A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

May 27, 2026 updated by: Merck Sharp & Dohme LLC

A Phase 3, Open-label Study of Ifinatamab Deruxtecan Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (IDeate-Prostate01)

Researchers are looking for new ways to treat metastatic castration-resistant prostate cancer (mCRPC). Researchers have designed a study medicine called ifinatamab deruxtecan (also called I-DXd or MK-2400) to treat mCRPC. The goal of this study is to learn if people who receive I-DXd live longer overall and live longer without the cancer growing or spreading than people who receive chemotherapy.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

1440

Phase

  • Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Argentina
      • CABA, Argentina, C1426ABP
        • Recruiting
        • Centro Medico Dra De Salvo ( Site 0132)
        • Contact:
          • Study Coordinator
          • Phone Number: +5491151082017
      • La Rioja, Argentina, F5300COE
        • Recruiting
        • Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0131)
        • Contact:
          • Study Coordinator
          • Phone Number: +543804693919
      • Mendoza, Argentina, M5500AYB
        • Recruiting
        • Centro Oncologico de Integracion Regional. COIR ( Site 0130)
        • Contact:
          • Study Coordinator
          • Phone Number: +542614252575
      • Salta, Argentina, A4400AWG
        • Recruiting
        • Centro de Diagnostico Investigación y Tratamiento Oncológico (CeDIT) ( Site 0135)
        • Contact:
          • Study Coordinator
          • Phone Number: +5403874227282
      • San Juan, Argentina, J5400EBB
        • Recruiting
        • Instituto San Marcos ( Site 0137)
        • Contact:
          • Study Coordinator
          • Phone Number: +5492645836798
    • Buenos Aires
      • Berazategui, Buenos Aires, Argentina, B1884BBF
        • Recruiting
        • Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 0136)
        • Contact:
          • Study Coordinator
          • Phone Number: +541142262013
      • Mar del Plata, Buenos Aires, Argentina, B7600FZO
        • Recruiting
        • Instituto de Investigaciones Clinicas Mar del Plata ( Site 0129)
        • Contact:
          • Study Coordinator
          • Phone Number: +5491132661847
      • Mar del Plata, Buenos Aires, Argentina, C1426ANZ
        • Recruiting
        • Instituto Alexander Fleming ( Site 0125)
        • Contact:
          • Study Coordinator
          • Phone Number: +541132218900
    • Santa Fe Province
      • Rosario, Santa Fe Province, Argentina, S2000DSV
        • Recruiting
        • Sanatorio Parque ( Site 0126)
        • Contact:
          • Study Coordinator
          • Phone Number: +543414200222
  • Australia
    • New South Wales
      • Blacktown, New South Wales, Australia, 2148
        • Recruiting
        • Blacktown Hospital ( Site 0154)
        • Contact:
          • Study Coordinator
          • Phone Number: 61298818000
      • Macquarie University, New South Wales, Australia, 2109
        • Recruiting
        • Macquarie University-MQ Health Clinical Trials Unit ( Site 0151)
        • Contact:
          • Study Coordinator
          • Phone Number: +61 2 9812 2956
    • Queensland
      • Greenslopes, Queensland, Australia, 4120
        • Recruiting
        • Gallipoli Medical Research Ltd ( Site 0153)
        • Contact:
          • Study Coordinator
          • Phone Number: +61402240196
    • Victoria
      • Melbourne, Victoria, Australia, 3000
        • Recruiting
        • Peter MacCallum Cancer Centre ( Site 0152)
        • Contact:
          • Study Coordinator
          • Phone Number: +61385595000
    • Western Australia
      • Murdock, Western Australia, Australia, 6150
        • Recruiting
        • Fiona Stanley Hospital ( Site 0155)
        • Contact:
          • Study Coordinator
          • Phone Number: +61861525886
  • Austria
      • Salzburg, Austria, 5020
        • Recruiting
        • Uniklinikum Salzburg Universitaetsklinik für Innere Medizin III ( Site 0172)
        • Contact:
          • Study Coordinator
          • Phone Number: +435725558858
    • Upper Austria
      • Linz, Upper Austria, Austria, 4020
        • Recruiting
        • Ordensklinikum Linz GmbH Elisabethinen-Urologie ( Site 0170)
        • Contact:
          • Study Coordinator
          • Phone Number: +4373276774724
      • Wels, Upper Austria, Austria, 4600
        • Recruiting
        • Klinikum Wels-Grieskirchen GmbH ( Site 0171)
        • Contact:
          • Study Coordinator
          • Phone Number: +4372424153452
  • Brazil
      • São Paulo, Brazil, 01221-020
        • Recruiting
        • IPITEC ( Site 0189)
        • Contact:
          • Study Coordinator
          • Phone Number: +55 14 99776-3115
      • São Paulo, Brazil, 04014-012
        • Recruiting
        • IBCC - Núcleo de Pesquisa e Ensino ( Site 0183)
        • Contact:
          • Study Coordinator
          • Phone Number: +551144500300
    • Minas Gerais
      • Belo Horizonte, Minas Gerais, Brazil, 30380-472
        • Recruiting
        • Hospital Mario Penna ( Site 0179)
        • Contact:
          • Study Coordinator
          • Phone Number: +55 31 98803-2851
    • Paraná
      • Curitiba, Paraná, Brazil, 80730-150
        • Recruiting
        • Hospital Universitário Evangélico Mackenzie ( Site 0181)
        • Contact:
          • Study Coordinator
          • Phone Number: +5541991681411
    • Rio Grande do Sul
      • Porto Alegre, Rio Grande do Sul, Brazil, 90020-090
        • Recruiting
        • Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0184)
        • Contact:
          • Study Coordinator
          • Phone Number: +55 51 32148107
    • São Paulo
      • São José do Rio Preto, São Paulo, Brazil, 15090-000
        • Recruiting
        • Hospital de Base de São José do Rio Preto ( Site 0176)
        • Contact:
          • Study Coordinator
          • Phone Number: +5517988053335
  • Chile
    • Region M. de Santiago
      • Santiago, Region M. de Santiago, Chile, 8420383
        • Recruiting
        • Bradfordhill ( Site 0200)
        • Contact:
          • Study Coordinator
          • Phone Number: +56229490970
      • Santiago, Region M. de Santiago, Chile, 7500921
        • Recruiting
        • FALP ( Site 0201)
        • Contact:
          • Study Coordinator
          • Phone Number: 56224457398
  • China
    • Beijing Municipality
      • Beijing, Beijing Municipality, China, 100034
        • Recruiting
        • Peking University First Hospital ( Site 1434)
        • Contact:
          • Study Coordinator
          • Phone Number: 010-83572505
      • Beijing, Beijing Municipality, China, 200080
        • Recruiting
        • Shanghai General Hospital ( Site 1449)
        • Contact:
          • Study Coordinator
          • Phone Number: 021-36126255
    • Chongqing Municipality
      • Chongqing, Chongqing Municipality, China, 400016
        • Recruiting
        • The First Affiliated Hospital of Chonqing Medical University ( Site 1406)
        • Contact:
          • Study Coordinator
          • Phone Number: 02389012012
      • Chongqing, Chongqing Municipality, China, 404199
        • Recruiting
        • Chongqing University Three Gorges Hospital ( Site 1405)
        • Contact:
          • Study Coordinator
          • Phone Number: 02358104650
    • Fujian
      • Fuzhou, Fujian, China, 350005
        • Recruiting
        • The First Affiliated Hospital Of Fujian Medical University ( Site 1452)
        • Contact:
          • Study Coordinator
          • Phone Number: 0591-87981262
    • Guangdong
      • Guangzhou, Guangdong, China, 510000
        • Recruiting
        • Guangzhou First People's Hospital ( Site 1410)
        • Contact:
          • Study Coordinator
          • Phone Number: 020-81048888
      • Guangzhou, Guangdong, China, 510060
        • Recruiting
        • Sun Yat-Sen University Cancer Center ( Site 1467)
        • Contact:
          • Study Coordinator
          • Phone Number: 020-87343565
      • Guangzhou, Guangdong, China, 510220
        • Recruiting
        • Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1402)
        • Contact:
          • Study Coordinator
          • Phone Number: 020-81332199
      • Guangzhou, Guangdong, China, 510300
        • Recruiting
        • Sun Yat-sen University Cancer Center ( Site 1409)
        • Contact:
          • Study Coordinator
          • Phone Number: +862066673666
      • Zhuhai, Guangdong, China, 51900
        • Recruiting
        • The Fifth Affiliated Hospital of Sun Yat-Sen University ( Site 1459)
        • Contact:
          • Study Coordinator
          • Phone Number: +8607562528188
    • Guangxi
      • Nanning, Guangxi, China, 530201
        • Recruiting
        • Guangxi Medical University Cancer Hospital ( Site 1414)
        • Contact:
          • Study Coordinator
          • Phone Number: 0771-5331955
    • Henan
      • Zhengzhou, Henan, China, 450008
