A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome (LIBREXIA-ACS)

April 9, 2026 updated by: Janssen Research & Development, LLC

A Phase 3, Randomized, Double-blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, After a Recent Acute Coronary Syndrome

The purpose of this study is to evaluate that milvexian is superior to placebo, in addition to standard-of-care, in reducing the risk of major adverse cardiovascular event (MACE) (the composite of cardiovascular [CV] death, myocardial infarction [MI], and ischemic stroke).

Study Overview

Status

Completed

Conditions

Acute Coronary Syndrome

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

14194

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Argentina
- - Bahía Blanca, Argentina, B8001HXM
    - Hospital Italiano Regional del Sur
  - Bahía Blanca, Argentina, 8000
    - Hospital Espanol De Bahia Blanca
  - Buenos Aires, Argentina, C1280AEB
    - Hospital Británico de Buenos Aires
  - Buenos Aires, Argentina, C1181ACH
    - Hospital Italiano de Buenos Aires
  - Buenos Aires, Argentina, C1187AAN
    - Sanatorio Finochietto
  - CABA, Argentina, C1180AAX
    - Sanatorio Güemes
  - Ciudad Autonoma Buenos Aires, Argentina, C1093AAS
    - Fundacion Favaloro
  - Ciudad Autonoma Buenos Aires, Argentina, C1430EGF
    - Clinica Adventista Belgrano
  - Ciudad Autonoma Buenos Aires, Argentina, 1425
    - Centro Medico Dra. Laura Maffei - Investigacion Clinica Aplicada
  - Ciudad Autonoma Buenos Aires, Argentina, 1428
    - Instituto Cardiovascular de Buenos Aires
  - Coronel Suárez, Argentina, B7540GHD
    - Clinica Coronel Suárez
  - Córdoba, Argentina, X5000JHQ
    - Sanatorio Allende
  - Córdoba, Argentina, X5016KEH
    - Hospital Privado Centro Médico de Córdoba
  - Córdoba, Argentina, 5000
    - Hospital San Roque
  - Córdoba, Argentina, 5000
    - Clínica Chutro
  - Córdoba, Argentina, X5006IKK
    - Centro Medico Luquez
  - Córdoba, Argentina, X5002HWE
    - Instituto Privado De Especialidades Medicas S.A. Fundacion J Robert Cade
  - Córdoba, Argentina, X5004CDT
    - Hospital Cordoba
  - Córdoba, Argentina, 5000
    - Sanatorio Duarte Quiroz
  - Córdoba, Argentina, X5000AAI
    - Clinica Romagosa
  - Córdoba, Argentina, X5000AAW
    - Clinica Privada del Prado
  - Córdoba, Argentina, X5000
    - Sanatorio de la Canada
  - La Plata, Argentina, B1900AXI
    - Hospital Italiano de La Plata
  - Mar del Plata, Argentina, B7600FYK
    - Centro de Investigaciones Medicas Mar del Plata
  - Quilmes, Argentina, B1878DKF
    - Sanatorio Modelo de Quilmes
  - Rosario, Argentina, S2000SDV
    - Sanatorio Parque
  - Rosario, Argentina, S2002KDS
    - Hospital Provincial del Centenario
  - Rosario, Argentina, S2000DSR
    - Instituto Cardiovascular de Rosario
  - Rosario, Argentina, S2001ODA
    - Hospital Italiano Garibaldi
  - Salta, Argentina, 4406
    - Centro Cardiovascular Salta
  - Salta, Argentina, 4400
    - Centro de Investigaciones Clinicas Salta
  - San Juan Bautista, Argentina, B1888AAE
    - Hospital El Cruce
  - San Martín, Argentina, 1650
    - Corporacion Medica de Gral. San Martin S.A.
  - San Miguel de Tucumán, Argentina, T4000ICL
    - Investigaciones Clinicas Tucuman
  - San Nicolás, Argentina, 2900
    - Estudios Clinicos de los Arroyos
  - Santa Fe, Argentina, S3000FUJ
    - Sanatorio Medico de Diagnostico y Tratamiento
  - Santa Fe, Argentina, S3000AZH
    - Sanatorio Mayo SA
  - Santa Fe, Argentina, S3000EOZ
    - Hospital José María Cullen
  - Venado Tuerto, Argentina, S2600KUE
    - Sanatorio San Martin
  - Villa María, Argentina, X5900JKA
    - Clinica Privada Fusavim SRL
Australia
- - Adelaide, Australia, 5000
    - Royal Adelaide Hospital
  - Adelaide, Australia, 5042
    - Flinders Medical Centre
  - Ballarat, Australia, 3350
    - Ballarat Base Hospital
  - Birtinya, Australia, 4575
    - Sunshine Coast University Hospital
  - Cairns, Australia, 4870
    - Cairns Base Hospital
  - Camperdown, Australia, 2050
    - Royal Prince Alfred Hospital
  - Concord, Australia, 2139
    - Concord Repatriation General Hospital
  - Garran, Australia, 2605
    - The Canberra Hospital
  - Herston, Australia, 4029
    - Royal Brisbane and Women's Hospital
  - Hobart, Australia, 7000
    - Royal Hobart Hospital
  - Kingswood, Australia, 2747
    - Nepean Hospital
  - Milton, Australia, 4064
    - Core Research Group
  - Murdoch, Australia, 6150
    - Fiona Stanley Hospital
  - Southport, Australia, 4215
    - Gold Coast University Hospital
  - Sydney, Australia, 2145
    - Westmead Hospital
  - Traralgon, Australia, 3844
    - Latrobe Regional Hospital
  - Wollongong, Australia, 2500
    - Wollongong Hospital
  - Woodville South, Australia, 5011
    - The Queen Elizabeth Hospital
Austria
- - Braunau am Inn, Austria, 5280
    - KH St.Josef Braunau am Inn
  - Feldkirch, Austria, A-6807
    - Landeskrankenhaus Feldkirch
  - Graz, Austria, 8036
    - Lkh-Univ. Klinikum Graz
  - Linz, Austria, 4020
    - Krankenhaus der Elisabethinen Linz
  - Vienna, Austria, 1090
    - Akh - Medizinische Universität Wien
Belgium
- - Bonheiden, Belgium, 2820
    - Imeldaziekenhuis
  - Brasschaat, Belgium, 2930
    - AZ KLINA
  - Bruges, Belgium, 8000
    - AZ Sint-Jan
  - Brussels, Belgium, 1200
    - Cliniques Universitaires Saint Luc
  - Brussels, Belgium, 1070
    - CUB Hôpital Erasme
  - Brussels, Belgium, 1090
    - Universitair Ziekenhuis Brussel
  - Brussels, Belgium, 1020
    - C.H.U. Brugmann
  - Genk, Belgium, 3600
    - Ziekenhuis Oost-Limburg
  - Ghent, Belgium, 9000
    - AZ Sint-Lucas
  - Hasselt, Belgium, 3500
    - Jessa Ziekenhuis
  - Liège, Belgium, 4000
    - CHR de la Citadelle
  - Mechelen, Belgium, 97770
    - Az Sint-Maarten
  - Mol, Belgium, 2400
    - Heilig Hart Ziekenhuis Lier
  - Mons, Belgium, 7000
    - CHU Ambroise Pare
  - Roeselare, Belgium, 8800
    - AZ Delta
  - Turnhout, Belgium, 2300
    - Az Turnhout
Brazil
- - Belo Horizonte, Brazil, 30380-090
    - Instituto das Pequenas Missionárias de Maria Imaculada - Hospital Madre Teresa
  - Belo Horizonte, Brazil, 30150-240
    - Cardresearch - Cardiologia Assistencial
  - Belo Horizonte, Brazil, 30140-062
    - Hospital Vera Cruz
  - Belo Horizonte, Brazil, 30140-073
    - IMINC Instituto Mineiro de Intervencao Cardiologica LTDA
  - Botucatu, Brazil, 18618-686
    - UNESP - Faculdade de Medicina da Universidade Estadual Paulista - Campus Botucatu
  - Brasília, Brazil, 70390903
    - Hospital do Coração do Brasil
  - Brasília, Brazil, 70710 149
    - Centro de Cardiologia Clinica e Pesquisa Doutora Juliana Souza Ltda CECAP Centro de Cardiologia Clinica
  - Campina Grande do Sul, Brazil, 83430-000
    - Sociedade Hospitalar Angelina Caron
  - Campinas, Brazil, 13060-080
    - Instituto de Pesquisa clinica de Campinas
  - Campinas, Brazil, 13010-001
    - C.E.C.-Centro Especializado em Cardiologia Ltda.- Loema Medicina e Bem Estar
  - Criciúma, Brazil, 88811-508
    - Sociedade Literaria e Caritativa Santo Agostinho Hospital Sao Jose
  - Curitiba, Brazil, 80010-030
    - Irmandade Santa Casa de Misericordia de Curitiba
  - Curitiba, Brazil, 80320-320
    - Hospital Cardiológico Costantini
  - Curitiba, Brazil, 80230-130
    - Associacao Paranaense de Cultura PUCPR
  - Goiânia, Brazil, 74605-020
    - Hospital das Clinicas da Universidade Federal de Goias
  - Marília, Brazil, 17515-000
    - Instituto do Coracao de Marilia
  - Natal, Brazil, 59020-035
    - Instituto Atena de Pesquisa Clinica
  - Passo Fundo, Brazil, 99010-120
    - Instituto Mederi de Pesquisa e Saude
  - Pelotas, Brazil, 96015 290
    - Santa Casa de Misericordia de Pelotas
  - Porto Alegre, Brazil, 90035-903
    - Hospital das Clinicas de Porto Alegre
  - Porto Alegre, Brazil, 90035-001
    - Associacao Hospitalar Moinhos de Vento
  - Porto Alegre, Brazil, 90160-092
    - Hospital Ernesto Dornelles
  - Porto Alegre, Brazil, 90620-001
    - Fundacao Universitaria de Cardiologia
  - Porto Alegre, Brazil, 91350 200
    - Hospital Nossa Senhora da Conceicao S A
  - Porto Alegre, Brazil, 90610-000
    - Uniao Brasileira de Educaçao e Assistência Hospital São Lucas da PUCRS
  - Porto Alegre, Brazil, 90110-270
    - IMV Pesquisa Cardiologica Sociedade Simples HMD COR l
  - Poços de Caldas, Brazil, 37701-033
    - Hospital Maternidade E Pronto Socorro Santa Lucia
  - Recife, Brazil, 50100-060
    - PROCAPE - Universidade de Pernambuco Pronto Socorro Cardiológico de Pernambuco prof Luiz Tavares
  - Recife, Brazil, 52051-380
    - Secretaria de Saude Hospital Agamenon Magalhaes
  - Ribeirão Preto, Brazil, 14098-900
    - Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP
  - Rio de Janeiro, Brazil, 22061-080
    - Hospital Sao Lucas
  - Salvador, Brazil, 41810-010
    - Fundacao Bahiana de Cardiologia
  - Salvador, Brazil, 40170310
    - Instituto CardioPulmonar
  - Salvador, Brazil, 41810011
    - Hospital Da Bahia
  - Salvador, Brazil, 40050-410
    - Hospital Santa Izabel Santa Casa de Misericordia da Bahia
  - Santo André, Brazil, 09080-110
    - Pesquisare Saude
  - São Bernardo do Campo, Brazil, 09715-090
    - CEMEC - Centro Multidisciplinar de Estudos Clínicos
  - São José, Brazil, 88103-460
    - Instituto de Cardiologia de Santa Catarina
  - São José do Rio Preto, Brazil, 15090-000
    - Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto Hospital de Base
  - São Paulo, Brazil, 01221-020
    - Irmandade Da Santa Casa De Misericordia De Sao Paulo
  - São Paulo, Brazil, 05403-000
    - Hospital das Clinicas da Faculdade de Medicina da USP
  - São Paulo, Brazil, 04012-909
    - Instituto Dante Pazzanese de Cardiologia
  - São Paulo, Brazil, 01323-903
    - Hospital Alemao Oswaldo Cruz
  - São Paulo, Brazil, 01323 900
    - Real e Benemérita Associação Portuguesa de Beneficência
  - São Paulo, Brazil, 08270-120
    - Casa de Saude Santa Marcelina - Hospital Santa Marcelina
  - São Paulo, Brazil, 01323 000
    - FGM Clinica Paulista de Doencas Cardiovasculares Ltda
  - São Paulo, Brazil, 05652000
    - Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein
  - Tatuí, Brazil, 18270-170
    - Instituto de Moléstias Cardiovasculares Tatuí
  - Uberaba, Brazil, 38025-350
    - HC-UFTM - Hospital de Clínicas da Universidade Federal do Triângulo Mineiro
  - Vitória, Brazil, 29702-020
    - Clinica Cardioped Ltda
  - Vitória, Brazil, Espírito Santo
    - CEDOES
  - Votuporanga, Brazil, 15500-003
    - Santa Casa de Misericórdia de Votuporanga
Bulgaria
- - Blagoevgrad, Bulgaria, 2700
    - MHAT Puls
  - Burgas, Bulgaria, 8000
    - MHAT Heart and brain
  - Gabrovo, Bulgaria, 5300
    - Multiprofile Hospital for Active Treatment Dr. Tota Venkova
  - Haskovo, Bulgaria, 6300
    - Multiprofile Hospital for Active Treatment - Haskovo
  - Panagyurishte, Bulgaria, 4500
    - MHAT Uni Hospital
  - Pernik, Bulgaria, 2300
    - SHATC Sveti Georgi-Pernik OOD
  - Pleven, Bulgaria, 5800
    - UMHAT 'Dr. Georgi Stranski', EAD
  - Pleven, Bulgaria, 5800
    - Multiprofile Hospital for Active Treatment Heart and Brain, Pleven
  - Plovdiv, Bulgaria, 4002
    - UMHAT 'Sv. Georgi' EAD
  - Plovdiv, Bulgaria, 4004
    - MHAT Sv. Karidad EAD
  - Sofia, Bulgaria, 1309
    - National Heart Hospital
  - Sofia, Bulgaria, 1750
    - University Multiprofile Hospital for Active Treatment- UMHAT Sveta Anna AD
  - Sofia, Bulgaria, 1431
    - Diagnostic Consultation Centre 'Alexandrovska' EOOD
  - Sofia, Bulgaria, 1527
    - University Multiprofile Hospital for Active Treatment - Tsaritsa Yoanna - ISUL, EAD
  - Sofia, Bulgaria, 1606
    - UMHATEM N I Pirogov
  - Sofia, Bulgaria, 1202
    - 2th MHAT - Sofia
  - Sofia, Bulgaria, 1431
    - UMHAT Prof. Dr. Aleksandar Chirkov
  - Sofia, Bulgaria, 1797
    - UMHAT Sofia Med
  - Stara Zagora, Bulgaria, 6003
    - UMHAT Prof. Dr. St. Kirkovich AD
Canada
- Alberta
  - Calgary, Alberta, Canada, T2N4N2
    - Foothills Hospital
  - Edmonton, Alberta, Canada, T6G 2B7
    - University of Alberta
- British Columbia
  - Surrey, British Columbia, Canada, V2V 0C6
    - Surrey Memorial Hospital
  - Vancouver, British Columbia, Canada, V5Z 1M9
    - Vancouver General Hospital
- Manitoba
  - Winnipeg, Manitoba, Canada, R2H 2A6
    - Saint Boniface General Hospital
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3J 3R4
    - Dalhousie University
- Ontario
  - Cambridge, Ontario, Canada, N1R 7R1
    - Dr. Saul Vizel Cardiac Research Office
  - Hamilton, Ontario, Canada, L8L 2X2
    - Hamilton Health Sciences Corporation
  - London, Ontario, Canada, N6A 5A5
    - London Health Sciences Centre
