Search clinical trials for: Dose decrease

Total 7779 results

The University of Texas Health Science Center at...

Completed

Safety and Efficacy Study of TH-302 CNS Penetration in Recurrent High Grade Astrocytoma Following Bevacizumab

HIGH GRADE GLIOMA

United States
University of Pennsylvania

Terminated

PGD2 Formation in Vascular Injury (PGD2)

Coronary Artery Disease | Acute Coronary Syndrome | Stable Angina
Emergo Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Norketotifen in Healthy Subjects

Healthy Subjects

United States
Federal University of Minas Gerais
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Completed

Preoperative Bath in Patients Submitted to Hip Arthroplasty

Surgical Wound Infection

Brazil
Merck Sharp & Dohme LLC

Completed

Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843)

Type 2 Diabetes Mellitus
Celgene
Celgene Corporation

Completed

Combination Study of Pomalidomide, Marizomib, and Low-Dose Dexamethasone in Relapsed and Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Multiple Myeloma in Relapse

United States, Australia
USWM, LLC (dba US WorldMeds)

Completed

Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction

Substance Withdrawal Syndrome | Opiate Dependence | Opiate Addiction

United States
Galderma R&D

Completed

Efficacy and Safety Study of GK530G Versus CD0271 0.1% Gel and CD1579 2.5% Gel in the Treatment of Acne Vulgaris.

Acne Vulgaris

Japan
Chong Kun Dang Pharmaceutical

Completed

Study to Compare the Safety and Pharmacokinetics of CKD-330 8/5mg With Coadministration of the Two Separate Drugs

Hypertension

Korea, Republic of
University Hospital Muenster
Hannover Medical School; Deutsche Kinderkrebsstiftung; Gesellschaft fur Padiatrische...

Unknown

Prospective Trial for the Diagnosis and Treatment of Intracranial Germ Cell Tumors (SIOPCNSGCTII)

Intracranial Germ Cell Tumors

Germany
Max-Planck-Institute of Psychiatry

Completed

Venlafaxine Augmentation in Treatment Resistant Depression

Depression

Germany
Boehringer Ingelheim

Completed

Bioavailability of Lacidipine and Telmisartan Fixed Dose Combination Tablets Relative to Separate Tablets in Healthy Subjects

Healthy
AstraZeneca

Completed

Assessment of Low-dose ASA Discontinuation Risk Associated With Concomitant PPI Use During the First Year of ASA Therapy

Cardiovascular Prevention

Spain
Northwestern University

Withdrawn

The Effect of Ketamine in the Prevention of Hypoventilation in Patients Undergoing Deep Sedation Using Propofol and Fentanyl

Hypercarbia

United States
Integrative Health Technologies, Inc.

Unknown

Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular Health (AdBiotech)

Hyperlipidemia | Hypercholesteremia | Cholesterol

United States
University of Rochester
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Conditioning, the Placebo Effect, and Psoriasis

Psoriasis

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of 60 mg Nifedipine ER Tablets Under Non-fasting Conditions

Healthy

United States
University of Aarhus
Velux Fonden

Completed

The Effect of Amlodipine and Lisinopril on Retinal Autoregulation in Type 1 Diabetes

Eye Diseases | Diabetes Complications | Diabetic Retinopathy | Type 1 Diabetes

Denmark
Vancouver General Hospital
Heart and Stroke Foundation of Canada; Vancouver Coastal Health Research Institute

Completed

Aminophylline in Bradyasystolic Cardiac Arrest

Cardiac Arrest

Canada
Khon Kaen University

Completed

Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain

a Single-Dose of Etoricoxib | Post-Operative Morphine Consumption | Total Pain Relief Over 8 Hr(TOPAR8) | Post Transabdominal Hysterectomy

Thailand
GlaxoSmithKline

Completed

Immunogenicity and Safety of a Commercially Available Vaccine Co-administered With GSK HPV Vaccine (580299)

Infections, Papillomavirus | Papillomavirus Vaccines

Belgium
Massachusetts General Hospital

Completed

Cast Immobilization for Non-Displaced Scaphoid Fractures

Non-displaced Scaphoid Fractures

United States
Activaero GmbH

Completed

AKITA Inhaled Steroid Suspension for Inhalation (AICS) in Subjects With Asthma

Asthma

Poland, Ukraine, Germany
Federal Research Institute of Pediatric Hematology...

Unknown

Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008 (ALL-MB 2008)

Childhood Acute Lymphoblastic Leukemia

Russian Federation, Belarus, Uzbekistan
M.D. Anderson Cancer Center
Eisai Inc.

Completed

Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI)

Sarcoma | Nausea | Vomiting

United States
Mayo Clinic

Recruiting

Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial (BEAR)

Ewing Sarcoma | Round Cell Sarcoma With EWSR1-non-ETS Fusion

United States
University Hospital, Basel, Switzerland

Completed

Intraoperative Ultrasound Guided Compared to Stereotactic Navigated Ventriculoperitoneal Shunt Placement (NaVPS)

Hydrocephalus | Ventriculoperitoneal Shunt (VPS)

Switzerland
Greg Durm, MD
AstraZeneca; Indiana University School of Medicine

Terminated

Chemoradiation Plus Durvalumab Followed by Surgery Followed by Adjuvant Durvalumab in Patients With Surgically Resectable Stage III (N2) Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer | Stage III Non-small-cell Lung Cancer

United States
Michael Vogelbaum, MD, PhD
Infuseon Therapeutics, Inc.

Withdrawn

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Glioma
Tehran University of Medical Sciences

Unknown

a Population Based Study on Metabolic Syndrome Complications, and Mortality (MetSCoM)

Metabolic Syndrome X

Iran, Islamic Republic of
MEDA Pharma GmbH & Co. KG

Completed

Dymista Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
St. Jude Children's Research Hospital
Novartis Pharmaceuticals; Spectrum Pharmaceuticals, Inc

Terminated

Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma

Acute Lymphoblastic Leukemia | Leukemia, B-Cell | Leukemia, T-Cell | Lymphoma, Non-Hodgkin's

United States
Research Insight LLC

Completed

A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1%

Cataract

United States
National Taiwan University Hospital

Completed

Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant Patients

Drug Interaction Potentiation

Taiwan
University of California, San Francisco
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of microRNAs in T Cell-Driven Inflammation in Asthma (RITA)

Asthma

United States
Shalvata Mental Health Center

Completed

A Study on the Effect of Methylphenidate on Creativity of Healthy Adults

MPH Influence on Creativity
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); United States Department of Defense

Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8

United States
University of Colorado, Denver

Terminated

Comparing Acular LS and Pred Forte in Reducing Post-selective Laser Trabeculoplasty Anterior Chamber Flare and Cells

Open Angle Glaucoma

United States
National Cancer Institute (NCI)

Completed

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland... and other conditions

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Istituto Di Ricerche Farmacologiche Mario Negri

Active, not recruiting

Screening and Multiple Intervention on Lung Epidemics (SMILE)

Smoking Cessation | Inflammation | Physical Activity | Lung Cancer | Diet Modification

Italy
University Hospital Freiburg
Roche Pharma AG; Genzyme, a Sanofi Company; Astellas Pharma GmbH

Completed

Phase IV Study to Evaluate Calcineurin Inhibitor Reduced, Steroid Free Immunosuppression After Renal Transplantation (Harmony)

Disorder Related to Renal Transplantation

Germany
Alza Corporation, DE, USA

Completed

Long-term Safety and Effectiveness of OROS Methylphenidate HCl in Children With Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder
Ronald Paquette

Active, not recruiting

Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil (OmitMMF)

Hematologic Neoplasms

United States
Fundació Institut de Recerca de l'Hospital de la...
Sociedad Española de Neumología y Cirugía Torácica; Universitat Autonoma de... and other collaborators

Completed

Detection and Use of Nasal Nitrous Oxide and the Electronic Nose (EPONA)

Allergic Rhinitis | Nasal Polyps | Non-Allergic Rhinitis

Spain
Herning Hospital

Completed

The Effect of Caffeine in Elderly Citizens

Healthy Elderly Citizens

Denmark
Tanabe Pharma Corporation

Completed

Efficacy and Safety Study of MP-435 in Combination With Methotrexate (MTX) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
King's College London
Shire

Completed

Brain Connectivity in Attention Deficit Hyperactivity Disorder (ADHD) (BCADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

United Kingdom
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Recruiting

CARS: Cannabis and Alcohol Reduction Study (CARS)

Substance Use | Substance Use Disorders | Cannabis Use | Alcohol Use, Unspecified

United States
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Terminated

Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria

Malaria

Korea, Republic of
Children's Hospital Medical Center, Cincinnati
Every Child Succeeds; de Cavel Family SIDS Foundation

Completed

Comparing Children's Book to Brochures for Safe Sleep Education in a Home Visiting Program

Sudden Infant Death Syndrome (SIDS)

United States

Search clinical trials for: Dose decrease

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