Emp-Activity: Empagliflozin Functional Capacity

February 1, 2024 updated by: Boehringer Ingelheim

Empagliflozin Functional Capacity - Non-Interventional Study

This is a multinational non-interventional study based on newly collected data to assess demographics, disease, and treatment pattern of patients with chronic Heart Failure (HF) in a two-cohort design: one cohort will receive first prescription of empagliflozin as routine therapy for HF, the other cohort will receive HF therapy with drugs with another mechanism of action. Treatment of HF according to routine practice is determined by the physician independent of the participation of the patient in this non-interventional study.

Study Overview

Status

Active, not recruiting

Conditions

Heart Failure

Intervention / Treatment

Drug: Empagliflozin

Study Type

Observational

Enrollment (Actual)

3451

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Bulgaria
- - Burgas, Bulgaria, 8000
    - Dr. Mircheva
  - Haskovo, Bulgaria, 6304
    - Dr. Yordanov
  - Kardjali, Bulgaria, 6600
    - MBAL Atanas Dafovski, Kardzhali
  - Kyustendil, Bulgaria, 2501
    - Dr. Krasteva
  - Lovech, Bulgaria, 5500
    - Dr. Todorov
  - Lovech, Bulgaria, 5500
    - Dr. Tsoneva
  - Parvomay, Bulgaria, 4270
    - Dr. Pavlov
  - Pazardzhik, Bulgaria, 4400
    - Medical Center, Pazardjik
  - Pernik, Bulgaria, 2300
    - Dr. Stankova
  - Pleven, Bulgaria, 5800
    - assoc.prof. Gospodinov
  - Pleven, Bulgaria, 5800
    - dr. Kostadinovska
  - Pleven, Bulgaria, 5800
    - prof.Tisheva
  - Plovdiv, Bulgaria, 4001
    - Dr. Mekenian
  - Plovdiv, Bulgaria, 4002
    - Dr. Ilchev
  - Plovdiv, Bulgaria, 4018
    - Dr. Hairabedian
  - Plovdiv, Bulgaria, 4020
    - Dr. Filipov
  - Sliven, Bulgaria, 8800
    - MBAL Sliven, Dr. Bletsova
  - Sofia, Bulgaria, 1000
    - Dr. Pancheva
  - Sofia, Bulgaria, 1000
    - prof. Velchev
  - Sofia, Bulgaria, 1202
    - dr. Georgieva
  - Sofia, Bulgaria, 1202
    - dr. Karchinova
  - Sofia, Bulgaria, 1202
    - prof.Vitlianova
  - Sofia, Bulgaria, 1233
    - dr. Petrusheva
  - Sofia, Bulgaria, 1407
    - dr. Garvanski
  - Sofia, Bulgaria, 1431
    - Dr. Naidenova
  - Sofia, Bulgaria, 1431
    - Dr. Varnaliiska
  - Sofia, Bulgaria, 1431
    - prof. Karamfiloff
  - Sofia, Bulgaria, 1784
    - Dr. Nossikov
  - Stara Zagora, Bulgaria, 6004
    - Dr. Gospodinov
  - Targovishte, Bulgaria, 7700
    - Dr. Trendafilova
  - Varna, Bulgaria, 9000
    - dr. Belcheva
  - Varna, Bulgaria, 9003
    - dr. Mancheva
  - Varna, Bulgaria, 9010
    - dr. Gyuzelev
  - Yambol, Bulgaria, 8600
    - Dr. Petrova
  - Yambol, Bulgaria, 8600
    - Dr. Toneva-Zhelaeva
Czechia
- - Brno, Czechia, 602 00
    - Fakultni nemocnice u sv. Anny v Brne
  - Brno, Czechia, 603 00
    - MUDr. Karel Kameník s.r.o.
  - Brno, Czechia, 61600
    - MUDr. Libor Nechvátal s.r.o.
  - Brno, Czechia, 62700
    - Zdravá srdce s.r.o.
  - Brno - Královo Pole, Czechia, 61200
    - Kardiologická ambulance Brno, s.r.o.
  - Broumov, Czechia, 55001
    - EDUMED s.r.o. - Dr. Nováková
  - Broumov, Czechia, 55001
    - EDUMED s.r.o. - Dr. Polášková
  - Broumov, Czechia, 55001
    - EDUMED s.r.o. - Dr. Švarcová
  - Broumov, Czechia, 55001
    - EDUMED s.r.o.
  - Bílovec, Czechia, 743 01
    - MUDr. Hana Burianová
  - Frýdek-Místek, Czechia, 73801
    - CorMedico s.r.o.
  - Havířov, Czechia, 73601
    - DIKa centrum s.r.o.
  - Havířov, Czechia, 73601
    - Lékařský servis, a.s.
  - Hlučín, Czechia, 748 01
    - Kardio Pudich s.r.o.
  - Hradec králové, Czechia, 50011
    - ProKardio HK, s.r.o.
