Search clinical trials for: Dose decrease

Total 7787 results

Idorsia Pharmaceuticals Ltd.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)

Healthy

France
Lawson Health Research Institute

Unknown

MEV 90 of 0.5% Ropivacaine In Infraclavicular Blocks (MEV90ROPI)

Infraclavicular Brachial Plexus Block
Bnai Zion Medical Center

Completed

Cortisol Response to Low Dose Cosyntropin Stimulation Test in the Late Afternoon

Adrenal Insufficiency

Israel
Weill Medical College of Cornell University

Terminated

Efficacy of Quetiapine for Pediatric Delirium

Delirium

United States
Bristol-Myers Squibb

Completed

A Phase 3 Study in Combination With BMS-790052 and BMS-650032 in Japanese Hepatitis C Virus (HCV) Patients

Hepatitis C

Japan
Sun Yat-sen University

Completed

Tolerability and Pharmacokinetics of M2ES in the Treatment of Advanced Solid Tumor

Pharmacokinetics | Tolerability | Endostatin

China
Third Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Transarterial Chemoembolization | Atezolizumab Plus Bevacizumab
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cambridge University Hospitals NHS Foundation... and other collaborators

Recruiting

5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours (5G-RUBY)

Glioblastoma Multiforme (GBM) | Diffuse Hemispheric Glioma, H3 G34-Mutant | Glioblastoma Multiform (Grade IV Astrocytoma) | Malignant Primary Gliomas

United Kingdom
M.D. Anderson Cancer Center

Recruiting

A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors

Refractory Solid Tumors

United States
Case Comprehensive Cancer Center

Completed

Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

Glioma | Glioblastoma

United States
Aucta Pharmaceuticals, Inc

Terminated

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Tuberous Sclerosis | Angiofibroma of Face

United States, China
Ataturk University

Completed

The Effect of Caudal Block on Optic Nerve Sheath Diameter in Pediatric Patients

Postoperative Pain | Intracranial Hypertension

Turkey
GlaxoSmithKline

Completed

DUAC® Early Onset Efficacy Study in Japanese Subjects

Acne Vulgaris

Japan
University of North Carolina, Chapel Hill
National Center for Complementary and Integrative Health (NCCIH)

Completed

A Study of Sublingual Immunotherapy in Peanut-allergic Children (SLB)

Food Hypersensitivity

United States
Hawaii Pacific Health
Genentech, Inc.

Completed

Investigator Sponsored Trial of Polypoidal Choroidal Vasculopathy (PCV) Evaluation Assessing High-Dose Ranibizumab Prospectively (PEARL2) (PEARL2)

Polypoidal Choroidal Vasculopathy | PCV

United States
The Cleveland Clinic

Completed

Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation

Colonoscopy | Esophagogastroduodenoscopy

United States
Johns Hopkins University
Juvenile Diabetes Research Foundation

Completed

Ranibizumab for Edema of the Macula in Diabetes: Protocol 3 With High Dose - the READ 3 Study (READ 3)

Diabetic Macular Edema

United States
University Hospital Freiburg

Unknown

Treatment of Advanced Castration Resistant Prostate Carcinoma With Limited Bone Metastases (α-RT) (α-RT)

Prostate Carcinoma

Germany
Boehringer Ingelheim

Completed

A Trial on Efficacy and Safety of Full Dose Tenecteplase Combined With Unfractionated Heparin (UFH) or Enoxaparin in Acute Myocardial Infarction (AMI) in the Prehospital Setting (ASSENT 3 Plus)

Myocardial Infarction
Sanofi

Completed

Study of Live Attenuated ChimeriVax™-Japanese Encephalitis Vaccine

Japanese Encephalitis

Australia
Hopital A Michallon
Central Hospital, Nancy, France; University Hospital, Grenoble

Terminated

Plasma Ribavirin Assay During Combination Therapy for Chronic Hepatitis C

Chronic Hepatitis C

France
Shire
Takeda

Completed

FIRAZYR General Drug Use-Results Survey (Japan)

Hereditary Angioedema (HAE)

Japan
Burdur Mehmet Akif Ersoy University

Completed

AI-Supported and Traditional Tennis Training in Individuals With Intellectual Disabilities (TENN-ID)

Intellectual Disability

Turkey (Türkiye)
Church & Dwight Company, Inc.

Completed

A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold

Nasal Congestion

Poland
West Virginia University

Completed

Technology-Assisted Prescription Opioid Safety Education (T-POSE)

Opioid Use

United States
Atea Pharmaceuticals, Inc.

