MultiCPR: The Influence of Ventilations on Mental Arithmetics (MultiCPR2)

December 28, 2025 updated by: Mathias Maleczek, Medical University of Vienna

The purpose of this clinical study is to investigate how performing ventilations during pediatric resuscitation affects the ability to perform mental tasks. In particular, the effect on the participant's ability to perform dose calculations will be investigated. The aim is to draw conclusions about the effects of ventilations on other mental tasks.

How does the clinical trial work? This clinical trial will be conducted in several locations and will involve a total of 38 people. The study will be conducted by the Department of Anesthesiology of the Medical University of Vienna.

Participation in this clinical study is expected to last 30 minutes.

The following measures will be carried out exclusively for study reasons:

Depending on the sub-study you are participating in, different tasks will be performed:

Adult sub-study:

During this study, participants will be asked to perform mental arithmetic: Participants will be read a number every 2 seconds and have to add the last two in each case. The numbers are predetermined and randomly generated. At the end, we will evaluate how many results were correct.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

38

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Austria
      • Vienna, Austria, 1210
        • Academic Simulation Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion:

  • Healthy medical professionals trained in CPR (paramedics, prehospital emergency physicians, anesthesiologists, internal medicine doctors, nurses, midwifery students, pediatricians)
  • CPR Training in the last four years
  • Fit and rested.

Exclusion:

- Pregnant probands

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Ventilations/CPR
Calculations made with/without performing ventilations - cross over design to decide what to do first, NASA-TLX will be measured
Behavioral: Dose Calculations
Dose calculations either with or without performing ventilations during CPR (15:2)
Procedure: Ventilations
Performing ventilations during CPR in a 15:2 manner
Active Comparator: no ventilations/CPR
Calculations made with/without performing ventilations - cross over design to decide what to do first, NASA-TLX will be measured
Behavioral: Dose Calculations
Dose calculations either with or without performing ventilations during CPR (15:2)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Dose calculations
Time Frame: during 2x2 minutes of inclusion
Number of correct calculations
during 2x2 minutes of inclusion

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
NASA-TLX
Time Frame: 4 minutes, 2 times in total per participant
Nasa Task load index (min: 0, max: 120, higher scores mean higher cognitive load)
4 minutes, 2 times in total per participant

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Medical University of Vienna

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 7, 2025

Primary Completion (Actual)

November 26, 2025

Study Completion (Actual)

November 26, 2025

Study Registration Dates

First Submitted

April 29, 2025

First Submitted That Met QC Criteria

May 20, 2025

First Posted (Actual)

May 22, 2025

Study Record Updates

Last Update Posted (Estimated)

January 2, 2026

Last Update Submitted That Met QC Criteria

December 28, 2025

Last Verified

December 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MultiCPR_2

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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