  - Jihlava, Czechia, 58633
    - Nemocnice Jihlava - Kardiologické oddělení
  - Kolín, Czechia, 2802
    - Oblastní nemocnice Kolín, a.s. nemocnice Středočeského kraje
  - Louny, Czechia, 440 01
    - KardioBusak s.r.o.
  - Most, Czechia, 43401
    - Kardiomost s.r.o.
  - Nový Jičín, Czechia, 74101
    - Nemocnice AGEL Nový Jičín, a.s.
  - Olomouc, Czechia, 77900
    - Kardiologická ambulance Olomouc
  - Ostrava, Czechia, 70030
    - Nemocnice AGEL Ostrava-Vítkovice a.s. - Kardiologická ambulance
  - Ostrava, Czechia, 70200
    - Kardiologická ambulance Mammed
  - Ostrava, Czechia, 70200
    - OVAKARD s.r.o.
  - Ostrava, Czechia, 71900
    - Poliklinika Nová Huť
  - Ostrava - Poruba, Czechia, 708 52
    - Fakultni nemocnice Ostrava
  - Prague, Czechia, 120 00
    - Kardiologie Vinohrady s.r.o.
  - Praha 2, Czechia, 128 00
    - Vseobecna Fakultni Nemocnice v Praze
  - Praha 2, Czechia, 12000
    - Kardiologie prof. Táborský s.r.o.
  - Praha 4, Czechia, 140 00
    - Medicon a.s.
  - Praha 5, Czechia, 150 30
    - Nemocnice Na Homolce
  - Praha 5, Czechia, 15600
    - Clinical Trials Service s.r.o.
  - Prostejov, Czechia, 79604
    - ROcardia s.r.o.
  - Prostřední Suchá, Czechia, 73564
    - Galenica Medical s.r.o.
  - Trutnov, Czechia, 54101
    - Kardiologicka ambulance MUDr. Ferkl s.r.o.
  - Tábor, Czechia, 39003
    - Všeobecná interní ambulance s.r.o.
  - Třinec Podlesí, Czechia, 73961
    - Nemocnice AGEL Třinec-Podlesí a.s.
  - Vizovice, Czechia, 76312
    - Lunacor s.r.o.
  - Zlín, Czechia, 76275
    - Krajská nemocnice T. Bati, a.s.
  - Český Krumlov, Czechia, 38101
    - Kardiologická ambulance Český krumlov
  - Šumperk, Czechia, 78701
    - KARDIO GRÉZL, s.r.o.
Hungary
- - Balatonfüred, Hungary, 8230
    - Állami Szívkorhaz
  - Budapest, Hungary, 1096
    - Gottsegen György National Cardiovascular Center
  - Budapest, Hungary, 1122
    - Heart and Vascular Centre, Semmelweis University
  - Budapest, Hungary, 1133
    - Sante Cons Bt.
  - Debrecen, Hungary, 4032
    - DE Klinikai Központ Kardiológia és Szívsebészet
  - Dombóvár, Hungary, 7200
    - Dombóvári Szent Lukács Kórház
  - Dunavarsany, Hungary, 2336
    - Lahynara Bt
  - Eger, Hungary, 3300
    - Kardiológia Magánrendelő
  - Mohács, Hungary, 7700
    - Mohacsi Korhaz
  - Pécs, Hungary, 7624
    - University of Pecs
  - Pécs, Hungary, 7623
    - Coromed-Smo
  - Sopron, Hungary, 9400
    - Soproni Erzsébet Oktató Kórház
  - Szeged, Hungary, 6726
    - Újszeged Egészségközpont
Poland
- - Białystok, Poland, 15-028
    - ECHOKardio Poradnia Kardiologiczna
  - Białystok, Poland, 15-276
    - Klinika Kardiologii Uniwersyteckiego Szpitala Klinicznego w Białymstoku
  - Białystok, Poland, 15-546
    - Kardiologiczna Praktyka Lekarska Anna Tomaszuk-Kazberuk
  - Białystok, Poland, 15-875
    - Podlaski Ośrodek Kardiologii
  - Brzozów, Poland, 36-200
    - Specjalistyczna Praktyka Lekarska Marek Styczkiewicz
  - Bydgoszcz, Poland, 85-088
    - BlueMed - Centrum Medyczne
  - Bydgoszcz, Poland, 85-095
    - Centrum Kardiologii Paweł Grzelakowski
  - Bydgoszcz, Poland, 85-314
    - Centrum Medyczne A i D Nowak sj
  - Bydgoszcz, Poland, 85-791
    - Indywidualna Specjalistyczna Praktyka Lekarska Tomasz Ługowski
  - Bydgoszcz, Poland, 85-796
    - Specjalistyczna Praktyka Lekarska Grzegorz Grześk
  - Bytom, Poland, 41-902
    - Indywidualna Specjalistyczna Praktyka Lekarska Jolanta Nowak
  - Chorozow, Poland, 41500
    - Specjalistyczna Praktyka Lekarska Agata Fenger
  - Cieszyn, Poland, 43-400
    - Med. - Zone sp zoo
  - Czeladź, Poland, 41250
    - Specjalistyczna Praktyka Lekarska lek.n.med.Lucyna Góras-Hetmańczyk
  - Częstochowa, Poland, 42-202
    - Gabinet Kardiologiczny - Jacek Jafra
  - Częstochowa, Poland, 42-202
    - Prywatna Praktyka Lekarska Artur Dekiela
  - Dąbrowa Górnicza, Poland, 41-300
    - Specjalistyczna Praktyka Lekarska Magdalena Miczko
  - Gdynia, Poland, 81-395
    - ISPL Małgorzata Dobrowolska Gabinet Tendo
  - Gliwice, Poland, 44-100
    - Specjalistyczna Praktyka Lekarska Wojciech Czapla
  - Grodzisk Mazowiecki, Poland, 05-825
    - Indywidualna Praktyka Lekarska Tomasz Zieliński
  - Grójec, Poland, 05-600
    - Przychodnia Lekarska Zdrowy Miś
  - Głogów, Poland, 67-200
    - Miedziowe Centrum Zdrowia s.a.
  - Głogów Małopolski, Poland, 36-060
    - Centrum Medyczne NIWA
  - Inowrocław, Poland, 88-100
    - Indywidualna Praktyka Lekarska Piotr Tokarczyk
  - Iwanowice Włościańskie, Poland, 32-095
    - Familia Medicina Sp. z o.o.
  - Jastrzębie Zdrój, Poland, 44-330
    - Specjalistyczna Praktyka Lekarska Urszula Winiarska-Waluś
  - Jasło, Poland, 38-200
    - Specjalistyczna Praktyka Lekarska Jarosław Paździerz
  - Jędrzejów, Poland, 28-300
    - Dorota Adamczyk-Kot NZOZ-KARDIO
  - Kamień, Poland, 36-053
    - Centrum Medyczne Kinesis
  - Katowice, Poland, 40-645
    - Praktyka Lekarska Wojciech Kwaśniewski
  - Katowice, Poland, ul. Drozdów 26
    - Prywatna Przychodnia Specjalistyczna Drozd Zbigniew Gąsior
  - Kielce, Poland, 25-020
    - CUM PromontMed
  - Konin, Poland, 62-500
    - Arsmedica Specjalistyczna Praktyka Lekarska lek.med. Krzysztof Czerniejewski
  - Konin, Poland, 62-500
    - Prywatny Gabinet Kardiologiczny lek. med. Sławomir Kępski
  - Konin, Poland, 62-500
    - Specjalistyczna Praktyka Lekarska Paweł Michalski
  - Koszalin, Poland, 75-402
    - Uromed Sp Zoo
  - Koszalin, Poland, 75-604
    - Poliklinika MSWiA/Indywidualna Specjalistyczna Praktyka Lekarska Krzysztof Jarząbek
  - Koźminek, Poland, 62-840
    - Indywidualna Praktyka Lekarska Krzysztof Maślak
  - Kraków, Poland, 31-070
    - Centrum Medyczne Dietla 19 Sp. z o.o.
  - Kraków, Poland, 31-101
    - Centrum Twojego Zdrowia
  - Kraków, Poland, 31-216
    - Specjalistyczna Praktyka Lekarska "Kardiolek" Dr med. Piotr Wilkołek
  - Kraków, Poland, 31-513
    - CM Oficerskie
  - Kraków, Poland, 31-826
    - Poradnia Kardiologiczna, Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie
  - Kranse, Poland, 36-007
    - Prywatny Gabinet Kardiologiczny Dr n.med Janusz Bąk
  - Krościenko Wyżne, Poland, 38-422
    - Centrum Medyczne Dębina
  - Legnica, Poland, 59-220
    - Beata Mikłaszewicz&Dariusz Dąbrowski Cardiamed S.J.
  - Legnica, Poland, 59-220
    - NZOZ DUOMED S.C. Poradnia Kardiologiczna
  - Libiaz, Poland, 32-590
    - Prywatny Specjalistyczny Gabinet Kardiologiczno-Internistyczny
  - Lublin, Poland, 20-053
    - Kardiologiczna Praktyka Lekarska Wojciech Kula
  - Lublin, Poland, 20-143
    - NZOZ Sanus Jacek Madej Poradnia kardiologiczna
  - Lublin, Poland, 20-143
    - NZOZ Sanus Jacek Madej
  - Lublin, Poland, 20-400
    - Provivo Specjalistyczne Centrum Medyczne
  - Lublin, Poland, 59-300
    - Indywidualna Specjalistyczna Praktyka Lekarska - Renata Leniec
  - Mikołów, Poland, 43-190
    - Niepubliczny Zakład Opieki Zdrowotnej Specjalistyczne Gabinety lekarskie
  - Mirków, Poland, 55-095
    - Gabinet Lekarski Kardiologiczny
  - Modliszewice, Poland, 26-200
    - Prywatne Usługi Medyczne Jacek Morka
  - Moszczenica, Poland, 97-310
    - Indywidualna Specjalistyczna PraktyKa Lekarska-Piotr Utz
