Effect of Life Kinetik Training on Lower Limb Coordination in Ataxic Patients

August 18, 2023 updated by: heba ahmed khalifa, Cairo University
Coordination is essential for the performance of most daily motor activities. Coordination problems are common in MS patients. One of the most commonly reported symptoms is dysmetria (limb ataxia). Ataxia is thought to occur in about 80% of MS patients. It leads to limitations in daily life activities. Aim of Study: to investigate the effect of life kinetik training on lower limb coordination in MS patients with ataxia.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Methods: Thirty remitting relapsing Multiple Sclerosis (RRMS) patients from both sexes with ataxic symptoms, will be recruited from multiple sclerosis specialized clinic in the Neurology department, Faculty of Medicine, Cairo University with EDSS score will be ranged from 2 to 4 and SARA score will be ranged from 1 to 10. Lower Extremity Motor Coordination Test (LEMOCOT) will be used to assess lower limb motor coordination. They will be randomly assigned into two equal groups; control group (GI) will receive selected physical therapy program and study group (GII) will receive same program of (GI) in addition to life kinetik training.

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Giza, Egypt, 11432
        • Faculty of Physical Therapy

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • MS from both sexes
  • Patients' age will be ranged from 20 to 45 years
  • Expanded disability scale (EDSS) score ranging from "two" to "four"

Exclusion Criteria:

  • Patients with Ataxia caused by other cause rather than MS
  • Patients with other neurological disease or orthopedic deformities may affect movement
  • Patients with cardiovascular and pulmonary diseases that make exercise unsafe
  • Patients with cognitive impairment or psychiatric disorders

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: study group
will receive physical therapy program of in addition to life kinetik training.
Other: physical therapy
Frenkel's exercises for lower limb, Proprioceptive neuromuscular facilitation for upper limb in the form of rhythmic stabilization
Other: life kinetic exercises
A multimodal training that combines coordinative, cognitive and visual tasks.
Active Comparator: control
will receive physical therapy program
Other: physical therapy
Frenkel's exercises for lower limb, Proprioceptive neuromuscular facilitation for upper limb in the form of rhythmic stabilization

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Lower Extremity Motor Coordination Test (LEMOCOT)
Time Frame: at baseline
test to assess lower limb coordination
at baseline
Lower Extremity Motor Coordination Test (LEMOCOT)
Time Frame: post intervention (after one month)
test to assess lower limb coordination
post intervention (after one month)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Four Square Step Test (FSST)
Time Frame: at baseline
test to assess dynamic balance
at baseline
Four Square Step Test (FSST)
Time Frame: post intervention (after one month)
test to assess dynamic balance
post intervention (after one month)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Investigators

  • Study Director: Moshera H Darwish, Prf. Dr, Professor of Physical therapy for Neurology

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 24, 2018

Primary Completion (Actual)

April 30, 2021

Study Completion (Actual)

May 29, 2021

Study Registration Dates

First Submitted

January 17, 2021

First Submitted That Met QC Criteria

August 18, 2023

First Posted (Actual)

August 21, 2023

Study Record Updates

Last Update Posted (Actual)

August 21, 2023

Last Update Submitted That Met QC Criteria

August 18, 2023

Last Verified

August 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • P.T.REC/012/001987

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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