Cold Water Immersion and Recovery (CWI)

Cold Water Immersion as a Strategy to Promote Post-exercise Recovery in Healthy Young Men

Cold-water immersion (CWI) is a frequently applied strategy to accelerate post-exercise recovery in both recreational as well as professional athletes. However, the effect of repeated post-exercise CWI on other recovery strategies remains unclear.

Study Overview

• Status: Completed
• Conditions: Post-exercise Cold Water Immersion
• Intervention / Treatment: Other: Water immersion

• Study Type: Interventional
• Enrollment (Actual): 12
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Netherlands
  • Limburg
    • Maastricht, Limburg, Netherlands, 6200 MD
      • Maastricht University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 35 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Males
• Aged between 18-35 years
• Healthy, recreationally active
• BMI < 25 kg/m2
• The ability to comply with the protocol (i.e. the set-up for the CWI is designed for subjects that are at least 1.70 m or taller).

Exclusion Criteria:

• Smoking
• Allergies to milk proteins (whey or casein)
• Female
• Arthritic conditions
• A history of neuromuscular problems
• Recent (<1 y) participation in amino acid tracer studies
• Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
• Individuals with GI diseases

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Water temperature	Other: Water immersion; Different temperatures of cold water immersion will be assessed

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Muscle protein synthesis (expressed as fractional synthetic rate (FSR in %/h)	2 weeks

Secondary Outcome Measures

Outcome Measure	Time Frame
Muscle temperature (expressed as degrees celsius)	1 day
Glycogen concentration (expressed as micromol glycosol units*g dry wt)	1 day

Collaborators and Investigators

• Sponsor: Maastricht University Medical Center

Publications and helpful links

General Publications

• Gorissen SHM, Trommelen J, Kouw IWK, Holwerda AM, Pennings B, Groen BBL, Wall BT, Churchward-Venne TA, Horstman AMH, Koopman R, Burd NA, Fuchs CJ, Dirks ML, Res PT, Senden JMG, Steijns JMJM, de Groot LCPGM, Verdijk LB, van Loon LJC. Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans. J Nutr. 2020 Aug 1;150(8):2041-2050. doi: 10.1093/jn/nxaa024.

Study record dates

Study Major Dates

• Study Start: November 1, 2015
• Primary Completion (Actual): May 1, 2016
• Study Completion (Actual): May 1, 2016

Study Registration Dates

• First Submitted: November 3, 2015
• First Submitted That Met QC Criteria: November 3, 2015
• First Posted (Estimate): November 4, 2015

Study Record Updates

• Last Update Posted (Estimate): August 2, 2016
• Last Update Submitted That Met QC Criteria: August 1, 2016
• Last Verified: August 1, 2016

More Information

Terms related to this study

• Other Study ID Numbers: METC 153038