Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
March 23, 2026 updated by: NRG Oncology
A Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole Versus Letrozole Monotherapy in Patients With Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum.
Letrozole is an enzyme inhibitor that lowers the amount of estrogen made by the body which in turn may stop the growth of tumor cells that need estrogen to grow.
Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
It is not yet known whether giving letrozole alone or in combination with paclitaxel and carboplatin works better in treating patients with low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum compared to paclitaxel and carboplatin without letrozole.
Study Overview
Status
Active, not recruiting
Conditions
- Stage III Fallopian Tube Cancer AJCC v8
- Stage III Ovarian Cancer AJCC v8
- Stage III Primary Peritoneal Cancer AJCC v8
- Stage IV Fallopian Tube Cancer AJCC v8
- Stage IV Ovarian Cancer AJCC v8
- Stage IV Primary Peritoneal Cancer AJCC v8
- Stage II Fallopian Tube Cancer AJCC v8
- Stage II Ovarian Cancer AJCC v8
- Stage II Primary Peritoneal Cancer AJCC v8
- Low Grade Fallopian Tube Serous Adenocarcinoma
- Ovarian Low Grade Serous Adenocarcinoma
- Primary Peritoneal Low Grade Serous Adenocarcinoma
Detailed Description
PRIMARY OBJECTIVE:
I. To examine if letrozole monotherapy/maintenance (L/L) is non-inferior to intravenous (IV) paclitaxel/carboplatin and maintenance letrozole (CT/L) with respect to progression-free survival (PFS) in women with stage II-IV primary low-grade serous carcinoma of the ovary or peritoneum after primary surgical cytoreduction.
SECONDARY OBJECTIVES:
I. To compare the nature, frequency and maximum degree of toxicity as assessed by Common Terminology Criteria for Adverse Events (CTCAE) version (v) 5.0 for each treatment arm.
II. To compare the relative frequency of objective tumor response in those with measurable disease after cytoreductive surgery for each treatment arm.
III. To compare overall survival for each treatment arm. IV. To compare the CT/L and L/L arms with respect to patients' adherence to letrozole therapy as measured by pill counts.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients receive paclitaxel IV over 3 hours and carboplatin IV on day 1. Cycles repeat every 21 days for up to 6 cycles. Patients then receive letrozole orally (PO) once daily (QD) in the absence of disease progression or unacceptable toxicity. Patients undergo blood collection and tumor biopsy during screening as well as medical imaging throughout the study.
ARM II: Patients receive letrozole PO QD. Cycles repeat every 21 days for up to 6 cycles. Patients then receive letrozole orally PO QD in the absence of disease progression or unacceptable toxicity as maintenance therapy. Patients undergo blood collection and tumor biopsy during screening as well as medical imaging throughout the study.
After completion of study treatment/intervention, patients/participants are followed up every 3 months for 1 year, then every 6 months for 3 years, then annually thereafter.
Study Type
Interventional
Enrollment (Estimated)
450
Phase
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Ontario
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Toronto, Ontario, Canada, M5G 2M9
- University Health Network-Princess Margaret Hospital
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Toronto, Ontario, Canada, M4N 3M5
- Odette Cancer Centre- Sunnybrook Health Sciences Centre
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Quebec
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Montreal, Quebec, Canada, H2X 3E4
- CHUM - Centre Hospitalier de l'Universite de Montreal
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Saskatchewan
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Regina, Saskatchewan, Canada, S4T 7T1
- Allan Blair Cancer Centre
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Saskatoon, Saskatchewan, Canada, S7N 4H4
- Saskatoon Cancer Centre
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Cork, Ireland
- Cork University Hospital
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Dublin, Ireland, 8
- Saint James Hospital
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Lima, Peru, Lima 34
- Instituto Nacional de Enfermedades Neoplasicas
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Bayamón, Puerto Rico, 00959-5060
- Cancer Center-Metro Medical Center Bayamon
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Bayamón, Puerto Rico, 00961
- Puerto Rico Hematology Oncology Group
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Caguas, Puerto Rico, 00726
- HIMA San Pablo Oncologic Hospital
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Manatí, Puerto Rico, 00674
- Doctors Cancer Center
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Ponce, Puerto Rico, 00716
- Instituto Oncologia Moderna Ponce
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San Juan, Puerto Rico, 00917
- San Juan Community Oncology Group
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San Juan, Puerto Rico, 00927
- Centro Comprensivo de Cancer de UPR
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San Juan, Puerto Rico, 00936
- San Juan City Hospital
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San Juan, Puerto Rico, 00920
- Primary Care Physician Group
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San Juan, Puerto Rico, 00927
- PROncology
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Daegu, South Korea, 41404
- Kyungpook National University Chilgok Hospital
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Incheon, South Korea, 405-760
- Gachon University Gil Hospital
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Seoul, South Korea, 05505
- Asan Medical Center
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Seoul, South Korea, 06273
- Gangnam Severance Hospital
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Seoul, South Korea, 139-706
- Korea Cancer Center Hospital
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Gyeonggi-do
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Goyang-si, Gyeonggi-do, South Korea, 410-769
- National Cancer Center-Korea
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Gyeongsangnam-do
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Seoul, Gyeongsangnam-do, South Korea, 51353
- Samsung Changwon Hospital
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Kyeonggi-do
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Seongnam, Kyeonggi-do, South Korea, 463-707
- Seoul National University Bundang Hospital
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Alaska
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Anchorage, Alaska, United States, 98508
- Anchorage Associates in Radiation Medicine
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Anchorage, Alaska, United States, 99508
- Alaska Breast Care and Surgery LLC
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Anchorage, Alaska, United States, 99508
- Alaska Oncology and Hematology LLC
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Anchorage, Alaska, United States, 99508
- Alaska Women's Cancer Care
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Anchorage, Alaska, United States, 99508
- Anchorage Oncology Centre
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Anchorage, Alaska, United States, 99508
- Katmai Oncology Group
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Anchorage, Alaska, United States, 99508
- Providence Alaska Medical Center
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Anchorage, Alaska, United States, 99504
- Anchorage Radiation Therapy Center
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Fairbanks, Alaska, United States, 99701
- Fairbanks Memorial Hospital
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Arizona
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Goodyear, Arizona, United States, 85338
- CTCA at Western Regional Medical Center
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Kingman, Arizona, United States, 86401
- Kingman Regional Medical Center
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Phoenix, Arizona, United States, 85004
- Cancer Center at Saint Joseph's
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Tucson, Arizona, United States, 85704
- University of Arizona Cancer Center-Orange Grove Campus
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Tucson, Arizona, United States, 85719
- Banner University Medical Center - Tucson
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Tucson, Arizona, United States, 85719
- University of Arizona Cancer Center-North Campus
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Arkansas
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Fort Smith, Arkansas, United States, 72903
- Mercy Hospital Fort Smith
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Hot Springs, Arkansas, United States, 71913
- CHI Saint Vincent Cancer Center Hot Springs
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Jonesboro, Arkansas, United States, 72401
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
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Little Rock, Arkansas, United States, 72205
- University of Arkansas for Medical Sciences
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Little Rock, Arkansas, United States, 72205
- CARTI Cancer Center
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California
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Antioch, California, United States, 94531
- Kaiser Permanente-Deer Valley Medical Center
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Arroyo Grande, California, United States, 93420
- PCR Oncology
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Arroyo Grande, California, United States, 93420
- Mission Hope Medical Oncology - Arroyo Grande
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Auburn, California, United States, 95602
- Sutter Auburn Faith Hospital
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Auburn, California, United States, 95603
- Sutter Cancer Centers Radiation Oncology Services-Auburn
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Bellflower, California, United States, 90706
- Kaiser Permanente-Bellflower
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Berkeley, California, United States, 94704
- Alta Bates Summit Medical Center-Herrick Campus
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Buena Park, California, United States, 90621
- Keck Medicine of USC Buena Park
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Burbank, California, United States, 91505
- Providence Saint Joseph Medical Center/Disney Family Cancer Center
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Burlingame, California, United States, 94010
- Mills-Peninsula Medical Center
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Cameron Park, California, United States, 95682
- Sutter Cancer Centers Radiation Oncology Services-Cameron Park
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Carmichael, California, United States, 95608
- Mercy San Juan Medical Center
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Carmichael, California, United States, 95608
- Mercy Cancer Center - Carmichael
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Castro Valley, California, United States, 94546
- Eden Hospital Medical Center
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Clovis, California, United States, 93611
- Community Cancer Institute
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Clovis, California, United States, 93611
- University Oncology Associates
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Davis, California, United States, 95616
- Sutter Davis Hospital
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Duarte, California, United States, 91010
- City of Hope Comprehensive Cancer Center
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Dublin, California, United States, 94568
- Kaiser Permanente Dublin
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Elk Grove, California, United States, 95758
- Mercy Cancer Center - Elk Grove
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Fremont, California, United States, 94538
- Kaiser Permanente-Fremont
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Fremont, California, United States, 94538
- Palo Alto Medical Foundation-Fremont
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Fresno, California, United States, 93720
- Kaiser Permanente-Fresno
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Fresno, California, United States, 93720
- Fresno Cancer Center
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Harbor City, California, United States, 90710