  - Newmarket, Ontario, Canada, L3Y 2R2
    - Southlake Regional Health Centre
  - Oakville, Ontario, Canada, L6M 0L8
    - Halton Healthcare Services Corporation
  - Ottawa, Ontario, Canada, K1Y 4W7
    - University of Ottawa Heart Institute
  - Peterborough, Ontario, Canada, K9J 0B2
    - Kawartha Cardiology Clinical Trials
  - St. Catharines, Ontario, Canada, L2S 0A9
    - Niagara Health System
  - Toronto, Ontario, Canada, M4N 3M5
    - Toronto Sunnybrook Hospital
  - Windsor, Ontario, Canada, N8X 5A6
    - Office of Dr. Anthony Glanz
- Quebec
  - Lévis, Quebec, Canada, G6V 4Z5
    - Clinique de Cardiologie de Lévis
  - Montreal, Quebec, Canada, H3G 1A4
    - Montreal General Hospital
  - Montreal, Quebec, Canada, H2L 4M1
    - Centre de recherche du CHUM
  - Québec, Quebec, Canada, G1V 4G5
    - Institut universitaire de Cardiologie et de Pneumologie de Quebec
  - Québec, Quebec, Canada, 00
    - Montreal Heart Institute
  - Québec, Quebec, Canada, G1J 1Z6
    - Centre de Recherche Clinique de Quebec
  - Saint-Jean-sur-Richelieu, Quebec, Canada, J3A1C3
    - CardioVasc HR
  - Terrebonne, Quebec, Canada, J6V 2H2
    - CSSS du Sud de Lanaudiere - Hopital Pierre-Le Gardeur d/b/a CISSS de Lanaudiere
  - Trois-Rivières, Quebec, Canada, G8Z 3R9
    - CIUSSS de la Mauricie-et-du-Centre-du-Quebec
- Saskatchewan
  - Saskatoon, Saskatchewan, Canada, S7N 0W8
    - Royal University Hospital
Chile
- - Puerto Varas, Chile, 5551070
    - Quantum Research
  - Santiago, Chile, 8330024
    - Centro de Investigacion Clinica Universidad Catolica de Chile CICUC
  - Temuco, Chile, 4780000
    - Centro de Estudios Cardiologicos y de Medicina Interna
  - Temuco, Chile, 4781156
    - Centro de Investigacion Clinica del Sur
  - Viña del Mar, Chile, 2520997
    - Centro de Estudios Clinicos V Region Ltda
China
- - Baotou, China, 014040
    - Baotou Central Hospital
  - Beijing, China, 100853
    - Chinese PLA General Hospital
  - Beijing, China, 100083
    - Peking University Third Hospital
  - Beijing, China, 100029
    - Beijing Anzhen Hospital, Capital Medical University
  - Beijing, China, 100034
    - Peking University First Hospital
  - Beijing, China, 100038
    - Beijing Shijitan Hospital
  - Beijing, China, 100050
    - Beijing Friendship Hospital Capital Medical University
  - Changchun, China, 130021
    - The First Hospital of Jilin University
  - Changzhou, China, 213000
    - Changzhou No 2 Peoples Hospital
  - Chengdu, China, 610041
    - West China Hospital Sichuan University
  - Chengdu, China, 610072
    - Sichuan Provincial Peoples Hospital
  - Chongqing, China, 400016
    - The First Affiliated Hospital of Chongqing Medical University
  - Dongguan, China, 523059
    - Dongguan People s Hospital
  - Fuzhou, China, 350005
    - The First Affiliated Hospital of Fujian Medical University
  - Guangzhou, China, 510080
    - Guangdong Provincial People's Hospital
  - Guangzhou, China, 510080
    - The First Affiliated Hospital of Sun Yat-sen University
  - Guiyang, China, 550000
    - The Affiliated Hospital of Guizhou Medical University
  - Guiyang, China, 550002
    - GuiZhou Privicial Peoples Hospital
  - Hangzhou, China, 310000
    - Zhejiang Provincial People's Hospital
  - Hangzhou, China, 310006
    - Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine
  - Hangzhou, China, 310016
    - Sir Run Run Shaw Hospital Zhejiang University School of Medicine
  - Hefei, China, 230001
    - Anhui Province Hospital
  - Huizhou, China, 516001
    - Huizhou Municipal Central Hospital
  - Jinan, China, 250012
    - Qilu Hospital of Shandong University
  - Jinan, China, 250033
    - The Second Affiliated Hospital, Shandong University
  - Jining, China, 272011
    - Shandong Jining No.1 People's Hospital
  - Lanzhou, China, 730030
    - Lanzhou University Second Hospital
  - Linfen, China, 041000
    - Linfen Central Hospital
  - Nanchang, China, 330006
    - The Second Affiliated Hospital of Nanchang University
  - Nanjing, China, 210029
    - Jiangsu Province Hospital
  - Nanjing, China, 210009
    - Zhongda Hospital Southeast University
  - Nanjing, China, 210000
    - Nanjing Drum Tower Hospital
  - Nanyang, China, 473000
    - The First Affiliated Hospital of Nanyang Medical College
  - Ningbo, China, 315010
    - Ningbo First Hospital
  - Shanghai, China, 200030
    - Shanghai Chest Hospital
  - Shanghai, China, 200032
    - Zhongshan Hospital Fudan University
  - Shanghai, China, 200011
    - Shanghai Ninth Peoples Hospital
  - Shantou, China, 515041
    - The First Affiliated Hospital of Shantou University Medical
  - Shenzhen, China, 518052
    - Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
  - Suzhou, China, 215006
    - The First Affiliated Hospital of Soochow University
  - Suzhou, China, 210009
    - The Second Affiliatted Hospital of Soochow University
  - Taiyuan, China, 030013
    - Shanxi Cardiovascular Hospital
  - Tianjin, China, 300052
    - Tianjin Medical University General Hospital
  - Tianjin, China, 300211
    - The Second Hospital of Tianjin Medical University
  - Tianjin, China, 300121
    - Tianjin People's Hospital
  - Tianjin, China, 300222
    - Tianjin Chest Hospital
  - Wenzhou, China, 325000
    - The First Affiliated Hospital of Wenzhou Medical University
  - Wenzhou, China, 325000
    - Wenzhou Peoples Hospital
  - Wuhan, China, 430014
    - The Central Hospital of Wuhan
  - Wuhan, China, 430033
    - Hubei Zhongshan Hospital The Third Peoples Hospital of Hubei Province
  - Wuxi, China, 214023
    - Wuxi People s Hospital
  - Xi'an, China, 710061
    - The First Affiliated Hospital of Xian Jiaotong University
  - Xinxiang, China, 453003
    - The Third Affiliated Hospital Of Xinxiang Medical University
  - Xuzhou, China
    - The Affiliated Hospital of Xuzhou Medical College
  - Yanji, China, 133000
    - Yanbian University Hospital
  - Yichang, China, 443003
    - Yichang Central Pepole's Hospital
  - Yinchuan, China, 750004
    - General Hospital of Ningxia Medical Hospital
  - Zhanjiang, China, 524001
    - Affiliated Hospital of Guangdong Medical University
  - Zhengzhou, China, 450052
    - The First Affiliated Hospital of Zhengzhou University
  - Zhongshan, China, 528403
    - Zhongshan City Peoples Hospital
  - Zunyi, China, 563000
    - Affiliated Hospital of Zunyi Medical University
Croatia
- - Dubrovnik, Croatia, 20000
    - General Hospital Dubrovnik
  - Krapinske Toplice, Croatia, 49217
    - Special Hospital for medical rehabilitation
  - Rijeka, Croatia, 51000
    - Clinical Hospital Centre Rijeka
  - Slavonski Brod, Croatia, 35000
    - General Hospital Slavonski Brod
  - Zagreb, Croatia, 10000
    - University Hospital Dubrava
  - Zagreb, Croatia, 10000
    - Poliklinika Solmed
Czechia
- - Brno, Czechia, 625 00
    - Fakultni Nemocnice Brno
  - Brno, Czechia, 636 00
    - Vojenska nemocnice Brno
  - Brno, Czechia, 65691
    - Fakultni nemocnice u sv. Anny v Brne
  - Hradec Králové, Czechia, 500 05
    - Fakultni nemocnice Hradec Kralove
  - Jihlava, Czechia, 586 01
    - Kardiocentrum Vysocina CZ a.s.
  - Kolín, Czechia, 280 02
    - Oblastní nemocnice Kolín
  - Liberec, Czechia, 46001
    - Krajska nemocnice Liberec a.s.
  - Ostrava-Poruba, Czechia, 708 52
    - Fakultni nemocnice Ostrava
  - Pardubice, Czechia, 530 03
    - Pardubicka krajska nemocnice a s
  - Pilsen, Czechia, 304 60
    - Fakultni nemocnice Plzen
  - Prague, Czechia, 12808
    - Vseobecna fakultni nemocnice v Praze
  - Prague, Czechia, 100 34
    - Fakultni nemocnice Kralovske Vinohrady
  - Prague, Czechia, 169 02
    - Ustredni vojenske nemocnice Praha
  - Prague, Czechia, 120 00
    - Kardiologie Vinohrady s r o
  - Prague, Czechia, 14000
    - Institut klinicke a experimentalni mediciny
  - Slaný, Czechia, 274 01
    - Nemocnice Slany
  - Třinec, Czechia, 73961
    - Nemocnice AGEL - Podlesi a.s.
  - České Budějovice, Czechia, 370 87
    - Nemocnice Ceske Budejovice a s
Denmark
- - Aahus N, Denmark, 8200
    - Aarhus University Hospital
  - Copenhagen S, Denmark, 2300
    - Amager Hospital
  - Frederiksberg, Denmark, 2000
    - Bispebjerg Og Frederiksberg Hospital
  - Herning, Denmark, 7400
    - Herning Regional Hospital
  - Holbæk, Denmark, 4300
    - Holbæk Sygehus
  - Hvidovre, Denmark, 2650
    - Hvidovre Hospital
  - Slagelse, Denmark, 4200
    - Slagelse Sygehus
  - Svendborg, Denmark, 5700
    - Odense University Hospital
  - Viborg, Denmark, 8800
    - Viborg Hospital
France
- - Angers, France, 49100
    - Chu Angers - Hôpital Hôtel Dieu
  - Caen, France, 14050
    - CH Prive Saint-Martin
  - Chambray-lès-Tours, France, 37170
    - CHRU de Tours - Hôpital Trousseau
  - Corbeil-Essonnes, France, 91106
    - Centre Hospitalier Sud Francilien
  - Créteil, France, 94000
    - Hôpital Henri Mondor
  - Dijon, France, 21033
    - CHU Dijon
  - La Tronche, France, 38700
    - CHU de Grenoble Hopital Albert Michallon
  - Le Coudray, France, 28630
    - CH de Chartres - Hôpital Louis Pasteur
  - Lille, France, 59037
    - CHRU de Lille Hopital Claude Huriez
  - Lyon, France, 69007
    - Centre Hospitalier Saint Joseph Et Saint Luc
  - Montauban, France, 82017
    - Clinique du Pont de Chaume
  - Montpellier, France, 34295
    - CHU de Montpellier Hopital Saint Eloi
  - Mulhouse, France, 68051
    - Centre Hospitalier Emile Muller
  - Nantes, France, 44093
    - CHU Nantes, Institut du thorax
  - Nice, France, 06002
    - Centre Hospitalier Universitaire - de Nice - Hopital Pasteur
  - Nîmes, France, 30029
    - Hopital Caremeau
  - Paris, France, 75018
    - Hôpital Bichat - Claude Bernard
  - Paris, France, 75012
    - Hôpital Saint-Antoine
  - Paris, France, 75010
    - Hôpital Lariboisière
  - Paris, France, 75679
    - Hôpital Cochin
  - Pau, France, 64046
    - Centre Hospitalier De Pau
  - Pessac, France, 33604
    - Hopîtal du Haut Lévêque
  - Poitiers, France, 86000
    - CHU Poitiers - Hôpital la Milétrie
  - Potigny, France, 14420
    - Hopital de Bicetre
  - Rouen, France, 78000
    - Clinique Saint-Hilaire - Centre Frédéric Joliot
  - Rouen, France, 76031
    - CHU Rouen Hopital Charles Nicolle
  - Strasbourg, France, 67200
    - Nouvel Hopital Civil - CHU Strasbourg
  - Toulouse, France, 31059
    - Hôpital Rangueil
  - Vandœuvre-lès-Nancy, France, 54500
    - CHU de Nancy - Hopital de Brabois
  - Versailles, France, 78157
    - Hopital Andre Mignot
Germany
- - Bad Friedrichshall, Germany, 74177
    - Klinikum am Plattenwald
  - Bad Krozingen, Germany, 79189
    - Universitaetsklinikum Freiburg
  - Bad Krozingen, Germany, 79189
    - Universitaetsklinikum Freiburg 1
  - Bad Nauheim, Germany, 61231
    - Kerckhoff-Klinik Bad Nauheim
  - Berlin, Germany, 13353
    - Charite Campus Virchow
  - Berlin, Germany, 10249
    - Vivantes Klinikum im Friedrichshain
  - Berlin, Germany, 13509
    - Vivantes Humboldt Klinikum
  - Berlin, Germany, 12200
    - Charite Campus Benjamin Franklin
  - Beuel, Germany, 53225
    - GFO Kliniken Bonn, Betriebsstaette St. Marien
  - Bielefeld, Germany, 33604
    - Klinikum Bielefeld
  - Bitburg, Germany, 54634
    - Marienhausklinikum Eifel Bitburg
  - Bonn, Germany, 53127
    - Universitätsklinikum Bonn
  - Brandenburg an der Havel, Germany, 14770
    - Staedisches Klinikum Brandenburg
  - Bremen, Germany, 28277
    - Hospital Bremen Mitte
  - Coburg, Germany, 96450
    - Regiomed Klinikum Coburg
  - Dortmund, Germany, 44137
    - St. Johannes-Hospital
  - Dresden, Germany, 01067
    - Staedtisches Klinikum Dresden Standort Dresden Friedrichstadt
  - Erfurt, Germany, 99097
    - Katholisches Krankenhaus St. Josef gGmbH - Abtlg. für Gynäkologie
  - Frankfurt, Germany, 60590
    - Klinikum der Johann Wolfgang Goethe -Universitaet
  - Greifswald, Germany, 17475
    - Universitaetsmedizin Greifswald
  - Hamburg, Germany, 20246
    - Universitaetsklinikum Hamburg Eppendorf
  - Hamburg, Germany, 22307
    - Asklepios Klinik Barmbek
  - Hamburg, Germany, 22587
    - Asklepios Klinik St. Georg
  - Leverkusen, Germany, 51375
    - Klinikum Leverkusen gGmbH
  - Ludwigshafen, Germany, 67063
    - Herzzentrum Ludwigshafen
  - Lüdenscheid, Germany, 58515
    - Klinikum Luedenscheid
  - Magdeburg, Germany, 39120
    - Universitätsklinikum Magdeburg
  - Mainz, Germany, 55131
    - Universitätsmedizin der Johannes Gutenberg Universität Mainz
  - Mainz, Germany, 55131
    - Katholisches Klinikum Mainz; Innere Medizin I- Kardiologie
  - Mannheim, Germany, 68167
    - Universitaetsklinikum Mannheim
  - Mönchengladbach, Germany, 41063
    - Kliniken Maria Hilf GmbH
  - Neuwied, Germany, 56564
    - Marienhaus Klinikum
  - Remscheid, Germany, 42859
    - Sana-Klinikum Remscheid GmbH
  - Rostock, Germany, 18057
    - Universitaetsmedizin Rostock
  - Tübingen, Germany, 72076
    - Universitaetsklinikum Tuebingen
  - Worms, Germany, 67550
    - Klinikum Worms gGmbH
Greece
- - Alexandroupoli, Greece, 68100
    - Uni General Hospital of Alexandroupolis
  - Athens, Greece, 15125
    - Athens Medical Center
  - Athens, Greece, 115 26
    - Henry Dunant Hospital
  - Athens, Greece, 11527
    - Hippokration Hospital
  - Athens, Greece, 12462
    - General Hospital of Athens Attikon
  - Athens, Greece, 16673
    - General Per Hospital of Athens Asklipiio Voulas
  - Athens, Greece, 115 27
    - General Hospital of Athens G Gennimatas
  - Athens, Greece, 14561
    - General Hospital of Attiki 'KAT'
  - Heraklion, Greece, 71110
    - University Hospital of Heraklion
  - Ioannina, Greece, 45500
    - University General Hospital of Ioannina
  - Larissa, Greece, 41110
    - University Hospital of Larissa
  - Pátrai, Greece, 26500
    - General University Hospital of Patras
  - Thessaloniki, Greece, 56429
    - Papageorgiou General Hospital
  - Thessaloniki, Greece, 54636
    - AHEPA University General Hospital of Thessaloniki
  - Thessaloniki, Greece, 57010
    - Papanikolaou General Hospital of Thessaloniki
  - Thessaloniki, Greece, 54642
    - Hippokration Hospital 1
Hungary
- - Budapest, Hungary, 1096
    - Gottsegen György Országos Kardiológiai Intézet
  - Budapest, Hungary, 1085
    - Semmelweis Egyetem
  - Budapest, Hungary, 1023
    - Budai Irgalmasrendi Korhaz
  - Budapest, Hungary, 1106
    - Bajcsy-Zsilinszky Korhaz es Rendelointezet
  - Budapest, Hungary, 1122
    - Semmelweis Egyetem Varosmajor Sziv es Ergyogyaszati Klinika
  - Debrecen, Hungary, 4032
    - Debreceni Egyetem
  - Gyula, Hungary, 5700
    - Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz
  - Kaposvár, Hungary, 7400
    - Somogy Megyei Kaposi Mor Oktato Korhaz
  - Kecskemét, Hungary, 6000
    - Bacs-kiskun Megyei Korhaz
  - Pécs, Hungary, 7624
    - Pécsi Tudományegyetem
  - Szeged, Hungary, 6725
    - Szegedi Tudomanyegyetem Aok Szent-Gyorgyi Albert Klinikai Kozpont
  - Szekszárd, Hungary, 7100
    - Tolna Megyei Balassa János Kórház
  - Szolnok, Hungary, 5000
    - Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointez
  - Szombathely, Hungary, 9700
    - Markusovszky Egyetemi Oktatokorhaz
  - Zalaegerszeg, Hungary, 8900
    - Belvarosi Egeszseghaz Kft. (Leda-Platan Maganklinika es Sebeszeti Kozpont)
India
- - Ahmedabad, India, 380006
    - NHL Medical College (SVP Hospital IMSR)
  - Aligarh, India, 202001
    - Jawaharlal Nehru Medical College and Hospital
  - Bangalore, India, 560069
    - Sri Jayadeva Institute
  - Belagavi, India, 590010
    - KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre (MRC)
  - Bikaner, India, 334003
    - S.P.Medical College & AG of Hospitals
  - Chennai, India, 600002
    - Tamil Nadu Government Multi Super Speciality Hospital
  - Chennai, India, 600006
    - Apollo Hospitals 1
  - Delhi, India, 110062
    - Batra Hospital and Medical Research Centre
  - Hyderabad, India, 500012
    - Osmania General Hospital
  - Hyderbad, India, 500034
    - Care Hospitals
  - Kochi, India, 682018
    - Lisie Hospital
  - Kolkata, India, 700020
    - IPGMER and SSKM Hospital
  - Kolkata, India, 700099
    - Rabindranath Tagore International Institute of Cardiac Sciences
  - Kolkata, India, 700014
    - NRS Medical college
  - Ludhiana, India, 141001
    - Dayanand Medical College & Hospital, Tagore Nagar, Civil Lines
  - Mangalore, India, 575001
    - Kasturba Medical College Hospital
  - Mumbai, India, 400012
    - Seth G S Medical College and KEM Hospital
  - Nagpur, India, 440010
    - Arneja Heart Institute
  - Nagpur, India, 440012
    - Crescent Hospital & Heart Center
  - Nagpur, India, 440015
    - Central India Cardiology Hospital and Research Institute
  - New Delhi, India, 110029
    - All India Institute of Medical Sciences
  - New Delhi, India, 110060
    - Sir Ganga Ram Hospital
  - Patna, India, 800014
    - Indira Gandhi Institute of Medical Sciences
  - Pune, India, 411001
    - Ruby Hall Clinic
  - Pune, India, 411011
    - KEM Hospital & Research Centre
  - Shimoga, India, 577205
    - Nanjappa Hospital
  - Surat, India, 395002
    - Unicare Heart Institute
  - Vijayawada, India, 520008
    - Government Siddhartha Medical College
  - Visakhapatnam, India, 530002
    - King George Hospital
Israel
- - Afula, Israel, 18101
    - HaEmek Medical Center
  - Ashdod, Israel, 7747629
    - Samson Assuta Ashdod University Hospital
  - Ashkelon, Israel, 78278
    - Barzilai Medical Center
  - Beersheba, Israel, 84101
    - Soroka University Medical Center
  - Haifa, Israel, 31096
    - Rambam Health Care Campus
  - Haifa, Israel, 31048
    - Bnai Zion Medical Center
  - Haifa, Israel, 3436212
    - Carmel Medical Center
  - Holon, Israel, 58100
    - Wolfson Medical Center
  - Jerusalem, Israel, 9103102
    - Shaare Zedek Medical Center
  - Jerusalem, Israel, 9124001
    - Hadassah Medical Center
  - Jerusalem, Israel, 9112001
    - Hadassah University Hospita Ein Kerem
  - Kfar Saba, Israel, 4428164
    - Meir Medical Center
  - Naharya, Israel, 2633737
    - Health Corporation of Galilee Medical Center
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center
  - Ramat Gan, Israel, 5262001
    - Chaim Sheba Medical Center
  - Rehovot, Israel, 7610001
    - Kaplan Medical Center
  - Rishon LeZiyyon, Israel, 70300
    - Assaf Harofeh Medical Center
  - Safed, Israel, 13100
    - Ziv Medical Center
  - Tiberias, Israel, 15208
    - Baruch Padeh Medical Center
Italy
- - Alessandria, Italy, 15121
    - Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo Alessandria
  - Bergamo, Italy, 24127
    - Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII)
  - Bergamo, Italy, 24125
    - Cliniche Humanitas Gavazzeni
  - Bologna, Italy, 40100
    - Azienda USL di Bologna - Ospedale Maggiore
  - Chieti, Italy, 66013
    - Universita D Annunzio
  - Ferrara, Italy, 44123
    - Azienda Ospedaliero-Universitaria di Ferrara Arcispedale Sant Anna
  - La Spezia, Italy, 19021
    - Ospedale Sant'Andrea
  - Mestre, Italy, 30035
    - Azienda Ulss 3 Serenissima distretto di Mirano
  - Milan, Italy, 20122
    - Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
  - Milan, Italy, 20138
    - Centro Cardiologico Monzino
  - Milan, Italy, 20162
    - Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda)
  - Naples, Italy, 80131
    - Azienda Ospedaliera Universitaria Federico Ii
  - Parma, Italy, 43100
    - Azienda Ospedaliero Universitaria di Parma
  - Pavia, Italy, 27100
    - Fondazione IRCCS Policlinico San Matteo
  - Pisa, Italy, 56124
    - A. O.U. Pisana Ospedale di Cisanello
  - Roma, Italy, 00161
    - AOU Policlinico Umberto I
  - Roma, Italy, 00168
    - Fondazione Policlinico Universitario A Gemelli IRCCS
  - Rozzano, Italy, 20089
    - Istituto Clinico Humanitas
  - Sassari, Italy, 07100
    - Ospedale San Francesco
  - Seriate, Italy, 24068
    - Ospedale Bolognini
  - Sesto San Giovanni, Italy, 20099
    - IRCCS Multimedica di Sesto San Giovanni
  - Torrette Di Ancona, Italy, 60126
    - Azienda Ospedaliero Universitaria Ospedali Riuniti
  - Treviglio, Italy, 24047
    - Azienda Ospedaliera Ospedale Treviglio-Caravaggio di Treviglio
Japan
- - Aichi, Japan, 486-8510
    - Kasugai Municipal Hospital
  - Amagasaki Shi, Japan, 660 8550
    - Hyogo Prefectural Amagasaki General Medical Center
  - Chiba, Japan, 260 8677
    - Chiba University Hospital
  - Chiba, Japan, 273 8588
    - Funabashi Municipal Medical Center
  - Chikushino-shi, Japan, 818-8516
    - Saiseikai Futsukaichi Hospital
  - Fukui-shi, Japan, 910-8526
    - Fukui Prefectural Hospital
  - Fukuoka, Japan, 812-8582
    - Kyushu University Hospital
  - Fukuoka, Japan, 811-0213
    - Fukuoka Wajiro Hospital
  - Fukuoka, Japan, 810 8563
    - National Hospital Organization Kyushu Medical Center
  - Gifu, Japan, 500-8717
    - Gifu Prefectural General Medical Center
  - Gunma, Japan, 370-0829
    - National Hospital Organization Takasaki General Medical Center
  - Himeji-shi, Japan, 670-8560
    - Hyogo Prefectural Harima-Himeji General Medical Center
  - Hiratsuka-shi, Japan, 254-8502
    - Hiratsuka Kyosai Hospital
  - Hirosaki, Japan, 036-8203
    - Hirosaki University Hospital
  - Hiroshima, Japan, 730-8518
    - Hiroshima City Hiroshima Citizens Hospital
  - Isehara, Japan, 259-1193
    - Tokai University Hospital
  - Ishikawa, Japan, 924-0865
    - Public Central Hospital of Matto Ishikawa
  - Itabashi Ku, Japan, 173 8606
    - Teikyo University Hospital
  - Izunokuni-shi, Japan, 410-2295
    - Juntendo University Shizuoka Hospital
  - Kamogawa, Japan, 2960041
    - Tesshokai Kameda Clinic
  - Kanagawa, Japan, 227-8501
    - Showa University Fujigaoka Hospital
  - Kanazawa, Japan, 920-0007
    - Asanokawa, Kanazawa Cardiovascular Hospital
  - Kasuga-shi, Japan, 816-0864
    - Fukuoka Tokushukai Hospital
  - Kisarazu-shi, Japan, 292-8535
    - Kimitsu Chuo Hospital
  - Kitakyushu-shi, Japan, 802-8555
    - Kokura Memorial Hospital
  - Kochi, Japan, 780-8522
    - Chikamori Hospital
  - Koga, Japan, 811-3195
    - National Hospital Organization Fukuoka Higashi Medical Center
  - Kumamoto, Japan, 861-4193
    - Saiseikai Kumamoto Hospital
  - Kumamoto, Japan, 860-8556
    - Kumamoto University Hospital
  - Kurashiki, Japan, 710-8602
    - Kurashiki Central Hospital
  - Kure-shi, Japan, 736-0023
    - National Hospital Organization Kure Medical Center and Chugoku Cancer Center
  - Kyoto, Japan, 606-8507
    - Kyoto University Hospital
  - Kyoto, Japan, 612-8555
    - National Hospital Organization Kyoto Medical Center
  - Matsudo-shi, Japan, 270-2251
    - Tokushukai Chiba-Nishi General Hospital
  - Matsumoto-shi, Japan, 390-8510
    - Jisenkai Aizawa Hospital
  - Meguro-ku, Japan, 153-8515
    - Toho University Medical Center, Ohashi Hospital
  - Minatoku, Japan, 108-0073
    - Tokyo Saiseikai Central Hospital
  - Miyazaki, Japan, 880-2102
    - Miyazaki Medical Association Hospital
  - Nagoya, Japan, 460-0001
    - NHO Nagoya Medical Center
  - Nagoya, Japan, 466-8650
    - Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital
  - Nishinomiya Shi, Japan, 663 8501
    - Hyogo Medical University Hospital
  - Okayama, Japan, 702-8055
    - Okayama Rosai Hospital
  - Osaka, Japan, 540-0006
    - National Hospital Organization Osaka National Hospital
  - Osaka, Japan, 534-0021
    - Osaka City General Hospital
  - Osaka, Japan, 543-0035
    - Osaka Police Hospital
  - Saga, Japan, 849-8501
    - Saga University Hospital
  - Sagamihara, Japan, 252-0375
    - Kitasato University Hospital
  - Saitama, Japan, 351-0102
    - National Hospital Organization Saitama National Hospital
  - Saitama-shi, Japan, 339-0033
    - Iwatsuki Minami Hospital
  - Sendai, Japan, 980 8574
    - Tohoku University Hospital
  - Shinagawa City, Japan, 142 8666
    - Showa University Hospital
  - Shinjuku-ku, Japan, 162-8666
    - Tokyo Women's Medical University Hospital
  - Shiwa-gun, Japan, 028-3695
    - Iwate Medical University Hospital
  - Suita-Shi, Japan, 564-8565
    - National Cerebral and Cardiovascular Center
  - Takamatsu, Japan, 760-8557
    - Kagawa Prefectural Central Hospital
  - Tokushima, Japan, 770-8503
    - Tokushima University Hospital
  - Tokyo, Japan, 152-8902
    - National Hospital Organization Tokyo Medical Center
  - Tokyo, Japan, 101-8643
    - Mitsui Memorial Hospital
  - Tokyo, Japan, 104 8560
    - St. Luke's International Hospital
  - Tokyo, Japan, 113 8603
    - Nippon Medical School Hospital
  - Tokyo, Japan, 173 8610
    - Nihon University Itabashi Hospital
  - Tokyo, Japan, 198-0042
    - Ome Medical Center
  - Toyama, Japan, 930-8550
    - Toyama Prefectural Central Hospital
  - Tsu, Japan, 514-8507
    - Mie University Hospital
  - Tsuchiura, Japan, 300-0028
    - Tsuchiura Kyodo General Hospital
  - Tsukuba, Japan, 305 8558
    - Tsukuba Medical Center Hospital
  - Ube, Japan, 755-8505
    - Yamaguchi University Hospital
  - Urayasu-shi, Japan, 279-0001
    - Tokyo Bay Urayasu Ichikawa Medical Center
  - Ureshino-shi, Japan, 843-0393
    - National Hospital Organization Ureshino Medical Center
  - Wakayama, Japan, 641 8510
    - Wakayama Medical University Hospital
  - Yokohama, Japan, 232 0024
    - Yokohama City University Medical Center
Latvia
- - Daugavpils, Latvia, LV5417
    - Daugavpils Regional Hospital
  - Riga, Latvia, LV1002
    - Pauls Stradins Clinical University Hospital
  - Riga, Latvia, LV-1038
    - Riga East Clinical University Hospital
Lithuania
- - Kaunas, Lithuania, LT-50161
    - Hospital of Lithuanian University of Health Sciences Kaunas Clinics
  - Klaipėda, Lithuania, LT-92288
    - Klaipeda Seamen's Hospital, Public Institution
  - Vilnius, Lithuania, LT-08661
    - Vilnius University Hospital Santariskiu Clinic, Public Institution
Malaysia
- - Kota Bharu, Malaysia, 15200
    - Hospital University Sains Malaysia
  - Kota Bharu, Malaysia, 15586
    - Hospital Raja Perempuan Zainab Ii
  - Kota Kinabalu, Malaysia, 88500
    - Hospital Queen Elizabeth
  - Kuala Lumpur, Malaysia, 59100
    - University Malaya Medical Centre
  - Kuala Lumpur, Malaysia, 50400
    - Institut Jantung Negara
  - Kuala Lumpur, Malaysia, 56000
    - Pusat Perubatan Universiti Kebangsaan Malaysia
  - Kuching, Malaysia, 93200
    - Sarawak General Hospital
  - Miri, Malaysia, 98000
    - Hospital Miri
  - Pulau Pinang, Malaysia, 10990
    - Hospital Pulau Pinang
  - Seberang Jaya, Malaysia, 13700
    - Hospital Seberang Jaya
  - Selayang Baru Utara, Malaysia, 68000
    - Universiti Teknologi Mara
Mexico
- - Aguascalientes, Mexico, 20230
    - Hospital Cardiologica Aguascalientes
  - Culiacán, Mexico, 80230
    - Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada S.C.
  - Mazatlán, Mexico, 82126
    - Centro de Estudios de de alta Especialidad de Sinaloa
  - Monterrey, Mexico, 64718
    - Private Practice Dr Amaya
  - México, Mexico, 14080
    - Instituto Nacional de Cardiologia Dr. Ignacio Chavez
  - Querétaro, Mexico, 76000
    - Centro de Estudios Clinicos de Queretaro S.C
  - San Luis Potosí City, Mexico, 78200
    - Centro de Atencion e Investigacion Cardiovascular del Potosi S C
  - Tijuana, Mexico, 22500
    - Centro de Investigacion Cardiovascular y Metabólica
  - Torreón, Mexico, 27000
    - Centro de Investigacion Dr. Alberto Esteban Bazzoni Ruiz
  - Xalapa, Mexico, 91193
    - Dr Enrique Lopez Rosas
Netherlands
- - 's-Hertogenbosch, Netherlands, 5223 GZ
    - Jeroen Bosch ziekenhuis
  - Alkmaar, Netherlands, 1815 JD
    - Noordwest Ziekenhuisgroep
  - Almelo, Netherlands, 7609PP
    - Ziekenhuisgroep Twente
  - Amersfoort, Netherlands, 3813 TZ
    - Meander Medisch Centrum
  - Amsterdam, Netherlands, 1091 AC
    - Onze Lieve Vrouwe Gasthuis
  - Deventer, Netherlands, 7416 SE
    - Deventer Ziekenhuis
  - Ede, Netherlands, 6716 RP
    - Ziekenhuis Gelderse Vallei
  - Eindhoven, Netherlands, 5623 EJ
    - Catharina Ziekenhuis
  - Emmen, Netherlands, 7824 AA
    - TREANT zorggroep
  - Enschede, Netherlands, 7512 KZ
    - Medisch Spectrum Twente
  - Goes, Netherlands, 4462 RA
    - Admiraal De Ruyter Ziekenhuis - Goes
  - Gouda, Netherlands, 2803 HH
    - Groene Hart Ziekenhuis
  - Harderwijk, Netherlands, 3844 DG
    - Ziekenhuis St Jansdal
  - Heerlen, Netherlands, 6419 PC
    - Zuyderland Medical Center
  - Helmond, Netherlands, 5707 HA
    - Elkerliek Ziekenhuis
  - Leiderdorp, Netherlands, 2353 GA
    - Alrijne Ziekenhuis Leiden ; Cardiology
  - Maastricht, Netherlands, 6229 HX
    - Maastricht UMC
  - Nieuwegein, Netherlands, 3435 CM
    - St. Antonius Ziekenhuis Nieuwegein
  - Nijmegen, Netherlands, 6525GA
    - Radboudumc
  - Roosendaal, Netherlands, 4708 AE
    - Bravis
  - Rotterdam, Netherlands, 3045 PM
    - Sint Franciscus Gasthuis
  - Sneek, Netherlands, 8601 ZR
    - D & A Research
  - Tiel, Netherlands, 4002 WA
    - Ziekenhuis Rivierenland
  - Utrecht, Netherlands, 3582 KE
    - Diakonessenhuis
  - Veldhoven, Netherlands, 5504 DB
    - Maxima Medisch Centrum
  - Venlo, Netherlands, 5912 BL
    - VieCuri Medisch Centrum
  - Zutphen, Netherlands, 7207
    - Gelre Ziekenhuizen Zutphen
New Zealand
- - Auckland, New Zealand, 1030
    - Auckland City Hospital
  - Auckland, New Zealand, 0740
    - North Shore Hospital
  - Christchurch, New Zealand, 4710
    - University of Otago
  - Dunedin, New Zealand, 9016
    - Dunedin Public Hospital
  - Hastings, New Zealand, 4120
    - Hawkes Bay Hospital
  - New Plymouth, New Zealand, 4342
    - Taranaki Base Hospital
  - Otahuhu, New Zealand, 2025
    - Middlemore Hospital
  - Rotorua, New Zealand, 3010
    - Rotorua Hospital
  - Tauranga, New Zealand, 3143
    - Tauranga Hospital
  - Whangarei, New Zealand, 110
    - Whangarei Hospital
North Macedonia
- - Skopje, North Macedonia, 1109
    - University Clinic of Cardiology
  - Tetovo, North Macedonia, 1200
    - Clinical Hospital Tetovo
Philippines
- - Angeles, Philippines, 2009
    - The Heart Specialists Clinic and Diagnostic Center
  - Cavite, Philippines, 4118
    - Silang Specialists Medical Center
  - Cebu, Philippines, 6000
    - Cebu Doctors University Hospital
  - Davao City, Philippines, 8000
    - Southern Philippines Medical Center
  - Davao City, Philippines, 8000
    - Davao Doctors Hospital
  - Davao City, Philippines, 8000
    - Central Lab Diabetes Wellness, Heart and Kidneys, Inc
  - Iloilo City, Philippines, 5000
    - St.Paul's Hospital-Iloilo
  - Lipa City, Philippines, 4217
    - Mary Mediatrix Medical Center
  - Mandaluyong, Philippines, 1552
    - Health Cube Medical Clinics
  - Manila, Philippines, 1000
    - Manila Doctors Hospital
  - Manila, Philippines, 1000
    - Medical Center Manila
  - Manila, Philippines, 1003
    - Chinese General Hospital & Medical Center
  - Manila, Philippines, 1000
    - Philippine General Hospital 1
  - Marikina City, Philippines, 1800
    - Amang Rodriguez Memorial Medical Center
  - Pasig, Philippines, 1605
    - The Medical City
  - Quezon, Philippines, 1102
    - St. Luke's Medical Center 1
  - San Juan City, Philippines, 1502
    - Cardinal Santos Medical Center
  - Santa Rosa, Philippines, 4026
    - The Medical City South Luzon
Poland
- - Bialystok, Poland, 15 276
    - Uniwersytecki Szpital Kliniczny W Bialymstoku
  - Bydgoszcz, Poland, 85 231
    - NZOZ Centrum Medyczne KERmed
  - Bytom, Poland, 41 902
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej
  - Elblag, Poland, 82 300
    - Wojewodzki Szpital Zespolony w Elblagu
  - Katowice, Poland, 40-156
    - Clinical Medical Research Sp. z o.o.
  - Kielce, Poland, 25-525
    - Specjalistyczna Poradnia Kardiologiczna i Nadcisnienia Tetniczego
  - Krakow, Poland, 30-082
    - Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska
  - Krakow, Poland, 30-693
    - Krakowskie Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii
  - Krakow, Poland, 31 202
    - Krakowski Szpital Specjalistyczny im Jana Pawla II
  - Lodz, Poland, 92-213
    - SPZOZ Centralny Szpital Kliniczny UM w Lodzi
  - Lublin, Poland, 20-954
    - Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie
  - Lublin, Poland, 20 049
    - 1 Wojskowy Szpital Kliniczny Z Poliklinika SPZOZ W Lublinie
  - Nałęczów, Poland, 24-140
    - NZOZ Osrodek Kardiologii Inwazyjnej -Ikardia
  - Olsztyn, Poland, 10-010
    - FutureMeds Olsztyn
  - Olsztyn, Poland, 10 561
    - Wojewodzki Szpital Specjalistyczny w Olsztynie
  - Oświęcim, Poland, 32-600
    - Medicome Sp. z o.o.
  - Poznan, Poland, 61 848
    - Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu
  - Przemyśl, Poland, 37-700
    - Wojewodzki Szpital im Sw Ojca Pio w Przemyslu
  - Siedlce, Poland, 08-110
    - Samodzielny Publiczny Szpital Wojewodzki im. Papieza Jana Pawla II
  - Skierniewice, Poland, 96-100
    - ETG Skierniewice
  - Sopot, Poland, 81 717
    - NZOZ PRO CORDIS Sopockie Centrum Badan Kardiologicznych
  - Torun, Poland, 87 100
    - Wojewodzki Szpital Zespolony im L Rydygiera w Toruniu
  - Warsaw, Poland, 04-628
    - Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy
  - Wałbrzych, Poland, 58 309
    - Specjalistyczny Szpital im dra Alfreda Sokolowskiego w Walbrzychu
  - Wroclaw, Poland, 51 124
    - Wojewodzki Szpital Specjalistyczny we Wroclawiu
  - Wroclaw, Poland, 50 368
    - Uniwersytecki Szpital Kliniczny Im Jana Mikulicza Radeckiego We Wroclawiu
  - Wroclaw, Poland, 50 981
    - 4 Wojskowy Szpital Kliniczny z Poliklinika SP ZOZ
Portugal
- - Aveiro, Portugal, 3814-501
    - Centro Hospitalar do Baixo Vouga E P E Unidade de Aveiro
  - Braga, Portugal, 4710-243
    - Hospital de Braga
  - Coimbra, Portugal, 3000-075
    - Uls Coimbra - Hosp. Univ. Coimbra
  - Covilha, Portugal, 6200-074
    - Centro Hospitalar Cova da Beira, EPE - Hospital Pêro da Covilhã
  - Guimarães, Portugal, 4835 044
    - Uls Alto Ave - Hosp. Sra. Da Oliveira Guimaraes
  - Leiria, Portugal, 2410-197
    - Centro Hospitalar de Leiria
  - Lisbon, Portugal, 1169-024
    - Centro Hospitalar de Lisboa Central
  - Lisbon, Portugal, 1649-035
    - Centro Hospitalar de Lisboa Norte Hospital Santa Maria
  - Santa Maria da Feira, Portugal, 4520-211
    - Centro Hospitalar de Entre o Douro e Vouga, E.P.E
  - Vila Nova de Gaia, Portugal, 4434-502
    - Centro Hospitalar de Vila Nova de Gaia Espinho E P E
  - Vila Real, Portugal, 5000-508
    - Centro Hospitalar de Trás os Montes e Alto Douro- Vila Real
Romania
- - Baia Mare, Romania, 430031
    - Spitalul Judetean de Urgenta Dr. Constantin Opris
  - Brasov, Romania, 500326
    - Spitalul Clinic Județean de Urgență Brașov
  - Bucharest, Romania, 014461
    - Spitalul Clinic de Urgenta Bucuresti
  - Bucharest, Romania, 010825
    - Spitalul Universitar de Urgenta Militar Central 'Dr. Carol Davila'
  - Bucharest, Romania, 011461
    - Spitalul Universitar de Urgenta Elias, Clinica de Cardiologie
  - Bucharest, Romania, 022328
    - Institutul de urgenta pentru Boli Cardiovasculare Prof. Dr. C.C. Iliescu
  - Cluj-Napoca, Romania, 400006
    - Spitalul Clinic Judetean de Urgenta Cluj Napoca
  - Cluj-Napoca, Romania, 400000
    - Spitalul Angiocare SRL
  - Constanța, Romania, 900591
    - Spitalul Clinic Judetean de Urgenta Sf. Apostol Andrei
  - Craiova, Romania, 200147
    - Spitalul Clinic Judetean De Urgenta Craiova
  - Iași, Romania, 700503
    - Institutul de Boli Cardiovasculare Iasi
  - Oradea, Romania, 410167
    - Spitalul Clinic Judetean de Urgenta Oradea
  - Piteşti, Romania, 110424
    - SAL MED Pitesti
  - Tg. Mures, Romania, 540136
    - Spitalul Clinic Judetean de Urgenta Targu Mures
  - Timișoara, Romania, 300310
    - Institutul de Boli Cardiovasculare Timișoara
  - Timișoara, Romania, 300043
    - Clinica Medicaliss
  - Timișoara, Romania, 300079
    - Spitalul Clinic Municipal de Urgenta Timisoara
  - Târgu Mureş, Romania, 540136
    - Spitalul Clinic Judetean de Urgenta Targu Mures 1
Serbia
- - Belgrade, Serbia, 11080
    - Clinical Hospital Center Zemun
  - Belgrade, Serbia, 11000
    - University Clinical Center of Serbia
  - Belgrade, Serbia, 11080
    - University Clinical Hospital Center Dr Dragisa Misovic- Dedi
  - Belgrade, Serbia, 11000
    - Institute for Cardiovascular diseases Dedinje
  - Belgrade, Serbia, 11000
    - Clinical Center Dr Dragisa Misovic Dedinje
  - Belgrade, Serbia, 11000
    - Institute for Cardiovascular diseases Dedinje 1
  - Belgrade, Serbia, 11000
    - University Clinical Center of Serbia 1
  - Belgrade, Serbia, 11000
    - University Clinical Center of Serbia 2
  - Kamenitz, Serbia, 21204
    - Institute of Cardiovascular Diseases of Vojvodina
  - Kamenitz, Serbia, 21204
    - Institute of Cardiovascular Diseases of Vojvodina 1
  - Kragujevac, Serbia, 34000
    - University Clinical Center Kragujevac
  - Niš, Serbia, 18000
    - Clinical Center Nis
  - Niš, Serbia, 18000
    - Clinical Center Nis 1
  - Niška Banja, Serbia, 18205
    - Institute for Treatment and Rehabilitation Niska Banja
  - Pančevo, Serbia, 26000
    - General Hospital Pancevo
  - Smederevo, Serbia, 11300
    - General Hospital Smederevo
  - Sremska Mitrovica, Serbia, 22000
    - General Hospital Sremska Mitrovica
  - Užice, Serbia, 31000
    - General Hospital Uzice
  - Zaječar, Serbia, 19000
    - Health Center Zajecar
Singapore
- - Singapore, Singapore, 119074
    - National University Hospital
  - Singapore, Singapore, 529889
    - Changi General Hospital
  - Singapore, Singapore, 609606
    - Ng Teng Fong General Hospital
  - Singapore, Singapore, 169609
    - National Heart Centre (NHC) Singapore
  - Singapore, Singapore, 768828
    - Khootech Puat Hospital
Slovakia
- - Banská Bystrica, Slovakia, 97401
    - Stredoslovensky ustav srdcovych a cievnych chorob a.s
  - Bardejov, Slovakia, 08501
    - Alian s.r.o.
  - Bratislava, Slovakia, 811 02
    - Premedix Clinic
  - Brezno, Slovakia, 977 01
    - Nemocnica s poliklinikou Brezno
  - Košice, Slovakia, 040 11