        • Recruiting
        • Henan Cancer Hospital ( Site 1472)
        • Contact:
          • Study Coordinator
          • Phone Number: 400-0371-818
    • Hubei
      • Wuhan, Hubei, China, 430022
        • Recruiting
        • Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 1424)
        • Contact:
          • Study Coordinator
          • Phone Number: 027-85726114
    • Hunan
      • Changsha, Hunan, China, 410013
        • Recruiting
        • Hunan Cancer Hospital ( Site 1411)
        • Contact:
          • Study Coordinator
          • Phone Number: 0731-89762271
    • Jiangsu
      • Nanjing, Jiangsu, China, 210008
        • Recruiting
        • Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School ( Site 1425)
        • Contact:
          • Study Coordinator
          • Phone Number: 02583106666
      • Nanjing, Jiangsu, China, 210029
        • Recruiting
        • Jiangsu Province Hospital ( Site 1426)
        • Contact:
          • Study Coordinator
          • Phone Number: 025-68306259
      • Nanjing, Jiangsu, China, 214023
        • Recruiting
        • Zhongda Hospital Southeast University ( Site 1427)
        • Contact:
          • Study Coordinator
          • Phone Number: 025-83272084
      • Xuzhou, Jiangsu, China, 221002
        • Recruiting
        • The Affiliated Hospital of Xuzhou Medical University ( Site 1438)
        • Contact:
          • Study Coordinator
          • Phone Number: 0516-85806507
    • Jilin
      • Changchun, Jilin, China, 130021
        • Recruiting
        • Jilin Province People's Hospital ( Site 1461)
        • Contact:
          • Study Coordinator
          • Phone Number: 0431-8595238
    • Shaanxi
      • Xi'an, Shaanxi, China, 710061
        • Recruiting
        • The first affiliated Hospital of Xi an Jiaotong University ( Site 1408)
        • Contact:
          • Study Coordinator
          • Phone Number: 029-85323112
    • Shandong
      • Jinan, Shandong, China, 250117
        • Recruiting
        • Shandong Cancer Hospital ( Site 1421)
        • Contact:
          • Study Coordinator
          • Phone Number: 0531-67626986
    • Shanghai Municipality
      • Shanghai, Shanghai Municipality, China, 200000
        • Recruiting
        • Shanghai Tenth People's Hospital ( Site 1441)
        • Contact:
          • Study Coordinator
          • Phone Number: 021-66300588
      • Shanghai, Shanghai Municipality, China, 200032
        • Recruiting
        • Fudan University Shanghai Cancer Center ( Site 1400)
        • Contact:
          • Study Coordinator
          • Phone Number: 021-64175590
      • Shanghai, Shanghai Municipality, China, 200032
        • Recruiting
        • Zhongshan Hospital Fudan University ( Site 1430)
        • Contact:
          • Study Coordinator
          • Phone Number: 8602131587861
      • Shanghai, Shanghai Municipality, China, 200065
        • Recruiting
        • Shanghai Tongji Hospital ( Site 1412)
        • Contact:
          • Study Coordinator
          • Phone Number: 021-56051080
      • Shanghai, Shanghai Municipality, China, 200127
        • Recruiting
        • Renji Hospital Shanghai Jiao Tong University School of Medicine ( Site 1457)
        • Contact:
          • Study Coordinator
          • Phone Number: 021-58752345
    • Shanxi
      • Taiyuan, Shanxi, China, 030001
        • Recruiting
        • First Affiliated Hospital Of Shanxi Medical University ( Site 1460)
        • Contact:
          • Study Coordinator
          • Phone Number: +86 0351-4639766
    • Sichuan
      • Chengdu, Sichuan, China, 610041
        • Recruiting
        • West China Hospital of Sichuan University ( Site 1451)
        • Contact:
          • Study Coordinator
          • Phone Number: +8618980606710
      • Chengdu, Sichuan, China, 610041
        • Recruiting
        • West China Hospital, Sichuan University ( Site 1468)
        • Contact:
          • Study Coordinator
          • Phone Number: 028-85422114
    • Xinjiang
      • Ürümqi, Xinjiang, China, 830000
        • Recruiting
        • The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 1469)
        • Contact:
          • Study Coordinator
          • Phone Number: 0991-7968088
    • Zhejiang
      • Hangzhou, Zhejiang, China, 310022
        • Recruiting
        • Zhejiang Cancer Hospital ( Site 1447)
        • Contact:
          • Study Coordinator
          • Phone Number: 0571-88122222
      • Jiaxing, Zhejiang, China, 314001
        • Recruiting
        • The First Hospital of Jiaxing ( Site 1416)
        • Contact:
          • Study Coordinator
          • Phone Number: 0573-82519999
      • Ningbo, Zhejiang, China, 315010
        • Recruiting
        • The First Affiliated Hospital of Ningbo University ( Site 1419)
        • Contact:
          • Study Coordinator
          • Phone Number: 86057487085146
      • Wenzhou, Zhejiang, China, 325000
        • Recruiting
        • The First Affiliated Hospital of Wenzhou Medical University ( Site 1437)
        • Contact:
          • Study Coordinator
          • Phone Number: 057755579999
  • Colombia
    • Antioquia
      • Medellín, Antioquia, Colombia, 050025
        • Recruiting
        • Instituto de Cancerología S.A.S ( Site 0234)
        • Contact:
          • Study Coordinator
          • Phone Number: +576043421010
    • Atlántico
      • Barranquilla, Atlántico, Colombia, 080002
        • Recruiting
        • Centro Cancerológico del Caribe (CECAC) ( Site 0227)
        • Contact:
          • Study Coordinator
          • Phone Number: +573003263183
    • Bogota D.C.
      • Bogotá, Bogota D.C., Colombia, 111321
        • Recruiting
        • Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 0229)
        • Contact:
          • Study Coordinator
          • Phone Number: +57 3103469453
      • Bogotá, Bogota D.C., Colombia, 111511
        • Recruiting
        • Instituto Nacional De Cancerologia ( Site 0237)
        • Contact:
          • Study Coordinator
          • Phone Number: +57 311 8083188
    • Cesar Department
      • Valledupar, Cesar Department, Colombia, 200001
        • Recruiting
        • Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 0228)
        • Contact:
          • Study Coordinator
          • Phone Number: +57 315 8505190
    • Cundinamarca
      • Bogota, Cundinamarca, Colombia, 110111
        • Recruiting
        • FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0230)
        • Contact:
          • Study Coordinator
          • Phone Number: +57 3219198898
    • Risaralda Department
      • Pereira, Risaralda Department, Colombia, 660001
        • Recruiting
        • Oncologos Del Occidente ( Site 0231)
        • Contact:
          • Study Coordinator
          • Phone Number: +576063310712
  • Czechia
      • Olomouc, Czechia, 779 00
        • Recruiting
        • Fakultni nemocnice Olomouc ( Site 0262)
        • Contact:
          • Study Coordinator
          • Phone Number: +420585851111
    • Brno-mesto
      • Brno, Brno-mesto, Czechia, 656 53
        • Recruiting
        • Masarykuv onkologicky ustav ( Site 0260)
        • Contact:
          • Study Coordinator
          • Phone Number: +420543131111
      • Brno, Brno-mesto, Czechia, 602 00
        • Recruiting
        • Fakultni nemocnice u sv. Anny v Brne ( Site 0264)
        • Contact:
          • Study Coordinator
          • Phone Number: +420543182181
    • Moravian-Silesian Region
      • Ostrava - Poruba, Moravian-Silesian Region, Czechia, 708 52
        • Recruiting
        • Fakultni nemocnice Ostrava ( Site 0263)
        • Contact:
          • Study Coordinator
          • Phone Number: +420597371111
    • Praha 5
      • Prague, Praha 5, Czechia, 150 06
        • Recruiting
        • Fakultni Nemocnice v Motole ( Site 0261)
        • Contact:
          • Study Coordinator
          • Phone Number: +420224431111
  • Denmark
    • Capital Region
      • Herlev, Capital Region, Denmark, 2370
        • Recruiting
        • Herlev and Gentofte Hospital ( Site 0290)
        • Contact:
          • Study Coordinator
          • Phone Number: +4538683868
    • North Denmark
      • Aalborg, North Denmark, Denmark, 9000
        • Recruiting
        • Aalborg Universitetshospital, Syd ( Site 0293)
        • Contact:
          • Study Coordinator
          • Phone Number: 97661400
    • Region Syddanmark
      • Odense, Region Syddanmark, Denmark, 5000
        • Recruiting
        • Odense Universitetshospital ( Site 0294)
        • Contact:
          • Study Coordinator
          • Phone Number: +4566113333
      • Vejle, Region Syddanmark, Denmark, 7100
        • Recruiting
        • Vejle Sygehus ( Site 0291)
        • Contact:
          • Study Coordinator
          • Phone Number: 79406060
  • France
    • Ain
      • Suresnes, Ain, France, 92150
        • Recruiting
        • Hôpital Foch ( Site 0309)
        • Contact:
          • Study Coordinator
          • Phone Number: +33146253581
    • Bouches-du-Rhone
      • Marseille, Bouches-du-Rhone, France, 13273
