Search clinical trials for: Dose decrease

Total 7785 results

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N.N. Petrov National Medical Research Center of...

Completed

CT Screening For Lung Cancer in High Risk Patients: the Russian Study.

Lung Cancer

Russian Federation
McMaster University
McMaster Surgical Associates

Completed

Does Intense Regimented Surveillance Improve the Rates of Therapeutic Re-Intervention After Lung Cancer Surgery (Intense-CT)

Lung Neoplasms

Canada
Pfizer

Withdrawn

The Bioavailability of a Spray Dried Dispersion Solid Dose Formulation of PF-06260414 Relative to a Suspension Formulation

Healthy

United States
Merck Sharp & Dohme LLC

Completed

Polysomnography Study of MK-6096 in Participants With Primary Insomnia (MK-6096-011)

Primary Insomnia
Balgrist University Hospital

Completed

Three-Dimensional Hindfoot Alignment Measurements Based On Biplanar Radiographs: Prospective Clinical Feasibility Study

Congenital Medial Deviation

Switzerland
Oslo University Hospital
University of Oslo

Completed

Experiences With HDR-brachytherapy in Norway

Prostate Cancer

Norway
Yale University

Completed

Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing In Gammopathy Patients (SHIVERING)

Influenza | Gammopathy

United States
Stanford University
National Institutes of Health (NIH)

Completed

Enrichment & Purging of Stem Cells in Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

United States
National University Hospital, Singapore
Tan Tock Seng Hospital

Unknown

Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer

Rectal Cancers.

Singapore
Boehringer Ingelheim

Completed

Relative Bioavailability of 1 mg and 10 mg BI 1356 BS as Powder in the Bottle (PIB) to 1 mg and 10 mg BI 1356 BS as Tablets as Single Oral Administration in Healthy Male Volunteers Including the Influence of Food on the Bioavailability of 10 mg BI 1356 BS

Healthy
Amway (China) R&D Center

Recruiting

The Efficacy of Amway Uric Acid Lowering Product on Hyperuricemia

Hyperuricemia

China
Palatin Technologies, Inc

Terminated

Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects

Heart Failure With Preserved Ejection Fraction

United States
Swedish Orphan Biovitrum

Completed

A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy (DISSOLVE I)

Chronic Gout

United States
Hutchmed

Completed

A Study of HMPL-295S1 in Patients With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors

China
University of Miami

Completed

Optimal Protamine Dosing for Heparin Reversal Following Cardiopulmonary Bypass

Coagulation; Intravascular

United States
Assistance Publique - Hôpitaux de Paris
Janssen, LP

Completed

Desensitization in Kidney Allograft Using Daratumumab (DARDAR)

Kidney Transplant Rejection | Antibody-mediated Rejection | Allosensitization

France
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Multi-Dose Quadrivalent Influenza Vaccine

Influenza

Mexico
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai East Hospital; The Second Affiliated... and other collaborators

Completed

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase (CHABLIS-T)

Stroke

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Howard University; Prostate Cancer Clinical Trials Consortium

Completed

Effects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Therapy for Prostate Cancer

Prostate Cancer

United States
United Therapeutics
CVie Therapeutics Co. Ltd.

Withdrawn

Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China
Blokhin's Russian Cancer Research Center

Enrolling by invitation

Low-dose Immunotherapy in Metastatic and Locally Advanced Colorectal and Gastric MSI/dMMR Cancers (NIVO402025)

Gastric Cancer | Colorectal Cancer

Russia
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve Adults

Zika Virus

United States
Boehringer Ingelheim

Completed

Safety, Pharmacodynamics and Pharmacokinetics After Single Oral Administration of Dabigatran Etexilate Capsule in Healthy Subjects

Healthy
Asan Medical Center

Recruiting

Influenza Vaccination Strategy for Patients With Hematologic Malignancy ((HEM-FLU))

Hematologic Neoplasms | Influenza | Immunogenicity

South Korea
Monyan Pharmaceutical (Shanghai) Co., Ltd.

