The Epidemiology Change From 2006 to 2022 of Infective Endocarditis in Taiwan

September 1, 2025 updated by: National Taiwan University Clinical Trial Center, National Taiwan University Hospital
Infective endocarditis has long been one of the significant diseases causing death and disability worldwide. Its incidence has shown an increasing trend over the past few decades. Moreover, there seems to be significant variation in prevalence and epidemiology in different geographic regions and countries. This study aims to understand the trends and changes in the epidemiology of infective endocarditis in Taiwan from the 2006s to the present. Through a retrospective database analysis using the "Taiwan Healthcare System Integration Database," the goal is to improve the prognosis of infective endocarditis treatment in Taiwan.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

2247

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022

Description

Inclusion Criteria:

  • Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022

Exclusion Criteria:

  • Patients without infective endocarditis

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Recent epidemiological trends and changes in infective endocarditis in Taiwan over the past decades
Time Frame: 2006 to 2022
2006 to 2022

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 8, 2023

Primary Completion (Estimated)

December 31, 2025

Study Completion (Estimated)

December 31, 2025

Study Registration Dates

First Submitted

April 28, 2025

First Submitted That Met QC Criteria

September 1, 2025

First Posted (Estimated)

September 5, 2025

Study Record Updates

Last Update Posted (Estimated)

September 5, 2025

Last Update Submitted That Met QC Criteria

September 1, 2025

Last Verified

April 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 202309097RINB

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

local epidemiology in order

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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