        • Recruiting
        • Hôpital Privé Clairval ( Site 0303)
        • Contact:
          • Study Coordinator
          • Phone Number: +33496196230
    • Calvados
      • Caen, Calvados, France, 14076
        • Recruiting
        • Centre François Baclesse ( Site 0311)
        • Contact:
          • Study Coordinator
          • Phone Number: +33231455002
    • Doubs
      • Besançon, Doubs, France, 25000
        • Completed
        • CHU Besançon ( Site 0305)
    • Gard
      • Nîmes, Gard, France, 30029
        • Recruiting
        • Centre Hospitalier Universitaire de Nîmes - Institut de Canc-Medical Oncology ( Site 0313)
        • Contact:
          • Study Coordinator
          • Phone Number: +330466282491
    • Haute-Vienne
      • Limoges, Haute-Vienne, France, 87039
        • Recruiting
        • Clinique Francois Chenieux ( Site 0312)
        • Contact:
          • Study Coordinator
          • Phone Number: +33555454800
    • Meurthe-et-Moselle
      • Vandœuvre-lès-Nancy, Meurthe-et-Moselle, France, 54519
        • Recruiting
        • Institut de Cancérologie de Lorraine Alexis Vautrin ( Site 0307)
        • Contact:
          • Study Coordinator
          • Phone Number: +33383598551
    • Seine-Maritime
      • Rouen, Seine-Maritime, France, 76031
        • Recruiting
        • CHU de Rouen ( Site 0301)
        • Contact:
          • Study Coordinator
          • Phone Number: +33232881315
    • Île-de-France Region
      • Paris, Île-de-France Region, France, 75010
        • Recruiting
        • Hôpital Saint-Louis ( Site 0310)
        • Contact:
          • Study Coordinator
          • Phone Number: +33142494212
  • Germany
      • Berlin, Germany, 10117
        • Recruiting
        • Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0352)
        • Contact:
          • Study Coordinator
          • Phone Number: 4930450615285
      • Hamburg, Germany, 20246
        • Recruiting
        • Universitaetsklinik Hamburg-Eppendorf ( Site 0351)
        • Contact:
          • Study Coordinator
          • Phone Number: +4915222815585
    • Baden-Wurttemberg
      • Nürtingen, Baden-Wurttemberg, Germany, 72622
        • Recruiting
        • Studienpraxis Urologie ( Site 0358)
        • Contact:
          • Study Coordinator
          • Phone Number: 0049 15201622246
      • Stuttgart, Baden-Wurttemberg, Germany, 70174
        • Recruiting
        • Klinikum Stuttgart - Katharinenhospital ( Site 0355)
        • Contact:
          • Study Coordinator
          • Phone Number: +4971127854720
    • Bavaria
      • Munich, Bavaria, Germany, 81675
        • Recruiting
        • klinikum rechts der isar der technischen universität münchen ( Site 0350)
        • Contact:
          • Study Coordinator
          • Phone Number: 49 89 4140 2522
      • Nuremberg, Bavaria, Germany, 90419
        • Recruiting
        • Klinikum Nuernberg Nord ( Site 0353)
        • Contact:
          • Study Coordinator
          • Phone Number: +49 911 398 3085
    • Hesse
      • Frankfurt am Main, Hesse, Germany, 60590
        • Recruiting
        • Universitätsklinikum Frankfurt Goethe-Universität ( Site 0354)
        • Contact:
          • Study Coordinator
          • Phone Number: +4969630180072
    • North Rhine-Westphalia
      • Duisburg, North Rhine-Westphalia, Germany, 47169
        • Recruiting
        • Urologicum Duisburg ( Site 0361)
        • Contact:
          • Study Coordinator
          • Phone Number: +4920360012919
    • Schleswig-Holstein
      • Lübeck, Schleswig-Holstein, Germany, 23538
        • Recruiting
        • Universitaetsklinikum Schleswig Holstein ( Site 0360)
        • Contact:
          • Study Coordinator
          • Phone Number: +49 451 500 43601
  • Greece
    • Attica
      • Athens, Attica, Greece, 115 26
        • Recruiting
        • Henry Dunant Hospital ( Site 0385)
        • Contact:
          • Study Coordinator
          • Phone Number: +302106972000
      • Athens, Attica, Greece, 155 62
        • Recruiting
        • Metropolitan General Hospital ( Site 0382)
        • Contact:
          • Study Coordinator
          • Phone Number: 0030 2106502831
      • Chaidari Athens, Attica, Greece, 124 62
        • Recruiting
        • University General Hospital Attikon ( Site 0381)
        • Contact:
          • Study Coordinator
          • Phone Number: +302105831000
      • Kifissia, Attica, Greece, 145 64
        • Recruiting
        • General Oncology Hospital of Kifisia "Agioi Anargyroi" ( Site 0384)
        • Contact:
          • Study Coordinator
          • Phone Number: +302103501500
      • Marousi, Attica, Greece, 151 25
        • Recruiting
        • Athens Medical Center ( Site 0383)
        • Contact:
          • Study Coordinator
          • Phone Number: +302106198100
  • Guatemala
      • Guatemala City, Guatemala, 01010
        • Recruiting
        • Onco Go ( Site 0402)
        • Contact:
          • Study Coordinator
          • Phone Number: +502 42140711
      • Guatemala City, Guatemala, 01009
        • Recruiting
        • MEDI-K ( Site 0401)
        • Contact:
          • Study Coordinator
          • Phone Number: +502 22912323
      • Guatemala City, Guatemala, 01010
        • Recruiting
        • Med Clinic ( Site 0403)
        • Contact:
          • Study Coordinator
          • Phone Number: +502 41040976
  • Hong Kong
      • Hong Kong, Hong Kong
        • Recruiting
        • Queen Mary Hospital ( Site 0415)
        • Contact:
          • Study Coordinator
          • Phone Number: +852 2255 3838
      • New Territories, Hong Kong
        • Recruiting
        • Tuen Mun Hospital ( Site 0416)
        • Contact:
          • Study Coordinator
          • Phone Number: +852 2468 5111
  • Ireland
      • Cork, Ireland, T12 E8YV
        • Recruiting
        • Cork University Hospital ( Site 0442)
        • Contact:
          • Study Coordinator
          • Phone Number: +350214922687
      • Dublin, Ireland, D24 NR0A
        • Recruiting
        • Tallaght University Hospital ( Site 0440)
        • Contact:
          • Study Coordinator
          • Phone Number: +35314144299
    • Dublin
      • Dublin, Dublin, Ireland, D04 T6F4
        • Recruiting
        • St Vincent's University Hospital ( Site 0441)
        • Contact:
          • Study Coordinator
          • Phone Number: +4412214000
  • Israel
      • Haifa, Israel, 3109601
        • Recruiting
        • Rambam Health Care Campus ( Site 0462)
        • Contact:
          • Study Coordinator
          • Phone Number: 04-7776234
      • Jerusalem, Israel, 9103102
        • Recruiting
        • Shaare Zedek Medical Center ( Site 0468)
        • Contact:
          • Study Coordinator
          • Phone Number: +97226555999
      • Kfar Saba, Israel, 4428164
        • Recruiting
        • Meir Medical Center ( Site 0464)
        • Contact:
          • Study Coordinator
          • Phone Number: 972-50-3745684
      • Petah Tikva, Israel, 4941492
        • Recruiting
        • Rabin Medical Center ( Site 0461)
        • Contact:
          • Study Coordinator
          • Phone Number: 972-3-9378074
      • Ramat Gan, Israel, 5265601
        • Recruiting
        • Sheba Medical Center ( Site 0460)
        • Contact:
          • Study Coordinator
          • Phone Number: 0544557539
      • Tel Aviv, Israel, 6423906
        • Recruiting
        • Sourasky Medical Center ( Site 0463)
        • Contact:
          • Study Coordinator
          • Phone Number: 03-6974907
      • Ẕerifin, Israel, 7033001
        • Recruiting
        • Yitzhak Shamir Medical Center. ( Site 0466)
        • Contact:
          • Study Coordinator
          • Phone Number: 972-8-9542196
  • Italy
      • Arezzo, Italy, 52100
        • Recruiting
        • Azienda USL 8 di Arezzo ( Site 0503)
        • Contact:
          • Study Coordinator
          • Phone Number: 0575255446
      • Bergamo, Italy, 24125
        • Recruiting
        • Humanitas Gavazzeni ( Site 0508)
        • Contact:
          • Study Coordinator
          • Phone Number: (+39) 0354204663
      • Foggia, Italy, 71122
        • Recruiting
        • Azienda Ospedaliero Universitaria Policlinico Riuniti di Foggia ( Site 0510)
        • Contact:
          • Study Coordinator
          • Phone Number: 0881-736426
      • Terni, Italy, 05100
        • Recruiting
        • Azienda Ospedaliera Santa Maria Terni ( Site 0509)
        • Contact:
          • Study Coordinator
          • Phone Number: (+39) 0744205410
      • Verona, Italy, 37134
        • Recruiting
        • Centro Ricerche Cliniche di Verona ( Site 0506)
        • Contact:
          • Study Coordinator
          • Phone Number: 0458128120
    • Lombardy
      • Milan, Lombardy, Italy, 20133
        • Recruiting
        • Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 0500)
        • Contact:
          • Study Coordinator
          • Phone Number: (+39) 0223903028
    • Milano
      • Rozzano, Milano, Italy, 20089
        • Recruiting
        • Istituto Clinico Humanitas ( Site 0504)