  - Nowe Miasto nad Pilicą, Poland, 26-420
    - Gabinet Lekarski Ewa Burchard
  - Nowy Tomyśl, Poland, 64-300
    - Medyczne Centrum Zdrovita
  - Oleśnica, Poland, 56-400
    - Oleśnica Prywatna Praktyka Lekarska
  - Ostrów Wielkopolski, Poland, 63-400
    - SZOZ Jantar Sp. z o.o. Poradnia Lekarzy Specjalistów
  - Oświęcim, Poland, 32-600
    - GVM CARINT Oświęcim
  - Piasek, Poland, 43-211
    - Specjalistyczna Praktyka Lekarska Rafał Nowak
  - Piotrków Trybunalski, Poland, 97-300
    - Specjalistyczna Praktyka Lekarska Andrzej Bęben
  - Poznań, Poland, 60-461
    - Indywidualna Specjalistyczna Praktyka Lekarska Andrzej Bolewski
  - Przemyśl, Poland, 37-700
    - Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu
  - Przeworsk, Poland, 37-200
    - Leszek Kaminski Specjalistyczny Gabinet Lekarski
  - Pszczyna, Poland, 43-200
    - Praktyka Lekarska Katarzyna Czarnecka
  - Pulawy, Poland, 24-100
    - Poradnia Kardiologiczna SPZOZ Pulawy
  - Puławy, Poland, 24-100
    - PCK - Puławskie Centrum Kardiologiczne Przychodnia Specjalistyczna
  - Płock, Poland, 09-402
    - Indywidualna Specjalistyczna Praktyka Lekarska Maciej Strawczyński
  - Radom, Poland, 26-600
    - Indywidualna Specjalistyczna Praktyka Lekarska Magdalena Poterala
  - Radom, Poland, 26-600
    - Poradnia Kardioogiczna Zegara Słonecznego
  - Radzionków, Poland, 41-922
    - Specjalistyczna Praktyka Lekarska Radzionków
  - Rybnik, Poland, 44-203
    - Indywidualna Specjalistyczna Praktyka Lekarska dr n. med. Alicja Gałuszka-Bilińska
  - Rybnik, Poland, 44-217
    - Specjalistyczna Praktyka Lekarska Wiesława Faberska-Blicharska
  - Rzeszów, Poland, 35-006
    - Centrum Medyczne Sabamed
  - Rzeszów, Poland, 35-055
    - Prywatny Gabinet Kardiologiczny dr n.med Janusz Romanek
  - Sanok, Poland, 38-500
    - My Life Centrum chorób serca
  - Siedlce, Poland, 08-110
    - Monika Kujawiak Prywatna Praktyka Lekarska
  - Siedlce, Poland, 08-110
    - Prywatny Gabinet Lekarski Hanna Wilk-Manowiec
  - Siemianowice Śląskie, Poland, 41-106
    - Indywidualna praktyka lekarska Artur Marcinkiewicz
  - Skierniewice, Poland, 96-100
    - Asnyka 78d Gabinety Lekarskie
  - Sosnowiec, Poland, 41-200
    - Specjalistyczna Praktyka Lekarska Maciej Kaźmierski
  - Sosnowiec, Poland, 41-200
    - Specjalistyczna Praktyka Lekarska Marek Kondys
  - Stalowa Wola, Poland, 37-450
    - Powiatowy Szpital Specjalistyczny w Stalowej Woli
  - Szczecin, Poland, 70-341
    - Centrum Medyczne VITA
  - Szczecin, Poland, 71-790
    - Specjalistyczna Praktyka Lekarska Tomasz Urbanik
  - Szczecin, Poland, 71-804
    - ISPL Anna Bis
  - Szczecinek, Poland, 78-400
    - Szpital w Szczecinku
  - Szczytniki, Poland, 62-023
    - Gabinet Lekarski Weronika Greberska
  - Tarnowskie Góry, Poland, 42-606
    - Leomed Centrum Medyczne
  - Tarnów, Poland, 33-100
    - Specjalistyczna Praktyka Lekarska Paweł Kocik
  - Toruń, Poland, 87-100
    - Prywatna Praktyka Lekarska na wezwanie Mirosław Marciniak
  - Tychy, Poland, 43-100
    - Indywidualna Specjalistyczna Praktyka Lekarska - Witold Orszulak
  - Tychy, Poland, 43100
    - Urszula Urbanowicz Specjalistyczna Praktyka Lekarska
  - Warszawa, Poland, 02-496
    - SERCE S.C. Przychodnia Lekarzy Specjalistów
  - Warszawa, Poland, 02-991
    - Klinika 37 Centrum Kardiologii Płowiecka
  - Warszawa, Poland, 04-188
    - Prywatny Gabinet Lekarski Bożena Norwa-Otto
  - Wawrzeńczyce, Poland, 32-125
    - Gabinet Lekarski lek med. Robert Włodarczyk
  - Wałbrzych, Poland, 58-302
    - Centrum Medyczne Nowe Miasto
