Search clinical trials for: Esketamine

Total 1301 results

Erasmus Medical Center

Enrolling by invitation

Long-term Pain Modulation by Intravenous Esketamine in CRPS (KetCRPS-2)

Complex Regional Pain Syndromes | CRPS (Complex Regional Pain Syndromes)

Netherlands
Janssen Research & Development, LLC

Completed

Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users

Drug Abuse

United States
Medical University of Vienna

Recruiting

Imaging Neural Correlates of Ketamine Using PET/MR (RSKet)

Major Depressive Disorder

Austria
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression (SYNAPSE)

Treatment Resistant Depressive Disorder

United States, Japan, Belgium
Qinghai University
Qinghai Red Cross Hospital

Not yet recruiting

Effects of Esketamine on Postpartum Depression (EEPD)

Postpartum Depression
Dr. Inge Winter
Universität Münster

Not yet recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Italy, Germany, Spain, United Kingdom
Fujian Provincial Hospital

Completed

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Postoperative Recovery

China
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression

Depression

Japan
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression

Major Depressive Disorder

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression

Bipolar Depression

Poland
Tianjin Medical University General Hospital

Recruiting

S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture

Postoperative Pain | Postoperative Cognitive Dysfunction

China
The George Institute
The University of New South Wales

Not yet recruiting

Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression (TREK)

Treatment Resistant Depression

Australia
Second Affiliated Hospital, School of Medicine,...

Recruiting

Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery

Postoperative Hyperalgesia

China
Beijing Obstetrics and Gynecology Hospital
Obstetrics & Gynecology Hospital of Fudan University; Beijing Haidian Maternal... and other collaborators

Unknown

The Efficacy and Safety of S-ketamine in Elective Cesarean Section (ES-CS)

Depression | Analgesia | Cesarean Section | Anesthesia | Parturition
Zylorion Health

Withdrawn

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study (ZYL-730-02)

Treatment Resistant Major Depressive Disorder
Eye & ENT Hospital of Fudan University

Recruiting

Comparison of Esketamine-Propofol and Fentanyl-Propofol

Hemodynamics

China
Centre Hospitalier Universitaire de Charleroi
Centre Hospitalier Universitaire de Liege

Recruiting

Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome. (KESK-FIQ)

Fibromyalgia

Belgium
Zylorion Health

Terminated

Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression (ZYL-730-01)

Treatment Resistant Major Depressive Disorder

Canada
Janssen Research & Development, LLC

Completed

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
Janssen Research & Development, LLC

Completed

A Mass Balance Study With a Microtracer Dose of 14C-esketamine in Healthy Male Participants

Healthy

United States
Anqing Municipal Hospital

Completed

Esketamine Administration on Recovery Quality After Radical Mastectomy

Esketamine and the Quality of Recovery

China
Association pour la Formation l'Enseignement et...

Recruiting

Tolerance Assesment of the Usage of an Analgesic Dose of Esketamine for Treatment of Moderate to Intense Pain in an Emergency Departement (ESKETAMINE)

Pain, Acute

France
Chinese PLA General Hospital
First Affiliated Hospital, Sun Yat-Sen University; Shengjing Hospital; First... and other collaborators

Not yet recruiting

Safety and Efficacy Evaluation of S (+) - Ketamine in Adults

Postoperative Pain | Anesthesia | Adults
Chinese PLA General Hospital
Shanghai Children's Medical Center; Beijing Children's Hospital; Southern Medical... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of S (+) - Ketamine in Children

Delirium | Postoperative Pain | Analgesia | Children | Acute Pain | Depression, Anxiety | Hyperalgesia | S-ketamine | Esketamine

China
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetic Study of Inhaled Esketamine in Healthy Volunteers

Healthy Volunteers

Poland
bo xu

Not yet recruiting

Effect of Subanesthetic Dose Esketamine on Propofol-refentanil Closed-loop Targeted Controlled Infusion

Esketamine
Psych Atlanta

Completed

Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine

Treatment Resistant Depression

United States
Janssen Research & Development, LLC

Completed

A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant Depression (SUSTAIN-3)

Depressive Disorder, Treatment-Resistant

United States, France, Poland, United Kingdom, Belgium, Germany, Taiwan, Spain, Argentina, Mexico, Bulgaria, Malaysia, South Africa, Turkey, Canada, Korea, Republic of, Brazil, Estonia, Hungary, Lithuania, Slovakia, Sweden, Czechia, A... and more
Lukas Pezawas

Recruiting

Add-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine Spray (Esketamin+)

Major Depressive Disorder | Therapy Resistant Depression

Austria
Janssen Research & Development, LLC

Completed

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

Major Depressive Disorder

United States
Yan Qiu

Unknown

The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT) (ECT)

Major Depressive Disorder | Depression, Unipolar | Depression, Bipolar | Manic-Depressive - Now Depressed

China
Lund University

Completed

Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy Volunteers

Healthy | Abnormal Vascular Flow

Sweden
Wuhan Union Hospital, China

Recruiting

Immunoinflammatory Regulation of Esketamine in Septic Patients

Sepsis | Inflammatory Response | Immunosuppression | Esketamine

China
Zhuan Zhang

Completed

Effect of Subanesthetic Dose of Esketamine on Sleep Quality and Recovery of Gastrointestinal Function in Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery in the Early Postoperative Period

Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery

China
Medical University Innsbruck

Withdrawn

ECT vs. Esketamine (ETES)

Major Depressive Disorder | Treatment Resistant Depression

Austria
Janssen Research & Development, LLC

Completed

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly and and Healthy Younger Adult Participants

Healthy

Belgium
Turku University Hospital
University of Turku; University of Helsinki

Completed

Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients (DoseRespKeta)

Pain, Postoperative

Finland
Yangzhou University

Not yet recruiting

Application of Different Modes of Esketamine Administration in Pediatric Day Circumcision

Pain
Royal North Shore Hospital
Janssen-Cilag Pty Ltd

Recruiting

Positioning of Esketamine Treatment in the Real-world Management of Depression (PoET)

Major Depressive Disorder

Australia
University Hospital, Basel, Switzerland

Completed

Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine

Pain

Switzerland
Air Force Military Medical University, China

Not yet recruiting

ED50 of Esketamine for Laser Treatment in Children (ESCALATE)

Anesthesia
Wuhan Union Hospital, China

Not yet recruiting

Prophylactic Effects of Esketamine in Surgical Patients

Surgical Injury

China
Second Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Effect of Esketamine on 95% Induction Dose of Remimazolam (EEIDR)

Sedation | Pediatric | Gastroscopy | ED95

China
Peking University First Hospital
Peking University International Hospital; Women's Hospital School Of Medicine... and other collaborators

Completed

Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression

Postpartum Depression | Ketamine | Prenatal Depression

China
Peking University First Hospital
Peking University International Hospital; Women's Hospital School Of Medicine... and other collaborators

Completed

Low-dose S-ketamine in Women With Prenatal Depression

Postpartum Depression | Ketamine | Prenatal Depression

China
Children's Hospital of Fudan University

Recruiting

Esketamine for the Treatment of Rett Syndrome

Rett Syndrome

China
Eye & ENT Hospital of Fudan University

Completed

S-ketamin Premedication in Pediatric EENT Surgery

Pain, Procedural | Emotions | Separation Anxiety

China
Reinier de Graaf Groep

Recruiting

Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study (EASYlight)

Endometriosis | Chronic Pelvic Pain Syndrome

Netherlands
University of North Carolina, Chapel Hill

Recruiting

Brain Network Dynamics of Depression During Esketamine Treatment (K-BRAINED)

Depressive Disorder, Major

United States

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