- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05356312
Glioblastoma and Individualized Therapies
February 29, 2024 updated by: Zentrum fur Humangenetik Tuebingen
Retrospective Analysis of Glioblastoma Patients With Immune Therapies
The treatment of patients with World Health Organization (WHO) grade 4 malignant glioma has not seen any significant breakthrough the past years.
Following surgery and radio / chemotherapy patients still experience a very high recurrence risk and the prognosis is dismal.
The investigators observed patients with grade IV malignant glioma receiving individualized treatment based on their molecular profile including fully personalized vaccines.
Study Overview
Study Type
Expanded Access
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Tübingen, Germany
- Available
- Zentrum für Humangenetik Tübingen
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
N/A
Description
Inclusion Criteria:
- malignant glioma, IDH WT
Exclusion Criteria:
- na
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
April 11, 2022
First Submitted That Met QC Criteria
April 27, 2022
First Posted (Actual)
May 2, 2022
Study Record Updates
Last Update Posted (Actual)
March 1, 2024
Last Update Submitted That Met QC Criteria
February 29, 2024
Last Verified
February 1, 2024
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- GBM-RWD
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Glioma, Malignant
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City of Hope Medical CenterNational Cancer Institute (NCI); Food and Drug Administration (FDA)Active, not recruitingRecurrent Glioblastoma | Recurrent Malignant Glioma | Refractory Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Refractory Glioblastoma | Refractory WHO Grade II Glioma | Refractory WHO Grade III GliomaUnited States
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Henry FriedmanCompletedGrade IV Malignant GliomaUnited States
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Annick DesjardinsAmgenTerminated
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AmgenTerminatedGlioblastoma or Malignant GliomaUnited States, Australia, Netherlands, Germany, Spain, France
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Duke UniversityMonteris MedicalWithdrawnGlioblastoma | Malignant Glioma of BrainUnited States
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Jonsson Comprehensive Cancer CenterUnited States Department of DefenseActive, not recruitingGlioma | Malignant Glioma | Recurrent Malignant Glioma | Recurrent GliomaUnited States
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Kentuckiana Cancer InstituteEisai Inc.UnknownNewly Diagnosed Supratentorial Malignant GliomaUnited States
-
CellabMEDRecruitingRecurrent Malignant GliomaKorea, Republic of
-
University of ChicagoNational Institutes of Health (NIH)Active, not recruitingMalignant Glioma of BrainUnited States
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Radboud University Medical CenterCompleted
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Radboud University Medical CenterCompletedProstatic Neoplasms | Immunotherapy | Vaccines | Dendritic CellsNetherlands
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Charles University, Czech RepublicCompletedRecurrence | Cervical Intraepithelial Neoplasia Grade 2/3Czechia
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Temple UniversityNational Cancer Institute (NCI)Completed
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Radboud University Medical CenterDutch National Health Care InstituteNot yet recruitingLynch SyndromeNetherlands
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Jesús Moreno FernándezCastilla-La Mancha Health Service; University of Castilla-La ManchaCompletedType 1 Diabetes MellitusSpain
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Fondazione IRCCS Istituto Nazionale dei Tumori,...RecruitingCervical Cancer | HPV | Cervix Lesion | Vagina DiseaseItaly
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Children's Cancer Group, ChinaShanghai Pudong District Center for Disease Control and PreventionRecruitingHematologic Malignancy | Solid Tumor, Childhood | VaccinationChina