Mirror Therapy in Children With Hemiparetic Cerebral Palsy
Effects of Mirror Therapy on Upper Extremity Function and Motor Control in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder that frequently impairs upper extremity motor control and hand function, resulting in limitations in daily activities. Mirror therapy is a low-cost, easy-to-implement intervention that promotes motor learning by stimulating cortical reorganization and neuroplasticity. This randomized, sham-controlled clinical trial aims to investigate the effects of mirror therapy on upper extremity function, selective motor control, hand function, hand grip strength, and manual dexterity in children with hemiparetic CP.
Twenty-six children with hemiparetic CP will be randomly assigned to either an experimental group receiving mirror therapy combined with conventional physiotherapy or a control group receiving sham mirror therapy combined with the same conventional physiotherapy program. The intervention will be administered over an 8-week period.
Baseline assessments will include the Manual Ability Classification System (MACS) and the Modified Ashworth Scale. Outcome measures collected before and after the intervention will include the Selective Control of the Upper Extremity Scale (SCUES), ABILHAND-Kids questionnaire, hand grip strength measured with the Jamar dynamometer, and manual dexterity assessed using the Nine-Hole Peg Test.
The study is expected to provide evidence regarding the effectiveness of mirror therapy beyond conventional physiotherapy by using a sham-controlled design and to contribute to the development of standardized, evidence-based rehabilitation protocols for improving upper extremity function in children with hemiparetic CP.
Przegląd badań
Status
Warunki
Interwencja / Leczenie
Szczegółowy opis
Cerebral palsy (CP) is a non-progressive neurodevelopmental disorder resulting from injury to the developing brain and is characterized by impairments in movement, posture, and motor function. Children with hemiparetic CP commonly experience unilateral upper extremity weakness, impaired selective motor control, reduced hand function, decreased grip strength, and limitations in activities of daily living. These impairments negatively affect functional independence and quality of life.
Mirror therapy is a low-cost, non-invasive rehabilitation approach based on the principles of neuroplasticity and motor learning. By creating the visual illusion that the affected upper limb is moving normally through the reflection of the unaffected limb, mirror therapy is thought to enhance cortical activation and facilitate motor recovery. Although originally developed for phantom limb pain, mirror therapy has been increasingly applied in neurological rehabilitation and has demonstrated promising effects on upper extremity function.
Several studies have investigated mirror therapy in children with cerebral palsy and reported improvements in hand function and motor performance. However, considerable variation exists in treatment protocols, including intervention duration, exercise content, and comparison groups, limiting the generalizability of the findings. In addition, few studies have incorporated a sham-controlled design, making it difficult to distinguish the specific therapeutic effects of mirror therapy from nonspecific treatment effects.
The present randomized, sham-controlled clinical trial aims to evaluate the effectiveness of mirror therapy combined with conventional physiotherapy in children with hemiparetic CP. Participants will be randomly assigned to either an experimental group receiving mirror therapy in addition to conventional physiotherapy or a control group receiving sham mirror therapy together with the same conventional physiotherapy program.
Upper extremity outcomes will be evaluated before and after an 8-week intervention period using validated assessment tools, including the Selective Control of the Upper Extremity Scale (SCUES), ABILHAND-Kids questionnaire, hand grip strength measured with a Jamar dynamometer, and manual dexterity assessed with the Nine-Hole Peg Test. Baseline motor ability and muscle tone will be documented using the Manual Ability Classification System (MACS) and the Modified Ashworth Scale.
This study is expected to provide higher-quality evidence regarding the effectiveness of mirror therapy by using a standardized intervention protocol and a sham-controlled design. The findings may contribute to the development of evidence-based rehabilitation strategies aimed at improving upper extremity motor control, hand function, and functional independence in children with hemiparetic CP.
Typ studiów
Zapisy (Szacowany)
Faza
- Nie dotyczy
Kontakty i lokalizacje
Kontakt w sprawie studiów
- Nazwa: İrem Çetinkaya, PhD
- Numer telefonu: 5548056805
- E-mail: iremkaranki@gmail.com
Kopia zapasowa kontaktu do badania
- Nazwa: Emine Kılıç
- Numer telefonu: 5304936253
- E-mail: fzt.eminekilic@gmail.com
Kryteria uczestnictwa
Kryteria kwalifikacji
Wiek uprawniający do nauki
- Dziecko
Akceptuje zdrowych ochotników
Opis
Inclusion Criteria:
- Diagnosis of hemiparetic cerebral palsy
- Aged between 6 and 12 years
- Manual Ability Classification System (MACS) level I-III
- Having received or currently receiving physiotherapy and rehabilitation for at least 6 months
Exclusion Criteria:
- Cognitive or communication impairments that would prevent participation in mirror therapy.
- Inability to cooperate with the assessment or intervention procedures.
- Presence of uncontrolled neurological disorders, such as epilepsy.
- Musculoskeletal deformities or a history of upper extremity surgery.
- Visual or hearing impairments that would interfere with participation in mirror therapy.
- Receipt of upper extremity interventions other than routine physiotherapy (e.g., botulinum toxin injection or surgical intervention) within the past 6 months.
Inability to comply with the study assessment or intervention schedule.
Plan studiów
Jak projektuje się badanie?
Szczegóły projektu
- Główny cel: Leczenie
- Przydział: Randomizowane
- Model interwencyjny: Przydział równoległy
- Maskowanie: Podwójnie
Broń i interwencje
Grupa uczestników / Arm |
Interwencja / Leczenie |
|---|---|
|
Eksperymentalny: Mirror Group
Participants assigned to the experimental group will receive an individualized neurodevelopmental treatment-based conventional physiotherapy program combined with mirror therapy, twice weekly for 8 weeks.
|
Mirror therapy will be administered for approximately 20 minutes following conventional physiotherapy sessions, twice weekly for 8 weeks.
During the intervention, participants will perform bilateral, symmetrical upper extremity movements while observing the mirror reflection of the unaffected upper limb to create the visual illusion of movement of the affected limb.
Individualized neurodevelopmental treatment-based physiotherapy including stretching, upper extremity strengthening exercises, mat activities, standing and gait training, and fine motor skill activities.
The program will be delivered for approximately 40 minutes per session, twice weekly for 8 weeks.
|
|
Pozorny komparator: Control Group
Participants assigned to the control group will receive the same individualized neurodevelopmental treatment-based conventional physiotherapy program combined with sham mirror therapy, twice weekly for 8 weeks.
|
Individualized neurodevelopmental treatment-based physiotherapy including stretching, upper extremity strengthening exercises, mat activities, standing and gait training, and fine motor skill activities.
The program will be delivered for approximately 40 minutes per session, twice weekly for 8 weeks.
Sham mirror therapy will be administered for approximately 20 minutes following conventional physiotherapy sessions, twice weekly for 8 weeks.
Participants will perform the same bilateral upper extremity exercises while the mirror is positioned to eliminate visual mirror feedback.
|
Co mierzy badanie?
Podstawowe miary wyniku
Miara wyniku |
Opis środka |
Ramy czasowe |
|---|---|---|
|
Change in Selective Motor Control of the Upper Extremity
Ramy czasowe: Baseline and after the 8-week intervention
|
Selective motor control of the affected upper extremity will be assessed using the Selective Control of the Upper Extremity Scale (SCUES).
The scale evaluates selective voluntary movement at the shoulder, elbow, forearm, wrist, and fingers.
Higher scores indicate better selective motor control.
|
Baseline and after the 8-week intervention
|
|
Change in Manual Dexterity
Ramy czasowe: Baseline and after the 8-week intervention
|
Manual dexterity will be assessed using the Nine-Hole Peg Test (9-HPT).
The test measures the time required to place and remove nine pegs using the affected hand.
Shorter completion times indicate better manual dexterity.
|
Baseline and after the 8-week intervention
|
Miary wyników drugorzędnych
Miara wyniku |
Opis środka |
Ramy czasowe |
|---|---|---|
|
Change in Manual Ability in Daily Activities
Ramy czasowe: Baseline and after the 8-week intervention
|
Manual ability in daily activities will be assessed using the ABILHAND-Kids questionnaire.
The questionnaire evaluates the child's perceived difficulty in performing everyday bimanual activities.
Higher scores indicate better manual ability.
|
Baseline and after the 8-week intervention
|
|
Change in Hand Grip Strength
Ramy czasowe: Baseline and after the 8-week intervention
|
Hand grip strength of the affected hand will be assessed using a Jamar hand dynamometer.
Grip strength will be recorded in kilograms.
Higher values indicate greater hand grip strength.
|
Baseline and after the 8-week intervention
|
Współpracownicy i badacze
Sponsor
Współpracownicy
Śledczy
- Dyrektor Studium: İrem Çetinkaya, PhD, Marmara University
Daty zapisu na studia
Główne daty studiów
Rozpoczęcie studiów (Szacowany)
Zakończenie podstawowe (Szacowany)
Ukończenie studiów (Szacowany)
Daty rejestracji na studia
Pierwszy przesłany
Pierwszy przesłany, który spełnia kryteria kontroli jakości
Pierwszy wysłany (Rzeczywisty)
Aktualizacje rekordów badań
Ostatnia wysłana aktualizacja (Rzeczywisty)
Ostatnia przesłana aktualizacja, która spełniała kryteria kontroli jakości
Ostatnia weryfikacja
Więcej informacji
Terminy związane z tym badaniem
Słowa kluczowe
Dodatkowe istotne warunki MeSH
Inne numery identyfikacyjne badania
- karanki9
Plan dla danych uczestnika indywidualnego (IPD)
Planujesz udostępniać dane poszczególnych uczestników (IPD)?
Informacje o lekach i urządzeniach, dokumenty badawcze
Bada produkt leczniczy regulowany przez amerykańską FDA
Bada produkt urządzenia regulowany przez amerykańską FDA
Te informacje zostały pobrane bezpośrednio ze strony internetowej clinicaltrials.gov bez żadnych zmian. Jeśli chcesz zmienić, usunąć lub zaktualizować dane swojego badania, skontaktuj się z register@clinicaltrials.gov. Gdy tylko zmiana zostanie wprowadzona na stronie clinicaltrials.gov, zostanie ona automatycznie zaktualizowana również na naszej stronie internetowej .