The Effect of Caffeine in Elderly Citizens

July 3, 2006 updated by: Herning Hospital

The Effect of Caffeine as Endurance Enhancing Drug in the Elderly

The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years. The main hypothesis was that 6 mg/kg caffeine would improve cycling endurance at 65% of expected maximal heart rate.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Caffeine ingestion increases the endurance of young people exercising at 60%-85% of their maximal oxygen uptake, and it also seems to improve endurance as measured by repeated sub-maximal isometric contraction and decreases the rate of perceived exertion during exercise. Although caffeine increases endurance in young people, an increase in endurance may be of greater interest in the elderly as the population of older adults with a physically active lifestyle is growing rapidly or for increasing endurance fitness through an exercise or rehabilitation program. Therefore the main hypothesis was that caffeine would improve cycling endurance at 65% of expected maximal heart rate, and the secondary hypotheses were that caffeine would improve postural stability, reaction and movement times, isometric arm flexion endurance, and walking speed, and would reduce the rate of perceived exertion after 5 minutes of cycling in healthy elderly citizens.

Study Type

Interventional

Enrollment

30

Phase

  • Phase 4

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Denmark
    • Ringkjoebing
      • Herning, Ringkjoebing, Denmark, 7400
        • Surgical Research Department

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

70 years and older (Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Healthy elderly individuals aged over 70 years

Exclusion Criteria:

  • Dementia or invalidating psychiatric disease
  • General debility, angina, or other diseases that would render participation in the test program impossible
  • Treatment with beta receptor blocking drugs, calcium-channel blocking drugs, digitalis, or nitroglycerine
  • Acute disease and injury
  • Diabetes
  • Conditions that would contraindicate caffeine ingestion or participation in the test program
  • Treatment with medication that interacts with caffeine
  • Ingestion of caffeine containing drinks and foods 48 hours before each session

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Double

What is the study measuring?

Primary Outcome Measures

Outcome Measure
endurance measured on an ergometer bicycle

Secondary Outcome Measures

Outcome Measure
fatigue
postural stability
reactiontime
isometric endurance (armflexion)
walking speed

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Herning Hospital

Investigators

  • Principal Investigator: Charlotte B Norager, M.D, Surgical Research Department, Herning Hospital, DK-7400 Herning

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

July 1, 2002

Study Completion

March 1, 2006

Study Registration Dates

First Submitted

June 30, 2005

First Submitted That Met QC Criteria

June 30, 2005

First Posted (Estimate)

July 7, 2005

Study Record Updates

Last Update Posted (Estimate)

July 7, 2006

Last Update Submitted That Met QC Criteria

July 3, 2006

Last Verified

July 1, 2002

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2612-1987

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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