Search clinical trials for: Sirolimus

Total 1117 results

Masaryk University

Unknown

Comparison of Biolimus A9 and Everolimus Drug-Eluting Stents in Patients With ST Segment Elevation Myocardial Infarction (ROBUST)

Coronary Heart Disease | Percutaneous Coronary Intervention

Czech Republic
Biosensors Europe SA

Unknown

BioFreedom QCA Study in CAD Patients (BioFreedomQCA)

Myocardial Infarction | Coronary Artery Disease | Cardiac Death

Spain, Denmark
Translational Research Center for Medical Innovation...
Wakayama Medical University

Completed

OPtical Frequency Domain Imaging vs. INtravascular Ultrasound in Percutaneous Coronary InterventiON (OPINION)

Coronary Artery Disease

Japan
Terumo Europe N.V.

Completed

Randomized Study to Assess the Effect of ThRombus Aspiration on Flow Area in STEMI Patients (TROFI)

Myocardial Infarction | Coronary Artery Disease | STEMI

Germany, France, Denmark, Netherlands
Odense University Hospital

Unknown

Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent (SORT OUT VII)

Coronary Artery Disease | Ischemic Heart Disease

Denmark
Translational Research Center for Medical Innovation...
Wakayama Medical University

Completed

OPtical Frequency Domain Imaging Versus INtravascular Ultrasound in Percutaneous Coronary InterventiON - OPINION Imaging

Coronary Artery Disease

Japan
Aadi Bioscience, Inc.

Approved for marketing

Expanded Access for ABI-009 in Patients With Advanced PEComa and Patients With a Malignancy With Relevant Genetic Mutations or mTOR Pathway Activation

TSC1 | TSC2 | PEComa, Malignant | mTOR Pathway Abberation
Yonsei University

Unknown

Impact of Intravascular Ultrasound(IVUS)-Guided Chronic Total Occlusion Intervention With Drug-eluting Stents (CTO)

Coronary Artery Disease

Korea, Republic of
Johns Hopkins University
MacuSight, Inc.

Completed

Sirolimus as Therapeutic Approach to Uveitis (SAVE)

Panuveitis | Uveitis | Posterior Uveitis | Intermediate Uveitis

United States
Aadi Bioscience, Inc.

Completed

Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma

High Grade Recurrent Glioma and Newly Diagnosed Glioblastoma

United States
Stefan Schieke MD

Withdrawn

Therapeutic Efficacy of Topical Sirolimus in Early Stage Cutaneous T-cell Lymphoma (CTCL)

Cutaneous T-cell Lymphoma (CTCL)

United States
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety Study of Sirolimus and Hydroxychloroquine in Women With Lymphangioleiomyomatosis (SAIL)

Lymphangioleiomyomatosis

United States
Phillip Freeman
Odense University Hospital; Aarhus University Hospital; Biosensors International and other collaborators

Active, not recruiting

Sort Out XI - Combo Stent Versus BioMatrix Alpha Stent (SORTOUTXI)

Coronary Artery Disease

Denmark
AgelessRx
University of California, Los Angeles

Completed

Participatory Evaluation (of) Aging (With) Rapamycin (for) Longevity Study (PEARL)

Aging

United States
The University of Texas Health Science Center,...
Society for Pediatric Dermatology

Completed

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

Tuberous Sclerosis | Neurofibromatoses | Neurofibroma | Angiofibroma

United States
Xijing Hospital
Air Force Military Medical University, China; Shanghai MicroPort Medical (Group)... and other collaborators

Unknown

Long Term Efficacy and Safety of Firebird Sirolimus-Eluting Stent In Complex Coronary Lesions (FIREMAN)

Coronary Disease

China
Shanghai Jiao Tong University School of Medicine

Unknown

Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease (FESTA)

Coronary Artery Disease

China
Paul S Teirstein, MD
Cordis Corporation

Completed

The SCRIPPS DES REAL WORLD Registry

Coronary Artery Disease | Coronary Thrombosis | Coronary Restenosis

United States
Meril Life Sciences Pvt. Ltd.
Lifecare Institute of Medical Sciences and Research Ahmedabad Gujarat India

Completed

Study Safety and Performance of the Biomime Stent in Patients With Single, De Novo, Non-Complex Coronary Lesions (meriT-1)

Coronary Artery Disease

India
Aucta Pharmaceuticals, Inc

Terminated

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Tuberous Sclerosis | Angiofibroma of Face

United States, China
OrbusNeich
CCRF Inc., Beijing, China; OrbusNeich Medical (Shenzhen), Co. Ltd.

Completed

Safety and Efficacy of the Combo Bio-engineered Sirolimus-eluting Stent Versus the Nano Polymer-free Sirolimus-eluting Stent in the Treatment of Patients With de Novo Stenotic Lesions (RECOVERY)

Coronary Arteriosclerosis

China
Cordis Corporation

Completed

FIM-BR - First-in-Man Study (Brazil Part) With Sirolimus-Coated BX VELOCITY Stent

Coronary Artery Disease

Brazil
Children's Hospital of Fudan University

Completed

Safety and Efficacy of Low-dose Sirolimus to Kaposiform Hemangioendothelioma

Hemangioma | Kaposiform Hemangioendothelioma

China
Nanjing First Hospital, Nanjing Medical University

Withdrawn

Coronary Bifurcation Lesions Treated With Biguard Stent System (BIGUARD)

Coronary Artery Disease
Concept Medical Inc.

Completed

Clinical Use and Safety of the Xtreme Touch (Magic Touch PTA)- Neo Sirolimus Coated PTA Balloon Catheter in the Treatment of Infrainguinal Peripheral Arterial Disease (XTOSI)

Atherosclerosis | Peripheral Artery Disease

Singapore
Deutsches Herzzentrum Muenchen

Unknown

Test of Long-Term Safety and Efficacy of Sirolimus-Permanent-Polymer Eluting Stent (Cypher)- and Sirolimus-Polymer-free Eluting Stents (PPS/PFS) Assessed by Optical Coherence Tomography (PPS/PFS-OCT)

Coronary Heart Disease

Germany
Robbert J de Winter

Unknown

Prospective Registry to Asses the Long-term Safety and Performance of the Combo Stent (REMEDEE Reg)

Coronary Artery Disease

Netherlands, Latvia, United Kingdom, Luxembourg, Spain
Samsung Medical Center

Completed

Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors

Refractory Solid Tumors

Korea, Republic of
University of Manitoba
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney Transplant

Kidney Transplantation

Canada
University of Washington
Aadi Bioscience, Inc.

Active, not recruiting

Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas

Advanced Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma

United States
Tufts University
National Research Council, Spain

Completed

Immunological Impact of High Olive Oil Consumption (OOS)

Immune Factors

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Sirolimus for Eosinophil-Associated Gastrointestinal Disorders

Eosinophilic Gastroenteritis | Eosinophilic Esophagitis

United States
Samsung Medical Center

Completed

The Pilot Study Evaluate the Safety and Efficacy of Sirolimus in Patients With PIK3CA Mutation and/or PIK3CA Amplification Refractory Solid Tumors

Solid Tumor

Korea, Republic of
Beijing Anzhen Hospital

Unknown

The Study of Active Transfer of Plaque Technique for Non-Left Main Coronary Bifurcation Lesions

Coronary Heart Disease
Nobelpharma

Completed

Bioequivalence Study of NPC-12 (Sirolimus) Granules and Tablets

Bioequivalence Study

Japan
National Institute of Allergy and Infectious Diseases...
Autoimmunity Centers of Excellence

Terminated

Treating Multiple Sclerosis With Sirolimus, an Immune System Suppressor

Multiple Sclerosis (MS) - Relapsing-remitting

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating Rapamune in Patients After Kidney Transplantation

Renal Transplantation

Germany
Universitaire Ziekenhuizen KU Leuven

Completed

STACCATO: Stent sTrut Apposition and Coverage in Coronary ArTeries: an Optical Coherence Tomography (OCT) Study (STACCATO)

Coronary Artery Disease

Belgium
Meril Life Sciences Pvt. Ltd.

Unknown

BioMime Vs. Xience Randomised Control Clinical Study (meriT-V)

Coronary Artery Disease

United Kingdom, Brazil, Spain, Macedonia, The Former Yugoslav Republic of, Belgium, Czechia, Latvia, Netherlands, Poland
University of Virginia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Diffuse Parenchymal Lung Disease

United States
Pfizer

Completed

Study Investigating Rapamune For Post-Marketing Surveillance

Kidney Transplantation

Korea, Republic of
Fudan University

Unknown

Sirolimus-Based Immunosuppression Therapy in OLT for Patients With HCC Exceeding Milan Criteria

Hepatocellular Carcinoma

China
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Discovery of Sirolimus Sensitive Biomarkers in Blood

Lymphangioleiomyomatosis

United States
Dermatology Specialties Limited Partnership

Completed

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Tuberous Sclerosis | Facial Angiofibroma

United States, Taiwan, Serbia, Spain, Australia, Czechia, Hungary, New Zealand, Slovakia
Singapore General Hospital

Active, not recruiting

Prospective Registry to Investigate the Safety and Efficacy of the Treatment With the Selution Sirolimus Drug Coated Balloon in TASC C and D Atheroma-occlusive Infra-Inguinal Disease in Patients With Chronic Limb Threatening Ischemia From Singapore (PRISTINE)

Peripheral Artery Disease | Critical Lower Limb Ischemia

Singapore
Drexel University

Completed

Novel Compositions for Treating or Preventing Dermal Disorders

Dermal Atrophy

United States
Children's Hospital of Philadelphia
The Leukemia and Lymphoma Society; National Childhood Cancer Foundation

Terminated

Sirolimus in Treating Young Patients With Relapsed or Refractory Acute Leukemia or Non-Hodgkin's Lymphoma

Lymphoma | Leukemia

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Completed

Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma

Sarcoma

United States
Instituto de Oftalmología Fundación Conde de Valenciana

Completed

Liposomal Sirolimus in Dry Eye Disease

Dry Eye

Mexico
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Sirolimus (Rapamune™) in Solid Organ Transplant Recipients

Kidney Transplantation | Graft vs Host Disease

Canada, United States

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