        • Contact:
          • Study Coordinator
          • Phone Number: (+39) 0282244061
    • Roma
      • Rome, Roma, Italy, 00128
        • Recruiting
        • Istituto Nazionale Tumori Regina Elena ( Site 0507)
        • Contact:
          • Study Coordinator
          • Phone Number: +390652666271
    • Tuscany
      • Siena, Tuscany, Italy, 53100
        • Recruiting
        • Azienda Ospedaliero Universitaria Senese ( Site 0505)
        • Contact:
          • Study Coordinator
          • Phone Number: (+39) 0577586335
  • Japan
      • Fukuoka, Japan, 812-0033
        • Recruiting
        • Harasanshin Hospital ( Site 1517)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-92-291-3434
      • Fukuoka, Japan, 812-8582
        • Recruiting
        • Kyushu University Hospital ( Site 1515)
        • Contact:
          • Study Coordinator
          • Phone Number: +81926425774
      • Gifu, Japan, 501-1194
        • Recruiting
        • Gifu University Hospital ( Site 1527)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-58-230-6000
      • Hiroshima, Japan, 734-8551
        • Recruiting
        • Hiroshima University Hospital ( Site 1512)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-82-257-5555
      • Kagoshima, Japan, 890-8520
        • Recruiting
        • Kagoshima University Hospital ( Site 1518)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-99-275-5111
      • Kagoshima, Japan, 890-8760
        • Recruiting
        • Kagoshima City Hospital ( Site 1528)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-99-230-7000
      • Kumamoto, Japan, 860-0008
        • Recruiting
        • National Hospital Organization Kumamoto Medical Center ( Site 1524)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-96-353-6501
      • Kyoto, Japan, 602-8566
        • Recruiting
        • University Hospital,Kyoto Prefectural University of Medicine ( Site 1525)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-75-251-5111
      • Nagano, Japan, 381-8551
        • Recruiting
        • Nagano Municipal Hospital ( Site 1526)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-26-295-1199
      • Nagasaki, Japan, 852-8501
        • Recruiting
        • Nagasaki University Hospital ( Site 1523)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-958-19-7200
      • Niigata, Japan, 951-8566
        • Recruiting
        • Niigata Cancer Center Hospital ( Site 1529)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-25-266-5111
      • Tokushima, Japan, 770-8503
        • Recruiting
        • Tokushima University Hospital ( Site 1513)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-88-633-9294
    • Aichi-ken
      • Nagoya, Aichi-ken, Japan, 466-8560
        • Recruiting
        • Nagoya University Hospital ( Site 1508)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-52-741-2111
    • Chiba
      • Sakura, Chiba, Japan, 285-8741
        • Recruiting
        • Toho University Sakura Medical Center ( Site 1503)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-43-462-8811
    • Ehime
      • Tōon, Ehime, Japan, 791-0295
        • Recruiting
        • Ehime University Hospital ( Site 1514)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-89-964-5111
    • Fukuoka
      • Kitakyushu, Fukuoka, Japan, 807-8556
        • Recruiting
        • Hospital of the University of Occupational and Environmental Health, Japan ( Site 1510)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-93-691-7503
      • Kurume, Fukuoka, Japan, 830-0011
        • Recruiting
        • Kurume University Hospital ( Site 1516)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-942-35-3311
    • Hokkaido
      • Sapporo, Hokkaido, Japan, 060-8648
        • Recruiting
        • Hokkaido University Hospital ( Site 1500)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-11-716-1161
      • Sapporo, Hokkaido, Japan, 060-8543
        • Recruiting
        • Sapporo Medical University Hospital ( Site 1501)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-11-611-2111
    • Hyōgo
      • Kobe, Hyōgo, Japan, 650-0017
        • Recruiting
        • Kobe University Hospital ( Site 1511)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-78-382-5111
    • Ishikawa-ken
      • Kahoku-gun, Ishikawa-ken, Japan, 920-0293
        • Recruiting
        • Kanazawa Medical University Hospital ( Site 1507)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-76-286-3511
    • Kanagawa
      • Kamakura, Kanagawa, Japan, 247-8533
        • Recruiting
        • Shonan Kamakura General Hospital ( Site 1530)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-467-46-1717
    • Oita Prefecture
      • Yufu, Oita Prefecture, Japan, 879-5593
        • Recruiting
        • Oita University Hospital ( Site 1521)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-97-549-4411
    • Okinawa
      • Ginowan, Okinawa, Japan, 901-2725
        • Recruiting
        • University of the Ryukyus Hospital ( Site 1519)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-98-894-1455
    • Osaka
      • Sakai, Osaka, Japan, 599-8247
        • Recruiting
        • Bell Land General Hospital ( Site 1509)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-72-234-2001
    • Saitama
      • Koshigaya, Saitama, Japan, 343-8555
        • Recruiting
        • Dokkyo Medical University Saitama Medical Center ( Site 1502)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-48-965-1111
    • Shizuoka
      • Hamamatsu, Shizuoka, Japan, 431-3192
        • Recruiting
        • Hamamatsu University Hospital ( Site 1520)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-53-435-2111
    • Tokyo
      • Minato, Tokyo, Japan, 105-8471
        • Recruiting
        • The Jikei University Hospital ( Site 1504)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-3-3433-1111
      • Shinjuku, Tokyo, Japan, 162-8666
        • Active, not recruiting
        • Tokyo Women's Medical University ( Site 1505)
    • Yamaguchi
      • Ube, Yamaguchi, Japan, 755-8505
        • Recruiting
        • Yamaguchi University Hospital ( Site 1522)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-836-22-2111
    • Yamanashi
      • Chūō, Yamanashi, Japan, 409-3898
        • Recruiting
        • University of Yamanashi Hospital ( Site 1506)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-55-273-9325
  • Malaysia
    • Sarawak
      • Kuching, Sarawak, Malaysia, 93586
        • Recruiting
        • Sarawak General Hospital ( Site 0526)
        • Contact:
          • Study Coordinator
          • Phone Number: +6082276666
    • Selangor
      • Petaling Jaya, Selangor, Malaysia, 47500
        • Recruiting
        • Sunway Medical Centre ( Site 0529)
        • Contact:
          • Study Coordinator
          • Phone Number: +60374919191
  • Mexico
    • Hidalgo
      • Pachuca, Hidalgo, Mexico, 42000
        • Recruiting
        • Grupo Ollin Care ( Site 0544)
        • Contact:
          • Study Coordinator
          • Phone Number: +52771715 752
    • Jalisco
      • Guadalajara, Jalisco, Mexico, 44630
        • Recruiting
        • CIO - Centro de Inmuno-Oncología de Occidente ( Site 0541)
        • Contact:
          • Study Coordinator
          • Phone Number: +52 3313587270
    • Mexico City
      • Mexico City, Mexico City, Mexico, 14080
        • Recruiting
        • Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran ( Site 0545)
        • Contact:
          • Study Coordinator
          • Phone Number: +52 5554870900 2255
      • Mexico City, Mexico City, Mexico, 11810
        • Recruiting
        • Higiea Oncologia ( Site 0542)
        • Contact:
          • Study Coordinator
          • Phone Number: 55 5273 1712
    • Nuevo León
      • Monterrey, Nuevo León, Mexico, 64460
        • Recruiting
        • Hospital Universitario "Dr. Jose Eleuterio Gonzalez" ( Site 0540)
        • Contact:
          • Study Coordinator
          • Phone Number: 81 83338111 ext 1100
    • Oaxaca
      • Oaxaca City, Oaxaca, Mexico, 68020
        • Recruiting
        • Centro de Investigacion Clinica de Oaxaca ( Site 0543)
        • Contact:
          • Study Coordinator
          • Phone Number: 9516035559
  • Netherlands
      • Groningen, Netherlands, 9728 NT
        • Recruiting
        • Martini Ziekenhuis ( Site 0621)
        • Contact:
          • Study Coordinator
          • Phone Number: 050-5246311
      • Utrecht, Netherlands, 3543 AZ
        • Recruiting
        • St. Antonius Ziekenhuis, locatie Utrecht ( Site 0620)
        • Contact:
          • Study Coordinator
          • Phone Number: +31883205148
    • Gelderland
      • Nijmegen, Gelderland, Netherlands, 6525 GA
        • Recruiting
        • UMC St. Radboud ( Site 0601)
        • Contact:
          • Study Coordinator
          • Phone Number: 0031243610353
    • Limburg
      • Maastricht, Limburg, Netherlands, 6229 HX
        • Recruiting
        • Maastricht UMC+ ( Site 0612)
        • Contact:
          • Study Coordinator
          • Phone Number: 043-3877025
      • Venlo, Limburg, Netherlands, 5912 BL
        • Recruiting
        • VieCuri Medisch Centrum, locatie Venlo ( Site 0610)
        • Contact:
          • Study Coordinator
          • Phone Number: 077-3205634
    • North Holland
      • Amsterdam, North Holland, Netherlands, 1066 CX
        • Recruiting
        • Nederlands Kanker Instituut - Antoni van Leeuwenhoek - NKI-AVL ( Site 0602)
        • Contact:
          • Study Coordinator
          • Phone Number: 003120512 9111
      • Hilversum, North Holland, Netherlands, 1212 VG
        • Recruiting
        • Tergooiziekenhuizen, locatie Hilversum ( Site 0619)
        • Contact:
          • Study Coordinator
          • Phone Number: +31887535153
      • Hoofddorp, North Holland, Netherlands, 2134 TM
        • Recruiting
        • Spaarne Gasthuis - Hoofddorp ( Site 0608)
        • Contact:
          • Study Coordinator
          • Phone Number: +31232245802
    • Overijssel
      • Hengelo, Overijssel, Netherlands, 7555 DL
        • Recruiting
        • Ziekenhuisgroep Twente, locatie Almelo ( Site 0615)
        • Contact:
          • Study Coordinator
          • Phone Number: +31887083782
    • South Holland
      • Rotterdam, South Holland, Netherlands, 3015 GD
        • Recruiting
        • Erasmus Medisch Centrum ( Site 0611)
        • Contact:
          • Study Coordinator
          • Phone Number: 0031107041906
      • Schiedam, South Holland, Netherlands, 3118 JH
        • Recruiting
        • Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 0600)
        • Contact:
          • Study Coordinator
          • Phone Number: +31108931441
      • The Hague, South Holland, Netherlands, 2545 AA
        • Recruiting
        • Haga Ziekenhuis locatie Leyweg ( Site 0607)
        • Contact:
          • Study Coordinator
          • Phone Number: 070-210 2143
    • Utrecht
      • Amersfoort, Utrecht, Netherlands, 3813 TZ
        • Recruiting
        • Meander Medisch Centrum ( Site 0604)
        • Contact:
          • Study Coordinator
          • Phone Number: +3133850 7278
  • Norway
      • Oslo, Norway, 0379
        • Recruiting
        • Oslo universitetssykehus, Radiumhospitalet ( Site 0653)
        • Contact:
          • Study Coordinator
          • Phone Number: +4722934000
    • Akershus
      • Lorenskog, Akershus, Norway, 1474
        • Recruiting
        • Akershus Universitetssykehus-Onkologisk avdeling ( Site 0650)
        • Contact:
          • Study Coordinator
          • Phone Number: 004767960000
    • Oppland
      • Gjøvik, Oppland, Norway, 2819
        • Recruiting
        • Sykehuset Innlandet HF Gjøvik ( Site 0652)
        • Contact:
          • Study Coordinator
          • Phone Number: 004791506200
    • Sor-Trondelag
      • Trondheim, Sor-Trondelag, Norway, 7030
        • Recruiting
        • St. Olavs Hospital-Kreftklinikken ( Site 0651)
        • Contact:
          • Study Coordinator
          • Phone Number: +4772825810
  • Peru
      • Lima, Peru, 15036
        • Recruiting
        • IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0666)
        • Contact:
          • Study Coordinator
          • Phone Number: +5112241598
      • Lima, Peru, 15047
        • Recruiting
        • Instituto Neuro Cardiovascular de las Americas ( Site 0668)
        • Contact:
          • Study Coordinator
          • Phone Number: 51991366612
      • Lima, Peru, 15012
        • Recruiting
        • Hospital Cayetano Heredia ( Site 0667)
        • Contact:
          • Study Coordinator
          • Phone Number: 5112136000
      • Lima, Peru, 15038
        • Recruiting
        • Instituto Nacional de Enfermedades Neoplásicas ( Site 0665)
        • Contact:
          • Study Coordinator
          • Phone Number: +5112016500
    • Piura
      • Castilla, Piura, Peru, 20001
        • Recruiting
        • Unidad de Investigacion Oncologia Clínica Piura ( Site 0669)
        • Contact:
          • Study Coordinator
          • Phone Number: 51969618109
  • Poland
    • Greater Poland Voivodeship
      • Poznan, Greater Poland Voivodeship, Poland, 61-731
        • Recruiting
        • Clinical Research Center Spółka z ograniczoną odpowiedzialnością MEDIC-R Sp.k ( Site 0688)
        • Contact:
          • Study Coordinator
          • Phone Number: +48500 799 053
    • Kuyavian-Pomeranian Voivodeship
      • Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland, 85-796
        • Recruiting
        • Centrum Onkologii im prof Franciszka Lukaszczyka ( Site 0696)
        • Contact:
          • Study Coordinator
          • Phone Number: +48523743589
    • Lesser Poland Voivodeship
      • Krakow, Lesser Poland Voivodeship, Poland, 30-727
        • Recruiting
        • Pratia MCM Krakow ( Site 0692)
        • Contact:
          • Study Coordinator
          • Phone Number: +48122954100
    • Masovian Voivodeship
      • Siedlce, Masovian Voivodeship, Poland, 08-110
        • Recruiting
        • Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 0686)
        • Contact:
          • Study Coordinator
          • Phone Number: +48256403300
      • Warsaw, Masovian Voivodeship, Poland, 02-781
        • Recruiting
        • Narodowy Instytut Onkologii im. Marii Skłodowskiej Curie ( Site 0685)
        • Contact:
          • Study Coordinator
          • Phone Number: +48225462331
    • Silesian Voivodeship
      • Katowice, Silesian Voivodeship, Poland, 40-519
        • Recruiting
        • Pratia Onkologia Katowice ( Site 0693)
        • Contact:
          • Study Coordinator
          • Phone Number: +48327462500
  • Singapore
    • Central Singapore
      • Singapore, Central Singapore, Singapore, 168583
        • Recruiting
        • National Cancer Centre Singapore ( Site 0760)
        • Contact:
          • Study Coordinator
          • Phone Number: +6564368000
      • Singapore, Central Singapore, Singapore, 308433
        • Recruiting
        • Tan Tock Seng Hospital ( Site 0761)
        • Contact:
          • Study Coordinator
          • Phone Number: +6562566011
  • South Africa
    • Gauteng
      • Cape Town, Gauteng, South Africa, 7700
        • Recruiting
        • Cancercare Rondebosch Oncology ( Site 0771)
        • Contact:
          • Study Coordinator
          • Phone Number: +27219443700
      • Johannesburg, Gauteng, South Africa, 2193
        • Recruiting
        • Wits Clinical Research ( Site 0776)
        • Contact:
          • Study Coordinator
          • Phone Number: +27113390600
      • Pretoria, Gauteng, South Africa, 0081
        • Recruiting
        • Wilgers Oncology Centre ( Site 0775)
        • Contact:
          • Study Coordinator
          • Phone Number: +27 83 441 4889
      • Pretoria, Gauteng, South Africa, 0084
        • Recruiting
        • Curo Oncology Centre ( Site 0779)
        • Contact:
          • Study Coordinator
          • Phone Number: +27123356771
      • Pretoria, Gauteng, South Africa, 0181
        • Recruiting
        • LIFE GROENKLOOF ( Site 0777)
        • Contact:
          • Study Coordinator
          • Phone Number: +27123466701
  • South Korea
      • Seoul, South Korea, 03722
        • Recruiting
        • Severance Hospital Yonsei University Health System ( Site 0790)
        • Contact:
          • Study Coordinator
          • Phone Number: 82-2-2228-8138
      • Seoul, South Korea, 06351
        • Recruiting
        • Samsung Medical Center ( Site 0792)
        • Contact:
          • Study Coordinator
          • Phone Number: 82-2-3410-1767
    • Jeonranamdo
      • Hwasun Gun, Jeonranamdo, South Korea, 58128
        • Recruiting
        • Chonnam National University Hwasun Hospital ( Site 0794)
        • Contact:
          • Study Coordinator
          • Phone Number: 82-61-379-7623
    • Seoul
      • Seocho-gu, Seoul, South Korea, 06591
        • Recruiting
        • The Catholic University of Korea St. Mary s Hospital ( Site 0795)
        • Contact:
          • Study Coordinator
          • Phone Number: 82-2-2258-6806
      • Songpagu, Seoul, South Korea, 05505
        • Recruiting
        • Asan Medical Center ( Site 0791)
        • Contact:
          • Study Coordinator
          • Phone Number: 82-2-3010-6961
    • Ulsan-Kwangyokshi
      • Donggu, Ulsan-Kwangyokshi, South Korea, 44033
        • Recruiting
        • Ulsan University Hospital ( Site 0793)
        • Contact:
          • Study Coordinator
          • Phone Number: 82-52-230-1413
  • Spain
      • Barcelona, Spain, 08003
        • Recruiting
        • Hospital del Mar ( Site 0822)
        • Contact:
          • Study Coordinator
          • Phone Number: 34932483860
      • Barcelona, Spain, 08035
        • Recruiting
        • Hospital Vall D Hebron ( Site 0814)
        • Contact:
          • Study Coordinator
          • Phone Number: +34 93 4894374
      • Córdoba, Spain, 14004
        • Recruiting
        • Hospital Universitario Reina Sofia ( Site 0816)
        • Contact:
          • Study Coordinator
          • Phone Number: +34 957011464
      • Lugo, Spain, 27003
        • Recruiting
        • Hospital Lucus Augusti ( Site 0813)
        • Contact:
          • Study Coordinator
          • Phone Number: +343982296459
      • Madrid, Spain, 28223
        • Recruiting
        • Hospital Universitario Quiron Madrid ( Site 0823)
        • Contact:
          • Study Coordinator
          • Phone Number: +34914521987
      • Seville, Spain, 41014
        • Recruiting
        • Hospital Universitario Virgen de Valme ( Site 0819)
        • Contact:
          • Study Coordinator
          • Phone Number: +34955015273
      • Valencia, Spain, 46009
        • Recruiting
        • Fundación Instituto Valenciano de Oncología ( Site 0821)
        • Contact:
          • Study Coordinator
          • Phone Number: +34 96 111 42 29
    • Cantabria
      • Santander, Cantabria, Spain, 39008
        • Recruiting
        • Hospital Universitario Marqués de Valdecilla ( Site 0810)
        • Contact:
          • Study Coordinator
          • Phone Number: +34 +349422025155 25
    • La Coruna
      • Santiago de Compostela, La Coruna, Spain, 15706
        • Recruiting
        • CHUS - Hospital Clinico Universitario ( Site 0815)
        • Contact:
          • Study Coordinator
          • Phone Number: +34 663 609 134
    • Madrid
      • Majadahonda Madrid, Madrid, Spain, 28220
        • Recruiting
        • HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA ( Site 0811)
        • Contact:
          • Study Coordinator
          • Phone Number: +34911917418
    • Madrid, Comunidad de
      • Madrid, Madrid, Comunidad de, Spain, 28009
        • Recruiting
        • Hospital General Universitario Gregorio Marañón ( Site 0812)
        • Contact:
          • Study Coordinator
          • Phone Number: +34 914269393
  • Sweden
    • Skåne County
      • Malmö, Skåne County, Sweden, 20502
        • Recruiting
        • Skånes Universitetssjukhus Malmö ( Site 0841)
        • Contact:
          • Study Coordinator
          • Phone Number: 040331000
    • Stockholm County
      • Stockholm, Stockholm County, Sweden, 171 64
        • Recruiting
        • Karolinska Universitetssjukhuset Solna ( Site 0843)
        • Contact:
          • Study Coordinator
          • Phone Number: 46812370000
      • Stockholm, Stockholm County, Sweden, 11883
        • Recruiting
        • Södersjukhuset ( Site 0844)
        • Contact:
          • Study Coordinator
          • Phone Number: +46812361000
    • Östergötland County
      • Uppsala, Östergötland County, Sweden, 751 85
        • Recruiting
        • Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 0840)
        • Contact:
          • Study Coordinator
          • Phone Number: +46186110000
  • Switzerland
      • Fribourg, Switzerland, 1708
        • Recruiting
        • HFR Fribourg - Hôpital Cantonal ( Site 0858)
        • Contact:
          • Study Coordinator
          • Phone Number: +41263062260
      • Zurich, Switzerland, 8063
        • Recruiting
        • Stadtspital Triemli ( Site 0855)
        • Contact:
          • Study Coordinator
          • Phone Number: +41444163505
    • Canton of Aargau
      • Aarau, Canton of Aargau, Switzerland, 5001
        • Recruiting
        • Kantonspital Aarau ( Site 0857)
        • Contact:
          • Study Coordinator
          • Phone Number: +41628386050
    • Canton of Basel-City
      • Basel, Canton of Basel-City, Switzerland, 4031
        • Recruiting
        • University Hospital Basel ( Site 0859)
        • Contact:
          • Study Coordinator
          • Phone Number: +41612655074
    • Canton of Geneva
      • Geneva, Canton of Geneva, Switzerland, 1211
        • Recruiting
        • Hopitaux Universitaires de Geneve HUG. ( Site 0856)
        • Contact:
          • Study Coordinator
          • Phone Number: +41223722901
  • Taiwan
      • Kaohsiung City, Taiwan, 83301
        • Recruiting
        • Chang Gung Medical Foundation - Kaohsiung ( Site 0872)
        • Contact:
          • Study Coordinator
          • Phone Number: +88677317123x2270
      • Taichung, Taiwan, 40705
        • Recruiting
        • Taichung Veterans General Hospital ( Site 0873)
        • Contact:
          • Study Coordinator
          • Phone Number: +886423592525x5121
      • Taipei, Taiwan, 11217
        • Recruiting
        • Taipei Veterans General Hospital ( Site 0875)
        • Contact:
          • Study Coordinator
          • Phone Number: +88622871 2121
    • Taipei
      • Taiwan, Taipei, Taiwan, 10002
        • Recruiting
        • National Taiwan University Hospital ( Site 0870)
        • Contact:
          • Study Coordinator
          • Phone Number: +88623123456
  • Thailand
    • Bangkok
      • Bangkoknoi, Bangkok, Thailand, 10700
        • Recruiting
        • Faculty of Medicine Siriraj Hospital ( Site 0885)
        • Contact:
          • Study Coordinator
          • Phone Number: +6624194488
      • Dusit, Bangkok, Thailand, 10300
        • Recruiting
        • Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 0887)
        • Contact:
          • Study Coordinator
          • Phone Number: +6622443461
  • Turkey (Türkiye)
      • Adana, Turkey (Türkiye), 01140
        • Recruiting
        • Adana Medical Park Seyhan Hastanesi ( Site 0906)
        • Contact:
          • Study Coordinator
          • Phone Number: +905434352540
      • Ankara, Turkey (Türkiye), 06230
        • Recruiting
        • Hacettepe Universitesi Tip Fakultesi ( Site 0895)
        • Contact:
          • Study Coordinator
          • Phone Number: +90 5447363405
      • Ankara, Turkey (Türkiye), 06560
        • Recruiting
        • Gazi University Health Research and Application Center Gazi Hospital ( Site 0903)
        • Contact:
          • Study Coordinator
          • Phone Number: 5064450149
      • Ankara, Turkey (Türkiye), 06590
        • Recruiting
        • Ankara Universitesi Tıp Fakultesi Hastanesi ( Site 0901)
        • Contact:
          • Study Coordinator
          • Phone Number: +905076255017
      • Istanbul, Turkey (Türkiye), 34098
        • Recruiting
        • Istanbul Universitesi Cerrahpasa ( Site 0896)
        • Contact:
          • Study Coordinator
          • Phone Number: +9005348874207
      • Konya, Turkey (Türkiye), 42080
        • Recruiting
        • Konya Necmettin Erbakan Universitesi ( Site 0905)
        • Contact:
          • Study Coordinator
          • Phone Number: +905340537685
  • United Kingdom
    • United Kingdom
      • Devon, United Kingdom, United Kingdom, TQ2 7AA
        • Recruiting
        • Torbay Hospital ( Site 0918)
        • Contact:
          • Study Coordinator
          • Phone Number: +441803656615
  • United States
    • Arizona
      • Phoenix, Arizona, United States, 85054
        • Recruiting
        • Mayo Clinic in Arizona - Phoenix ( Site 0044)
        • Contact:
          • Study Coordinator
          • Phone Number: 855-776-0015
    • California
      • Duarte, California, United States, 91010
        • Recruiting
        • City of Hope Comprehensive Cancer Center ( Site 0049)
        • Contact:
          • Study Coordinator
          • Phone Number: 626-256-4673
      • Irvine, California, United States, 92618
        • Recruiting
        • City of Hope Lennar Foundation Cancer Center ( Site 0059)
        • Contact:
          • Study Coordinator
          • Phone Number: 626-256-4673
      • La Jolla, California, United States, 92093
        • Recruiting
        • Moores Cancer Center ( Site 0010)
        • Contact:
          • Study Coordinator
          • Phone Number: 858-822-6100
      • Los Angeles, California, United States, 90048
        • Recruiting
        • Cedars-Sinai Medical Center ( Site 0068)
        • Contact:
          • Study Coordinator
          • Phone Number: 310-423-7600
      • Los Angeles, California, United States, 90404
        • Recruiting
        • UCLA Hematology/Oncology - Santa Monica ( Site 0002)
        • Contact:
          • Study Coordinator
          • Phone Number: 310-825-2631
      • Orange, California, United States, 92868
        • Recruiting
        • University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0006)
        • Contact:
          • Study Coordinator
          • Phone Number: 714-509-2371
      • Palo Alto, California, United States, 94304
        • Recruiting
        • Stanford Cancer Center ( Site 0046)
        • Contact:
          • Study Coordinator
          • Phone Number: 650-725-2078
    • Colorado
      • Aurora, Colorado, United States, 80045
        • Recruiting
        • Rocky Mountain Regional Veterans Affairs Medical Center ( Site 0053)
        • Contact:
          • Study Coordinator
          • Phone Number: 303-399-8020
    • Connecticut
      • New Haven, Connecticut, United States, 06510
        • Recruiting
        • Yale-New Haven Hospital-Yale Cancer Center ( Site 0050)
        • Contact:
          • Study Coordinator
          • Phone Number: 203-737-6087
      • West Haven, Connecticut, United States, 06516
        • Recruiting
