GI Consequences Economic Evaluation (GICEE)

The number of people who survive cancer has tripled in the past 30 years; however, chronic physical consequences of treatment for cancer adversely affect the quality of life of 20-25% of survivors. The largest group of patients reporting debilitating chronic side effects are those treated with radiotherapy alone or in combination with other treatments for pelvic cancer. Gastrointestinal symptoms are the most common chronic physical side effects reported, and have the greatest effect on daily activity. Overall, 50% of patients report that that their gastrointestinal symptoms affect their quality of life, and 20-40% state that this effect is moderate or severe. Such problems include chronic faecal incontinence (up to 60% of patients) after radiotherapy for prostate or rectal cancer (53, 54), and chronic loose stool (47%), defaecatory urgency (29%), or chronic abdominal pain (17%) after radiotherapy for gynecological cancer.

In 2010, the UK National Cancer Survivorship Initiative Vision challenged professionals to develop new models of care for patients because "the needs of cancer survivors are not being met, that being 'cured' of cancer does not necessarily equate with being well and that chronic consequences of treatment can have a devastating impact on daily life". The National Cancer Survivorship Initiative accepts that currently there is limited access to specialist services, despite an estimated 90,000 people in the UK experiencing long-term gastrointestinal problems as a consequence of cancer treatment. Furthermore, recent surveys of clinical oncologists and gastroenterologists concur with this sentiment, highlighting a lack of available expertise; with two UK audits of gastroenterology consultants and oncologists demonstrating no improvement in provision of specialist services between 2003 to 2010. Whilst NHS Improvement has developed stratified pathways of care, the Roadmap for Recovery report created recently by the Anthony Nolan Bone Marrow Transplant charity underlined the ongoing issue of lack of specialised commissioning of services for complex consequences of cancer treatment. It is estimated that £40 million (DoH) is wasted annually in futile and dangerous treatments for Pelvic Radiation Disease alone; academic estimates suggest this is closer to £80 million . Furthermore the incapacitating affects of GI symptoms leads to both loss of productivity and huge social costs. Currently there is no NHS tariff payable for GI consequences of cancer treatment; however the mean cost per completed episode of care by the GIANT (Gastrointestinal and Nutrition Team) service was calculated, amounting to an average cost of £1563 per patient. This can be compared to a tariff of £14,800 per woman treated with chemo-radiation for cervical cancer, and a cost in excess of £45,000 for a person with rectal cancer treated with long course chemo-radiation followed by surgery and adjuvant chemotherapy. With specialist clinics lacking, it can be assumed that the majority of people living with GI consequences of cancer treatment are being treated by their GPs; however, the Quality and Outcomes Framework by which GP Surgeries are measured and awarded financial incentives includes no domain or measure for gastrointestinal problems; and there have been no studies into the cost of managing patients with GI problems as a consequence of cancer treatment outside of the GIANT service. This exploratory study is a step in this direction.