  - Włocławek, Poland, 87-800
    - Specjalistyczny Gabinet Lekarski Łukasz Graczykowski
  - Zabrze, Poland, 10444
    - Specjalistyczna Prajtyka Lekarska Grażyna Glanowska
  - Zabrze, Poland, 41-800
    - Gabinet Prywatnej Praktyki Lekarskiej Kard.-Int . Dr n.med. Brygida Przywara-Chowaniec
  - Zamość, Poland, 22-400
    - Ns Zoz Kardiologia Sp. Z.O.O.
  - Zielona Góra, Poland, 65-001
    - ALDEMED Centrum Medyczne
  - Łańcut, Poland, 37-100
    - Poradnia Kardiologiczna Centrum Medyczne w Łańcucie
  - Łuków, Poland, 21-400
    - Kardiologiczno - Internistyczny Gabinet Lekarski Skrzyński Andrzej
  - Łódź, Poland, 90-302
    - Santa Sp. z o.o.
  - Łódź, Poland, 91-002
    - Nzoz Salusmed
  - Łęczna, Poland, 21-010
    - SP ZOZ Łęczna
  - Ścinawa, Poland, 59-330
    - Specjalistyczna Praktyka Lekarska Kamila Stembalska
  - Świebodzin, Poland, 66-200
    - Lekarze na Dworskiej
  - Żary, Poland, 68-200
    - Gabinety Lekarskie JM Kulczyccy
  - Żyrardów, Poland, 96-300
    - Prywatna Praktyka Lekarska Anna Chudoba
Romania
- - Alba-Iulia, Romania, 510137
    - Miclea Ioana - Mariana MEDIC SPECIALIST CARDIOLOG
  - Arad, Romania, 310009
    - Dr. Morar Mihnea-Dragoscabinet Medical Individual - Specialist Cardiologie
  - Arad, Romania, 310182
    - Dr. Pop-Moldovan Adina-Ligia - Medicina Interna - Cardiologie
  - Bacau, Romania, 600037
    - CMI Iosipescu Laura Cristina
  - Bacau, Romania, 600204
    - Cardio Animus SRL
  - Baia Mare, Romania, 430076
    - CMI - Centrul medical Diacord
  - Baia Mare, Romania, 430123
    - Mercea Corina-Delia - Medic
  - Botosani, Romania, 710095
    - Ambrinomed SRL
  - Brasov, Romania, 500326
    - Cardioland SRL
  - Brasov, Romania, RO-500188
    - Rus V. Horatiu - Cabinet Medical Individual de Cardiologie
  - Bucuresti, Romania, 010991
    - S.C. Ilro Medical S.R.L
  - Bucuresti, Romania, 011026
    - PFA Balahura Cristian
  - Bucuresti, Romania, 011258
    - Dr. Danet Ruxandra - Medic Cardiologie
  - Bucuresti, Romania, 011925
    - Dr. Bogdan Stefan Nicolae
  - Bucuresti, Romania, 012052
    - Cardiocare Center SRL
  - Bucuresti, Romania, 012082
    - Cordmedica SRL
  - Bucuresti, Romania, 020281
    - Dr. Serban Irina-Ruxandra - MEDIC PRIMAR CARDIOLOGIE
  - Bucuresti, Romania, 020281
    - Urocard Plus Srl
  - Bucuresti, Romania, 020501
    - Medi Pro Consult SRL
  - Bucuresti, Romania, 021705
    - Cmi Dr Georgescu Dragos
  - Bucuresti, Romania, 021967
    - Dr. Geavlete Dana-Oliviana - Activitate Medicala
  - Bucuresti, Romania, 030915
    - Mihaila I. Sorina - Medic Pfi
  - Bucuresti, Romania, 040343
    - S.C. Cardiomedical Team Pro S.R.L.
  - Bucuresti, Romania, 060926
    - Dumitrescu Silviu-Ionel Persoana Fizica Autorizata
  - Bucuresti, Romania, 061192
    - Mihalcea Janina-Diana Medic Specialist Cardiologie
  - Bucuresti, Romania, 061304
    - Patrascu R. Natalia - Medic Specialist Medicina Interna
  - Bucuresti, Romania, 061406
    - Popescu I. Ileana Nicoleta Medic specialist cardiologie
  - Bucuresti, Romania, 062282
    - CMI Dr. Parsa Motlagh Babak
  - Bucuresti, Romania, 070000
    - Magister Research SRL
  - Bucuresti, Romania, RO-011038
    - Dr. Lungeanu-Juravle Laura-Activitate Medicala
  - Buzau, Romania, 120203
    - Medcon SRL
  - Buzau, Romania, 120195
    - Cardio Clinique NCS SRL
  - Buzau, Romania, 120279
    - Medicard SRL
  - Ciurea, Romania, RO-707085
    - Angioplast Medical srl
  - Cluj Napoca, Romania, 400347
    - CMI Diaconescu Iulia Dana
  - Cluj Napoca, Romania, 400347
    - Mediprax Centrum Cluj Napoca
  - Cluj Napoca, Romania, 400347
    - SC Adisan SRL
  - Cluj Napoca, Romania, 400347
    - Sc Medicardio Andreea Srl
  - Cluj Napoca, Romania, 400349
    - Cardiotreat SRL
  - Cluj Napoca, Romania, 400394
    - SC Clujana Medica Srl
  - Cluj Napoca, Romania, 400441
    - PFA Comsa M.Dan-Horatiu
  - Cluj Napoca, Romania, 400479
    - Cabinet Cardiohealt Srl
  - Cluj Napoca, Romania, 400535
    - SC Cardioprotect MED SRL
  - Cluj Napoca, Romania, RO-400480
    - Sc Dentcor Srl
  - Com Mosoaia, Romania, 117512
    - Cardio World Health
  - Constanta, Romania, 610219
    - Cardio Manea Adelina SRL
  - Constanta, Romania, 900002
    - Endodiahealth Srl
  - Constanta, Romania, 900168
    - Dr. Maxim George Razvan - Activitate Medicala
  - Constanta, Romania, 900519
    - CMI Dr Ilie Ivona Valeria
  - Constanta, Romania, 900615
    - Asclepios Medicalhealth SRL
  - Craiova, Romania, 200085
    - Sc Daxiela Impex Srl
  - Craiova, Romania, 200323
    - Hortopan Med SRL
  - Craiova, Romania, 200383
    - Neurocord Medical SRL
  - Craiova, Romania, 200470
    - Vesalius Medical S.R.L
  - Craiova, Romania, 200519
    - Cabinet Medical Individual - Dr. Popescu Monica
  - Craiova, Romania, RO-200692
    - SC A&C Medical Prime SRL
  - Curtea de Arges, Romania, 115300
    - S & R Cardiobalance Srl
  - Deva, Romania, 330011
    - Cardiolife
  - Galati, Romania, 800217
    - SC Maycor SRL
  - Galati, Romania, 800584
    - CMI Dr. Chiscaneanu Teodor
  - Gheorghieni, Romania, 535500
    - Cardiomedplus SRL
  - Iasi, Romania, 700111
    - Procardia Serv-Med 2009 SRL srl
  - Iasi, Romania, 700260
    - Sc Cardiocare Clinic Srl
  - Iasi, Romania, 700282
    - Sc Cardiortomed Srl
  - Iasi, Romania, 700451
    - Medical Cardio Anghel SRL
  - Iasi, Romania, 700688
    - Niculescu G. Ana Irina - Medic colaborator
  - Iasi, Romania, 700732
    - SC Cardiomed SRL Iasi
  - Miercurea Ciuc, Romania, 530112
    - Cardioszakacs Srl, Cui 34404518
  - Odorheiu Secuiesc, Romania, 535600
    - Polimed Center SRL, CUI 26072639
  - Oradea, Romania, 410009
    - CMI Dr. Rotariu Dragos
  - Oradea, Romania, 410027
    - CMI Societatea civila Magheru&Magheru
  - Oradea, Romania, 410169
    - CMI Cardiomed SRL
  - Oradea, Romania, 410388
    - PFA Dr. Ardelean Adriana Ioana
  - Oradea, Romania, 410473
    - Dradiand SRL
  - Oradea, Romania, 410474
    - Sc Adriacard Srl
  - Ostratu, Romania, 012052
    - Simed Concept SRL
  - Piatra Neamt, Romania, 610065
    - Andries I. Elena - Medic Primar Cardiologie Si Medic Specialist Mi
  - Piatra Neamt, Romania, 610078
    - Cardiomed Alexandrescu Srl-D
  - Piatra Neamt, Romania, 610150
    - Dr. Corcoz Cardiologie SRL
  - Pitesti, Romania, 110003
    - Davisof San Srl
  - Pitesti, Romania, 110074
    - Clinica Cardiologie Dr Stanciu Viorel
  - Pitesti, Romania, 110172
    - Sc Procordia Concept Srl
  - Ploiesti, Romania, 100562
    - Cavi Clinique SRL
  - Ramnicu Valcea, Romania, 240022
    - SC Cardiologie Dr. Cristina Radoi SRL
  - Ramnicu Valcea, Romania, 240282
    - Sc Lidermed Plus Srl
  - Ramnicu Valcea, Romania, 240284
    - Sc Incarmed Srl
  - Sacele, Romania, 505600
    - Gx.Hatconsulting Srl
  - Sat Rosu, Comuna Chiajna, Romania, 077041
    - Munteanu Alice-Elena - Medic Cardiolog
  - Scheia, Romania, 720282
    - Voineag Olivia Medic Colaborator
  - Selimbar, Romania, 557260
    - Batar D. Sergiu Constantin
  - Sfintu Gheorghe, Romania, 520068
    - SC Endocordis SRL
  - Sinpetru, Romania, 507190
    - Cardio Stim Center SRL
  - Suceava, Romania, 720067
