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JUPITER - Crestor 20 mg versus placebo til forebyggelse af kardiovaskulære (CV) hændelser

6. februar 2014 opdateret af: AstraZeneca

Et randomiseret, dobbeltblindt, placebokontrolleret, multicenter, fase 3-studie af Rosuvastatin (CRESTOR®) 20 mg til forebyggelse af kardiovaskulære hændelser blandt forsøgspersoner med lave niveauer af lavdensitetslipoprotein (LDL) kolesterol og forhøjede niveauer af C-reaktivt protein

Formålet med denne undersøgelse er at bestemme sikkerheden og effektiviteten af ​​langtidsbehandling med rosuvastatin sammenlignet med placebo, og at vurdere, om behandling med rosuvastatin kan være effektiv til at reducere risikoen for større kardiovaskulære hændelser.

Studieoversigt

Status

Afsluttet

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

AstraZeneca meddelte, at det har besluttet at stoppe det kliniske CRESTOR JUPITER-studie tidligt baseret på en anbefaling fra et uafhængigt dataovervågningsråd og JUPITER-styringsudvalget, som mødtes den 29. marts 2008. Studiet vil blive stoppet tidligt, fordi der er utvetydige beviser for en reduktion i kardiovaskulær morbiditet og dødelighed blandt patienter, der fik CRESTOR sammenlignet med placebo.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

17802

Fase

  • Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

  • Argentina
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        • Research Site
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        • Research Site
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  • Danmark
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  • Den Russiske Føderation
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        • Research Site
      • Blue Ridge, Georgia, Forenede Stater
        • Research Site
      • Brunswick, Georgia, Forenede Stater
        • Research Site
      • Columbus, Georgia, Forenede Stater
        • Research Site
      • Conyers, Georgia, Forenede Stater
        • Research Site
      • Decatur, Georgia, Forenede Stater
        • Research Site
      • Fayetteville, Georgia, Forenede Stater
        • Research Site
      • Suwanee, Georgia, Forenede Stater
        • Research Site
      • Woodstock, Georgia, Forenede Stater
        • Research Site
    • Idaho
      • Idaho Falls, Idaho, Forenede Stater
        • Research Site
      • Meridian, Idaho, Forenede Stater
        • Research Site
    • Illinois
      • Aurora, Illinois, Forenede Stater
        • Research Site
      • Champaign, Illinois, Forenede Stater
        • Research Site
      • Chicago, Illinois, Forenede Stater
        • Research Site
      • Gurnee, Illinois, Forenede Stater
        • Research Site
      • Lake Road, Illinois, Forenede Stater
        • Research Site
      • Melrose Park, Illinois, Forenede Stater
        • Research Site
      • Morton, Illinois, Forenede Stater
        • Research Site
      • O'fallon, Illinois, Forenede Stater
        • Research Site
      • Orland Park, Illinois, Forenede Stater
        • Research Site
      • Springfield, Illinois, Forenede Stater
        • Research Site
      • Sterling, Illinois, Forenede Stater
        • Research Site
      • Vernon Hills, Illinois, Forenede Stater
        • Research Site
    • Indiana
      • Avon, Indiana, Forenede Stater
        • Research Site
      • Evansville, Indiana, Forenede Stater
        • Research Site
      • Granger, Indiana, Forenede Stater
        • Research Site
      • Indianapolis, Indiana, Forenede Stater
        • Research Site
      • Jeffersonville, Indiana, Forenede Stater
        • Research Site
      • Munster, Indiana, Forenede Stater
        • Research Site
      • Newburgh, Indiana, Forenede Stater
        • Research Site
      • Valparaiso, Indiana, Forenede Stater
        • Research Site
    • Iowa
      • Des Moines, Iowa, Forenede Stater
        • Research Site
      • Dubuque, Iowa, Forenede Stater
        • Research Site
      • Iowa City, Iowa, Forenede Stater
        • Research Site
      • West Des Moines, Iowa, Forenede Stater
        • Research Site
    • Kansas
      • Leavenworth, Kansas, Forenede Stater
        • Research Site
      • Olathe, Kansas, Forenede Stater
        • Research Site
      • Overland Park, Kansas, Forenede Stater
        • Research Site
      • Shawnee Mission, Kansas, Forenede Stater
        • Research Site
      • Topeka, Kansas, Forenede Stater
        • Research Site
      • Wichita, Kansas, Forenede Stater
        • Research Site
    • Kentucky
      • Evansville, Kentucky, Forenede Stater
        • Research Site
      • Lexington, Kentucky, Forenede Stater
        • Research Site
      • Louisville, Kentucky, Forenede Stater
        • Research Site
    • Louisiana
      • Baton Rouge, Louisiana, Forenede Stater
        • Research Site
      • Covington, Louisiana, Forenede Stater
        • Research Site
      • Houma, Louisiana, Forenede Stater
        • Research Site
      • Lake Charles, Louisiana, Forenede Stater
        • Research Site
      • Marrero, Louisiana, Forenede Stater
        • Research Site
      • New Orleans, Louisiana, Forenede Stater
        • Research Site
      • Shreveport, Louisiana, Forenede Stater
        • Research Site
    • Maine
      • Auburn, Maine, Forenede Stater
        • Research Site
      • Bangor, Maine, Forenede Stater
        • Research Site
      • Portland, Maine, Forenede Stater
        • Research Site
      • S Portland, Maine, Forenede Stater
        • Research Site
      • Sanford, Maine, Forenede Stater
        • Research Site
    • Maryland
      • Baltimore, Maryland, Forenede Stater
        • Research Site
      • Charlotte Hall, Maryland, Forenede Stater
        • Research Site
      • Glen Burnie, Maryland, Forenede Stater
        • Research Site
      • Hagerstown, Maryland, Forenede Stater
        • Research Site
      • Prince Frederick, Maryland, Forenede Stater
        • Research Site
      • Rockville, Maryland, Forenede Stater
        • Research Site
      • Towson, Maryland, Forenede Stater
        • Research Site
    • Massachusetts
      • Ayer, Massachusetts, Forenede Stater
        • Research Site
      • Boston, Massachusetts, Forenede Stater
        • Research Site
      • Burlington, Massachusetts, Forenede Stater
        • Research Site
      • East Bridgewater, Massachusetts, Forenede Stater
        • Research Site
      • Haverhill, Massachusetts, Forenede Stater
        • Research Site
      • Natick, Massachusetts, Forenede Stater
        • Research Site
      • Newton, Massachusetts, Forenede Stater
        • Research Site
      • Springfield, Massachusetts, Forenede Stater
        • Research Site
      • West Yarmouth, Massachusetts, Forenede Stater
        • Research Site
      • Worcester, Massachusetts, Forenede Stater
        • Research Site
    • Michigan
      • Berkley, Michigan, Forenede Stater
        • Research Site
      • Dearborn, Michigan, Forenede Stater
        • Research Site
      • Grand Rapids, Michigan, Forenede Stater
        • Research Site
      • Livonia, Michigan, Forenede Stater
        • Research Site
      • Petoskey, Michigan, Forenede Stater
        • Research Site
      • Portage, Michigan, Forenede Stater
        • Research Site
      • St. Joseph, Michigan, Forenede Stater
        • Research Site
      • Troy, Michigan, Forenede Stater
        • Research Site
      • Warren, Michigan, Forenede Stater
        • Research Site
    • Minnesota
      • Chaska, Minnesota, Forenede Stater
        • Research Site
      • Duluth, Minnesota, Forenede Stater
        • Research Site
      • Minneapolis, Minnesota, Forenede Stater
        • Research Site
      • Rochester, Minnesota, Forenede Stater
        • Research Site
      • St. Paul, Minnesota, Forenede Stater
        • Research Site
    • Mississippi
      • Gulfport, Mississippi, Forenede Stater
        • Research Site
      • Jackson, Mississippi, Forenede Stater
        • Research Site
      • Olive Branch, Mississippi, Forenede Stater
        • Research Site
      • Picayune, Mississippi, Forenede Stater
        • Research Site
      • Port Gibson, Mississippi, Forenede Stater
        • Research Site
    • Missouri
      • Chesterfield, Missouri, Forenede Stater
        • Research Site
      • Excelsior Springs, Missouri, Forenede Stater
        • Research Site
      • Jefferson City, Missouri, Forenede Stater
        • Research Site
      • Kansas City, Missouri, Forenede Stater
        • Research Site
      • Manchester, Missouri, Forenede Stater
        • Research Site
      • Mexico, Missouri, Forenede Stater
        • Research Site
      • Rolla, Missouri, Forenede Stater
        • Research Site
      • Shawnee Mission, Missouri, Forenede Stater
        • Research Site
      • Springfield, Missouri, Forenede Stater
        • Research Site
      • St Charles, Missouri, Forenede Stater
        • Research Site
      • St Louis, Missouri, Forenede Stater
        • Research Site
      • Washington, Missouri, Forenede Stater
        • Research Site
      • Wentzville, Missouri, Forenede Stater
        • Research Site
    • Montana
      • Anaconda, Montana, Forenede Stater
        • Research Site
      • Butte, Montana, Forenede Stater
        • Research Site
      • Kalispell, Montana, Forenede Stater
        • Research Site
      • Missoula, Montana, Forenede Stater
        • Research Site
    • Nebraska
      • Grand Island, Nebraska, Forenede Stater
        • Research Site
      • Omaha, Nebraska, Forenede Stater
        • Research Site
    • Nevada
      • Henderson, Nevada, Forenede Stater
        • Research Site
      • Las Vegas, Nevada, Forenede Stater
        • Research Site
      • Pahrump, Nevada, Forenede Stater
        • Research Site
    • New Hampshire
      • Nashua, New Hampshire, Forenede Stater
        • Research Site
    • New Jersey
      • Bloomfield, New Jersey, Forenede Stater
        • Research Site
      • Brick, New Jersey, Forenede Stater
        • Research Site
      • Cherry Hill, New Jersey, Forenede Stater
        • Research Site
      • Elizabeth, New Jersey, Forenede Stater
        • Research Site
      • Englewood Cliffs, New Jersey, Forenede Stater
        • Research Site
      • Morristown, New Jersey, Forenede Stater
        • Research Site
      • Newark, New Jersey, Forenede Stater
        • Research Site
      • Northbrunswick, New Jersey, Forenede Stater
        • Research Site
      • Passaic, New Jersey, Forenede Stater
        • Research Site
      • Teaneck, New Jersey, Forenede Stater
        • Research Site
      • Trenton, New Jersey, Forenede Stater
        • Research Site
      • West Caldwell, New Jersey, Forenede Stater
        • Research Site
    • New Mexico
      • Albuquerque, New Mexico, Forenede Stater
        • Research Site
      • Los Alamos, New Mexico, Forenede Stater
        • Research Site
      • Rio Rancho, New Mexico, Forenede Stater
        • Research Site
    • New York
      • Albany, New York, Forenede Stater
        • Research Site
      • Binghamton, New York, Forenede Stater
        • Research Site
      • Bowmansville, New York, Forenede Stater
        • Research Site
      • Bronx, New York, Forenede Stater
        • Research Site
      • Bronxville, New York, Forenede Stater
        • Research Site
      • Brooklyn, New York, Forenede Stater
        • Research Site
      • Buffalo, New York, Forenede Stater
        • Research Site
      • Camillus, New York, Forenede Stater
        • Research Site
      • E Syracuse, New York, Forenede Stater
        • Research Site
      • East Islip, New York, Forenede Stater
        • Research Site
      • Fayetteville, New York, Forenede Stater
        • Research Site
      • Lake Success, New York, Forenede Stater
        • Research Site
      • Mamaroneck, New York, Forenede Stater
        • Research Site
      • Mount Vernon, New York, Forenede Stater
        • Research Site
      • New Hartford, New York, Forenede Stater
        • Research Site
