk, Den Russiske Føderation, 634009
    - Tyumen Cardiology Research Center-branch of the Tomsk NRMC
  - Tomsk, Den Russiske Føderation, 634050
    - State Budgetary Educational Institution of Highest Professional Education
  - Tyumen, Den Russiske Føderation, 625000
    - State Autonomous Healthcare Institution of Tyumen region "Scientific-Practical Medical Center"
  - Tyumen, Den Russiske Føderation, 625026
    - "Tyumen Cardiology Center" Affiliate of the FSBSI "Scientific and Research Institution of Cardiology
  - Yaroslavl, Den Russiske Føderation, 150003
    - State Autonomous Healthcare Institution Of Yaroslavl Region
  - Yaroslavl, Den Russiske Føderation, 150023
    - State Budgetary Healthcare Institution of Yaroslavl Region "Clinical Hospital No. 10"
  - Yaroslavl, Den Russiske Føderation, 150030
    - State Healthcare Institution of Yaroslavl Region "Clinical Hospital #8"
  - Yaroslavl, Den Russiske Føderation, 150003
    - State Autonomous Healthcare Institution of Yaroslavl region Clinical Emergency Hospital n.a..N.V.So
  - Yaroslavl, Den Russiske Føderation, 150010
    - FSBEI of HE "Yaroslavl State Medical University" MH of the Russian Federation based on Clinical
- Krasnodar Region
  - Krasnodar, Krasnodar Region, Den Russiske Føderation, 350086
    - State Budgetary Healthcare Institution "Research Institution - Regional Clinical Hospital #1
- Moscow Region
  - Lubertsy, Moscow Region, Den Russiske Føderation, 140006
    - State Budgetary Healthcare Institution of Moscow Region "Lubertsy Regional Hospital #2"
  - Troitsk, Moscow Region, Den Russiske Føderation, 142190
    - Federal State Budgetary Institution of Healthcare Hospital of Russian Academy of Sciences
- Sankt-peterburg
  - St. Petersburg, Sankt-peterburg, Den Russiske Føderation, 197022
    - 1st Pavlov State Medical University of St. Petersburg
- Sestroretsk
  - St. Petersburg, Sestroretsk, Den Russiske Føderation, 197706
    - Saint Petersburg State Budgetary Institution of Healthcare
- Tatarstan Republic
  - Kazan, Tatarstan Republic, Den Russiske Føderation, 420033
    - FSBEI of HE Kazan State Medical University on the base of SBHI Clinical Hospital No.2
Det Forenede Kongerige
- - Barnet, Det Forenede Kongerige, EN5 3DJ
    - Royal Free London NHS Foundation Trust
  - Birmingham, Det Forenede Kongerige, B6 6BB
    - Laurie Pike Health Centre
  - Birmingham, Det Forenede Kongerige, B9 5SS
    - Heart of England NHS Foundation Trust, Dept. of Clinical Biochemistry & Immunology
  - Cardiff, Det Forenede Kongerige, CF14 5GJ
    - Synexus Wales Clinical Research Centre
  - Chesterfield, Det Forenede Kongerige, S404AA
    - Ashgate Medical Practice
  - East Sussex, Det Forenede Kongerige, TN39 4SP
    - Little Common Surgery
  - East Sussex, Det Forenede Kongerige, TN40 1JJ
    - Sea Road Surgery
  - Ely, Det Forenede Kongerige, CB7 5JD
    - Staploe Medical Centre
  - Glasgow, Det Forenede Kongerige, G69 7AD
    - McGlone Practice - Ballieston Health Centre
  - Glosgow, Det Forenede Kongerige, G51 4TF
    - The Queen Elizabeth University Hospital- NHS Greater Glasgow and Clyde
  - Hinckley, Det Forenede Kongerige, LE10 2SE
    - Burbage Surgery
  - Liverpool, Det Forenede Kongerige, L7 8XP
    - The Royal Liverpool and Broadgreen -University Hospitals NHS
  - London, Det Forenede Kongerige, NW3 2QG
    - Royal Free Hospital
  - London, Det Forenede Kongerige, EC1M 6BQ
    - Barts Health NHS Trust
  - London, Det Forenede Kongerige, W12 OHS
    - Peart-Rose Research Unit, Hammersmith Hospital, Imperial College NHS Trust
  - Middlesbrough, Det Forenede Kongerige, TS4 3BW
    - The Red Porto cabin, The James Cook University Hospital
  - Newport, Det Forenede Kongerige, PO30 5TG
    - St Mary's Hospital
  - Peterborough, Det Forenede Kongerige, PE8 6PL
    - Wansford and Kings Cliffe Practice
  - Rothwell, Northants, Det Forenede Kongerige, NN14 6JQ
    - Rothwell and Desborough Healthcare Group
  - Swansea, Det Forenede Kongerige, SA2 8PP
    - Abertawe Bro Morgannwg University Local Health Board Joint
  - Worthing, Det Forenede Kongerige, BN11 2DH
    - Western Sussex Hosptials NHS Trust
  - York, Det Forenede Kongerige, YO30 6AE
    - York Medical Group
  - York, Det Forenede Kongerige, YO32 5UA
    - Strensall Healthcare Centre
- Berkshire
  - Reading, Berkshire, Det Forenede Kongerige, RG2 0TG
    - Synexus Thames Valley Clinical Research Centre
- Cambridgeshire
  - Peterborough, Cambridgeshire, Det Forenede Kongerige, PE3 9GZ
    - Peterborough and Stamford Hospitals NHS Foundation Trust
- Cornwall
  - St Austell, Cornwall, Det Forenede Kongerige, PL26 7RL
    - Brannel Surgery
- Essex
  - Romford, Essex, Det Forenede Kongerige, RM7 0AG
    - Queens Hospital
- Greater Manchester
  - Manchester, Greater Manchester, Det Forenede Kongerige, M15 6SX
    - Synexus Manchester Clinical Research Centre-Manchester Science Park
  - Oldham, Greater Manchester, Det Forenede Kongerige, OL1 2JH
    - Royal Oldham Hospital
  - Salford, Greater Manchester, Det Forenede Kongerige, M6 8HD
    - Salford Royal NHS Foundation Trust
- Hertfordshire
  - Stevenage, Hertfordshire, Det Forenede Kongerige, SG1 4AB
    - Lister Hospital
  - Welwyn Garden City, Hertfordshire, Det Forenede Kongerige, AL7 4HQ
    - Queen Elizabeth II Hospital, East and North Hertfordshire NHS Trust
- Kent
  - Gillingham, Kent, Det Forenede Kongerige, ME7 5NY
    - Medway Maritime Hospital
- Lanarkshire
  - Glasgow, Lanarkshire, Det Forenede Kongerige, G20 0SP
    - Synexus Scotland Clinical Research Centre
- Lancashire
  - Bolton, Lancashire, Det Forenede Kongerige, BL4 0JR
    - Bolton NHS Foundation Trust
  - Chorley, Lancashire, Det Forenede Kongerige, PR7 7NA
    - Synexus Lancashire Clinical Research Centre
  - Layton, Blackpool, Lancashire, Det Forenede Kongerige, FY3 7EN
    - Layton Medical Centre
- Merseyside
  - Liverpool, Merseyside, Det Forenede Kongerige, L22 0LG
    - Synexus Merseyside Clinical Research Centre
- North Yorkshire
  - Whitby, North Yorkshire, Det Forenede Kongerige, YO21 1SD
    - Whitby Group Practice
- Northants
  - Wellingborough, Northants, Det Forenede Kongerige, NN84RW
    - Albany House Medical Centre
- Northern Ireland
  - Portadown, Northern Ireland, Det Forenede Kongerige, BT63 5QQ
    - Southern Health & Social Care Trust, Craigavon Area Hospital
- Northumberland
  - Hexham, Northumberland, Det Forenede Kongerige, NE46 1QJ
    - Synexus North East Clinical Research Centre - Hexham General Hospital
- South Yorkshire
  - Doncaster, South Yorkshire, Det Forenede Kongerige, DN9 2HY
    - South Axholme Practice
  - Manchester, South Yorkshire, Det Forenede Kongerige, M13 9WL
    - Central Manchester University Hospitals NHS Foundation Trust
- Surrey
  - Addlestone, Surrey, Det Forenede Kongerige, KT15 2BH
    - The Crouch Oak Family Practice
- WEST Midlands
  - Birmingham, WEST Midlands, Det Forenede Kongerige, B15 2SQ
    - Synexus Midlands Clinical Research Centre
  - Birmingham, WEST Midlands, Det Forenede Kongerige, B18 7QH
    - City Hospital
- WEST Wales
  - Llanelli, WEST Wales, Det Forenede Kongerige, SF14 8QF
    - Prince Philip Hospital
- Wales
  - Cardiff, Wales, Det Forenede Kongerige, CF5 4AD
    - Ely Bridge Surgery
Finland
- - Hameenlinna, Finland, 13100
    - Linnan Klinikka Oy
  - Helsinki, Finland, 00290
    - Helsinki University Central Hospital
  - Helsinki, Finland, FI-00290
    - Helsingin yliopistollinen keskussairaala, Sisaetaudit ja kuntoutus, Biomedicum 2U
  - Helsinki, Finland, 00260
    - Mehiläinen Töölö
  - Joensuu, Finland, 80100
    - Ita-Suomen laakarikeskus Oy
  - Jyvaskyla, Finland, 40620
    - StudyCor Oy
  - Kerava, Finland, 04200
    - Laeaekaerikeskus Aava Kerava
  - Kinkomaa, Finland, 40930
    - Menoa oy
  - Kokkola, Finland, 67200
    - Kokkolan Keskussairaala
  - Kotka, Finland, 48600
    - Mewell liikuntaklinikka
  - Kuopio, Finland, 70100
    - Terveystalo Kuopio
  - Kuopio, Finland, 70100
    - Itae-Suomen Laeaekaeritalo Oy
  - Oulu, Finland, 90220
    - Oulu University Hospital
  - Oulu, Finland, 90100
    - Oulu Mentalcare Oy
  - Oulu, Finland, 90100
    - Terveystalo Oulu, Diapolis
  - Pori, Finland, 28100
    - Porin Lääkäritalo Oy
  - Siilinjarvi, Finland, 71800
    - Terveystalo Siilinjarvi
  - Tampere, Finland, 33520
    - FinnMedi Oy
  - Turku, Finland, 20520
    - Turku University Hospital
  - Turku, Finland, 20100
    - Terveystalo Pulssi
  - Vantaa, Finland, 01600
    - Vantaan Tutkimuskeskus
Forenede Stater
- Alabama
  - Athens, Alabama, Forenede Stater, 35611
    - North Alabama Research Center, LLC
  - Athens, Alabama, Forenede Stater, 35611
    - Ernest Hendrix, MD, PC
  - Birmingham, Alabama, Forenede Stater, 35211
    - Clinical Research Advantage, Inc./Simon Williamson Clinic
  - Birmingham, Alabama, Forenede Stater, 35209
    - Central Alabama Research
  - Birmingham, Alabama, Forenede Stater, 35233
    - The Kirklin Clinic
  - Birmingham, Alabama, Forenede Stater, 35235
    - Birmingham Heart Clinic, P.C.
  - Birmingham, Alabama, Forenede Stater, 35294
    - University of Alabama at Birmingham (Drug Shipment)
  - Fort Payne, Alabama, Forenede Stater, 35967
    - Appalachian Cardiovascular Associates
  - Gulf Shores, Alabama, Forenede Stater, 36542
    - Fundamental Research, LLC
  - Guntersville, Alabama, Forenede Stater, 35976
    - Avant Research Associates, LLC
  - Hamilton, Alabama, Forenede Stater, 35570
    - Boyett Health Services
  - Huntsville, Alabama, Forenede Stater, 35801
    - The Office of Saadat Ansari MD LLC
  - Mobile, Alabama, Forenede Stater, 36608
    - CB Flock Research Corporation
- Alaska
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Heart Institute
- Arizona
  - Glendale, Arizona, Forenede Stater, 85306
    - Phoenix Heart, PLLC
  - Glendale, Arizona, Forenede Stater, 85308
    - Arrowhead Internal Medicine
  - Phoenix, Arizona, Forenede Stater, 85018
    - Clinical Research Advantage, Inc./Family Practice Specialists, Ltd.
  - Sierra Vista, Arizona, Forenede Stater, 85635
    - Cochise Clinical Research
  - Tempe, Arizona, Forenede Stater, 85282
    - Clinical Research Advantage, Inc. (Administrative Mailing Only)
  - Tucson, Arizona, Forenede Stater, 85710
    - Southwest Heart Group
  - Tucson, Arizona, Forenede Stater, 85715
    - Arizona Endocrine and Rheumatology Associates
- Arkansas
  - Little Rock, Arkansas, Forenede Stater, 72211
    - Arkansas Heart Hospital Clinic
  - Little Rock, Arkansas, Forenede Stater, 72211
    - Arkansas Site Management Services, LLC
- California
  - Anaheim, California, Forenede Stater, 92801
    - Cardiology Consultants of Orange County Medical Group, Inc.
  - Bakersfield, California, Forenede Stater, 93309
    - Premier Valley Medical Group
  - Beverly Hills, California, Forenede Stater, 90211
    - Westside Medical Associates of Los Angeles
  - Beverly Hills, California, Forenede Stater, 90210
    - Cardiovascular Research Foundation of Southern California
  - Buena Park, California, Forenede Stater, 90620
    - Southbay Pharma Research
  - Cerritos, California, Forenede Stater, 90703
    - Pioneer Medical Group
  - Concord, California, Forenede Stater, 94520
    - John Muir Physician Network Clinical Research Center
  - Cudahy, California, Forenede Stater, 90201
    - Atlantic Ave Medical Clinic Inc.
  - Downey, California, Forenede Stater, 90241
    - Multani Medical Group
  - El Cajon, California, Forenede Stater, 92020
    - TriWest Research Associates, LLC
  - Encinitas, California, Forenede Stater, 92024
    - Diagnamics Inc.
  - Encino, California, Forenede Stater, 91436
    - T. Joseph Raoof, Md, Inc/Encino Research Center
  - Escondido, California, Forenede Stater, 92025
    - AVIVA Research
  - Fresno, California, Forenede Stater, 93720
    - Valley Research
  - Fullerton, California, Forenede Stater, 92835
    - St. Jude Hospital Yorba Linda dba St. Joseph Heritage Healthcare
  - La Palma, California, Forenede Stater, 90623
    - Omnibus Clinical Research
  - Laguna Hills, California, Forenede Stater, 92653
    - Alliance Research Centers
  - Laguna Hills, California, Forenede Stater, 92653
    - Prime Care Clinical Research Center
  - Lincoln, California, Forenede Stater, 95648
    - Clinical Trials Research
  - Long Beach, California, Forenede Stater, 90806
    - Long Beach Memorial Medical Center
  - Los Angeles, California, Forenede Stater, 90022
    - Academic Medical Research Institute
  - Los Angeles, California, Forenede Stater, 90017
    - American Institute of Research
  - Los Angeles, California, Forenede Stater, 90017
    - Intermed Group
  - Los Angeles, California, Forenede Stater, 90022
    - Eastside Clinical Research Associates
  - Los Gatos, California, Forenede Stater, 95032
    - Richard S. Cherlin, MD
  - Mission Hills, California, Forenede Stater, 91345
    - FACEY Medical Foundation
  - Northridge, California, Forenede Stater, 91325
    - Valley Clinical Trials, Inc.
  - Northridge, California, Forenede Stater, 91324
    - California Medical Research Associates Inc.
  - Orange, California, Forenede Stater, 92868
    - Diabetes Associates Medical Group
  - Port Hueneme, California, Forenede Stater, 93041
    - Saviers Medical Group
  - San Diego, California, Forenede Stater, 92103-6204
    - California Research Foundation
  - San Diego, California, Forenede Stater, 92111
    - San Diego Family Care dba Linda Vista Health Center
  - San Diego, California, Forenede Stater, 92111
    - San Diego Family Care
  - San Diego, California, Forenede Stater, 92117
    - Ritchken & First Md's
  - San Diego, California, Forenede Stater, 92120
    - Wetlin Research Associates, Inc.
  - San Ramon, California, Forenede Stater, 94582
    - West Coast Research LLC
  - Santa Ana, California, Forenede Stater, 92705
    - Syrentis Clinical Research
  - Santa Monica, California, Forenede Stater, 90404
    - Coastal Biomedical Research, Inc.
  - Spring Valley, California, Forenede Stater, 91978
    - Encompass Clinical Research
  - Stockton, California, Forenede Stater, 95204
    - St. Joseph's Medical Associates
  - Thousand Oaks, California, Forenede Stater, 91360
    - Westlake Medical Research
  - Torrance, California, Forenede Stater, 90502
    - Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
  - Torrance, California, Forenede Stater, 90502-2004
    - Harbor-UCLA Medical Center - Torrance
  - Valley Village, California, Forenede Stater, 91607
    - Bayview Research Group
  - Ventura, California, Forenede Stater, 93003
    - Ventura Clinical Trials
  - Ventura, California, Forenede Stater, 93003
    - Coastal Metabolic Research Centre
  - Vista, California, Forenede Stater, 92083
    - Clinical Research Advantage, Inc. / Cassidy Medical Group - Vista
  - Westminster, California, Forenede Stater, 92683
    - Allianz Research Institute
  - Whittier, California, Forenede Stater, 90603
    - American Institute of Research
  - Whittier, California, Forenede Stater, 90603
    - American Institute of Research Studies
  - Wildomar, California, Forenede Stater, 92595
    - Elite Clinical Trials, Inc.
  - Wildomar, California, Forenede Stater, 92595
    - Elite Clinical Trials, Incorporated
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Lynn Institute of the Rockies
  - Colorado Springs, Colorado, Forenede Stater, 80906
    - Colorado Springs Health Partners
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Memorial Hospital: University of Colorado Health
  - Denver, Colorado, Forenede Stater, 80246
    - Lynn Institute of Denver
  - Glenwood Springs, Colorado, Forenede Stater, 81601
    - Western Colorado Research, LLC
  - Littleton, Colorado, Forenede Stater, 80120
    - South Denver Cardiology Associates, PC
- Connecticut
  - Bridgeport, Connecticut, Forenede Stater, 06610
    - Bridgeport Hospital
  - Bridgeport, Connecticut, Forenede Stater, 06606
    - Connecticut Clinical Research, Llc
  - Stamford, Connecticut, Forenede Stater, 06905
    - Stamford Therapeutics Consortium
  - Stamford, Connecticut, Forenede Stater, 06905
    - Cardiology Associates of Fairfield County, PC
- Delaware
  - Newark, Delaware, Forenede Stater, 19713
    - Christiana Care Health Services, Inc.
  - Wilmington, Delaware, Forenede Stater, 19803
    - Alfieri Cardiology
- Florida
  - Atlantis, Florida, Forenede Stater, 33462
    - ACRC - Cardiology
  - Clearwater, Florida, Forenede Stater, 33756
    - Gulfcoast Endocrine and Diabetes Center
  - Clearwater, Florida, Forenede Stater, 33756
    - Morton Plant Mease Health Care, Inc. Cardiovascular Research
  - Coral Gables, Florida, Forenede Stater, 33134
    - Team Medical Research
  - Daytona Beach, Florida, Forenede Stater, 32117
    - Cardiology Associates Research Company
  - Daytona Beach, Florida, Forenede Stater, 32114
    - The Heart Group, PA
  - Delray Beach, Florida, Forenede Stater, 33484
    - The Cardiology Center
  - Doral, Florida, Forenede Stater, 33166
    - Integrity Clinical Research, LLC
  - Doral, Florida, Forenede Stater, 33166
    - Moonshine Research Center, Inc.
  - Doral, Florida, Forenede Stater, 33166
    - Care Research Center Inc
  - Doral, Florida, Forenede Stater, 33126
    - Continental Research Corp
  - Fort Lauderdale, Florida, Forenede Stater, 33316
    - Broward Health Medical Center
  - Fort Lauderdale, Florida, Forenede Stater, 33308
    - InvesClinic, LLC
  - Fort Lauderdale, Florida, Forenede Stater, 33316
    - The Office of Maxine E. Hamilton, MD, PA
  - Fort Lauderdale, Florida, Forenede Stater, 33308
    - The Office of Dr. Alan Graff, MD, PA
  - Hialeah, Florida, Forenede Stater, 33010
    - State Of The Art Research, LLC
  - Hialeah, Florida, Forenede Stater, 33012
    - Direct Helpers Medical Center Inc
  - Hollywood, Florida, Forenede Stater, 33021
    - Research Physicians Network Alliance
  - Hollywood, Florida, Forenede Stater, 33024
    - Pines Clinical Research, Inc.
  - Jacksonville, Florida, Forenede Stater, 32205
    - Westside Center for Clinical Research
  - Jacksonville, Florida, Forenede Stater, 32216
    - Jacksonville Center for Clinical Research
  - Jacksonville, Florida, Forenede Stater, 32216
    - East Coast Institute for Research, LLC
  - Jacksonville, Florida, Forenede Stater, 32256
    - Solutions Through Advanced Research, Inc.
  - Jacksonville, Florida, Forenede Stater, 32204
    - East Coast Institute for Research, LLC
  - Jacksonville, Florida, Forenede Stater, 32207
    - River City Clinical Research
  - Jacksonville, Florida, Forenede Stater, 32223
    - Baker-Gilmore Cardiovascular Institute
  - Jacksonville, Florida, Forenede Stater, 32216
    - East Coast Institute for Reserach, LLC
  - Jacksonville, Florida, Forenede Stater, 32216
    - The Office of Rachel Day
  - Lakeland, Florida, Forenede Stater, 33805
    - Meridien Research
  - Largo, Florida, Forenede Stater, 33770
    - The Heart Institute at Largo
  - Margate, Florida, Forenede Stater, 33063
    - South Florida Clinical Research Institute
  - Miami, Florida, Forenede Stater, 33144
    - Medical Research Center
  - Miami, Florida, Forenede Stater, 33183
    - International Research Associates, LLC
  - Miami, Florida, Forenede Stater, 33147
    - Advanced Pharma CR, LLC
  - Miami, Florida, Forenede Stater, 33126
    - Finlay Medical Research
  - Miami, Florida, Forenede Stater, 33126
    - Pharmax Research Clinic, Inc.
  - Miami, Florida, Forenede Stater, 33135
    - South Florida Research Center, Inc.
  - Miami, Florida, Forenede Stater, 33185
    - Kendall South Medical Center, Inc.
  - Miami, Florida, Forenede Stater, 33144
    - Nuren Medical & Research Center
  - Miami, Florida, Forenede Stater, 33186
    - Med Research of Florida, LLC
  - Miami, Florida, Forenede Stater, 33173
    - Research Institute of South Florida, Inc.
  - Miami, Florida, Forenede Stater, 33122
    - Future Clinical Research, Inc.
  - Miami, Florida, Forenede Stater, 33125
    - Advanced Clinical Research of Miami (ACROM) International
  - Miami, Florida, Forenede Stater, 33125
    - Project4Research, Inc
  - Miami, Florida, Forenede Stater, 33126
    - A & L Clinical research
  - Miami, Florida, Forenede Stater, 33142
    - Florida Medical Center & Research, Inc.
  - Miami, Florida, Forenede Stater, 33145
    - Doctors Research Institute
  - Miami, Florida, Forenede Stater, 33155
    - Coast Research Institute
  - Miami, Florida, Forenede Stater, 33155
    - My Community Research Center, Inc.
  - Miami, Florida, Forenede Stater, 33165
    - Columbus Clinical Services LLC
  - Miami, Florida, Forenede Stater, 33173
    - Cardiovascular Research Center of South Florida
  - Miami, Florida, Forenede Stater, 33174
    - A & O Research Center, Inc.
  - Miami, Florida, Forenede Stater, 33175
    - BWell Research Center
  - Miami, Florida, Forenede Stater, 33175
    - Pharmacology International Research, Inc.
  - Miami, Florida, Forenede Stater, 33176
    - Advanced Clinical Research
  - Miami, Florida, Forenede Stater, 33176
    - South Florida Research Group, LLC
  - Miami, Florida, Forenede Stater, 33185
    - M & M Medical Center, Inc
  - Miami, Florida, Forenede Stater, 33134
    - Team Medical Research, Inc.
  - Miami, Florida, Forenede Stater, 33134
    - Team Medical Research
  - Miami, Florida, Forenede Stater, 33185
    - Kendall South Medical Center, Inc
  - Miami Beach, Florida, Forenede Stater, 33140
    - Research Physicians Network Alliance
  - Miami Lakes, Florida, Forenede Stater, 33014
    - G & I Medical Research LLC
  - Miami Springs, Florida, Forenede Stater, 33166
    - Ocean Blue Medical Research Center, Inc.
  - Naples, Florida, Forenede Stater, 34102
    - Southwest Florida Research, LLC
  - New Port Richey, Florida, Forenede Stater, 34653
    - BayCare Medical Group
  - New Port Richey, Florida, Forenede Stater, 34653
    - The Heart & Vascular Institute Of Florida
  - North Bay Village, Florida, Forenede Stater, 33141
    - Bravo Health Care Center
  - North Miami Beach, Florida, Forenede Stater, 33162
    - Harmony Clinical Research, Inc.
  - Orlando, Florida, Forenede Stater, 32803
    - Florida Hospital
  - Orlando, Florida, Forenede Stater, 32806
    - Omega Research Consultants, LLC
  - Ormond Beach, Florida, Forenede Stater, 32174
    - Millennium Research
  - Ormond Beach, Florida, Forenede Stater, 32174
    - Aba Family Medicine, LLC
  - Ormond Beach, Florida, Forenede Stater, 32174
    - Ribo Research, LLC dba Peninsula Research
  - Pembroke Pines, Florida, Forenede Stater, 33029
    - DBC Research USA
  - Pembroke Pines, Florida, Forenede Stater, 33027
    - South Broward Research
  - Pembroke Pines, Florida, Forenede Stater, 33025
    - Research Physicians Network Alliance
  - Pembroke Pines, Florida, Forenede Stater, 33029
    - DBC Research
  - Pembroke Pines, Florida, Forenede Stater, 33024
    - A and R Research Group LLC
  - Pensacola, Florida, Forenede Stater, 32501
    - Cardiology Consultants
  - Pinellas Park, Florida, Forenede Stater, 33782
    - DMI Research, Inc.
  - Plant City, Florida, Forenede Stater, 33563
    - Clinical Research of Central Florida
  - Plant City, Florida, Forenede Stater, 33563
    - Clinical Research of Florida
  - Plantation, Florida, Forenede Stater, 33313-6066
    - Jeffrey D Greff,MD
  - Ponte Vedra, Florida, Forenede Stater, 32081
    - St. Johns Center for Clinical Research
  - Port Charlotte, Florida, Forenede Stater, 33952
    - Charlotte Heart Group Research Center
  - Saint Petersburg, Florida, Forenede Stater, 33709
    - Meridien Research
  - Saint Petersburg, Florida, Forenede Stater, 33713
    - Advance Medical Research
  - Sarasota, Florida, Forenede Stater, 34239
    - Cardiovascular Center of Sarasota
  - Sarasota, Florida, Forenede Stater, 34232
    - Intercoastal Medical Group
  - Sarasota, Florida, Forenede Stater, 34239
    - Heart & Vascular Center Research
  - Sarasota, Florida, Forenede Stater, 34239
    - Intercoastal Medical Group (Drug Shipment Address and Administrative)
  - Sarasota, Florida, Forenede Stater, 34233
    - Intercoastal Medical Group
  - Seminole, Florida, Forenede Stater, 33777
    - The Office of Bridget Bellingar, DO
  - Tamarac, Florida, Forenede Stater, 33319
    - Vita Health & Medical Center, Inc./Concept Clinical Trials, LLC
  - Trinity, Florida, Forenede Stater, 34655
    - Interventional Cardiac Consultants
  - Wellington, Florida, Forenede Stater, 33449
    - Cardiology Partners Clinical Research Institute
  - West Palm Beach, Florida, Forenede Stater, 33401
    - Metabolic Research Institute, Inc.
  - West Palm Beach, Florida, Forenede Stater, 33401
    - Cleveland Clinic Cardiology Associates
  - Winter Haven, Florida, Forenede Stater, 33880
    - Clinical Research of Central Florida
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30322
    - Emory University Hospital
  - Atlanta, Georgia, Forenede Stater, 30318
    - Atlanta Diabetes Associates
  - Atlanta, Georgia, Forenede Stater, 30331
    - Atlanta Center for Medical Research
  - Columbus, Georgia, Forenede Stater, 31904
    - Columbus Regional Research Institute
  - Conyers, Georgia, Forenede Stater, 30094
    - Rockdale Medical Research Associates
  - Covington, Georgia, Forenede Stater, 30014
    - Georgia Heart Specialists, LLC
  - Decatur, Georgia, Forenede Stater, 30033
    - NeuroStudies.net, LLC
  - Dunwoody, Georgia, Forenede Stater, 30338
    - Alta Pharmaceutical Research Center
  - Norcross, Georgia, Forenede Stater, 30071
    - In-Quest Medical Research, LLC
  - Roswell, Georgia, Forenede Stater, 30075
    - Atlanta Center for Clinical Research / Internal Medicine
  - Snellville, Georgia, Forenede Stater, 30078
    - Georgia Clinical Research, LLC
  - Snellville, Georgia, Forenede Stater, 30039
    - Dr. B. Abraham, P.C.
  - Stockbridge, Georgia, Forenede Stater, 30281
    - Clinical Research Atlanta
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96814
    - East-West Medical Research Institute
- Idaho
  - Blackfoot, Idaho, Forenede Stater, 83221
    - Elite Clinial Trials, LLLP
  - Blackfoot, Idaho, Forenede Stater, 83221
    - Elite Clinical Trials (Additional Administrative Room / Exam Rooms)
  - Caldwell, Idaho, Forenede Stater, 83605
    - St. Luke's Idaho Cardiology Associates
  - Meridian, Idaho, Forenede Stater, 83646
    - Solaris Clinical Research
  - Nampa, Idaho, Forenede Stater, 83686-6011
    - Saltzer Medical Group, PA
- Illinois
  - Arlington Heights, Illinois, Forenede Stater, 60005
    - Northwest Heart Clinical Research, LLC
  - Chicago, Illinois, Forenede Stater, 60604
    - Clinical Research Advantage, Inc./Michigan Avenue Internists
  - Chicago, Illinois, Forenede Stater, 60616
    - Apex Medical Research, AMR, Inc.
  - Chicago, Illinois, Forenede Stater, 60631
    - Clinical Research Advantage,Inc./Medical and Procedural Specilaists of Illinois
  - Evanston, Illinois, Forenede Stater, 60201
    - Evanston Premier Healthcare Research, LLC
  - Gurnee, Illinois, Forenede Stater, 60031
    - Clinical Investigation Specialists, Inc
  - Mokena, Illinois, Forenede Stater, 60448
    - Heart Care Centers of Illinois
  - Rock Island, Illinois, Forenede Stater, 61201
    - Advanced Cardiovascular Consultants
- Indiana
  - Brownsburg, Indiana, Forenede Stater, 46112
    - Investigators Research Group, Llc
  - Elwood, Indiana, Forenede Stater, 46036
    - Investigative Clinical Research of Indiana, LLC
  - Evansville, Indiana, Forenede Stater, 47714
    - MediSphere Medical Research Center, LLC
  - Evansville, Indiana, Forenede Stater, 47714
    - Clinical Research Advantage, Inc.
  - Evansville, Indiana, Forenede Stater, 47725
    - Deaconess Clinic Mt. Pleasant
  - Evansville, Indiana, Forenede Stater, 47713
    - Deaconess Clinic Downtown
  - Evansville, Indiana, Forenede Stater, 47725
    - Clinical Research Advantage, Inc. / Family Medicine Associates
  - Franklin, Indiana, Forenede Stater, 46131
    - American Health Network of Indiana LLC
  - Greenfield, Indiana, Forenede Stater, 46140
    - American Health Network of Indiana LLC
  - Muncie, Indiana, Forenede Stater, 47304
    - American Health Network of Indiana, LLC
  - Munster, Indiana, Forenede Stater, 46321
    - Cardiovascular Research of Northwest Indiana, LLC
  - Valparaiso, Indiana, Forenede Stater, 46383
    - Buynak Clinical Research, P.C.
- Iowa
  - Council Bluffs, Iowa, Forenede Stater, 51501
    - West Broadway Clinic
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Clinical Research Advantage, Inc.
  - Davenport, Iowa, Forenede Stater, 52803
    - Midwest Cardiovascular Research Foundation
  - Iowa City, Iowa, Forenede Stater, 52242
    - University of Iowa-College of Public Health-Preventive Intervention Center
  - Waterloo, Iowa, Forenede Stater, 50702
    - Northeast Iowa Medical Education Foundation
  - West Des Moines, Iowa, Forenede Stater, 50266
    - The Iowa Clinic, PC
- Kansas
  - Hutchinson, Kansas, Forenede Stater, 67502
    - Hutchinson Clinic, P.A
  - Kansas City, Kansas, Forenede Stater, 66160
    - University of Kansas Medical Center
  - Overland Park, Kansas, Forenede Stater, 66209
    - Midwest Heart & Vascular Specialists, LLC
  - Shawnee Mission, Kansas, Forenede Stater, 66218
    - Women's & Family Care, LLC D.B.A GTC Research
  - Shawnee Mission, Kansas, Forenede Stater, 66218
    - Women's & Family Care D.B.A. GTC Research
  - Shawnee Mission, Kansas, Forenede Stater, 66218
    - Women's & Family Care, LLC D.B.A. GTC Research
- Kentucky
  - Elizabethtown, Kentucky, Forenede Stater, 42701
    - Central Cardiology Associates Research
  - Lexington, Kentucky, Forenede Stater, 40503
    - The Research Group of Lexington, LLC
  - Louisville, Kentucky, Forenede Stater, 40213
    - L-MARC
  - Owensboro, Kentucky, Forenede Stater, 42303
    - Research Integrity, LLC.
- Louisiana
  - Bossier City, Louisiana, Forenede Stater, 71111
    - Grace Research, LLC
  - Crowley, Louisiana, Forenede Stater, 70526
    - Avant Research Associates, LLC
  - Lake Charles, Louisiana, Forenede Stater, 70601
    - Centex Studies
  - Lake Charles, Louisiana, Forenede Stater, 70601
    - Imperial Health, LLP
  - Marrero, Louisiana, Forenede Stater, 70072
    - American Clinical Research, LLC
  - Marrero, Louisiana, Forenede Stater, 70072
    - West Jefferson Heart Clinic of Louisiana New Orleans Physician Services, Inc.
  - Monroe, Louisiana, Forenede Stater, 71201
    - Clinical Trials of America LA
  - Natchitoches, Louisiana, Forenede Stater, 71457
    - KAMP Medical Research Inc.
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Clinical and Translation Research Center (CTRC) University Medical Center of New Orleans, Diagnostic
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Section of Nephrology and Hypertension, LSU Health Sciences Center-New Orleans
- Maine
  - Auburn, Maine, Forenede Stater, 04210
    - Maine Research Associates
  - Bangor, Maine, Forenede Stater, 04401
    - Acadia Clinical Research, LLC
  - Bangor, Maine, Forenede Stater, 04401
    - Acadia Clinical Research
  - Cape Elizabeth, Maine, Forenede Stater, 04107
    - Cranbrook Cardiology Research Associates
- Maryland
  - Annapolis, Maryland, Forenede Stater, 21401
    - Anne Arundel Medical Center
  - Annapolis, Maryland, Forenede Stater, 21401
    - Medstar Cardiology Associates
  - Baltimore, Maryland, Forenede Stater, 21229
    - Maryland Cardiovascular Specialists
  - Baltimore, Maryland, Forenede Stater, 21236
    - Overlea Personal Physicians
  - Baltimore, Maryland, Forenede Stater, 21204
    - MedStar Chesapeake CardioVascular Associates
  - Baltimore, Maryland, Forenede Stater, 21218
    - Medstar Union Memorial Heart Specialists
  - Baltimore, Maryland, Forenede Stater, 21237
    - Shahid Saeed, MD, PC
  - Glen Burnie, Maryland, Forenede Stater, 21061
    - Maryland Heart Associates, LLC
  - Lutherville, Maryland, Forenede Stater, 21093
    - Lutherville Personal Physicians
  - Oxon Hill, Maryland, Forenede Stater, 20745
    - MD Medical Research
- Massachusetts
  - Framingham, Massachusetts, Forenede Stater, 01702
    - MetroWest Medical Center
  - Framingham, Massachusetts, Forenede Stater, 01702
    - MetroWest Medical Center - Pharmacy Department
  - Framingham, Massachusetts, Forenede Stater, 01702
    - MetroWest Medical Center Research Clinic
  - Methuen, Massachusetts, Forenede Stater, 01844
    - ActivMed Practices and Research, Inc.
  - Natick, Massachusetts, Forenede Stater, 01760
    - Charles River Medical Associates
- Michigan
  - Alpena, Michigan, Forenede Stater, 49707
    - Endeavor Medical Research
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - University of Michigan - Domino Farms
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - St. Joseph Mercy Health System (Drug shipment Only)
  - Bingham Farms, Michigan, Forenede Stater, 48025
    - Quest Research Institute
  - Chelsea, Michigan, Forenede Stater, 48118
    - IHA Chelsea Family & Internal Medicine
  - Grandville, Michigan, Forenede Stater, 49418
    - Healthy Heart Cardiology
  - Kalamazoo, Michigan, Forenede Stater, 49009
    - Westside Family Medical Center, Pc
  - Lansing, Michigan, Forenede Stater, 48912
    - Sparrow Clinical Research Institute
  - Lansing, Michigan, Forenede Stater, 48912
    - Sparrow Thoracic & Cardiovascular Institute
  - Livonia, Michigan, Forenede Stater, 48154
    - Detroit Clinical Research Center, PC
  - Midland, Michigan, Forenede Stater, 48670
    - MidMichigan Medical Center Midland
  - Saginaw, Michigan, Forenede Stater, 48601
    - Michigan Cardio Vascular Institute
  - Sterling Heights, Michigan, Forenede Stater, 48310
    - Tri-County Research, Inc.
  - Traverse City, Michigan, Forenede Stater, 49684
    - Medical Research Associates, Inc.
  - Troy, Michigan, Forenede Stater, 48085
    - Oakland Medical Research Center
  - Troy, Michigan, Forenede Stater, 48098
    - Arcturus Healthcare, PLC, Troy Internal Medicine Research Division
  - Ypsilanti, Michigan, Forenede Stater, 48197
    - Michigan Heart & Vascular Institute
- Minnesota
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Mary's Medical Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - Duluth Clinic, dba Essentia Health Duluth Clinic Investigational Drug Room
  - Duluth, Minnesota, Forenede Stater, 55805
    - The Duluth Clinic, Ltd.
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Mary's Medical Center dba Essentia Health St. Mary's Medical Center
  - Edina, Minnesota, Forenede Stater, 55435
    - Radiant Research, Inc.
  - Golden Valley, Minnesota, Forenede Stater, 55422
    - Minneapolis Clinic of Neurology
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Allina Health System, dba Abbott Northwestern Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55455
    - Lillehei Clinical Research Unit, University of Minnesota
  - Saint Cloud, Minnesota, Forenede Stater, 56303
    - Centracare Heart and Vascular Center
  - Saint Paul, Minnesota, Forenede Stater, 55102
    - HealthEast St. Joseph's Hospital inpatient Pharmacy
- Mississippi
  - Olive Branch, Mississippi, Forenede Stater, 38654
    - Olive Branch Family Medical Center
  - Tupelo, Mississippi, Forenede Stater, 38801
    - Cardiology Associates Research, LLC
- Missouri
  - Columbia, Missouri, Forenede Stater, 65201
    - Missouri Cardiovascular Specialists, LLP
  - Kansas City, Missouri, Forenede Stater, 64111
    - Saint Luke's Lipid and Diabetes Research Center
  - Kansas City, Missouri, Forenede Stater, 64128-2226
    - Kansas City VA Medical Center
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Mercy Research
- Montana
  - Kalispell, Montana, Forenede Stater, 59901
    - Glacier View Research Institute, Cardiology
  - Missoula, Montana, Forenede Stater, 59808
    - Montana Medical Research Inc.
- Nebraska
  - Lincoln, Nebraska, Forenede Stater, 68506
    - Bryan Heart
  - Omaha, Nebraska, Forenede Stater, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forenede Stater, 68131
    - Creighton Diabetes Research Center
- Nevada
  - Las Vegas, Nevada, Forenede Stater, 89119
    - AB Clinical Trials
  - Las Vegas, Nevada, Forenede Stater, 89121
    - Clinical Research of South Nevada
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Clinical Research Advantage, Inc.
- New Jersey
  - Belvidere, New Jersey, Forenede Stater, 07823
    - John V. Bernard, MD dba Wellness and Research Center
  - Bridgewater, New Jersey, Forenede Stater, 08807
    - Advanced Heart Care LLC
  - Cherry Hill, New Jersey, Forenede Stater, 08034
    - Lourdes Cardiology Services
  - Elizabeth, New Jersey, Forenede Stater, 07201
    - USMA Clinical Research
  - Hammonton, New Jersey, Forenede Stater, 08037
    - Lourdes Cardiology Services
  - Linden, New Jersey, Forenede Stater, 07036
    - NJ Heart
  - Lodi, New Jersey, Forenede Stater, 07644
    - Arysmed LLC
  - Martinsville, New Jersey, Forenede Stater, 08836
    - Amici Clinical Research, LLC
  - New Brunswick, New Jersey, Forenede Stater, 08901
    - Rutgers Biomedical and Health Sciences-Robert Wood Johnson Medical School
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - The Valley Hospital
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - Cardiac & Endovascular Associates
  - Somerset, New Jersey, Forenede Stater, 08873
    - Cardio Metabolic Institute
  - Trenton, New Jersey, Forenede Stater, 08611
    - TLB Research LLC
  - Voorhees, New Jersey, Forenede Stater, 08043
    - Lourdes Cardiology Services
  - Westwood, New Jersey, Forenede Stater, 07675
    - Westwood Cardiology Associates, P.A.
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87102
    - Albuquerque Clinical Trials, Inc.
- New York
  - Albany, New York, Forenede Stater, 12206
    - Albany Medical College, Division of Community Endocrinology
  - Brooklyn, New York, Forenede Stater, 11235
    - NY Scientific
  - Brooklyn, New York, Forenede Stater, 11214
    - Sorin Medical, P.C.
  - Brooklyn, New York, Forenede Stater, 11215
    - NY total Medical Care, PC
  - Buffalo, New York, Forenede Stater, 14215
    - Buffalo Heart Group, LLP
  - Cortlandt Manor, New York, Forenede Stater, 10567
    - NYU Hudson Valley Cardiology
  - Laurelton, New York, Forenede Stater, 11413
    - Scott Research,Inc
  - Liverpool, New York, Forenede Stater, 13088
    - SJH Cardiology Associates
  - Mineola, New York, Forenede Stater, 11501
    - Long Island Heart Associates
  - New Windsor, New York, Forenede Stater, 12553
    - Mid Hudson Medical Research, PLLC
  - New York, New York, Forenede Stater, 10065
    - Weill Cornell Medical College
  - New York, New York, Forenede Stater, 10016
    - Manhattan Medical Research Practice
  - New York, New York, Forenede Stater, 10016
    - Peters Medical Research NY, LLC
  - North Massapequa, New York, Forenede Stater, 11758-1802
    - DiGiovanna Institute for Medical Education And Research
  - Poughkeepsie, New York, Forenede Stater, 12601
    - Hudson Valley Cardiovascular Practice, PC
  - Rochester, New York, Forenede Stater, 14609
    - Rochester Clinical Research, Inc.
  - Rosedale, New York, Forenede Stater, 11422
    - Institute for clinical studies
  - Saratoga Springs, New York, Forenede Stater, 12866
    - Saratoga Clinical Research, LLC
  - Utica, New York, Forenede Stater, 13501
    - Central New York Cardiology
  - Westfield, New York, Forenede Stater, 14787
    - Great Lakes Medical Research
  - Williamsville, New York, Forenede Stater, 14221
    - Buffalo Medical Group
- North Carolina
  - Charlotte, North Carolina, Forenede Stater, 28204
    - Novant Health Heart and Vascular Institute
  - Charlotte, North Carolina, Forenede Stater, 28204
    - Novant Health Clinical Research
  - Charlotte, North Carolina, Forenede Stater, 28277
    - Sensenbrenner Primary Care
  - Clayton, North Carolina, Forenede Stater, 27520
    - NC Heart and Vascular
  - Greensboro, North Carolina, Forenede Stater, 27401
    - LeBauer Cardiovascular Research Foundation
  - Hickory, North Carolina, Forenede Stater, 28601
    - Clinical Trials of America, Inc.
  - High Point, North Carolina, Forenede Stater, 27262
    - Carolina Cardiology Cornerstone
  - Lenoir, North Carolina, Forenede Stater, 28645
    - Clinical Trials of America- NC, LLC
  - Mooresville, North Carolina, Forenede Stater, 28117
    - Research Institute of the Carolinas of Piedmont Healthcare, PA
  - Morganton, North Carolina, Forenede Stater, 28655
    - Burke Primary Care
  - New Bern, North Carolina, Forenede Stater, 28562
    - Eastern Nephrology Associates
  - Rocky Mount, North Carolina, Forenede Stater, 27804
    - PMG Research of Rocky Mount, LLC
  - Rocky Mount, North Carolina, Forenede Stater, 27804
    - Boice Willis Clinic
  - Smithfield, North Carolina, Forenede Stater, 27577
    - NC Heart and Vascular Research
  - Statesville, North Carolina, Forenede Stater, 28625
    - Piedmont Healthcare/Research
  - Winston-Salem, North Carolina, Forenede Stater, 27157
    - Wake Forest University Health Sciences Institutional Review Board
- North Dakota
  - Fargo, North Dakota, Forenede Stater, 58103
    - Lillestol Research LLC
- Ohio
  - Akron, Ohio, Forenede Stater, 44311
    - Radiant Research, Inc
  - Cincinnati, Ohio, Forenede Stater, 45246
    - Sterling Research Group, Ltd.
  - Cincinnati, Ohio, Forenede Stater, 45227
    - Metabolic and Atherosclerosis Research Center
  - Cincinnati, Ohio, Forenede Stater, 45219
    - The Lindner Center for Research and Education at The Christ Hospital
  - Cleveland, Ohio, Forenede Stater, 44122
    - Rapid Medical Research, Inc.
  - Cleveland, Ohio, Forenede Stater, 44195
    - Cleveland Clinic - Taussig Cancer Institute
  - Columbus, Ohio, Forenede Stater, 43235
    - Optimed Research, LTD
  - Columbus, Ohio, Forenede Stater, 43212
    - Radiant Research, Inc.
  - Dayton, Ohio, Forenede Stater, 45419
    - PriMED Clinical Research
  - Dayton, Ohio, Forenede Stater, 45414
    - Dayton Heart Center
  - Dayton, Ohio, Forenede Stater, 45414
    - Premier Health Specialists, Inc. (dba Dayton Heart Center)
  - Delaware, Ohio, Forenede Stater, 43015
    - Delaware Research Group, LLC
  - Elyria, Ohio, Forenede Stater, 44035
    - North Ohio Heart Center
  - Elyria, Ohio, Forenede Stater, 44035
    - North Ohio Heart Center (Administrative Only)
  - Lorain, Ohio, Forenede Stater, 44053
    - North Ohio Heart Center
  - Marion, Ohio, Forenede Stater, 43302
    - SV Research LLC
  - Perrysburg, Ohio, Forenede Stater, 43551
    - Office of Daniel G. Williams, MD
  - Sandusky, Ohio, Forenede Stater, 44870
    - North Ohio Heart Center, Inc.
  - Toledo, Ohio, Forenede Stater, 43615
    - ProMedica Northwest Ohio Cardiology Consultants
  - Youngstown, Ohio, Forenede Stater, 44501
    - Mercy Health Youngstown, LLC d/b/a St. Elizabeth Youngstown Hospital
- Oklahoma
  - Norman, Oklahoma, Forenede Stater, 73072
    - Lion Research
  - Norman, Oklahoma, Forenede Stater, 73069
    - Lion Research
  - Oklahoma City, Oklahoma, Forenede Stater, 73135
    - South Oklahoma Heart Research, LLC
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Oklahoma Heart Hospital Research Foundation
  - Oklahoma City, Oklahoma, Forenede Stater, 73103
    - COR Clinical Research LLC
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Oklahoma Heart Hospital Physicians
- Oregon
  - Ashland, Oregon, Forenede Stater, 97520
    - Integrated Medical Research PC
  - Hillsboro, Oregon, Forenede Stater, 97123
    - Hillsboro Cardiology, PC
  - Portland, Oregon, Forenede Stater, 97225
    - Portland Preventive Cardiology LLC
- Pennsylvania
  - Abington, Pennsylvania, Forenede Stater, 19001
    - Abington Hosptial
  - Altoona, Pennsylvania, Forenede Stater, 16602
    - Clinical Research Associates of Central PA
  - Downingtown, Pennsylvania, Forenede Stater, 19335-2620
    - Brandywine Clinical Research
  - Doylestown, Pennsylvania, Forenede Stater, 18901
    - Doylestown Cardiology Associates - VIAA
  - Doylestown, Pennsylvania, Forenede Stater, 18901
    - Doylestown Health Cardiology, a division of Doylestown Health Physicians
  - Feasterville-Trevose, Pennsylvania, Forenede Stater, 19053
    - Amh/Feasterville Family Health Care Center
  - Jefferson Hills, Pennsylvania, Forenede Stater, 15025
    - Greater Pittsburgh Vascular
  - Lansdale, Pennsylvania, Forenede Stater, 19446
    - Green and Seidner Family Practice Associates
  - Lansdale, Pennsylvania, Forenede Stater, 19446
    - Detweiler Family Medicine and Associates, PC
  - Levittown, Pennsylvania, Forenede Stater, 19056
    - Family Medical Associates
  - Newtown, Pennsylvania, Forenede Stater, 18940
    - Mercer Bucks Cardiology
  - Philadelphia, Pennsylvania, Forenede Stater, 19146
    - Philadelphia Health Associates-Adult Medicine
  - Pittsburgh, Pennsylvania, Forenede Stater, 15236
    - Preferred Primary Care Physicians
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - Allegheny Endocrinology Associates
  - Sayre, Pennsylvania, Forenede Stater, 18840
    - Guthrie Medical Group, PC
  - Scotland, Pennsylvania, Forenede Stater, 17254
    - SFM Clinical Trials, Inc.
  - Scottdale, Pennsylvania, Forenede Stater, 15683
    - Fay-West Family Practice
  - Sellersville, Pennsylvania, Forenede Stater, 18960
    - Grand View - Lehigh Valley Health Services, Buxmont Cardiology Division
  - Smithfield, Pennsylvania, Forenede Stater, 15478
    - Montgomery Medical, Inc.
  - Uniontown, Pennsylvania, Forenede Stater, 15401
    - Preferred Primary Care Physicians
  - Wyomissing, Pennsylvania, Forenede Stater, 19610
    - Berks Cardiologists, Ltd.
- South Carolina
  - Charleston, South Carolina, Forenede Stater, 29407
    - Coastal Cardiology
  - Greenville, South Carolina, Forenede Stater, 29615
    - Upstate Pharmaceutical Research
  - Greer, South Carolina, Forenede Stater, 29651
    - Mountain View Clinical Research, Inc.
  - Murrells Inlet, South Carolina, Forenede Stater, 29576
    - The Diabetes Center, LLC
- South Dakota
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Black Hills Cardiovascular-Regional Health Research
- Tennessee
  - Clarksville, Tennessee, Forenede Stater, 37043
    - Mid-Cumberland Infectious Disease Consultants, PLC
  - Collierville, Tennessee, Forenede Stater, 38017
    - Collierville Medical Specialists
  - Germantown, Tennessee, Forenede Stater, 38138
    - Stern Cardiovascular Foundation, Inc.
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Holston Medical Group
  - Knoxville, Tennessee, Forenede Stater, 37920
    - New Orleans Center for Clinical Research
  - Knoxville, Tennessee, Forenede Stater, 37920
    - Volunteer Research Group
  - Knoxville, Tennessee, Forenede Stater, 37909
    - New Phase Research & Development
  - Knoxville, Tennessee, Forenede Stater, 37912
    - PMG Research,Inc d/b/a PMG Research of Knoxville
  - Knoxville, Tennessee, Forenede Stater, 37917
    - Cardiovascular Research of Knoxville
  - Memphis, Tennessee, Forenede Stater, 38119
    - Baptist Memorial Medical Group, Inc.
  - Memphis, Tennessee, Forenede Stater, 38119
    - The Green Clinic, PC
  - Memphis, Tennessee, Forenede Stater, 38125
    - Southwind Medical Specialists
  - Tullahoma, Tennessee, Forenede Stater, 37388
    - Tennessee Center for Clinical Trials
  - Tullahoma, Tennessee, Forenede Stater, 37388
    - Trinity Clinical Research, LLC
- Texas
  - Amarillo, Texas, Forenede Stater, 79106
    - PharmaTex Research
  - Arlington, Texas, Forenede Stater, 76012
    - Arlington Family Research Center, Inc.
  - Austin, Texas, Forenede Stater, 78731
    - Texas Diabetes & Endocrinology
  - Austin, Texas, Forenede Stater, 78756
    - Austin Heart, PLLC
  - Channelview, Texas, Forenede Stater, 77530
    - Aztec Medical Research, LLC
  - Corsicana, Texas, Forenede Stater, 75110
    - Corsicana Medical Research, PLLC
  - Dallas, Texas, Forenede Stater, 75230
    - Dallas Diabetes and Endocrine Center
  - Dallas, Texas, Forenede Stater, 75231
    - Research Institute Of Dallas
  - Dallas, Texas, Forenede Stater, 75231
    - Cardiovascular Research Institute of Dallas
  - Dallas, Texas, Forenede Stater, 75231
    - Radiant Research, Inc.
  - Dallas, Texas, Forenede Stater, 75208
    - Protenium Clinical Research, LLC
  - Dallas, Texas, Forenede Stater, 75216
    - VA North Texas Health Care System - Dallas VAMC
  - Dallas, Texas, Forenede Stater, 75226
    - Baylor Heart and Vascular Institute
  - Edinburg, Texas, Forenede Stater, 78539
    - Doctors Hospital at Renaissance
  - Fort Worth, Texas, Forenede Stater, 76164
    - Rockwood Medical Clinic
  - Fort Worth, Texas, Forenede Stater, 76104
    - Amir Malik Research
  - Fort Worth, Texas, Forenede Stater, 76104
    - The Medical Group Of Texas
  - Georgetown, Texas, Forenede Stater, 78626
    - San Gabriel Clinical Research, LLC
  - Houston, Texas, Forenede Stater, 77030
    - Baylor College of Medicine
  - Houston, Texas, Forenede Stater, 77081
    - Texas Center for Drug Development, Inc.
  - Houston, Texas, Forenede Stater, 77058
    - Centex Studies, Inc.
  - Houston, Texas, Forenede Stater, 77002
    - Spring Clinical Research
  - Houston, Texas, Forenede Stater, 77024
    - Prime Care Medical Group
  - Houston, Texas, Forenede Stater, 77002
    - East Texas Cardiology PA
  - Houston, Texas, Forenede Stater, 77024
    - Med Tech Research, LP
  - Houston, Texas, Forenede Stater, 77027
    - Associates in Medicine, PA
  - Houston, Texas, Forenede Stater, 77030
    - Alan S. Hoffman, M.D.
  - Houston, Texas, Forenede Stater, 77094
    - Private Practice Leadership, LLC
  - Houston, Texas, Forenede Stater, 77030
    - Investigational Product Shipment Address TO: Investigational Drug Services (IDS),
  - Houston, Texas, Forenede Stater, 77070
    - Northwest Houston Cardiology
  - Hurst, Texas, Forenede Stater, 76054
    - Protenium Clinical Research
  - Kerrville, Texas, Forenede Stater, 78028
    - South Texas Cardiovascular Consultants, PLLC
  - Lubbock, Texas, Forenede Stater, 79410
    - Caprock Cardiac Center Research Institute Inc.
  - Midland, Texas, Forenede Stater, 79707
    - Midland Clinical Research Center
  - New Braunfels, Texas, Forenede Stater, 78130
    - Hill Country Medical Associates
  - North Richland Hills, Texas, Forenede Stater, 76180
    - North Hills Medical Research, Inc.
  - Palestine, Texas, Forenede Stater, 75801
    - Grace Research, LLC
  - Pasadena, Texas, Forenede Stater, 77504
    - Med-Olam Clinical Research
  - Pflugerville, Texas, Forenede Stater, 78660
    - Austin Institute for Clinical Research, Inc.
  - Pflugerville, Texas, Forenede Stater, 78660
    - Austin Institute for Clinical Research,Inc.
  - Pharr, Texas, Forenede Stater, 78577
    - Centex Studies, Inc
  - Plano, Texas, Forenede Stater, 75024
    - Legacy Heart Center
  - San Antonio, Texas, Forenede Stater, 78215
    - Sun Research Institute
  - San Antonio, Texas, Forenede Stater, 78221
    - Southwest Clinic
  - San Antonio, Texas, Forenede Stater, 78201
    - South Texas Cardiovascular Consultants, PLLC
  - San Antonio, Texas, Forenede Stater, 78231
    - Victorium Clinical Research
  - San Antonio, Texas, Forenede Stater, 78249
    - Bandera Family Health Care, LLC
  - Schertz, Texas, Forenede Stater, 78154
    - Northeast Clinical Research of San Antonio, LLC (NECRSA, LLC)
  - Sugar Land, Texas, Forenede Stater, 77479
    - Sugar Lakes Family Practice
  - Sugar Land, Texas, Forenede Stater, 77478
    - IP + Dry ice deliveries Sugar Lakes Family Practice
  - Sugar Land, Texas, Forenede Stater, 77478
    - Acacia Medical Research Institute, LLC
  - Tomball, Texas, Forenede Stater, 77375-4536
    - Northwest Houston Heart Center
  - Tomball, Texas, Forenede Stater, 77375
    - Northwest Heart Center
  - Tomball, Texas, Forenede Stater, 77375
    - Admin & Storage only:Northwest Heart Center
  - Tomball, Texas, Forenede Stater, 77375
    - Northwest Houston Clinical Research, PLLC
  - Victoria, Texas, Forenede Stater, 77901
    - Victoria Heart and Vascular Center, PA
- Utah
  - Bountiful, Utah, Forenede Stater, 84010
    - Utah Cardiology, PC
  - Layton, Utah, Forenede Stater, 84041
    - Utah Cardiology, P.C.
  - Ogden, Utah, Forenede Stater, 84405
    - Paramount Medical Care
  - Orem, Utah, Forenede Stater, 84058
    - Aspen Clinical Research LLC
  - Provo, Utah, Forenede Stater, 84604
    - Revere Health
  - Salt Lake City, Utah, Forenede Stater, 84102
    - Optimum Clinical Research, Inc.
  - Salt Lake City, Utah, Forenede Stater, 84117
    - Holladay Family Practice
  - Salt Lake City, Utah, Forenede Stater, 84107
    - Wasatch Clinical Research, LLC
  - Salt Lake City, Utah, Forenede Stater, 84124
    - Heart Center at St. Mark's Hospital
- Virginia
  - Burke, Virginia, Forenede Stater, 22015
    - Burke Internal Medicine & Research
  - Burke, Virginia, Forenede Stater, 22015
    - Clinical Research Institute of Northern Virginia
  - Falls Church, Virginia, Forenede Stater, 22042
    - Virginia Heart
  - Falls Church, Virginia, Forenede Stater, 22044
    - Seven Corners Medical Research Center
  - Hopewell, Virginia, Forenede Stater, 23860
    - Heart Care Associates, P.C.
  - Midlothian, Virginia, Forenede Stater, 23114
    - Virginia Research Center
  - Richmond, Virginia, Forenede Stater, 23225
    - Chippenham and Johnston Willis Hospitals, Inc. dba CJW Medical Center
  - Richmond, Virginia, Forenede Stater, 23225
    - Retreat Cardiology LLC, dba Cardiology Associates of Richmond
  - Roanoke, Virginia, Forenede Stater, 24014
    - Roanoke Heart Institute
  - Suffolk, Virginia, Forenede Stater, 23435
    - Hampton Roads Center for Clinical Research
- Washington
  - Burien, Washington, Forenede Stater, 98166
    - Office of Daniel W. Gottlieb, MD, PS
  - Spokane, Washington, Forenede Stater, 99202
    - Premier Clinical Research
  - Tacoma, Washington, Forenede Stater, 98405
    - Universal Research Group, LLC
  - Walla Walla, Washington, Forenede Stater, 99362
    - Walla Walla Clinic
  - Wenatchee, Washington, Forenede Stater, 98801
    - Wenatchee Valley Hospital & Clinics
- West Virginia
  - Fairmont, West Virginia, Forenede Stater, 26554
    - Exemplar Research Inc
- Wisconsin
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - Prevea Clinic, Inc.
  - Kenosha, Wisconsin, Forenede Stater, 53142
    - Clinical Investigation Specialists, Inc.
  - Waukesha, Wisconsin, Forenede Stater, 53188
    - Waukesha Heart Foundation
Frankrig
- - Besancon, Frankrig, 25000
    - CHU Jean Minjoz Cardiologie
  - Bourg En Bresse Cedex 10000, Frankrig, 01012
    - Centre Hospitalier De Bourg En Bresse - Hopital Fleyriat
  - Caen cedex 9, Frankrig, 14033
    - CHU de Caen
  - Cannes Cedex, Frankrig, 06414
    - Centre Hospitalier de Cannes- Service de Cardiologie
  - Corbeil-Essonnes, Frankrig, 91106
    - Centre Hospitalier Sud-Francilien
  - Essey-Les-Nancy, Frankrig, 54270
    - Scp Cardiovasculaire De L'Est
  - Le Coudray, Frankrig, 28630
    - Centre Hospitalier Louis Pasteur
  - Lille, Frankrig, 59000
    - Hôpital La Louvière
  - Lomme, Frankrig, 59462
    - Centre Hospitalier Saint Philibert
  - Lyon Cedex 03, Frankrig, 69394
    - Hopital Cardiovasculaire et Pneumologique Louis Pradel
  - Montpellier cedex 5, Frankrig, 34295
    - Hopital Arnaud de Villeneuve
  - Nantes, Frankrig, 44093
    - CHU de Nantes - Hopital Nord Laennec
  - Nantes, Frankrig, 44200
    - Nouvelles Cliniques Nantaises
  - Nimes, Frankrig, 30000
    - CHU Caremeau
  - Nimes cedex 9, Frankrig, 30029
    - CHU Caremeau
  - PAU, Frankrig, 64046
    - Centre Hospitalier de Pau
  - Pessac cedex, Frankrig, 33604
    - Hôpital Cardiologique
  - Poitiers cedex, Frankrig, 86021
    - CHU De Poitiers
  - Rennes Cedex 9, Frankrig, 35033
    - CHU de Renes Hopital de Pontchaillou
  - Toulouse cedex 9, Frankrig, 31059
    - CHU de Toulouse
  - Tourcoing, Frankrig, 59200
    - Hopital Guy Chatiliez
  - Tours Cedex 9, Frankrig, 37044
    - Hôpital Trousseau
  - Valenciennes, Frankrig, 59300
    - Polyclinique Vauban
  - Valenciennes, Frankrig, 59300
    - Centre Hospitalier (CH) de Valenciennes
Holland
- - Alkmaar, Holland, 1815 JD
    - Noordwest Ziekenhuisgroep
  - Almere, Holland, 1311 RL
    - EB FlevoResearch
  - Amersfoort, Holland, 3813 TZ
    - Meander Medisch Centrum
  - Amersfoort, Holland, 3813 TZ
    - Meander Medical Center
  - Amstelveen, Holland, 1186 AM
    - Amstelland Hospital
  - Amsterdam, Holland, 1105 AZ
    - Academic Medical Center
  - Amsterdam, Holland, 1081 HV
    - VU University Medical Center
  - Amsterdam, Holland, 1091 AC
    - Onze Lieve Vrouwe Gasthuis
  - Amsterdam, Holland, 1034 CS
    - BovenIJ ziekenhuis
  - Amsterdam, Holland, 1061 AE
    - OLVG, locatie West
  - Apeldoorn, Holland, 7334 DZ
    - Gelre Hospitals
  - Beverwijk, Holland, 1942 LE
    - Rode Kruis Ziekenhuis
  - Blaricum, Holland, 1261 AN
    - Tergooi Ziekenhuis
  - Breda, Holland, 4818 CK
    - Amphia Ziekenhuis
  - Breda, Holland, 4811 SW
    - Andro Medical Research B.V.
  - Delft, Holland, 2625 AD
    - Reinier de Graaf Ziekenhuis
  - Den Haag, Holland, 2545 CH
    - Hagaziekenhuis
  - Den Haag, Holland, 2526 HW
    - Hedramed
  - Den Haag, Holland, 2597 AX
    - Bronovo Ziekenhuis
  - Deventer, Holland, 7416SE
    - Deventer Ziekenhuis
  - Dirksland, Holland, 3247 BW
    - Van Weel Bethesda Hospital
  - Doetinchem, Holland, 7009 BL
    - Slingeland Ziekenhuis
  - Dordrecht, Holland, 3318 AT
    - Albert Schweitzer Ziekenhuis-Albert Schweitzer Hospital
  - Ede, Holland, 6716 RP
    - Ziekenhuis Gelderse Vallei
  - Eindhoven, Holland, 5611 NV
    - Andromed Eindhoven
  - Eindhoven, Holland, 5623 EJ
    - Heartcentre Catharina Hospital
  - Enschede, Holland, 7512 KZ
    - Medisch Spectrum Twente
  - Gorinchem, Holland, 4204 AA
    - Beatrix Ziekenhuis
  - Gorinchem, Holland, 4204 AA
    - Beatrix Hospital
  - Gouda, Holland, 2803 HH
    - Groene Hart Ziekenhuis
  - Groningen, Holland, 9713 GZ
    - University Medical Center Groningen
  - Groningen, Holland, 9728 NT
    - Martini Ziekenhuis
  - Haarlem, Holland, 2035 RC
    - Spaarne Gasthuis
  - Hardenberg, Holland, 7772 SE
    - Ropcke Zweers Hospital
  - Harderwijk, Holland, 3844 DG
    - St. Jansdal Ziekenhuis
  - Heerlen, Holland, 6419 PC
    - Zuyderland Medisch Centrum
  - Heerlen, Holland, 6419PC
    - Zuyderland
  - Hoogeveen, Holland, 7909 AA
    - Treant Zorggroep, location Bethesda
  - Hoorn, Holland, 1624 NP
    - Vascular Research Centre
  - Kloosterhaar, Holland, 7694 AC
    - Quality Care Research
  - Leeuwarden, Holland, 8934 AD
    - Medisch Centrum Leeuwarden
  - Leiden, Holland, 2333 ZA
    - Leiden University Medical Center
  - Leiden, Holland, 2334 CK
    - Alrijne Ziekenhuis
  - Leiderdorp, Holland, 2353 GA
    - Alrijne Ziekenhuis
  - Maarssen, Holland, 3607 KN
    - GCM Maarssenbroek
  - Maastricht, Holland, 6229 HX
    - Maastricht University Medical Center
  - Meppel, Holland, 7943 KA
    - Isala Diaconessenhuis
  - Nieuwegein, Holland, 3435 CM
    - St Antonius Hospital
  - Nijmegen, Holland, 6532 SZ
    - Canisius Wilhelmina Ziekenhuis
  - Nijmegen, Holland, 6525 GA
    - Radboud University Nijmegen Medical Centre
  - Purmerend, Holland, 1441 RN
    - Waterland Hospital
  - Rotterdam, Holland, 3039 BD
    - Rotterdam Research Institute
  - Rotterdam, Holland, 3021 HC
    - Andro Medical Research B.V.
  - Rotterdam, Holland, 3037 AN
    - Hedramed
  - Rotterdam, Holland, 3083AN
    - Ikazia Ziekenhuis
  - Sneek, Holland, 8601 ZR
    - D&A Research and Genetics
  - Tiel, Holland, 4002 WP
    - Ziekenhuis Rivierenland
  - Tilburg, Holland, 5022 GC
    - St. Elisabeth Ziekenhuis
  - Tilburg, Holland, 5022 GC
    - Elisabeth-TweeSteden Ziekenhuis (previously named St. Elisabeth Ziekenhuis)
  - Tilburg, Holland, 5042 AD
    - Elisabeth TweeSteden Ziekenhuis (ETZ)
  - Uden, Holland, 5406 PT
    - Bernhoven Ziekenhuis
  - Utrecht, Holland, 3584 CX
    - University Medical Center Utrecht
  - Utrecht, Holland, 3511 NH
    - EB Utrecht
  - Utrecht, Holland, 3584 CX
    - Universitair Medisch Centrum (UMC) Utrecht - Locatie AZU
  - Veldhoven, Holland, 5504 DB
    - Maxima Medisch Centrum
  - Venlo, Holland, 5912 BL
    - VieCuri Medisch Centrum
  - Waalwijk, Holland, 5141 BM
    - Twee Steden Ziekenhuis
  - Zoetermeer, Holland, 2712 AB
    - Klinisch Onderzoek Praktijk Zoetermeer
  - Zwijndrecht, Holland, 3331 LZ
    - Albert Schweitzer Hospital
- Friesland
  - Heerenveen, Friesland, Holland, 8441 PW
    - Tjongerschans Ziekenhuis
- Limburg
  - Sittard-Geleen, Limburg, Holland, 6162 BG
    - Zuyderland MC
- Overijssel
  - Zwolle, Overijssel, Holland, 8025 AB
    - Isala
- Zuid-holland
  - Rotterdam, Zuid-holland, Holland, 3045 PM
    - St. Franciscus Gasthuis
  - Zoetermeer, Zuid-holland, Holland, 2725 NA
    - Het Lange Land Ziekenhuis
Indien
- Gujarat
  - Ahmedabad, Gujarat, Indien, 380007
    - Dr. Jivraj Mehta Smarak Health Foundation, Bakeri Medical Research Centre
  - Ahmedabad, Gujarat, Indien, 380054
    - Apex Heart Institute (A Unit of TCVS Pvt. Ltd)
  - Ahmedabad, Gujarat, Indien, 380054
    - SAL Hospital
  - Surat, Gujarat, Indien, 395 002
    - Apple Hospital
  - Surat, Gujarat, Indien, 395002
    - Unicare Heart Institute & Research Center
  - Surat, Gujarat, Indien, 395009
    - BAPS - Pramukh Swami Hospital
  - Vadodara, Gujarat, Indien, 390022
    - Rhythm Heart Institute
- Maharashtra
  - Pune, Maharashtra, Indien, 411001
    - Jehangir Clinical Development Centre Pvt. Ltd.
- Uttar Pradesh
  - Lucknow, Uttar Pradesh, Indien, 226003
    - M.V. Hospital and Research Centre
Irland
- - Dublin, Irland, 8
    - St James's Hospital
- Leinster
  - Dublin, Leinster, Irland, 9
    - Beaumont Hospital
Israel
- - Ashkelon, Israel, 7830604
    - Barzilai Medical Center
  - Beer Sheva, Israel, 84350
    - Ben Yair Community Clinic - Clalit Health Services
  - Hadera, Israel, 38100
    - Heart Institute, Hillel Yaffe Medical Center
  - Haifa, Israel, 31096
    - Rambam Medical Center
  - Haifa, Israel, 34362
    - Cardiovascular Clinical Research Institute
  - Holon, Israel, 58100
    - Edith Wolfson Medical Center
  - Jerusalem, Israel, 91120
    - Hadassah Ein Kerem Medical Center
  - Kfar Sava, Israel, 44281
    - Meir Medical Center
  - Kfar-Saba, Israel, 44281
    - Meir Medical Center
  - Nahariya, Israel, 22100
    - Galilee Medical Center, Cardiology Department
  - Nazareth, Israel, 16100
    - E.M.M.S Nazareth Hospital
  - Petach Tikva, Israel, 4958202
    - Sha'aria Clinic, Clalit Health Services
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center, Beilinson Hospital
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center-Beilinson Hospital
  - Raanana, Israel, 43452
    - Shuali Community Clinic, Clalit Health Services
  - Ramat Gan, Israel, 52621
    - Department of Neurology & Sagol Neuroscience Center
  - Rehovot, Israel, 76100
    - Heart Institute, Kaplan Medical Center
  - Rehovot, Israel, 76100
    - Kaplan Medical Center Metabolism and Diabetes Clinic, Kaplan Medical Center
  - Safed, Israel, 13100
    - Ziv Medical Center
  - Safed, Israel, 13100
    - Internal Medicine A, Ziv Medical Center
  - Tel Aviv, Israel, 6789140
    - Assuta Medical Center
  - Tel Hashomer, Israel, 5265601
    - The Chaim Sheba Medical Center
  - Tel-Aviv, Israel, 64239
    - Tel Aviv Sourasky Medical Center
- Tel-aviv
  - Tel Aviv, Tel-aviv, Israel, 64239
    - Tel Aviv Sourasky Medical Center
Italien
- - Ancona, Italien, 60124
    - S. C. Cardiologia INRCA
  - Belluno, Italien, 32100
    - Ospedale Civile Regionale San Martino, Belluno
  - Cagliari, Italien, 09124
    - Azienda Ospedaliera G. Brotzu
  - Milan, Italien, 20138
    - Unità Operativa Solventi e Unità Poliambulatorio
  - Napoli, Italien, 80131
    - Department of Clinical Medicines and Cardiovascular Sciences, Universita "Federico II" di Napoli
  - Napoli, Italien, 80131
    - Divisione di Cardiologia con Utic ed Emodinamica - AOU Federico II di Napoli
  - Reggio Emilia, Italien, 42123
    - A.O. di Reggio Emilia Arcispedale "S. Maria Nuova"/IRCCS
  - Rimini, Italien, 47923
    - AUSL Della Romagna-Ospedale Infermi
  - Rovigo, Italien, 45100
    - Ospedale Santa Maria della Misericordia Azienda ULSS 18 of Rovigo
  - Udine, Italien, 33100
    - Azienda Ospedaliera Universitaria Santa Maria della Misericordia
- Bergamo
  - Treviglio (BG), Bergamo, Italien, 24047
    - A.O. Treviglio e Caravaggio
- CZ
  - Catanzaro, CZ, Italien, 88100
    - AOU Policlinico "Mater Domini" UOC di Medicina Interna
- Geneve
  - Meyrin/Geneve, Geneve, Italien, 1217
    - Covance Central Laboratory Services
- Lecco
  - Merate, Lecco, Italien, 23807
    - Ospedale S. L. Mandic di Merate
- PA
  - Palermo, PA, Italien, 90127
    - Dipartimento delle Patologie Emergenti, Unita di Medicina Interna e Dislipidemie Genetiche
- PG
  - Perugia, PG, Italien, 06132
    - Ospedale S. Maria della Misericordia -Dipartimento di Medicina, Medicina Interna,
- Province OF Lecco
  - Lecco, Province OF Lecco, Italien, 23900
    - Azienda Ospedaliera Della Provincia Di Lecco - Ospedale Manzoni
- RM
  - Roma, RM, Italien, 00161
    - Dip Medicina Interna e Specialita Mediche, Policlinico Umberto I
  - Rome, RM, Italien, 00161
    - Policlinico Umberto i di Roma
  - Rome, RM, Italien, 00189
    - Azienda Ospedaliera S'Andrea di Roma - UOC Cardiologia
- VR
  - Verona, VR, Italien, 37126
    - AOUI di Verona - Ospedale Civile Maggiore Borgo Trento
- Verona
  - San Bonifacio, Verona, Italien, 37047
    - Ospedale G. Fracastoro
Kalkun
- - Adana, Kalkun, 01250
    - Baskent University, Adana Yuregir Training & Research Hospital
  - Afyonkarahisar, Kalkun, 03200
    - A.karahisar Kocatepe Universitesi Hastanesi Ahmet Needet Sezer Uygulama ve
  - Ankara, Kalkun, 06110
    - Diskapi Yildirim Beyazit Egitim ve Arastirma Hastanesi
  - Ankara, Kalkun, 06520
    - Ufuk University School of Medicine, Dr. Ridvan Ege Training & Research Hospital
  - Antalya, Kalkun, 07059
    - Akdeniz Universitesi Tip Fakultesi
  - Antalya, Kalkun, 07100
    - Antalya Training & Research Hospital
  - Aydin, Kalkun, 09100
    - Adnan Menderes Universitesi Uygulama ve Arastirma Hastanesi
  - Bursa, Kalkun, 16320
    - Bursa Yuksek Ihtisas Egitim ve Arastirma Hastanesi
  - Elazig, Kalkun, 23119
    - FIRAT ÜNİVERSİTESİ
  - Gaziantep, Kalkun, 27310
    - Gaziantep Universitesi Tip Fakultesi Sahinbey Egitim ve Arastirma Hastanesi
  - Istanbul, Kalkun, 34093
    - Istanbul Universitesi Istanbul Tip Fakultesi
  - Istanbul, Kalkun, 34096
    - Istanbul Universitesi Kardiyoloji Enstitusu
  - Istanbul, Kalkun, 34093
    - Bezmialem Vakif Universitesi Tip Fakultesi Kardiyoloji Bolurnu
  - Izmir, Kalkun, 35340
    - Dokuz Eylul Universitesi Tip Fakultesi
  - Izmir, Kalkun, 35100
    - Ege University, School of Medicine
  - Izmir, Kalkun, 35170
    - Izmir Tepecik Egitim ve Arastirma Hastanesi
  - Izmir, Kalkun, 35340
    - Dokuz Eylul Universitesi Tip Fakültesi Hastanesi
  - Kocaeli, Kalkun, 41380
    - Kocaeli University School Of Medicine-Kocaeli Universitesi Tip Fakultesi
  - Mersin, Kalkun, 33343
    - Mersin University, School of Medicine
  - Rize, Kalkun, 53020
    - Recep Tayyip Erdogan University School of Medicine, Training & Research Hospital
Korea, Republikken
- - Busan, Korea, Republikken, 49201
    - Dong-A University Hospital
  - Busan, Korea, Republikken, 47392
    - Inje University Busan Paik Hospital
  - Daegu, Korea, Republikken, 42472
    - Daegu Catholic University Medical Center
  - Incheon, Korea, Republikken, 21565
    - Gachon University Gil Medical Center
  - Seoul, Korea, Republikken, 05505
    - Asan Medical Center
  - Seoul, Korea, Republikken, 134-701
    - Hallym University Kangdong Sacred Heart Hospital
  - Seoul, Korea, Republikken, 131-795
    - Seoul Medical Center
  - Seoul, Korea, Republikken, 135-720
    - Gangnam Severance Hospital, Yonsei University Health System
  - Seoul, Korea, Republikken, 137-701
    - The Catholic University Of Korea Seoul St.Marys Hospital
  - Seoul, Korea, Republikken, 156-707
    - Seoul Metropolitan Government - Seoul National University Boramae Medical Center
- Chungcheonbuk-do
  - Cheongju-si, Chungcheonbuk-do, Korea, Republikken, 362-711
    - Chungbuk National University Hospital
- Gangwon-do
  - Chuncheon-si, Gangwon-do, Korea, Republikken, 24289
    - Kangwon National University Hospital
  - Wonju-Si, Gangwon-do, Korea, Republikken, 26426
    - Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital
  - Wonju-si, Gangwon-do, Korea, Republikken, 26426
    - Yonsei University Wonju Severance Christian Hospital
- Gyeongbuk
  - Gyeongju-si, Gyeongbuk, Korea, Republikken, 780-350
    - Donguk University Gyeongju Hospital
- Gyeonggi-do
  - Goyang-Si, Gyeonggi-do, Korea, Republikken, 10380
    - Inje University Ilsan Paik Hospital
  - Goyang-si, Gyeonggi-do, Korea, Republikken, 10326
    - Dongguk University Ilsan Hospital
  - Goyang-si, Gyeonggi-do, Korea, Republikken, 10475
    - Myongji Hospital
  - Seongnam-si, Gyeonggi-do, Korea, Republikken, 13620
    - Seoul National University Bundang Hospital
  - Suwon-si, Gyeonggi-do, Korea, Republikken, 443-380
    - Ajou University Hospital
  - Uijeongbu-si, Gyeonggi-do, Korea, Republikken, 11765
    - Uijeongbu St. Mary's Hospital-The Catholic University of Korea
Mexico
- - Aguascalientes, Mexico, 20230
    - Hospital Cardiologica Aguascalientes
  - Aguascalientes, Mexico, 20127
    - Instituto Biomedico De Investigacion A.C.
  - Chihuahua, Mexico, 31217
    - Investigacion en Salud y Metabolismo S.C
  - Chihuahua, Mexico, 31203
    - Unidad de Investigacion en Salud de Chihuahua S.C.
  - Chihuahua, Mexico, 31217
    - Consultorio Medico de Especialidad Dr. Demetrio Kosturakis Garcia
  - Distrito Federal, Mexico, 14000
    - Instituto Nacional de Ciencia Medicas y Nutricion Salvador Zubiran
  - Durango, Mexico, 34000
    - Lahoja Asociación para la Investigación y Farmacovigilancia S.C.
  - Mexico, Mexico, 11650
    - Centro Especializado en Diabetes, Obesidad y Prevención de Enfermedades Cardiovasculares, S.C.
  - Queretaro, Mexico, 76000
    - Pharmacology and Clinical Research S.A. de C.V.
  - San Luis Potosi, Mexico, 78200
    - Cardioarritmias e Investigación S.C.
  - San Luis Potosi, Mexico, 78218
    - Hospital Lomas de San Luis lntemacional (Emergencies)
  - San Luis Potosi, Mexico, 78240
    - Hospital Central "Dr. Ignacio Morones Prieto"
  - Veracruz, Mexico, 91910
    - Centro Especializado En Diabetes Y Metabolismo
- Chihuahua
  - Cd. Juarez, Chihuahua, Mexico, 32472
    - Consultorio Dr. Leocadio Gerardo Munoz Beltran
- DF
  - Mexico, DF, Mexico, 11650
    - Centro Especializado en Diabetes Obesidad y Prevencion de Enfermedades Cardiovasculares, SC.
- Distrito Federal
  - Mexico, Distrito Federal, Mexico, 07760
    - Consultorio de Endocrinologia y Nutriologia
  - Mexico, Distrito Federal, Mexico, 14000
    - Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán"
  - Mexico, Distrito Federal, Mexico, 07760
    - Operadora de Hospitales Angeles S.A. de C.V. (Emergencies)
- Guerrero
  - Acapulco, Guerrero, Mexico, 39670
    - Hospital Del Pacifico,Centro De Investigacion Clinica Del Pacifico Cicpa,Torre Medica Del Pacifico
  - Acapulco de Juarez, Guerrero, Mexico, 39670
    - Centro de Investigacion Clinica del Pacifico, S.A. de C.V.
- Hidalgo
  - Pachuca, Hidalgo, Mexico, 42090
    - Investigacion Biomedica Aplicada de Hidalgo S.A. de C.V.
  - Pachuca de Soto, Hidalgo, Mexico, 42070
    - Clinical Trials Mexico, S.A. de C.V.
- Jalisco
  - Guadalajara, Jalisco, Mexico, 44160
    - Centro de Investigación Médica Integral S.C.
  - Guadalajara, Jalisco, Mexico, 44657
    - Consultorio Privado del Dr. Gabriel Arturo Ramos Lopez
  - Guadalajara, Jalisco, Mexico, 44600
    - Icle S.C.
  - Guadalajara, Jalisco, Mexico, 44760
    - Unidad de Investigación Clínica y Atención Médica HEPA S.C.
- Morelos
  - Cuernavaca, Morelos, Mexico, 62250
    - Instituto de Diabetes Obesidad y Nutricion, S.C.
  - Cuernavaca, Morelos, Mexico, 62270
    - Hospital Inovamed Cuernavaca (Emergencies)
- Nuevo LEON
  - Monterrey, Nuevo LEON, Mexico, 64460
    - Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
  - Monterrey, Nuevo LEON, Mexico, 64718
    - Global Trial Research Center S.A. de C.V.
  - Monterrey, Nuevo LEON, Mexico, 64060
    - Cardiolink Clin Trials, S.C.
  - Monterrey, Nuevo LEON, Mexico, 64710
    - CRI Centro Regiomontano de Investigacion SC
- Queretaro
  - San Juan del Rio, Queretaro, Mexico, 76800
    - Centro Integral Medico SJR S.C
- Sinaloa
  - Culiacan, Sinaloa, Mexico, 80020
    - Centro para el Desarrollo de la Medicina y de Asistencia Médica Especializada S.C.
  - Culiacan, Sinaloa, Mexico, 80020
    - Hospital Angeles Culiacan
- Tamaulipas
  - Tampico, Tamaulipas, Mexico, 89000
    - Centro de Estudios de Investigacion Metabolicos y Cardiovasculares S.C.
- Veracruz
  - Xalapa, Veracruz, Mexico, 91020
    - Centro De Especialidades Medicas Del Estado De Veracruz
New Zealand
- - Auckland, New Zealand, 1023
    - Auckland City Hospital
  - Auckland, New Zealand, 1010
    - Optimal Clinical Trials
  - Auckland, New Zealand, 2025
    - Middlemore Clinical Trials
  - Auckland, New Zealand, 0622
    - North Shore Hospital, Laboratory
  - Auckland, New Zealand, 0622
    - North Shore Hospital- Inpatient Pharmacy
  - Christchurch, New Zealand, 8011
    - Lipid and Diabetes Research Group
  - Christchurch, New Zealand, 8041
    - Southern Clinical Trials Riccarton
  - Christchurch, New Zealand, 8011
    - Southern Clinical Trials Shirley Ltd Don Beavan Medical Research Centre
  - New Plymouth, New Zealand, 4310
    - Taranaki Base Hospital
  - Papamoa, New Zealand, 3118
    - Papamoa Pines Medical Centre
  - Rotorua, New Zealand, 3010
    - Rotorua Hospital
  - Tauranga, New Zealand, 3112
    - Clinical Horizons NZ Ltd
  - Tauranga, New Zealand, 3112
    - Clinical Trials Unit,Bay of Plenty(BOP) Clinical School
  - Wellington, New Zealand, 6021
    - Wellington Hospital
  - Wellington, New Zealand, 6021
    - CCDHB, Wellington Hospital, Clinical Measurement Unit
  - Wellington, New Zealand, 6242
    - Wellington Regional Hospital
- Auckland
  - Henderson, Auckland, New Zealand, 0612
    - Henderson Medical Centre
  - Takapuna, Auckland, New Zealand, 0622
    - North Shore Hospital
- Hastings
  - Frimley, Hastings, New Zealand, 4120
    - Hawke's Bay Hospital
Polen
- - Bialystok, Polen, 15-351
    - "OSTEO-MEDIC" s.c. Artur Racewicz, Jerzy Supronik
