Kemoterapi og strålebehandling efter operation til behandling af patienter med mave- eller spiserørskræft
28. april 2020 opdateret af: Alliance for Clinical Trials in Oncology
Fase III intergruppeforsøg med adjuverende kemoradiation efter resektion af gastrisk eller gastroøsofagealt adenokarcinom
RATIONALE: Lægemidler, der bruges i kemoterapi, bruger forskellige måder til at forhindre tumorceller i at dele sig, så de holder op med at vokse eller dør. Strålebehandling bruger højenergi røntgenstråler til at beskadige tumorceller. Kombination af kemoterapi med strålebehandling efter operationen kan dræbe eventuelle resterende tumorceller efter operationen. Det vides endnu ikke, hvilken kemoterapi- og strålebehandlingsregime, der er mere effektiv til behandling af mave- eller spiserørskræft.
FORMÅL: Randomiseret fase III-forsøg til at sammenligne to forskellige kemoterapi- og strålebehandlingsregimer til behandling af patienter, der er blevet opereret for mave- eller spiserørskræft.
Studieoversigt
Status
Afsluttet
Betingelser
Detaljeret beskrivelse
MÅL:
- Sammenlign den samlede overlevelse hos patienter med resekeret gastrisk adenocarcinom behandlet med epirubicin, cisplatin og infusionsfluorouracil (5-FU) vs 5-FU bolus og leucovorin calcium før og efter 5-FU plus strålebehandling.
- Sammenlign sygdomsfri overlevelse og lokale og fjerntliggende tilbagefaldsrater hos disse patienter behandlet med disse regimer.
- Korreler ekspressionen af formodede prognostiske markører (herunder TS, ERCC-1, MSI, E-cadherin, EGFR, p27, COX-2 og c-erbB-2) med den samlede overlevelse af patienter behandlet med disse regimer.
- Korreler specifikke kimlinjepolymorfier relateret til kemoterapimetabolisme og -resistens (herunder UGT2B7 [epirubicin], GST [cisplatin], ERCCI [cisplatin], XRCC1 [cisplatin], TS [5-FU], DPD [5-FU] og EGFR-polymorfier) med behandlingsrelateret toksicitet og samlet overlevelse af disse patienter.
- Korreler serumniveauer af insulinlignende vækstfaktor-1 (IGF-1), IGF-2 og IGF-bindende protein 3 med den samlede overlevelse af patienter behandlet med disse regimer.
OVERSIGT: Dette er en randomiseret, multicenter undersøgelse. Patienterne stratificeres efter dybden af tumorpenetration (T1 eller T2 vs. T3 vs. T4), lymfeknudepåvirkning (0 vs. 1-3) og omfanget af lymfadenektomi (D1 eller D2 vs. D0 eller ukendt). Patienterne randomiseres til 1 ud af 2 behandlingsarme.
- Arm I: Patienter får leucovorin calcium IV og fluorouracil (5-FU) IV på dag 1-5 i kursus 1, 3 og 4. Kurser gentages hver 28. dag. Under forløb 2 gennemgår patienter strålebehandling 5 dage om ugen og får 5-FU IV kontinuerligt i 5 uger. Patienterne hviler i 28-35 dage mellem kursus 2 og 3.
- Arm II: Patienterne får epirubicin IV over 3-15 minutter og cisplatin IV over 1 time på dag 1 og 5-FU IV kontinuerligt på dag 1-21 under forløb 1. Begyndende 1 uge senere får patienterne strålebehandling 5 dage om ugen og får 5-FU IV kontinuerligt i 5 uger. Patienterne hviler i 28-35 dage, før de påbegynder kursus 2 med kemoterapi. Patienterne får derefter epirubicin, cisplatin og 5-FU som i forløb 1. Behandlingen gentages hver 21. dag i 2 forløb.
Patienterne følges hver 3. måned i 2 år, hver 4. måned i 2 år og derefter årligt i 3 år.
PROJEKTERET TILSLUTNING: I alt 824 patienter vil blive akkumuleret til denne undersøgelse.
Undersøgelsestype
Interventionel
Tilmelding (Faktiske)
546
Fase
- Fase 3
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
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Alberta
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Edmonton, Alberta, Canada, T6G 1Z2
- Cross Cancer Institute at University of Alberta
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Manitoba
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Winnipeg, Manitoba, Canada, R3E 0V9
- CancerCare Manitoba
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New Brunswick
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Saint John, New Brunswick, Canada, E2L 4L2
- Saint John Regional Hospital
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Ontario
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Hamilton, Ontario, Canada, L8V 5C2
- Margaret and Charles Juravinski Cancer Centre
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Kingston, Ontario, Canada, K7L 5P9
- Cancer Centre of Southeastern Ontario at Kingston General Hospital
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London, Ontario, Canada, N6A 4L6
- London Regional Cancer Program at London Health Sciences Centre
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Ottawa, Ontario, Canada, K1H 1C4
- Ottawa Hospital Regional Cancer Centre - General Campus
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Saskatchewan
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Regina, Saskatchewan, Canada, S4T 7T1
- Allan Blair Cancer Centre at Pasqua Hospital
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Alabama
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Anniston, Alabama, Forenede Stater, 36202
- Regional Medical Center
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Mobile, Alabama, Forenede Stater, 36608
- Providence Cancer Center at Providence Hospital
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Arizona
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Scottsdale, Arizona, Forenede Stater, 85259-5499
- Mayo Clinic Scottsdale
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Tucson, Arizona, Forenede Stater, 85724-5024
- Arizona Cancer Center at University of Arizona Health Sciences Center
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Arkansas
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Fort Smith, Arkansas, Forenede Stater, 72903
- Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
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Jonesboro, Arkansas, Forenede Stater, 72401-9320
- Ben E. Owens Cancer Treatment Center at St. Bernard's Medical Center
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Little Rock, Arkansas, Forenede Stater, 72205
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
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California
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Antioch, California, Forenede Stater, 94531
- Kaiser Permanente - Deer Valley
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Burbank, California, Forenede Stater, 91505
- Providence Saint Joseph Medical Center - Burbank
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Castro Valley, California, Forenede Stater, 94546
- East Bay Radiation Oncology Center
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Castro Valley, California, Forenede Stater, 94546
- Eden Medical Center
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Castro Valley, California, Forenede Stater, 94546
- Valley Medical Oncology Consultants - Castro Valley
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Duarte, California, Forenede Stater, 91010-3000
- City of Hope Comprehensive Cancer Center
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Fremont, California, Forenede Stater, 94538
- Kaiser Permanente - Fremont
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Fremont, California, Forenede Stater, 94538
- Valley Medical Oncology
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Glendale, California, Forenede Stater, 91204
- Glendale Memorial Hospital Comprehensive Cancer Center
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Hayward, California, Forenede Stater, 94545
- Kaiser Permanente Medical Center - Hayward
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La Jolla, California, Forenede Stater, 92093-0658
- Rebecca and John Moores UCSD Cancer Center
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Martinez, California, Forenede Stater, 94553-3156
- Contra Costa Regional Medical Center
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Modesto, California, Forenede Stater, 95355
- Memorial Medical Center
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Monterey, California, Forenede Stater, 93940
- Community Hospital of the Monterey Peninsula Comprehensive Cancer Center
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Mountain View, California, Forenede Stater, 94040
- El Camino Hospital Cancer Center
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Mountain View, California, Forenede Stater, 94040
- Camino Medical Group - Treatment Center
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Oakland, California, Forenede Stater, 94609
- Alta Bates Summit Medical Center - Summit Campus
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Oakland, California, Forenede Stater, 94602
- Highland General Hospital
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Oakland, California, Forenede Stater, 94609
- Larry G Strieff MD Medical Corporation
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Oakland, California, Forenede Stater, 94609
- CCOP - Bay Area Tumor Institute
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Oakland, California, Forenede Stater, 94609
- Bay Area Breast Surgeons, Incorporated
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Oakland, California, Forenede Stater, 94609
- Tom K Lee, Incorporated
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Oakland, California, Forenede Stater, 94611
