Search clinical trials for: Dose decrease

Total 7779 results

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Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Amlodipine/Atorvastatin Combination to Reduce the Health Risk of High Blood Pressure and High Cholesterol Levels (GEMINI-AALA)

Hypertension | Hyperlipidemia

Brazil, Turkey, Taiwan, Argentina, India, Philippines, Singapore, Thailand, Australia, Chile, South Africa, Jordan, Korea, Republic of, Lebanon, United Arab Emirates, Malaysia, Peru, Israel, Indonesia, Guatemala, Hong Kong, Kuwait, ... and more
Adebayo Joshua Adeniyi

Completed

Low Dose Magnesium Sulphate Versus Standard Pritchard Regimen In Management Of Severe Preeclampsia/Eclampsia

Preeclampsia/Eclampsia

Nigeria
Leonardo Clavijo
Amgen

Unknown

Effect of Evolocumab in Functional Status and LDL Oxidation of Patients With Peripheral Arterial Disease (Evol-PAD)

Peripheral Arterial Disease

United States
Keele University

Completed

Colchicine Or Naproxen Treatment for ACute gouT (CONTACT)

Gout

United Kingdom
Emory University
Boston Medical Center; Rush University; University of Denver

Completed

Linagliptin Inpatient Trial

Type 2 Diabetes

United States
Ferrer Internacional S.A.

Unknown

Pharmacodynamic Equivalence of Ramipril 10 mg and Atorvastatin 40 mg Administered as a Cardiovascular (CV) Polypill Acetylsalicylic Acid-Atorvastatin-Ramipril (AAR) as Compared to Monotherapy

Hypertension

United States
Genuine Research Center, Egypt
Pharmacare PLC, Palestine

Completed

A Bioequivalence Study of Amlodipine / Valsartan From Amlodipine/Valsartan 10/160 Tablets (Pharmacare, Palestine) and Exforge Tablets (Novartis Pharma, USA)

Healthy

Egypt
AstraZeneca

Completed

Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil

Type 2 Diabetes Mellitus

Brazil
PETHEMA Foundation

Completed

MINIALO-VELCADE2005: A Study of Bortezomib (Velcade) Treated Multiple Myeloma Patients Pre and Post Allogeneic Haematopoietic Progenitor Cell Transplant With no Myeloablative Conditioning (MINIALO-VELCAD)

Multiple Myeloma

Spain
Boehringer Ingelheim

Completed

Relative Bioavailability of Telmisartan/Amlodipine Fixed-dose Combination Compared to Its Mono-components in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Telmisartan/Amlodipine (80/5) vs. Telmisartan/Amlodipine (40/5) vs. Amlodipine 10 or 5 in Resistant Hypertension

Hypertension

Belgium, Canada, Denmark, Finland, France, Korea, Republic of, Netherlands, Norway, Philippines, South Africa, Sweden, Taiwan
Yoo-Sook Joung
Korea Otsuka International Asia Arab

Unknown

Study to Evaluate the Efficacy and Safety of Aripiprazole

Autism

Korea, Republic of, Philippines, Thailand
Boehringer Ingelheim

Completed

Telmisartan/Amlodipine (80/10) vs. Telmisartan/Amlodipine (40/10) vs. amlodipine10 in Resistant Hypertension

Hypertension

Australia, Austria, Bulgaria, Czech Republic, Ireland, Italy, New Zealand, Russian Federation, Slovakia, Spain, Switzerland, Turkey, Ukraine, United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Crossover Study to Assess the Bioequivalence of Hydrocodone Bitartrate Extended-Release Tablet

Pain

United States
Massachusetts General Hospital
Bristol-Myers Squibb

Completed

The Combination of Aripiprazole and Antidepressants in Psychotic Major Depression (Abilify)

Psychotic Depression

United States
USDA, Western Human Nutrition Research Center
HarvestPlus

Completed

Vitamin A Absorption From Cassava in Women (FL-80)

Vitamin A Deficiency

United States
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France; Baxter Healthcare Corporation; Amgen

Completed

High-dose Chemotherapy With Autologous Stem Cell Transplantation in Poor Prognosis Germ-cell Tumors: TAXIF II

Testicular Neoplasms

France
Istituto Clinico Humanitas

Completed

A Phase II Study of IGEV +/- Bortezomib Before Hign Dose Consolidation in Relapsed/Refractory Hodgkin's Lymphoma

Hodgkin Disease

Italy
Actavis Inc.

Completed

A Relative Bioavailability Study of Gabapentin 400 mg Capsules Under Non-fasting Conditions

Healthy

United States
SpringWorks Therapeutics, Inc., a healthcare company...

Completed

Evaluate the Effects of Famotidine or Rabeprazole on the PK of Nirogacestat

Healthy

United States
Line Kessel

Completed

Study for Optimizing Anti-inflammatory Prophylaxis (SOAP)

Irvine-Gass Syndrome | Postoperative Cystoid Macular Edema

Denmark
Novartis Pharmaceuticals

Completed

Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients

Renal Function

Denmark, Norway, Sweden
University of Oklahoma

Completed

Caffeine and Cerebrovascular Reactivity

Caffeine

United States
Anna Cruceta

Withdrawn

Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes. (DIAB-01)

Type 1 Diabetes Mellitus

Spain
Pharmaxis

Completed

Inhaled TPI-1020 Versus Inhaled Budesonide in Smokers With Mild Reversible Asthma

Asthma

Canada
University Hospital, Toulouse

Not yet recruiting

Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder (BorderKET)

Borderline Personality Disorder (BPD) | Infusion of Ketamine in Severe Borderline Personality Disorder

France
The Third People's Hospital of Bengbu

Recruiting

Norepinephrine on Maternal Hypotension After Combined Lumbar and Epidural Anaesthesia

Maternal Hypotension

China
Wayne State University
The Gerber Foundation

Terminated

Early Versus Late Caffeine for ELBW Newborns

Bronchopulmonary Dysplasia | Apnea of Prematurity

United States
Provectus Biopharmaceuticals, Inc.

Terminated

PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma

Cutaneous Melanoma

United States, Mexico, France, Germany, Italy
Weill Medical College of Cornell University

Completed

Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers

Chronic Obstructive Pulmonary Disease (COPD)

United States
Novo Nordisk A/S

Completed

Comparison of the Effect of NN5401 With the Effect of NN1250 and Insulin Aspart in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Germany
Mayo Clinic
National Center for Research Resources (NCRR); Rose Pharma A/S

Completed

Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients

Irritable Bowel Syndrome Constipation Predominant

United States
NeuroRx, Inc.
Massachusetts General Hospital; Target Health Inc.

Completed

Sequential Therapy for the Treatment of Severe Bipolar Depression. (STABIL-B)

Suicidal Ideation | Suicide, Attempted | Bipolar Depression | Suicidal Ideas

United States
University of Texas Southwestern Medical Center

Completed

Pain Relief Effects on Length of Labor

Labor Pain

United States
Heidelberg University

Unknown

Prospective Trial on Immunochemotherapy Plus Autologous Stem Cell Transplantation (SCT) and Allogenic SCT in Primary Mantle-Cell-Lymphoma (HD-MCL2003)

Mantle-Cell Lymphoma

Germany
Memorial Sloan Kettering Cancer Center

Completed

Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia | Advanced Myelodysplastic Syndromes

United States
GlaxoSmithKline

Completed

A Phase III Parallel Group Study, Comparing the Efficacy, Safety and Tolerability of the Fixed Dose Combination (FDC) of Fluticasone Furoate+Umeclidinium Bromide+Vilanterol (FF/UMEC/VI) With the FDC of FF/VI in Subjects With Inadequately Controlled Asthma

Asthma

Australia, United States, Argentina, Canada, Germany, Japan, Korea, Republic of, Romania, Russian Federation, Spain, South Africa, Netherlands, Poland, Italy, United Kingdom
Tanta University

Unknown

Clinical Evaluation of New Treatment Strategy of Mucous Membrane Pemphigoid Using Large Dose of Prednisolone Plus Intra-lesional of Triamcinolone Acetonide Followed by Combination of Mycophenolate Mofetil, Dapsone and Low Dose Prednisolone

Benign Mucous Membrane Pemphigoid

Egypt
European Mantle Cell Lymphoma Network
Lymphoma Study Association; German Low Grade Lymphoma Study Group

Unknown

Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL

Lymphoma, Mantle-Cell

France, Germany, Poland
Hallym University Medical Center
Sanofi; Asan Medical Center

Completed

Docetaxel, Oxaliplatin and S-1 (DOS) for Advanced Gastric Cancer

Stomach Neoplasms

Korea, Republic of
Peking Union Medical College Hospital

Not yet recruiting

Efficacy and Safety of Adalimumab Plus Medium Dose Oral Glucocorticosteroid for Refractory Behçet's Uveitis

Uveitis
Region Skane

Completed

Effects of Extra Corporeal Circuit Prime on Electrolytes Balance and Clinical Outcome Following Cardiac Surgery (Prime)

Cardiac Surgery

Sweden
Novo Nordisk A/S

Completed

A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus. (DUAL™ I Japan)

Diabetes Mellitus, Type 2 | Diabetes

Japan
Massachusetts General Hospital

Completed

Proton Magnetic Spectroscopy in Children and Adolescents With ADHD Before and After Treatment With OROS Methylphenidate

ADHD

United States
Massachusetts General Hospital
The Hospital for Sick Children; National Institute of Diabetes and Digestive...

Completed

Effects of Anorexia Nervosa on Bone Mass in Adolescents

Anorexia Nervosa

United States
University Hospital, Grenoble
Ligue contre le cancer, France; Fondation de France

Terminated

Ritalin: Antiasthenic Effect of Methylphenidate (Ritalin) in Palliative Care in Cancer Patients (Ritaline)

Neoplasms | Asthenia

France
Qiu-ping Lin

Not yet recruiting

Effect of Acupuncture Plus Governor Vessel Moxibustion Combined With Letrozole on Live Birth in Anovulatory Infertile Women With Spleen-kidney Yang Deficiency PCOS (PCOS)

PCOS | Infertility, Female
Washington University School of Medicine

Withdrawn

The Perinatal Synergistic Multi-component Intervention to alLeviate dEpressive Symptoms. A Case Series (SMILES)

Postpartum Depression

United States
David Grant U.S. Air Force Medical Center

Withdrawn

Synthetic and Natural Caffeine on Hemodynamic Parameters in Young, Healthy Volunteers

Cardiovascular Injury

United States
Zhujiang Hospital

Completed

Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock (HYVCTTSSS)

Sepsis

China

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