- Kaiser Permanente South Bay
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Huntington Beach, California, United States, 92648
- Keck Medicine of USC Huntington Beach
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Huntington Beach, California, United States, 92648
- City of Hope Seacliff
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Irvine, California, United States, 92618
- Kaiser Permanente-Irvine
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Irvine, California, United States, 92618
- City of Hope at Irvine Lennar
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Loma Linda, California, United States, 92354
- Loma Linda University Medical Center
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Los Angeles, California, United States, 90033
- USC / Norris Comprehensive Cancer Center
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Los Angeles, California, United States, 90027
- Kaiser Permanente Los Angeles Medical Center
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Los Angeles, California, United States, 90034
- Kaiser Permanente West Los Angeles
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Los Angeles, California, United States, 90020
- Keck Medicine of USC Koreatown
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Los Angeles, California, United States, 90033
- Los Angeles General Medical Center
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Martinez, California, United States, 94553-3156
- Contra Costa Regional Medical Center
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Merced, California, United States, 95340
- Mercy Cancer Center
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Modesto, California, United States, 95355
- Memorial Medical Center
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Modesto, California, United States, 95356
- Kaiser Permanente-Modesto
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Mountain View, California, United States, 94040
- Palo Alto Medical Foundation-Camino Division
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Mountain View, California, United States, 94040
- Palo Alto Medical Foundation-Gynecologic Oncology
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Napa, California, United States, 94558
- Providence Queen of The Valley
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Newport Beach, California, United States, 92663
- USC Norris Oncology/Hematology-Newport Beach
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Novato, California, United States, 94945
- Sutter Cancer Research Consortium
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Oakland, California, United States, 94611
- Kaiser Permanente-Oakland
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Oakland, California, United States, 94611
- Kaiser Permanente Oakland-Broadway
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Palo Alto, California, United States, 94301
- Palo Alto Medical Foundation Health Care
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Panorama City, California, United States, 91402
- Kaiser Permanente - Panorama City
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Pasadena, California, United States, 91105
- Keck Medical Center of USC Pasadena
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Rancho Cordova, California, United States, 95670
- Kaiser Permanente-Rancho Cordova Cancer Center
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Redwood City, California, United States, 94063
- Kaiser Permanente-Redwood City
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Redwood City, California, United States, 94063
- Kaiser Permanente- Marshall Medical Offices
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Richmond, California, United States, 94801
- Kaiser Permanente-Richmond
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Riverside, California, United States, 92505
- Kaiser Permanente-Riverside
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Rocklin, California, United States, 95765
- Mercy Cancer Center - Rocklin
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Rohnert Park, California, United States, 94928
- Rohnert Park Cancer Center
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Roseville, California, United States, 95678
- The Permanente Medical Group-Roseville Radiation Oncology
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Roseville, California, United States, 95661
- Kaiser Permanente-Roseville
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Roseville, California, United States, 95661
- Sutter Cancer Centers Radiation Oncology Services-Roseville
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Roseville, California, United States, 95661
- Sutter Roseville Medical Center
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Sacramento, California, United States, 95816
- Sutter Medical Center Sacramento
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Sacramento, California, United States, 95814
- Kaiser Permanente Downtown Commons
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Sacramento, California, United States, 95823
- Kaiser Permanente-South Sacramento
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Sacramento, California, United States, 95823
- South Sacramento Cancer Center
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Sacramento, California, United States, 95816
- Mercy Cancer Center - Sacramento
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San Diego, California, United States, 92120
- Kaiser Permanente-San Diego Zion
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San Francisco, California, United States, 94115
- Kaiser Permanente-San Francisco
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San Francisco, California, United States, 94158
- UCSF Medical Center-Mission Bay
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San Francisco, California, United States, 94115
- California Pacific Medical Center-Pacific Campus
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San Jose, California, United States, 95119
- Kaiser Permanente-Santa Teresa-San Jose
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San Leandro, California, United States, 94577
- Kaiser Permanente San Leandro
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San Luis Obispo, California, United States, 93401
- Pacific Central Coast Health Center-San Luis Obispo
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San Marcos, California, United States, 92078
- Kaiser Permanente-San Marcos
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San Mateo, California, United States, 94401
- Mills Health Center
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San Rafael, California, United States, 94903
- Kaiser San Rafael-Gallinas
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Santa Barbara, California, United States, 93105
- Ridley-Tree Cancer Center
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Santa Clara, California, United States, 95051
- Kaiser Permanente Medical Center - Santa Clara
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Santa Cruz, California, United States, 95065
- Palo Alto Medical Foundation-Santa Cruz
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Santa Cruz, California, United States, 95065
- Santa Cruz Radiation Oncology Medical Group
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Santa Maria, California, United States, 93444
- Mission Hope Medical Oncology - Santa Maria
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Santa Rosa, California, United States, 95403
- Kaiser Permanente-Santa Rosa
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Santa Rosa, California, United States, 95403
- Sutter Pacific Medical Foundation
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Santa Rosa, California, United States, 95403
- Providence Medical Foundation - Santa Rosa
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Santa Rosa, California, United States, 95405
- Providence Santa Rosa Memorial Hospital
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South Pasadena, California, United States, 91030
- City of Hope South Pasadena
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South San Francisco, California, United States, 94080
- Kaiser Permanente Cancer Treatment Center
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South San Francisco, California, United States, 94080
- Kaiser Permanente-South San Francisco
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Stockton, California, United States, 95210
- Kaiser Permanente-Stockton
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Stockton, California, United States, 95204
- Saint Joseph's Medical Center
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Sunnyvale, California, United States, 94086
- Palo Alto Medical Foundation-Sunnyvale
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Upland, California, United States, 91786
- City of Hope Upland
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Vacaville, California, United States, 95688
- Kaiser Permanente Medical Center-Vacaville
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Vallejo, California, United States, 94589
- Kaiser Permanente-Vallejo
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Vallejo, California, United States, 94589
- Sutter Solano Medical Center/Cancer Center
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Walnut Creek, California, United States, 94596
- Kaiser Permanente-Walnut Creek
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Walnut Creek, California, United States, 94598
- BASS Medical Group - Lennon
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Woodland, California, United States, 95695
- Woodland Memorial Hospital
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Woodland Hills, California, United States, 91367
- Kaiser Permanente-Woodland Hills
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Colorado
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Aurora, Colorado, United States, 80012
- Rocky Mountain Cancer Centers-Aurora
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Aurora, Colorado, United States, 80012
- The Medical Center of Aurora
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Aurora, Colorado, United States, 80045
- UCHealth University of Colorado Hospital
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Boulder, Colorado, United States, 80303
- Boulder Community Foothills Hospital
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Boulder, Colorado, United States, 80304
- Rocky Mountain Cancer Centers-Boulder
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Centennial, Colorado, United States, 80112
- Rocky Mountain Cancer Centers - Centennial
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Colorado Springs, Colorado, United States, 80907
- Penrose-Saint Francis Healthcare
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Colorado Springs, Colorado, United States, 80907
- Rocky Mountain Cancer Centers-Penrose
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Colorado Springs, Colorado, United States, 80923
- Saint Francis Cancer Center
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Denver, Colorado, United States, 80218
- Presbyterian - Saint Lukes Medical Center - Health One
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Denver, Colorado, United States, 80220
- Rose Medical Center
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Denver, Colorado, United States, 80218
- Rocky Mountain Cancer Centers-Midtown
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Denver, Colorado, United States, 80220
- Rocky Mountain Cancer Centers-Rose
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Denver, Colorado, United States, 80218
- Colorado Blood Cancer Institute
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Denver, Colorado, United States, 80204
- Cancer Center of Colorado at Sloan's Lake
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Denver, Colorado, United States, 80209
- The Women's Imaging Center
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Denver, Colorado, United States, 80206
- National Jewish Health-Main Campus
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Denver, Colorado, United States, 80220
- Western Surgical Care
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Denver, Colorado, United States, 80218
- Saint Joseph Hospital - Cancer Centers of Colorado
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Denver, Colorado, United States, 80210
- AdventHealth Porter
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Durango, Colorado, United States, 81301
- Mercy Medical Center
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Durango, Colorado, United States, 81301
