Mirror Therapy in Children With Hemiparetic Cerebral Palsy
Effects of Mirror Therapy on Upper Extremity Function and Motor Control in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder that frequently impairs upper extremity motor control and hand function, resulting in limitations in daily activities. Mirror therapy is a low-cost, easy-to-implement intervention that promotes motor learning by stimulating cortical reorganization and neuroplasticity. This randomized, sham-controlled clinical trial aims to investigate the effects of mirror therapy on upper extremity function, selective motor control, hand function, hand grip strength, and manual dexterity in children with hemiparetic CP.
Twenty-six children with hemiparetic CP will be randomly assigned to either an experimental group receiving mirror therapy combined with conventional physiotherapy or a control group receiving sham mirror therapy combined with the same conventional physiotherapy program. The intervention will be administered over an 8-week period.
Baseline assessments will include the Manual Ability Classification System (MACS) and the Modified Ashworth Scale. Outcome measures collected before and after the intervention will include the Selective Control of the Upper Extremity Scale (SCUES), ABILHAND-Kids questionnaire, hand grip strength measured with the Jamar dynamometer, and manual dexterity assessed using the Nine-Hole Peg Test.
The study is expected to provide evidence regarding the effectiveness of mirror therapy beyond conventional physiotherapy by using a sham-controlled design and to contribute to the development of standardized, evidence-based rehabilitation protocols for improving upper extremity function in children with hemiparetic CP.
Study Overview
Status
Intervention / Treatment
Detailed Description
Cerebral palsy (CP) is a non-progressive neurodevelopmental disorder resulting from injury to the developing brain and is characterized by impairments in movement, posture, and motor function. Children with hemiparetic CP commonly experience unilateral upper extremity weakness, impaired selective motor control, reduced hand function, decreased grip strength, and limitations in activities of daily living. These impairments negatively affect functional independence and quality of life.
Mirror therapy is a low-cost, non-invasive rehabilitation approach based on the principles of neuroplasticity and motor learning. By creating the visual illusion that the affected upper limb is moving normally through the reflection of the unaffected limb, mirror therapy is thought to enhance cortical activation and facilitate motor recovery. Although originally developed for phantom limb pain, mirror therapy has been increasingly applied in neurological rehabilitation and has demonstrated promising effects on upper extremity function.
Several studies have investigated mirror therapy in children with cerebral palsy and reported improvements in hand function and motor performance. However, considerable variation exists in treatment protocols, including intervention duration, exercise content, and comparison groups, limiting the generalizability of the findings. In addition, few studies have incorporated a sham-controlled design, making it difficult to distinguish the specific therapeutic effects of mirror therapy from nonspecific treatment effects.
The present randomized, sham-controlled clinical trial aims to evaluate the effectiveness of mirror therapy combined with conventional physiotherapy in children with hemiparetic CP. Participants will be randomly assigned to either an experimental group receiving mirror therapy in addition to conventional physiotherapy or a control group receiving sham mirror therapy together with the same conventional physiotherapy program.
Upper extremity outcomes will be evaluated before and after an 8-week intervention period using validated assessment tools, including the Selective Control of the Upper Extremity Scale (SCUES), ABILHAND-Kids questionnaire, hand grip strength measured with a Jamar dynamometer, and manual dexterity assessed with the Nine-Hole Peg Test. Baseline motor ability and muscle tone will be documented using the Manual Ability Classification System (MACS) and the Modified Ashworth Scale.
This study is expected to provide higher-quality evidence regarding the effectiveness of mirror therapy by using a standardized intervention protocol and a sham-controlled design. The findings may contribute to the development of evidence-based rehabilitation strategies aimed at improving upper extremity motor control, hand function, and functional independence in children with hemiparetic CP.