    - Rusu N. Ramona Iulia Medic Primar Cardiologie
  - Tifgu Mures, Romania, 540281
    - Diaconu Diana - Medic Cif 31885867
  - Timisoara, Romania, 300172
    - Cardiomed Health SRL
  - Timisoara, Romania, 300230
    - Mornos Cristian Medic Independent
  - Timisoara, Romania, 300244
    - Cardio Suport SRL
  - Timisoara, Romania, 300362
    - Medicalife Tim SRL
  - Timisoara, Romania, 300369
    - Cardio - DRS S.R.L
  - Timisoara, Romania, 300480
    - Policlinica Dr. Tudoran
  - Tirgu Mures, Romania, 540095
    - German Sallo Marta - Medic primar cardiolog, CIF 35699735
  - Tirgu Mures, Romania, RO-540496
    - CMI Tatar A. Maria Cristina, CUI 19814204
  - Turnu Severin, Romania, 220004
    - Bendl H. Laura Elena - Cabinet Medical Individual Plus Clinic
  - Valea Adinca, Romania, 700732
    - Croitoru G Rodica Medic Colaborator
  - Zalau, Romania, 450103
    - CMI Demle S. Adriana-Cristina
  - Zarnesti, Romania, 505800
    - Dr. Dragos Lupu - Medic Specialist Cardiolog
Switzerland
- - Basel, Switzerland, 4051
    - Universitatsspital Basel
  - Bern, Switzerland, 3006
    - Spital Sonnenhof
  - Bern, Switzerland, 3012
    - Engeried-Spital (Bern)
  - Biel, Switzerland, 2501
    - Spitalzentrum Biel
  - Carouge, Switzerland, 1227
    - Hôpital de La Tour
  - Courrendlin, Switzerland, 2830
    - Cardiomed - Jura
  - Delémont, Switzerland, 2800
    - Centre de Cardiologie
  - Frauenfeld, Switzerland, 8500
    - Schlossberg Ärztezentrum
  - Geneva 14, Switzerland, 1211
    - Hôpitaux Universitaires de Genève
  - Genève, Switzerland, 1205
    - Hôpitaux Universitaires de Genève
  - Genève 14, Switzerland, 1205
    - Hôpitaux Universitaires de Genève
  - Lachen, Switzerland, 8853
    - Spital Lachen AG
  - Lausanne, Switzerland, 1011
    - CHUV-Centre hospitalier universitaire vaudois
  - Luzern, Switzerland, 6004
    - Luzerner Kantonsspital
  - Luzern, Switzerland, 6006
    - Herzzentrum Hirslanden Zentralschweiz
  - Morges, Switzerland, 1110
    - Hôpital de Morges
  - Neuchâtel, Switzerland, 2000
    - Dr. med. Eleni Goulouti
  - Olten, Switzerland, 4600
    - Kantonsspital Olten
  - Regensdorf, Switzerland, 8105
    - Herzpraxis Regensdorf
  - Sarnen, Switzerland, 6060
    - Kantonsspital Obwalden
  - Seewis, Switzerland, 7212
    - Rehaklinik Seewis
  - Sierre, Switzerland, 3960
    - Dr. med. Kiril Tzvetanov
  - St. Gallen, Switzerland, 9000
    - Herzpraxis Sankt Gallen
  - Sursee, Switzerland, 6210
    - Herzpraxis Sursee
  - Thun, Switzerland, 3600
    - Spital STS AG
  - Thun, Switzerland, 3600
    - Kardiologie Aarezentrum Thun
  - Villars-sur-Glâne, Switzerland, 1752
    - Hôpital Fribourgeois
  - Wallisellen, Switzerland, 8304
    - Herz- und Physiozentrum
  - Waltenschwil, Switzerland, 5622
    - Arztpraxis Waltenschwil
  - Will, Switzerland, 9500
    - Spital Will
  - Winterthur, Switzerland, 8400
    - Herz- und Kreislaufpraxis Winterthur
  - Winterthur, Switzerland, 8400
    - Medbase Winterthur Neuwiesen
  - Yverdon-les-Bains, Switzerland, 1400
    - Hôpital d'Yverdon-les-Bains
  - Zollikerberg, Switzerland, 8125
    - Spital Zollikerberg
  - Zürich, Switzerland, 8091
    - Universitätsspital Zürich
  - Zürich, Switzerland, 8032
    - Herzklinik Hirslanden
  - Zürich, Switzerland, 8001
    - SICADE Clinic
  - Zürich, Switzerland, 8002
    - Herzpraxis Enge ZH
  - Zürich, Switzerland, 8008
    - Gruppenpraxis Dr. Deseö / Dr. Deseö-Schütz / Dr. Lorger
  - Zürich, Switzerland, 8032
    - HerzKlinik Zürich Hirslanden
  - Zürich, Switzerland, 8055
    - Herzkreislaufpraxis

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Sampling Method

Non-Probability Sample

Study Population

Patients with chronic Heart Failure (HF) in a two cohort design: one cohort will receive first prescription of empagliflozin as routine therapy for HF, the other cohort will receive HF therapy with drugs with another mechanism of action.

Description

Inclusion Criteria:

Written informed consent prior to study participation
Male and female patients ≥ 18 years at Visit 1
Patients must be contractually capable and mentally able to understand and follow the instructions of the study personnel
Patients with diagnosis of chronic heart failure NYHA Class 2-4
Treatment-naïve for SGLT2i at visit 1
Women of childbearing potential must take appropriate precautions against getting pregnant according to approval of chosen HF drug(s)

Exclusion Criteria:

Missing physician's diagnosis of chronic heart failure
Patients hospitalized at visit 1
Life expectancy ≤ 12 months according to physician's assessment
Lack of informed consent
Pregnant or lactating females
Participation in a parallel interventional clinical trial
Chosen treatment with another SGLT2i drug than empagliflozin
Having been enrolled into the non-empagliflozin-arm of this non-interventional study
Current or prior treatment with SGLT2i at visit 1
Patients with contraindications according to current Summary of Product Characteristics (SmPC)
Patients with dependency or relationship to the treating physician

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Observational Models: Cohort
Time Perspectives: Prospective

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Cohort receiving empagliflozin Patients will receive first prescription of empagliflozin as routine therapy for Heart Failure with reduced Ejection Fraction (HFrEF).	Drug: Empagliflozin Empagliflozin Other Names: Jardiance®
Cohort receiving drugs with another mechanism of action Patients will receive Heart Failure therapy with drugs with another mechanism of action.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change of Kansas City Cardiomyopathy Questionnaire (KCCQ) - Clinical summary score (CSS) in patients treated with empagliflozin Time Frame: At baseline, at week 24.	KCCQ is a 23-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life. The KCCQ-CSS is a combined score based upon the clinical symptoms and physical function domains of the questionnaire. The score is transformed to a range of 0 - 100, in which higher scores reflect better health status.	At baseline, at week 24.
Change in Kansas City Cardiomyopathy Questionnaire (KCCQ) total symptom score (TSS) in patients treated with empagliflozin Time Frame: At baseline, at week 24.	KCCQ is a 23-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life. The KCCQ-TSS incorporates the symptom frequency (4 items) and symptom burden (3 items) domains into a single summary score. The score is transformed to a range of 0-100, in which a higher score reflects better health status.	At baseline, at week 24.
Change in Kansas City Cardiomyopathy Questionnaire (KCCQ) overall summary score (OSS) 1 in patients treated with empagliflozin Time Frame: At baseline, at week 24.	KCCQ is a 23-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life. The KCCQ-OSS incorporates all domains into a score, ranging from 0-100, in which a higher score reflects better health status.	At baseline, at week 24.

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change of the New York Heart Association (NYHA) Class in patients treated with empagliflozin Time Frame: At baseline, at week 24.	Change of the New York Heart Association (NYHA) Class in patients treated with empagliflozin.	At baseline, at week 24.
Patient characteristics Time Frame: At baseline.	To evaluate patient characteristics in participants with chronic Heart Failure with reduced Ejection Fraction (HFrEF).	At baseline.
Frequency of comorbidities Time Frame: At baseline.	To evaluate the frequency of comorbidities in participants with chronic Heart Failure with reduced Ejection Fraction (HFrEF).	At baseline.
Treatment patterns Time Frame: At baseline.	To evaluate treatment patterns in participants with chronic Heart Failure with reduced Ejection Fraction (HFrEF).	At baseline.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Boehringer Ingelheim

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Related Info

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 15, 2022

Primary Completion (Estimated)

June 30, 2024

Study Completion (Estimated)

June 30, 2024

Study Registration Dates

First Submitted

April 22, 2022

First Submitted That Met QC Criteria

April 22, 2022

First Posted (Actual)

April 28, 2022

Study Record Updates

Last Update Posted (Actual)

February 2, 2024

Last Update Submitted That Met QC Criteria

February 1, 2024

Last Verified

January 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

1245-0259

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Once the criteria in section "Time Frame" are fulfilled, researchers can use the following link https://www.mystudywindow.com/msw/datasharing to request access to the clinical study documents regarding this study, and upon a signed "Document Sharing Agreement".

Furthermore, researchers can request access to the clinical study data, for this and other listed studies, after the submission of a research proposal and according to the terms outlined in the website.

IPD Sharing Time Frame

After structured results have been posted, all regulatory activities are completed in the US and EU for the product and indication, and after the primary manuscript has been accepted for publication.

IPD Sharing Access Criteria

For study documents - upon signing of a 'Document Sharing Agreement'. For study data - 1. after the submission and approval of the research proposal (checks will be performed by the sponsor and/or the independent review panel, including checking that the planned analysis does not compete with sponsor's publication plan); 2. and upon signing of a legal agreement.

IPD Sharing Supporting Information Type

STUDY_PROTOCOL
SAP
CSR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

product manufactured in and exported from the U.S.

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Study Overview

Status

Conditions

Intervention / Treatment

Study Type

Enrollment (Actual)

Contacts and Locations

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Sampling Method

Study Population

Description

Study Plan

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Collaborators and Investigators

Sponsor

Publications and helpful links

Helpful Links

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Estimated)

Study Completion (Estimated)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Actual)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

IPD Plan Description

IPD Sharing Time Frame

IPD Sharing Access Criteria

IPD Sharing Supporting Information Type

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product

product manufactured in and exported from the U.S.

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