Management of Early Onset Scoliosis by Active Apex Correction Technique

July 23, 2026 updated by: Mahmoud Gaber Elsayed, Al-Azhar University
Early onset scoliosis is challenging cases in management .different techniques used to correct the deformity ranging between fusionlees and fusion surgery. Fusionless surgery permits developments of vertebral column and lung to avoid thoracic insufficiency syndrome. Fusion surgeries for complicated and high curves .New fusionless technique that I will use in my research is to modulate and guide the growth of the Apex of deformity through tethering the convex side and modulate the concave side and follow up the patients to see the results on their radiological and clinical parameters.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

15

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Egypt
    • Asyut Governorate
      • Asyut, Asyut Governorate, Egypt, 71524

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • patients with early-onset scoliosis below 10 years
  • patients not operated on before.

Exclusion Criteria:

  • Patients above 10 years.
  • Patients operated on before

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Surgery
Procedure: Active Apex correction of scoliotic deformity
Tethering the convex side of Apex and modulation of the concave side .proximal and distal anchoring screws. Dominos between rods to slide and permits the growth of the vertebral column

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in major coronal Cobb angle
Time Frame: Baseline to 12 months after Active Apex Correction (APC) surgery
Radiographic correction of the primary scoliotic curve measured as the change in the major coronal Cobb angle (degrees) on standing posteroanterior whole-spine radiographs
Baseline to 12 months after Active Apex Correction (APC) surgery

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in thoracic spinal growth
Time Frame: Baseline to 12 months
Change in T1-T12 spinal height (mm) measured on standing whole-spine radiographs.
Baseline to 12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Al-Azhar University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 25, 2023

Primary Completion (Estimated)

October 11, 2026

Study Completion (Estimated)

January 2, 2027

Study Registration Dates

First Submitted

November 19, 2023

First Submitted That Met QC Criteria

July 23, 2026

First Posted (Actual)

July 27, 2026

Study Record Updates

Last Update Posted (Actual)

July 27, 2026

Last Update Submitted That Met QC Criteria

July 23, 2026

Last Verified

July 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • MEOSAPCT

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Contact through my phone number or my email

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Cases of Early Onset Scoliosis

Clinical Trials on Active Apex correction of scoliotic deformity

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Vietnam

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe