- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07576413
Effects of Standing Desks and Intermittent Walking on Cognitive Fatigue
May 4, 2026 updated by: Clarkson University
Inter-individual Differences in the Effects of Sitting Desks, Standing Desks and Intermittent Walking on Cognitive Task Performance and Moods
The objective of this randomized-controlled crossover design was to identify inter-individual responses to the use of sitting desks, standing desks and two minutes of walking after twenty-eight minutes of sitting on the performance of cognitive tasks and moods in healthy undergraduate and graduate students.
Participants were randomly assigned to an order of interventions and were asked to perform 26 minutes of cognitive tasks followed by completing 2 minutes of surveys where they were asked about their moods.
Following the 28 minute cognitive battery participants were given a 2 minute break.
In the seated condition participants performed all tasks on a seated desk and had to remain seated for their 2 minute break.
In the standing condition participants performed the entire battery standing and had to remain standing for the 2 minute break.
In the intermittent walking condition, participants performed all tasks in a seated condition and for their 2 minute break, participants were asked to walk for 2 minutes at a pace that they felt comfortable.
Study Overview
Status
Completed
Intervention / Treatment
Detailed Description
The current protocol has been used by Boolani, et al, 2017 to induce cognitive fatigue in college age individuals between the ages of 18-45 to test the effectiveness of cocoa and caffeinated cocoa in attenuating fatigue.
It is our goal to explore the effects of standing desks as well as intermittent walking during cognitively fatiguing tasks and determine whether their use can attenuate mental fatigue in individuals between the ages of 18-45 years while performing cognitively challenging tasks.
Study Type
Interventional
Enrollment (Actual)
31
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
New York
-
Potsdam, New York, United States, 13699
- Clarkson University
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- 18-45 years in age
Exclusion Criteria:
- Use of any prescription medications for any chronic conditions
- current acute illness
- chronic illnesses
- color blindness
- inability to stand for 90 minutes
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Active Comparator: Sitting desk
Participants were asked to perform all tasks in a sitting condition
|
Participants performed a series of cognitive tasks on all 3 days
|
|
Experimental: Standing desk
Participants were asked to perform all tasks while standing
|
Participants performed a series of cognitive tasks on all 3 days
|
|
Experimental: Intermittent walking
Participants were asked to walk for 2 minutes at a self-selected pace after 28 minutes of performing tasks while seated.
|
Participants performed a series of cognitive tasks on all 3 days
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Profile of Mood Survey- Short Form Vigor on a 0 to 20 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the self-reported Profile of Mood Survey-Short Form participants reported their moods on the vigor scale of the POMS-SF
|
28 minutes, 58 minutes, 88 minutes
|
|
Profile of Mood Survey- Short Form Fatigue on a 0 to 20 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the self-reported Profile of Mood Survey-Short Form participants reported their moods on the fatigue scale of the POMS-SF
|
28 minutes, 58 minutes, 88 minutes
|
|
Profile of Mood Survey- Short Form Tension on a 0 to 20 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the self-reported Profile of Mood Survey-Short Form participants reported their moods on the tension scale of the POMS-SF
|
28 minutes, 58 minutes, 88 minutes
|
|
Profile of Mood Survey- Short Form Depression on a 0 to 20 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the self-reported Profile of Mood Survey-Short Form participants reported their moods on the depression scale of the POMS-SF
|
28 minutes, 58 minutes, 88 minutes
|
|
Profile of Mood Survey- Short Form Anger on a 0 to 20 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the self-reported Profile of Mood Survey-Short Form participants reported their moods on the anger scale of the POMS-SF
|
28 minutes, 58 minutes, 88 minutes
|
|
Changes on the Profile of Mood Survey- Short Form Confusion on a -4 to 16 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the self-reported Profile of Mood Survey-Short Form participants reported their moods on the confusion scale of the POMS-SF
|
28 minutes, 58 minutes, 88 minutes
|
|
Changes in state mental energy were measured on a 0 to 300 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the state mental and physical energy and fatigue scale participants reported their state mental energy.
|
28 minutes, 58 minutes, 88 minutes
|
|
Changes in state mental fatigue were measured on a 0 to 300 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the state mental and physical energy and fatigue scale participants reported their state mental fatigue.
|
28 minutes, 58 minutes, 88 minutes
|
|
Changes in state physical fatigue were measured on a 0 to 300 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the state mental and physical energy and fatigue scale participants reported their state physical fatigue.
|
28 minutes, 58 minutes, 88 minutes
|
|
Changes in state physical energy were measured on a 0 to 300 scale from baseline to the end of the study
Time Frame: 28 minutes, 58 minutes, 88 minutes
|
Using the state mental and physical energy and fatigue scale participants reported their state physical energy.
|
28 minutes, 58 minutes, 88 minutes
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Performance on the concentration task grid
Time Frame: 15 minutes, 45 minutes, 75 minutes
|
A 100 square grid was used as a measure of concentration.
The grid is arranged in a 10x10 square with each square containing a two-digit number (from 00 to 99) which are randomly placed in the center of each of the squares.