Recruiting

A Multicenter Clinical Trial on DH001 Tablets in the Prevention of Doxorubicin-induced Cardiotoxicity in Cancer Patients

Heart Failure | Cancer | Arrhythmia | Doxorubicin Induced Cardiomyopathy | Doxorubicin Adverse Reaction

China
TRB Chemedica International SA

Recruiting

Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease (BUSTON-02)

Dry Eye Disease

France, Austria
TRB Chemedica International SA

Recruiting

Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease (BUSTON-01)

Dry Eye Disease

France
Jonsson Comprehensive Cancer Center
Sarcoma Alliance for Research through Collaboration; Radiological Society of... and other collaborators

Recruiting

Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

Recurrent Adult Soft Tissue Sarcoma

United States
Jingjing Jiao

Completed

Fish Oil for Cognitive Function, Sleep Quality, and Bone Density

Sleep | Cognitive Decline | Bone Mineral Density

China
CyanVac LLC

Completed

Phase 1 Study of Intranasal PIV5 COVID-19 Vaccine Expressing SARS-CoV-2 Spike Protein in Healthy Adults and Adolescents (CVXGA1-001)

Covid19

United States
Chong Kun Dang Pharmaceutical

Completed

The Parallel Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of CKD-843 A

Alopecia

Korea, Republic of
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects in a Phase Ⅱ Clinical Trial

Corneal Epithelial Defect

China
Shengjing Hospital
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Breast Cancer Study of Stereotactic Body Radiation Therapy (SBRT) Combined Neoadjuvant Treatment

Breast Cancer

China
Tasly Pharmaceutical Group Co., Ltd

Completed

Study of Jitongning Tablet to Treat Spondyloarthritis

Spondyloarthritis

China
Yale University

Completed

Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop Therapy

Post-Prandial Hyperglycemia | Post-Prandial Hypoglycemia

United States
Pontificia Universidad Catolica de Chile
Millennium Institute on Immunology and Immunotherapy; Comisión Nacional de...

Completed

A Study to Assess Safety, Tolerability and Immunogenicity of the Live Attenuated hRSV Vaccine rBCG-N-hRSV (EVA-VRS01)

Respiratory Syncytial Virus Infections

Chile
Northern Illinois University
Mayo Clinic; Nova Southeastern University; University of Wisconsin, La Crosse

Completed

Effects of a Multi-Ingredient Pre-Workout Supplement on Energy Expenditure During Running

Healthy
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BI 653048 H3PO4 Oral Drinking Solution in Healthy Male Volunteers

Healthy
Jiangsu Simcere Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study of SSD8432 in Healthy Adult Subjects

Healthy Participants

China
Tongji Hospital

Recruiting

Oliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid Study

Postoperative Analgesia

China
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH); Department of Health and Human Services

Active, not recruiting

Trial to Evaluate the Safety and Immunogenicity of Priming Regimens of 426c.Mod.Core-C4b and Optional Boost Regimen With HIV Trimer BG505 SOSIP.GT1.1 gp140, Both Adjuvanted With 3M-052-AF + Alum in Healthy, Adult Participants Without HIV

HIV-1-infection

United States
Actelion

Completed

Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of ACT-128800 in Patients With Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis

United States, Australia, Austria, Belgium, Bulgaria, Canada, Czechia, Finland, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Romania, Russian Federation, Serbia, Spain, Sweden, Switzerland, Ukraine, United Kingdom
Oxurion

Terminated

A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema. (INTEGRAL)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

Latvia, Lithuania, United States, Hungary, Estonia
GlaxoSmithKline

Completed

Safety and Immunogenicity of the Zoster Vaccine GSK1437173A in Elderly Subjects

Herpes Zoster

Germany, Czechia, Sweden, Netherlands
Yuejin Yang
Peking Union Medical College Hospital; The First Hospital of Hebei Medical... and other collaborators

Unknown

Transplantation Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells With Intensive Atorvastatin in AMI Patients (TEAM-AMI)

Myocardial Infarction | Stem Cell Transplantation | Angioplasty, Transluminal, Percutaneous Coronary
Boehringer Ingelheim

Completed

Effect of BIBT 986 Followed by BIBT 986 Given as IV Infusion on Tissue Factor Triggered Coagulation in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Klimadynon® in Comparison to Conjugated Oestrogens in Women Suffering From Menopausal Complaints

Menopause
Johnson & Johnson Consumer Inc., McNeil Consumer...

Completed

Acetaminophen/Naproxen Sodium Dose Ranging Study

Pain

United States
Merck Sharp & Dohme LLC

Completed

Comparative Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED)

Anesthesia
Locus Biosciences
Parexel

Recruiting

A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial) (ELIMINATE)

Urinary Tract Infections

United States

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