Completed

Drug-drug Interaction Study of Omeprazole and Bemnifosbuvir/Ruzasvir

Healthy Volunteer Study

United States
Memorial Sloan Kettering Cancer Center
AstraZeneca

Recruiting

A Study of Lung Cancer Screening in People With Unexplained Weight Loss

Lung Cancer Screening

United States
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Recruiting

Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (XT1061)

Chronic Hepatitis b

China
CHU de Quebec-Universite Laval

Recruiting

A Trial Evaluating Toxicity of SBRT and LDRB in Localized Prostate Cancer.

Prostate Cancer

Canada
Yonggao Mou
The First Affiliated Hospital of Nanchang University

Recruiting

Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen

Glioblastoma

China
University of Pennsylvania
Novartis

Active, not recruiting

Up-front CART-BCMA With or Without huCART19 in High-risk Multiple Myeloma

Multiple Myeloma

United States
Frederick R. Ueland, M.D.
ArtemiLife

Completed

Phase 1 Dose Escalation of ArtemiCoffee

Ovarian Cancer

United States
Providence Health & Services
Prometheus Laboratories; Cytokine Working Group

Active, not recruiting

Study of High Dose Interleukin-2 (IL-2) and Stereotactic Body Radiation (SBRT) in Patients With Metastatic Renal Cancer

Renal Cell Carcinoma

United States
Bexion Pharmaceuticals, Inc.
CTI Clinical Trial and Consulting Services

Terminated

A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) (KONQUER)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
MedSIR

Completed

Molecular Mechanisms of Resistance and Sensitivity to Palbociclib Re-challenge in ER+ mBC (BioPER)

Metastatic Breast Cancer

Spain, Italy
Shire

Completed

Study of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks in Japanese Subjects With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
Otsuka Beijing Research Institute

Terminated

The Safety and Efficacy of Brexpiprazole as Adjunctive Therapy in the Treatment of Major Depressive Disorder

Major Depressive Disorder

China
Takeda

Completed

Safety and Immunogenicity With Two Different Serotype 2 Potencies of Takeda's Tetravalent Dengue Vaccine Candidate (TDV) in Adults in Singapore

Dengue Fever

Singapore
Merck Sharp & Dohme LLC

Completed

Study of the Efficacy and Safety of SCH 619734 in Subjects With Chronic Cough From an Unknown Cause (Study P04888)

Cough
Consorci Sanitari Integral

Active, not recruiting

Breathing Pattern Description in Pneumonia Patients

Acute Respiratory Failure (ARF)

Spain
Glaukos Corporation

Active, not recruiting

Travoprost Intraocular Implant in Conjunction With Cataract Surgery

Ocular Hypertension | Open Angle Glaucoma

Armenia
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Study of Belantamab Mafodotin in Combination With Nirogacestat and Pomalidomide in People With Multiple Myeloma That Has Not Responded to Treatment or Has Come Back After Treatment

Multiple Myeloma

United States
Precision BioSciences, Inc.

Terminated

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States
US Oncology Research
Novartis Pharmaceuticals

Completed

Miracle Mouthwash Plus Hydrocortisone vs Prednisolone Mouth Rinse for Mouth Sores Caused by Everolimus

Stomatitis | Oral Mucositis | Malignant Tumor of Breast | Neoplasm of the Breast

United States
Feng Gao
Sichuan Provincial People's Hospital

Not yet recruiting

A Response Surface Analysis for the Interaction Between Ciprofol and Sevoflurane

Induction of General Anesthesia
Alliance Foundation Trials, LLC.
Patient-Centered Outcomes Research Institute

Completed

Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer (CANVAS)

Cancer | Venous Thromboembolism | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE) | Blood Clot

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Comparison of 2 Treatment Regimens for Eradication of P Aeruginosa Infection in Children With Cystic Fibrosis (CCTOBI)

Cystic Fibrosis

Belgium
Children's Hospital Medical Center, Cincinnati
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Recruiting

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study (PLUMM)

Lupus Nephritis

United States
Rose Pharma Inc

Completed

Effect of GLP-1 Analogue ROSE-010 on Appetite in Overweight and Obese Subjects

Obesity; Overweight

United States
Istituto Clinico Humanitas

Unknown

Immunogenic Cell Death as a Novel Mechanism of Mitomycin C Activity in Bladder Cancer (ICH-MIM-01)

Bladder Cancer

Italy

Search clinical trials for: Dose decrease

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