    - Východoslovenský Ústav Srdcových A Cievnych Chorôb, A.S.
  - Košice, Slovakia, 04001
    - Interno Kardio s r o
  - Košice, Slovakia, 4022
    - Kardiologicka ambulancia CARDIO D&R s.r.o.
  - Lučenec, Slovakia, 98439
    - KARDIO 1 s.r.o.
  - Martin, Slovakia, 036 59
    - Univerzitna nemocnica Martin 1
  - Moldava nad Bodvou, Slovakia, 4501
    - Kardiologicka ambulancia MEDI M&M s.r.o.
  - Nitra, Slovakia, 95001
    - Kardiocentrum Nitra s.r.o.
  - Nové Zámky, Slovakia, 94052
    - Cardioinvest s.r.o.
  - Svidník, Slovakia, 08901
    - Interna SK s.r.o.
  - Zvolen, Slovakia, 960 01
    - Nemocnica AGEL Zvolen a s
  - Žilina, Slovakia, 01001
    - MEDIVASA s.r.o.
South Africa
- - Cape Town, South Africa, 7500
    - TREAD Research
  - Cape Town, South Africa, 7530
    - Tiervlei Trial Centre
  - Cape Town, South Africa, 7500
    - Panorama MediClinic
  - Cape Town, South Africa, 7925
    - Groote Schur Hospital
  - Centurion, South Africa, 0157
    - Johese Clinical Research
  - Durban, South Africa, 4001
    - Durban Medical Centre
  - Johannesburg, South Africa, 2192
    - Garda, RA
  - Mossel Bay, South Africa, 6506
    - Eden Heart
  - Somerset West, South Africa, 7130
    - Dr J.M. Engelbrecht Trial Site
  - Somerset West, South Africa, 7130
    - Helderberg Research Institute
  - Worcester, South Africa, 6850
    - Clinical Projects Research SA (PTY) LTD
South Korea
- - Bucheon-si, South Korea, 14647
    - Bucheon St. Mary's Hospital
  - Busan, South Korea, 49241
    - Pusan National University Hospital
  - Busan, South Korea, 47392
    - Inje University Busan Paik Hospital
  - Busan, South Korea, 602 812
    - Dong-A University Hospital
  - Cheongju-si, South Korea, 28644
    - Chungbuk National University Hospital
  - Chuncheon, South Korea, 24289
    - Kangwon National University Hospital
  - Daegu, South Korea, 42601
    - Keimyung University Dongsan Hospital
  - Daejeon, South Korea, 35015
    - Chungnam National University Hospital
  - Daejeon, South Korea, 302-718
    - Konyang University Hospital
  - Gangseo-gu, South Korea, 7804
    - Ewha Woman's University Seoul Hospital
  - Goyang-si, South Korea, 10475
    - Myongji Hospital
  - Gwangju, South Korea, 61469
    - Chonnam National University Hospital
  - Gyeonggi-do, South Korea, 13620
    - Seoul National University Bundang Hospital
  - Incheon, South Korea, 21565
    - Gachon University Gil Medical Center
  - Incheon, South Korea, 403-720
    - The Catholic University of Korea, Incheon St. Mary'S Hospital
  - Sejong-si, South Korea, 30099
    - Chungnam National University Sejong Hospital
  - Seoul, South Korea, 03080
    - Seoul National University Hospital
  - Seoul, South Korea, 05505
    - Asan Medical Center
  - Seoul, South Korea, 02841
    - Korea University Anam Hospital
  - Seoul, South Korea, 06273
    - Gangnam Severance Hospital, Yonsei University Health System
  - Seoul, South Korea, 120-752
    - Severance Hospital Yonsei University Health System
  - Seoul, South Korea, 8308
    - Korea University Guro Hospital
  - Seoul, South Korea, 130 050
    - Kyung Hee University Hospital
  - Seoul, South Korea, 134-727
    - Kyung Hee University Hospital at Gangdong
  - Seoul, South Korea, 4763
    - Hanyang University Hospital
  - Seoul, South Korea, 05368
    - VHS Medical Center
  - Seoul, South Korea, 06591
    - Seoul St.Mary s Hospital
  - Wŏnju, South Korea, 220-701
    - Wonju Severance Christian Hospital
  - Yangsan, South Korea, 50612
    - Pusan National University Yangsan Hospital
Spain
- - Alicante, Spain, 03010
    - Hosp. Gral. Univ. de Alicante
  - Barcelona, Spain, 08025
    - Hosp. de La Santa Creu I Sant Pau
  - Barcelona, Spain, 08003
    - Hosp. Del Mar
  - Barcelona, Spain, 08036
    - Hosp Clinic de Barcelona
  - Barcelona, Spain, 08035
    - Hosp Univ Vall D Hebron
  - El Palmar, Spain, 30120
    - Hosp. Univ. Virgen de La Arrixaca
  - Gijón, Spain, 33206
    - Hosp. de Cabuenes
  - Lleida, Spain, 25198
    - Hosp. Univ. Arnau de Vilanova de Lleida
  - Madrid, Spain, 28040
    - Hosp. Clinico San Carlos
  - Madrid, Spain, 28041
    - Hosp. Univ. 12 de Octubre
  - Madrid, Spain, 28034
    - Hosp. Univ. Ramon Y Cajal
  - Madrid, Spain, 28046
    - Hosp. Univ. La Paz
  - Madrid, Spain, 28006
    - Hosp. Univ. de La Princesa
  - Madrid, Spain, 28660
    - Hosp. Univ. Hm Monteprincipe
  - Madrid, Spain, 28003
    - Hosp. Virgen de La Luz
  - Manises, Spain, 46940
    - Hosp. de Manises
  - Málaga, Spain, 29010
    - Hosp Virgen de La Victoria
  - Pamplona, Spain, 31008
    - Complejo Hosp. de Navarra
  - Santiago de Compostela, Spain, 15706
    - Hosp. Clinico Univ. de Santiago
  - Tarragona, Spain, 43007
    - Hosp. Univ. Joan Xxiii
  - Valencia, Spain, 46014
    - Hosp. Gral. Univ. Valencia
  - Valencia, Spain, 46010
    - Hosp. Clinico Univ. de Valencia 1
  - Vigo, Spain, 36312
    - Hosp. Alvaro Cunqueiro
  - Zaragoza, Spain, 50009
    - Hosp. Univ. Miguel Servet
Switzerland
- - Basel, Switzerland, 4031
    - Universitätsspital Basel
  - Bern, Switzerland, 3010
    - Universitätspital Bern, Universitätsklinik für Frauenheilkunde
  - Geneva, Switzerland, 1211
    - Hopitaux Universitaires de Geneve - HUG
  - Lugano, Switzerland, 6900
    - Istituto Cardiocentro Ticino
  - Zurich, Switzerland, 8091
    - Universitaetsspital Zuerich
Taiwan
- - Changhua, Taiwan, 50006
    - Changhua Christian Hospital
  - Kaohsiung City, Taiwan, 82445
    - E-Da Hospital
  - Kaohsiung City, Taiwan, 807
    - Kaohsiung Medical University Chung Ho Memorial Hospital
  - New Taipei City, Taiwan, 22060
    - Far Eastern Memorial Hospital
  - New Taipei City, Taiwan, 25160
    - Mackay Memorial Hospital
  - Taichung, Taiwan, 404327
    - China Medical University Hospital
  - Tainan, Taiwan, 71004
    - Chi Mei Medical Center Yong Kang
  - Taipei, Taiwan, 10002
    - National Taiwan University Hospital
  - Taipei, Taiwan, 11217
    - Taipei Veterans General Hospital
  - Taipei, Taiwan, 110
    - Taipei Medical University
  - Taipei, Taiwan, 112
    - Cheng Hsin General Hospital
  - Taipei, Taiwan, 106
    - Cathay General Hospital
  - Taipei, Taiwan, 116
    - Taipei Municipal Wanfang Hospital
  - Taipei, Taiwan, 114202
    - Tri-Service General Hospital
  - Taoyuan, Taiwan, 33305
    - Chang Gung Memorial Hospital- Linkou
  - Yilan County, Taiwan, 260
    - National Yang-Ming University Hospital
Thailand
- - Bangkok, Thailand, 10400
    - Ramathibodi hospital
  - Bangkoknoi, Thailand, 10700
    - Siriraj Hospital
  - Chiang Mai, Thailand, 50200
    - Maharaj Nakorn Chiang Mai Hospital
  - Nai Mueang Subdistrict Mueang, Thailand, 40000
    - Srinagarind Hospital
  - Pathum Wan, Thailand, 10330
    - King Chulalongkorn Memorial Hospital
Turkey (Türkiye)
- - Afyonkarahisar, Turkey (Türkiye), 03200
    - Afyon Kocatepe University Medical Faculty
  - Ankara, Turkey (Türkiye), 06100
    - Ankara University Medical Faculty
  - Ankara, Turkey (Türkiye), 06010
    - Ankara Etlik Speciality Hospital
  - Ankara, Turkey (Türkiye), 06800
    - Ankara Numune Research and Training Hospital
  - Bursa, Turkey (Türkiye), 16330
    - Bursa Yuksek Ihtisas Training and Research Hospital
  - Eskişehir, Turkey (Türkiye), 26480
    - Osmangazi University Medical Faculty
  - Istanbul, Turkey (Türkiye), 34899
    - Marmara University Pendik Training Hospital
  - Istanbul, Turkey (Türkiye), 34093
    - Bezmi Alem Vakif University Medical Faculty Hospital
  - Izmir, Turkey (Türkiye), 35340
    - Dokuz Eylul University Medical Faculty
  - Karabük, Turkey (Türkiye), 06100
    - Karabuk University Medical Faculty
  - Kayseri, Turkey (Türkiye), 38039
    - Erciyes University Medical Faculty
  - Kütahya, Turkey (Türkiye), 43040
    - Kutahya Health Science University Evliya Celebi Research and Training Hospital
  - Mersin, Turkey (Türkiye), 33020
    - Mersin University Medical Faculty
  - Samsun, Turkey (Türkiye), 55139
    - Ondokuz Mayis University
United Kingdom
- - Basingstoke, United Kingdom, RG24 9NA
    - Basingstoke and North Hampshire Hospital
  - Bath, United Kingdom, BA1 3NG
    - Royal United Hospital
  - Birmingham, United Kingdom, B9 5SS
    - Birmingham Heartlands Hospital
  - Birmingham, United Kingdom, B15 2WB
    - Queen Elizabeth Hospital
  - Blackpool, United Kingdom, FY3 8NR
    - Blackpool Victoria Hospital
  - Bournemouth, United Kingdom, BH7 7DW
    - Royal Bournemouth Hospital
  - Bristol, United Kingdom, BS1 3NU
    - University Hospital Bristol and Weston NHS trust
  - Dorchester, United Kingdom, DT1 2JY
    - Dorset County Hospital
  - Dudley, United Kingdom, DY1 2HQ
    - Russels Hall Hospital
  - East Kilbride, United Kingdom, G75 8RG
    - Hairmyres Hospital
  - Edinburgh, United Kingdom, EH16 4SA
    - Royal Infirmary of Edinburgh
  - Exeter, United Kingdom, EX2 5DW
    - Royal Devon and Exeter Hospital(Wonford)
  - Hampstead, United Kingdom, NW3 2QG
    - Royal Free Hospital
  - Harefield, United Kingdom, UB9 6JH
    - Harefield Hospital
  - Isleworth, United Kingdom, TW7 6AF
    - West Middlesex University Hospital
  - Kingston upon Thames, United Kingdom, KT2 7QB
    - Kingston Hospital
  - Leeds, United Kingdom, LS1 3EX
    - Leeds General Infirmary
  - Lincoln, United Kingdom, LN2 5QY
    - Lincoln County Hospital
  - London, United Kingdom, W12 0HS
    - Hammersmith Hospital
  - London, United Kingdom, EC1A 7BE
    - Barts Hospital
  - Londonderry, United Kingdom, BT47 6SB
    - Altnagelvin Hospital
  - Manchester, United Kingdom, M8 6RL
    - North Manchester General Hospital
  - Middlesbrough, United Kingdom, Ts4 3Bw
    - James Cook University Hospital
  - Newcastle upon Tyne, United Kingdom, NE7 7DN
    - Freeman Hospital
  - Peterborough, United Kingdom, PE3 9GZ
    - Peterborough City Hospital
  - Plymouth, United Kingdom, PL6 8DH
    - Derriford Hospital
  - Portsmouth, United Kingdom, PO6 3LY
    - Queen Alexandra Hospital
  - Redhill, United Kingdom, RH1 5RH
    - East Surrey Hospital
  - Stevenage, United Kingdom, SG1 4AB
    - Lister Hospital
  - Swansea, United Kingdom, SA6 6NL
    - Morriston Hospital
  - Taunton, United Kingdom, TA1 5DA
    - Musgrove Park Hospital
  - Torquay, United Kingdom, TQ2 7AA
    - Torbay Hospital-Devon
  - West Bromwich, United Kingdom, B71 4HJ
    - Sandwell and West Birmingham Hospitals NHS Trust-Sandwell Gene
  - Wigan, United Kingdom, WN1 2NN
    - Royal Albert Edward Infirmary
  - Yeovil, United Kingdom, BA214AT
    - Yeovil District Hospital
United States
- Alabama
  - Alexander City, Alabama, United States, 35010
    - Advanced Cardiovascular, LLC
  - Birmingham, Alabama, United States, 35205
    - Ascension St. Vincent's Health System
  - Birmingham, Alabama, United States, 35203
    - SORRA Research
  - Mobile, Alabama, United States, 36604
    - IMC-Diagnostic and Medical Clinic
  - Mobile, Alabama, United States, 36608
    - Cardiology Associates of Mobile Inc
- Arizona
  - Gilbert, Arizona, United States, 85297
    - Mercy Gilbert Medical Center
  - Phoenix, Arizona, United States, 85008
    - Valleywise Health Medical Center
  - Scottsdale, Arizona, United States, 85258
    - HonorHealth Neurology
- Arkansas
  - Little Rock, Arkansas, United States, 72211
    - Arkansas Heart Hospital
- California
  - Bakersfield, California, United States, 93306
    - Bakersfield Memorial Hospital
  - Fremont, California, United States, 94538
    - Mission Cardiovascular Research Institute
  - Newport Beach, California, United States, 92663
    - Radin Cardiovascular Medical Group
  - Northridge, California, United States, 91325
    - Valley Clinical Trials, Inc.
  - Palo Alto, California, United States, 94304
    - VA Palo Alto Healthcare System
  - Palo Alto, California, United States, 94304
    - Stanford University School of Medicine
  - Pasadena, California, United States, 91105
    - Huntington Hospital
  - Redding, California, United States, 96001
    - The Cardiovascular Center
  - San Diego, California, United States, 92123
    - San Diego Cardiac Center
  - San Diego, California, United States, 92103
    - University of California San Diego
  - San Diego, California, United States, 92161
    - VA San Diego Health Care System
  - Santa Monica, California, United States, 90401
    - UCLA
  - Santa Rosa, California, United States, 95405
    - NorthBay Clinical Research, LLC
  - Stockton, California, United States, 95204
    - Ramin Manshadi, MD
- Colorado
  - Littleton, Colorado, United States, 80120
    - South Denver Cardiology Associates PC
- Connecticut
  - Danbury, Connecticut, United States, 06810