- Kaiser Permanente Medical Center - Oakland
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Pleasanton, California, Forenede Stater, 94588
- Valley Care Medical Center
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Pleasanton, California, Forenede Stater, 94588
- Valley Medical Oncology Consultants - Pleasanton
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Redwood City, California, Forenede Stater, 94063
- Kaiser Permanente Medical Center - Redwood City
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Richmond, California, Forenede Stater, 94801
- Kaiser Permanente Medical Center - Richmond
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Roseville, California, Forenede Stater, 95661
- Kaiser Permanente Medical Center - Roseville
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Sacramento, California, Forenede Stater, 95823
- South Sacramento Kaiser-Permanente Medical Center
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Sacramento, California, Forenede Stater, 95825
- Kaiser Permanente Medical Center - Sacramento
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San Francisco, California, Forenede Stater, 94115
- Kaiser Permanente Medical Center - San Francisco Geary Campus
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San Francisco, California, Forenede Stater, 94110
- San Francisco General Hospital Medical Center
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San Jose, California, Forenede Stater, 95119
- Kaiser Permanente Medical Center - Santa Teresa
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San Pablo, California, Forenede Stater, 94806
- Doctors Medical Center - San Pablo Campus
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San Rafael, California, Forenede Stater, 94903
- Kaiser Foundation Hospital - San Rafael
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Santa Clara, California, Forenede Stater, 95051
- Kaiser Permanente Medical Center - Santa Clara Kiely Campus
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Santa Rosa, California, Forenede Stater, 95403
- Kaiser Permanente Medical Center - Santa Rosa
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South San Francisco, California, Forenede Stater, 94080
- Kaiser Permanente Medical Center - South San Francisco
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Stockton, California, Forenede Stater, 95210
- Kaiser Permanente Medical Facility - Stockton
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Vallejo, California, Forenede Stater, 94589
- Kaiser Permanente Medical Center - Vallejo
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Walnut Creek, California, Forenede Stater, 94596
- Kaiser Permanente Medical Center - Walnut Creek
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Colorado
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Aurora, Colorado, Forenede Stater, 80012
- Aurora Presbyterian Hospital
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Boulder, Colorado, Forenede Stater, 80301-9019
- Boulder Community Hospital
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Colorado Springs, Colorado, Forenede Stater, 80933
- Penrose Cancer Center at Penrose Hospital
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Colorado Springs, Colorado, Forenede Stater, 80909
- Memorial Hospital Cancer Center - Colorado Springs
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Denver, Colorado, Forenede Stater, 80210
- Porter Adventist Hospital
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Denver, Colorado, Forenede Stater, 80220
- Rose Medical Center
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Denver, Colorado, Forenede Stater, 80218
- Presbyterian - St. Luke's Medical Center
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Denver, Colorado, Forenede Stater, 80204
- St. Anthony Central Hospital
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Denver, Colorado, Forenede Stater, 80218
- St. Joseph Hospital
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Denver, Colorado, Forenede Stater, 80224-2522
- CCOP - Colorado Cancer Research Program
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Englewood, Colorado, Forenede Stater, 80110
- Swedish Medical Center
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Grand Junction, Colorado, Forenede Stater, 81502
- St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
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Greeley, Colorado, Forenede Stater, 80631
- North Colorado Medical Center
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Lone Tree, Colorado, Forenede Stater, 80124
- Sky Ridge Medical Center
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Longmont, Colorado, Forenede Stater, 80501
- Hope Cancer Care Center at Longmont United Hospital
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Loveland, Colorado, Forenede Stater, 80539
- McKee Medical Center
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Pueblo, Colorado, Forenede Stater, 81004
- St. Mary - Corwin Regional Medical Center
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Thornton, Colorado, Forenede Stater, 80229
- North Suburban Medical Center
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Wheat Ridge, Colorado, Forenede Stater, 80033
- Exempla Lutheran Medical Center
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Connecticut
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Danbury, Connecticut, Forenede Stater, 06810
- Praxair Cancer Center at Danbury Hospital
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Hartford, Connecticut, Forenede Stater, 06102-5037
- Helen and Harry Gray Cancer Center at Hartford Hospital
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Delaware
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Lewes, Delaware, Forenede Stater, 19958
- Tunnell Cancer Center at Beebe Medical Center
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Newark, Delaware, Forenede Stater, 19713
- CCOP - Christiana Care Health Services
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District of Columbia
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Washington, District of Columbia, Forenede Stater, 20007
- Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
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Washington, District of Columbia, Forenede Stater, 20307-5001
- Walter Reed Army Medical Center
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Florida
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Boca Raton, Florida, Forenede Stater, 33486
- Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus
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Fort Lauderdale, Florida, Forenede Stater, 33316
- Broward General Medical Center Cancer Center
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Fort Lauderdale, Florida, Forenede Stater, 33308
- Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
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Hollywood, Florida, Forenede Stater, 33021
- Memorial Cancer Institute at Memorial Regional Hospital
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Jacksonville, Florida, Forenede Stater, 32207
- Baptist Cancer Institute - Jacksonville
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Jupiter, Florida, Forenede Stater, 33458
- Ella Milbank Foshay Cancer Center at Jupiter Medical Center
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Lakeland, Florida, Forenede Stater, 33805
- Center for Cancer Care and Research at Watson Clinic, LLP
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Miami Beach, Florida, Forenede Stater, 33140
- CCOP - Mount Sinai Medical Center
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Pensacola, Florida, Forenede Stater, 32504
- Sacred Heart Cancer Center at Sacred Heart Hospital
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Pensacola, Florida, Forenede Stater, 32514
- West Florida Cancer Institute at West Florida Hospital - Pensacola
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Weston, Florida, Forenede Stater, 33331
- Cleveland Clinic Florida - Weston
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Georgia
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Albany, Georgia, Forenede Stater, 31701
- Phoebe Cancer Center at Phoebe Putney Memorial Hospital
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Atlanta, Georgia, Forenede Stater, 30322
- Winship Cancer Institute of Emory University
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Decatur, Georgia, Forenede Stater, 30033
- Veterans Affairs Medical Center - Atlanta (Decatur)
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Macon, Georgia, Forenede Stater, 31208
- Medical Center of Central Georgia
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Savannah, Georgia, Forenede Stater, 31403-3089
- Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
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Savannah, Georgia, Forenede Stater, 31405
- Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
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Idaho
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Boise, Idaho, Forenede Stater, 83712
- Mountain States Tumor Institute at St. Luke's Regional Medical Center
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Illinois
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Aurora, Illinois, Forenede Stater, 60504
- Rush-Copley Cancer Care Center
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Berwyn, Illinois, Forenede Stater, 60402
- Hematology Oncology Associates of Illinois - Berwyn
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Chicago, Illinois, Forenede Stater, 60637-1470
- University of Chicago Cancer Research Center
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Chicago, Illinois, Forenede Stater, 60611-3013
- Robert H. Lurie Comprehensive Cancer Center at Northwestern University
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Chicago, Illinois, Forenede Stater, 60612-7243
- University of Illinois Cancer Center
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Chicago, Illinois, Forenede Stater, 60611
- Hematology and Oncology Associates
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Chicago, Illinois, Forenede Stater, 60657
- Creticos Cancer Center at Advocate Illinois Masonic Medical Center
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Chicago, Illinois, Forenede Stater, 60612
- Veterans Affairs Medical Center - Chicago Westside Hospital
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Chicago, Illinois, Forenede Stater, 60631
- Resurrection Medical Center
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Decatur, Illinois, Forenede Stater, 62526
- Decatur Memorial Hospital Cancer Care Institute
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Effingham, Illinois, Forenede Stater, 62401
- St. Anthony's Memorial Hospital
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Elmhurst, Illinois, Forenede Stater, 60126
- Elmhurst Memorial Hospital
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Harvey, Illinois, Forenede Stater, 60426
- Ingalls Cancer Care Center at Ingalls Memorial Hospital
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Hines, Illinois, Forenede Stater, 60141
- Veterans Affairs Medical Center - Hines
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Joliet, Illinois, Forenede Stater, 60435
- Joliet Oncology-Hematology Associates, Limited - West
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Joliet, Illinois, Forenede Stater, 60432
- Midwest Center for Hematology/Oncology
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La Grange, Illinois, Forenede Stater, 60525
- La Grange Memorial Hospital
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Libertyville, Illinois, Forenede Stater, 60048
- North Shore Oncology and Hematology Associates, Limited - Libertyville
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Maywood, Illinois, Forenede Stater, 60153
- Cardinal Bernardin Cancer Center at Loyola University Medical Center
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Naperville, Illinois, Forenede Stater, 60540
- Edward Hospital Cancer Center
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Naperville, Illinois, Forenede Stater, 60540
- Hematology Oncology Consultants - Naperville
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Naperville, Illinois, Forenede Stater, 60563
- La Grange Oncology Associates - Geneva
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Niles, Illinois, Forenede Stater, 60714
- Cancer Care and Hematology Specialists of Chicagoland - Niles
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Oak Lawn, Illinois, Forenede Stater, 60453-2699
- Advocate Christ Medical Center
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Olympia Fields, Illinois, Forenede Stater, 60461
- Saint James Hospital and Health Centers Comprehensive Cancer Institute - Olympia Fields
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River Forest, Illinois, Forenede Stater, 60305
- West Suburban Center for Cancer Care
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Rockford, Illinois, Forenede Stater, 61104-2315
- Swedish-American Regional Cancer Center
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Skokie, Illinois, Forenede Stater, 60076
- Hematology Oncology Associates - Skokie
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Springfield, Illinois, Forenede Stater, 62781-0001
- Regional Cancer Center at Memorial Medical Center
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Urbana, Illinois, Forenede Stater, 61801
- Carle Cancer Center at Carle Foundation Hospital
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Urbana, Illinois, Forenede Stater, 61801
- CCOP - Carle Cancer Center
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Indiana
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Beech Grove, Indiana, Forenede Stater, 46107
- St. Francis Hospital and Health Centers - Beech Grove Campus
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Elkhart, Indiana, Forenede Stater, 46515
- Elkhart General Hospital
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Fort Wayne, Indiana, Forenede Stater, 46845
- Fort Wayne Medical Oncology and Hematology
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Indianapolis, Indiana, Forenede Stater, 46202-5289
- Indiana University Melvin and Bren Simon Cancer Center
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Indianapolis, Indiana, Forenede Stater, 46202
- William N. Wishard Memorial Hospital
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Kokomo, Indiana, Forenede Stater, 46904
- Howard Community Hospital
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La Porte, Indiana, Forenede Stater, 46350
- Center for Cancer Therapy at LaPorte Hospital and Health Services
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Michigan City, Indiana, Forenede Stater, 46360
- Saint Anthony Memorial Health Centers
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Muncie, Indiana, Forenede Stater, 47303-3499
- Cancer Center at Ball Memorial Hospital
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Muncie, Indiana, Forenede Stater, 47303
- Medical Consultants, PC at Ball Memorial Cancer Center
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Munster, Indiana, Forenede Stater, 46321
- Community Hospital
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Richmond, Indiana, Forenede Stater, 47374
- Reid Hospital & Health Care Services
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South Bend, Indiana, Forenede Stater, 46601
- Memorial Hospital of South Bend
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South Bend, Indiana, Forenede Stater, 46601
- CCOP - Northern Indiana CR Consortium
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South Bend, Indiana, Forenede Stater, 46617
- Saint Joseph Regional Medical Center
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South Bend, Indiana, Forenede Stater, 46617
- South Bend Clinic
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Iowa
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Ames, Iowa, Forenede Stater, 50010
- McFarland Clinic, PC
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Bettendorf, Iowa, Forenede Stater, 52722
- Hematology Oncology Associates of the Quad Cities
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Cedar Rapids, Iowa, Forenede Stater, 52402
- St. Luke's Hospital
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Cedar Rapids, Iowa, Forenede Stater, 52403
- Mercy Regional Cancer Center at Mercy Medical Center
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Cedar Rapids, Iowa, Forenede Stater, 52402
- Iowa Blood and Cancer Care
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Des Moines, Iowa, Forenede Stater, 50309
- CCOP - Iowa Oncology Research Association
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Des Moines, Iowa, Forenede Stater, 50309
- John Stoddard Cancer Center at Iowa Methodist Medical Center
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Des Moines, Iowa, Forenede Stater, 50309
- Medical Oncology and Hematology Associates at John Stoddard Cancer Center
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Des Moines, Iowa, Forenede Stater, 50314
- Medical Oncology and Hematology Associates at Mercy Cancer Center
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Des Moines, Iowa, Forenede Stater, 50314
- Mercy Cancer Center at Mercy Medical Center - Des Moines
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Des Moines, Iowa, Forenede Stater, 50316
- John Stoddard Cancer Center at Iowa Lutheran Hospital
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Des Moines, Iowa, Forenede Stater, 50307
- Mercy Capitol Hospital
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Iowa City, Iowa, Forenede Stater, 52242-1002
- Holden Comprehensive Cancer Center at University of Iowa
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Ottumwa, Iowa, Forenede Stater, 52501
- McCreery Cancer Center at Ottumwa Regional
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Sioux City, Iowa, Forenede Stater, 51101
- Siouxland Hematology-Oncology Associates, LLP
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Sioux City, Iowa, Forenede Stater, 51104
- St. Luke's Regional Medical Center
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Sioux City, Iowa, Forenede Stater, 51104
- Mercy Medical Center - Sioux City
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Waterloo, Iowa, Forenede Stater, 50702