- CommonSpirit Cancer Center Mercy
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Englewood, Colorado, United States, 80113
- Mountain Blue Cancer Care Center - Swedish
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Englewood, Colorado, United States, 80113
- Swedish Medical Center
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Englewood, Colorado, United States, 80113
- Rocky Mountain Cancer Centers - Swedish
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Englewood, Colorado, United States, 80113
- The Melanoma and Skin Cancer Institute
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Golden, Colorado, United States, 80401
- National Jewish Health-Western Hematology Oncology
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Grand Junction, Colorado, United States, 81501
- Saint Mary's Hospital and Regional Medical Center
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Lafayette, Colorado, United States, 80026
- Good Samaritan Hospital - Cancer Centers of Colorado
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Lakewood, Colorado, United States, 80228
- Saint Anthony Hospital
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Lakewood, Colorado, United States, 80228
- Rocky Mountain Cancer Centers-Lakewood
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Littleton, Colorado, United States, 80120
- Rocky Mountain Cancer Centers-Littleton
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Littleton, Colorado, United States, 80122
- AdventHealth Littleton
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Lone Tree, Colorado, United States, 80124
- Sky Ridge Medical Center
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Lone Tree, Colorado, United States, 80124
- Rocky Mountain Cancer Centers-Sky Ridge
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Longmont, Colorado, United States, 80501
- Longmont United Hospital
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Longmont, Colorado, United States, 80501
- Rocky Mountain Cancer Centers-Longmont
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Parker, Colorado, United States, 80138
- AdventHealth Parker
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Pueblo, Colorado, United States, 81004
- Saint Mary Corwin Medical Center
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Thornton, Colorado, United States, 80260
- Rocky Mountain Cancer Centers-Thornton
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Thornton, Colorado, United States, 80260
- National Jewish Health-Northern Hematology Oncology
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Westminster, Colorado, United States, 80023
- Saint Anthony North Hospital
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Wheat Ridge, Colorado, United States, 80401
- Intermountain Health Lutheran Hospital
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Connecticut
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Danbury, Connecticut, United States, 06810
- Danbury Hospital
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Derby, Connecticut, United States, 06418
- Smilow Cancer Hospital-Derby Care Center
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Fairfield, Connecticut, United States, 06824
- Smilow Cancer Hospital Care Center-Fairfield
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Greenwich, Connecticut, United States, 06830
- Smilow Cancer Hospital Care Center at Greenwich
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Guilford, Connecticut, United States, 06437
- Smilow Cancer Hospital Care Center - Guilford
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Hartford, Connecticut, United States, 06105
- Smilow Cancer Hospital Care Center at Saint Francis
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Hartford, Connecticut, United States, 06102
- Hartford Hospital
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New Britain, Connecticut, United States, 06050
- The Hospital of Central Connecticut
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New Haven, Connecticut, United States, 06520
- Yale University
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New Haven, Connecticut, United States, 06510
- Smilow Cancer Center/Yale-New Haven Hospital
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North Haven, Connecticut, United States, 06473
- Yale-New Haven Hospital North Haven Medical Center
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Norwalk, Connecticut, United States, 06856
- Norwalk Hospital
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Orange, Connecticut, United States, 06477
- Smilow Cancer Hospital-Orange Care Center
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Torrington, Connecticut, United States, 06790
- Smilow Cancer Hospital-Torrington Care Center
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Trumbull, Connecticut, United States, 06611
- Smilow Cancer Hospital Care Center-Trumbull
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Waterbury, Connecticut, United States, 06708
- Smilow Cancer Hospital-Waterbury Care Center
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Waterford, Connecticut, United States, 06385
- Smilow Cancer Hospital Care Center - Waterford
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Delaware
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Lewes, Delaware, United States, 19958
- Beebe Medical Center
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Millville, Delaware, United States, 19967
- Beebe South Coastal Health Campus
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Newark, Delaware, United States, 19713
- Helen F Graham Cancer Center
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Newark, Delaware, United States, 19713
- Delaware Clinical and Laboratory Physicians PA
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Newark, Delaware, United States, 19713
- Medical Oncology Hematology Consultants PA
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Newark, Delaware, United States, 19718
- Christiana Care Health System-Christiana Hospital
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Rehoboth Beach, Delaware, United States, 19971
- Beebe Health Campus
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Seaford, Delaware, United States, 19973
- TidalHealth Nanticoke / Allen Cancer Center
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Wilmington, Delaware, United States, 19801
- Christiana Care Health System-Wilmington Hospital
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District of Columbia
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Washington D.C., District of Columbia, United States, 20037
- George Washington University Medical Center
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Washington D.C., District of Columbia, United States, 20016
- Sibley Memorial Hospital
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Florida
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Fort Lauderdale, Florida, United States, 33316
- Broward Health Medical Center
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Fort Lauderdale, Florida, United States, 33308
- Holy Cross Hospital
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Fort Myers, Florida, United States, 33905
- Regional Cancer Center-Lee Memorial Health System
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Fort Myers, Florida, United States, 33905
- GenesisCare USA - FGO
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Jacksonville, Florida, United States, 32207
- Baptist MD Anderson Cancer Center
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Georgia
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Atlanta, Georgia, United States, 30342
- Northside Hospital
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Augusta, Georgia, United States, 30912
- Augusta University Medical Center
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Newnan, Georgia, United States, 30265
- CTCA at Southeastern Regional Medical Center
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Savannah, Georgia, United States, 31405
- Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
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Hawaii
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Honolulu, Hawaii, United States, 96813
- Queen's Medical Center
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Honolulu, Hawaii, United States, 96817
- The Cancer Center of Hawaii-Liliha
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Honolulu, Hawaii, United States, 96813
- Hawaii Cancer Care Inc - Waterfront Plaza
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Honolulu, Hawaii, United States, 96813
- Queen's Cancer Cenrer - POB I
-
Honolulu, Hawaii, United States, 96813
- Straub Clinic and Hospital
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Honolulu, Hawaii, United States, 96813
- University of Hawaii Cancer Center
-
Honolulu, Hawaii, United States, 96817
- Hawaii Cancer Care Inc-Liliha
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Honolulu, Hawaii, United States, 96817
- Kuakini Medical Center
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Honolulu, Hawaii, United States, 96817
- Queen's Cancer Center - Kuakini
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Honolulu, Hawaii, United States, 96826
- Kapiolani Medical Center for Women and Children
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Honolulu, Hawaii, United States, 96813
- Island Urology
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Honolulu, Hawaii, United States, 96819
- Kaiser Permanente Moanalua Medical Center
-
Lihue, Hawaii, United States, 96766
- Wilcox Memorial Hospital and Kauai Medical Clinic
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‘Aiea, Hawaii, United States, 96701
- Hawaii Cancer Care - Westridge
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‘Aiea, Hawaii, United States, 96701
- Pali Momi Medical Center
-
‘Aiea, Hawaii, United States, 96701
- Queen's Cancer Center - Pearlridge
-
‘Aiea, Hawaii, United States, 96701
- The Cancer Center of Hawaii-Pali Momi
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‘Ewa Beach, Hawaii, United States, 96706
- The Queen's Medical Center - West Oahu
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Idaho
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Boise, Idaho, United States, 83706
- Saint Alphonsus Cancer Care Center-Boise
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Boise, Idaho, United States, 83712
- Saint Luke's Cancer Institute - Boise
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Caldwell, Idaho, United States, 83605
- Saint Alphonsus Cancer Care Center-Caldwell
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Coeur d'Alene, Idaho, United States, 83814
- Kootenai Health - Coeur d'Alene
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Emmett, Idaho, United States, 83617
- Walter Knox Memorial Hospital
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Fruitland, Idaho, United States, 83619
- Saint Luke's Cancer Institute - Fruitland
-
Meridian, Idaho, United States, 83642
- Idaho Urologic Institute-Meridian
-
Meridian, Idaho, United States, 83642
- Saint Luke's Cancer Institute - Meridian
-
Nampa, Idaho, United States, 83687
- Saint Alphonsus Cancer Care Center-Nampa
-
Nampa, Idaho, United States, 83687
- Saint Luke's Cancer Institute - Nampa
-
Post Falls, Idaho, United States, 83854
- Kootenai Clinic Cancer Services - Post Falls
-
Sandpoint, Idaho, United States, 83864
- Kootenai Clinic Cancer Services - Sandpoint
-
Twin Falls, Idaho, United States, 83301
- Saint Luke's Cancer Institute - Twin Falls
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Illinois
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Alton, Illinois, United States, 62002
- OSF Saint Anthony's Health Center
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Aurora, Illinois, United States, 60504
- Rush-Copley Medical Center
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Aurora, Illinois, United States, 60506
- Advocate Outpatient Center - Aurora
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Barrington, Illinois, United States, 60010
- Advocate Good Shepherd Hospital
-
Bloomington, Illinois, United States, 61704
- Illinois CancerCare-Bloomington
-
Canton, Illinois, United States, 61520
- Illinois CancerCare-Canton
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Carbondale, Illinois, United States, 62902
- Memorial Hospital of Carbondale
-
Carterville, Illinois, United States, 62918
- SIH Cancer Institute
-
Carthage, Illinois, United States, 62321
- Illinois CancerCare-Carthage
-
Centralia, Illinois, United States, 62801
- Centralia Oncology Clinic
-
Centralia, Illinois, United States, 62801