        • Veterans Affairs Connecticut Healthcare System ( Site 0062)
        • Contact:
          • Study Coordinator
          • Phone Number: 203-932-5711
    • District of Columbia
      • Washington D.C., District of Columbia, United States, 20422
        • Recruiting
        • Washington DC Veterans Affairs Medical Center ( Site 0056)
        • Contact:
          • Study Coordinator
          • Phone Number: 202-745-8000
      • Washington D.C., District of Columbia, United States, 20037
        • Recruiting
        • The GW Medical Faculty Associates ( Site 0057)
        • Contact:
          • Study Coordinator
          • Phone Number: 202-994-2758
    • Florida
      • Jacksonville, Florida, United States, 32224
        • Recruiting
        • Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0077)
        • Contact:
          • Study Coordinator
          • Phone Number: 855-776-0015
    • Georgia
      • Atlanta, Georgia, United States, 30303
        • Recruiting
        • Emory University School of Medicine- Grady Campus ( Site 0103)
        • Contact:
          • Study Coordinator
          • Phone Number: 404-727-6123
      • Atlanta, Georgia, United States, 30322
        • Recruiting
        • Winship Cancer Institute, Emory University ( Site 0003)
        • Contact:
          • Study Coordinator
          • Phone Number: 404-778-4824
    • Illinois
      • Chicago, Illinois, United States, 60612
        • Recruiting
        • University of Illinois at Chicago-University of Illinois Cancer Center ( Site 0063)
        • Contact:
          • Study Coordinator
          • Phone Number: 312-355-1625
      • Chicago, Illinois, United States, 60607
        • Recruiting
        • Rush University Medical Center-Hematology and Oncology ( Site 0028)
        • Contact:
          • Study Coordinator
          • Phone Number: 312-563-2531
    • Kentucky
      • Lexington, Kentucky, United States, 40536
        • Recruiting
        • University of Kentucky Chandler Medical Center ( Site 0048)
        • Contact:
          • Study Coordinator
          • Phone Number: 866-340-4488
    • Maryland
      • Baltimore, Maryland, United States, 21201
        • Recruiting
        • Greenebaum Comprehensive Cancer Center ( Site 0021)
        • Contact:
          • Study Coordinator
          • Phone Number: 410-707-4011
    • Massachusetts
      • Boston, Massachusetts, United States, 02215
        • Recruiting
        • Beth Israel Deaconess Medical Center ( Site 0043)
        • Contact:
          • Study Coordinator
          • Phone Number: 617-667-2100
      • Boston, Massachusetts, United States, 02215
        • Recruiting
        • Dana Farber Cancer Institute ( Site 0012)
        • Contact:
          • Study Coordinator
          • Phone Number: 617-632-6049
    • Michigan
      • Ann Arbor, Michigan, United States, 48109
        • Recruiting
        • University of Michigan ( Site 0005)
        • Contact:
          • Study Coordinator
          • Phone Number: 734-647-8902
      • Detroit, Michigan, United States, 48202
        • Recruiting
        • Henry Ford Hospital ( Site 0035)
        • Contact:
          • Study Coordinator
          • Phone Number: 313-725-7920
      • Grand Rapids, Michigan, United States, 49503
        • Recruiting
        • Cancer and Hematology Centers of Western Michigan ( Site 0015)
        • Contact:
          • Study Coordinator
          • Phone Number: 616-399-6500
    • Minnesota
      • Rochester, Minnesota, United States, 55905
        • Recruiting
        • Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0078)
        • Contact:
          • Study Coordinator
          • Phone Number: 855-776-0015
      • Saint Louis Park, Minnesota, United States, 55426
        • Recruiting
        • HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0032)
        • Contact:
          • Study Coordinator
          • Phone Number: 612-341-4800
      • Saint Paul, Minnesota, United States, 55101
        • Recruiting
        • HealthPartners Cancer Center at Regions Hospital ( Site 0052)
        • Contact:
          • Study Coordinator
          • Phone Number: 612-341-4800
    • Montana
      • Billings, Montana, United States, 59102
        • Recruiting
        • St. Vincent Frontier Cancer Center-Research ( Site 0037)
        • Contact:
          • Study Coordinator
          • Phone Number: 406-238-6290
    • Nebraska
      • Grand Island, Nebraska, United States, 68803
        • Completed
        • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Grand Island ( Site 0076)
      • Omaha, Nebraska, United States, 68130
        • Completed
        • Oncology Hematology West P.C. dba Nebraska Cancer Specialists ( Site 0026)
    • Nevada
      • Las Vegas, Nevada, United States, 89148
        • Recruiting
        • Comprehensive Cancer Centers of Nevada ( Site 0082)
        • Contact:
          • Study Coordinator
          • Phone Number: 702-952-1251
    • New Jersey
      • Hackensack, New Jersey, United States, 07601
        • Recruiting
        • John Theurer Cancer Center at Hackensack University Medical Center ( Site 0016)
        • Contact:
          • Study Coordinator
          • Phone Number: 551-996-5900
    • New Mexico
      • Albuquerque, New Mexico, United States, 87131
        • Recruiting
        • University of New Mexico Comprehensive Cancer Center ( Site 0022)
        • Contact:
          • Study Coordinator
          • Phone Number: 505-272-4946
    • New York
      • New York, New York, United States, 10029
        • Recruiting
        • Icahn School of Medicine at Mount Sinai ( Site 0009)
        • Contact:
          • Study Coordinator
          • Phone Number: 212-241-6756
      • Williamsville, New York, United States, 14221
        • Recruiting
        • Great Lakes Cancer Care ( Site 0047)
        • Contact:
          • Study Coordinator
          • Phone Number: 716-884-3000
    • Ohio
      • Columbus, Ohio, United States, 43221
        • Recruiting
        • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0061)
        • Contact:
          • Study Coordinator
          • Phone Number: 619-228-4010
    • Oregon
      • Portland, Oregon, United States, 97239
        • Recruiting
        • VA Portland Health Care System ( Site 0038)
        • Contact:
          • Study Coordinator
          • Phone Number: 503-220-8262
    • Pennsylvania
      • Philadelphia, Pennsylvania, United States, 19104
        • Recruiting
        • Perelman Center for Advanced Medicine ( Site 0067)
        • Contact:
          • Study Coordinator
          • Phone Number: 215-360-0737
      • Philadelphia, Pennsylvania, United States, 19106
        • Recruiting
        • Abramson Cancer Center - Penn Medicine ( Site 0079)
        • Contact:
          • Study Coordinator
          • Phone Number: 215-829-6088
    • Tennessee
      • Memphis, Tennessee, United States, 38105
        • Recruiting
        • Memphis VA Medical Center ( Site 0072)
        • Contact:
          • Study Coordinator
          • Phone Number: 901-523-8990
      • Nashville, Tennessee, United States, 37203
        • Recruiting
        • SCRI Oncology Partners ( Site 0074)
        • Contact:
          • Study Coordinator
          • Phone Number: 615-329-7640
      • Nashville, Tennessee, United States, 37232
        • Recruiting
        • Henry-Joyce Cancer Clinic ( Site 0042)
        • Contact:
          • Study Coordinator
          • Phone Number: 615-936-8422
    • Texas
      • Dallas, Texas, United States, 75390
        • Recruiting
        • UT Southwestern Medical Center ( Site 0039)
        • Contact:
          • Study Coordinator
          • Phone Number: 972-332-4682
      • Houston, Texas, United States, 77030
        • Recruiting
        • University of Texas-MD Anderson Cancer Center ( Site 0055)
        • Contact:
          • Study Coordinator
          • Phone Number: 877-632-6789
    • Virginia
      • Roanoke, Virginia, United States, 24014
        • Recruiting
        • Blue Ridge Cancer Care ( Site 0024)
        • Contact:
          • Study Coordinator
          • Phone Number: 540-982-0237
    • Washington
      • Seattle, Washington, United States, 98108
        • Recruiting
        • VA Puget Sound Health Care System ( Site 0054)
        • Contact:
          • Study Coordinator
          • Phone Number: 206-762-1010
      • Seattle, Washington, United States, 98109
        • Recruiting
        • Fred Hutchinson Cancer Center ( Site 0060)
        • Contact:
          • Study Coordinator
          • Phone Number: 206-606-7307
    • Wisconsin
      • Madison, Wisconsin, United States, 53792
        • Recruiting
        • University Hospital and UW Health Clinics ( Site 0065)
        • Contact:
          • Study Coordinator
          • Phone Number: 608-915-0100
      • Milwaukee, Wisconsin, United States, 53226
        • Recruiting
        • Medical College of Wisconsin ( Site 0008)
        • Contact:
          • Study Coordinator
          • Phone Number: 414-805-0509

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

The main inclusion criteria include but are not limited to the following:

  • Has histologically- or cytologically-confirmed adenocarcinoma of the prostate without small cell histology
  • Has prostate cancer progression while on androgen deprivation therapy (ADT) (or post bilateral orchiectomy) within 6 months prior to Screening
  • Has current evidence of distant metastatic disease (M1 disease) documented by either bone lesions on bone scan and/or soft tissue disease by computed tomography (CT)/magnetic resonance imaging (MRI)
  • Has received prior treatment with 1 or 2 androgen receptor pathway inhibitors (ARPIs) and progressed during or after at least 8 weeks of treatment
  • Has provided tumor tissue from a core or excisional biopsy from soft tissue not previously irradiated and obtained after disease progression on the most recent prior therapy
  • Has recovered from adverse events (AEs) due to previous anticancer therapies

Exclusion Criteria:

The main exclusion criteria include but are not limited to the following:

  • Is unable to swallow tablets/capsules

  • Has any of the following indicators of interstitial lung disease (ILD)/pneumonitis:

    1. Has any history of ILD/pneumonitis that required steroid use, except for a history of radiation pneumonitis that did not require steroids
    2. Has current ILD/pneumonitis
    3. Has a clinical or radiographic suspicion of ILD for which the diagnosis of ILD cannot be ruled out
  • Has clinically severe pulmonary compromise resulting from intercurrent pulmonary illnesses
  • Has uncontrolled or significant cardiovascular disease
  • Has received prior treatment with a taxane-based chemotherapy agent for metastatic castration-resistant prostate cancer (mCRPC)
  • Has had prior discontinuation of an antibody drug conjugate (ADC) that consists of an exatecan derivative (eg, trastuzumab deruxtecan) due to treatment-related toxicities
  • Has a "superscan" bone scan

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: I-DXd
Participants receive I-DXd 12mg/kg every 3 weeks (q3w)
Drug: Ifinatamab deruxtecan
Administered via intravenous (IV) infusion every 3 weeks (q3w) until disease progression, unacceptable adverse events (AEs), or other cessation of treatment
Other Names:
  • DS-7300a
  • I-DXd
  • MK-2400
Drug: Rescue Medication
Before administering each dose of I-DXd, premedication is required for prevention of nausea and vomiting with a 2 or 3 drug combination regimen (eg, corticosteroids with either a 5-HT3 receptor antagonist or an NK-1 receptor antagonist and other drugs as indicated) per approved product label
Other Names:
  • Corticosteroid
  • 5-HT3 receptor antagonist
  • NK-1 receptor antagonist
Active Comparator: Docetaxel
Participants receive docetaxel 75 mg/m^2 q3w and prednisone 10 mg/day or per approved product label
Drug: Docetaxel
Administered via IV infusion q3W until disease progression, unacceptable adverse events (AEs), or other cessation of treatment
Drug: Prednisone
Oral tablet administered once per day or per approved product label
Other Names:
  • Prednisolone
  • Prednisolone acetate
  • Prednisone acetate

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Overall Survival (OS)
Time Frame: Up to approximately 36 months
OS is defined as the time from randomization to death due to any cause.
Up to approximately 36 months
Radiographic Progression Free Survival (rPFS)
Time Frame: Up to approximately 36 months
rPFS is defined as the time from randomization to the first documented disease progression per prostate cancer working group (PCWG)-modifed Response Evaluation Criteria In Solid Tumors (RECIST) 1.1 by blinded independent central review (BICR) or death due to any cause, whichever occurs first.
Up to approximately 36 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Time to First Subsequent Therapy (TFST)
Time Frame: Up to approximately 36 months
TFST is defined as the time from randomization to initiation of the first subsequent anticancer therapy or death, whichever occurs first.
Up to approximately 36 months
Duration of Response (DOR)
Time Frame: Up to approximately 36 months
For participants who demonstrate confirmed CR or PR, DOR is defined as the time from the first documented evidence of CR or PR until disease progression per PCWG-modified RECIST 1.1 as assessed by BICR or death due to any cause, whichever occurs first.
Up to approximately 36 months
Time to Pain Progression (TTPP)
Time Frame: Up to approximately 36 months
TTPP is defined as the time from randomization to pain progression based on the brief pain inventory-short form (BPI-SF) Item 3 "worst pain in 24 hours" and opiate analgesic use (AQA score).
Up to approximately 36 months
Time to Prostate-specific Antigen (PSA) Progression
Time Frame: Up to approximately 36 months
Time to PSA progression is defined as the time from randomization to PSA progression. The PSA progression date is defined as the first date that 1) ≥25% increase and ≥2 ng/mL above the nadir which is confirmed by a second value≥3 weeks later if there is PSA decline from baseline, 2) ≥25% increase and ≥2 ng/mL increase from baseline beyond 12 weeks if there is no PSA decline from baseline.
Up to approximately 36 months
Number of Participants Who Discontinue Study Treatment Due to an Adverse Event (AE)
Time Frame: Up to approximately 36 months

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.

An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention.
Up to approximately 36 months
Objective Response Rate (ORR)
Time Frame: Up to approximately 36 months
The ORR is defined as a confirmed complete response (CR) or partial response (PR) per PCWG-modified RECIST 1.1 as assessed by BICR.
Up to approximately 36 months
PSA Response Rate
Time Frame: Up to approximately 36 months
PSA response rate is defined as the proportion of participants in the analysis population who have a PSA reduction of ≥50% from baseline with a consecutive confirmation assessment at least 3 weeks later per PCWG criteria.
Up to approximately 36 months
Time to First Symptomatic Skeletal-Related Event (SSRE)
Time Frame: Up to approximately 36 months

Time to first SSRE is defined as the time from randomization to the first occurrence of any of the following symptomatic skeletal-related events:

  1. use of EBRT to prevent or relieve skeletal symptoms,
  2. new symptomatic pathologic bone fracture (vertebral or non-vertebral),
  3. spinal cord compression,
  4. a tumor-related orthopedic surgical intervention.
Up to approximately 36 months
Number of Participants Who Experienced at Least One Adverse Event (AE)
Time Frame: Up to approximately 36 months

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.

An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of a study intervention.
Up to approximately 36 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Merck Sharp & Dohme LLC

Collaborators

Daiichi Sankyo

Investigators

  • Study Director: Medical Director, Merck Sharp & Dohme LLC

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 13, 2025

Primary Completion (Estimated)

June 26, 2028

Study Completion (Estimated)

January 6, 2031

Study Registration Dates

First Submitted

April 7, 2025

First Submitted That Met QC Criteria

April 7, 2025

First Posted (Actual)

April 13, 2025

Study Record Updates

Last Update Posted (Actual)

May 29, 2026

Last Update Submitted That Met QC Criteria

May 27, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2400-001
  • U1111-1312-2498 (Registry Identifier: UTN)
  • 2024-517423-40-00 (Registry Identifier: EU CT)
  • MK-2400-001 (Other Identifier: MSD)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

https://trialstransparency.msdclinicaltrials.com/pdf/ProcedureAccessClinicalTrialData.pdf

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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