Search clinical trials for: Dose decrease

Total 7779 results

University of British Columbia
Post Graduate Institute of Medical Education and Research, Chandigarh

Unknown

Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma

Asthma in Children | Asthma Acute
Centro Nacional de Investigaciones Oncologicas...
Apices Soluciones S.L.; Hospital Universitario de Fuenlabrada; Grupo Hospital...

Completed

Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic

Metastatic Disease | Adenocarcinoma of Rectum | Adenocarcinoma of Colon

Spain
University of Chicago

Withdrawn

Turning Dexmedetomidine Into a Powerful Anesthetic That Can be Rapidly and Completely Reversed

Emergence From Anesthesia

United States
University of California, Davis
Sanofi

Terminated

Cabazitaxel and Prednisone in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

Hormone-Resistant Prostate Cancer | Stage IV Prostate Adenocarcinoma

United States
University of Edinburgh
NHS Lothian; Chief Scientist Office of the Scottish Government

Completed

Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol Poisoning Study (SNAP) (SNAP)

Overdose

United Kingdom
Centers for Disease Control and Prevention

Terminated

Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Vivax in Pregnancy in Brazil (PAACT-PV) (PAACT-PV)

Plasmodium Vivax Malaria

Brazil
Huilian Zhu

Not yet recruiting

Effects of Milk Probiotics Intervention on Blood Glucose Control Middle-aged and Elderly People With Pre-diabetes

Pre-biabetes
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC; Seagen Inc.

Active, not recruiting

PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma

Hodgkin Lymphoma

United States
Northwell Health
AstraZeneca; Jacobi Medical Center; Nassau University Medical Center

Completed

Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.

Asthma

United States
Duke University
IWK Health Centre

Completed

Prevention of Intraoperative Nausea and Vomiting During Cesarean Section

Cesarean Delivery

United States
Region Skane

Completed

General vs. Intrathecal Anesthesia for Total Knee Arthroplasty

Arthritis

Sweden
University of Southern Denmark
Odense University Hospital

Terminated

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Cytochrome P450 Phenotype and Genotype Metrics

Denmark
Hoffmann-La Roche
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants (POSTERITY)

Lupus Nephritis

United States, Mexico, Canada, Spain, United Kingdom, France, Italy, Peru, Brazil, Poland, South Africa, Russia
Dr. Nazanin Alavi
Online PsychoTherapy Clinic

Completed

Efficacy of Online CBT for GAD Compared to Pharmaceutical Interventions

Generalized Anxiety Disorder

Canada
Eli Lilly and Company

Completed

A Study of LY3023414 in Participants With Advanced Cancer

Non-Hodgkin's Lymphoma | Metastatic Cancer | Malignant Mesothelioma | Metastatic Breast Cancer | Non-small Cell Lung Cancer | Advanced Cancer

United States, Puerto Rico, Italy
Consorzio Futuro in Ricerca

Completed

Comparative Study on Usability of Inhaler Devices in Adults With Asthma or COPD (PMC-101-APT)

Asthma | COPD

Italy
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS) (MARS)

Asthma

United States
Scott and White Hospital & Clinic
Merck Sharp & Dohme LLC

Completed

Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery Patients

Postoperative Nausea and Vomiting

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Yttrium-90 Ibritumomab Tiuxetan Plus High-Dose BEAM Followed By ASCT For Relapsed B-Cell Non-Hodgkin Lymphoma

Lymphoma

United States
M.D. Anderson Cancer Center
Bayer

Terminated

Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma

Lymphoma

United States
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

Drug-drug Interaction Study of XZP-3621 Tablet

Healthy Subjects

China
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Rituximab and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Non-Hodgkin's Lymphoma

Lymphoma

United States
King's College Hospital NHS Trust
King's College London; Fight for Sight (Funder)

Recruiting

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER). (TIGER)

Eye Diseases | Macular Degeneration, Wet | Sub-Macular Hemorrhage

United Kingdom, Germany, Switzerland, Ireland, Poland
AstraZeneca

Completed

Symbicort Onset of Action 2

Asthma
University of Missouri-Columbia
Kansas City Veteran Affairs Medical Center

Completed

Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic Dysfunction

Diastolic Dysfunction

United States
National Cancer Institute (NCI)

Completed

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced Solid Tumors

Adult Solid Neoplasm

United States
Parth Patel
Children's of Alabama

Active, not recruiting

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

Medulloblastoma | Central Nervous System Embryonal Tumors

United States, New Zealand, Canada
Cedars-Sinai Medical Center
United States Department of Defense; University of Florida

Active, not recruiting

Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD (WARRIOR)

Coronary Artery Disease

United States, Puerto Rico
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Active, not recruiting

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) (TransIT)

Severe Aplastic Anemia

United States, Canada
Incyte Corporation

Completed

A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

Graft-versus-host Disease (GVHD)

Belgium, Italy, Spain, Saudi Arabia, Turkey, United Kingdom, Germany, Greece, Canada, Austria, France, Israel, Netherlands, Sweden, Switzerland, Korea, Republic of, Bulgaria, Japan, Norway, Czechia, Russian Federation, Jordan, Hungary, Ind... and more
University of Cape Town

Completed

Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBM (LASER-TBM)

HIV-1-infection | Tuberculosis Meningitis

South Africa
Memorial Sloan Kettering Cancer Center
Boehringer Ingelheim; National Comprehensive Cancer Network

Completed

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Head and Neck Cancer | Squamous Cell Cancer

United States
National University of Singapore
The University of Queensland; European Clinical Research Alliance for Infectious...

Recruiting

Optimising TREATment for Severe Gram-Negative Bacterial Infections (TREAT-GNB)

Bloodstream Infection | Multidrug Resistance | Hospital Acquired Bacterial Pneumonia | Carbapenem Resistant Bacterial Infection | Ventilator Associated Bacterial Pneumonia

South Africa, Spain, Singapore, Malaysia, Turkey, Qatar, Lebanon, Australia, Thailand, China, Saudi Arabia, United Arab Emirates
TASK Applied Science
Innovative Medicines Initiative

Recruiting

A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination with Ethionamide (ENABLE)

Tuberculosis

South Africa
Felix Gutierrez
Hospital Clinic of Barcelona; Hospital General Universitario Elche; Germans Trias... and other collaborators

Recruiting

IMPACt of an Enhanced Screening Program on the Detection of Non-AIDS NEOplasms in HIV Patients (IMPACNEO)

Cancer | HIV/AIDS

Spain
Kite, A Gilead Company

Completed

Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma (ZUMA-1)

Relapsed Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B Cell Lymphoma (DLBCL) | Transformed Follicular Lymphoma (TFL) | Primary Mediastinal B-cell Lymphoma (PMBCL) | High Grade B-cell Lymphoma (HGBCL)

United States, Netherlands, Canada, France, Germany, Israel
Xi'an International Medical Center Hospital

Completed

Efficacy and Safety of High-dose Vitamin C Combined With Chinese Medicine Against Coronavirus Pneumonia (COVID-19)

COVID-19

China
Alexandria University

Completed

The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study

Bacterial Keratitis | Fungal Keratitis | Mixed Bacterial and Fungal Keratitis | Microbial Keratitis

Egypt
University Children's Hospital Basel

Recruiting

Early Pulmonary Dysfunction in Childhood Cancer Patients (SWISS-Pearl)

Pulmonary Dysfunction

Switzerland
Zambon SpA

Completed

A Clinical Study to Evaluate Z7200 (Budesonide/Formoterol) Pharmacokinetics Profile in Healthy Volunteers

Asthma

United Kingdom
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Psoriasis

United States
National Cancer Institute (NCI)
Children's Cancer Group

Completed

506U78 in Treating Patients With Refractory Hematologic Cancer

Recurrent Childhood Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Lymphoblastic Lymphoma

United States
Medical University of Vienna

Completed

Mechanisms of Choroidal Blood Flow Changes During Dark/Light Transitions

Ocular Physiology | Regional Blood Flow

Austria
Indian Council of Medical Research
Christian Medical College, Vellore, India; Jawaharlal Institute of Postgraduate... and other collaborators

Not yet recruiting

Intensified Short Course Regimen for TBM in Adults (INSHORT)

Tuberculous Meningitis

India
University of Illinois at Chicago
UCB Pharma

Completed

IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA

Rheumatoid Arthritis

United States
Taizhou Hospital
First Affiliated Hospital of Zhejiang University; Taizhou First People's Hospital and other collaborators

Unknown

A Multi-center Study for Eradication of Refractory Helicobacter Pylori

Gastritis

China
Beth Israel Deaconess Medical Center

Recruiting

Gait Analysis in Neurological Disease

Parkinson's Disease | Parkinsonian Disorders | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Huntington Disease | Atypical Parkinson Disease | Gait, Frontal

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Active, not recruiting

Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Recurrent Prostate Carcinoma | Stage IV Prostate Cancer AJCC v7

United States
Fundacion SEIMC-GESIDA

Completed

Study to Evaluate the Efficacy and Safety of a Rilpivarine-based Antiretroviral Tratment Regimen in HIV- Infected Patients With Liver Metabolic Disease Who Maintain Udetectable HIV Viral Load (MAFALDA-R)

HIV Infections | Fatty Liver Disease

Spain
Latin American Cooperative Oncology Group
Merck Sharp & Dohme LLC

Active, not recruiting

Study of a Pembrolizumab-based Organ Preservation Strategy for Locally Advanced Larynx Cancers (SMART-KEY)

Squamous Cell Carcinoma of Larynx

Brazil

Search clinical trials for: Dose decrease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in France

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations