The Bone Thickness of Infrazygomatic Crest Was Measured on CBCTs (IZC)

November 25, 2025 updated by: Fady Hussein, Cairo University

Assessment of Bone Thickness in the Infrazygomatic Crest and Proper Insertion Angle for Miniscrew Positioning: A Retrospective CBCT Study

This study will be done on 95 patients with CBCTs retrospectively, to evaluate the bone depth of infrazygomatic crest region for selecting suitable size of miniscrews and proper insertion angle clinical guide in the infrazygomatic crest without injuring the mesiobuccal root of the maxillary first molar.

Study Overview

Status

Completed

Conditions

Detailed Description

CBCTs of 95 patients were collected retrospectively from archives of Faculty of Dentistry, Cairo University, that were requested for different dental purposes. The thickness of the IZC was measured above mesio-buccal root of upper 6 (U6MB), above disto-buccal root of upper 6 (U6DB) and contact point between upper 6 and 7 roots (U6-7). The distance from point of entry of miniscrew to the occlusal plane, that saves roots from injury, was measured. Then, the angle of miniscrew insertion in relation to the occlusal plane was measured at maximum thickness available together with point of entry in relation to the occlusal plane. The IZC thickness of right and left sides of each patient was compared, also compared in males and females. Kruskal-Wallis test, Paired Wilcoxon signed rank test & Spearman correlation were used to analyze results

Study Type

Observational

Enrollment (Actual)

95

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Cairo, Egypt
        • Faculty of Dentistry Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

This study will be done on 100 CBCTs of 95 patients; 58 females and 37 males retrospectively to evaluate the bone depth of infrazygomatic crest region for selecting suitable size of miniscrews and proper insertion angle clinical guide in the infrazygomatic crest without injuring the mesiobuccal root of the maxillary first molar.

Description

Inclusion Criteria:

  • Patients having full permanent dentition
  • all cases were indicated for CBCT for their orthodontic treatment
  • Patients with sound dentition

Exclusion Criteria:

  • craniofacial anomalies and facial asymmetries
  • Unclear CBCT
  • mixed dentition
  • Patients with systemic bone disorders

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
95 patients were randomly chosen constituting both males and females
Following the inclusion and exclusion criteria, 95 patients were randomly chosen constituting both males and females with an age range of 20-35 years old (58 females and 37 males). CBCTs were acquired in the same manner, using an i-CAT scanner with 110 kVp, 60 mA, 0.3-mm voxel size, a scan time of 18 seconds, and a field of view of 17x 23 cm. CBCT measurements were analyzed using Invivo 6 (Anatomage, Inc., Santa Clara, Calif). These tomographic images were reoriented so that the natural head position coincided with the true horizontal plane in an attempt to reduce possible errors in head positioning during image acquisition.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
measure bone thickness of infrazygomatic crest
Time Frame: from enrollment to the end of taking measurements at 8 weeks
the bone thickness will be measured on CBCT from coronal slice at 3 points : above mesio-buccal root of upper first molar, above disto-buccal root of upper first molar and between upper first and second molars contact points
from enrollment to the end of taking measurements at 8 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
proper angulation of miniscrew insertion
Time Frame: from enrollment to the end of taking measurements at 8 weeks
a clinical guide to clinicians was done to guide the clinician the proper angulation of long axis of miniscrew and occlusal plane
from enrollment to the end of taking measurements at 8 weeks
check asymmetry of right and left sides per patient
Time Frame: from enrollment to the end of taking measurements at 8 weeks
the right and left bone thickness was measured to detect any asymmetry between both sides
from enrollment to the end of taking measurements at 8 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 24, 2025

Primary Completion (Actual)

September 30, 2025

Study Completion (Actual)

September 30, 2025

Study Registration Dates

First Submitted

August 23, 2025

First Submitted That Met QC Criteria

November 25, 2025

First Posted (Actual)

December 8, 2025

Study Record Updates

Last Update Posted (Actual)

December 8, 2025

Last Update Submitted That Met QC Criteria

November 25, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 31-3-22

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

mean age of the patients mean thickness of infrazygomatic crest

IPD Sharing Time Frame

start date for IPD sharing : 1 December, 2025 start date for IPD sharing : 1 December, 2026

IPD Sharing Access Criteria

anyone will be able to access the IPD and supporting information, they will be able to access study protocol, they will be able to access it by sending Email to fady.fahim@gmail.com

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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