Effect of HIIT Vs Moderate Intensity Aerobic Exercise on Insulin Resistance in Type 2 DM

October 25, 2023 updated by: Mina Atef Georgui Elias, Badr University

Effect of High Intensity Interval Training Versus Moderate Intensity Aerobic Exercise on Insulin Resistance in Type 2 Diabetes

Comparing between the efficacy of high intensity interval training and moderate intensity aerobic exercises on insulin resistance in type 2 Diabetes Mellitus.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The study aims at differentiating between high intensity interval training and moderate intensity continuous aerobic exercise in terms of their effect of Insulin resistance in patients diagnosed with type 2 Diabetes Mellitus. All participants will have lab analysis for Serum Homa-IR prior to intervention and after 1 month of treatment.

Study Type

Interventional

Enrollment (Actual)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Cairo, Egypt, 11662
        • Ahmed Maher Teaching Hospital
      • Cairo, Egypt, 11725
        • Elamahaba Specialized Charity Polyclinics
      • Cairo, Egypt, 11771
        • Trust Physical Therapy Center and Rehabilitation
      • Cairo, Egypt, 11829
        • Badr University in Cairo, Faculty of Physical Therapy, Outpatient Clinic

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Type 2 Diabetes Mellitus Patients.
  • Diagnosed for more than 1 years at the time of the study.
  • Patients with fair control of blood glucose using hypoglycemic drugs

Exclusion Criteria:

  • Type 1 (Insulin Dependant) Diabetes Mellitus patients.
  • Patients with disability that can't perform exercises.
  • Patient with known Cardiovascular diseases.
  • Patients with kidney/liver diseases

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: High intensity interval training (group A)
30 Diabetic patients (Type 2 Diabetes Mellitus) will receive high intensity interval training
Other: High intensity interval training
Patients will receive interval training exercise of high intensity. This includes several rounds that alternate between several minutes of high intensity movements to significantly increase the heart rate to at least 80% of one's maximum heart rate, followed by short periods of rest
Experimental: moderate intensity aerobic exercise (group B)
30 Diabetic patients (Type 2 Diabetes Mellitus) will receive moderate intensity aerobic exercise
Other: moderate intensity aerobic exercise
Patients will receive moderate intensity continuous aerobic exercise (walking) for 40 minutes (preceded by 10 minutes warming up and followed by 5 minutes cooling down)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Insulin Resistance (Homa-IR)
Time Frame: 1 month
Serum insulin resistance indicator (Homa-IR)
1 month

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Badr University

Collaborators

Ahmed Maher Teaching Hospital

Investigators

  • Principal Investigator: Mina AG Elias, Dr., Dept of Internal Medicine & geriatric, Faculty of Physical Therapy, Badr University in Cairo, Egypt.
  • Study Chair: Khaled M Mounir, Dr., Dept of Cardiopulmonary & internal medicine rehab, Faculty of Physical Therapy, Galala Univ; Egypt.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 7, 2023

Primary Completion (Actual)

August 31, 2023

Study Completion (Actual)

September 30, 2023

Study Registration Dates

First Submitted

June 3, 2023

First Submitted That Met QC Criteria

June 3, 2023

First Posted (Actual)

June 15, 2023

Study Record Updates

Last Update Posted (Actual)

October 27, 2023

Last Update Submitted That Met QC Criteria

October 25, 2023

Last Verified

October 1, 2023

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • BUC-IACUC-230507-21

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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