A Clinical Trial to Evaluate the Effects of a Supplement on Energy and Mood

This study evaluates the effects of a Liposomal Magnesium Complex supplement on energy and mood. The study is a single-arm, virtual trial in which 60 adult participants consume the supplement daily for 14 days and complete self-reported questionnaires at multiple timepoints.

Study Overview

• Status: Completed
• Conditions: Stress; Mood
• Intervention / Treatment: Dietary supplement: Liposomal Magnesium Complex

• Study Type: Interventional
• Enrollment (Actual): 60
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Nevada
    • Las Vegas, Nevada, United States, 89118
      • Citruslabs

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Be male or female
• Be aged 18-60
• Anyone currently experiencing issues regarding all of the following: Low energy, Difficulty regulating mood
• Anyone who is generally healthy - does not live with any uncontrolled chronic disease.
• Anyone willing to avoid all other dietary supplements or products containing magnesium for the duration of the trial.
• Anyone willing to refrain from taking any products, prescription medications, or supplements that target energy, mood, stress, and sleep during the test period.
• Anyone willing to maintain their current diet, sleep schedule, and activity level for the duration of the study.
• Resides in the United States.

Exclusion Criteria:

• Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including cancer and mental health disorders.
• Anyone with a nut allergy or allergies or sensitivities to any of the product ingredients.
• Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period).
• Anyone who drinks heavily (i.e., 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men).
• History of diagnosed psychiatric or mood disorders.
• History of diagnosed sleep disorders.
• History of serious illness in the last three months.
• History of substance abuse.
• History of kidney disease.
• History of hormone or endocrine disorders, including but not limited to hypothyroidism, Hashimoto's thyroiditis, polycystic ovarian syndrome (PCOS), and diabetes.
• Planned surgery during the study period.
• Currently partaking in another research study or will be partaking in any other research study for the next 2 weeks, or at any point during this study's duration.
• Anyone unwilling to follow the study protocol.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Liposomal Magnesium Complex; Participants will consume one packet daily by squeezing the contents directly into the mouth.	Dietary supplement: Liposomal Magnesium Complex; The supplement is taken in the morning with the first meal of the day for 14 consecutive days.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in Energy Levels	Change in self-reported energy levels following daily use of the Liposomal Magnesium Complex supplement, assessed using participant questionnaires.	Baseline, Day 3, Day 7, Day 10, Day 14
Change in Mood	Change in self-reported mood following daily use of the Liposomal Magnesium Complex supplement, assessed using participant questionnaires.	Baseline, Day 3, Day 7, Day 10, Day 14

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in Stress Levels	Participant-reported changes in perceived stress levels assessed via questionnaire.	Baseline, Day 3, Day 7, Day 10, Day 14
Change in Relaxation and Calmness	Participant-reported changes in feelings of relaxation and calmness assessed via questionnaire.	Baseline, Day 3, Day 7, Day 10, Day 14
Change in Balanced Mood	Participant perception of mood balance assessed using self-reported questionnaires.	Baseline, Day 3, Day 7, Day 10, Day 14
Change in Sleep Quality	Participant-reported changes in sleep assessed via questionnaire.	Baseline, Day 3, Day 7, Day 10, Day 14
Change in Muscle Tension	Participant-reported changes in muscle tension assessed using questionnaires.	Baseline, Day 3, Day 7, Day 10, Day 14

Collaborators and Investigators

• Sponsor: Cymbiotika, LLC
• Collaborators: Citruslabs

Study record dates

Study Major Dates

• Study Start (Actual): October 14, 2025
• Primary Completion (Actual): December 8, 2025
• Study Completion (Actual): December 8, 2025

Study Registration Dates

• First Submitted: February 4, 2026
• First Submitted That Met QC Criteria: February 4, 2026
• First Posted (Actual): February 10, 2026

Study Record Updates

• Last Update Posted (Actual): February 10, 2026
• Last Update Submitted That Met QC Criteria: February 4, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Keywords: Sleep Quality; Magnesium
• Additional Relevant MeSH Terms: Nervous System Diseases; Mental Disorders; Sleep Wake Disorders; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Initiation and Maintenance Disorders
• Other Study ID Numbers: 20811

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No