- Saint Mary's Hospital
-
Chicago, Illinois, United States, 60611
- Northwestern University
-
Chicago, Illinois, United States, 60637
- University of Chicago Comprehensive Cancer Center
-
Chicago, Illinois, United States, 60612
- John H Stroger Jr Hospital of Cook County
-
Chicago, Illinois, United States, 60657
- Advocate Illinois Masonic Medical Center
-
Crystal Lake, Illinois, United States, 60014
- AMG Crystal Lake - Oncology
-
Danville, Illinois, United States, 61832
- Carle at The Riverfront
-
DeKalb, Illinois, United States, 60115
- Northwestern Medicine Cancer Center Kishwaukee
-
Decatur, Illinois, United States, 62526
- Decatur Memorial Hospital
-
Decatur, Illinois, United States, 62526
- Cancer Care Specialists of Illinois - Decatur
-
Dixon, Illinois, United States, 61021
- Illinois CancerCare-Dixon
-
Downers Grove, Illinois, United States, 60515
- Advocate Good Samaritan Hospital
-
Effingham, Illinois, United States, 62401
- Crossroads Cancer Center
-
Effingham, Illinois, United States, 62401
- Carle Physician Group-Effingham
-
Elgin, Illinois, United States, 60123
- Advocate Sherman Hospital
-
Eureka, Illinois, United States, 61530
- Illinois CancerCare-Eureka
-
Evanston, Illinois, United States, 60201
- NorthShore University HealthSystem-Evanston Hospital
-
Galesburg, Illinois, United States, 61401
- Western Illinois Cancer Treatment Center
-
Galesburg, Illinois, United States, 61401
- Illinois CancerCare-Galesburg
-
Geneva, Illinois, United States, 60134
- Northwestern Medicine Cancer Center Delnor
-
Glenview, Illinois, United States, 60026
- NorthShore University HealthSystem-Glenbrook Hospital
-
Glenview, Illinois, United States, 60026
- Northwestern Medicine Glenview Outpatient Center
-
Grayslake, Illinois, United States, 60030
- Northwestern Medicine Grayslake Outpatient Center
-
Hazel Crest, Illinois, United States, 60429
- Advocate South Suburban Hospital
-
Highland Park, Illinois, United States, 60035
- NorthShore University HealthSystem-Highland Park Hospital
-
Hinsdale, Illinois, United States, 60521
- Sudarshan K Sharma MD Limited-Gynecologic Oncology
-
Kewanee, Illinois, United States, 61443
- Illinois CancerCare-Kewanee Clinic
-
Lake Forest, Illinois, United States, 60045
- Northwestern Medicine Lake Forest Hospital
-
Libertyville, Illinois, United States, 60048
- Condell Memorial Hospital
-
Libertyville, Illinois, United States, 60048
- AMG Libertyville - Oncology
-
Macomb, Illinois, United States, 61455
- Illinois CancerCare-Macomb
-
Mattoon, Illinois, United States, 61938
- Carle Physician Group-Mattoon/Charleston
-
Mount Vernon, Illinois, United States, 62864
- SSM Health Good Samaritan
-
New Lenox, Illinois, United States, 60451
- UC Comprehensive Cancer Center at Silver Cross
-
O'Fallon, Illinois, United States, 62269
- Cancer Care Center of O'Fallon
-
Oak Lawn, Illinois, United States, 60453-2699
- Advocate Christ Medical Center
-
Orland Park, Illinois, United States, 60462
- University of Chicago Medicine-Orland Park
-
Orland Park, Illinois, United States, 60462
- Northwestern Medicine Orland Park
-
Ottawa, Illinois, United States, 61350
- Illinois CancerCare-Ottawa Clinic
-
Park Ridge, Illinois, United States, 60068
- Advocate Lutheran General Hospital
-
Pekin, Illinois, United States, 61554
- Illinois CancerCare-Pekin
-
Peoria, Illinois, United States, 61636
- Methodist Medical Center of Illinois
-
Peoria, Illinois, United States, 61615
- Illinois CancerCare-Peoria
-
Peru, Illinois, United States, 61354
- Illinois CancerCare-Peru
-
Peru, Illinois, United States, 61354
- Valley Radiation Oncology
-
Princeton, Illinois, United States, 61356
- Illinois CancerCare-Princeton
-
Springfield, Illinois, United States, 62702
- Southern Illinois University School of Medicine
-
Springfield, Illinois, United States, 62702
- Springfield Clinic
-
Springfield, Illinois, United States, 62781
- Springfield Memorial Hospital
-
Swansea, Illinois, United States, 62226
- Southwest Illinois Health Services LLP
-
Urbana, Illinois, United States, 61801
- Carle Cancer Center
-
Urbana, Illinois, United States, 61801
- The Carle Foundation Hospital
-
Warrenville, Illinois, United States, 60555
- Northwestern Medicine Cancer Center Warrenville
-
Washington, Illinois, United States, 61571
- Illinois CancerCare - Washington
-
Yorkville, Illinois, United States, 60560
- Rush-Copley Healthcare Center
-
Zion, Illinois, United States, 60099
- Midwestern Regional Medical Center
-
-
Indiana
-
Carmel, Indiana, United States, 46032
- IU Health North Hospital
-
Fort Wayne, Indiana, United States, 46845
- Parkview Regional Medical Center
-
Goshen, Indiana, United States, 46526
- Goshen Center for Cancer Care
-
Indianapolis, Indiana, United States, 46202
- Indiana University/Melvin and Bren Simon Cancer Center
-
Indianapolis, Indiana, United States, 46260
- Ascension Saint Vincent Indianapolis Hospital
-
Indianapolis, Indiana, United States, 46202
- Sidney and Lois Eskenazi Hospital
-
Richmond, Indiana, United States, 47374
- Reid Health
-
South Bend, Indiana, United States, 46601
- Memorial Hospital of South Bend
-
-
Iowa
-
Ames, Iowa, United States, 50010
- Mary Greeley Medical Center
-
Ames, Iowa, United States, 50010
- McFarland Clinic - Ames
-
Ankeny, Iowa, United States, 50023
- UI Health Care Mission Cancer and Blood - Ankeny Clinic
-
Boone, Iowa, United States, 50036
- McFarland Clinic - Boone
-
Carroll, Iowa, United States, 51401
- Saint Anthony Regional Hospital
-
Clive, Iowa, United States, 50325
- Mercy Cancer Center-West Lakes
-
Clive, Iowa, United States, 50325
- UI Health Care Mission Cancer and Blood - West Des Moines Clinic
-
Council Bluffs, Iowa, United States, 51503
- Alegent Health Mercy Hospital
-
Council Bluffs, Iowa, United States, 51503
- Heartland Oncology and Hematology LLP
-
Council Bluffs, Iowa, United States, 51503
- Methodist Jennie Edmundson Hospital
-
Council Bluffs, Iowa, United States, 51503
- Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ
-
Creston, Iowa, United States, 50801
- Greater Regional Medical Center
-
Des Moines, Iowa, United States, 50309
- Iowa Methodist Medical Center
-
Des Moines, Iowa, United States, 50314
- Mercy Medical Center - Des Moines
-
Des Moines, Iowa, United States, 50314
- Broadlawns Medical Center
-
Des Moines, Iowa, United States, 50316
- Iowa Lutheran Hospital
-
Des Moines, Iowa, United States, 50309
- UI Health Care Mission Cancer and Blood - Des Moines Clinic
-
Des Moines, Iowa, United States, 50314
- UI Health Care Mission Cancer and Blood - Laurel Clinic
-
Fort Dodge, Iowa, United States, 50501
- McFarland Clinic - Trinity Cancer Center
-
Fort Dodge, Iowa, United States, 50501
- UI Healthcare Mission Cancer and Blood - Fort Dodge
-
Iowa City, Iowa, United States, 52242
- University of Iowa/Holden Comprehensive Cancer Center
-
Jefferson, Iowa, United States, 50129
- McFarland Clinic - Jefferson
-
Marshalltown, Iowa, United States, 50158
- McFarland Clinic - Marshalltown
-
West Des Moines, Iowa, United States, 50266-7700
- Methodist West Hospital
-
West Des Moines, Iowa, United States, 50266
- Mercy Medical Center-West Lakes
-
-
Kansas
-
Coffeyville, Kansas, United States, 67337
- Coffeyville Regional Medical Center
-
Garden City, Kansas, United States, 67846
- Central Care Cancer Center - Garden City
-
Great Bend, Kansas, United States, 67530
- Central Care Cancer Center - Great Bend
-
Hays, Kansas, United States, 67601
- HaysMed
-
Kansas City, Kansas, United States, 66160
- University of Kansas Cancer Center
-
Kansas City, Kansas, United States, 66112
- University of Kansas Cancer Center-West
-
Lawrence, Kansas, United States, 66044
- Lawrence Memorial Hospital
-
Olathe, Kansas, United States, 66061
- The University of Kansas Cancer Center - Olathe
-
Overland Park, Kansas, United States, 66210
- University of Kansas Cancer Center-Overland Park
-
Overland Park, Kansas, United States, 66211
- University of Kansas Hospital-Indian Creek Campus
-
Pittsburg, Kansas, United States, 66762
- Freeman Physician Group of Pittsburg
-
Pittsburg, Kansas, United States, 66762
- Mercy Hospital Pittsburg
-
Salina, Kansas, United States, 67401
- Salina Regional Health Center
-
Topeka, Kansas, United States, 66606
- University of Kansas Health System Saint Francis Campus
-
Westwood, Kansas, United States, 66205
- University of Kansas Hospital-Westwood Cancer Center
-
-
Kentucky
-
Bardstown, Kentucky, United States, 40004
- Flaget Memorial Hospital
-
Corbin, Kentucky, United States, 40701
- Baptist Health Corbin
-
Corbin, Kentucky, United States, 40701
- Commonwealth Cancer Center-Corbin
-
Lexington, Kentucky, United States, 40504
- Saint Joseph Radiation Oncology Resource Center
-
Lexington, Kentucky, United States, 40509
- Saint Joseph Hospital East
-
Lexington, Kentucky, United States, 40503
- Baptist Health Lexington
-
Lexington, Kentucky, United States, 40504
- Saint Joseph Hospital
-
London, Kentucky, United States, 40741
- Saint Joseph London
-
Louisville, Kentucky, United States, 40202
- Jewish Hospital
-
Louisville, Kentucky, United States, 40245
- UofL Health Medical Center Northeast
-
Louisville, Kentucky, United States, 40207
- Baptist Health Louisville
-
Louisville, Kentucky, United States, 40215
- Saints Mary and Elizabeth Hospital
-
Madisonville, Kentucky, United States, 42431
- Baptist Health Madisonville/Merle Mahr Cancer Center
-
Mount Sterling, Kentucky, United States, 40353
- Saint Joseph Mount Sterling
-
Paducah, Kentucky, United States, 42003
- Baptist Health Paducah
-
Paducah, Kentucky, United States, 42003
- Mercy Health - Paducah Cancer Center
-
Shepherdsville, Kentucky, United States, 40165
- Jewish Hospital Medical Center South
-
-
Louisiana
-
Marrero, Louisiana, United States, 70072
- West Jefferson Medical Center
-
Metairie, Louisiana, United States, 70006
- East Jefferson General Hospital
-
Metairie, Louisiana, United States, 70006
- LSU Healthcare Network / Metairie Multi-Specialty Clinic
-
New Orleans, Louisiana, United States, 70112
- University Medical Center New Orleans
-
New Orleans, Louisiana, United States, 70112
- Louisiana State University Health Science Center
-
-
Maine
-
Augusta, Maine, United States, 04330
- Harold Alfond Center for Cancer Care
-
Bangor, Maine, United States, 04401
- Eastern Maine Medical Center
-
Belfast, Maine, United States, 04915
- MaineHealth Waldo Hospital
-
Biddeford, Maine, United States, 04005
- MaineHealth Maine Medical Center - Biddeford
-
Brewer, Maine, United States, 04412
- Lafayette Family Cancer Center-EMMC
-
Rockport, Maine, United States, 04856
- Penobscot Bay Medical Center
-
Sanford, Maine, United States, 04073
- MaineHealth Cancer Care and IV Therapy - Sanford
-
Scarborough, Maine, United States, 04074
- MaineHealth Maine Medical Center- Scarborough
-
-
Maryland
-
Baltimore, Maryland, United States, 21287
- Johns Hopkins University/Sidney Kimmel Cancer Center
-
Baltimore, Maryland, United States, 21204
- Greater Baltimore Medical Center
-
Baltimore, Maryland, United States, 21201
- University of Maryland/Greenebaum Cancer Center
-
Elkton, Maryland, United States, 21921
- Christiana Care - Union Hospital
-
-
Massachusetts
-
Boston, Massachusetts, United States, 02215
- Dana-Farber Cancer Institute
-
Boston, Massachusetts, United States, 02111
- Tufts Medical Center
-
Burlington, Massachusetts, United States, 01805
- Lahey Hospital and Medical Center
-
Springfield, Massachusetts, United States, 01199
- Baystate Medical Center
-
Worcester, Massachusetts, United States, 01605
- UMass Memorial Medical Center - Memorial Division
-
-
Michigan
-
Alma, Michigan, United States, 48801
- MyMichigan Medical Center Gratiot
-
Alpena, Michigan, United States, 49707
- MyMichigan Medical Center Alpena
-
Ann Arbor, Michigan, United States, 48109
- University of Michigan Rogel Cancer Center
-
Ann Arbor, Michigan, United States, 48106
- Trinity Health Saint Joseph Mercy Hospital Ann Arbor
-
Battle Creek, Michigan, United States, 49017
- Bronson Battle Creek
-
Brighton, Michigan, United States, 48114
- Trinity Health IHA Medical Group Hematology Oncology - Brighton
-
Brighton, Michigan, United States, 48116
- University of Michigan - Brighton Center for Specialty Care
-
Brighton, Michigan, United States, 48114
- Trinity Health Medical Center - Brighton
-
Canton, Michigan, United States, 48188
- Trinity Health IHA Medical Group Hematology Oncology - Canton
-
Canton, Michigan, United States, 48188
- Trinity Health Medical Center - Canton
-
Caro, Michigan, United States, 48723
- Caro Cancer Center
-
Chelsea, Michigan, United States, 48118
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
-
Chelsea, Michigan, United States, 48118
- Chelsea Hospital
-
Clarkston, Michigan, United States, 48346
- Hematology Oncology Consultants-Clarkston
-
Clarkston, Michigan, United States, 48346
- Newland Medical Associates-Clarkston
-
Dearborn, Michigan, United States, 48124
- Corewell Health Dearborn Hospital
-
Detroit, Michigan, United States, 48201
- Wayne State University/Karmanos Cancer Institute
-
Detroit, Michigan, United States, 48236
- Henry Ford Health Saint John Hospital
-
East China Township, Michigan, United States, 48054
- Henry Ford River District Hospital
-
Farmington Hills, Michigan, United States, 48334
- Weisberg Cancer Treatment Center
-
Farmington Hills, Michigan, United States, 48336
- Corewell Health Farmington Hills Hospital
-
Flint, Michigan, United States, 48503
- Hurley Medical Center
-
Flint, Michigan, United States, 48503
- Genesee Hematology Oncology PC
-
Flint, Michigan, United States, 48503
- Genesys Hurley Cancer Institute
-
Flint, Michigan, United States, 48503
- Cancer Hematology Centers - Flint
-
Gladwin, Michigan, United States, 48624
- MyMichigan Medical Center Gladwin
-
Grand Rapids, Michigan, United States, 49503
- Trinity Health Grand Rapids Hospital
-
Grand Rapids, Michigan, United States, 49503
- Corewell Health Grand Rapids Hospitals - Butterworth Hospital
-
Grand Rapids, Michigan, United States, 49503
- Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital
-
Grosse Pointe Woods, Michigan, United States, 48236
- Henry Ford Saint John Hospital - Academic
-
Grosse Pointe Woods, Michigan, United States, 48236
- Henry Ford Saint John Hospital - Breast
-
Grosse Pointe Woods, Michigan, United States, 48236
- Henry Ford Saint John Hospital - Van Elslander
-
Kalamazoo, Michigan, United States, 49007
- West Michigan Cancer Center
-
Kalamazoo, Michigan, United States, 49007
- Bronson Methodist Hospital
-
Kalamazoo, Michigan, United States, 49009
- Beacon Kalamazoo Cancer Center
-
Kalamazoo, Michigan, United States, 49048
- Beacon Kalamazoo
-
Lansing, Michigan, United States, 48912
- University of Michigan Health - Sparrow Lansing
-
Livonia, Michigan, United States, 48154
- Trinity Health Saint Mary Mercy Livonia Hospital
-
Livonia, Michigan, United States, 48154
- Hope Cancer Clinic
-
Macomb, Michigan, United States, 48044
- Henry Ford Warren Hospital - Breast Macomb
-
Macomb, Michigan, United States, 48044
- Henry Ford Saint John Hospital - Macomb Medical
-
Marlette, Michigan, United States, 48453
- Saint Mary's Oncology/Hematology Associates of Marlette
-
Midland, Michigan, United States, 48670
- MyMichigan Medical Center Midland
-
Mount Pleasant, Michigan, United States, 48858
- MyMichigan Medical Center Mount Pleasant
-
Muskegon, Michigan, United States, 49444
- Trinity Health Muskegon Hospital
-
Niles, Michigan, United States, 49120
- Corewell Health Lakeland Hospitals - Niles Hospital
-
Norton Shores, Michigan, United States, 49444
- Cancer and Hematology Centers of Western Michigan - Norton Shores
-
Pontiac, Michigan, United States, 48341
- Hope Cancer Center
-
Pontiac, Michigan, United States, 48341
- Newland Medical Associates-Pontiac
-
Pontiac, Michigan, United States, 48341
- Trinity Health Saint Joseph Mercy Oakland Hospital
-
Pontiac, Michigan, United States, 48341
- Michigan Healthcare Professionals Pontiac
-
Reed City, Michigan, United States, 49677
- Corewell Health Reed City Hospital
-
Rochester Hills, Michigan, United States, 48309
- Henry Ford Rochester Hospital
-
Royal Oak, Michigan, United States, 48073
- Cancer Care Associates PC
-
Royal Oak, Michigan, United States, 48073
- Comprehensive Medical Center PLLC
-
Royal Oak, Michigan, United States, 48073
- Oakland Medical Group
-
Royal Oak, Michigan, United States, 48067
- Oakland Colon Rectal Associates
-
Royal Oak, Michigan, United States, 48073
- Corewell Health William Beaumont University Hospital
-
Saginaw, Michigan, United States, 48604
- Oncology Hematology Associates of Saginaw Valley PC
-
Saginaw, Michigan, United States, 48601
- MyMichigan Medical Center Saginaw
-
Saint Joseph, Michigan, United States, 49085
- Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
-
Saint Joseph, Michigan, United States, 49085
- Corewell Health Lakeland Hospitals - Saint Joseph Hospital
-
Sterling Heights, Michigan, United States, 48312
- Bhadresh Nayak MD PC-Sterling Heights
-
Sterling Heights, Michigan, United States, 48312
- Premier Hematology Oncology Care
-
Tawas City, Michigan, United States, 48764
- MyMichigan Medical Center Tawas
-
Traverse City, Michigan, United States, 49684
- Munson Medical Center
-
Troy, Michigan, United States, 48084
- Michigan Institute of Urology-Town Center
-
Troy, Michigan, United States, 48098
- Hematology Oncology Consultants PC-Troy
-
Troy, Michigan, United States, 48085
- Corewell Health Beaumont Troy Hospital
-
Warren, Michigan, United States, 48088
- Advanced Breast Care Center PLLC
-
Warren, Michigan, United States, 48093
- Macomb Hematology Oncology PC
-
Warren, Michigan, United States, 48093
- Henry Ford Madison Heights Hospital - Breast
-
Warren, Michigan, United States, 48093
- Henry Ford Health Warren Hospital
-
Warren, Michigan, United States, 48093
- Henry Ford Warren Hospital - GLCMS
-
West Branch, Michigan, United States, 48661
- Saint Mary's Oncology/Hematology Associates of West Branch
-
Wyoming, Michigan, United States, 49519
- University of Michigan Health - West
-
Ypsilanti, Michigan, United States, 48197
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
-
Ypsilanti, Michigan, United States, 48106
- Huron Gastroenterology PC
-
-
Minnesota
-
Albert Lea, Minnesota, United States, 56007
- Mayo Clinic Health System in Albert Lea
-
Bemidji, Minnesota, United States, 56601
- Sanford Joe Lueken Cancer Center
-
Burnsville, Minnesota, United States, 55337
- Fairview Ridges Hospital
-
Burnsville, Minnesota, United States, 55337
- Minnesota Oncology - Burnsville
-
Cambridge, Minnesota, United States, 55008
- Cambridge Medical Center
-
Coon Rapids, Minnesota, United States, 55433
- Mercy Hospital
-
Edina, Minnesota, United States, 55435
- Fairview Southdale Hospital
-
Fridley, Minnesota, United States, 55432
- Unity Hospital
-
Maple Grove, Minnesota, United States, 55369
- Fairview Clinics and Surgery Center Maple Grove
-
Maplewood, Minnesota, United States, 55109
- Saint John's Hospital - Healtheast
-
Maplewood, Minnesota, United States, 55109
- Minnesota Oncology Hematology PA-Maplewood
-
Minneapolis, Minnesota, United States, 55415
- Hennepin County Medical Center
-
Minneapolis, Minnesota, United States, 55407
- Abbott-Northwestern Hospital
-
Minneapolis, Minnesota, United States, 55454
- Health Partners Inc
-
Minneapolis, Minnesota, United States, 55455
- University of Minnesota/Masonic Cancer Center
-
Monticello, Minnesota, United States, 55362
- Monticello Cancer Center
-
New Ulm, Minnesota, United States, 56073
- New Ulm Medical Center
-
Princeton, Minnesota, United States, 55371
- Fairview Northland Medical Center
-
Robbinsdale, Minnesota, United States, 55422
- North Memorial Medical Health Center
-
Rochester, Minnesota, United States, 55905
- Mayo Clinic in Rochester
-
Saint Louis Park, Minnesota, United States, 55416
- Park Nicollet Clinic - Saint Louis Park
-
Saint Paul, Minnesota, United States, 55101
- Regions Hospital
-
Saint Paul, Minnesota, United States, 55102
- United Hospital
-
Shakopee, Minnesota, United States, 55379
- Saint Francis Regional Medical Center
-
Stillwater, Minnesota, United States, 55082
- Lakeview Hospital
-
Waconia, Minnesota, United States, 55387
- Ridgeview Medical Center
-
Willmar, Minnesota, United States, 56201
- Rice Memorial Hospital
-
Woodbury, Minnesota, United States, 55125
- Minnesota Oncology Hematology PA-Woodbury
-
Wyoming, Minnesota, United States, 55092
- Fairview Lakes Medical Center
-
-
Mississippi
-
Gulfport, Mississippi, United States, 39502
- Gulfport Memorial Hospital
-
Jackson, Mississippi, United States, 39202
- Mississippi Baptist Medical Center
-
-
Missouri
-
Ballwin, Missouri, United States, 63011
- Mercy Oncology and Hematology - Clayton-Clarkson
-
Bolivar, Missouri, United States, 65613
- Central Care Cancer Center - Bolivar
-
Bonne Terre, Missouri, United States, 63628
- Parkland Health Center-Bonne Terre
-
Branson, Missouri, United States, 65616
- Cox Cancer Center Branson
-
Cape Girardeau, Missouri, United States, 63703
- Saint Francis Medical Center
-
Cape Girardeau, Missouri, United States, 63703
- Mercy Cancer Center - Cape Girardeau
-
Farmington, Missouri, United States, 63640
- Parkland Health Center - Farmington
-
Jefferson City, Missouri, United States, 65109
- MU Health Care Goldschmidt Cancer Center
-
Joplin, Missouri, United States, 64804
- Freeman Health System
-
Joplin, Missouri, United States, 64804
- Mercy Hospital Joplin
-
Kansas City, Missouri, United States, 64154
- University of Kansas Cancer Center - North
-
Kansas City, Missouri, United States, 64108
- University Health Truman Medical Center
-
Lee's Summit, Missouri, United States, 64064
- University of Kansas Cancer Center - Lee's Summit
-
North Kansas City, Missouri, United States, 64116
- University of Kansas Cancer Center at North Kansas City Hospital
-
Osage Beach, Missouri, United States, 65065
- Lake Regional Hospital
-
Rolla, Missouri, United States, 65401
- Mercy Clinic-Rolla-Cancer and Hematology
-
Rolla, Missouri, United States, 65401
- Phelps Health Delbert Day Cancer Institute
-
Saint Joseph, Missouri, United States, 64506
- Heartland Regional Medical Center
-
Sainte Genevieve, Missouri, United States, 63670
- Sainte Genevieve County Memorial Hospital
-
Springfield, Missouri, United States, 65807
- CoxHealth South Hospital
-
Springfield, Missouri, United States, 65804
- Mercy Hospital Springfield
-
St Louis, Missouri, United States, 63110
- Washington University School of Medicine
-
St Louis, Missouri, United States, 63131
- Missouri Baptist Medical Center
-
St Louis, Missouri, United States, 63109
- Mercy Infusion Center - Chippewa
-
St Louis, Missouri, United States, 63141
- Mercy Hospital Saint Louis
-
St Louis, Missouri, United States, 63128
- Mercy Hospital South
-
Sullivan, Missouri, United States, 63080
- Missouri Baptist Sullivan Hospital
-
Sunset Hills, Missouri, United States, 63127
- BJC Outpatient Center at Sunset Hills
-
Washington, Missouri, United States, 63090
- Mercy Hospital Washington
-
-
Montana
-
Anaconda, Montana, United States, 59711
- Community Hospital of Anaconda
-
Billings, Montana, United States, 59101
- Billings Clinic Cancer Center
-
Billings, Montana, United States, 59101
- Saint Vincent Healthcare
-
Billings, Montana, United States, 59102
- Saint Vincent Frontier Cancer Center
-
Billings, Montana, United States, 59106
- Intermountain Health West End Clinic
-
Bozeman, Montana, United States, 59715
- Bozeman Health Deaconess Hospital
-
Butte, Montana, United States, 59701
- Saint James Community Hospital and Cancer Treatment Center
-
Great Falls, Montana, United States, 59405
- Great Falls Clinic
-
Great Falls, Montana, United States, 59405
- Benefis Sletten Cancer Institute
-
Havre, Montana, United States, 59501
- Hi-Line Sletten Cancer Center
-
Kalispell, Montana, United States, 59901
- Logan Health Medical Center
-
Missoula, Montana, United States, 59802
- Saint Patrick Hospital - Community Hospital
-
Missoula, Montana, United States, 59804
- Community Medical Center
-
-
Nebraska
-
Grand Island, Nebraska, United States, 68803
- CHI Health Saint Francis
-
Grand Island, Nebraska, United States, 68803
- Nebraska Cancer Specialists/Oncology Hematology West PC
-
Kearney, Nebraska, United States, 68847
- CHI Health Good Samaritan
-
Lincoln, Nebraska, United States, 68510
- Saint Elizabeth Regional Medical Center
-
Lincoln, Nebraska, United States, 68516
- Cancer Partners of Nebraska
-
Omaha, Nebraska, United States, 68114
- Nebraska Methodist Hospital
-
Omaha, Nebraska, United States, 68198
- University of Nebraska Medical Center
-
Omaha, Nebraska, United States, 68124
- Alegent Health Bergan Mercy Medical Center
-
Omaha, Nebraska, United States, 68118
- Nebraska Medicine-Village Pointe
-
Omaha, Nebraska, United States, 68122
- Alegent Health Immanuel Medical Center
-
Omaha, Nebraska, United States, 68130
- Alegent Health Lakeside Hospital
-
Omaha, Nebraska, United States, 68131
- Creighton University Medical Center
-
Omaha, Nebraska, United States, 68114
- Oncology Associates PC
-
Omaha, Nebraska, United States, 68114
- Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
-
Papillion, Nebraska, United States, 68046
- Midlands Community Hospital
-
-
Nevada
-
Carson City, Nevada, United States, 89703
- Carson Tahoe Regional Medical Center
-
Henderson, Nevada, United States, 89052
- Comprehensive Cancer Centers of Nevada - Henderson
-
Henderson, Nevada, United States, 89052
- OptumCare Cancer Care at Seven Hills
-
Henderson, Nevada, United States, 89052