      • New Hyde Park, New York, Forenede Stater
        • Research Site
      • New York, New York, Forenede Stater
        • Research Site
      • Niagara Falls, New York, Forenede Stater
        • Research Site
      • Poughkeepsie, New York, Forenede Stater
        • Research Site
      • Riverhead, New York, Forenede Stater
        • Research Site
      • Rochester, New York, Forenede Stater
        • Research Site
      • Syracuse, New York, Forenede Stater
        • Research Site
      • Tonawanda, New York, Forenede Stater
        • Research Site
      • Williamsville, New York, Forenede Stater
        • Research Site
    • North Carolina
      • Asheville, North Carolina, Forenede Stater
        • Research Site
      • Burlington, North Carolina, Forenede Stater
        • Research Site
      • Cary, North Carolina, Forenede Stater
        • Research Site
      • Chapel Hill, North Carolina, Forenede Stater
        • Research Site
      • Charlotte, North Carolina, Forenede Stater
        • Research Site
      • Durham, North Carolina, Forenede Stater
        • Research Site
      • Fayetteville, North Carolina, Forenede Stater
        • Research Site
      • Lenoir, North Carolina, Forenede Stater
        • Research Site
      • Lexington, North Carolina, Forenede Stater
        • Research Site
      • Raleigh, North Carolina, Forenede Stater
        • Research Site
      • Statesville, North Carolina, Forenede Stater
        • Research Site
      • Winston-salem, North Carolina, Forenede Stater
        • Research Site
    • North Dakota
      • Fargo, North Dakota, Forenede Stater
        • Research Site
    • Ohio
      • Akron, Ohio, Forenede Stater
        • Research Site
      • Athens, Ohio, Forenede Stater
        • Research Site
      • Bellbrook, Ohio, Forenede Stater
        • Research Site
      • Canal Fulton, Ohio, Forenede Stater
        • Research Site
      • Centerville, Ohio, Forenede Stater
        • Research Site
      • Chesterland, Ohio, Forenede Stater
        • Research Site
      • Cincinnati, Ohio, Forenede Stater
        • Research Site
      • Columbus, Ohio, Forenede Stater
        • Research Site
      • Dayton, Ohio, Forenede Stater
        • Research Site
      • Mansfield, Ohio, Forenede Stater
        • Research Site
      • Massillon, Ohio, Forenede Stater
        • Research Site
      • Maumee, Ohio, Forenede Stater
        • Research Site
      • Wadsworth, Ohio, Forenede Stater
        • Research Site
      • Warren, Ohio, Forenede Stater
        • Research Site
      • Zanesville, Ohio, Forenede Stater
        • Research Site
    • Oklahoma
      • Guthrie, Oklahoma, Forenede Stater
        • Research Site
      • Muskogee, Oklahoma, Forenede Stater
        • Research Site
      • Oklahoma City, Oklahoma, Forenede Stater
        • Research Site
      • Tulsa, Oklahoma, Forenede Stater
        • Research Site
      • Yukon, Oklahoma, Forenede Stater
        • Research Site
    • Oregon
      • Corvallis, Oregon, Forenede Stater
        • Research Site
      • Dallas, Oregon, Forenede Stater
        • Research Site
      • Eugene, Oregon, Forenede Stater
        • Research Site
      • Lake Oswego, Oregon, Forenede Stater
        • Research Site
      • Medford, Oregon, Forenede Stater
        • Research Site
      • Milwaukie, Oregon, Forenede Stater
        • Research Site
      • Portland, Oregon, Forenede Stater
        • Research Site
      • Springfield, Oregon, Forenede Stater
        • Research Site
    • Pennsylvania
      • Altoona, Pennsylvania, Forenede Stater
        • Research Site
      • Beaver, Pennsylvania, Forenede Stater
        • Research Site
      • Bloomsburg, Pennsylvania, Forenede Stater
        • Research Site
      • Broomall, Pennsylvania, Forenede Stater
        • Research Site
      • Camp Hill, Pennsylvania, Forenede Stater
        • Research Site
      • Connellsville, Pennsylvania, Forenede Stater
        • Research Site
      • Downingtown, Pennsylvania, Forenede Stater
        • Research Site
      • Erie, Pennsylvania, Forenede Stater
        • Research Site
      • Feasterville, Pennsylvania, Forenede Stater
        • Research Site
      • Fleetwood, Pennsylvania, Forenede Stater
        • Research Site
      • Harleysville, Pennsylvania, Forenede Stater
        • Research Site
      • Harrisburg, Pennsylvania, Forenede Stater
        • Research Site
      • Jersey Shore, Pennsylvania, Forenede Stater
        • Research Site
      • King of Prussia, Pennsylvania, Forenede Stater
        • Research Site
      • Lansdale, Pennsylvania, Forenede Stater
        • Research Site
      • Lansdowne, Pennsylvania, Forenede Stater
        • Research Site
      • Lewisburg, Pennsylvania, Forenede Stater
        • Research Site
      • Lewistown, Pennsylvania, Forenede Stater
        • Research Site
      • Lock Haven, Pennsylvania, Forenede Stater
        • Research Site
      • McMurry, Pennsylvania, Forenede Stater
        • Research Site
      • Melrose Park, Pennsylvania, Forenede Stater
        • Research Site
      • Norristown, Pennsylvania, Forenede Stater
        • Research Site
      • Philadelphia, Pennsylvania, Forenede Stater
        • Research Site
      • Pittsburgh, Pennsylvania, Forenede Stater
        • Research Site
      • Plymouth Meeting, Pennsylvania, Forenede Stater
        • Research Site
      • Reading, Pennsylvania, Forenede Stater
        • Research Site
      • Scotland, Pennsylvania, Forenede Stater
        • Research Site
      • Sellersville, Pennsylvania, Forenede Stater
        • Research Site
      • Souderton, Pennsylvania, Forenede Stater
        • Research Site
      • Springfield, Pennsylvania, Forenede Stater
        • Research Site
      • State College, Pennsylvania, Forenede Stater
        • Research Site
      • Stoneboro, Pennsylvania, Forenede Stater
        • Research Site
      • Tipton, Pennsylvania, Forenede Stater
        • Research Site
      • Uniontown, Pennsylvania, Forenede Stater
        • Research Site
      • Upland, Pennsylvania, Forenede Stater
        • Research Site
      • Wallingford, Pennsylvania, Forenede Stater
        • Research Site
      • Warminster, Pennsylvania, Forenede Stater
        • Research Site
      • West Grove, Pennsylvania, Forenede Stater
        • Research Site
      • West Reading, Pennsylvania, Forenede Stater
        • Research Site
      • Wilkes-barre, Pennsylvania, Forenede Stater
        • Research Site
      • York, Pennsylvania, Forenede Stater
        • Research Site
    • Rhode Island
      • Cranston, Rhode Island, Forenede Stater
        • Research Site
      • Johnston, Rhode Island, Forenede Stater
        • Research Site
      • Pawtucket, Rhode Island, Forenede Stater
        • Research Site
      • Providence, Rhode Island, Forenede Stater
        • Research Site
    • South Carolina
      • Charleston, South Carolina, Forenede Stater
        • Research Site
      • Greenville, South Carolina, Forenede Stater
        • Research Site
      • Greer, South Carolina, Forenede Stater
        • Research Site
      • Hampton, South Carolina, Forenede Stater
        • Research Site
      • Moncks Corner, South Carolina, Forenede Stater
        • Research Site
      • Mt Pleasant, South Carolina, Forenede Stater
        • Research Site
      • Orangeburg, South Carolina, Forenede Stater
        • Research Site
      • Simpsonville, South Carolina, Forenede Stater
        • Research Site
    • South Dakota
      • Sioux Falls, South Dakota, Forenede Stater
        • Research Site
    • Tennessee
      • Bristol, Tennessee, Forenede Stater
        • Research Site
      • Chattanooga, Tennessee, Forenede Stater
        • Research Site
      • Clarksville, Tennessee, Forenede Stater
        • Research Site
      • Fayetteville, Tennessee, Forenede Stater
        • Research Site
      • Germantown, Tennessee, Forenede Stater
        • Research Site
      • Hendersonville, Tennessee, Forenede Stater
        • Research Site
      • Jefferson City, Tennessee, Forenede Stater
        • Research Site
      • Johnson City, Tennessee, Forenede Stater
        • Research Site
      • Memphis, Tennessee, Forenede Stater
        • Research Site
      • Morristown, Tennessee, Forenede Stater
        • Research Site
      • Nashville, Tennessee, Forenede Stater
        • Research Site
    • Texas
      • Arlington, Texas, Forenede Stater
        • Research Site
      • Austin, Texas, Forenede Stater
        • Research Site
      • Carrollton, Texas, Forenede Stater
        • Research Site
      • Colleyville, Texas, Forenede Stater
        • Research Site
      • Corpus Christi, Texas, Forenede Stater
        • Research Site
      • Dallas, Texas, Forenede Stater
        • Research Site
      • El Paso, Texas, Forenede Stater
        • Research Site
      • Fort Worth, Texas, Forenede Stater
        • Research Site
      • Friendswood, Texas, Forenede Stater
        • Research Site
      • Ft Worth, Texas, Forenede Stater
        • Research Site
      • Grapevine, Texas, Forenede Stater
        • Research Site
      • Houston, Texas, Forenede Stater
        • Research Site
      • Irving, Texas, Forenede Stater
        • Research Site
      • Lake Jackson, Texas, Forenede Stater
        • Research Site
      • Lubbock, Texas, Forenede Stater
        • Research Site
      • N Richland Hills, Texas, Forenede Stater
        • Research Site
      • New Braunfels, Texas, Forenede Stater
        • Research Site
      • Pharr, Texas, Forenede Stater
        • Research Site
      • Plano, Texas, Forenede Stater
        • Research Site
      • San Antonio, Texas, Forenede Stater
        • Research Site
      • Seguin, Texas, Forenede Stater
        • Research Site
      • Sugar Land, Texas, Forenede Stater
        • Research Site
      • The Woodlands, Texas, Forenede Stater
        • Research Site
      • Tyler, Texas, Forenede Stater
        • Research Site
    • Utah
      • Bountiful, Utah, Forenede Stater
        • Research Site
      • Nephi, Utah, Forenede Stater
        • Research Site
      • Salt Lake City, Utah, Forenede Stater
        • Research Site
    • Vermont
      • Burlington, Vermont, Forenede Stater
        • Research Site
    • Virginia
      • Alexandria, Virginia, Forenede Stater
        • Research Site
      • Arlington, Virginia, Forenede Stater
        • Research Site
      • Burke, Virginia, Forenede Stater
        • Research Site
      • Charlottesville, Virginia, Forenede Stater
        • Research Site
      • Hampton, Virginia, Forenede Stater
        • Research Site
      • Hayes, Virginia, Forenede Stater
        • Research Site
      • Norfolk, Virginia, Forenede Stater
        • Research Site
      • Quinton, Virginia, Forenede Stater
        • Research Site
      • Richmond, Virginia, Forenede Stater
        • Research Site
      • Springfield, Virginia, Forenede Stater
        • Research Site
      • Stuart, Virginia, Forenede Stater
        • Research Site
      • Suffolk, Virginia, Forenede Stater
        • Research Site
      • Weber City, Virginia, Forenede Stater
        • Research Site
      • Yorktown, Virginia, Forenede Stater
        • Research Site
    • Washington
      • Burien, Washington, Forenede Stater
        • Research Site
      • Everett, Washington, Forenede Stater
        • Research Site
      • Gig Harbor, Washington, Forenede Stater
        • Research Site
      • Olympia, Washington, Forenede Stater
        • Research Site
      • Seattle, Washington, Forenede Stater
        • Research Site
      • Spokane, Washington, Forenede Stater
        • Research Site
      • Wenatchee, Washington, Forenede Stater
        • Research Site
    • West Virginia
      • Charleston, West Virginia, Forenede Stater
        • Research Site
      • Lewisburg, West Virginia, Forenede Stater
        • Research Site
    • Wisconsin
      • Beloit, Wisconsin, Forenede Stater
        • Research Site
      • Green Bay, Wisconsin, Forenede Stater
        • Research Site
      • Madison, Wisconsin, Forenede Stater
        • Research Site
      • Menomonee Falls, Wisconsin, Forenede Stater
        • Research Site
      • Milwaukee, Wisconsin, Forenede Stater
        • Research Site
  • Holland
      • Alkmaar, Holland
        • Research Site
      • Amersfoort, Holland
        • Research Site
      • Amsterdam, Holland
        • Research Site
      • Breda, Holland
        • Research Site
      • Den Haag, Holland
        • Research Site
      • Deventer, Holland
        • Research Site
      • Eindhoven, Holland
        • Research Site
      • Gouda, Holland
        • Research Site
      • Groningen, Holland
        • Research Site
      • Hoorn, Holland
        • Research Site
      • Leiden, Holland
        • Research Site
      • Nijmegen, Holland
        • Research Site
      • Rotterdam, Holland
        • Research Site
      • Tilburg, Holland
        • Research Site
      • Utrecht, Holland
        • Research Site
      • Velp, Holland
        • Research Site
      • Zoetermeer, Holland
        • Research Site
  • Israel
      • Ashkelon Shore, Israel
        • Research Site
      • Beer Yakov, Israel
        • Research Site
      • Haifa, Israel
        • Research Site
      • Holon, Israel
        • Research Site
      • Jerusalem, Israel
        • Research Site
      • Kfar-saba, Israel
        • Research Site
      • Safed, Israel
        • Research Site
      • Tel Aviv, Israel
        • Research Site
      • Tel-hashomer, Israel
        • Research Site
      • Zrifin, Israel
        • Research Site
    • Jerusalem
      • Kiryat Hadassah, Jerusalem, Israel
        • Research Site
  • Mexico
      • Aguascalientes, Mexico
        • Research Site
    • D.F
      • Mexico City, D.F, Mexico
        • Research Site
    • Jalisco
      • Guadalajara, Jalisco, Mexico
        • Research Site
    • Nuevo Leon
      • Monterrey, Nuevo Leon, Mexico
        • Research Site
    • SLP
      • San Luis Potosi, SLP, Mexico
        • Research Site
    • Sinaloa
      • Culiacan, Sinaloa, Mexico
        • Research Site
  • Norge
      • Bekkestua, Norge
        • Research Site
      • Bergen, Norge
        • Research Site
      • Boverbru, Norge
        • Research Site
      • Elverum, Norge
        • Research Site
      • Flatasen, Norge
        • Research Site
      • Fredrikstad, Norge
        • Research Site
      • Halden, Norge
        • Research Site
      • Heimdal, Norge
        • Research Site
      • Kristiansand, Norge
        • Research Site
      • Laksevag, Norge
        • Research Site
      • Lena, Norge
        • Research Site
      • Lierskogen, Norge
        • Research Site
      • Lovenstad, Norge
        • Research Site
      • Lysaker, Norge
        • Research Site
      • Moelv, Norge
        • Research Site
      • Moss, Norge
        • Research Site
      • Oslo, Norge
        • Research Site
      • Osteras, Norge
        • Research Site
      • Paradis, Norge
        • Research Site
      • Radal, Norge
        • Research Site
      • Randaberg, Norge
        • Research Site
      • SKI, Norge
        • Research Site
      • Skedsmokorset, Norge
        • Research Site
      • Skiptvet, Norge
        • Research Site
      • Snaroya, Norge
        • Research Site
      • Sogndal, Norge
        • Research Site
      • Spikkestad, Norge
        • Research Site
      • Stavanger, Norge
        • Research Site
      • Strommen, Norge
        • Research Site
      • Svelvik, Norge
        • Research Site
      • Trollasen, Norge
        • Research Site
      • Trondheim, Norge
        • Research Site
  • Panama
      • Panama, Panama
        • Research Site
  • Polen
      • Aleksandrow Lodzki, Polen
        • Research Site
      • Bydgoszcz, Polen
        • Research Site
      • Bytom, Polen
        • Research Site
      • Chodziez, Polen
        • Research Site
      • Chorzow, Polen
        • Research Site
      • Gdansk, Polen
        • Research Site
      • Gliwice, Polen
        • Research Site
      • Jelcz-laskowice, Polen
        • Research Site
      • Karpacz, Polen
        • Research Site
      • Katowice, Polen
        • Research Site
      • Koluszki, Polen
        • Research Site
      • Krakow, Polen
        • Research Site
      • Linia, Polen
        • Research Site
      • Lodz, Polen
        • Research Site
      • Lublin, Polen
        • Research Site
      • Nowogard, Polen
        • Research Site
      • Olawa, Polen
        • Research Site
      • Olsztyn, Polen
        • Research Site
      • Opalenica, Polen
        • Research Site
      • Opole, Polen
        • Research Site
      • Ostrow Wielkopolski, Polen
        • Research Site
      • Piekary Slaskie, Polen
        • Research Site
      • Poznan, Polen
        • Research Site
      • Pulawy, Polen
        • Research Site
      • Radom, Polen
        • Research Site
      • Radziejow, Polen
        • Research Site
      • Rybnik, Polen
        • Research Site
      • Sieradz, Polen
        • Research Site
      • Skierniewice, Polen
        • Research Site
      • Slupca, Polen
        • Research Site
      • Sobotka, Polen
        • Research Site
      • Sopot, Polen
        • Research Site
      • Szczecin, Polen
        • Research Site
      • Tarnow, Polen
        • Research Site
      • Torun, Polen
        • Research Site
      • Trzcianka, Polen
        • Research Site
      • Turek, Polen
        • Research Site
      • Wabrzezno, Polen
        • Research Site
      • Warszawa, Polen
        • Research Site
      • Wejherowo, Polen
        • Research Site
      • Wroclaw, Polen
        • Research Site
      • Zabrze, Polen
        • Research Site
  • Puerto Rico
      • Aguas Buenas, Puerto Rico
        • Research Site
      • Caguas, Puerto Rico
        • Research Site
      • Cidra, Puerto Rico
        • Research Site
      • Levittown-toa Baja, Puerto Rico
        • Research Site
      • Ponce, Puerto Rico
        • Research Site
      • San Juan, Puerto Rico
        • Research Site
  • Rumænien
      • Brasov, Rumænien
        • Research Site
      • Bucharest, Rumænien
        • Research Site
      • Bucuresti, Rumænien
        • Research Site
    • Cluj
      • Cluj Napoca, Cluj, Rumænien
        • Research Site
    • Timis
      • Timisoara, Timis, Rumænien
        • Research Site
  • Schweiz
    • Schweiz
      • Olten, Schweiz, Schweiz
        • Research Site
  • Sydafrika
      • Benoni, Sydafrika
        • Research Site
      • Halfway House, Sydafrika
        • Research Site
      • Johannesburg, Sydafrika
        • Research Site
      • Lakeview, Retreat, Sydafrika
        • Research Site
      • Rustenburg, Sydafrika
        • Research Site
      • Somerset West, Sydafrika
        • Research Site
      • Vanderbijlpark, Sydafrika
        • Research Site
      • Worcester, Sydafrika
        • Research Site
    • Cape Province
      • Claremont, Cape Province, Sydafrika
        • Research Site
    • Cape Town
      • Athlone, Cape Town, Sydafrika
        • Research Site
    • Gauteng
      • Florida Park, Gauteng, Sydafrika
        • Research Site
      • Lenasia, Gauteng, Sydafrika
        • Research Site
      • Pretoria, Gauteng, Sydafrika
        • Research Site
      • Witbank, Gauteng, Sydafrika
        • Research Site
    • Kwazulu Natal
      • Durban, Kwazulu Natal, Sydafrika
        • Research Site
      • Umkomaas, Kwazulu Natal, Sydafrika
        • Research Site
    • Morningside
      • Morningside Manor, Morningside, Sydafrika
        • Research Site
    • Port Elizabeth
      • Korsten, Port Elizabeth, Sydafrika
        • Research Site
    • Pretoria
      • Hillcrest, Pretoria, Sydafrika
        • Research Site
  • Tyskland
      • Berlin, Tyskland
        • Research Site
      • Bochum, Tyskland
        • Research Site
      • Chemnitz, Tyskland
        • Research Site
      • Dortmund, Tyskland
        • Research Site
      • Dresden, Tyskland
        • Research Site
      • Frankfurt, Tyskland
        • Research Site
      • Gorlitz, Tyskland
        • Research Site
      • Hamburg, Tyskland
        • Research Site
      • Kunzing, Tyskland
        • Research Site
      • Leipzig, Tyskland
        • Research Site
      • Magdeburg, Tyskland
        • Research Site
      • Nurnberg, Tyskland
        • Research Site
      • ULM, Tyskland
        • Research Site
      • Witten, Tyskland
        • Research Site
  • Uruguay
      • Montevideo, Uruguay
        • Research Site
  • Venezuela
      • Caracas, Venezuela
        • Research Site
      • Punto Fijo, Estado Falcon, Venezuela
        • Research Site
    • Estado Aragua
      • Maracay, Municipio Girardot, Estado Aragua, Venezuela
        • Research Site
    • Estado Barinas
      • Barinas, Estado Barinas, Venezuela
        • Research Site
    • Estado Bolivar
      • Ciudad Bolivar, Estado Bolivar, Venezuela
        • Research Site
      • Puerto Ordaz, Estado Bolivar, Venezuela
        • Research Site
    • Estado Carabobo
      • Valencia, Estado Carabobo, Venezuela
        • Research Site
    • Estado Lara
      • Barquisimeto, Estado Lara, Venezuela
        • Research Site
    • Estado Merida
      • Merida, Estado Merida, Venezuela
        • Research Site
    • Estado Nueva Esparta
      • Porlamar, Estado Nueva Esparta, Venezuela
        • Research Site
    • Estado Zulia
      • Maracaibo, Estado Zulia, Venezuela
        • Research Site
    • Municipio Baruta
      • Latrinidad Caracas, Municipio Baruta, Venezuela
        • Research Site

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

50 år og ældre (VOKSEN, OLDER_ADULT)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inklusionskriterier:

  • Mænd 50 år eller ældre, kvinder 60 år eller ældre
  • Lave til normale niveauer af low density lipoprotein (LDL) kolesterol (< 130mg/dL)
  • Forhøjede niveauer af C-reaktivt protein (CRP) > 2,0 mg/L

Ekskluderingskriterier:

  • Anamnese med kardiovaskulære eller cerebrovaskulære hændelser
  • Aktiv leversygdom
  • Diabetes mellitus
  • Ukontrolleret hypertension eller hypothyroidisme
  • Historie om visse maligniteter
  • Kroniske betændelsestilstande
  • Historie om alkohol- eller stofmisbrug

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: FOREBYGGELSE
  • Tildeling: TILFÆLDIGT
  • Interventionel model: PARALLEL
  • Maskning: FIDOBELT

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
PLACEBO_COMPARATOR: Placebo
Placebo én gang dagligt
Andet: Placebo
Mundtlig
EKSPERIMENTEL: Rosuvastatin
Rosuvastatin 20 mg én gang dagligt
Medicin: Rosuvastatin
Mundtlig
Andre navne:
  • Crestor

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Tid til større hjertehændelse (kardiovaskulær død, slagtilfælde, myokardieinfarkt, hospitalsindlæggelse på grund af ustabil angina eller arteriel revaskularisering)
Tidsramme: op til 5 år
Dage fra randomisering til den første af CV-død, slagtilfælde, MI, hospitalsindlæggelse for ustabil angina eller arteriel revaskularisering. Hvis der ikke sker nogen begivenhed, sker censur tidligst af ophørsdatoen eller virkningsdatoen den 30. marts 2008. Begivenheder blev bedømt af et endpoint-udvalg. Kaplan-Meier estimat af middelværdien
op til 5 år

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Tid til død på grund af enhver årsag
Tidsramme: op til 5 år
Dage fra randomisering til død. Hvis der ikke er dødsfald, finder censur sted tidligst af ophørsdatoen eller virkningsgrænsen den 30. marts 2008. Kaplan-Meier estimat af middelværdien
op til 5 år
Tid til ikke-kardiovaskulær død
Tidsramme: op til 5 år
Dage fra randomisering til død af en ikke-kardiovaskulær årsag. Hvis der ikke er nogen begivenhed, finder censur sted tidligst af ophørsdatoen eller virkningsgrænsen den 30. marts 2008. Begivenheder blev bedømt af et endpoint-udvalg. Kaplan-Meier estimat af middelværdien
op til 5 år
Tid til udvikling af diabetes mellitus
Tidsramme: op til 5 år
Dage fra randomisering til udvikling af diabetes. Hvis der ikke blev udviklet diabetes, fandt censur sted på ophørsdatoen. Kaplan-Meier estimat af middelværdien
op til 5 år
Tid til venøs tromboembolisk hændelse
Tidsramme: op til 5 år
Tid fra randomisering til den første venøse tromboemboliske hændelse. Kaplan-Meier estimat af middelværdien
op til 5 år
Tid til knoglebrud
Tidsramme: Op til 5 år
Dage fra randomisering til knoglebrud. Hvis der ikke er nogen begivenhed, finder censur sted tidligst af ophørsdatoen eller virkningsgrænsen den 30. marts 2008. Kaplan-Meier estimat af middelværdien
Op til 5 år

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

AstraZeneca

Efterforskere

  • Studieleder: Judith Hsia, MD, AstraZeneca
  • Studiestol: Paul Ridker, MD, Brigham and Women's Hospital

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Hjælpsomme links

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

1. februar 2003

Primær færdiggørelse (FAKTISKE)

1. september 2008

Studieafslutning (FAKTISKE)

1. september 2008

Datoer for studieregistrering

Først indsendt

13. oktober 2005

Først indsendt, der opfyldte QC-kriterier

13. oktober 2005

Først opslået (SKØN)

17. oktober 2005

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (SKØN)

24. marts 2014

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

6. februar 2014

Sidst verificeret

1. februar 2014

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • D3560L00030
  • Jupiter
  • 4522US/0011

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Forhøjet højfølsomt C-reaktivt protein (hsCRP)

Kliniske forsøg med Placebo

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Malta

Betingelser

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Sponsor / samarbejdspartnere

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