  - Bydgoszcz, Polen, 85-079
    - NZOZ Vitamed -Ga¿aj I Cichomski sp.j
  - Gdynia, Polen, 81-338
    - Medica Pro Familia Sp. z o.o. Spolka Komandytowo Akcyjna, Oddzial w Gdyni
  - Krakow, Polen, 30-053
    - Nzoz Gall-Med
  - Krakow, Polen, 31-567
    - NZOZ Centrum Zdrowia i Profilaktyki Dabie Sp. z.o.o.
  - Krakow, Polen, 31-501
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie,
  - Krakow, Polen, 31-501
    - SP ZOZ Szpital Uniwersytecki w Krakowie
  - Lodz, Polen, 90-368
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego
  - Lublin, Polen, 20-857
    - "TWOJA PRZYCHODNIA" Sp. Z o.o
  - Myslenice, Polen, 32-400
    - NeuroCor Banaszkiewicz, Kulaga, Ostrowska, Tomaszewski lekarze spolka partnerska
  - Opole, Polen, 45-706
    - Medicus w Opolu Sp z o. o.
  - Ostroda, Polen, 14-100
    - Specjalistyczny Osrodek Leczniczo-Badawczy Zbigniew Zegota
  - Oswiecim, Polen, 32-600
    - Medicome Sp. Z O.O.
  - Poznan, Polen, 60-592
    - Centrum Zdrowia Metabolicznego Pawel Bogdanski
  - Ruda Slaska, Polen, 41-709
    - NZOZ Przychodnia Specjalistyczna Andrzej wittek Henryk Rudzki S.C.
  - Staszow, Polen, 28-200
    - KO-MED Centra Kliniczne Staszow
  - Warszawa, Polen, 01-192
    - Synexus Polska Sp. z o.o. Oddzial w Warszawie
  - Warszawa, Polen, 02-637
    - Instytut Kardiologii, Ii Klinika Choroby WieCowej
  - Warszawa, Polen, 04-628
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego
  - Warszawa, Polen, 04-628
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala
  - Wroclaw, Polen, 53-301
    - Dobrostan Michal Bogacki
- Dolnoslaskie
  - Jelenia Gora, Dolnoslaskie, Polen, 58-506
    - Jeleniogorskie Centrum Chorob Serca, Przychodnia Kardiologiczna, Poradnia Kardiologiczna
  - Wroclaw, Dolnoslaskie, Polen, 51-314
    - Zdrowie S.C. Agnieszka I Donald Drozdz
  - Wroclaw, Dolnoslaskie, Polen, 50-088
    - Synexus Polska Sp. z o.o. Oddzial we Wroclawiu
  - Wroclaw, Dolnoslaskie, Polen, 51-124
    - Wojewodzki Szpital Specjalistyczny we Wroclawiu, Osrodek Badawczo-Rozwojowy
  - Zarow, Dolnoslaskie, Polen, 58-130
    - Halina Serafin NZOZ Centrum Medyczne SERAFIN-MED
- Iodzkie
  - Lodz, Iodzkie, Polen, 92-213
    - SPZOZ Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej Uniwersytetu Medycznego
- Kujawsko-pomorskie
  - Bydgoszcz, Kujawsko-pomorskie, Polen, 85-079
    - NZOZ Vitamed
  - Bydgoszcz, Kujawsko-pomorskie, Polen, 85-231
    - NZOZ Centrum Medyczne KERmed
  - Grudziadz, Kujawsko-pomorskie, Polen, 86-300
    - Specjalistyczna Praktyka Lekarska Piotr Kubalski
  - Wloclawek, Kujawsko-pomorskie, Polen, 87-800
    - Specjalistyczne Gabinety Lekarskie "Medicor Plus" - Jerzy Kopaczewski
- Lodzkie
  - Lodz, Lodzkie, Polen, 90-132
    - Gabinet Lekarski Malgorzata Saryusz-Wolska
  - Lodz, Lodzkie, Polen, 91-490
    - "Prywatny Gabinet Kardiologiczny" Dr N.Med. Maciej Kosmider
  - Lodz, Lodzkie, Polen, 90-368
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego sp. z o.o.
  - Piotrkow Trybunalski, Lodzkie, Polen, 97-300
    - Prywatny Gabinet Lekarski Dr n. med. Michal Ogorek
  - Skierniewice, Lodzkie, Polen, 96-100
    - Centrum Medyczne Ogrodowa Sp. z o.o.
- Lubelskie
  - Lublin, Lubelskie, Polen, 20-045
    - Clinical Best Solutions
  - Lublin, Lubelskie, Polen, 20-091
    - Optimamed Specjalistyczne Gabinety Lekarskie
  - Lublin, Lubelskie, Polen, 20-362
    - KO-MED Centra Kliniczne Lublin II
  - Pulawy, Lubelskie, Polen, 24-100
    - KO-MED Centra Kliniczne Pulawy
  - Zamosc, Lubelskie, Polen, 22-400
    - KO-MED Centra Kliniczne Zamosc
- Malopolskie
  - Krakow, Malopolskie, Polen, 30-015
    - LANDA Specjalistyczne Gabinety Lekarskie
  - Krakow, Malopolskie, Polen, 31-121
    - Szpital Specjalistyczny im. J. Dietla w Krakowie, Oddzial Kardiologii
  - Krakow, Malopolskie, Polen, 31-216
    - Centrum Medyczne Zdrowa J. Trebacz, W. Zajdel Spolka Jawna
  - Krakow, Malopolskie, Polen, 31-315
    - Centrum Medyczne A-Z Clinic
  - Krakow, Malopolskie, Polen, 31-501
    - Krakowskie Centrum Medyczne Sp. z o.o.
  - Krakow, Malopolskie, Polen, 31-202
    - Krakowski Szpital Specjalistyczny im. Jana Pawla II, Oddzial Szybkiej Diagnostyki
  - Krakow, Malopolskie, Polen, 31-531
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie,
  - Myslenice, Malopolskie, Polen, 32-400
    - NeuroCor Banaszkiewicz, Kulaga, Ostrowska, Tomaszewski lekarze spolka partnerska
  - Nowy Targ, Malopolskie, Polen, 34-400
    - INTERCARD Sp. z. o. o. Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii w Nowym Targu
  - Tarnow, Malopolskie, Polen, 33-100
    - Centrum Szybkiej Diagnostyki Kardiologicznej Kardiomed M. Zabowka E. Zabowka
  - Tarnow, Malopolskie, Polen, 33-100
    - Specjalistyczny Gabinet Lekarski Internistyczno-Kardiologiczny Boguslaw Derlaga
- Mazowieckie
  - Katowice, Mazowieckie, Polen, 40-040
    - Synexus Polska Sp. Z O.O. Oddzial W Katowicach
  - Plock, Mazowieckie, Polen, 09-402
    - Niepubliczny Zaklad Opieki Zdrowotnej Specjalistyczna Przychodnia Lekarska "MEDIKARD"
  - Warszawa, Mazowieckie, Polen, 04-730
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego sp. z o.o.
  - Warszawa, Mazowieckie, Polen, 01-875
    - Centrum Medyczne Piaski Filia Nr 9
  - Warszawa, Mazowieckie, Polen, 02-507
    - Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych W Warszawie
  - Warszawa, Mazowieckie, Polen, 02-507
    - CSK MSW w Warszawie, Klinika Kardiologii Zachowawczej i Nadcisnienia Tetniczego
  - Warszawa, Mazowieckie, Polen, 04-141
    - Wojskowy Instytut Medyczny, Klinika Kardiologii i Chorob Wewnetrznych, Centralny Szpital Kliniczny
  - Warszawa, Mazowieckie, Polen, 04-628
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego
- Podkarpackie
  - Brzozow, Podkarpackie, Polen, 36-200
    - Szpital Specjalistyczny w Brzozowie, Podkarpacki Osrodek Onkologiczny im. Ks. B. Markiewicza Oddzial
  - Krosno, Podkarpackie, Polen, 38400
    - INTERCARD Sp. z o.o. Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii w Krosnie
  - Rzeszow, Podkarpackie, Polen, 35205
    - EMED Centrum Uslug Medycznych Ewa Smialek
- Podlaskie
  - Bialystok, Podlaskie, Polen, 15-875
    - Podlaski Osrodek Kardiologii Janusz Korecki
  - Bialystok, Podlaskie, Polen, 15-351
    - """OSTEO-MEDIC"" s.c. Artur Racewicz, Jerzy Supronik"
- Pomorskie
  - Gdansk, Pomorskie, Polen, 80-382
    - Synexus Polska Sp. z o.o. Oddzial w Gdansku
  - Gdansk, Pomorskie, Polen, 80-542
    - Niepubliczny Zaklad Opieki Zdrowotnej Gdanskie Centrum Zdrowia, Poradnia Kardiologiczna
  - Gdansk, Pomorskie, Polen, 80-546
    - Centrum Badan Klinicznych Pi-House, Poradnia Diabetologiczna
  - Gdynia, Pomorskie, Polen, 81-384
    - Synexus Polska Sp. z o.o. Oddzial w Gdyni
  - Gdynia, Pomorskie, Polen, 81-423
    - NZOZ "PRO CORDIS" Sopockie Centrum Badan Kardiologicznych
  - Gdynia, Pomorskie, Polen, 81-472
    - Gabinet Kardiologiczno - lnternistyczny
  - Sopot, Pomorskie, Polen, 81-756
    - Centrum Medyczne "SOPMED" Sp. z o.o.
  - Starogard Gdanski, Pomorskie, Polen, 83-200
    - Indywidualna Specjalistyczna Praktyka Lekarska Malgorzata Biedrzycka
- Slaskie
  - Bytom, Slaskie, Polen, 41-902
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Wojewodzki Szpital Specjalistyczny Nr 4 w Bytomiu,
  - Katowice, Slaskie, Polen, 40-083
    - Bogna Gabrylewicz Andrzej Ochala Unimed s.c.
  - Katowice, Slaskie, Polen, 40-648
    - Pro Familia Altera Poradnia Wielospecjalistyczna
  - Katowice, Slaskie, Polen, 40-752
    - NZOZ Terapia Optima
  - Ruda Slaska, Slaskie, Polen, 41-709
    - Przychodnia Specjalistyczna Samodzielny Publiczny ZOZ w Rudzie Slaskiej, Poradnie Specjalistyczne,
  - Wola, Slaskie, Polen, 43-225
    - NZOZ "Medyk"Sp. z o. o.
- Swietokrzyskie
  - Kielce, Swietokrzyskie, Polen, 25-315
    - Prywatny Gabinet Lekarski Marianna Janion
- Warminsko-mazurskie
  - Elblag, Warminsko-mazurskie, Polen, 82-300
    - Wojewodzki Szpital Zespolony w Elblagu, Oddzial Kardiologiczny z Pododdzialem Kardiologii Inwazyjnej
- Wielkopolskie
  - Poznan, Wielkopolskie, Polen, 60-702
    - Synexus Polska Sp. z o.o Oddzial w Poznaniu
  - Poznan, Wielkopolskie, Polen, 61-006
    - Nzoz "Twoja Przychodnia"
Puerto Rico
- - Anasco, Puerto Rico, 00610
    - The Office of Roberto J. Ayala-Rios, MD - Research Center and Private Practice (DMRA LLC)
  - Ponce, Puerto Rico, 00717
    - Cardiometabolic Research Center, Inc.
  - Ponce, Puerto Rico, 00717
    - Endocrine Lipid Diabetes Research Institute
  - San Juan, Puerto Rico, 00917
    - Pradnet Inc.
  - San Juan, Puerto Rico, 00920
    - Altamira Family Medicine And Research Institute
  - San Juan, Puerto Rico, 00926-2832
    - Miguel Sosa-Padilla, MD-Private Practice
  - San Juan, Puerto Rico, 00935
    - Centro de Diabetes para Puerto Rico
Rumænien
- - Baia Mare, Rumænien, 430032
    - Euromedica Hospital
  - Braila, Rumænien, 810249
    - Spitalul Clinic Judetean De Urgenta Braila(Braila County Clincal Emergency Hospital)
  - Brasov, Rumænien, 500209
    - S.C. Polimed Dacia S.R.L.
  - Brasov, Rumænien, 500283
    - Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL, Medicina Interna
  - Bucharest, Rumænien, 010192
    - Data Plus Medical Clinic
  - Bucharest, Rumænien, 020045
    - "Prof. Dr. N.C. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases,
  - Bucharest, Rumænien, 061118
    - Med Plus SRL (Med Plus Ltd.)
  - Bucharest, Rumænien, 20614
    - S.C. Centrul Medical "Sanatatea Ta" S.R.L.
  - Bucharest, Rumænien, 61118
    - Med Plus Srl
  - Bucuresti, Rumænien, 010825
    - Spitalul Universitar De Urgenta Militar Central, Dr. Carol Davila
  - Bucuresti, Rumænien, 020125
    - Spitalul Clinic Colentina, Departament Cardiologie
  - Bucuresti, Rumænien, 021967
    - SC Centrul Medical Policlinico Di Monza SRL, Cardiologie
  - Bucuresti, Rumænien, 030463
    - SC Policlinica CCBR SRL
  - Cluj-Napoca, Rumænien, 400006
    - Spitalul Clinic Judetean De Urgenta Cluj-Napoca, Diabet Zabarat
  - Cluj-Napoca, Rumænien, 400006
    - Spitalul Clinic Judetean de Urgenta Cluj-Napoca, Diabet Zaharat, Nutritie si Boli Metabolice
  - Galati, Rumænien, 800098
    - Dr. Mistodie Cristina Victoria MD, Office of
  - Galati, Rumænien, 800291
    - S.C. Diamed Obesity S.R.L.
  - Satu Mare, Rumænien, 440055
    - County Emergency Hospital Satu Mare Diabetes, Nutrition And Metabolic Diseases Department
  - Sibiu, Rumænien, 550245
    - County Clinical Emergency Hospital Sibiu
  - Tg. Mures, Rumænien, 540124
    - Cardio Med SRL, Cardiologie
  - Timisoara, Rumænien, 300125
    - Centrul Medical Sf. Stefan
  - Timisoara, Rumænien, 300125
    - Institution Centrul Medical Sf. Stefan SRL, Diabet Nutritie si Boli Metabolice
- Arges
  - Pitesti, Arges, Rumænien, 110084
    - Pitesti-Arges County Emergency Hospital
- Bihor
  - Oradea, Bihor, Rumænien, 410032
    - Medical Practice SRL
  - Oradea, Bihor, Rumænien, 410169
    - County Clinical Emergency Hospital Oradea
- Hunedoara
  - Deva, Hunedoara, Rumænien, 330084
    - County Emergency Hospital Deva
- JUD Maramures
  - Baia Mare, JUD Maramures, Rumænien, 430123
    - CMI Pop Calin Florin
- Judet Timis
  - Timisoara, Judet Timis, Rumænien, 300456
    - Centrul Medical Dr. Negrisanu SRL, Diabet Zaharat Nutritie si Boli Metabolice
- Maramures
  - Baia Mare, Maramures, Rumænien, 430130
    - Dr. Pop Calin Florin - Cabinet Cardiologie
- Mures
  - Targu Mures, Mures, Rumænien, 540143
    - Podoleanu G. Cristian-Gheorghe-Calin - Cardiology Medical Practice
- Prahova
  - Ploiesti, Prahova, Rumænien, 100163
    - Diabmed Dr. Popescu Alexandrina SRL, Diabet, Nutritie, Boli Metabolice
  - Ploiesti, Prahova, Rumænien, 100342
    - Dr. Busegeanu Mihaela Private Practice
- Sectorul 2
  - Bucharest, Sectorul 2, Rumænien, 021611
    - Clinica Medicala Synexus Ltd.
- Timis
  - Timisoara, Timis, Rumænien, 300310
    - Institute of Cardiovascular Diseases Timisoara
Schweiz
- - Lausanne, Schweiz, 1011
    - Centre Hospitalier Universitaire Vaudois
  - Lugano, Schweiz, CH-6900
    - Cardiocentro Ticino
  - Lugano, Schweiz, CH-6900
    - Fondazione Diabete Lugano
  - Luzern 16, Schweiz, CH-6000
    - Luzerner Kantonsspital Luzern
  - St. Gallen, Schweiz, CH-9007
    - Kantonsspital St. Gallen
- Basel
  - Reinach, Basel, Schweiz, 4153
    - Diagene Laboratories Inc.
- Basel Stadt
  - Basel, Basel Stadt, Schweiz, 4031
    - Universitätsspital
- Geneva
  - Geneve, Geneva, Schweiz, 1211
    - Hospitaux Universitaires de Geneve (HUG)
- Vaud
  - Lausanne, Vaud, Schweiz, 1011
    - Policlinique Medicale Universitaire
- Zurich
  - Winterthur, Zurich, Schweiz, 8401
    - Kantonsspital Winterthur
Slovakiet
- - Banska Bystrica, Slovakiet, 974 01
    - Stredoslovensky ustav srdcovych a cievnych chorob a.s.
  - Banska Bystrica, Slovakiet, 97517
    - Fakultna nemocnica F. D. Roosevelta
  - Bardejov, Slovakiet, 08501
    - Alian s.r.o., kardiologicka ambulancia
  - Bratislava, Slovakiet, 81369
    - Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto, l.interna klinika
  - Bratislava, Slovakiet, 81369
    - Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto
  - Bratislava, Slovakiet, 826 06
    - UN Bratislava, Nemocnica Ruzinov, V. interna klinika LFUK a UN Bratislava
  - Bratislava, Slovakiet, 83101
    - Kardiovaskularne Centrum S.R.O.
  - Bratislava, Slovakiet, 83101
    - Metabolicke centrum MUDr. Katariny Raslovej, s.r.o.
  - Bratislava, Slovakiet, 833 48
    - Narodny ustav srdcovych a cievnych chorob, a.s.
  - Bratislava, Slovakiet, 83305
    - Univerzitna nemocnica Bratislava
  - Bratislava, Slovakiet, 83348
    - Narodny ustav srdcovych a cievnych chorob, a.s.
  - Bratislava, Slovakiet, 85101
    - VERIA, s.r.o. -Kardiologicka ambulancia
  - Bratislava, Slovakiet, 811 08
    - Metabol KLINIK s.r.o., Ambulancia pre diabetologiu, poruchy latkovej premeny a vyzivy
  - Bratislava, Slovakiet, 81369
    - Univerzitna nemocnica Bmtislava, Nemocnica Stare Mesto
  - Bratislava, Slovakiet, 841 08
    - KARDIO-SANUS spol.,s.r.o.,Kardiologicka, interna a sonograficka ambulancia
  - Bratislava, Slovakiet, 84107
    - KARDIO-SANUS spol. s.r.o.
  - Bratislava, Slovakiet, 85107
    - UN Bratislava Nemocnica Sv.Cyrila a Metoda, kardiologicka ambulancia 1
  - Dolny Kubin, Slovakiet, 02601
    - Endiamed s.r.o. Nestatna diabetologicka a endokrinologicka ambulancia
  - Dolny Kubin, Slovakiet, 02601
    - JM-Interna s.r.o., interna ambulancia
  - Kosice, Slovakiet, 04011
    - AGTO., spol. s r. o.
  - Kosice, Slovakiet, 04022
    - Cardio D&R spol.s.r.o., kardiologicka ambulancia
  - Kosice, Slovakiet, 040 01
    - CARDIO D&R s.r.o., Kardiologicka ambulancia
  - Kralovsky Chlmec, Slovakiet, 077 01
    - Medicentrum Heart, Spol. S.R.O
  - Levice, Slovakiet, 93405
    - CELL-B s.r.o. interna ambulancia
  - Liptovsky Mikulas, Slovakiet, 031 23
    - Liptovska nemocnica s poliklinikou MUDr.Ivana Stodolu Liptovsky Mikulas
  - Lubochna, Slovakiet, 034 91
    - Narodny Endokrinologicky A Diabetologicky Ustav N.O.
  - Lucenec, Slovakiet, 984 39
    - Kardio 1 S.R.O.
  - Martin, Slovakiet, 036 59
    - Klinika hematologie a transfuziologie, Univerzitna nemocnica Martin
  - Moldava nad Bodvou, Slovakiet, 045 01
    - MEDI M&M s.r.o., Ambulancia vnutorneho lekarstva
  - Namestovo, Slovakiet, 02901
    - MUDr. Kanderkova s.r.o., Diabetologicka ambulancia
  - Nitra, Slovakiet, 94901
    - Kardiocentrum Nitra s.r.o., kardiologicka ambulancia
  - Nove Zamky, Slovakiet, 940 34
    - Fakultna nemocnica s poliklinikou Nove Zamky, I. interna klinika
  - Pezinok, Slovakiet, 90201
    - Mediab s.r.o. Diabetologicka ambulancia
  - Piestany, Slovakiet, 921 01
    - BENIMED s.r.o.
  - Presov, Slovakiet, 08001
    - Medispol s.r.o.
  - Rimavska Sobota, Slovakiet, 979 01
    - Medilex s.r.o. Interna ambulancia
  - Rimavska Sobota, Slovakiet, 97901
    - Kardioamb S.R.O.
  - Trencin, Slovakiet, 911 01
    - DIAMEL, s.r.o., Diabetologicka ambulancia
  - Trnava, Slovakiet, 917 01
    - BV Medical, s.r.o. Diabetologicka ambulancia,
  - Trnava, Slovakiet, 917 01
    - Kardiologicka ambulancia
  - Zilina, Slovakiet, 01001
    - Medivasa s.r.o., Diabetologicka ambulancia
- Bratislavsky
  - Bratislava, Bratislavsky, Slovakiet, 826 06
    - Nemocnica Ruzinov-Univerzitna Nemocnica Bratislava (UNB)
Spanien
- - A Coruna, Spanien, 15006
    - Gerencia de Gestion integrada de A Coruna
  - Albacete, Spanien, 02006
    - Complejo Hospitalario Universitario de Albacete
  - Alicante, Spanien, 03010
    - Hospital General Universitario de Alicante; Servicio Cardiologia
  - Almeria, Spanien, 04120
    - Hospital Virgen del Mar
  - Barcelona, Spanien, 08025
    - Hospital de la Santa Creu i Sant Pau
  - Barcelona, Spanien, 08035
    - Hospital Universitari Vall d'Hebron
  - Barcelona, Spanien, 08003
    - Parc de Salut Mar- Hospital del Mar
  - Barcelona, Spanien, 08907
    - Hospital Universitario de Bellvitge
  - Barcelona, Spanien, 08003
    - Parc de Salut mar ¿ Hospital del Mar
  - Barcelona, Spanien, 08022
    - Centre Teknon
  - Barcelona, Spanien, 08025
    - EAP Sardenya
  - Barcelona, Spanien, 08540
    - CAP Centelles
  - Barcelona, Spanien, 08923
    - Fundacio Hospital de I'Esperit Sant
  - Barcelona, Spanien, 08902
    - CAP Amadeu Torner
  - Cordoba, Spanien, 14004
    - Hospital Universitario Reina Sofia
  - Ferrol, Spanien, 15401
    - Complexo Hospitalario Universitario Arquitecto Marcide-Profesor Novoa Santos De Ferrol
  - Granada, Spanien, 18012
    - Hospital Universitario San Cecilio
  - Granada, Spanien, 18014
    - Hospital Universitario Virgen de las Nieves (HUVN)
  - Lleida, Spanien, 25198
    - Hospital Universitari Arnau de Vilanova
  - Lleida, Spanien, 25198
    - Hospital Universitari Arnau De Vilanova (Huav)
  - Lleida, Spanien, 25198
    - Pharmacy - Hospital Universitari Arnau de Vilanova (HUAV)
  - Lugo, Spanien, 27003
    - Hospital Universitario Lucus Augusti
  - Madrid, Spanien, 28040
    - Fundación Jiménez Díaz
  - Madrid, Spanien, 28034
    - Hospital Universitario Ramón y Cajal
  - Madrid, Spanien, 28040
    - Hospital Universitario Fundación Jiménez Díaz
  - Madrid, Spanien, 28006
    - Hospital Universitario de La Princesa
  - Madrid, Spanien, 28007
    - Hospital General Universitario Gregorio Marañón
  - Madrid, Spanien, 28029
    - Hospital Carlos III
  - Madrid, Spanien, 28046
    - Hospital Universitario La Paz; Unidad Metabolico-Vascular
  - Madrid, Spanien, 28702
    - Hospital Universitario Infanta Sofía
  - Madrid, Spanien, 28805
    - Carretera Alcala-Meco s/n
  - Madrid, Spanien, 28805
    - H. U. Principe de Asturias
  - Malaga, Spanien, 29010
    - Hospital Universitario Virgen de la Victoria
  - Malaga, Spanien, 29009
