- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07705854
Box Breathing Versus Foot Reflexology on Physiological and Psychological Stress Indicators in Emergency Physicians
July 10, 2026 updated by: Sara Mohamed Ali Arafa, Cairo University
This study aims to compare between the effect of box breathing and foot reflexology on physiological and psychological stress indicators in emergency physicians.
Study Overview
Status
Not yet recruiting
Conditions
Intervention / Treatment
Detailed Description
Healthcare workers are an especially vulnerable group, with stressful environments and work pressure often leading to burnout.
Long hours, overwork, shift work, inadequate staffing, emotional demands, are all believed to be contributors, and it has been suggested that stress and burnout have been associated with decreased job satisfaction, poor job performance, and negative patient outcomes.
Emergency physicians showed a high risk for developing burnout and work stress-related problems.
Emergency physicians report higher scores of emotional exhaustion and depersonalization when compared to other healthcare professionals.
The high flow of patients exceeding the teamwork capacity lead to excessive stressful working environment among the Egyptian emergency physicians rather than other emergency physicians in many Western countries.
Work-related stress have a negative impact on workers' health and safety.
This includes cardiovascular disease, gastrointestinal complaints, sleep troubles, mental health problems, fatigue, job dissatisfaction, accidents and injuries at work, reduced vigilance and job performance.
Box breathing exercise is a technique of slow breathing rhythm also known as square breathing used universally.
It increases the performance and concentration level; it also acts as a powerful stress relief.
Foot reflexology stimulates reflex zones in the foot that correspond to specific parts of the body, Reflex effects are known to release symptoms of stress by accelerating blood flow, diminishing tension, relaxing the mental state, increasing immunity, and improving the sense of well-being.
Therefore, the primary aim of this study will impact future researcher about the significance of the difference between box breathing and foot reflexology on physiological and psychological stress indicators in emergency physicians.
Study Type
Interventional
Enrollment (Estimated)
54
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Salma Ibrahim Al Ghitany, PhD
Study Contact Backup
- Name: Sara Mohamed Ali Arafa, B.Sc
- Phone Number: +20 11 13778146
- Email: sara3rafa96@gmail.com
Study Locations
-
-
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Cairo, Egypt
- EL-Zeiton district Hospitals
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Contact:
- Sara Mohamed Ali Arafa, B.Sc
- Phone Number: +20 11 13778146
- Email: sara3rafa96@gmail.com
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- Male emergency physicians aged 30-40 years.
- Body mass index (BMI) between 18.5 and 29.9 kg/m².
- Working 8-hour day shifts.
- Non-smokers.
- At least 1 year of professional experience.
- Able and willing to provide informed consent and comply with the study interventions and assessments.
Exclusion Criteria:
- Medical conditions that contraindicate participation in the interventions, including severe cardiovascular conditions or foot injuries that preclude foot reflexology.
- Use of medications that may affect hormonal or stress-related outcomes, including antidiabetic medications, thyroid medications, and antidepressants.
- Regular participation in stress-reduction techniques or relaxation programs.
- Working night shifts.
- BMI ≥30 kg/m² or <18.5 kg/m².
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Box Breathing Group
Participants will perform box breathing exercises daily for 4 weeks.
Each session will last 5 minutes and will be performed three times per day.
Participants will receive supervised sessions three days per week and will perform the remaining sessions as a home program.
The box breathing technique consists of inhaling for 4 seconds, holding the breath for 4 seconds, exhaling for 4 seconds, and holding the breath again for 4 seconds, repeated in cycles with scheduled rest periods.
|
Participants will perform box breathing exercises daily for 4 weeks.
Each session will last 5 minutes and will be performed three times per day.
Participants will receive supervised sessions three days per week and will perform the remaining sessions as a
|
|
Experimental: Foot Reflexology Group
Participants will receive foot reflexology sessions three times per week for 4 weeks.
Reflexology will be performed with the participant in a comfortable supine position and will include general stimulation of plantar reflex points followed by targeted pressure applied to the solar plexus and adrenal gland reflex areas of both feet.
|
Participants will receive foot reflexology sessions three times per week for 4 weeks.
Reflexology will be performed with the participant in a comfortable supine position and will include general stimulation of plantar reflex points followed by targeted pressure applied to the solar plexus and adrenal gland reflex areas of both feet.
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No Intervention: Control Group
Participants will not receive box breathing exercises or foot reflexology during the 4-week study period.
They will undergo the same baseline and post-intervention outcome assessments as the intervention groups.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Salivary Cortisol Level
Time Frame: 4 weeks
|
Change in salivary cortisol concentration (µg/dL) from baseline to the end of the 4-week intervention period.
Saliva samples will be collected before and after the intervention period and analyzed to determine changes in physiological stress.
|
4 weeks
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Heart Rate Variability (HRV)
Time Frame: 4 weeks
|
Change in heart rate variability from baseline to the end of the 4-week intervention period.
HRV will be assessed using the Welltory smartphone application as a physiological indicator of autonomic nervous system activity and stress.
|
4 weeks
|
|
Perceived Stress Scale (PSS)
Time Frame: 4 weeks
|
Change in perceived stress level from baseline to the end of the 4-week intervention period, assessed using the Perceived Stress Scale.
Total scores range from 0 to 40, with higher scores indicating greater perceived stress.
|
4 weeks
|
|
Maslach Burnout Inventory (MBI)
Time Frame: 4 weeks
|
Change in occupational burnout from baseline to the end of the 4-week intervention period, assessed using the Maslach Burnout Inventory, including the domains of Emotional Exhaustion, Depersonalization, and Personal Accomplishment.
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4 weeks
|
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Pittsburgh Sleep Quality Index (PSQI)
Time Frame: 4 weeks
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Change in sleep quality from baseline to the end of the 4-week intervention period, assessed using the Pittsburgh Sleep Quality Index.
Higher scores indicate poorer sleep quality.
|
4 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Director: Salma Ibrahim Al Ghitany, PhD, Lecturer, Cairo University
- Study Chair: Hany Ezzat Obaya, PhD, Professor, Cairo University
- Study Director: Mohamed Ahmed Khatab, PhD, Professor, Ain Shams University
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Estimated)
July 20, 2026
Primary Completion (Estimated)
September 20, 2026
Study Completion (Estimated)
September 30, 2026
Study Registration Dates
First Submitted
July 10, 2026
First Submitted That Met QC Criteria
July 10, 2026
First Posted (Actual)
July 15, 2026
Study Record Updates
Last Update Posted (Actual)
July 15, 2026
Last Update Submitted That Met QC Criteria
July 10, 2026
Last Verified
July 1, 2026
More Information
Terms related to this study
Other Study ID Numbers
- P.T.REC/012/006075
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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