- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07725861
Strain Counter Strain With and Without Sustained Natural Aphophyseal Glide in Non Specific Neck Pain
Effects of Strain Counter Strain With and Without Sustained Natural Aphophyseal Glide on Pain Range Of Motion ,Craniovertebral Angle and Disability in Patients With Non Specific Neck Pain
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Samrood Akram, PhD*
- Phone Number: 03324806143
- Email: samrood.akram@riphah.edu.pk
Study Contact Backup
- Name: Amna Zia, PhD*
- Phone Number: 03244686993
- Email: amna.zia@kemu.edu.pk
Study Locations
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Punjab Province
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Multan, Punjab Province, Pakistan
- Recruiting
- Ibne sina hospital and research institute.
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Contact:
- Sajad Rashid, MS-OMPT
- Phone Number: 0300 6309825
- Email: sajidch71@hotmail.com
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
•Both Males and Females (20)
- Age 18 and 60 years
- pain intensity 3-6 rating on NPRS
- Pain localized to cervical or upper trapezius
Exclusion Criteria:
• Cervical radiculopathy(20)
- History of whiplash injury
- History of cervical and thoracic spine surgery
- Neck pain associated with vertigo(20)
- History of spinal osteoporosis
- Vertebral Fractures
- Tumours
- Diagnosed psychological disorders
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
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Experimental: Strain Counterstrain + SNAG with Common Treatment
Strain-Counterstrain (SCS) and SNAGs (Sustained Natural Apophyseal Glides) are two highly effective, non-invasive manual therapy techniques used to relieve neck pain.
SCS gently relaxes hyperactive muscles by placing the body in a pain-free position, while SNAGs are movement-based mobilizations that restore joint function and reduce pain
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Group A (Experimental Group) will receive both Strain Counterstrain (SCS) and SNAGs (30).
They will attend 12 sessions in total, three times per week for four weeks.
First, the SCS technique will be applied to the upper trapezius, levator scapulae, and scalene muscles.
The patient will lie on their back or side while the therapist finds tender points and positions the neck to reduce tension, holding that position for 90 seconds before gently returning it to neutral and checking for pain.
After this, SNAGs (Sustained Natural Apophyseal Glides) will be applied, targeting spinal segments like C2-C3 for rotation and C5-C6 for flexion or extension.
While the patient sits upright, the therapist will apply a sustained glide on the vertebra as the patient moves the neck in the limited direction.
Each movement will be repeated 6-10 times and followed by a reassessment
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Active Comparator: Strain Counterstain (SCS) only
Strain-Counterstrain (SCS) is a gentle, passive osteopathic technique that treats neck pain by finding tender points and holding the neck in a highly specific "position of ease" for 90 seconds.
This shortens the affected, spasming muscle, allowing the nervous system to reset muscle spindles and break the pain
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Group B (Control Group) will receive only the Strain Counterstrain (SCS) technique without SNAGs (31).
The same neck muscles will be targeted, and the patient will lie in a similar position while the therapist identifies tender points and performs the SCS technique.
No joint glides or mobilization will be applied in this group.
Both groups will receive a total of 12 sessions over four weeks, with each session lasting about 40 minutes.
Pre- and post-treatment assessments will be carried out to measure changes in pain (using NPRS/VAS), cervical ROM, craniovertebral angle (CVA), and neck-related disability (using the Neck Disability Index - NDI).
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Numeric pain rate scale (NPRS)
Time Frame: upto 4 weeks
|
Patient level of pain will be assessed using this scale.
This scale ranges from 0 to 10. 0 indicates "no pain" and 10 indicates "worst pain".(25)
NPRS shows strong construct validity and correlates well with other pain scales like the Visual Analog Scale (VAS) and McGill Pain Questionnaire.
It is especially useful for tracking changes in pain over time.(13)
The NPRS demonstrates excellent test-retest reliability with an intraclass correlation coefficient (ICC) of ~0.95 in patients with chronic musculoskeletal pain.(26)
The MCID for NPRS is generally considered to be 2 points, meaning a change of 2 or more points is considered clinically meaningful in musculoskeletal pain patients
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upto 4 weeks
|
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Neck Disability index (NDI)
Time Frame: Upto 4 weeks
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This questionnaire will be used to assess disability.
It comprises of 10 items; 7 related to daily living activities, 2 related to pain and 1 related to concentration.
Each item is scored from 0 to 5. Total score is expressed as a percentage, with higher scores related to greater disability(28) Its construct validity has been supported through correlations with pain intensity, cervical range of motion, and quality-of-life measures (13).
It shows excellent test retest reliability, with an ICC of 0.89-0.98 in patients with mechanical or non-specific neck pain (26)The Minimal Detectable Change (MDC) for NDI has been reported to be 5 points, while the MCID is commonly considered to be around 7-10 points for clinical relevance in chronic musculoskeletal pain
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Upto 4 weeks
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Universal Goniometer (UG)
Time Frame: Upto 4 weeks
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It will measure range of motion of neck (29) A universal goniometer will be used to measure active cervical range of motion (CROM) in flexion, extension, lateral flexion, and rotation. This tool is portable, affordable, and easy to use in clinical and research settings. The validity of goniometry in measuring cervical ROM has been confirmed through comparisons with CROM devices and motion sensors, showing strong correlations (r > 0.85) in neck mobility measurement (27). Goniometer-based cervical ROM assessments demonstrate good to excellent reliability, with ICC values ranging from 0.79 to 0.96, depending on the plane of movement and rater experience |
Upto 4 weeks
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Craniovertebral Angle (CVA)
Time Frame: Upto 4 weeks
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It is used to measure the degree of forward head posture, which is common in people with neck pain.
A smaller CVA indicates a more forward head position, while a larger angle reflects a more neutral, healthy posture .To measure CVA, a lateral photograph is taken while the patient stands in a relaxed position.
The angle is formed between a horizontal line passing through the C7 vertebra and a line connecting C7 to the tragus of the ear.
This measurement is usually done using image analysis software or mobile applications like Posture Screen or ImageJ.
Studies have shown that CVA measurement is a reliable and valid method for assessing head posture.
It has good intra-rater and inter-rater reliability, with Intraclass Correlation Coefficients (ICC) ranging from 0.88 to 0.98 (8, 15).The Minimal Detectable Change (MDC) for CVA varies across studies but is generally estimated to be about 3-4 degrees, making it a sensitive tool for detecting postural improvements
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Upto 4 weeks
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Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Amna Zia, PhD*, Riphah International University, Lahore
- Principal Investigator: Hadeel Mukhtar, Riphah International University, Lahore
Publications and helpful links
General Publications
- Blanpied PR, Gross AR, Elliott JM, Devaney LL, Clewley D, Walton DM, Sparks C, Robertson EK. Neck Pain: Revision 2017. J Orthop Sports Phys Ther. 2017 Jul;47(7):A1-A83. doi: 10.2519/jospt.2017.0302.
- Bernal-Utrera C, Gonzalez-Gerez JJ, Anarte-Lazo E, Rodriguez-Blanco C. Manual therapy versus therapeutic exercise in non-specific chronic neck pain: a randomized controlled trial. Trials. 2020 Jul 28;21(1):682. doi: 10.1186/s13063-020-04610-w.
- Cerezo-Tellez E, Torres-Lacomba M, Mayoral-Del-Moral O, Pacheco-da-Costa S, Prieto-Merino D, Sanchez-Sanchez B. Health related quality of life improvement in chronic non-specific neck pain: secondary analysis from a single blinded, randomized clinical trial. Health Qual Life Outcomes. 2018 Nov 6;16(1):207. doi: 10.1186/s12955-018-1032-6.
- Raja G P, Bhat N S, Fernandez-de-Las-Penas C, Gangavelli R, Davis F, Shankar R, Prabhu A. Effectiveness of deep cervical fascial manipulation and yoga postures on pain, function, and oculomotor control in patients with mechanical neck pain: study protocol of a pragmatic, parallel-group, randomized, controlled trial. Trials. 2021 Aug 28;22(1):574. doi: 10.1186/s13063-021-05533-w.
- de Koning CH, van den Heuvel SP, Staal JB, Smits-Engelsman BC, Hendriks EJ. Clinimetric evaluation of active range of motion measures in patients with non-specific neck pain: a systematic review. Eur Spine J. 2008 Jul;17(7):905-21. doi: 10.1007/s00586-008-0656-3. Epub 2008 Apr 22.
- Barbosa-Silva J, Luc A, Sobral de Oliveira-Souza AI, Martins de Abreu R, Cipriano J, de Schaetzen M, Pitance L, Armijo-Olivo S. The Effectiveness of Mulligan's Techniques in Non-Specific Neck Pain: A Systematic Review and Meta-Analysis. Physiother Res Int. 2025 Jul;30(3):e70045. doi: 10.1002/pri.70045.
- Shukla Yu, Shah D. Effect of Craniocervical Flexion Training in Mechanical Neck Pain on Proprioception, Endurance and Pain -An Interventional Study. International Journal of Health Research. 2020;Vol.5:565.
- Shamsi S, Alyazedi FM, Abdelkader SM, Khan S, Akhtar A. Efficacy of Sustained Natural Apophyseal Glides in the Management of Mechanical Neck Pain: A Randomized Clinical Trial. Indian Journal of Medical Specialities. 2021;12(4):199-206.
- Al Shehri A, Khan S, Shamsi S, Almureef SS. Comparative study of mulligan (snags) and maitland mobilization in neck pain. European Journal of Physical Education and Sport Science. 2018.
- Prayerna B, SuBBiah K, Asser P, MiLaneSe S. Effectiveness of mulligan's sustained natural apophyseal glide (SNAG) over first rib in reducing pain and improving cervical rotation in individuals with mechanical neck dysfunction. Journal of Clinical & Diagnostic Research. 2019;13(3)
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- REC/RCR&AHS/25/0133 Hadeel
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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