- Cancer and Blood Specialists-Henderson
-
Henderson, Nevada, United States, 89074
- Comprehensive Cancer Centers of Nevada-Southeast Henderson
-
Henderson, Nevada, United States, 89052
- Comprehensive Cancer Centers of Nevada-Horizon Ridge
-
Henderson, Nevada, United States, 89074
- Las Vegas Urology - Green Valley
-
Henderson, Nevada, United States, 89074
- Las Vegas Urology - Pebble
-
Henderson, Nevada, United States, 89074
- Urology Specialists of Nevada - Green Valley
-
Henderson, Nevada, United States, 89074
- Oncology Las Vegas - Henderson
-
Las Vegas, Nevada, United States, 89144
- Summerlin Hospital Medical Center
-
Las Vegas, Nevada, United States, 89109
- Sunrise Hospital and Medical Center
-
Las Vegas, Nevada, United States, 89102
- OptumCare Cancer Care at Charleston
-
Las Vegas, Nevada, United States, 89106
- Radiation Oncology Centers of Nevada Central
-
Las Vegas, Nevada, United States, 89119
- Radiation Oncology Centers of Nevada Southeast
-
Las Vegas, Nevada, United States, 89128
- Comprehensive Cancer Centers of Nevada - Northwest
-
Las Vegas, Nevada, United States, 89128
- OptumCare Cancer Care at MountainView
-
Las Vegas, Nevada, United States, 89135
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation
-
Las Vegas, Nevada, United States, 89144
- Comprehensive Cancer Centers of Nevada - Town Center
-
Las Vegas, Nevada, United States, 89144
- Comprehensive Cancer Centers of Nevada-Summerlin
-
Las Vegas, Nevada, United States, 89148
- Comprehensive Cancer Centers of Nevada
-
Las Vegas, Nevada, United States, 89148
- OptumCare Cancer Care at Fort Apache
-
Las Vegas, Nevada, United States, 89169
- Comprehensive Cancer Centers of Nevada - Central Valley
-
Las Vegas, Nevada, United States, 89106
- Women's Cancer Center of Nevada
-
Las Vegas, Nevada, United States, 89102
- University Medical Center of Southern Nevada
-
Las Vegas, Nevada, United States, 89128
- Ann M Wierman MD LTD
-
Las Vegas, Nevada, United States, 89074
- Las Vegas Urology - Pecos
-
Las Vegas, Nevada, United States, 89103
- Hope Cancer Care of Nevada
-
Las Vegas, Nevada, United States, 89106
- Urology Specialists of Nevada - Central
-
Las Vegas, Nevada, United States, 89113
- Las Vegas Prostate Cancer Center
-
Las Vegas, Nevada, United States, 89113
- Las Vegas Urology - Sunset
-
Las Vegas, Nevada, United States, 89128
- Las Vegas Urology - Cathedral Rock
-
Las Vegas, Nevada, United States, 89128
- Las Vegas Urology - Smoke Ranch
-
Las Vegas, Nevada, United States, 89128
- Urology Specialists of Nevada - Northwest
-
Las Vegas, Nevada, United States, 89169
- University Cancer Center
-
Las Vegas, Nevada, United States, 89113
- Urology Specialists of Nevada - Southwest
-
Las Vegas, Nevada, United States, 89128
- Oncology Las Vegas - Tenaya
-
Pahrump, Nevada, United States, 89048
- Hope Cancer Care of Nevada-Pahrump
-
Reno, Nevada, United States, 89502
- Renown Regional Medical Center
-
Reno, Nevada, United States, 89503
- Saint Mary's Regional Medical Center
-
Reno, Nevada, United States, 89509
- Radiation Oncology Associates
-
-
New Jersey
-
Basking Ridge, New Jersey, United States, 07920
- Memorial Sloan Kettering Basking Ridge
-
Camden, New Jersey, United States, 08103
- Cooper Hospital University Medical Center
-
Hackensack, New Jersey, United States, 07601
- Hackensack University Medical Center
-
Middletown, New Jersey, United States, 07748
- Memorial Sloan Kettering Monmouth
-
Montvale, New Jersey, United States, 07645
- Memorial Sloan Kettering Bergen
-
Moorestown, New Jersey, United States, 08057
- Virtua Samson Cancer Center
-
Voorhees Township, New Jersey, United States, 08043
- MD Anderson Cancer Center at Cooper-Voorhees
-
Voorhees Township, New Jersey, United States, 08043
- Virtua Voorhees
-
-
New Mexico
-
Albuquerque, New Mexico, United States, 87106
- University of New Mexico Cancer Center
-
-
New York
-
Albany, New York, United States, 12208
- Women's Cancer Care Associates LLC
-
Brooklyn, New York, United States, 11215
- New York-Presbyterian/Brooklyn Methodist Hospital
-
Buffalo, New York, United States, 14263
- Roswell Park Cancer Institute
-
Commack, New York, United States, 11725
- Memorial Sloan Kettering Commack
-
Flushing, New York, United States, 11355
- The New York Hospital Medical Center of Queens
-
Harrison, New York, United States, 10604
- Memorial Sloan Kettering Westchester
-
New York, New York, United States, 10065
- Memorial Sloan Kettering Cancer Center
-
New York, New York, United States, 10029
- Mount Sinai Hospital
-
New York, New York, United States, 10032
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
-
New York, New York, United States, 10065
- NYP/Weill Cornell Medical Center
-
New York, New York, United States, 10011
- Mount Sinai Chelsea
-
Rochester, New York, United States, 14642
- University of Rochester
-
Rochester, New York, United States, 14620
- Highland Hospital
-
Stony Brook, New York, United States, 11794
- Stony Brook University Medical Center
-
Syracuse, New York, United States, 13210
- State University of New York Upstate Medical University
-
Uniondale, New York, United States, 11553
- Memorial Sloan Kettering Nassau
-
Valhalla, New York, United States, 10595
- Westchester Medical Center
-
-
North Carolina
-
Cary, North Carolina, United States, 27518
- Duke Cancer Center Cary
-
Chapel Hill, North Carolina, United States, 27599
- UNC Lineberger Comprehensive Cancer Center
-
Charlotte, North Carolina, United States, 28203
- Carolinas Medical Center/Levine Cancer Institute
-
Clinton, North Carolina, United States, 28328
- Southeastern Medical Oncology Center-Clinton
-
Concord, North Carolina, United States, 28025
- Atrium Health Cabarrus/LCI-Concord
-
Durham, North Carolina, United States, 27710
- Duke University Medical Center
-
Gastonia, North Carolina, United States, 28054
- Levine Cancer Institute-Gaston
-
Goldsboro, North Carolina, United States, 27534
- Southeastern Medical Oncology Center-Goldsboro
-
Greenville, North Carolina, United States, 27834
- ECU Health Medical Center
-
Hendersonville, North Carolina, United States, 28791
- Margaret R Pardee Memorial Hospital
-
High Point, North Carolina, United States, 27262
- Hayworth Cancer Center
-
Jacksonville, North Carolina, United States, 28546
- Southeastern Medical Oncology Center-Jacksonville
-
Raleigh, North Carolina, United States, 27607
- Duke Women's Cancer Care Raleigh
-
Raleigh, North Carolina, United States, 27609
- Duke Cancer Center Raleigh
-
Wilmington, North Carolina, United States, 28401
- Novant Health New Hanover Regional Medical Center
-
Winston-Salem, North Carolina, United States, 27157
- Wake Forest University Health Sciences
-
-
North Dakota
-
Bismarck, North Dakota, United States, 58501
- Sanford Bismarck Medical Center
-
Fargo, North Dakota, United States, 58122
- Sanford Roger Maris Cancer Center
-
Fargo, North Dakota, United States, 58122
- Sanford Broadway Medical Center
-
-
Ohio
-
Athens, Ohio, United States, 45701
- OhioHealth O'Bleness Hospital
-
Beavercreek, Ohio, United States, 45431
- Indu and Raj Soin Medical Center
-
Belpre, Ohio, United States, 45714
- Strecker Cancer Center-Belpre
-
Boardman, Ohio, United States, 44512
- Saint Elizabeth Boardman Hospital
-
Centerville, Ohio, United States, 45459
- Miami Valley Hospital South
-
Centerville, Ohio, United States, 45459
- Dayton Physicians LLC-Miami Valley South
-
Chillicothe, Ohio, United States, 45601
- Adena Regional Medical Center
-
Cincinnati, Ohio, United States, 45220
- Good Samaritan Hospital - Cincinnati
-
Cincinnati, Ohio, United States, 45242
- Bethesda North Hospital
-
Cincinnati, Ohio, United States, 45236
- Oncology Hematology Care Inc-Kenwood
-
Cincinnati, Ohio, United States, 45247
- TriHealth Cancer Institute-Westside
-
Cincinnati, Ohio, United States, 45255
- TriHealth Cancer Institute-Anderson
-
Cleveland, Ohio, United States, 44109
- MetroHealth Medical Center
-
Cleveland, Ohio, United States, 44195
- Cleveland Clinic Foundation
-
Cleveland, Ohio, United States, 44111
- Cleveland Clinic Cancer Center/Fairview Hospital
-
Columbus, Ohio, United States, 43214
- Riverside Methodist Hospital
-
Columbus, Ohio, United States, 43210
- Ohio State University Comprehensive Cancer Center
-
Columbus, Ohio, United States, 43219
- The Mark H Zangmeister Center
-
Columbus, Ohio, United States, 43214
- Columbus Oncology and Hematology Associates Inc
-
Columbus, Ohio, United States, 43228
- Doctors Hospital
-
Columbus, Ohio, United States, 43213
- Mount Carmel East Hospital
-
Columbus, Ohio, United States, 43215
- Grant Medical Center
-
Columbus, Ohio, United States, 43222
- Mount Carmel Health Center West
-
Dayton, Ohio, United States, 45406
- Good Samaritan Hospital - Dayton
-
Dayton, Ohio, United States, 45409
- Miami Valley Hospital
-
Dayton, Ohio, United States, 45415
- Miami Valley Hospital North
-
Dayton, Ohio, United States, 45415
- Dayton Physician LLC - Englewood
-
Delaware, Ohio, United States, 43015
- Delaware Health Center-Grady Cancer Center
-
Delaware, Ohio, United States, 43015
- Grady Memorial Hospital
-
Dublin, Ohio, United States, 43016
- Dublin Methodist Hospital
-
Dublin, Ohio, United States, 43016
- Columbus Oncology and Hematology Associates
-
Findlay, Ohio, United States, 45840
- Blanchard Valley Hospital
-
Findlay, Ohio, United States, 45840
- Armes Family Cancer Center
-
Findlay, Ohio, United States, 45840
- Orion Cancer Care
-
Franklin, Ohio, United States, 45005-1066
- Atrium Medical Center-Middletown Regional Hospital
-
Franklin, Ohio, United States, 45005
- Dayton Physicians LLC-Atrium
-
Gahanna, Ohio, United States, 43230
- Central Ohio Breast and Endocrine Surgery
-
Greenville, Ohio, United States, 45331
- Wayne Hospital
-
Greenville, Ohio, United States, 45331
- Dayton Physicians LLC-Wayne
-
Greenville, Ohio, United States, 45331
- Miami Valley Cancer Care and Infusion
-
Grove City, Ohio, United States, 43123
- Mount Carmel Grove City Hospital
-
Grove City, Ohio, United States, 43123
- Zangmeister Center Grove City
-
Kettering, Ohio, United States, 45429
- Kettering Medical Center
-
Kettering, Ohio, United States, 45409
- Greater Dayton Cancer Center
-
Kettering, Ohio, United States, 45420
- First Dayton Cancer Care
-
Lancaster, Ohio, United States, 43130
- Fairfield Medical Center
-
Lima, Ohio, United States, 45801
- Saint Rita's Medical Center
-
Mansfield, Ohio, United States, 44903
- OhioHealth Mansfield Hospital
-
Marietta, Ohio, United States, 45750
- Marietta Memorial Hospital
-
Marion, Ohio, United States, 43302
- OhioHealth Marion General Hospital
-
Marysville, Ohio, United States, 43040
- Memorial Hospital
-
Mayfield Heights, Ohio, United States, 44124
- Hillcrest Hospital Cancer Center
-
Mount Vernon, Ohio, United States, 43050
- Knox Community Hospital
-
New Albany, Ohio, United States, 43054
- Mount Carmel New Albany Surgical Hospital
-
Newark, Ohio, United States, 43055
- Licking Memorial Hospital
-
Newark, Ohio, United States, 43055
- Newark Radiation Oncology
-
Perrysburg, Ohio, United States, 43551
- Mercy Health - Perrysburg Hospital
-
Pickerington, Ohio, United States, 43147
- OhioHealth Pickerington Methodist Hospital
-
Portsmouth, Ohio, United States, 45662
- Southern Ohio Medical Center
-
Springfield, Ohio, United States, 45504
- Springfield Regional Cancer Center
-
Springfield, Ohio, United States, 45504
- Springfield Regional Medical Center
-
Steubenville, Ohio, United States, 43952
- Trinity's Tony Teramana Cancer Center
-
Sylvania, Ohio, United States, 43560
- ProMedica Flower Hospital
-
Toledo, Ohio, United States, 43606
- ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
-
Toledo, Ohio, United States, 43623
- Mercy Health - Saint Anne Hospital
-
Toledo, Ohio, United States, 43608
- Mercy Health - Saint Vincent Hospital
-
Toledo, Ohio, United States, 43623
- Mercy Health Sylvania Radiation Oncology Center
-
Troy, Ohio, United States, 45373
- Upper Valley Medical Center
-
Troy, Ohio, United States, 45373
- Dayton Physicians LLC - Troy
-
Warren, Ohio, United States, 44484
- Saint Joseph Warren Hospital
-
Westerville, Ohio, United States, 43081
- Saint Ann's Hospital
-
Westerville, Ohio, United States, 43082
- OhioHealth Westerville Medical Campus/Westerville Cancer Center
-
Wilmington, Ohio, United States, 45177
- Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center
-
Youngstown, Ohio, United States, 44501
- Saint Elizabeth Youngstown Hospital
-
Zanesville, Ohio, United States, 43701
- Genesis Healthcare System Cancer Care Center
-
-
Oklahoma
-
Oklahoma City, Oklahoma, United States, 73104
- University of Oklahoma Health Sciences Center
-
Oklahoma City, Oklahoma, United States, 73120
- Mercy Hospital Oklahoma City
-
Tulsa, Oklahoma, United States, 74146
- Oklahoma Cancer Specialists and Research Institute-Tulsa
-
-
Oregon
-
Baker City, Oregon, United States, 97814
- Saint Alphonsus Cancer Care Center-Baker City
-
Bend, Oregon, United States, 97701
- Saint Charles Health System
-
Clackamas, Oregon, United States, 97015
- Clackamas Radiation Oncology Center
-
Clackamas, Oregon, United States, 97015
- Providence Cancer Institute Clackamas Clinic
-
Coos Bay, Oregon, United States, 97420
- Bay Area Hospital
-
Newberg, Oregon, United States, 97132
- Providence Newberg Medical Center
-
Ontario, Oregon, United States, 97914
- Saint Alphonsus Cancer Care Center-Ontario
-
Oregon City, Oregon, United States, 97045
- Providence Willamette Falls Medical Center
-
Portland, Oregon, United States, 97210
- Legacy Good Samaritan Hospital and Medical Center
-
Portland, Oregon, United States, 97213
- Providence Portland Medical Center
-
Portland, Oregon, United States, 97225
- Providence Saint Vincent Medical Center
-
Redmond, Oregon, United States, 97756
- Saint Charles Health System-Redmond
-
Tualatin, Oregon, United States, 97062
- Legacy Meridian Park Hospital
-
-
Pennsylvania
-
Allentown, Pennsylvania, United States, 18103
- Lehigh Valley Hospital-Cedar Crest
-
Allentown, Pennsylvania, United States, 18104
- Saint Luke's Cancer Center - Allentown
-
Altoona, Pennsylvania, United States, 16601
- UPMC Altoona
-
Bethel Park, Pennsylvania, United States, 15102
- UPMC Cancer Center-Bethel Park
-
Bethlehem, Pennsylvania, United States, 18017
- Lehigh Valley Hospital - Muhlenberg
-
Bethlehem, Pennsylvania, United States, 18015
- Saint Luke's University Hospital-Bethlehem Campus
-
Bryn Mawr, Pennsylvania, United States, 19010
- Bryn Mawr Hospital
-
Chadds Ford, Pennsylvania, United States, 19317
- Christiana Care Health System-Concord Health Center
-
Collegeville, Pennsylvania, United States, 19426
- Main Line Health Center-Collegeville
-
Cranberry Township, Pennsylvania, United States, 16066
- UPMC Hillman Cancer Center - Passavant - Cranberry
-
Danville, Pennsylvania, United States, 17822
- Geisinger Medical Center
-
East Stroudsburg, Pennsylvania, United States, 18301
- Pocono Medical Center
-
Easton, Pennsylvania, United States, 18045
- Saint Luke's Hospital-Anderson Campus
-
Erie, Pennsylvania, United States, 16505
- UPMC Hillman Cancer Center Erie
-
Erie, Pennsylvania, United States, 16544
- Saint Vincent Hospital
-
Exton, Pennsylvania, United States, 19341
- Main Line Health Center-Exton
-
Greensburg, Pennsylvania, United States, 15601
- UPMC Cancer Centers - Arnold Palmer Pavilion
-
Hazleton, Pennsylvania, United States, 18201
- Geisinger Medical Center-Cancer Center Hazleton
-
Hazleton, Pennsylvania, United States, 18201
- Lehigh Valley Hospital-Hazleton
-
Jefferson Hills, Pennsylvania, United States, 15025
- Jefferson Hospital
-
Lancaster, Pennsylvania, United States, 17601
- Lancaster General Ann B Barshinger Cancer Institute
-
Lewisburg, Pennsylvania, United States, 17837
- Geisinger Medical Oncology-Lewisburg
-
Lewistown, Pennsylvania, United States, 17044
- Lewistown Hospital
-
Media, Pennsylvania, United States, 19063
- Riddle Memorial Hospital
-
Monroeville, Pennsylvania, United States, 15146
- Forbes Hospital
-
Monroeville, Pennsylvania, United States, 15146
- UPMC Hillman Cancer Center - Monroeville
-
Paoli, Pennsylvania, United States, 19301
- Paoli Memorial Hospital
-
Philadelphia, Pennsylvania, United States, 19107
- Thomas Jefferson University Hospital
-
Philadelphia, Pennsylvania, United States, 19104
- University of Pennsylvania/Abramson Cancer Center
-
Pittsburgh, Pennsylvania, United States, 15212
- Allegheny General Hospital
-
Pittsburgh, Pennsylvania, United States, 15224
- West Penn Hospital
-
Pittsburgh, Pennsylvania, United States, 15213
- UPMC-Magee Womens Hospital
-
Pittsburgh, Pennsylvania, United States, 15232
- University of Pittsburgh Cancer Institute (UPCI)
-
Pittsburgh, Pennsylvania, United States, 15237
- UPMC-Passavant Hospital
-
Pittsburgh, Pennsylvania, United States, 15243
- UPMC-Saint Clair Hospital Cancer Center
-
Pottsville, Pennsylvania, United States, 17901
- Geisinger Cancer Services-Pottsville
-
Quakertown, Pennsylvania, United States, 18951
- Saint Luke's Hospital-Quakertown Campus
-
Quakertown, Pennsylvania, United States, 18951
- Saint Luke's Hospital - Upper Bucks Campus
-
Scranton, Pennsylvania, United States, 18510
- Community Medical Center
-
Selinsgrove, Pennsylvania, United States, 17870
- Geisinger Medical Oncology-Selinsgrove
-
Seneca, Pennsylvania, United States, 16346
- UPMC Cancer Center at UPMC Northwest
-
State College, Pennsylvania, United States, 16801
- Geisinger Medical Group
-
Stroudsburg, Pennsylvania, United States, 18360
- Saint Luke's Hospital - Monroe Campus
-
Uniontown, Pennsylvania, United States, 15401
- UPMC Cancer Center-Uniontown
-
Washington, Pennsylvania, United States, 15301
- UPMC Cancer Center-Washington
-
West Chester, Pennsylvania, United States, 19380
- Chester County Hospital
-
Wexford, Pennsylvania, United States, 15090
- Wexford Health and Wellness Pavilion
-
Wilkes-Barre, Pennsylvania, United States, 18711
- Geisinger Wyoming Valley/Henry Cancer Center
-
Willow Grove, Pennsylvania, United States, 19090
- Asplundh Cancer Pavilion
-
Wynnewood, Pennsylvania, United States, 19096
- Lankenau Medical Center
-
-
Rhode Island
-
Providence, Rhode Island, United States, 02905
- Women and Infants Hospital
-
-
South Carolina
-
Bluffton, South Carolina, United States, 29910
- Saint Joseph's/Candler - Bluffton Campus
-
Charleston, South Carolina, United States, 29425
- Medical University of South Carolina
-
Hilton Head Island, South Carolina, United States, 29926-3827
- South Carolina Cancer Specialists PC
-
-
South Dakota
-
Aberdeen, South Dakota, United States, 57401
- Avera Cancer Institute-Aberdeen
-
Pierre, South Dakota, United States, 57501
- Avera Cancer Institute at Pierre
-
Rapid City, South Dakota, United States, 57701
- Rapid City Regional Hospital
-
Sioux Falls, South Dakota, United States, 57105
- Avera Cancer Institute
-
Sioux Falls, South Dakota, United States, 57117-5134
- Sanford USD Medical Center - Sioux Falls
-
Sioux Falls, South Dakota, United States, 57104
- Sanford Cancer Center Oncology Clinic
-
Yankton, South Dakota, United States, 57078
- Avera Cancer Institute at Yankton
-
-
Tennessee
-
Bristol, Tennessee, United States, 37620
- Bristol Regional Medical Center
-
Johnson City, Tennessee, United States, 37604
- Regional Cancer Center at Johnson City Medical Center
-
Kingsport, Tennessee, United States, 37660
- Ballad Health Cancer Care - Kingsport
-
Kingsport, Tennessee, United States, 37660
- Wellmont Holston Valley Hospital and Medical Center
-
Memphis, Tennessee, United States, 38120
- Baptist Memorial Hospital and Cancer Center-Memphis
-
-
Texas
-
Bryan, Texas, United States, 77802
- Saint Joseph Regional Cancer Center
-
Dallas, Texas, United States, 75235
- Parkland Memorial Hospital
-
Dallas, Texas, United States, 75390
- UT Southwestern/Simmons Cancer Center-Dallas
-
Dallas, Texas, United States, 75237
- UT Southwestern Simmons Cancer Center - RedBird
-
Fort Worth, Texas, United States, 76104
- UT Southwestern/Simmons Cancer Center-Fort Worth
-
Fort Worth, Texas, United States, 76104
- Tarrant County Hospital District/JPS Health Network
-
Houston, Texas, United States, 77030
- M D Anderson Cancer Center
-
Houston, Texas, United States, 77026-1967
- Lyndon Baines Johnson General Hospital
-
Richardson, Texas, United States, 75080
- UT Southwestern Clinical Center at Richardson/Plano
-
-
Utah
-
Farmington, Utah, United States, 84025
- Farmington Health Center
-
Salt Lake City, Utah, United States, 84112
- Huntsman Cancer Institute/University of Utah
-
Salt Lake City, Utah, United States, 84106
- University of Utah Sugarhouse Health Center
-
South Jordan, Utah, United States, 84009
- South Jordan Health Center
-
-
Virginia
-
Bristol, Virginia, United States, 24201
- Ballad Health Cancer Care - Bristol
-
Charlottesville, Virginia, United States, 22908
- University of Virginia Cancer Center
-
Norton, Virginia, United States, 24273
- Ballad Health Cancer Care - Norton
-
Richmond, Virginia, United States, 23229
- Henrico Doctor's Hospital
-
-
Washington
-
Aberdeen, Washington, United States, 98520
- Providence Regional Cancer System-Aberdeen
-
Bellingham, Washington, United States, 98225
- PeaceHealth Saint Joseph Medical Center
-
Burien, Washington, United States, 98166
- Highline Medical Center-Main Campus
-
Centralia, Washington, United States, 98531
- Providence Regional Cancer System-Centralia
-
Edmonds, Washington, United States, 98026
- Swedish Cancer Institute-Edmonds
-
Enumclaw, Washington, United States, 98022
- Saint Elizabeth Hospital
-
Everett, Washington, United States, 98201
- Providence Regional Cancer Partnership
-
Federal Way, Washington, United States, 98003
- Saint Francis Hospital
-
Issaquah, Washington, United States, 98029
- Swedish Cancer Institute-Issaquah
-
Kennewick, Washington, United States, 99336
- Kadlec Clinic Hematology and Oncology
-
Lacey, Washington, United States, 98503
- Providence Regional Cancer System-Lacey
-
Lakewood, Washington, United States, 98499
- Saint Clare Hospital
-
Longview, Washington, United States, 98632
- PeaceHealth Saint John Medical Center
-
Mount Vernon, Washington, United States, 98274
- Skagit Regional Health Cancer Care Center
-
Port Townsend, Washington, United States, 98368
- Jefferson Healthcare
-
Poulsbo, Washington, United States, 98370
- Harrison HealthPartners Hematology and Oncology-Poulsbo
-
Renton, Washington, United States, 98055
- Valley Medical Center
-
Seattle, Washington, United States, 98107
- Swedish Medical Center-Ballard Campus
-
Seattle, Washington, United States, 98122
- Swedish Medical Center-First Hill
-
Seattle, Washington, United States, 98195
- University of Washington Medical Center - Montlake
-
Seattle, Washington, United States, 98104
- Pacific Gynecology Specialists
-
Seattle, Washington, United States, 98122-5711
- Swedish Medical Center-Cherry Hill
-
Seattle, Washington, United States, 98109
- Fred Hutchinson Cancer Center
-
Sedro-Woolley, Washington, United States, 98284
- PeaceHealth United General Medical Center
-
Shelton, Washington, United States, 98584
- Providence Regional Cancer System-Shelton
-
Silverdale, Washington, United States, 98383
- Saint Michael Cancer Center
-
Tacoma, Washington, United States, 98405
- Northwest Medical Specialties PLLC
-
Tacoma, Washington, United States, 98405
- Franciscan Research Center-Northwest Medical Plaza
-
Vancouver, Washington, United States, 98686
- Legacy Salmon Creek Hospital
-
Vancouver, Washington, United States, 98664
- PeaceHealth Southwest Medical Center
-
Walla Walla, Washington, United States, 99362
- Providence Saint Mary Regional Cancer Center
-
Yakima, Washington, United States, 98902
- North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
-
Yelm, Washington, United States, 98597
- Providence Regional Cancer System-Yelm
-
-
West Virginia
-
Bridgeport, West Virginia, United States, 26330
- United Hospital Center
-
Charleston, West Virginia, United States, 25304
- West Virginia University Charleston Division
-
Martinsburg, West Virginia, United States, 25401
- WVUH-Berkely Medical Center
-
Morgantown, West Virginia, United States, 26506
- West Virginia University Healthcare
-
Parkersburg, West Virginia, United States, 26101
- Camden Clark Medical Center
-
Princeton, West Virginia, United States, 24740
- Princeton Community Hospital
-
Wheeling, West Virginia, United States, 26003
- Wheeling Hospital/Schiffler Cancer Center
-
-
Wisconsin
-
Burlington, Wisconsin, United States, 53105
- Aurora Cancer Care-Southern Lakes VLCC
-
Cudahy, Wisconsin, United States, 53110
- Aurora Saint Luke's South Shore
-
Eau Claire, Wisconsin, United States, 54701
- Marshfield Medical Center-EC Cancer Center
-
Fond du Lac, Wisconsin, United States, 54937
- Aurora Health Center-Fond du Lac
-
Germantown, Wisconsin, United States, 53022
- Aurora Health Care Germantown Health Center
-
Grafton, Wisconsin, United States, 53024
- Aurora Cancer Care-Grafton
-
Green Bay, Wisconsin, United States, 54311
- Aurora BayCare Medical Center
-
Kenosha, Wisconsin, United States, 53142
- Aurora Cancer Care-Kenosha South
-
La Crosse, Wisconsin, United States, 54601
- Gundersen Lutheran Medical Center
-
Madison, Wisconsin, United States, 53792
- University of Wisconsin Carbone Cancer Center - University Hospital
-
Madison, Wisconsin, United States, 53718
- University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
-
Marinette, Wisconsin, United States, 54143
- Aurora Bay Area Medical Group-Marinette
-
Marshfield, Wisconsin, United States, 54449
- Marshfield Medical Center-Marshfield
-
Milwaukee, Wisconsin, United States, 53209
- Aurora Cancer Care-Milwaukee
-
Milwaukee, Wisconsin, United States, 53215
- Aurora Saint Luke's Medical Center
-
Milwaukee, Wisconsin, United States, 53233
- Aurora Sinai Medical Center
-
Minocqua, Wisconsin, United States, 54548
- Marshfield Medical Center - Minocqua
-
Mukwonago, Wisconsin, United States, 53149
- ProHealth D N Greenwald Center
-
New Richmond, Wisconsin, United States, 54017
- Cancer Center of Western Wisconsin
-
Oconomowoc, Wisconsin, United States, 53066
- ProHealth Oconomowoc Memorial Hospital
-
Oshkosh, Wisconsin, United States, 54904
- Vince Lombardi Cancer Clinic - Oshkosh
-
Racine, Wisconsin, United States, 53406
- Aurora Cancer Care-Racine
-
Rice Lake, Wisconsin, United States, 54868
- Marshfield Medical Center-Rice Lake
-
Sheboygan, Wisconsin, United States, 53081
- Vince Lombardi Cancer Clinic-Sheboygan
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Stevens Point, Wisconsin, United States, 54482
- Marshfield Medical Center-River Region at Stevens Point
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Summit, Wisconsin, United States, 53066
- Aurora Medical Center in Summit
-
Two Rivers, Wisconsin, United States, 54241
- Vince Lombardi Cancer Clinic-Two Rivers
-
Waukesha, Wisconsin, United States, 53188
- UW Cancer Center at ProHealth Care
-
Waukesha, Wisconsin, United States, 53188
- ProHealth Waukesha Memorial Hospital
-
Wauwatosa, Wisconsin, United States, 53226
- Aurora Cancer Care-Milwaukee West
-
West Allis, Wisconsin, United States, 53227
- Aurora West Allis Medical Center
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Weston, Wisconsin, United States, 54476
- Marshfield Medical Center - Weston
-
-
Wyoming
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Cheyenne, Wyoming, United States, 82001
- Cheyenne Regional Medical Center-West
-
Cody, Wyoming, United States, 82414
- Billings Clinic-Cody
-
Sheridan, Wyoming, United States, 82801
- Welch Cancer Center
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
Patients must have newly diagnosed, stage II-IV low-grade serous ovarian cancer (submission of pathology report[s] required). Ovarian cancer = ovarian, fallopian tube and primary peritoneal cancers
- NOTE: Patients with a prior history of serous borderline tumors but a new diagnosis of stage II-IV low-grade serous ovarian cancer are eligible
p53 immunohistochemistry (IHC) is required and must show nonaberrant pattern (nonaberrant p53 expression is consistent with normal/wildtype TP53)
- A copy of the pathology report that includes the diagnosis of low grade serous ovarian cancer and nonaberrant p53 IHC result must be submitted in RAVE. NOTE: If aberrant p53 expression is found on p53 IHC, the patient is NOT eligible (aberrant p53 expression is consistent with mutant TP53 and supports diagnosis of high grade serous ovarian cancer)
Appropriate stage for study entry based on the following diagnostic workup:
- History/physical examination within 14 days prior to registration;
- Radiographic tumor assessment within 28 days prior to registration. (23-MAY-2023)
- Age >= 18
- Patients must have undergone an attempt at maximal upfront cytoreductive surgery, with either optimal (=< 1 cm diameter residual disease/nodule) or suboptimal residual disease (> 1 cm diameter residual disease/nodule) status allowed
- Patients must have undergone a bilateral salpingo-oophorectomy
- Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1 or 2 within 14 days prior to registration
- Patients must be within =< 8 weeks of primary cytoreductive surgery at time of randomization
- Patients must be able to take per oral (P.O.) medications
- Absolute neutrophil count (ANC) greater than or equal to 1,500/mcl (within 14 days prior to registration)
- Platelets greater than or equal to 100,000 cells/mcl (within 14 days prior to registration)
- Creatinine less than or equal to 1.5 x upper limit of normal (ULN) (within 14 days prior to registration)
- Bilirubin less than or equal to 1.5 x ULN (within 14 days prior to registration)
- Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) less than or equal to 3 x ULN (within 14 days prior to registration)
- The patient or a legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information
- Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
Exclusion Criteria:
- Patients may not have received neoadjuvant or adjuvant chemotherapy or radiotherapy for the treatment of this disease
- Patients may not have received previous hormonal therapy for the treatment of this disease
- Patients with known hypersensitivity to letrozole or hypersensitivity/intolerance to carboplatin/paclitaxel therapy
Patients with severe cardiac disease:
- Myocardial infarction or unstable angina within 6 months prior to registration
- New York Heart Association (NYHA) class II or greater congestive heart failure
- Patients with known central nervous system metastases
- Patients with active (except for uncomplicated urinary tract infection) or uncontrolled systemic infection
- Patients with >= grade 2 baseline neuropathy
- Known human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Arm I (paclitaxel, carboplatin, letrozole)
Patients receive paclitaxel IV over 3 hours and carboplatin IV on day 1.
Cycles repeat every 21 days for up to 6 cycles.
Patients then receive letrozole PO QD in the absence of disease progression or unacceptable toxicity.
Patients undergo blood collection and tumor biopsy during screening as well as medical imaging throughout the study.
|
Given IV
Other Names:
Given IV
Other Names:
Undergo blood sample collection
Other Names:
Given PO
Other Names:
Undergo tumor biopsy
Other Names:
Undergo medical imaging
Other Names:
|
|
Experimental: Arm II (letrozole)
Patients receive letrozole PO QD.
Cycles repeat every 21 days for up to 6 cycles.
Patients then receive letrozole orally PO QD in the absence of disease progression or unacceptable toxicity as maintenance therapy.
Patients undergo blood collection and tumor biopsy during screening as well as medical imaging throughout the study.
|
Undergo blood sample collection
Other Names:
Given PO
Other Names:
Undergo tumor biopsy
Other Names:
Undergo medical imaging
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Progression-free survival (PFS)
Time Frame: Time from the randomized treatment assignment to documentation of disease progression (Response Evaluation Criteria in Solid Tumors 1.1) or death from any cause, whichever comes first, assessed up to 8 years
|
The PFS comparison will be assessed at the second interim and final analyses using a logrank test stratified by country and residual disease status.
Estimates for the letrozole/letrozole (L/L) vs paclitaxel/carboplatin/letrozole (CT/L) hazard ratio and its confidence interval will be obtained using a stratified Cox proportional hazards model.
Potential confounding factors, including the stratification factors, performance status and self-declared racial designation will be considered in a final exploratory model.
A forest plot of treatment hazard ratios with confidence intervals within subgroups will also be reported.
PFS will be characterized by treatment group with Kaplan-Meier plots and estimates of the median PFS.
|
Time from the randomized treatment assignment to documentation of disease progression (Response Evaluation Criteria in Solid Tumors 1.1) or death from any cause, whichever comes first, assessed up to 8 years
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Incidence of adverse events (AE)
Time Frame: Up to 8 years
|
The nature, frequency and degree of toxicity will be tabulated at the System Organ Class and AE Term levels using Common Terminology Criteria for Adverse Events version 5.0.
Each patient will be represented according the maximum grade observed for each term, within randomized treatment assignment.
Tabulations will show the number and percentage of patients by maximum grade, within their randomized treatment assignment.
|
Up to 8 years
|
|
Objective response rate (ORR)
Time Frame: Up to 8 years
|
Will be estimated as the binomial proportion of patients with best overall response of complete response (CR) or partial response (PR) among patients with measurable disease after cytoreductive surgery.
Response rates and their 95% Wilson-Score confidence intervals will be estimated for each treatment arm, using the randomized treatment assignment.
The odds-ratio for ORR in the L/L vs CT/L arms will be estimated from the multivariable logistic regression model adjusted for stratification factors.
|
Up to 8 years
|
|
Duration of response
Time Frame: Time from documentation of response under documentation of progression or death, which is observed first, assessed up to 8 years
|
Will be defined among patients with best overall response of CR or PR.
Comparison of response duration between the randomized treatment arms will be supported by Kaplan Meier methods, and the corresponding estimates for median duration and its 95% confidence intervals.
|
Time from documentation of response under documentation of progression or death, which is observed first, assessed up to 8 years
|
|
Overall survival (OS)
Time Frame: Time between randomization and death from any cause, assessed up to 8 years
|
Differences in OS across the randomized treatment groups will be assessed using Kaplan Meier methods, with median time to death estimates and the corresponding 95% confidence intervals.
The L/L vs CT/L hazard ratio will be estimated by a proportional hazards model stratified by the randomization stratification factors.
|
Time between randomization and death from any cause, assessed up to 8 years
|
|
Adherence to letrozole maintenance therapy
Time Frame: At cycles 1, 6, and 12
|
Will be quantified as the mean rate of adherence (MRA), calculated as the proportion of product not returned divided by the number of days since the previous visit at which study products were dispensed.
Currently, the letrozole is delivered in a 2.5 mg pill, and the recommended dose is 2.5 mg per day.
This outcome will be computed for each treatment cycle (generally 21 days).
The mean MRA will be compared between the randomized treatment groups using linear mixed model methods.
The model will be specified with a random patient effect, and fixed effects for randomized treatment indicator, time (cycle number) and the interaction, with an adjustment for the protocol stratification factors.
Primary interest is in the difference in mean (MRA) at cycles 1, 6 and 12 between the treatment group.
The results will be reported as the estimated mean (MRA) and 95% confidence intervals for each treatment/time combination.
Treatment differences within stratification factors may also be considered.
|
At cycles 1, 6, and 12
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Amanda N Fader, NRG Oncology
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
September 20, 2019
Primary Completion (Estimated)
February 1, 2027
Study Completion (Estimated)
February 1, 2028
Study Registration Dates
First Submitted
September 16, 2019
First Submitted That Met QC Criteria
September 18, 2019
First Posted (Actual)
September 19, 2019
Study Record Updates
Last Update Posted (Actual)
March 24, 2026
Last Update Submitted That Met QC Criteria
March 23, 2026
Last Verified
March 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Urogenital Diseases
- Genital Diseases
- Endocrine System Diseases
- Urogenital Neoplasms
- Neoplasms by Site
- Neoplasms
- Female Urogenital Diseases
- Female Urogenital Diseases and Pregnancy Complications
- Genital Diseases, Female
- Endocrine Gland Neoplasms
- Ovarian Diseases
- Adnexal Diseases
- Genital Neoplasms, Female
- Gonadal Disorders
- Fallopian Tube Diseases
- Ovarian Neoplasms
- Fallopian Tube Neoplasms
- Organic Chemicals
- Heterocyclic Compounds, 1-Ring
- Heterocyclic Compounds
- Investigative Techniques
- Clinical Laboratory Techniques
- Diagnostic Techniques and Procedures
- Diagnosis
- Surgical Procedures, Operative
- Azoles
- Cytological Techniques
- Cytodiagnosis
- Hydrocarbons
- Cycloparaffins
- Hydrocarbons, Alicyclic
- Hydrocarbons, Cyclic
- Terpenes
- Physical Phenomena
- Coordination Complexes
- Taxoids
- Cyclodecanes
- Diterpenes
- Health Care Economics and Organizations
- Diagnostic Techniques, Surgical
- Nitriles
- Electromagnetic Phenomena
- Magnetic Phenomena
- Electromagnetic Radiation
- Radiation
- Radiation, Ionizing
- Triazoles
- Economics
- Letrozole
- Carboplatin
- Paclitaxel
- Biopsy
- Specimen Handling
- X-Rays
- Taxes
Other Study ID Numbers
- NRG-GY019 (Other Identifier: CTEP)
- U10CA180868 (U.S. NIH Grant/Contract)
- NCI-2019-01460 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Yes
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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