- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07602985
Evaluation of Different Patterns PHMM Root Tears
Evaluation Of Different Patterns Of Posterior Horn Medial Meniscus Root Tears
- To evaluate and classify different morphological patterns of posterior horn medial meniscus root tears (PHMMRTs) and assess their correlation with clinical presentation, MRI findings, and arthroscopic features.
- To determine the association between tear patterns and degree of meniscal extrusion.
- To evaluate the relationship between tear patterns and articular cartilage degeneration.
- To identify predictors of specific tear patterns based on clinical and radiological findings
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
The medial meniscus posterior horn root plays a pivotal role in maintaining normal knee biomechanics by converting axial loads into circumferential hoop stresses. Injury to this structure leads to loss of meniscal function, increased tibiofemoral contact pressure, and accelerated degeneration of articular cartilage, resembling the biomechanical effects of total meniscectomy.
Posterior horn medial meniscus root tears (PHMMRTs) present with various morphological patterns, including radial tears, oblique tears, complex tears, and complete root avulsions. Each tear pattern has distinct clinical, radiological, and arthroscopic characteristics, which may influence management strategies and prognosis. Despite increasing recognition of these injuries, data correlating tear patterns with clinical presentation and imaging findings remain limited.
Despite increasing recognition of PHMMRTs, limited studies have comprehensively correlated different tear patterns with clinical, radiological, and arthroscopic findings in a single prospective cohort. This study aims to fill this gap and provide clinically applicable correlations that may guide decision-making and prognosis assessment
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Ahmed Gamal Ahmed sayed, orthopedic resident
- Phone Number: +201003663138
- Email: ggemi800@gmail.com
Study Contact Backup
- Name: Hesham Abdelrahim Alkady, PROF
- Phone Number: +201005211797
- Email: hesham.elkadi@med.aun.edu.eg
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients aged ≥18 years (no upper age limit, as PHMMRTs are prevalent in elderly population)
- Clinical suspicion of medial meniscal injury
- MRI-confirmed posterior horn medial meniscus root tear
- Patients undergoing diagnostic or therapeutic knee arthroscopy
Exclusion Criteria:
- Previous surgical intervention to the affected knee
- Lateral meniscus root tears
- Advanced knee osteoarthritis (Kellgren-Lawrence grade IV)
- Inflammatory or rheumatoid arthritis
- Acute ligamentous injuries requiring immediate surgical intervention
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
different morphological patterns of posterior horn medial meniscus root tears.
Time Frame: Baseline
|
Identification and distribution of different morphological patterns of posterior horn medial meniscus root tears Using Magnetic Resonance Imaging (MRI)
|
Baseline
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Correlation between meniscal tear pattern and articular cartilage degeneration
Time Frame: Baseline
|
Assessment of the correlation between MRI -defined meniscal tear pattern and grade of articular cartilage degeneration assessed using Outerbridge classification
|
Baseline
|
Collaborators and Investigators
Sponsor
Investigators
- Study Director: Islam Karam Karam Allah, A PROF
Publications and helpful links
General Publications
- Lubowitz JH, Provencher MT, Poehling GG. Arthroscopy Techniques achieves PubMed Central citation, yet knee and shoulder outcome failures represent a challenge, and a presidential address prepares us for adversity. Arthroscopy. 2013 Sep;29(9):1461-2. doi: 10.1016/j.arthro.2013.06.012. No abstract available.
- Zhu JW, Zheng HL, Wang TF, Zhou ZY, Lei L, Guo XJ, Chen YX, Duan GQ. Global Research Trends on Medial Meniscus Posterior Root Tear: A 20-Year Bibliometric Analysis. J Multidiscip Healthc. 2025 Oct 9;18:6595-6605. doi: 10.2147/JMDH.S541028. eCollection 2025.
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- PHMM Root Tears
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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