    - Nuvance Health Medical Practices Cardiology Danbury
  - Stamford, Connecticut, United States, 06905
    - Cardiology Associates of Fairfield County, P.C.
- District of Columbia
  - Washington D.C., District of Columbia, United States, 20037
    - George Washington University Medical Center
- Florida
  - Boca Raton, Florida, United States, 33434
    - FWD Clinical Research
  - Clearwater, Florida, United States, 33756
    - Clearwater Cardiovascular Consultants
  - Fort Lauderdale, Florida, United States, 33308
    - Holy Cross Hospital Inc.
  - Fort Lauderdale, Florida, United States, 33312
    - Integrative Research Associates
  - Gainesville, Florida, United States, 32610-0236
    - University of Florida Health Jacksonville
  - Hialeah, Florida, United States, 33014
    - Inpatient Research Clinic LLC
  - Jacksonville, Florida, United States, 32209
    - Shands Jacksonville Medical Center Inc dba UF Health Jacksonville
  - Loxahatchee Groves, Florida, United States, 33470
    - Cardiology Partners Clinical Research Institute
  - Miami, Florida, United States, 33173
    - Baptist Hospital of Miami
  - Naples, Florida, United States, 34102
    - Advanced Research for Health Improvement
  - North Miami Beach, Florida, United States, 33169
    - Amavita Clinical Research (Dr. Pedro Martinez-Clark)
  - Pembroke Pines, Florida, United States, 33028
    - South Florida Research Solutions LLC
  - Safety Harbor, Florida, United States, 34695
    - Coastal Cardiology Consultants
  - Sarasota, Florida, United States, 34239-3513
    - Cardiovascular Center of Sarasota
  - Tampa, Florida, United States, 33614
    - Tampa Cardiovascular Interventions and Research
  - Trinity, Florida, United States, 34655
    - Interventional Cardiac Consultants
  - Wellington, Florida, United States, 33449
    - Cardiology Partners Clinical Research Institute 1
- Georgia
  - Atlanta, Georgia, United States, 30303
    - Grady Memorial Hospital
  - Cartersville, Georgia, United States, 30121
    - Atlanta Clinical Research Center
  - Gainesville, Georgia, United States, 30501
    - Northeast Georgia Heart Center
  - Thomasville, Georgia, United States, 31792
    - Cardiovascular Consultants of South Georgia LLC
- Idaho
  - Coeur d'Alene, Idaho, United States, 83814
    - Kootenai Medical Center
- Illinois
  - Chicago, Illinois, United States, 60616
    - Insight Hospital and Medical Center Chicago
  - Chicago, Illinois, United States, 60657
    - Illinois Heart and Vascular Foundation
  - Downers Grove, Illinois, United States, 60515
    - Advocate Heart Institute
  - Gurnee, Illinois, United States, 60031
    - Clinical Investigation Specialists, Inc.
  - Palos Hills, Illinois, United States, 60465
    - Essential Concepts Research Solutions
  - Peoria, Illinois, United States, 61636
    - Methodist Medical Center of Illinois
  - Peoria, Illinois, United States, 61614
    - OSF HealthCare Cardiovascular Institute
  - Springfield, Illinois, United States, 62701
    - Prairie Cardiovascular Consultants, Ltd.
  - Urbana, Illinois, United States, 61801
    - Carle Foundation Hospital
- Indiana
  - Elkhart, Indiana, United States, 46514-2487
    - Midwest Cardiovascular Research Foundation
  - Fort Wayne, Indiana, United States, 46804
    - Northern Indiana Research Alliance
  - Muncie, Indiana, United States, 47303
    - IU Health Ball Memorial Hospital
  - Richmond, Indiana, United States, 47374
    - Reid Health
- Kansas
  - Overland Park, Kansas, United States, 66209
    - Health Midwest Ventures Group, Inc d b a HCA MidAmerica Division, LLC
- Kentucky
  - Louisville, Kentucky, United States, 40202
    - University of Louisville
  - Louisville, Kentucky, United States, 40205
    - Norton Cardiovascular Associates
- Louisiana
  - Alexandria, Louisiana, United States, 71301
    - Cambridge Medical Trials
  - Houma, Louisiana, United States, 70360
    - Cardiovascular Institute of the South
  - New Orleans, Louisiana, United States, 70121
    - Ochsner Clinic And Hospital
  - Slidell, Louisiana, United States, 70458
    - Louisiana Heart Center
  - West Monroe, Louisiana, United States, 71291
    - Monroe Research LLC
- Maine
  - Bangor, Maine, United States, 04401
    - Eastern Maine Medical Center Northeast Cardiology Associates
- Maryland
  - Baltimore, Maryland, United States, 21231
    - Johns Hopkins University School of Medicine
  - Bethesda, Maryland, United States, 20814
    - Suburban Hospital
  - Lanham, Maryland, United States, 20706
    - Captiol Cardiology Associates
  - Rockville, Maryland, United States, 20850
    - Shady Grove Office
  - Salisbury, Maryland, United States, 21801
    - Tidal Health Peninsula Regional Inc.
- Massachusetts
  - Haverhill, Massachusetts, United States, 01830
    - Pentucket Medical Associates
- Michigan
  - Ann Arbor, Michigan, United States, 48109
    - University of Michigan
  - Bloomfield Hills, Michigan, United States, 48302
    - St. Joseph Mercy Oakland
  - Flint, Michigan, United States, 48504
    - AAMRC
  - Jackson, Michigan, United States, 39216
    - Jackson Heart Clinic
  - Lansing, Michigan, United States, 48912-1811
    - Sparrow Clinical Research Institute
- Minnesota
  - Duluth, Minnesota, United States, 55802-2207
    - St. Luke's Cardiology Associates
  - Saint Paul, Minnesota, United States, 55102
    - HealthEast Medical Research Institute
- Missouri
  - Chesterfield, Missouri, United States, 63017
    - Mercy Medical Research Institute
  - Columbia, Missouri, United States, 65211
    - The Curators of the University of Missouri on behalf of University of Missouri Health Care
  - Kansas City, Missouri, United States, 64116
    - North Kansas City Hospital
  - Kansas City, Missouri, United States, 64118
    - Spectrum Clinical Research
  - Springfield, Missouri, United States, 65807
    - Cox Health
  - St Louis, Missouri, United States, 63110
    - Saint Louis University
- Nebraska
  - Lincoln, Nebraska, United States, 68506
    - Bryan LGH Heart Institute
  - Omaha, Nebraska, United States, 68114
    - Methodist Physicians Clinic Heart Consultants
- Nevada
  - Las Vegas, Nevada, United States, 89102
    - University Medical Center of Southern Nevada
- New Jersey
  - Brick, New Jersey, United States, 08724
    - Ash Research Clinic
  - Englewood, New Jersey, United States, 07631
    - Englewood Health
  - Newark, New Jersey, United States, 07112
    - Newark Beth Israel Medical Center
  - Pomona, New Jersey, United States, 08240
    - AtlantiCare Regional Medical Center
  - Somerset, New Jersey, United States, 08873
    - Cardio Metabolic Institute
- New York
  - Buffalo, New York, United States, 14203-1154
    - Buffalo General Medical Center
  - Jamaica, New York, United States, 11418
    - Jamaica Hospital Medical Center
  - New York, New York, United States, 10032
    - Columbia University Medical Center
  - New York, New York, United States, 10065
    - Weill Cornell Medicine
  - New York, New York, United States, 10065
    - Weil Cornell University
  - Poughkeepsie, New York, United States, 12601
    - Hudson Valley Cardiovascular Practice, PC
  - The Bronx, New York, United States, 10469
    - Cardiac Care & Vascular Medicine, PLLC
  - Valhalla, New York, United States, 10532
    - Westchester Medical Center
- North Carolina
  - Cary, North Carolina, United States, 27518
    - Clinical Trials of America 1
  - Chapel Hill, North Carolina, United States, 27599-5021
    - UNC School of Medicine
  - Greensboro, North Carolina, United States, 27401
    - The Moses H. Cone Memorial Hospital
  - High Point, North Carolina, United States, 27262
    - Atrium Health Wake Forest Baptist
  - Lenoir, North Carolina, United States, 28645
    - Clinical Trials of America
  - Matthews, North Carolina, United States, 28105
    - Novant Health
  - Raleigh, North Carolina, United States, 27607
    - Rex Hospital
  - Sanford, North Carolina, United States, 27330
    - Sanford Cardiology
- North Dakota
  - Minot, North Dakota, United States, 58701
    - Trinity Medical Group
- Ohio
  - Akron, Ohio, United States, 44304
    - Summa Health System
  - Cincinnati, Ohio, United States, 45267
    - University of Cincinnati
  - Cleveland, Ohio, United States, 44109
    - Metro Health Hospital
  - Columbus, Ohio, United States, 43214
    - Ohio Health
  - Kettering, Ohio, United States, 45429
    - Kettering Medical Center
  - Springfield, Ohio, United States, 45504
    - The Heart House
- Oklahoma
  - Bartlesville, Oklahoma, United States, 74006
    - Ascension Medical Group - St. John Clinic Infectious Disease
  - Oklahoma City, Oklahoma, United States, 73135
    - South Oklahoma Heart Research
  - Tulsa, Oklahoma, United States, 74104
    - St John Health System Inc
- Pennsylvania
  - Bethlehem, Pennsylvania, United States, 18017
    - Advanced Cardiac Care
  - Chambersburg, Pennsylvania, United States, 17201
    - Chambersburg Hospital
  - Erie, Pennsylvania, United States, 16507
    - Hamot Medical Center
  - Harrisburg, Pennsylvania, United States, 17110
    - UPMC Pinnacle Health
  - Langhorne, Pennsylvania, United States, 19047
    - St. Mary Medical Center
  - Philadelphia, Pennsylvania, United States, 19104
    - Penn Presbyterian Medical Center
  - Wynnewood, Pennsylvania, United States, 19096
    - Lankenau Institute for Medical Research
- South Carolina
  - Anderson, South Carolina, United States, 29621
    - AnMed Health
  - Greenville, South Carolina, United States, 29607
    - St. Francis Physician Services, Inc, DBA Upstate Cardiology Research
  - Greenville, South Carolina, United States, 29065
    - Prisma Health
  - Rock Hill, South Carolina, United States, 29732
    - Carolina Cardiology Associates
- South Dakota
  - Rapid City, South Dakota, United States, 57701
    - Monument Health Clinical Research
- Tennessee
  - Chattanooga, Tennessee, United States, 37403
    - Erlanger Health System
  - Jackson, Tennessee, United States, 38301
    - Apex Cardiology
  - Nashville, Tennessee, United States, 37232
    - Vanderbilt University
  - Nashville, Tennessee, United States, 37205
    - Ascension Saint Thomas West Hospital
  - Oak Ridge, Tennessee, United States, 37830
    - Parkway Cardiology Associates PC
- Texas
  - Amarillo, Texas, United States, 79109
    - PharmaTex Research
  - Amarillo, Texas, United States, 79106
    - Amarillo Heart Clinical Research Institute
  - El Paso, Texas, United States, 79902
    - Med Research, Inc.
  - El Paso, Texas, United States, 79905
    - Texas Tech University Health Sciences Center-El Paso
  - Fort Worth, Texas, United States, 76104
    - Baylor Scott and White Research Institute 1
  - Houston, Texas, United States, 77002
    - East Texas Cardiology, PA
  - Houston, Texas, United States, 77027
    - Physician Research Network
  - Humble, Texas, United States, 77338
    - Vital Heart and Vein
  - Kingwood, Texas, United States, 77339
    - Texas Cardiology Research Center
  - Kyle, Texas, United States, 78640
    - Ascension Texas Cardiovascular
  - Sherman, Texas, United States, 75090
    - Cardiovoyage
  - Tomball, Texas, United States, 77375
    - Northwest Heart Clinical Research, LLC.
- Virginia
  - Falls Church, Virginia, United States, 22042
    - Virginia Heart
  - Newport News, Virginia, United States, 23601
    - Riverside Regional Medical Center
  - Norfolk, Virginia, United States, 23507
    - Sentara Cardiovascular Research Institute
  - Winchester, Virginia, United States, 22601
    - Winchester Medical Center
- Washington
  - Everett, Washington, United States, 98201
    - Providence Regional Medical Center Everett
  - Tacoma, Washington, United States, 98405
    - MultiCare Health System
  - Tacoma, Washington, United States, 98405
    - Cardiac Surgery Group
- Wisconsin
  - La Crosse, Wisconsin, United States, 54601-4795
    - Mayo Clinic Health System
  - Marshfield, Wisconsin, United States, 54449
    - Marshfield Clinic
Vietnam
- - Hanoi, Vietnam, 100000
    - Bach Mai Hospital
  - Hanoi, Vietnam
    - 103 Military Hospital
  - Hanoi, Vietnam
    - Hanoi Medical University Hospital
  - Hanoi, Vietnam
    - Hanoi Heart Hospital
  - Hanoi, Vietnam, 100000
    - Tam Anh General Hospital
  - Ho Chi Minh City, Vietnam, 700000
    - People's Hospital 115
  - Ho Chi Minh City, Vietnam, 700000
    - Thong Nhat HOSPITAL
  - Ho Chi Minh City, Vietnam, 700000
    - Tam Anh Hospital
  - Ho Chi Minh City, Vietnam
    - Tam Duc Heart Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Description