- Covenant Cancer Treatment Center
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Waterloo, Iowa, Forenede Stater, 50701
- Cedar Valley Medical Specialists, PC - West Ridgeway Avenue
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West Des Moines, Iowa, Forenede Stater, 50266
- Medical Oncology and Hematology Associates - West Des Moines
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Kansas
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Chanute, Kansas, Forenede Stater, 66720
- Cancer Center of Kansas, PA - Chanute
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Dodge City, Kansas, Forenede Stater, 67801
- Cancer Center of Kansas, PA - Dodge City
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El Dorado, Kansas, Forenede Stater, 67042
- Cancer Center of Kansas, PA - El Dorado
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Fort Scott, Kansas, Forenede Stater, 66701
- Cancer Center of Kansas - Fort Scott
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Independence, Kansas, Forenede Stater, 67301
- Cancer Center of Kansas-Independence
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Kingman, Kansas, Forenede Stater, 67068
- Cancer Center of Kansas, PA - Kingman
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Lawrence, Kansas, Forenede Stater, 66044
- Lawrence Memorial Hospital
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Liberal, Kansas, Forenede Stater, 67901
- Southwest Medical Center
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Newton, Kansas, Forenede Stater, 67114
- Cancer Center of Kansas, PA - Newton
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Overland Park, Kansas, Forenede Stater, 66209
- Menorah Medical Center
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Parsons, Kansas, Forenede Stater, 67357
- Cancer Center of Kansas, PA - Parsons
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Pratt, Kansas, Forenede Stater, 67124
- Cancer Center of Kansas, PA - Pratt
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Salina, Kansas, Forenede Stater, 67042
- Cancer Center of Kansas, PA - Salina
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Salina, Kansas, Forenede Stater, 67401
- Tammy Walker Cancer Center at Salina Regional Health Center
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Shawnee Mission, Kansas, Forenede Stater, 66204
- Shawnee Mission Medical Center
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Topeka, Kansas, Forenede Stater, 66606
- Cotton-O'Neil Cancer Center
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Topeka, Kansas, Forenede Stater, 66606
- St. Francis Comprehensive Cancer Center
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Wellington, Kansas, Forenede Stater, 67152
- Cancer Center of Kansas, PA - Wellington
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Wichita, Kansas, Forenede Stater, 67214
- Wesley Medical Center
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Wichita, Kansas, Forenede Stater, 67208
- Cancer Center of Kansas, PA - Medical Arts Tower
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Wichita, Kansas, Forenede Stater, 67214
- Cancer Center of Kansas, PA - Wichita
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Wichita, Kansas, Forenede Stater, 67214
- CCOP - Wichita
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Wichita, Kansas, Forenede Stater, 67214
- Via Christi Cancer Center at Via Christi Regional Medical Center
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Wichita, Kansas, Forenede Stater, 67208
- Associates in Womens Health, PA - North Review
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Winfield, Kansas, Forenede Stater, 67156
- Cancer Center of Kansas, PA - Winfield
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Louisiana
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Baton Rouge, Louisiana, Forenede Stater, 70809
- Mary Bird Perkins Cancer Center - Baton Rouge
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Baton Rouge, Louisiana, Forenede Stater, 70809
- Ochsner Health Center - Bluebonnet
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Baton Rouge, Louisiana, Forenede Stater, 70806
- Pennington Cancer Center at Baton Rouge General
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Covington, Louisiana, Forenede Stater, 70433
- Ochsner Health Center - Covington
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Houma, Louisiana, Forenede Stater, 70360
- Terrebonne General Medical Center
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New Orleans, Louisiana, Forenede Stater, 70121
- CCOP - Ochsner
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New Orleans, Louisiana, Forenede Stater, 70112
- MBCCOP - LSU Health Sciences Center
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New Orleans, Louisiana, Forenede Stater, 70121
- Ochsner Cancer Institute at Ochsner Clinic Foundation
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New Orleans, Louisiana, Forenede Stater, 70112
- Medical Center of Louisiana - New Orleans
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Maryland
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Baltimore, Maryland, Forenede Stater, 21231-2410
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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Baltimore, Maryland, Forenede Stater, 21201
- Greenebaum Cancer Center at University of Maryland Medical Center
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Easton, Maryland, Forenede Stater, 21601
- Shore Regional Cancer Center at Memorial Hospital - Easton
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Elkton, Maryland, Forenede Stater, 21921
- Union Hospital Cancer Program at Union Hospital
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Kensington, Maryland, Forenede Stater, 20895
- Associates in Oncology and Hematology
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Rockville, Maryland, Forenede Stater, 20878
- Associates in Oncology and Hematology - Medical Center Drive
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Massachusetts
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Boston, Massachusetts, Forenede Stater, 02215
- Beth Israel Deaconess Medical Center
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Boston, Massachusetts, Forenede Stater, 02114
- Massachusetts General Hospital
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Boston, Massachusetts, Forenede Stater, 02115
- Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute
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Boston, Massachusetts, Forenede Stater, 02118
- Boston University Cancer Research Center
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Boston, Massachusetts, Forenede Stater, 02115
- Dana-Farber/Brigham and Women's Cancer Center
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Boston, Massachusetts, Forenede Stater, 02111
- Tufts-NEMC Cancer Center
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Brighton, Massachusetts, Forenede Stater, 02135-2997
- Caritas St. Elizabeth's Medical Center
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Burlington, Massachusetts, Forenede Stater, 01805
- Lahey Clinic Medical Center - Burlington
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Fall River, Massachusetts, Forenede Stater, 02721
- Hudner Oncology Center at Saint Anne's Hospital - Fall River
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Gloucester, Massachusetts, Forenede Stater, 01930
- Addison Gilbert Hospital
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Hyannis, Massachusetts, Forenede Stater, 02601
- Cape Cod Hospital
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Lowell, Massachusetts, Forenede Stater, 01854
- Lowell General Hospital
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Pittsfield, Massachusetts, Forenede Stater, 01201
- Berkshire Hematology Oncology, PC
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South Weymouth, Massachusetts, Forenede Stater, 02190
- South Shore Hospital
-
Taunton, Massachusetts, Forenede Stater, 02780
- Morton Hospital & Medical Center
-
-
Michigan
-
Adrian, Michigan, Forenede Stater, 49221
- Hickman Cancer Center at Bixby Medical Center
-
Ann Arbor, Michigan, Forenede Stater, 48109-0942
- University Of Michigan Comprehensive Cancer Center
-
Ann Arbor, Michigan, Forenede Stater, 48106-0995
- Saint Joseph Mercy Cancer Center
-
Ann Arbor, Michigan, Forenede Stater, 48106
- CCOP - Michigan Cancer Research Consortium
-
Battle Creek, Michigan, Forenede Stater, 49017
- Battle Creek Health System Cancer Care Center
-
Bay City, Michigan, Forenede Stater, 48708
- Bay Regional Medical Center
-
Big Rapids, Michigan, Forenede Stater, 49307
- Mecosta County Medical Center
-
Dearborn, Michigan, Forenede Stater, 48123-2500
- Oakwood Cancer Center at Oakwood Hospital and Medical Center
-
Escanaba, Michigan, Forenede Stater, 49431
- Green Bay Oncology, Limited - Escanaba
-
Flint, Michigan, Forenede Stater, 48503
- Hurley Medical Center
-
Flint, Michigan, Forenede Stater, 48503
- Genesys Hurley Cancer Institute
-
Grand Rapids, Michigan, Forenede Stater, 49503
- Butterworth Hospital at Spectrum Health
-
Grand Rapids, Michigan, Forenede Stater, 49503
- CCOP - Grand Rapids
-
Grand Rapids, Michigan, Forenede Stater, 49503
- Lacks Cancer Center at Saint Mary's Health Care
-
Grosse Pointe Woods, Michigan, Forenede Stater, 48236
- Van Elslander Cancer Center at St. John Hospital and Medical Center
-
Iron Mountain, Michigan, Forenede Stater, 49801
- Dickinson County Healthcare System
-
Jackson, Michigan, Forenede Stater, 49201
- Foote Memorial Hospital
-
Kalamazoo, Michigan, Forenede Stater, 49007
- Bronson Methodist Hospital
-
Kalamazoo, Michigan, Forenede Stater, 49001
- Borgess Medical Center
-
Kalamazoo, Michigan, Forenede Stater, 49007-3731
- West Michigan Cancer Center
-
Lambertville, Michigan, Forenede Stater, 48144
- Haematology-Oncology Associates of Ohio and Michigan, PC
-
Lansing, Michigan, Forenede Stater, 48912-1811
- Sparrow Regional Cancer Center
-
Livonia, Michigan, Forenede Stater, 48154
- St. Mary Mercy Hospital
-
Monroe, Michigan, Forenede Stater, 48162
- Community Cancer Center of Monroe
-
Monroe, Michigan, Forenede Stater, 48162
- Mercy Memorial Hospital - Monroe
-
Muskegon, Michigan, Forenede Stater, 49443
- Mercy General Health Partners
-
Pontiac, Michigan, Forenede Stater, 48341-2985
- St. Joseph Mercy Oakland
-
Port Huron, Michigan, Forenede Stater, 48060
- Mercy Regional Cancer Center at Mercy Hospital
-
Royal Oak, Michigan, Forenede Stater, 48073
- William Beaumont Hospital - Royal Oak Campus
-
Saginaw, Michigan, Forenede Stater, 48601
- Seton Cancer Institute at Saint Mary's - Saginaw
-
Saint Joseph, Michigan, Forenede Stater, 49085
- Lakeland Regional Cancer Care Center - St. Joseph
-
Saint Joseph, Michigan, Forenede Stater, 49085
- Oncology Care Associates, PLLC
-
Traverse City, Michigan, Forenede Stater, 49684
- Munson Medical Center
-
Warren, Michigan, Forenede Stater, 48093
- St. John Macomb Hospital
-
Wyoming, Michigan, Forenede Stater, 49519
- Metro Health Hospital
-
-
Minnesota
-
Alexandria, Minnesota, Forenede Stater, 56308
-
Burnsville, Minnesota, Forenede Stater, 55337
- Fairview Ridges Hospital
-
Coon Rapids, Minnesota, Forenede Stater, 55433
- Mercy and Unity Cancer Center at Mercy Hospital
-
Duluth, Minnesota, Forenede Stater, 55805
- CCOP - Duluth
-
Duluth, Minnesota, Forenede Stater, 55805-1983
- Duluth Clinic Cancer Center - Duluth
-
Duluth, Minnesota, Forenede Stater, 55805
- Miller - Dwan Medical Center
-
Edina, Minnesota, Forenede Stater, 55435
- Fairview Southdale Hospital
-
Fergus Falls, Minnesota, Forenede Stater, 56537
-
Fridley, Minnesota, Forenede Stater, 55432
- Mercy and Unity Cancer Center at Unity Hospital
-
Hutchinson, Minnesota, Forenede Stater, 55350
- Hutchinson Area Health Care
-
Litchfield, Minnesota, Forenede Stater, 55355
- Meeker County Memorial Hospital
-
Maplewood, Minnesota, Forenede Stater, 55109
- Minnesota Oncology Hematology, PA - Maplewood
-
Maplewood, Minnesota, Forenede Stater, 55109
- HealthEast Cancer Care at St. John's Hospital
-
Minneapolis, Minnesota, Forenede Stater, 55407
- Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
-
Minneapolis, Minnesota, Forenede Stater, 55455
- Masonic Cancer Center at University of Minnesota
-
Minneapolis, Minnesota, Forenede Stater, 55415
- Hennepin County Medical Center - Minneapolis
-
Robbinsdale, Minnesota, Forenede Stater, 55422-2900
- Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
-
Rochester, Minnesota, Forenede Stater, 55905
- Mayo Clinic Cancer Center
-
Saint Cloud, Minnesota, Forenede Stater, 56303
- CentraCare Clinic - River Campus
-
Saint Cloud, Minnesota, Forenede Stater, 56303
- Coborn Cancer Center
-
Saint Louis Park, Minnesota, Forenede Stater, 55416
- CCOP - Metro-Minnesota
-
Saint Louis Park, Minnesota, Forenede Stater, 55416
- Park Nicollet Cancer Center
-
Saint Paul, Minnesota, Forenede Stater, 55102
- United Hospital
-
Saint Paul, Minnesota, Forenede Stater, 55101
- Regions Hospital Cancer Care Center
-
Saint Paul, Minnesota, Forenede Stater, 55102
- HealthEast Cancer Care at St. Joseph's Hospital
-
Shakopee, Minnesota, Forenede Stater, 55379
- St. Francis Cancer Center at St. Francis Medical Center
-
Waconia, Minnesota, Forenede Stater, 55387
- Ridgeview Medical Center
-
Willmar, Minnesota, Forenede Stater, 56201
- Willmar Cancer Center at Rice Memorial Hospital
-
Woodbury, Minnesota, Forenede Stater, 55125
- Minnesota Oncology Hematology, PA - Woodbury
-
Woodbury, Minnesota, Forenede Stater, 55125
- HealthEast Cancer Care at Woodwinds Health Campus
-
-
Mississippi
-
Hattiesburg, Mississippi, Forenede Stater, 39401
- Hattiesburg Clinic, PA at Forrest General
-
Hattiesburg, Mississippi, Forenede Stater, 39402
- Hematology & Oncology Clinic
-
Pascagoula, Mississippi, Forenede Stater, 39581
- Regional Cancer Center at Singing River Hospital
-
-
Missouri
-
Columbia, Missouri, Forenede Stater, 65203
- Ellis Fischel Cancer Center at University of Missouri - Columbia
-
Independence, Missouri, Forenede Stater, 64050
- Independence Regional Health Center
-
Kansas City, Missouri, Forenede Stater, 64131
- CCOP - Kansas City
-
Kansas City, Missouri, Forenede Stater, 64116
- North Kansas City Hospital
-
Kansas City, Missouri, Forenede Stater, 64132
- Research Medical Center
-
Kansas City, Missouri, Forenede Stater, 64108
- Truman Medical Center - Hospital Hill
-
Kansas City, Missouri, Forenede Stater, 64111
- Saint Luke's Cancer Institute at Saint Luke's Hospital
-
Kansas City, Missouri, Forenede Stater, 64114
- St. Joseph Medical Center
-
Kansas City, Missouri, Forenede Stater, 64116
- Parvin Radiation Oncology
-
Liberty, Missouri, Forenede Stater, 64068
- Liberty Hospital
-
Saint Joseph, Missouri, Forenede Stater, 64506
- Heartland Regional Medical Center
-
Saint Louis, Missouri, Forenede Stater, 63131
- Missouri Baptist Cancer Center
-
Saint Louis, Missouri, Forenede Stater, 63141
- Arch Medical Services, Incorporated at Center for Cancer Care and Research
-
Saint Louis, Missouri, Forenede Stater, 63136
- Christian Hospital Northeast Cancer Care Center
-
Springfield, Missouri, Forenede Stater, 65802
- CCOP - Cancer Research for the Ozarks
-
Springfield, Missouri, Forenede Stater, 65804
- St. John's Regional Health Center
-
Springfield, Missouri, Forenede Stater, 65807
- Hulston Cancer Center at Cox Medical Center South
-
-
Montana
-
Billings, Montana, Forenede Stater, 59101
- CCOP - Montana Cancer Consortium
-
Billings, Montana, Forenede Stater, 59101
- Hematology-Oncology Centers of the Northern Rockies - Billings
-
Billings, Montana, Forenede Stater, 59101
- Northern Rockies Radiation Oncology Center
-
Billings, Montana, Forenede Stater, 59101
- St. Vincent Healthcare Cancer Care Services
-
Billings, Montana, Forenede Stater, 59107-7000
- Billings Clinic - Downtown
-
Butte, Montana, Forenede Stater, 59701
- St. James Healthcare Cancer Care
-
Great Falls, Montana, Forenede Stater, 59405
- Great Falls Clinic - Main Facility
-
Great Falls, Montana, Forenede Stater, 59405
-
Great Falls, Montana, Forenede Stater, 59405-5309
- Big Sky Oncology
-
Great Falls, Montana, Forenede Stater, 59405
- Sletten Cancer Institute at Benefis Healthcare
-
Havre, Montana, Forenede Stater, 59501
- Northern Montana Hospital
-
Kalispell, Montana, Forenede Stater, 59901
- Kalispell Regional Medical Center
-
Kalispell, Montana, Forenede Stater, 59901
- Glacier Oncology, PLLC
-
Kalispell, Montana, Forenede Stater, 59901
- Kalispell Medical Oncology at KRMC
-
Missoula, Montana, Forenede Stater, 59801
- Community Medical Center
-
Missoula, Montana, Forenede Stater, 59804
- Guardian Oncology and Center for Wellness
-
Missoula, Montana, Forenede Stater, 59807-7877
- Montana Cancer Specialists at Montana Cancer Center
-
Missoula, Montana, Forenede Stater, 59807
- Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
-
-
Nebraska
-
Kearney, Nebraska, Forenede Stater, 68848-1990
- Good Samaritan Cancer Center at Good Samaritan Hospital
-
Lincoln, Nebraska, Forenede Stater, 68510
- Cancer Resource Center - Lincoln
-
Omaha, Nebraska, Forenede Stater, 68106
- CCOP - Missouri Valley Cancer Consortium
-
Omaha, Nebraska, Forenede Stater, 68122
- Immanuel Medical Center
-
Omaha, Nebraska, Forenede Stater, 68124
- Alegant Health Cancer Center at Bergan Mercy Medical Center
-
Omaha, Nebraska, Forenede Stater, 68131-2197
- Creighton University Medical Center
-
Omaha, Nebraska, Forenede Stater, 68114
- Methodist Estabrook Cancer Center
-
-
Nevada
-
Las Vegas, Nevada, Forenede Stater, 89102
- University Medical Center of Southern Nevada
-
Las Vegas, Nevada, Forenede Stater, 89106
- CCOP - Nevada Cancer Research Foundation
-
-
New Hampshire
-
Manchester, New Hampshire, Forenede Stater, 03103
- Elliot Regional Cancer Center at Elliot Hospital
-
-
New Jersey
-
Edison, New Jersey, Forenede Stater, 08818
- John F. Kennedy Medical Center
-
Freehold, New Jersey, Forenede Stater, 07728
- CentraState Medical Center
-
Livingston, New Jersey, Forenede Stater, 07039
- St. Barnabas Medical Center Cancer Center
-
Marlton, New Jersey, Forenede Stater, 08053
- Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton
-
Morristown, New Jersey, Forenede Stater, 07962
- Carol G. Simon Cancer Center at Morristown Memorial Hospital
-
New Brunswick, New Jersey, Forenede Stater, 08903
- Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
-
Summit, New Jersey, Forenede Stater, 07902
- Overlook Hospital
-
Vineland, New Jersey, Forenede Stater, 08360
- Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare
-
Voorhees, New Jersey, Forenede Stater, 08043
- Cancer Institute of New Jersey at Cooper - Voorhees
-
Voorhees, New Jersey, Forenede Stater, 08043
- Fox Chase Virtua Health Cancer Program at Virtua West Jersey
-
-
New York
-
Bronx, New York, Forenede Stater, 10466
- Our Lady of Mercy Medical Center Comprehensive Cancer Center
-
Brooklyn, New York, Forenede Stater, 11203
- SUNY Downstate Medical Center
-
Brooklyn, New York, Forenede Stater, 11203
- Kings County Hospital Center
-
Buffalo, New York, Forenede Stater, 14215
- Veterans Affairs Medical Center - Buffalo
-
East Syracuse, New York, Forenede Stater, 13057
- CCOP - Hematology-Oncology Associates of Central New York
-
New York, New York, Forenede Stater, 10065
- Memorial Sloan-Kettering Cancer Center
-
New York, New York, Forenede Stater, 10035
- Ralph Lauren Center for Cancer Care and Prevention
-
Rochester, New York, Forenede Stater, 14642
- James P. Wilmot Cancer Center at University of Rochester Medical Center
-
Staten Island, New York, Forenede Stater, 10305
- Nalitt Cancer Institute at Staten Island University Hospital
-
Syracuse, New York, Forenede Stater, 13210
- SUNY Upstate Medical University Hospital
-
-
North Carolina
-
Asheville, North Carolina, Forenede Stater, 28801
- Mission Hospitals - Memorial Campus
-
Chapel Hill, North Carolina, Forenede Stater, 27599-7295
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
-
Charlotte, North Carolina, Forenede Stater, 28232-2861
- Blumenthal Cancer Center at Carolinas Medical Center
-
Charlotte, North Carolina, Forenede Stater, 28233-3549
- Presbyterian Cancer Center at Presbyterian Hospital
-
Goldsboro, North Carolina, Forenede Stater, 27534
- Wayne Memorial Hospital, Incorporated
-
Greenville, North Carolina, Forenede Stater, 27834
- Leo W. Jenkins Cancer Center at ECU Medical School
-
Kinston, North Carolina, Forenede Stater, 28501
- Kinston Medical Specialists
-
Pinehurst, North Carolina, Forenede Stater, 28374
- FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center
-
Rutherfordton, North Carolina, Forenede Stater, 28139
- Rutherford Hospital
-
Winston-Salem, North Carolina, Forenede Stater, 27157-1096
- Wake Forest University Comprehensive Cancer Center
-
-
North Dakota
-
Bismarck, North Dakota, Forenede Stater, 58501
- Bismarck Cancer Center
-
Bismarck, North Dakota, Forenede Stater, 58501
- Medcenter One Hospital Cancer Care Center
-
Bismarck, North Dakota, Forenede Stater, 58501
- Mid Dakota Clinic, PC
-
Bismarck, North Dakota, Forenede Stater, 58502
- St. Alexius Medical Center Cancer Center
-
Fargo, North Dakota, Forenede Stater, 58103
- Dakota Cancer Institute at Dakota Clinic - South University
-
Grand Forks, North Dakota, Forenede Stater, 58201
- Altru Cancer Center at Altru Hospital
-
-
Ohio
-
Akron, Ohio, Forenede Stater, 44307
- McDowell Cancer Center at Akron General Medical Center
-
Akron, Ohio, Forenede Stater, 44309-2090
- Summa Center for Cancer Care at Akron City Hospital
-
Bellefontaine, Ohio, Forenede Stater, 43311
- Mary Rutan Hospital
-
Bowling Green, Ohio, Forenede Stater, 43402
- Wood County Oncology Center
-
Canton, Ohio, Forenede Stater, 44710-1799
- Aultman Cancer Center at Aultman Hospital
-
Chillicothe, Ohio, Forenede Stater, 45601
- Adena Regional Medical Center
-
Cleveland, Ohio, Forenede Stater, 44109
- MetroHealth Cancer Care Center at MetroHealth Medical Center
-
Clyde, Ohio, Forenede Stater, 43410
- North Coast Cancer Care - Clyde
-
Columbus, Ohio, Forenede Stater, 43214-3998
- Riverside Methodist Hospital Cancer Care
-
Columbus, Ohio, Forenede Stater, 43222
- Mount Carmel Health - West Hospital
-
Columbus, Ohio, Forenede Stater, 43210-1240
- Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
-
Columbus, Ohio, Forenede Stater, 43215
- CCOP - Columbus
-
Columbus, Ohio, Forenede Stater, 43215
- Grant Medical Center Cancer Care
-
Columbus, Ohio, Forenede Stater, 43228
- Doctors Hospital at Ohio Health
-
Dayton, Ohio, Forenede Stater, 45428
- Veterans Affairs Medical Center - Dayton
-
Dayton, Ohio, Forenede Stater, 45405
- Grandview Hospital
-
Dayton, Ohio, Forenede Stater, 45406
- Good Samaritan Hospital
-
Dayton, Ohio, Forenede Stater, 45429
- CCOP - Dayton
-
Delaware, Ohio, Forenede Stater, 43015
- Grady Memorial Hospital
-
Elyria, Ohio, Forenede Stater, 44035
- Hematology Oncology Center
-
Findlay, Ohio, Forenede Stater, 45840
- Blanchard Valley Medical Associates
-
Franklin, Ohio, Forenede Stater, 45005-1066
- Middletown Regional Hospital
-
Kettering, Ohio, Forenede Stater, 45429
- Charles F. Kettering Memorial Hospital
-
Lancaster, Ohio, Forenede Stater, 43130
- Fairfield Medical Center
-
Lima, Ohio, Forenede Stater, 45804
- Lima Memorial Hospital
-
Lima, Ohio, Forenede Stater, 45801
- St. Rita's Medical Center
-
Marietta, Ohio, Forenede Stater, 45750
- Strecker Cancer Center at Marietta Memorial Hospital
-
Maumee, Ohio, Forenede Stater, 43537
- St. Luke's Hospital
-
Maumee, Ohio, Forenede Stater, 43537-1839
- Northwest Ohio Oncology Center
-
Newark, Ohio, Forenede Stater, 43055
- Licking Memorial Cancer Care Program at Licking Memorial Hospital
-
Oregon, Ohio, Forenede Stater, 43616
- St. Charles Mercy Hospital
-
Oregon, Ohio, Forenede Stater, 43616
- Toledo Clinic - Oregon
-
Salem, Ohio, Forenede Stater, 44460
- Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford
-
Sandusky, Ohio, Forenede Stater, 44870
- North Coast Cancer Care, Incorporated
-
Springfield, Ohio, Forenede Stater, 45505
- Community Hospital of Springfield and Clark County
-
Springfield, Ohio, Forenede Stater, 45504
- Mercy Medical Center
-
Sylvania, Ohio, Forenede Stater, 43560
- Flower Hospital Cancer Center
-
Tiffin, Ohio, Forenede Stater, 44883
- Mercy Hospital of Tiffin
-
Toledo, Ohio, Forenede Stater, 43608
- St. Vincent Mercy Medical Center
-
Toledo, Ohio, Forenede Stater, 43606
- Toledo Hospital
-
Toledo, Ohio, Forenede Stater, 43614
- Medical University of Ohio Cancer Center
-
Toledo, Ohio, Forenede Stater, 43617
- CCOP - Toledo Community Hospital
-
Toledo, Ohio, Forenede Stater, 43623
- Toledo Clinic, Incorporated - Main Clinic
-
Toledo, Ohio, Forenede Stater, 43623
- St. Anne Mercy Hospital
-
Troy, Ohio, Forenede Stater, 45373-1300
- UVMC Cancer Care Center at Upper Valley Medical Center
-
Wauseon, Ohio, Forenede Stater, 43567
- Fulton County Health Center
-
Westerville, Ohio, Forenede Stater, 43081
- Mount Carmel St. Ann's Cancer Center
-
Wilmington, Ohio, Forenede Stater, 45177
- Clinton Memorial Hospital
-
Wooster, Ohio, Forenede Stater, 44691
- Cancer Treatment Center
-
Xenia, Ohio, Forenede Stater, 45385
- Ruth G. McMillan Cancer Center at Greene Memorial Hospital
-
Zanesville, Ohio, Forenede Stater, 43701
- Genesis - Good Samaritan Hospital
-
-
Oklahoma
-
Lawton, Oklahoma, Forenede Stater, 73505
- Cleo Craig Cancer Research Clinic
-
Oklahoma City, Oklahoma, Forenede Stater, 73104
- Oklahoma University Cancer Institute
-
Oklahoma City, Oklahoma, Forenede Stater, 73120
- Cancer Care Associates - Mercy Campus
-
-
Oregon
-
Portland, Oregon, Forenede Stater, 97232
- Kaiser Permanente Health Care - Portland
-
Salem, Oregon, Forenede Stater, 97309-5014
- Salem Hospital Regional Cancer Care Services
-
-
Pennsylvania
-
Allentown, Pennsylvania, Forenede Stater, 18105
- Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
-
Beaver, Pennsylvania, Forenede Stater, 15009
- UPMC Cancer Center at Beaver Medical Center
-
Bethlehem, Pennsylvania, Forenede Stater, 18015
- St. Luke's Cancer Network at St. Luke's Hospital
-
Bryn Mawr, Pennsylvania, Forenede Stater, 19010
- Bryn Mawr Hospital
-
Clairton, Pennsylvania, Forenede Stater, 15025
- UPMC Cancer Center at Jefferson Regional Medical Center
-
Danville, Pennsylvania, Forenede Stater, 17822-0001
- Geisinger Cancer Institute at Geisinger Health
-
DuBois, Pennsylvania, Forenede Stater, 15801
- Oncology Hematology Associates of Northern Pennsylvania, PC at Hahne Regional Cancer Center
-
East Stroudsburg, Pennsylvania, Forenede Stater, 18301
- Dale and Frances Hughes Cancer Center at Pocono Medical Center
-
Easton, Pennsylvania, Forenede Stater, 18042
- Easton Regional Cancer Center at Easton Hospital
-
Greensburg, Pennsylvania, Forenede Stater, 15601
- UPMC Cancer Center - Arnold Palmer Pavilion
-
Hershey, Pennsylvania, Forenede Stater, 17033-0850
- Penn State Cancer Institute at Milton S. Hershey Medical Center
-
Johnstown, Pennsylvania, Forenede Stater, 15901
- UPMC Cancer Center at the John P. Murtha Pavilion
-
Langhorne, Pennsylvania, Forenede Stater, 19047
- St. Mary Regional Cancer Center
-
Lewistown, Pennsylvania, Forenede Stater, 17044
- Lewistown Hospital
-
Media, Pennsylvania, Forenede Stater, 19063
- Riddle Memorial Hospital Cancer Center
-
Moon, Pennsylvania, Forenede Stater, 15108
- UPMC - Moon
-
Natrona Heights, Pennsylvania, Forenede Stater, 15065
- UPMC Cancer Center - Natrona Heights
-
New Castle, Pennsylvania, Forenede Stater, 16105
- Jameson Memorial Hospital - North Campus
-
Paoli, Pennsylvania, Forenede Stater, 19301-1792
- Cancer Center of Paoli Memorial Hospital
-
Philadelphia, Pennsylvania, Forenede Stater, 19111-2497
- Fox Chase Cancer Center - Philadelphia
-
Philadelphia, Pennsylvania, Forenede Stater, 19104-4283
- Abramson Cancer Center of the University of Pennsylvania
-
Philadelphia, Pennsylvania, Forenede Stater, 19141
- Albert Einstein Cancer Center
-
Philadelphia, Pennsylvania, Forenede Stater, 19107-5541
- Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
-
Philadelphia, Pennsylvania, Forenede Stater, 19107
- Joan Karnell Cancer Center at Pennsylvania Hospital
-
Philadelphia, Pennsylvania, Forenede Stater, 19114
- Frankford Hospital Cancer Center - Torresdale Campus
-
Pittsburgh, Pennsylvania, Forenede Stater, 15232
- UPMC Cancer Centers
-
Pittsburgh, Pennsylvania, Forenede Stater, 15213-2582
- UPMC - Shadyside
-
Pittsburgh, Pennsylvania, Forenede Stater, 15215
- UPMC Cancer Center at UPMC St. Margaret
-
Pittsburgh, Pennsylvania, Forenede Stater, 15237
- UPMC Cancer Center at UPMC Passavant
-
Pittsburgh, Pennsylvania, Forenede Stater, 15219
- Mercy Cancer Institute at Mercy Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15243
- St. Clair Memorial Hospital Cancer Center
-
Sayre, Pennsylvania, Forenede Stater, 18840
- Guthrie Cancer Center at Guthrie Clinic Sayre
-
Scranton, Pennsylvania, Forenede Stater, 18501
- Mercy Hospital Cancer Center - Scranton
-
Scranton, Pennsylvania, Forenede Stater, 18508
- Hematology and Oncology Associates of Northeastern Pennsylvania
-
Sellersville, Pennsylvania, Forenede Stater, 18960
- Grand View Hospital
-
Seneca, Pennsylvania, Forenede Stater, 16346
- UPMC Cancer Center at UPMC Northwest
-
State College, Pennsylvania, Forenede Stater, 16803
- Mount Nittany Medical Center
-
State College, Pennsylvania, Forenede Stater, 16801
- Geisinger Medical Group - Scenery Park
-
Washington, Pennsylvania, Forenede Stater, 15301
- Washington Hospital Cancer Center
-
West Grove, Pennsylvania, Forenede Stater, 19390-9499
- Jennersville Regional Hospital
-
Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
- Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
-
Wynnewood, Pennsylvania, Forenede Stater, 19096
- Lankenau Cancer Center at Lankenau Hospital
-
Wynnewood, Pennsylvania, Forenede Stater, 19096
- CCOP - Main Line Health
-
-
Rhode Island
-
Cranston, Rhode Island, Forenede Stater, 02920
- Hematology and Oncology Associates of Rhode Island
-
Pawtucket, Rhode Island, Forenede Stater, 02860
- Memorial Hospital of Rhode Island
-
Warwick, Rhode Island, Forenede Stater, 02886
- Kent County Memorial Hospital
-
-
South Carolina
-
Anderson, South Carolina, Forenede Stater, 29621
- AnMed Cancer Center
-
Charleston, South Carolina, Forenede Stater, 29401
- Roper St. Francis Cancer Center at Roper Hospital
-
Greenville, South Carolina, Forenede Stater, 29615
- CCOP - Greenville
-
Spartanburg, South Carolina, Forenede Stater, 29303
- CCOP - Upstate Carolina
-
Spartanburg, South Carolina, Forenede Stater, 29303
- Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
-
-
South Dakota
-
Sioux Falls, South Dakota, Forenede Stater, 57105
- Avera Cancer Institute
-
Sioux Falls, South Dakota, Forenede Stater, 57105
- Medical X-Ray Center, PC
-
Sioux Falls, South Dakota, Forenede Stater, 57117-5039
- Sanford Cancer Center at Sanford USD Medical Center
-
-
Tennessee
-
Bristol, Tennessee, Forenede Stater, 37620
- Blue Ridge Medical Specialists, PC
-
Kingsport, Tennessee, Forenede Stater, 37662
- Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center
-
Knoxville, Tennessee, Forenede Stater, 37916
- Thompson Cancer Survival Center
-
-
Texas
-
Fort Sam Houston, Texas, Forenede Stater, 78234-6200
- Brooke Army Medical Center
-
Lackland Air Force Base, Texas, Forenede Stater, 78236
- Wilford Hall Medical Center
-
Laredo, Texas, Forenede Stater, 78041
- Doctor's Hospital of Laredo
-
Temple, Texas, Forenede Stater, 76508
- CCOP - Scott and White Hospital
-
-
Utah
-
American Fork, Utah, Forenede Stater, 84003
- American Fork Hospital
-
Cedar City, Utah, Forenede Stater, 84720
- Sandra L. Maxwell Cancer Center
-
Murray, Utah, Forenede Stater, 84157
- Jon and Karen Huntsman Cancer Center at Intermountain Medical Center
-
Ogden, Utah, Forenede Stater, 84403
- Val and Ann Browning Cancer Center at McKay-Dee Hospital Center
-
Provo, Utah, Forenede Stater, 84604
- Utah Valley Regional Medical Center - Provo
-
Saint George, Utah, Forenede Stater, 84770
- Dixie Regional Medical Center - East Campus
-
Salt Lake City, Utah, Forenede Stater, 84112
- Huntsman Cancer Institute at University of Utah
-
Salt Lake City, Utah, Forenede Stater, 84103
- LDS Hospital
-
Salt Lake City, Utah, Forenede Stater, 84106
- Utah Cancer Specialists at UCS Cancer Center
-
-
Virginia
-
Danville, Virginia, Forenede Stater, 24541
- Danville Regional Medical Center
-
Fredericksburg, Virginia, Forenede Stater, 22401
- Fredericksburg Oncology, Incorporated
-
Hampton, Virginia, Forenede Stater, 23666
- Virginia Oncology Associates - Hampton
-
Lynchburg, Virginia, Forenede Stater, 24501
- Lynchburg Hematology-Oncology Clinic
-
Norton, Virginia, Forenede Stater, 24273
- Southwest Virginia Regional Cancer Center at Wellmonth Health
-
Richmond, Virginia, Forenede Stater, 23298-0037
- Virginia Commonwealth University Massey Cancer Center
-
-
Washington
-
Bellingham, Washington, Forenede Stater, 98225
- St. Joseph Cancer Center
-
Bremerton, Washington, Forenede Stater, 98310
- Olympic Hematology and Oncology
-
Kennewick, Washington, Forenede Stater, 99336
- Columbia Basin Hematology
-
Seattle, Washington, Forenede Stater, 98104
- Harborview Medical Center
-
Seattle, Washington, Forenede Stater, 98104
- Fred Hutchinson Cancer Research Center
-
Seattle, Washington, Forenede Stater, 98104
- Minor and James Medical, PLLC
-
Seattle, Washington, Forenede Stater, 98112
- Group Health Central Hospital
-
Seattle, Washington, Forenede Stater, 98122-4307
- Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
-
Seattle, Washington, Forenede Stater, 98122
- Polyclinic First Hill
-
Seattle, Washington, Forenede Stater, 98195-6043
- University Cancer Center at University of Washington Medical Center
-
Spokane, Washington, Forenede Stater, 99202
- Cancer Care Northwest - Spokane South
-
Tacoma, Washington, Forenede Stater, 98431
- Madigan Army Medical Center - Tacoma
-
-
West Virginia
-
Charleston, West Virginia, Forenede Stater, 25304
- West Virginia University Health Sciences Center - Charleston
-
Huntington, West Virginia, Forenede Stater, 25701
- Edwards Comprehensive Cancer Center at Cabell Huntington Hospital
-
Parkersburg, West Virginia, Forenede Stater, 26102
- Community Comprehensive Cancer Center at Camden-Clark Memorial Hospital
-
Princeton, West Virginia, Forenede Stater, 24740
- Princeton Community Hospital
-
-
Wisconsin
-
Eau Claire, Wisconsin, Forenede Stater, 54701
- Marshfield Clinic Cancer Care at Regional Cancer Center
-
Green Bay, Wisconsin, Forenede Stater, 54307-3508
- St. Vincent Hospital Regional Cancer Center
-
Green Bay, Wisconsin, Forenede Stater, 54301-3526
- Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
-
Green Bay, Wisconsin, Forenede Stater, 54303
- Green Bay Oncology, Limited at St. Mary's Hospital
-
Green Bay, Wisconsin, Forenede Stater, 54303
- St. Mary's Hospital Medical Center - Green Bay
-
Marinette, Wisconsin, Forenede Stater, 54143
- Bay Area Cancer Care Center at Bay Area Medical Center
-
Marshfield, Wisconsin, Forenede Stater, 54449
- Marshfield Clinic - Marshfield Center
-
Milwaukee, Wisconsin, Forenede Stater, 53226
- Medical College of Wisconsin Cancer Center
-
Minocqua, Wisconsin, Forenede Stater, 54548
- Marshfield Clinic - Lakeland Center
-
Oconomowoc, Wisconsin, Forenede Stater, 53066
- Regional Cancer Center at Oconomowoc Memorial Hospital
-
Oconto Falls, Wisconsin, Forenede Stater, 54154
- Green Bay Oncology, Limited - Oconto Falls
-
Rhinelander, Wisconsin, Forenede Stater, 54501
- Ministry Medical Group at Saint Mary's Hospital
-
Rice Lake, Wisconsin, Forenede Stater, 54868
- Marshfield Clinic - Indianhead Center
-
Sturgeon Bay, Wisconsin, Forenede Stater, 54235
- Green Bay Oncology, Limited - Sturgeon Bay
-
Waukesha, Wisconsin, Forenede Stater, 53188
- Waukesha Memorial Hospital Regional Cancer Center
-
Weston, Wisconsin, Forenede Stater, 54476
- Marshfield Clinic - Weston Center
-
Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
- Marshfield Clinic - Wisconsin Rapids Center
-
-
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
18 år og ældre (Voksen, Ældre voksen)
Tager imod sunde frivillige
Ingen
Køn, der er berettiget til at studere
Alle
Beskrivelse
Nødvendige tumorparametre
1.1 Patienter skal have histologisk diagnosticeret adenocarcinom i maven eller den gastroøsofageale forbindelse. Adenocarcinomer i spiserøret, der ikke involverer den gastroøsofageale forbindelse, er ikke kvalificerede.
1.2 Patienterne skal have haft en bloc resektion af alle kendte tumorer. Den kirurgiske resektion skal være foretaget med en kurativ hensigt.
1.3 Patienter skal have tumorforlængelse ud over muscularis propria og/eller nodal involvering uden tegn på M1-sygdom.
- Patienter kan have stadier IB, hvis der er tegn på enten nodepositiv (N1) sygdom eller tumorforlængelse ud over muscularis propria (dvs. T1, N1, M0 patienter er kvalificerede, men patienter med T2, N0, M0 er kun tilladt, hvis der er forlængelse ud over muscularis propria).
- Patienter kan have stadier II, IIIA, IIIB eller stadier IV med M0 (dvs. T4N2M0).
- Trin 0, IA eller enhver fase med M1 er ikke tilladt. (se appendiks I for TNM iscenesættelsesvejledning).
