We Want to See if There is a Correlation Between Stress and the Microbiome for Pilots and Astronauts and if we Can Find a Way to Optimize This Balance for Pilots so That They Can Maximize Aerodynamic Decision Making on the Flight Deck.

September 14, 2026 updated by: Alison Adams, University of Nebraska

Role of the Microbiome in Regulating Stress Response in Pilots, a Means of Determining Optimal Diets for Fighter Pilots and Airline Pilots

We are going to test the bacteria growing in your intestine to see if they can influence your ability to manage stress while flying an airplane.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

20

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

Healthy licensed instrument rated pilots.

Description

Inclusion Criteria:

  • Healthy instrument rated pilot

Exclusion Criteria:

  • Mental illness, chronic inflammatory disease, gastrointestinal disease.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Pilots
18-25 year old aviation students
Behavioral: Flight simulator
Use of flight simulator
Other Names:
  • Aeronautical Simulation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Microbial activity relationship to stress tolerance.
Time Frame: 30 minute simulation
Correlation of microbiome with stress tolerance in flight simulation.
30 minute simulation
Microbial metabolic pathways
Time Frame: 30 minute simulation.
We will evaluate the correlation between microbial strains and their metabolic activity with the ability to handle stressful situations in a flight simulator.
30 minute simulation.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Nebraska

Investigators

  • Principal Investigator: Alison Adams, MS, UNO

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

September 1, 2026

Primary Completion (Estimated)

October 30, 2026

Study Completion (Estimated)

November 1, 2026

Study Registration Dates

First Submitted

September 14, 2026

First Submitted That Met QC Criteria

September 14, 2026

First Posted (Actual)

September 18, 2026

Study Record Updates

Last Update Posted (Actual)

September 18, 2026

Last Update Submitted That Met QC Criteria

September 14, 2026

Last Verified

September 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • 0398-26-FB

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Subscribe