Inclusion Criteria:

Participants must have an index event that meets all 3 of the following criteria within 7 days prior to randomization: a) clinical syndrome consistent with spontaneous cardiac ischemia, b) diagnosis of acute coronary syndrome (ACS) (that is, ST-elevation myocardial infarction [STEMI], non-STEMI, or unstable angina [UA]), c) cardiac biomarker elevation (example, troponin I, troponin T, creatine kinase-MB [CK-MB]) above the upper limit of normal as determined by the local laboratory
Participants must have at least 2 of the following risk factors:a) age 65 or older, b) diabetes mellitus, c) history of a prior myocardial infarction (MI) (other than index ACS event), d) multivessel coronary artery disease (CAD), e) history of coronary artery bypass graft (CABG) surgery prior to index ACS event, f) history of peripheral artery disease (PAD) or cerebrovascular disease (example, carotid atherosclerosis, intracranial artery stenosis, g) conservative management (that is, no percutaneous intervention [PCI] or CABG after index ACS event), h) Any one or more of the following high-risk angiographic features i) total stent length of greater than (>) 30 millimeters (mm), ii) thrombotic target lesion, iii) bifurcation lesion treated with more than one stent, iv) calcified target lesion treated with atherectomy, v) treatment of obstructive left main or proximal left anterior descending artery for index ACS (or clinical diagnosis of an anterior STEMI)
All female participants of childbearing potential must have a negative highly sensitive serum beta-human chorionic gonadotropin (hCG) or urine test at screening
A female participant must not be pregnant, breastfeeding, or planning to become pregnant until 4 days (5 half-lives) after the last dose of study intervention

Exclusion Criteria:

MI secondary to ischemia due to either increased oxygen demand or decreased supply (Type 2 MI) or periprocedural MI as the index ACS event
Planned CABG or staged PCI after randomization
Any condition that requires chronic anticoagulation at the discretion of the investigator and/or local guidelines
Conditions with a significant increased risk of bleeding (example, clinically significant bleeding within previous 3 months, known bleeding diathesis, et cetera)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Quadruple

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Milvexian Participants enrolled within 7 days of an acute coronary syndrome (ACS), who have undergone cardiac catheterization with percutaneous intervention (PCI) or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (single antiplatelet therapy [SAPT] or dual antiplatelet therapy [DAPT]) as determined by the investigator will receive milvexian 25 milligrams (mg), orally, twice daily.	Drug: Milvexian Milvexian will be administered orally. Other Names: BMS-986177 JNJ-70033093
Placebo Comparator: Placebo Participants enrolled within 7 days of an ACS, who have undergone cardiac catheterization with PCI or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (SAPT or DAPT) as determined by the investigator will receive placebo orally, twice daily.	Other: Placebo Placebo will be administered orally.

Participant Group / Arm

Intervention / Treatment

Experimental: Milvexian

Participants enrolled within 7 days of an acute coronary syndrome (ACS), who have undergone cardiac catheterization with percutaneous intervention (PCI) or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (single antiplatelet therapy [SAPT] or dual antiplatelet therapy [DAPT]) as determined by the investigator will receive milvexian 25 milligrams (mg), orally, twice daily.

Drug: Milvexian

Milvexian will be administered orally.

Other Names:

BMS-986177
JNJ-70033093

Placebo Comparator: Placebo

Participants enrolled within 7 days of an ACS, who have undergone cardiac catheterization with PCI or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (SAPT or DAPT) as determined by the investigator will receive placebo orally, twice daily.

Other: Placebo

Placebo will be administered orally.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to First Occurrence of Major Adverse Cardiovascular Event (MACE) Time Frame: Up to 3 years 6 months	Time to first occurrence of any component of MACE will be reported. MACE is a composite of cardiovascular (CV) death, myocardial infarction (MI), and ischemic stroke.	Up to 3 years 6 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to the First Occurrence of Major Adverse Vascular Event (MAVE) Time Frame: Up to 3 years 6 months	Time to first occurrence of any component of MAVE will be reported. MAVE is a composite of CV death, MI, ischemic stroke, major adverse limb event (MALE), and symptomatic venous thromboembolism (VTE).	Up to 3 years 6 months
Time to the First Occurrence of Composite of All-cause Mortality (ACM), Myocardial Infarction (MI) and Ischemic Stroke Time Frame: Up to 3 years 6 months	Time to the first occurrence of composite of ACM, MI and ischemic stroke will be reported.	Up to 3 years 6 months
Time to Cardiovascular (CV) Death Time Frame: Up to 3 years 6 months	Time to CV death will be reported.	Up to 3 years 6 months
Time to All-cause Mortality (ACM) Time Frame: Up to 3 years 6 months	Time to ACM will reported. ACM will be categorized into CV death, non-CV death, and death due to unknown cause.	Up to 3 years 6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Janssen Research & Development, LLC

Collaborators

Bristol-Myers Squibb

Investigators

Study Director: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Gibson CM, Bahit MC, Mehran R, Mehta SR, Lamee RA, Goto S, Weitz JI, Horrow J, Barnathan ES, Harrington RA, Mahaffey KW, Lam CSP, Pieper KS, Johnston SC, Hankey GJ, Plotnikov AN, Li D, Deng H, Steg PG; Librexia ACS Committees and Investigators.. Oral factor xia inhibitor milvexian after a recent acute coronary syndrome: Rationale and design of the phase 3 (Librexia ACS). Am Heart J. 2025 Jul;285:21-28. doi: 10.1016/j.ahj.2025.02.011. Epub 2025 Feb 20.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 7, 2023

Primary Completion (Actual)

February 6, 2026

Study Completion (Actual)

February 6, 2026

Study Registration Dates

First Submitted

February 23, 2023

First Submitted That Met QC Criteria

February 23, 2023

First Posted (Actual)

March 6, 2023

Study Record Updates

Last Update Posted (Actual)

April 13, 2026

Last Update Submitted That Met QC Criteria

April 9, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

CR109271
70033093ACS3003 (Other Identifier: Janssen Research & Development, LLC)
2022-501418-69-00 (Registry Identifier: EUCT number)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

The data sharing policy of the Janssen Pharmaceutical Companies of Johnson & Johnson is available at www.janssen.com/clinical-trials/transparency. As noted on this site, requests for access to the study data can be submitted through Yale Open Data Access (YODA) Project site at yoda.yale.edu

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Study Overview

Status

Conditions

Intervention / Treatment

Study Type

Enrollment (Actual)

Phase

Contacts and Locations

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Description

Study Plan

How is the study designed?

Design Details

Number of Arms

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Collaborators and Investigators

Sponsor

Collaborators

Investigators

Publications and helpful links

General Publications

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Actual)

Study Completion (Actual)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Actual)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

IPD Plan Description

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product

Clinical Trials on Acute Coronary Syndrome

Clinical Trials on Milvexian

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