1.4 Patienter med kendt ikke-resektioneret cancer, tilbagevendende cancer, mikroskopiske tegn på tumor ved den distale eller proksimale linie af mave-resektion, ikke-sammenhængende resektion af tumor eller M1 (metastatisk) sygdom er ikke kvalificerede.
Forudgående terapi
2.1 Ingen forudgående behandling (undtagen hormonel eller biologisk) for andre maligne sygdomme er tilladt undtagen for tilstrækkeligt behandlet basalcelle- eller pladecellehudkræft, non-invasivt carcinom in situ, som er blevet fuldstændigt resekeret, eller anden cancer, for hvilken patienten har været sygdomsfri i fem flere år.
2.2 Patienter, der tidligere har haft kemoterapi eller strålebehandling, er ikke kvalificerede.
Patientkarakteristika
3.1 Patienter skal have en ECOG (CTC) præstationsstatus på 0, 1 eller 2.
3.2 Patienter skal have et tilstrækkeligt samlet kalorieindtag for at give dem mulighed for at opretholde deres post-kirurgiske kropsvægt. Patienter skal have dokumentation for stabil vægt (eller mindre end 2 pund vægttab) i mindst en uge før registrering.
3.3 Alle patienter skal evalueres af en stråleonkolog (før indskrivning) for at sikre, at patienten er en passende kandidat til strålebehandling.
3.4 Patienter har muligvis ikke ensidig nyrefunktion (kun én fungerende nyre) som bestemt ved CT-scanning med kontrast, urogram, nyrescanning eller anden undersøgelse.
3.5 Gravide eller ammende kvinder må ikke deltage. Mænd og kvinder med reproduktionspotentiale må ikke deltage, medmindre de har indvilliget i at bruge en effektiv præventionsmetode eller praktisere afholdenhed, mens de er i denne undersøgelse.
- Virkningerne af terapeutisk strålebehandling er kendt for at være teratogene.
- Virkningerne af epirubicin, cisplatin og 5-FU på et menneskeligt foster i udvikling ved den anbefalede terapeutiske dosis er mindre kendt.
- Af denne grund, og fordi DNA-alkylerende midler vides at være teratogene, skal kvinder i den fødedygtige alder og mænd acceptere at bruge passende prævention (hormonel præventionsmetode eller barrieremetode til prævention) før studiestart og i løbet af undersøgelsens deltagelse.
- Hvis en kvinde bliver gravid eller har mistanke om, at hun er gravid, mens hun deltager i denne undersøgelse, skal hun straks informere sin behandlende læge. Da risikoen for toksicitet hos ammende spædbørn sekundært til epirubicin-, cisplatin- og 5-FU-behandling af moderen er ukendt, men kan være skadelig, bør amning afbrydes.
3.6 Patienter med nogen af følgende hjertesygdomme er ikke kvalificerede:
- Ukontrolleret højt blodtryk
- Ustabil angina
- Symptomatisk kongestiv hjertesvigt
- Myokardieinfarkt < 6 måneder før registrering
- Alvorlig ukontrolleret hjertearytmi
- New York Heart Association klassifikation III eller IV.
3.7 Ingen ukontrolleret alvorlig medicinsk eller psykiatrisk sygdom, som ville forhindre overholdelse af behandling eller tilstrækkeligt informeret samtykke.
3.8 Patienter med aktiv infektiøs proces er udelukket.
3.9 Patienter med grad 2 eller højere perifer neuropati ved baseline er ikke kvalificerede.
Påkrævede indledende laboratorieværdier:
- Granulocytter ≥ 1.500/μl
- Blodpladetal ≥ 100.000/μl
- Kreatinin ≤ 1,5 mg/dl
- Bilirubin ≤ 2,0 mg/dl
- AST ≤ 3x øvre normalgrænse
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Behandling
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Ingen (Åben etiket)
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
|
Aktiv komparator: Arm I
Patienter får leucovorin calcium IV og fluorouracil (5-FU) IV på dag 1-5 i kursus 1, 3 og 4. Kurser gentages hver 28. dag.
Under forløb 2 gennemgår patienter strålebehandling 5 dage om ugen og får 5-FU IV kontinuerligt i 5 til 6 uger.
Patienterne hviler i 28-35 dage mellem kursus 2 og 3.
|
Givet IV
Givet IV
Gives 5 dage om ugen i 5 uger
|
|
Eksperimentel: Arm II
Patienterne får epirubicin IV over 3-15 minutter og cisplatin IV over 1 time på dag 1 og 5-FU IV kontinuerligt på dag 1-21 under forløb 1. Begyndende 1 uge senere får patienterne strålebehandling 5 dage om ugen og 5-FU IV. kontinuerligt i 5 uger.
Patienterne hviler i 28-35 dage, før de påbegynder kursus 2 med kemoterapi.
Patienterne får derefter epirubicin, cisplatin og 5-FU som i forløb 1. Behandlingen gentages hver 21. dag i 2 forløb.
|
Givet IV
Givet IV
Givet IV
Gives 5 dage om ugen i 5 uger
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Samlet overlevelse
Tidsramme: Fra studieoptagelse til død uanset årsag; op til 3 år
|
Samlet overlevelse er defineret som tiden fra studieindskrivning til død på grund af en hvilken som helst årsag.
Fordelingen af overlevelsestid vil blive estimeret ved hjælp af metoden fra Kaplan-Meier.
|
Fra studieoptagelse til død uanset årsag; op til 3 år
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Sygdomsfri overlevelse
Tidsramme: Fra datoen for studietilmelding indtil dødsfald eller dokumenteret anden primær tumor eller recidiv af cancer; op til 4 år
|
Sygdomsfri overlevelse er defineret som tiden fra datoen for studieindskrivning til død eller dokumenteret anden primær tumor eller recidiv af cancer. Fordelingen af sygdomsfri overlevelsestid vil blive estimeret ved hjælp af Kaplan-Meiers metode.
|
Fra datoen for studietilmelding indtil dødsfald eller dokumenteret anden primær tumor eller recidiv af cancer; op til 4 år
|
Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Samarbejdspartnere
Efterforskere
- Studiestol: Charles Fuchs, MD, MPH, Dana-Farber Cancer Institute
Publikationer og nyttige links
Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.
Generelle publikationer
- Fuchs C, Tepper JE, Niedwiecki D, et al.: Postoperative adjuvant chemoradiation for gastric or gastroesophageal adenocarcinoma using epirubicin, cisplatin, and infusional (CI) 5-FU (ECF) before and after CI 5-FU and radiotherapy (RT): interim toxicity results from Intergroup trial CALGB 80101. [Abstract] American Society of Clinical Oncology 2006 Gastrointestinal Cancers Symposium, 26-28 January 2006, San Francisco, California. A-61, 2006.
- Patel JN, Jiang C, Owzar K, Mulkey F, Luzum JA, Mamon HJ, Haller DG, Dragovich T, Alberts SR, Bjarnason G, Willet CG, Niedzwiecki D, Enzinger P, Ratain MJ, Fuchs C, McLeod HL. Pharmacogenetic study in gastric cancer patients treated with adjuvant fluorouracil/leucovorin or epirubicin/cisplatin/fluorouracil before and after chemoradiation on CALGB 80101 (Alliance). Pharmacogenet Genomics. 2021 Dec 1;31(9):215-220. doi: 10.1097/FPC.0000000000000442.
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart
1. december 2002
Primær færdiggørelse (Faktiske)
1. juni 2012
Studieafslutning (Faktiske)
1. december 2016
Datoer for studieregistrering
Først indsendt
24. januar 2003
Først indsendt, der opfyldte QC-kriterier
26. januar 2003
Først opslået (Skøn)
27. januar 2003
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
7. maj 2020
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
28. april 2020
Sidst verificeret
1. april 2020
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
- Sygdomme i fordøjelsessystemet
- Neoplasmer
- Neoplasmer efter sted
- Gastrointestinale neoplasmer
- Neoplasmer i fordøjelsessystemet
- Gastrointestinale sygdomme
- Mavesygdomme
- Neoplasmer i hoved og hals
- Esophageale sygdomme
- Neoplasmer i maven
- Esophageale neoplasmer
- Lægemidlers fysiologiske virkninger
- Molekylære mekanismer for farmakologisk virkning
- Enzymhæmmere
- Antimetabolitter, Antineoplastisk
- Antimetabolitter
- Antineoplastiske midler
- Immunsuppressive midler
- Immunologiske faktorer
- Beskyttelsesagenter
- Topoisomerase II-hæmmere
- Topoisomerasehæmmere
- Mikronæringsstoffer
- Antibiotika, antineoplastisk
- Vitaminer
- Calciumregulerende hormoner og midler
- Modgift
- Vitamin B kompleks
- Cisplatin
- Fluorouracil
- Epirubicin
- Leucovorin
- Kalk
- Levoleucovorin
Andre undersøgelses-id-numre
- CALGB-80101
- U10CA031946 (U.S. NIH-bevilling/kontrakt)
- CDR0000258787 (Registry Identifier: NCI Physician Data Query)
Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .