Eosinophilic Cystitis Mimicking Urothelial Neoplasia

Eosinophilic Cystitis Mimicking Urothelial Neoplasia: A Retrospective Study

We explored the potential etiology, clinical and histopathology presentation of the eosinophilic cystitis cases, clinically mimicking urothelial neoplasia. Surgical procedure and clinical outcome also evaluated. T

Study Overview

• Status: Completed
• Conditions: Urinary Bladder Diseases
• Intervention / Treatment: Diagnostic test: Microscopic examination

Detailed Description

A pooled 22 patients diagnosed with eosinophilic cystitis on microscopic examination in our hospital during four years were retrospectively studied.We explored the potential etiology, clinical and histopathology presentation of the eosinophilic cystitis cases, clinically mimicking urothelial neoplasia. Surgical procedure and clinical outcome also evaluated. Transurethral resection of the lesions were performed and pathologically examined, we re-examined the studied cases and made a clinical correlation.

• Study Type: Observational
• Enrollment (Actual): 22

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 10 years to 90 years (ADULT, OLDER_ADULT, CHILD)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients from Al-Azhar Hospital Urology outpatient and inpatient clinic during 4 years ftarting from January 2017

Description

Inclusion Criteria:

• Clinically suspected urothelial neoplasia

Exclusion Criteria:

• Patients who did not complete the follow up period

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Eosinophil cell count	Each tissue slide is retrieved and examined to count the eosinphils in the submucosa, positive cases revelaed more than 90% eosinophils of the whole inflammatory cells	1 day

Collaborators and Investigators

• Sponsor: Al-Azhar University

Study record dates

Study Major Dates

• Study Start (ACTUAL): January 17, 2017
• Primary Completion (ACTUAL): January 15, 2021
• Study Completion (ACTUAL): January 20, 2021

Study Registration Dates

• First Submitted: June 3, 2021
• First Submitted That Met QC Criteria: June 3, 2021
• First Posted (ACTUAL): June 4, 2021

Study Record Updates

• Last Update Posted (ACTUAL): June 4, 2021
• Last Update Submitted That Met QC Criteria: June 3, 2021
• Last Verified: June 1, 2021

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Urologic Diseases; Cystitis; Urinary Bladder Diseases
• Other Study ID Numbers: AUH210501

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No