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: İrem Çetinkaya, PhD
- Phone Number: 5548056805
- Email: iremkaranki@gmail.com
Study Contact Backup
- Name: Emine Kılıç
- Phone Number: 5304936253
- Email: fzt.eminekilic@gmail.com
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Diagnosis of hemiparetic cerebral palsy
- Aged between 6 and 12 years
- Manual Ability Classification System (MACS) level I-III
- Having received or currently receiving physiotherapy and rehabilitation for at least 6 months
Exclusion Criteria:
- Cognitive or communication impairments that would prevent participation in mirror therapy.
- Inability to cooperate with the assessment or intervention procedures.
- Presence of uncontrolled neurological disorders, such as epilepsy.
- Musculoskeletal deformities or a history of upper extremity surgery.
- Visual or hearing impairments that would interfere with participation in mirror therapy.
- Receipt of upper extremity interventions other than routine physiotherapy (e.g., botulinum toxin injection or surgical intervention) within the past 6 months.
Inability to comply with the study assessment or intervention schedule.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Mirror Group
Participants assigned to the experimental group will receive an individualized neurodevelopmental treatment-based conventional physiotherapy program combined with mirror therapy, twice weekly for 8 weeks.
|
Mirror therapy will be administered for approximately 20 minutes following conventional physiotherapy sessions, twice weekly for 8 weeks.
During the intervention, participants will perform bilateral, symmetrical upper extremity movements while observing the mirror reflection of the unaffected upper limb to create the visual illusion of movement of the affected limb.
Individualized neurodevelopmental treatment-based physiotherapy including stretching, upper extremity strengthening exercises, mat activities, standing and gait training, and fine motor skill activities.
The program will be delivered for approximately 40 minutes per session, twice weekly for 8 weeks.
|
|
Sham Comparator: Control Group
Participants assigned to the control group will receive the same individualized neurodevelopmental treatment-based conventional physiotherapy program combined with sham mirror therapy, twice weekly for 8 weeks.
|
Individualized neurodevelopmental treatment-based physiotherapy including stretching, upper extremity strengthening exercises, mat activities, standing and gait training, and fine motor skill activities.
The program will be delivered for approximately 40 minutes per session, twice weekly for 8 weeks.
Sham mirror therapy will be administered for approximately 20 minutes following conventional physiotherapy sessions, twice weekly for 8 weeks.
Participants will perform the same bilateral upper extremity exercises while the mirror is positioned to eliminate visual mirror feedback.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Change in Selective Motor Control of the Upper Extremity
Time Frame: Baseline and after the 8-week intervention
|
Selective motor control of the affected upper extremity will be assessed using the Selective Control of the Upper Extremity Scale (SCUES).
The scale evaluates selective voluntary movement at the shoulder, elbow, forearm, wrist, and fingers.
Higher scores indicate better selective motor control.
|
Baseline and after the 8-week intervention
|
|
Change in Manual Dexterity
Time Frame: Baseline and after the 8-week intervention
|
Manual dexterity will be assessed using the Nine-Hole Peg Test (9-HPT).
The test measures the time required to place and remove nine pegs using the affected hand.
Shorter completion times indicate better manual dexterity.
|
Baseline and after the 8-week intervention
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Change in Manual Ability in Daily Activities
Time Frame: Baseline and after the 8-week intervention
|
Manual ability in daily activities will be assessed using the ABILHAND-Kids questionnaire.
The questionnaire evaluates the child's perceived difficulty in performing everyday bimanual activities.
Higher scores indicate better manual ability.
|
Baseline and after the 8-week intervention
|
|
Change in Hand Grip Strength
Time Frame: Baseline and after the 8-week intervention
|
Hand grip strength of the affected hand will be assessed using a Jamar hand dynamometer.
Grip strength will be recorded in kilograms.
Higher values indicate greater hand grip strength.
|
Baseline and after the 8-week intervention
|
Collaborators and Investigators
Sponsor
Collaborators
Investigators
- Study Director: İrem Çetinkaya, PhD, Marmara University
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- karanki9
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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