    - Hospital Regional Universitario de Malaga
  - Malaga, Spanien, 29006
    - Hospital Universitario Virgen de la Victoria. CE San Jose Obrero
  - Murcia, Spanien, 30008
    - Hospital General Universitario Morales Meseguer
  - Reus (Tarragona), Spanien, 43204
    - Hospital Universitario Sant Joan de Reus
  - Sevilla, Spanien, 41009
    - Hospital Universitario Virgen Macarena
  - Sevilla, Spanien, 41014
    - Hospital Universitario Virgen de Valme
  - Sevilla, Spanien, 41003
    - Clínica Nuevas Tecnologías en Diabetes y Endocrinología
  - Tarragona, Spanien, 43002
    - CAP Muralles
  - Valencia, Spanien, 46014
    - Hospital General Universitario de Valencia
  - Zaragoza, Spanien, 50009
    - Hospital Clinico Universitario Miguel Servet; Medicina Interna
- A Coruna
  - Santiago de Compostela, A Coruna, Spanien, 15706
    - Hospital Clinico Universitario de Santiago de Compostela
- Alicante
  - Alcoy, Alicante, Spanien, 03804
    - Hospital Virgen de los Lirios
- Andalucia
  - Malaga, Andalucia, Spanien, 29010
    - Hospital Regional Universitario de Malaga
  - Sevilla, Andalucia, Spanien, 41013
    - Hospital Universitario Virgen del Rocio
- Asturias
  - Oviedo, Asturias, Spanien, 33006
    - Centro de Salud El Cristo
  - Oviedo, Asturias, Spanien, 33009
    - Centro Salud Paulino Prieto
- Barcelona
  - L'Hospitalet de Llobregat, Barcelona, Spanien, 08907
    - Hospital Universitari de Bellvitge
  - Sant Adria De Besos, Barcelona, Spanien, 08930
    - CAP La Mina
  - Vic, Barcelona, Spanien, 08500
    - EAP Vic
- Barcelona-cataluna
  - L'Hospitalet De Llobregat, Barcelona-cataluna, Spanien, 08905
    - CAP Florida
- Barcelona/cataluna
  - El Prat De Llobregat, Barcelona/cataluna, Spanien, 08820
    - CAP Disset De Setembre (Sant Cosme I Sant Damia)
- Cantabria
  - Santander, Cantabria, Spanien, 39008
    - Hospital Universitario Marqués de Valdecilla
- Catalonia
  - Tarragona, Catalonia, Spanien, 43007
    - Hospital Universitari de Tarragona Joan XXIII
- Comunidad Valenciana
  - Alicante, Comunidad Valenciana, Spanien, 03550
    - Hospital Universitario San Juan de Alicante
- Gerona
  - Peralada, Gerona, Spanien, 17491
    - Albera Salut
- Girona
  - Salt, Girona, Girona, Spanien, 17190
    - Hospital Santa Caterina
- Girona-catalonia
  - Figueres, Girona-catalonia, Spanien, 17600
    - Hospital de Figueres
- Illes Balears
  - Inca, Illes Balears, Spanien, 07300
    - Hospital Comarcal d'Inca
- LA Coruna
  - El Ferrol, LA Coruna, Spanien, 15405
    - Hospital Arquitecto Marcide
- Madrid
  - Majadahonda, Madrid, Spanien, 28222
    - Hospital Hospital Universitario Puerta de Hierro - Majadahonda
  - Pozuelo de Alarcon, Madrid, Spanien, 28223
    - Hospital Universitario Quiron Madrid
- PAIS Vasco
  - Barakaldo, PAIS Vasco, Spanien, 48903
    - Hospital Universitario de Cruces
- Tarragona
  - Reus, Tarragona, Spanien, 43204
    - Hospital Universitario Sant Joan de Reus
- Valencia
  - Requena, Valencia, Spanien, 46340
    - Hospital General de Requena
Sverige
- - Eksjö, Sverige, 57535
    - Kasernens Läkarservice AB
  - Goteborg, Sverige, 41345
    - Sahlgrenska Universitetssjukhuset
  - Helsingborg, Sverige, 252 20
    - Pharmasite AB
  - Kristianstad, Sverige, 291 85
    - Medicinklinikens forskningsenhet
  - Lund, Sverige, 222 22
    - Probar E Lund AB
  - Lund, Sverige, 222 21
    - Hjartmottagningen, Capio Citykliniken
  - Malmo, Sverige, 205 02
    - Karlkliniken, Skanes Universitetssjukhus i Malmo
  - Malmo, Sverige, 211 52
    - Pharmasite AB
  - Molndal, Sverige, 431 80
    - Forskningsenheten, Medicinmottagningen Sahlgrenska Universitetssjukhuset/Molndal, Hus J
  - Ostersund, Sverige, 83183
    - Östersunds Sjukhus
  - Rattvik, Sverige, 79530
    - Dalecarlia Clinical Research Center
  - Skelleftea, Sverige, 93186
    - Skellefteå lasarett
  - Stockholm, Sverige, 17176
    - Karolinska Universitetssjukhuset
  - Stockholm, Sverige, 111 57
    - A+Science City site
  - Stockholm, Sverige, 182 82
    - Hjartkliniken
  - Uppsala, Sverige, 75185
    - Akademiska Sjukhuset
  - Vasteras, Sverige, 721 89
    - Västmanlands Sjukhus Västerås
- Huddinge
  - Stockholm, Huddinge, Sverige, 141 86
    - Karolinska Universitetssjukhuset Huddinge
Sydafrika
- - Centurion, Sydafrika, 0157
    - Unitas Hospital.
  - Gauteng, Sydafrika, 1619
    - Clinresco Centres (Pty) Ltd-Central Professional Suits
  - Paarl, Sydafrika, 7646
    - Paarl Research Centre
  - Parow, Sydafrika, 7500
    - TREAD Research CC
  - Worcester, Sydafrika, 6850
    - Clinical Projects Research SA (PTY) LTD
- FREE State
  - Bloemfontein, FREE State, Sydafrika, 9301
    - Josha Research
  - Bloemfontein, FREE State, Sydafrika, 9301
    - Iatros International
  - Welkom, FREE State, Sydafrika, 9460
    - Welkom Clinical Trial Centre
- Gauteng
  - Halfway House, Gauteng, Sydafrika, 1685
    - Midrand Medical Centre
  - Houghton, Gauteng, Sydafrika, 2198
    - Centre for Diabetes and Endocrinology
  - Johannesburg, Gauteng, Sydafrika, 2157
    - Sunninghill Hospital
  - Lyttelton, Gauteng, Sydafrika, 0157
    - I Engelbrecht Research (Pty) Ltd
  - Parktown, Gauteng, Sydafrika, 2193
    - Charlotte Maxeke Johannesburg Academic Hospital
  - Pretoria, Gauteng, Sydafrika, 0184
    - Synexus Watermeyer Clinical Research Centre
  - Pretoria, Gauteng, Sydafrika, 0158
    - Medipark Centre for Clinical Research
  - Pretoria West, Gauteng, Sydafrika, 0183
    - Jongaie Research
  - Roodepoort, Gauteng, Sydafrika, 1724
    - Roodepoort Medicross Clinical Research Centre
  - Soweto, Gauteng, Sydafrika, 2013
    - Wits Clinical Research-Chris Hani Baragwanath Hospital
  - Sunnyside, Gauteng, Sydafrika, 0083
    - Medi-Clinic Heart Hospital
- KWA ZULU Natal
  - Merebank, Durban, KWA ZULU Natal, Sydafrika, 4052
    - Nash Ranjith Research Centre
- Kwazulu-natal
  - Durban, Kwazulu-natal, Sydafrika, 4001
    - Suite 502
  - Durban, Kwazulu-natal, Sydafrika, 4091
    - Dr Ganesh c/o Dr NB Maharaj
- Limpopo
  - Thabazimbi, Limpopo, Sydafrika, 0380
    - Limpopo Clinical Research Initiative
- Mpumalanga
  - Moloto, Mpumalanga, Sydafrika, 1022
    - Zinakekele Medical Centre
  - Witbank (eMalahleni), Mpumalanga, Sydafrika, 1035
    - Drs Joynt Venter & Associates
- Western CAPE
  - Cape Town, Western CAPE, Sydafrika, 7530
    - Tiervlei Trial Centre
  - Cape Town, Western CAPE, Sydafrika, 7130
    - Dr JM Engelbrecht Trial Site-Vergelegen Mediclinic
  - Cape Town, Western CAPE, Sydafrika, 7700
    - Synopsis Research cc
  - Somerset West, Western CAPE, Sydafrika, 7130
    - Helderberg Research Institute
  - Somerset West, Western CAPE, Sydafrika, 7130
    - Synexus Helderberg Clinical Research Centre
  - Somerset West, Western CAPE, Sydafrika, 7130
    - Vergelegen Mediclinic-Helderberg Research Institute
Taiwan
- - Kaohsiung, Taiwan, 807
    - Kaohsiung Medical University Chung-Ho Memorial Hospital - New
  - New Taipei City, Taiwan, 23148
    - Cardinal Tien Hospital
  - Taichung, Taiwan, 402
    - Chung Shan Medical University Hospital
  - Tainan, Taiwan, 70428
    - National Cheng Kung University (NCKU) Hospital
  - Taipei, Taiwan, 11217
    - Taipei Veterans General Hospital
  - Taipei, Taiwan, 10449
    - Mackay Memorial Hospital
  - Taipei, Taiwan, 10041
    - National Taiwan University Hospital
- Taiwan R O C
  - Taichung, Taiwan R O C, Taiwan, 40447
    - China Medical University Hospital
  - Taipei, Taiwan R O C, Taiwan, 10002
    - National Taiwan University Hospital
Thailand
- - Bangkok, Thailand, 10400
    - Cardiology Unit,Department of Medicine, Faculty of Medicine, Ramathibodi Hospital,
  - Bangkok, Thailand, 10400
    - Division Of cardiology,Department of Medicine,Faculty Of Medicine,Chulalongkorn University
- Bangkok
  - Bangkoknoi, Bangkok, Thailand, 10700
    - Division of Cardiology, Department of Medicine, Faculty of Medicine, Siriraj Hospital,
- Khon Kaen
  - Muang, Khon Kaen, Thailand, 40002
    - Faculty of Medicine, Srinagarind Hospital, Khon Kaen University
- Songkla
  - Hat Yai, Songkla, Thailand, 90110
    - Heart Center, Songklanagarind Prince of Songkla University
Tjekkiet
- - Brno, Tjekkiet, 602 00
    - CCBR Czech Brno, s.r.o.
  - Havirov, Tjekkiet, 73601
    - DIKa centrum s.r.o., Kardiologicka a interni ambulance
  - Hradec Kralove, Tjekkiet, 500 05
    - Fakultni nemocnice Hradec Kralove
  - Hradec Kralove, Tjekkiet, 500 05
    - Fakultni nemocnice Hradec Kralove, III. Interni gerontometabolicka klinika
  - Litovel, Tjekkiet, 784 01
    - Kardio Interna s.r.o.
  - Olomouc, Tjekkiet, 77520
    - Fakultni nemocnice Olomouc
  - Olomouc, Tjekkiet, 775 00
    - Fakultni nemocnice Olomouc
  - Pardubice, Tjekkiet, 530 02
    - CCBR Czech a.s.
  - Plzen, Tjekkiet, 326 00
    - Kardiologie Plzen s.r.o.
  - Praha, Tjekkiet, 14059
    - Centrum kardiovaskularni prevence 1. LF UK a TN
  - Praha 2, Tjekkiet, 128 08
    - Fakultní poliklinika Všeobecné fakultní nemocnice v Praze
  - Praha 3, Tjekkiet, 130 00
    - CCBR Czech Prague, s.r.o
  - Praha 5, Tjekkiet, 158 00
    - Kardiologie a interni lekarstvi
  - Praha 6, Tjekkiet, 160 00
    - NEFROMED, s.r.o.
  - Roznov pod Radhostem, Tjekkiet, 756 61
    - Interna a kardiologie s.r.o.
  - Svitavy, Tjekkiet, 568 25
    - Nemocnice Pardubickeho kraje, a.s., Svitavska nemocnice
  - Tabor, Tjekkiet, 390 03
    - Všeobecná kardiologická ambulance s.r.o.
  - Tabor, Tjekkiet, 39003
    - Lekarna U Nemocnice
  - Uherske Hradiste, Tjekkiet, 686 01
    - Lekarna Hradebni s.r.o.
  - Uherske Hradiste 1, Tjekkiet, 686 01
    - MUDr. Antonin Dufka, kardiologicka ambulance
  - Uherske Hradiste 1, Tjekkiet, 686 01
    - MUDr. Nina Zemkova s.r.o.
  - Znojmo, Tjekkiet, 66902
    - KIGE s.r.o.
- Czech Republic
  - Litovel, Czech Republic, Tjekkiet, 78401
    - FREMLOVA APHOTECA s.r.o.
  - Pardubice, Czech Republic, Tjekkiet, 530 02
    - BENU Lekarna
- Jihomoravsky KRAJ
  - Brno, Jihomoravsky KRAJ, Tjekkiet, 638 00
    - Kardiologicka ambulance
- Kralovehradecky KRAJ
  - Broumov, Kralovehradecky KRAJ, Tjekkiet, 55001
    - EDUMED s.r.o.
  - Jaromer, Kralovehradecky KRAJ, Tjekkiet, 550 01
    - EDUMED s.r.o.
  - Trutnov, Kralovehradecky KRAJ, Tjekkiet, 54101
    - Kardiologicka ambulance
  - Trutnov, Kralovehradecky KRAJ, Tjekkiet, 54101
    - Lekarna na Poliklinice
- Moravskoslezsky KRAJ
  - Ostrava, Moravskoslezsky KRAJ, Tjekkiet, 70200
    - MUDr. Jan Vrkoc s.r.o.
- Pardubicky KRAJ
  - Pardubice, Pardubicky KRAJ, Tjekkiet, 53002
    - PV-Kardiologie s.r.o.
Tyskland
- - Altenburg, Tyskland, 04600
    - Klinikum Altenburger Land GmbH
  - Bad Berka, Tyskland, 99437
    - Zentralklinik Bad Berka GmbH
  - Bad Homburg, Tyskland, 61348
    - Forschungszentrum Dr. med Irma Schoell
  - Berlin, Tyskland, 13353
    - Deutsches Herzzentrum Berlin
  - Berlin, Tyskland, 10117
    - Klinische Forschung Berlin-Mitte GmbH
  - Berlin, Tyskland, 12627
    - Synexus Clinical Research GmbH
  - Berlin, Tyskland, 10115
    - Institut fuer Klinische Forschung und Entwicklung(IKFE) Berlin GmbH
  - Berlin, Tyskland, 13597
    - Medizinisches Versorgungszentrum am Bahnhof Spandau
  - Berlin, Tyskland, 12157
    - POLIKUM Institut GmbH
  - Berlin, Tyskland, 12559
    - DRK Kliniken Kopenick, Zentrum Klinische Forschung
  - Berlin, Tyskland, 12627
    - Berlin Research Centre-Synexus Clinical Research GmbH
  - Bielefeld, Tyskland, 33604
    - Klinikum Bielefeld
  - Bochum, Tyskland, 44787
    - Bochum Research Centre-Synexus Clinical Research GmbH
  - Burg-Spreewald, Tyskland, 03096
    - MEDICLIN Reha-Zentrum Spreewald
  - Coburg, Tyskland, 96450
    - Klinikum Coburg
  - Dachau, Tyskland, 85221
    - Helios Amper-Klinikum Dachau
  - Dortmund, Tyskland, 44137
    - St. Johannes-Hospital
  - Dortmund, Tyskland, 44137
    - Kardiologische Praxisgemeinschaft
  - Dortmund, Tyskland, 44141
    - Gemeinschaftspraxis fuer Kardiologie Dres. Med. Willgeroth/Wetzel
  - Dresden, Tyskland, 01069
    - Klinsche Forschung Dresden GmbH
  - Dresden, Tyskland, 01277
    - Praxis Dr. med. Christoph Axthelm
  - Dresden, Tyskland, 01307
    - GWT-TUD GmbH, Studienzentrum Professor Hanefeld
  - Essen, Tyskland, 45355
    - Medizentrum Essen Borbeck
  - Essen, Tyskland, 45355
    - Gemeinschaftspraxis Dr. Hagemann/Breiderhoff/Durfeld
  - Essen, Tyskland, 45355
    - Studienzentrum
  - Essen, Tyskland, 45359
    - Gemeinschaftspraxis Dres. Dirk Weber, Ulrich Weber, Heiner Saueressig, Birte Turner und Georg
  - Falkensee, Tyskland, 14612
    - Schwerpunktpraxis Dr. Luedemann fuer Diabetes Gefaess- und Ernaehrungsmedizin
  - Frankfurt, Tyskland, 60 594
    - ClinPhenomics GmbH & Co KG, Studienzentrum
  - Frankfurt, Tyskland, 60596
    - Synexus Clinical Research GmbH
  - Frankfurt am Main, Tyskland, 60596
    - IKF Institut fuer klinische Forschung Frankfurt
  - Greifswald, Tyskland, 17475
    - Klinik und Poliklinik fuer Innere Medizin B-Kardiologie, Angiologie, Pulmologie, Internistische
  - Hamburg, Tyskland, 22041
    - Cardiologicum Hamburg
  - Hamburg, Tyskland, 22415
    - Praxis Dr. med Cornelia Brauer
  - Hannover, Tyskland, 30159
    - Klinische Forschung Hannover-Mitte GmbH
  - Homburgsaar, Tyskland, 66421
    - Universitätsklinikum des Saarlandes Klinik für Innere Medizin III
  - Kamp-Lintfort, Tyskland, 47475
    - Praxis Dr. Heister
  - Kassel, Tyskland, 34121
    - Studienzentrum Dr. Appel
  - Koeln, Tyskland, 51069
    - Zentrum fuer klinische Forschung
  - Kuenzing, Tyskland, 94550
    - Gemeinschaftspraxis Dr. Klein / Minnich
  - Lahr, Tyskland, 77933
    - Klinik fur Innere Medizin, Kardiologie und Angiologie MediClin Herzzentrum Lahr/Baden.
  - Leipzig, Tyskland, 04249
    - Gemeinschaftspraxis Dr. med. Heidrun Taeschner und Dr. med. Susanne Bonigut
  - Leipzig, Tyskland, 04103
    - Synexus Clinical Research GmbH
  - Leipzig, Tyskland, 04103
    - Synexus Leipzig Clinical Research Centre
  - Leipzig, Tyskland, 04109
    - Polikum Institut Leipzig GmbH
  - Luedenscheid, Tyskland, 58515
    - Maerkische Kliniken GmbH, Klinikum Luedenscheid, Innere III
  - Lunen, Tyskland, 44534
    - Klinikum Lunen, St. Marienhospital
  - Magdeburg, Tyskland, 39120
    - SMO.MD GmbH, Zentrum fuer klinische Studien Site Management and Clinical Research Unit
  - Magdeburg, Tyskland, 39120
    - SMO.MD GmbH - Zentrum fÃ¼r klinische Studien
  - Mainz, Tyskland, 55116
    - Pfuetzner Science & Health Institute-Gmbh
  - Muenchen, Tyskland, 80636
    - Klinikum fuer Herz- & Kreislauferkrankungen
  - Munchen, Tyskland, 80336
    - Klinikum der Universitat Munchen
  - Munich, Tyskland, 81737
    - Staedtisches Klinikum Muenchen GmbH
  - Northeim, Tyskland, 37154
    - Kardiologische Praxis Northeim
  - Nurnberg, Tyskland, 90402
    - Gemeinschaftspraxis Drs Haggenmiller/Jeserich, Kardiologie, Angiologie, Innere Medizin
  - Offenbach, Tyskland, 63071
    - Allgemeinmedizinisch-Internistische Praxisgemeinschaft
  - Rodgau, Tyskland, 63110
    - Praxis Dres. Med Naudts und Nowack
  - Rudersdorf, Tyskland, 15562
    - Klinik am See Rehabilitationszentrum fur Innere Medizin
  - Soest, Tyskland, 59494
    - Kardiologische Gemeinschaftspraxis Dres Med. Gerke/Burger
  - Stuhr-Brinkum, Tyskland, 28816
    - Praxisgemeinschaft Stuhr-Brinkum
  - Stuttgart, Tyskland, 70376
    - Robert-Bosch-Krankenhaus
  - Warendorf, Tyskland, 48231
    - Josephs-Hospital Warendorf Med. Klinik II, Kardiologie/Angiologie
  - Wermsdorf, Tyskland, 04779
    - Kardiologische Praxis
  - Witten, Tyskland, 58455
    - ForschungszentrumRuhr KliFoCenter GmbH
- Baden-wuerttemberg
  - Bad Krozingen, Baden-wuerttemberg, Tyskland, 79189
    - Universitaets Herzzentrum Freiburg Bad Krozingen
- Baden-wurttemberg
  - Heidelberg, Baden-wurttemberg, Tyskland, 69120
    - Medizinische Universtatsklinik Heidelberg
  - Mannheim, Baden-wurttemberg, Tyskland, 68165
    - ze:ro ARZTPRAXEN
- Hessen
  - Fulda, Hessen, Tyskland, 36037
    - Gemeinschaftspraxis im Altstadt Carree
- Mecklenburg-vorpommern
  - Schwerin, Mecklenburg-vorpommern, Tyskland, 19055
    - Klinische Forschung Schwerin GmbH
- Rheinland Pfalz
  - Neuwied, Rheinland Pfalz, Tyskland, 56564
    - Zentrum Klinische Studien Neuwied (ZKSN)
- Rhineland-palatinate
  - Schwabenheim, Rhineland-palatinate, Tyskland, 55270
    - Gemeinschaftspraxis Schwabenheim
Ungarn
- - Balatonfured, Ungarn, 8230
    - DRC Kft.
  - Balatongyorok, Ungarn, 8313
    - DRC Kft.
  - Bekescsaba, Ungarn, 5600
    - Kardiologiai Maganrendelo
  - Berettyoujfalu, Ungarn, 4100
    - Grof Tisza Istvan Korhaz Berettyoujfalu
  - Budapest, Ungarn, 1088
    - Semmelweis Egyetem
  - Budapest, Ungarn, 1096
    - Gottsegen György Országos Kardiológiai Intézet
  - Budapest, Ungarn, 1036
    - Synexus Magyarorszag Kft
  - Budapest, Ungarn, 1125
    - Semmelweis Egyetem
  - Budapest, Ungarn, 1021
    - Budapesti Szent Ferenc Korhaz
  - Budapest, Ungarn, 1085
    - Szent Rokus Korhaz
  - Budapest, Ungarn, 1097
    - Egyesitett Szent Istvan es Szent Laszlo Korhaz-Rendelointezet
  - Budapest, Ungarn, 1125
    - Szent Janos Korhaz es Eszak-budai Egyesitett Korhazak, III. Belgyogyaszat-Kardiologiai Osztaly
  - Budapest, Ungarn, 1097
    - Egyesitett Szent Istvan Korhaz es Szent Laszlo Korhaz
  - Debrecen, Ungarn, 4032
    - Debreceni Egyetem
  - Gyula, Ungarn, 5700
    - Synexus Magyarorszag Kft.
  - Hajduszoboszlo, Ungarn, 4200
    - Edes Szivunk Egeszsegkozpont Kft.
  - Hatvan, Ungarn, 3000
    - BKS Research Kft., Albert Schweitzer Korhaz
  - Kaposvar, Ungarn, 7400
    - Somogy Megyei Kaposi Mor Oktato Korhaz
  - Kecskemet, Ungarn, 6000
    - Jutrix Egeszsegugyi Kft
  - Kistarcsa, Ungarn, 2143
    - Pest Megyei Flor Ferenc Korhaz
  - Kistarcsa, Ungarn, 2143
    - Megyei Flor Ferenc Korhaz
  - Nyiregyhaza, Ungarn, 4400
    - Medifarma-98 Kft.
  - Nyiregyhaza, Ungarn, 4400
    - Jósa András Oktatókórház
  - Pecs, Ungarn, 7624
    - Pecsi Tudomanyegyetem AOK, I. Belgyogyaszati Klinika
  - Szekesfehervar, Ungarn, 8000
    - Mentahaz Maganorvosi Kozpont
  - Szolnok, Ungarn, 5000
    - Hetényi Géza Kórház
  - Szombathely, Ungarn, 9700
    - Markusovszky Egyetemi Oktatokarhaz
  - Veszprem, Ungarn, 8200
    - Dr. Sydo es Tsa Kft.
  - Zalaegerszeg, Ungarn, 8900
    - Zala Megyei Kórház
  - Zalaegerszeg, Ungarn, 8900
    - Zala Megyei Korhaz, Diabetológiai Szakrendelés
- Bacs-kiskun
  - Kecskemet, Bacs-kiskun, Ungarn, 6000
    - Bacs-kiskun Megyei Korhaz
- Baranya
  - Pecs, Baranya, Ungarn, 7624
    - Pecsi Tudomanyegyetem AOK, II.
- Csongrad
  - Szeged, Csongrad, Ungarn, 6720
    - Szegedi Tudomanyegyetem AOK, I. sz Belgyogyaszati Klinika
- Fejer
  - Szekesfehervar, Fejer, Ungarn, 8000
    - Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inklusionskriterier:

Skal være i baggrundslipidsænkende behandling.
Skal have høj risiko for et CV-event.
Skal have en LDL C >/=100 mg/dL (2,6 mmol/L) ELLER ikke HDL C >/= 130 mg/dL (3,4 mmol/L).

Ekskluderingskriterier:

Planlagt koronar (PCI eller CABG) eller anden arteriel revaskularisering.
New York Heart Association klasse IV kongestiv hjerteinsufficiens eller venstre ventrikulær ejektionsfraktion < 25 % ved hjertebilleddannelse.
Kronisk nyreinsufficiens med kreatininclearance på <30 ml/min/1,73m^2 med MDRD-formel eller med sluttilstandsnyresygdom på dialyse.
Anamnese med hæmoragisk slagtilfælde.
Tidligere eksponering for bococizumab eller anden forsøgs-PCSK9-hæmmer.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Forebyggelse
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Firedobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Placebo komparator: Placebo Placebo komparator, hver 2. uge, subkutant.	Medicin: Placebo Placebo komparator, hver 2. uge, subkutant. Varigheden af behandlingsperioden vil afhænge af, at det målrettede antal bedømte og bekræftede CV-udfaldshændelser er nået, cirka 3 til 4 år efter den første forsøgspersons indtræden i undersøgelsen.
Eksperimentel: bococizumab (PF-04950615) 150 mg, hver 2. uge, subkutant.	Medicin: bococizumab (PF-04950615) 150 mg, hver 2. uge, subkutant. Varigheden af behandlingsperioden vil afhænge af, at det målrettede antal bedømte og bekræftede CV-udfaldshændelser er nået, cirka 3 til 4 år efter den første forsøgspersons indtræden i undersøgelsen. Andre navne: RN316

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Hændelsesrate pr. 100 deltagerår for første forekomst af større kardiovaskulær (CV) hændelse Tidsramme: Fra baseline indtil datoen for den første bedømte og bekræftede forekomst af større CV-hændelse (maksimal varighed: op til 3,4 år)	Begivenhedsrate pr. 100 deltagerår for første forekomst af større CV-begivenhed (bedømt af bedømmelseskomitéen) blev rapporteret. Større CV-begivenhed blev defineret som en af følgende: CV-død [defineret som pludselig hjertedød, fatalt myokardieinfarkt (MI), død på grund af hjertesvigt, død på grund af slagtilfælde (fatalt iskæmisk slagtilfælde eller fatalt slagtilfælde af ubestemt ætiologi) eller død på grund af andre CV-årsager] ikke-dødelig MI, ikke-dødelig slagtilfælde og hospitalsindlæggelse for ustabil angina, der har behov for akut revaskularisering. Begivenhedsraten blev beregnet som antallet af begivenheder pr. 100 deltagerår i risikozonen.	Fra baseline indtil datoen for den første bedømte og bekræftede forekomst af større CV-hændelse (maksimal varighed: op til 3,4 år)

Sekundære resultatmål

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Pfizer

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Hjælpsomme links

To obtain contact information for a study center near you, click here.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

29. oktober 2013

Primær færdiggørelse (Faktiske)

3. april 2017

Studieafslutning (Faktiske)

3. april 2017

Datoer for studieregistrering

Først indsendt

21. oktober 2013

Først indsendt, der opfyldte QC-kriterier

28. oktober 2013

Først opslået (Skøn)

3. november 2013

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

1. maj 2019

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

18. april 2019

Sidst verificeret

1. april 2019

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

B1481038
CV OUTCOMES 2 (Alias Study Number)
2013-002795-41 (EudraCT nummer)

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ingen

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Kardiovaskulær sygdom

Ottawa Hospital Research Institute

Afsluttet

Virkningen af uventet død i simulering: Fastholdelse af færdigheder, stress og følelser

Stress | Crisis Resource Management (CRM) færdigheder | Advanced Cardiovascular Life Support (ACLS) færdigheder

Canada

Kliniske forsøg med bococizumab (PF-04950615)

Pfizer

Afsluttet

Randomiseret klinisk forsøg med Bococizumab (PF-04950615; RN316) i forsøgspersoner, der er intolerante over for statiner (SPIRE-SI)

Hyperlipidæmi

Forenede Stater, Canada
Pfizer

Afsluttet

Månedlig og to gange månedlig subkutan dosering af PF-04950615 (RN316) hos hyperkolesterolæmiske forsøgspersoner på et statin

Hyperkolesterolæmi

Forenede Stater
Pfizer

Afsluttet

Farmakokinetik og relativ biotilgængelighed af Bococizumab (PF-04950615; RN316) når det administreres til maven, låret eller overarmen

Hyperkolesterolæmi

Forenede Stater
Pfizer

Afsluttet

Evalueringen af Bococizumab (PF-04950615;RN316) til at reducere forekomsten af større kardiovaskulære hændelser hos højrisikopersoner (SPIRE-1)

Kardiovaskulær sygdom

Finland, Forenede Stater, Holland, Spanien, Korea, Republikken, Kina, Israel, Belgien, Tyskland, Australien, Tjekkiet, Taiwan, Danmark, Det Forenede Kongerige, Ungarn, Polen, Frankrig, Mexico, Kalkun, Canada, New Zealand, Colombia, S... og mere
Pfizer

Afsluttet

Randomiseret klinisk forsøg med Bococizumab (PF-04950615; RN316) hos personer med hyperlipidæmi eller blandet dyslipidæmi med risiko for kardiovaskulære hændelser (SPIRE-LDL)

Hyperlipidæmi

Forenede Stater, Spanien, Taiwan, Det Forenede Kongerige, Canada, Mexico, Frankrig, Ungarn, Litauen, Colombia, Rumænien, Den Russiske Føderation
Pfizer

Afsluttet

En 52-ugers undersøgelse for at vurdere brugen af Bococizumab (PF-04950615; RN316) hos forsøgspersoner med heterozygot familiær hyperkolesterolæmi (SPIRE-FH)

Heterozygot familiær hyperkolesterolæmi

Canada, Holland, Det Forenede Kongerige, Forenede Stater, Spanien, Polen, Finland, Norge, Sydafrika, Italien, Bulgarien
Pfizer

Afsluttet

Randomiseret klinisk forsøg med Bococizumab (PF-04950615; RN316) hos personer med hyperlipidæmi eller blandet dyslipidæmi med risiko for kardiovaskulære hændelser (SPIRE-HR)

Hyperlipidæmi

Korea, Republikken, Forenede Stater, Australien, Tyskland, Polen, Canada, Italien, Hong Kong, Tjekkiet
Pfizer

Afsluttet

Dosisvarierende undersøgelse af Bococizumab (PF-04950615; RN316) hos hyperkolesterolæmiske japanske forsøgspersoner

Hyperkolesterolæmi

Japan
Pfizer

Afsluttet

En farmakokinetisk og farmakodynamisk undersøgelse af PF-04950615 (RN316) hos personer med hyperkolesterolæmi

Metaboliske sygdomme | Dyslipidæmi | Lipidmetabolismeforstyrrelser | Hyperkolesterolæmi | Hyperlipidæmi

Forenede Stater
Pfizer

Afsluttet

Pharmacokinetic And Pharmacodynamic Study Of A Single-Dose Of PF-04950615 (RN316) In Combination With Atorvastatin

Dyslipidæmi | Hyperkolesterolæmi

Forenede Stater

Evalueringen af ​​Bococizumab (PF-04950615; RN316) til at reducere forekomsten af ​​større kardiovaskulære hændelser hos højrisikopersoner (SPIRE-2)

Fase 3 multicenter, dobbeltblind, randomiseret, placebokontrolleret, parallel gruppeevaluering af effektivitet, sikkerhed og tolerabilitet af Bococizumab (Pf-04950615), til at reducere forekomsten af ​​større kardiovaskulære hændelser hos højrisikopersoner

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Publikationer og nyttige links

Generelle publikationer

Hjælpsomme links

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Faktiske)

Studieafslutning (Faktiske)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Skøn)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Kliniske forsøg med Kardiovaskulær sygdom

Kliniske forsøg med bococizumab (PF-04950615)

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Canada

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer

Evalueringen af Bococizumab (PF-04950615; RN316) til at reducere forekomsten af større kardiovaskulære hændelser hos højrisikopersoner (SPIRE-2)

Fase 3 multicenter, dobbeltblind, randomiseret, placebokontrolleret, parallel gruppeevaluering af effektivitet, sikkerhed og tolerabilitet af Bococizumab (Pf-04950615), til at reducere forekomsten af større kardiovaskulære hændelser hos højrisikopersoner