The Impact of Generative Artificial Intelligence Dependency on Cognitive Function of University Students: A Cross-Sectional Study.

November 6, 2026 updated by: Sara Abdullah Mohamed, Faculty of Physical Therapy, MUST University

This observational cross-sectional study aims to investigate the relationship between dependence on generative artificial intelligence (AI) tools and cognitive functioning among university students.

Study Overview

Status

Not yet recruiting

Detailed Description

The increasing integration of generative artificial intelligence (GenAI) into higher education has transformed how university students access information, understand academic concepts, and complete learning activities. Although these technologies offer educational benefits, excessive dependence on AI-generated responses may be associated with cognitive offloading and reduced engagement in independent thinking and problem-solving.

This study aims to examine the association between generative AI dependency and cognitive functioning among university students, with particular attention to cognitive domains such as attention, memory, and executive functioning.

An observational cross-sectional design will be employed. Eligible university students aged 18-25 years will be invited to participate voluntarily through online announcements and electronic survey links. Informed consent will be obtained before data collection.

Participants will complete a structured online questionnaire collecting demographic and academic information, patterns of generative AI use, dependency-related responses, and measures of cognitive functioning.

The collected data will be analyzed using descriptive statistics, correlation analysis, and regression analysis to explore the relationship between AI dependency and cognitive functioning.

As this is a cross-sectional observational study, the results will identify possible associations but will not establish a causal relationship between generative AI dependency and changes in cognitive functioning.

The findings may contribute to understanding the educational implications of generative AI dependency and inform future research and teaching strategies promoting responsible AI use.

Study Type

Observational

Enrollment (Estimated)

107

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

      • Giza, Egypt
        • Faculty of Physical Therapy, Misr University for Science and Technology (MUST)
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 25 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

The study population will include university students aged 18-25 years who use generative artificial intelligence (AI) tools for academic or daily activities. Eligible participants will be recruited from selected universities through electronic announcements, institutional emails, and online survey links. Participation will be voluntary, and informed consent will be obtained before completing the questionnaires assessing generative AI dependency and cognitive functioning.

Description

Inclusion Criteria:

  • Enrolled undergraduate or graduate university students.
  • Active users of digital devices and generative AI tools for academic or daily tasks.
  • Ages between 18 and 25 years.
  • Provided informed consent to participate in the study.

Exclusion Criteria:

  • Diagnosed neurological or psychiatric disorders known to affect cognitive function.
  • History of severe traumatic brain injury.
  • Concurrent use of central nervous system-active medications that significantly alter cognitive performance.
  • Incomplete questionnaire submissions.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: OTHER
  • Time Perspectives: CROSS_SECTIONAL

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
University Students

This cohort will include university students aged 18-25 years who use generative artificial intelligence (AI) tools. Participants will complete self-administered questionnaires assessing their level of generative AI dependency and cognitive functioning. Data will be collected at a single point in time to examine the association between these variables. No intervention will be administered.

No Intervention: Observational Cohort

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Generative AI Dependency
Time Frame: At enrollment (single assessment)

Measured via a validated Generative AI Dependency Scale or Questionnaire.

At enrollment (single assessment)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Cognitive Function
Time Frame: At enrollment (single assessment)

Assessed using standardized self-reported or validated neuropsychological instruments focusing on specific domains such as attention, memory, and executive function.

At enrollment (single assessment)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Sara Abdullah mohamed, PhD, Lecturer, MUST University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

November 15, 2026

Primary Completion (Estimated)

December 15, 2026

Study Completion (Estimated)

December 15, 2026

Study Registration Dates

First Submitted

November 6, 2026

First Submitted That Met QC Criteria

November 6, 2026

First Posted (Actual)

November 12, 2026

Study Record Updates

Last Update Posted (Actual)

November 12, 2026

Last Update Submitted That Met QC Criteria

November 6, 2026

Last Verified

November 1, 2026

More Information

Terms related to this study

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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