Participants were asked to mark off as many consecutive numbers as possible starting from 00 within a one-minute pe-riod, by tapping on the desired square
|
15 minutes, 45 minutes, 75 minutes
|
|
Performance on the continuous performance task
Time Frame: 6 minute, 36 minutes, 66 minutes
|
Participants monitored a continuous series of letters (A-Z; Tahoma Regular font, size 20 point) presented on the screen for 1000ms and were asked to respond to the detection of the letter "X" only when preceded by the letter "A" by tapping on the screen or press-ing the "Space" key.
|
6 minute, 36 minutes, 66 minutes
|
|
Performance on the distractor task
Time Frame: 16 minutes, 46 minutes, 76 minutes
|
Identify the correct responses on the distractor tasks
|
16 minutes, 46 minutes, 76 minutes
|
|
Performance on the Erikson Flanker task
Time Frame: 19 minutes, 49 minutes, 79 minutes
|
During this task participants were first presented with a white fixation cross for 200ms, followed immediately by five equally sized arrows arranged in a 10.5cm horizontal ar-ray for 800ms.
Participants were instructed to attend to the central arrow and ignore the four flankers.
Participants were asked to press the left key if the central arrow was fac-ing left and the right arrow if the central arrow was pointed to the right.
If all arrows were pointing the same direction (e.g.
"< < < < <") then the trial was considered con-gruent.
However, if the central arrow was pointing the opposite direction (e.g.
"> > < > >") then the trial was considered incongruent.
Subjects were presented with a 30 con-gruent and 30 incongruent trials in random order.
|
19 minutes, 49 minutes, 79 minutes
|
|
Performance on the Paced Visual Serial Addition Task
Time Frame: 17 minutes, 47 minutes, 77 minutes
|
Participants were asked to start at the number 0 and add the digit shown on the screen (0-9).
Participants were then asked to remember the previous number and add the next digit presented on the screen and type their responses on the keypad.
|
17 minutes, 47 minutes, 77 minutes
|
|
Performance on the serial subtraction three task
Time Frame: 2 minutes, 32 minutes, 62 minutes
|
Participants were asked to silently subtract backwards in threes from a ran-dom number starting between 800 and 999 that was presented on the iPad screen
|
2 minutes, 32 minutes, 62 minutes
|
|
Performance on the serial subtraction seven task
Time Frame: 4 minutes, 34 minutes, 64 minutes
|
Participants were asked to silently subtract backwards in sevens from a ran-dom number starting between 800 and 999 that was presented on the iPad screen
|
4 minutes, 34 minutes, 64 minutes
|
|
Performance on the Rapid Visual Input Processing Task
Time Frame: 14 minutes, 44 minutes, 74 minutes
|
Participants were required to monitor a continuous series of digits (1-9; Tahoma Regu-lar font, size 20point) presented on the screen every 1000ms.
The participants were given a primary, secondary, and tertiary task.
The participant's primary task was to detect the presentation of three consecutive odd digits that were in ascending order (e.g.
3-7-9), the secondary task was to detect three consecutive even digits that were in ascending order (e.g.
2-4-8), and the tertiary task was to identify the number 6 when it was presented on the screen.
|
14 minutes, 44 minutes, 74 minutes
|
|
Performance on the Stroops task
Time Frame: 18 minutes, 48 minutes, 78 minutes
|
Participants were presented words (Tahoma font, 20point), every 1000ms on a screen spelling the names of colors (i.e.
blue, yellow, red, green), which were either congru-ent (words presented in the same color as the color they were spelling out such as the RED presented in red font) or incongruent (words presented in a color different from the color that they spelled out such as the word RED spelled in green font).
Participants were presented with all five options of colors used in this test (red, green, yellow, black, and blue) and asked to press the color of the text (font color) and not the word presented on the screen.
There were 30 congruent and 30 incongruent tasks presented in random order and participants were scored on the number of correct responses, number of incorrect responses, and the average reaction time for correct responses.
Each test was scored separately for both congruent and incongruent tasks
|
18 minutes, 48 minutes, 78 minutes
|
|
Performance on the Perceptual Fast Counting Task
Time Frame: 20 minutes, 50 minutes, 80 minutes
|
Participants were asked to press the number key that qualified with the number of dots presented on the screen.
Each dot was approximately 0.5cm in diameter and the num-ber of dots on the screen ranged from 4 to 7. The number of dots was randomized across each trial and trials lasted 1 minute.
Participants were scored based on number of correct responses, average reaction time for each correct response and the total num-ber of trials conducted in one minute
|
20 minutes, 50 minutes, 80 minutes
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Ali Boolani, PhD, Clarkson University
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
June 1, 2018
Primary Completion (Actual)
December 15, 2018
Study Completion (Actual)
December 15, 2018
Study Registration Dates
First Submitted
May 4, 2026
First Submitted That Met QC Criteria
May 4, 2026
First Posted (Actual)
May 8, 2026
Study Record Updates
Last Update Posted (Actual)
May 8, 2026
Last Update Submitted That Met QC Criteria
May 4, 2026
Last Verified
May 1, 2026
More Information
Terms related to this study
Other Study ID Numbers
- 18-49.1
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
IPD Plan Description
Due to IRB restrictions no individual data will be shared with other researchers.
All data will be reported as aggregate.
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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