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Kemoterapi med eller uden Bevacizumab til behandling af patienter med trin IB, trin II eller trin IIIA Ikke-småcellet lungekræft, der blev fjernet ved kirurgi

16. april 2024 opdateret af: National Cancer Institute (NCI)

Et fase III randomiseret forsøg med adjuverende kemoterapi med eller uden Bevacizumab til patienter med fuldstændigt resekeret stadium IB (≥ 4 cm) - IIIA ikke-småcellet lungekræft (NSCLC)

Dette randomiserede fase III-forsøg undersøger kemoterapi og bevacizumab for at se, hvor godt de virker sammenlignet med kemoterapi alene ved behandling af patienter med stadium IB, stadium II eller stadium IIIA ikke-småcellet lungekræft, som blev fjernet ved kirurgi. Lægemidler, der bruges i kemoterapi, virker på forskellige måder for at stoppe væksten af tumorceller, enten ved at dræbe cellerne, ved at stoppe dem i at dele sig eller ved at stoppe dem i at sprede sig. At give mere end ét lægemiddel (kombinationskemoterapi) kan dræbe flere tumorceller. Monoklonale antistoffer, såsom bevacizumab, kan interferere med tumorcellernes evne til at vokse og sprede sig. Bevacizumab kan også stoppe væksten af ikke-småcellet lungekræft ved at blokere væksten af nye blodkar, der er nødvendige for tumorvækst. Det vides endnu ikke, om kemoterapi er mere effektiv med eller uden bevacizumab til behandling af ikke-småcellet lungekræft.

Studieoversigt

Status

Aktiv, ikke rekrutterende

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

PRIMÆRE MÅL:

I. At evaluere den samlede overlevelse med kemoterapi med eller uden bevacizumab anvendt i adjuverende omgivelser hos patienter med resekeret stadium IB (>= 4 cm) - IIIA ikke-småcellet lungecancer (NSCLC).

SEKUNDÆRE MÅL:

I. At evaluere sygdomsfri overlevelse og toksicitet med kemoterapi med eller uden bevacizumab anvendt i adjuverende omgivelser hos patienter med resekeret stadium IB (>= 4 cm) - IIIA NSCLC.

SAMMENLIGNENDE MÅL:

I. At udføre analyser af væv og blod for at etablere faktorer, der forudsiger klinisk udfald hos patienter, der får kemoterapi, med eller uden bevacizumab, for resekeret tidligt stadium af NSCLC.

II. For at bestemme, om rygestatus er forbundet med udfaldet for patienter med resekeret stadium IB (>= 4 cm) - IIIA NSCLC behandlet med kemoterapi med eller uden bevacizumab i adjuverende omgivelser.

OVERSIGT: Patienterne randomiseres til 1 ud af 2 behandlingsarme.

ARM I (adjuverende kemoterapi uden bevacizumab): Patienterne får 1 ud af 4 kemoterapiregimer.

REGIMEN 1: Patienterne får vinorelbin-ditartrat intravenøst (IV) over 10 minutter på dag 1 og 8 og cisplatin IV over 60 minutter på dag 1 umiddelbart efter indgivelse af vinorelbin-ditartrat.

REGIMEN 2: Patienterne får docetaxel IV over 1 time på dag 1 og cisplatin over 1 time på dag 1 umiddelbart efter administration af docetaxel.

REGIMEN 3: Patienterne får gemcitabinhydrochlorid IV over 30 minutter på dag 1 og 8 og cisplatin IV over 60 minutter på dag 1 umiddelbart efter administration af gemcitabin.

REGIMEN 4 (kun ikke-pladeepitel histologi): Patienterne får pemetrexed dinatrium IV over 10 minutter og cisplatin IV over 1 time på dag 1 umiddelbart efter administration af pemetrexed dinatrium.

I alle regimer gentages behandlingen hver 21. dag i op til 4 kure i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II (adjuverende kemoterapi med bevacizumab): Patienterne får kemoterapi som i arm I. Patienterne får også bevacizumab IV over 30-90 minutter på dag 1. Behandling med bevacizumab gentages hver 21. dag i op til 1 år.

Efter afsluttet undersøgelsesbehandling følges patienterne periodisk i 10 år.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

1501

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Canada
- Alberta
  - Edmonton, Alberta, Canada, T6G 1Z2
    - Cross Cancer Institute
- British Columbia
  - Vancouver, British Columbia, Canada, V5Z 4E6
    - BCCA-Vancouver Cancer Centre
- Manitoba
  - Winnipeg, Manitoba, Canada, R3E 0V9
    - CancerCare Manitoba
- New Brunswick
  - Moncton, New Brunswick, Canada, E1C 6Z8
    - The Moncton Hospital
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3H 2Y9
    - QEII Health Sciences Centre/Nova Scotia Health Authority
- Ontario
  - Barrie, Ontario, Canada, L4M 6M2
    - Royal Victoria Regional Health Centre
  - London, Ontario, Canada, N6A 4L6
    - London Regional Cancer Program
  - Mississauga, Ontario, Canada, L5B 1B8
    - Trillium Health Partners - Mississauga Hospital
  - Ottawa, Ontario, Canada, K1H 8L6
    - Ottawa Hospital and Cancer Center-General Campus
  - Sault Ste Marie, Ontario, Canada, P6B 0A8
    - Algoma District Cancer Program Sault Area Hospital
  - Sudbury, Ontario, Canada, P3E 5J1
    - Health Sciences North
  - Thunder Bay, Ontario, Canada, P7B 6V4
    - Thunder Bay Regional Health Science Centre
  - Toronto, Ontario, Canada, M5G 2M9
    - University Health Network-Princess Margaret Hospital
  - Toronto, Ontario, Canada, M9C 1A5
    - Trillium Health Partners - Queensway Health Centre
- Quebec
  - Greenfield Park, Quebec, Canada, J4V 2H1
    - CSSS Champlain-Charles Le Moyne
  - Montreal, Quebec, Canada, H2W 1S6
    - McGill University Department of Oncology
- Saskatchewan
  - Regina, Saskatchewan, Canada, S4T 7T1
    - Allan Blair Cancer Centre
  - Saskatoon, Saskatchewan, Canada, S7N 4H4
    - Saskatoon Cancer Centre
Forenede Stater
- Alabama
  - Anniston, Alabama, Forenede Stater, 36202
    - Northeast Alabama Regional Medical Center
  - Huntsville, Alabama, Forenede Stater, 35805
    - Clearview Cancer Institute
  - Mobile, Alabama, Forenede Stater, 36688
    - University of South Alabama Mitchell Cancer Institute
  - Mobile, Alabama, Forenede Stater, 36608
    - Providence Hospital
- Alaska
  - Anchorage, Alaska, Forenede Stater, 99508
    - Providence Alaska Medical Center
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Regional Hospital
- Arizona
  - Scottsdale, Arizona, Forenede Stater, 85259
    - Mayo Clinic in Arizona
  - Tucson, Arizona, Forenede Stater, 85704
    - University of Arizona Cancer Center-Orange Grove Campus
  - Tucson, Arizona, Forenede Stater, 85719
    - Banner University Medical Center - Tucson
  - Tucson, Arizona, Forenede Stater, 85719
    - University of Arizona Cancer Center-North Campus
- Arkansas
  - Fort Smith, Arkansas, Forenede Stater, 72903
    - Mercy Hospital Fort Smith
  - Jonesboro, Arkansas, Forenede Stater, 72401
    - NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
  - Jonesboro, Arkansas, Forenede Stater, 72401
    - NEA Baptist Memorial Hospital
  - Jonesboro, Arkansas, Forenede Stater, 72401
    - Saint Bernards Regional Medical Center
  - Little Rock, Arkansas, Forenede Stater, 72205
    - University of Arkansas for Medical Sciences
  - Little Rock, Arkansas, Forenede Stater, 72205
    - John L McClellan Memorial Veterans Hospital
- California
  - Anaheim, California, Forenede Stater, 92806
    - Kaiser Permanente-Anaheim
  - Antioch, California, Forenede Stater, 94531
    - Kaiser Permanente-Deer Valley Medical Center
  - Arroyo Grande, California, Forenede Stater, 93420
    - PCR Oncology
  - Baldwin Park, California, Forenede Stater, 91706
    - Kaiser Permanente-Baldwin Park
  - Bellflower, California, Forenede Stater, 90706
    - Kaiser Permanente-Bellflower
  - Berkeley, California, Forenede Stater, 94704
    - Alta Bates Summit Medical Center-Herrick Campus
  - Burbank, California, Forenede Stater, 91505
    - Providence Saint Joseph Medical Center/Disney Family Cancer Center
  - Burlingame, California, Forenede Stater, 94010
    - Mills-Peninsula Medical Center
  - Castro Valley, California, Forenede Stater, 94546
    - Eden Hospital Medical Center
  - Castro Valley, California, Forenede Stater, 94546
    - East Bay Radiation Oncology Center
  - Castro Valley, California, Forenede Stater, 94546
    - Valley Medical Oncology Consultants-Castro Valley
  - Chico, California, Forenede Stater, 95973
    - Adventist Health Cancer Care Center Chico
  - Clovis, California, Forenede Stater, 93611
    - Community Cancer Institute
  - Duarte, California, Forenede Stater, 91010
    - City of Hope Comprehensive Cancer Center
  - Emeryville, California, Forenede Stater, 94608
    - Bay Area Breast Surgeons Inc
  - Emeryville, California, Forenede Stater, 94608
    - Epic Care Partners in Cancer Care
  - Fontana, California, Forenede Stater, 92335
    - Kaiser Permanente-Fontana
  - Fremont, California, Forenede Stater, 94538
    - Kaiser Permanente-Fremont
  - Fremont, California, Forenede Stater, 94538
    - Valley Medical Oncology Consultants-Fremont
  - Fresno, California, Forenede Stater, 93720
    - Kaiser Permanente-Fresno
  - Fresno, California, Forenede Stater, 93720
    - California Cancer Associates for Research and Excellence (cCare)
  - Fullerton, California, Forenede Stater, 92835
    - Saint Jude Medical Center
  - Glendale, California, Forenede Stater, 91204
    - Glendale Memorial Hospital and Health Center
  - Greenbrae, California, Forenede Stater, 94904
    - Marin Cancer Care Inc
  - Greenbrae, California, Forenede Stater, 94904
    - Marin General Hospital
  - Harbor City, California, Forenede Stater, 90710
    - Kaiser Permanente - Harbor City
  - Hayward, California, Forenede Stater, 94545
    - Saint Rose Hospital
  - Irvine, California, Forenede Stater, 92618
    - Kaiser Permanente-Irvine
  - Loma Linda, California, Forenede Stater, 92354
    - Loma Linda University Medical Center
  - Long Beach, California, Forenede Stater, 90806
    - Long Beach Memorial Medical Center-Todd Cancer Institute
  - Los Angeles, California, Forenede Stater, 90033
    - USC / Norris Comprehensive Cancer Center
  - Los Angeles, California, Forenede Stater, 90027
    - Kaiser Permanente Los Angeles Medical Center
  - Los Angeles, California, Forenede Stater, 90034
    - Kaiser Permanente West Los Angeles
  - Los Angeles, California, Forenede Stater, 90033
    - Los Angeles General Medical Center
  - Martinez, California, Forenede Stater, 94553-3156
    - Contra Costa Regional Medical Center
  - Marysville, California, Forenede Stater, 95901
    - Fremont - Rideout Cancer Center
  - Merced, California, Forenede Stater, 95340
    - Mercy UC Davis Cancer Center
  - Modesto, California, Forenede Stater, 95355
    - Memorial Medical Center
  - Modesto, California, Forenede Stater, 95356
    - Kaiser Permanente-Modesto
  - Monterey, California, Forenede Stater, 93940
    - Community Hospital of Monterey Peninsula
  - Mountain View, California, Forenede Stater, 94040
    - El Camino Hospital
  - Mountain View, California, Forenede Stater, 94040
    - Palo Alto Medical Foundation-Camino Division
  - Novato, California, Forenede Stater, 94945
    - Sutter Cancer Research Consortium
  - Oakland, California, Forenede Stater, 94611
    - Kaiser Permanente-Oakland
  - Oakland, California, Forenede Stater, 94611
    - Kaiser Permanente Oakland-Broadway
  - Oakland, California, Forenede Stater, 94609
    - Alta Bates Summit Medical Center - Summit Campus
  - Oakland, California, Forenede Stater, 94609
    - Hematology and Oncology Associates-Oakland
  - Oakland, California, Forenede Stater, 94602
    - Highland General Hospital
  - Oakland, California, Forenede Stater, 94609
    - Tom K Lee Inc
  - Oakland, California, Forenede Stater, 94609
    - Bay Area Tumor Institute
  - Orange, California, Forenede Stater, 92868
    - UC Irvine Health/Chao Family Comprehensive Cancer Center
  - Orange, California, Forenede Stater, 92868
    - Saint Joseph Hospital - Orange
  - Palm Springs, California, Forenede Stater, 92262
    - Desert Regional Medical Center
  - Palo Alto, California, Forenede Stater, 94304
    - Stanford Cancer Institute Palo Alto
  - Palo Alto, California, Forenede Stater, 94301
    - Palo Alto Medical Foundation Health Care
  - Panorama City, California, Forenede Stater, 91402
    - Kaiser Permanente - Panorama City
  - Pleasanton, California, Forenede Stater, 94588
    - Valley Care Health System - Pleasanton
  - Pleasanton, California, Forenede Stater, 94588
    - Valley Medical Oncology Consultants
  - Pomona, California, Forenede Stater, 91767
    - Pomona Valley Hospital Medical Center
  - Rancho Cordova, California, Forenede Stater, 95670
    - Kaiser Permanente-Rancho Cordova Cancer Center
  - Rancho Mirage, California, Forenede Stater, 92270
    - Eisenhower Medical Center
  - Redwood City, California, Forenede Stater, 94063
    - Kaiser Permanente-Redwood City
  - Richmond, California, Forenede Stater, 94801
    - Kaiser Permanente-Richmond
  - Riverside, California, Forenede Stater, 92505
    - Kaiser Permanente-Riverside
  - Rohnert Park, California, Forenede Stater, 94928
    - Rohnert Park Cancer Center
  - Roseville, California, Forenede Stater, 95678
    - The Permanente Medical Group-Roseville Radiation Oncology
  - Roseville, California, Forenede Stater, 95661
    - Kaiser Permanente-Roseville
  - Roseville, California, Forenede Stater, 95661
    - Sutter Roseville Medical Center
  - Sacramento, California, Forenede Stater, 95816
    - Sutter Medical Center Sacramento
  - Sacramento, California, Forenede Stater, 95817
    - University of California Davis Comprehensive Cancer Center
  - Sacramento, California, Forenede Stater, 95823
    - Kaiser Permanente-South Sacramento
  - Sacramento, California, Forenede Stater, 95823
    - South Sacramento Cancer Center
  - Sacramento, California, Forenede Stater, 95825
    - Kaiser Permanente - Sacramento
  - Sacramento, California, Forenede Stater, 95819
    - Mercy General Hospital
  - Saint Helena, California, Forenede Stater, 94574
    - Saint Helena Hospital
  - Salinas, California, Forenede Stater, 93901
    - Salinas Valley Memorial
  - San Diego, California, Forenede Stater, 92120
    - Kaiser Permanente-San Diego Zion
  - San Diego, California, Forenede Stater, 92108
    - Kaiser Permanente-San Diego Mission
  - San Francisco, California, Forenede Stater, 94115
    - Kaiser Permanente-San Francisco
  - San Francisco, California, Forenede Stater, 94115
    - California Pacific Medical Center-Pacific Campus
  - San Francisco, California, Forenede Stater, 94115
    - UCSF Medical Center-Mount Zion
  - San Francisco, California, Forenede Stater, 94110
    - Zuckerberg San Francisco General Hospital
  - San Jose, California, Forenede Stater, 95119
    - Kaiser Permanente-Santa Teresa-San Jose
  - San Leandro, California, Forenede Stater, 94577
    - Kaiser Permanente San Leandro
  - San Marcos, California, Forenede Stater, 92078
    - Kaiser Permanente-San Marcos
  - San Pablo, California, Forenede Stater, 94806
    - Doctors Medical Center- JC Robinson Regional Cancer Center
  - San Rafael, California, Forenede Stater, 94903
    - Kaiser Permanente-San Rafael
  - Santa Clara, California, Forenede Stater, 95051
    - Kaiser Permanente Medical Center - Santa Clara
  - Santa Rosa, California, Forenede Stater, 95403
    - Kaiser Permanente-Santa Rosa
  - Santa Rosa, California, Forenede Stater, 95403
    - Sutter Pacific Medical Foundation
  - Santa Rosa, California, Forenede Stater, 95405
    - Providence Santa Rosa Memorial Hospital
  - South San Francisco, California, Forenede Stater, 94080
    - Kaiser Permanente Cancer Treatment Center
  - South San Francisco, California, Forenede Stater, 94080
    - Kaiser Permanente-South San Francisco
  - Stockton, California, Forenede Stater, 95210
    - Kaiser Permanente-Stockton
  - Sunnyvale, California, Forenede Stater, 94086
    - Palo Alto Medical Foundation-Sunnyvale
  - Truckee, California, Forenede Stater, 96161
    - Gene Upshaw Memorial Tahoe Forest Cancer Center
  - Vacaville, California, Forenede Stater, 95688
    - Kaiser Permanente Medical Center-Vacaville
  - Vacaville, California, Forenede Stater, 95687
    - Northbay Cancer Center
  - Vallejo, California, Forenede Stater, 94589
    - Kaiser Permanente-Vallejo
  - Vallejo, California, Forenede Stater, 94589
    - Sutter Solano Medical Center/Cancer Center
  - Walnut Creek, California, Forenede Stater, 94596
    - Kaiser Permanente-Walnut Creek
  - Woodland Hills, California, Forenede Stater, 91367
    - Kaiser Permanente-Woodland Hills
- Colorado
  - Alamosa, Colorado, Forenede Stater, 81101
    - San Luis Valley Regional Medical Center
  - Aurora, Colorado, Forenede Stater, 80012
    - The Medical Center of Aurora
  - Aurora, Colorado, Forenede Stater, 80045
    - Rocky Mountain Regional VA Medical Center
  - Aurora, Colorado, Forenede Stater, 80045
    - UCHealth University of Colorado Hospital
  - Boulder, Colorado, Forenede Stater, 80301
    - Boulder Community Hospital
  - Colorado Springs, Colorado, Forenede Stater, 80907
    - Penrose-Saint Francis Healthcare
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - UCHealth Memorial Hospital Central
  - Denver, Colorado, Forenede Stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forenede Stater, 80217-3364
    - University of Colorado
  - Denver, Colorado, Forenede Stater, 80205
    - Kaiser Permanente-Franklin
  - Denver, Colorado, Forenede Stater, 80218
    - Presbyterian - Saint Lukes Medical Center - Health One
  - Denver, Colorado, Forenede Stater, 80218
    - SCL Health Saint Joseph Hospital
  - Denver, Colorado, Forenede Stater, 80220
    - Rose Medical Center
  - Denver, Colorado, Forenede Stater, 80204
    - Denver Health Medical Center
  - Denver, Colorado, Forenede Stater, 80222
    - Western States Cancer Research NCORP
  - Edwards, Colorado, Forenede Stater, 81632
    - Shaw Cancer Center
  - Englewood, Colorado, Forenede Stater, 80113
    - Swedish Medical Center
  - Fort Collins, Colorado, Forenede Stater, 80524
    - Poudre Valley Hospital
  - Glenwood Springs, Colorado, Forenede Stater, 81601
    - Valley View Hospital Cancer Center
  - Grand Junction, Colorado, Forenede Stater, 81501
    - Saint Mary's Hospital and Regional Medical Center
  - Greeley, Colorado, Forenede Stater, 80631
    - North Colorado Medical Center
  - Lafayette, Colorado, Forenede Stater, 80026
    - Kaiser Permanente-Rock Creek
  - Lakewood, Colorado, Forenede Stater, 80228
    - Saint Anthony Hospital
  - Littleton, Colorado, Forenede Stater, 80122
    - Littleton Adventist Hospital
  - Lone Tree, Colorado, Forenede Stater, 80124
    - Sky Ridge Medical Center
  - Longmont, Colorado, Forenede Stater, 80501
    - Longmont United Hospital
  - Loveland, Colorado, Forenede Stater, 80539
    - McKee Medical Center
  - Montrose, Colorado, Forenede Stater, 81401
    - Montrose Memorial Hospital
  - Parker, Colorado, Forenede Stater, 80138
    - Parker Adventist Hospital
  - Pueblo, Colorado, Forenede Stater, 81004
    - Saint Mary Corwin Medical Center
  - Thornton, Colorado, Forenede Stater, 80229
    - North Suburban Medical Center
  - Wheat Ridge, Colorado, Forenede Stater, 80033
    - SCL Health Lutheran Medical Center
- Connecticut
  - Bridgeport, Connecticut, Forenede Stater, 06610
    - Bridgeport Hospital
  - Bridgeport, Connecticut, Forenede Stater, 06606
    - Hartford HealthCare - Saint Vincent's Medical Center
  - Greenwich, Connecticut, Forenede Stater, 06830
    - Greenwich Hospital
  - Hartford, Connecticut, Forenede Stater, 06105
    - Smilow Cancer Hospital Care Center at Saint Francis
  - Hartford, Connecticut, Forenede Stater, 06102
    - Hartford Hospital
  - Meriden, Connecticut, Forenede Stater, 06451
    - Midstate Medical Center
  - Middletown, Connecticut, Forenede Stater, 06457
    - Middlesex Hospital
  - New Britain, Connecticut, Forenede Stater, 06050
    - The Hospital of Central Connecticut
  - New Haven, Connecticut, Forenede Stater, 06520
    - Yale University
  - Norwalk, Connecticut, Forenede Stater, 06856
    - Norwalk Hospital
  - Norwich, Connecticut, Forenede Stater, 06360
    - Eastern Connecticut Hematology and Oncology Associates
  - Stamford, Connecticut, Forenede Stater, 06904
    - Stamford Hospital/Bennett Cancer Center
  - Torrington, Connecticut, Forenede Stater, 06790
    - Smilow Cancer Hospital-Torrington Care Center
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Harold Leever Regional Cancer Center
- Delaware
  - Dover, Delaware, Forenede Stater, 19901
    - Bayhealth Hospital Kent Campus
  - Lewes, Delaware, Forenede Stater, 19958
    - Beebe Medical Center
  - Newark, Delaware, Forenede Stater, 19718
    - Christiana Care Health System-Christiana Hospital
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20010
    - MedStar Washington Hospital Center
  - Washington, District of Columbia, Forenede Stater, 20007
    - MedStar Georgetown University Hospital
  - Washington, District of Columbia, Forenede Stater, 20016
    - Sibley Memorial Hospital
  - Washington, District of Columbia, Forenede Stater, 20037
    - George Washington University Medical Center
- Florida
  - Boca Raton, Florida, Forenede Stater, 33486
    - Boca Raton Regional Hospital
  - Boca Raton, Florida, Forenede Stater, 33428
    - Lynn Regional Cancer Center - West
  - Boca Raton, Florida, Forenede Stater, 33486
    - Boca Raton Comprehensive Cancer Center
  - Daytona Beach, Florida, Forenede Stater, 32114
    - Halifax Health Medical Center-Centers for Oncology
  - Daytona Beach, Florida, Forenede Stater, 32117
    - Florida Hospital Memorial Medical Center
  - Fort Lauderdale, Florida, Forenede Stater, 33316
    - Broward Health Medical Center
  - Fort Lauderdale, Florida, Forenede Stater, 33308
    - Holy Cross Hospital
  - Gainesville, Florida, Forenede Stater, 32605
    - Florida Cancer Specialists-Gainesville Cancer Center
  - Hollywood, Florida, Forenede Stater, 33021
    - Memorial Regional Hospital/Joe DiMaggio Children's Hospital
  - Jacksonville, Florida, Forenede Stater, 32207
    - Baptist MD Anderson Cancer Center
  - Jacksonville, Florida, Forenede Stater, 32224-9980
    - Mayo Clinic in Florida
  - Jupiter, Florida, Forenede Stater, 33458
    - Jupiter Medical Center
  - Lakeland, Florida, Forenede Stater, 33805
    - Lakeland Regional Health Hollis Cancer Center
  - Lakeland, Florida, Forenede Stater, 33805
    - The Watson Clinic
  - Miami, Florida, Forenede Stater, 33136
    - University of Miami Miller School of Medicine-Sylvester Cancer Center
  - Miami Beach, Florida, Forenede Stater, 33140
    - Mount Sinai Medical Center
  - Orlando, Florida, Forenede Stater, 32803
    - AdventHealth Orlando
  - Pensacola, Florida, Forenede Stater, 32504
    - Sacred Heart Hospital
  - Tampa, Florida, Forenede Stater, 33612
    - Moffitt Cancer Center
  - West Palm Beach, Florida, Forenede Stater, 33401
    - Florida Cancer Specialists-West Palm Beach
  - Weston, Florida, Forenede Stater, 33331
    - Cleveland Clinic-Weston
- Georgia
  - Albany, Georgia, Forenede Stater, 31701
    - Phoebe Putney Memorial Hospital
  - Athens, Georgia, Forenede Stater, 30607
    - University Cancer and Blood Center LLC
  - Atlanta, Georgia, Forenede Stater, 30308
    - Emory University Hospital Midtown
  - Atlanta, Georgia, Forenede Stater, 30322
    - Emory University Hospital/Winship Cancer Institute
  - Atlanta, Georgia, Forenede Stater, 30342
    - Emory Saint Joseph's Hospital
  - Atlanta, Georgia, Forenede Stater, 30309
    - Piedmont Hospital
  - Atlanta, Georgia, Forenede Stater, 30342
    - Northside Hospital
  - Atlanta, Georgia, Forenede Stater, 30342
    - Atlanta Regional CCOP
  - Augusta, Georgia, Forenede Stater, 30912
    - Augusta University Medical Center
  - Augusta, Georgia, Forenede Stater, 30901
    - Augusta Oncology Associates PC-D'Antignac
  - Austell, Georgia, Forenede Stater, 30106
    - WellStar Cobb Hospital
  - Columbus, Georgia, Forenede Stater, 31904
    - John B Amos Cancer Center
  - Decatur, Georgia, Forenede Stater, 30033
    - Dekalb Medical Center
  - Decatur, Georgia, Forenede Stater, 30033
    - Atlanta VA Medical Center
  - Fayetteville, Georgia, Forenede Stater, 30214
    - Piedmont Fayette Hospital
  - Gainesville, Georgia, Forenede Stater, 30501
    - Northeast Georgia Medical Center-Gainesville
  - Lawrenceville, Georgia, Forenede Stater, 30046
    - Northside Hospital - Gwinnett
  - Macon, Georgia, Forenede Stater, 31201
    - Medical Center of Central Georgia
  - Marietta, Georgia, Forenede Stater, 30060
    - WellStar Kennestone Hospital
  - Riverdale, Georgia, Forenede Stater, 30274
    - Southern Regional Medical Center
  - Rome, Georgia, Forenede Stater, 30165
    - Harbin Clinic Medical Oncology and Clinical Research
  - Savannah, Georgia, Forenede Stater, 31405
    - Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
  - Savannah, Georgia, Forenede Stater, 31404
    - Memorial Health University Medical Center
- Hawaii
  - 'Aiea, Hawaii, Forenede Stater, 96701
    - Pali Momi Medical Center
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Queen's Medical Center
  - Honolulu, Hawaii, Forenede Stater, 96817
    - The Cancer Center of Hawaii-Liliha
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Hawaii Cancer Care Inc - Waterfront Plaza
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Straub Clinic and Hospital
  - Honolulu, Hawaii, Forenede Stater, 96813
    - University of Hawaii Cancer Center
  - Honolulu, Hawaii, Forenede Stater, 96817
    - Hawaii Cancer Care Inc-Liliha
  - Honolulu, Hawaii, Forenede Stater, 96817
    - Queen's Cancer Center - Kuakini
  - Honolulu, Hawaii, Forenede Stater, 96826
    - Kapiolani Medical Center for Women and Children
  - Honolulu, Hawaii, Forenede Stater, 96819
    - Kaiser Permanente Moanalua Medical Center
  - Honolulu, Hawaii, Forenede Stater, 96859
    - Tripler Army Medical Center
  - Kailua, Hawaii, Forenede Stater, 96734
    - Castle Medical Center
  - Lihue, Hawaii, Forenede Stater, 96766
    - Wilcox Memorial Hospital and Kauai Medical Clinic
  - Wailuku, Hawaii, Forenede Stater, 96793
    - Maui Memorial Medical Center
  - Wailuku, Hawaii, Forenede Stater, 96793
    - Pacific Cancer Institute of Maui
- Idaho
  - Boise, Idaho, Forenede Stater, 83706
    - Saint Alphonsus Cancer Care Center-Boise
  - Boise, Idaho, Forenede Stater, 83712
    - Saint Luke's Cancer Institute - Boise
  - Fruitland, Idaho, Forenede Stater, 83619
    - Saint Luke's Cancer Institute - Fruitland
  - Lewiston, Idaho, Forenede Stater, 83501
    - Saint Joseph Regional Medical Center
  - Meridian, Idaho, Forenede Stater, 83642
    - Saint Luke's Cancer Institute - Meridian
  - Nampa, Idaho, Forenede Stater, 83686
    - Saint Luke's Cancer Institute - Nampa
  - Pocatello, Idaho, Forenede Stater, 83201
    - Portneuf Medical Center
  - Twin Falls, Idaho, Forenede Stater, 83301
    - Saint Luke's Cancer Institute - Twin Falls
- Illinois
  - Alton, Illinois, Forenede Stater, 62002
    - Saint Anthony's Health
  - Aurora, Illinois, Forenede Stater, 60504
    - Rush - Copley Medical Center
  - Berwyn, Illinois, Forenede Stater, 60402
    - MacNeal Hospital and Cancer Center
  - Bloomington, Illinois, Forenede Stater, 61704
    - Illinois CancerCare-Bloomington
  - Bloomington, Illinois, Forenede Stater, 61701
    - Saint Joseph Medical Center
  - Canton, Illinois, Forenede Stater, 61520
    - Illinois CancerCare-Canton
  - Canton, Illinois, Forenede Stater, 61520
    - Graham Hospital Association
  - Carthage, Illinois, Forenede Stater, 62321
    - Illinois CancerCare-Carthage
  - Carthage, Illinois, Forenede Stater, 62321
    - Memorial Hospital
  - Chicago, Illinois, Forenede Stater, 60611
    - Northwestern University
  - Chicago, Illinois, Forenede Stater, 60612
    - Rush University Medical Center
  - Chicago, Illinois, Forenede Stater, 60637
    - University of Chicago Comprehensive Cancer Center
  - Chicago, Illinois, Forenede Stater, 60612
    - University of Illinois
  - Chicago, Illinois, Forenede Stater, 60612
    - John H Stroger Jr Hospital of Cook County
  - Chicago, Illinois, Forenede Stater, 60657
    - UChicago Medicine Comprehensive Cancer Center - Saint Joseph Hospital
  - Chicago, Illinois, Forenede Stater, 60608
    - Mount Sinai Hospital Medical Center
  - Chicago, Illinois, Forenede Stater, 60625
    - Swedish Covenant Hospital
  - Chicago, Illinois, Forenede Stater, 60611
    - Hematology and Oncology Associates
  - Chicago, Illinois, Forenede Stater, 60631
    - Presence Resurrection Medical Center
  - Chicago, Illinois, Forenede Stater, 60640
    - Weiss Memorial Hospital
  - Chicago, Illinois, Forenede Stater, 60612
    - Jesse Brown Veterans Affairs Medical Center
  - Decatur, Illinois, Forenede Stater, 62526
    - Decatur Memorial Hospital
  - Decatur, Illinois, Forenede Stater, 62526
    - Heartland Cancer Research NCORP
  - Downers Grove, Illinois, Forenede Stater, 60515
    - Advocate Good Samaritan Hospital
  - Effingham, Illinois, Forenede Stater, 62401
    - Saint Anthony Memorial Hospital
  - Elgin, Illinois, Forenede Stater, 60123
    - Advocate Sherman Hospital
  - Elk Grove Village, Illinois, Forenede Stater, 60007
    - Ascension Alexian Brothers - Elk Grove Village
  - Elmhurst, Illinois, Forenede Stater, 60126
    - Elmhurst Memorial Hospital
  - Eureka, Illinois, Forenede Stater, 61530
    - Illinois CancerCare-Eureka
  - Eureka, Illinois, Forenede Stater, 61530
    - Eureka Hospital
  - Evanston, Illinois, Forenede Stater, 60201
    - NorthShore University HealthSystem-Evanston Hospital
  - Evanston, Illinois, Forenede Stater, 60202
    - Saint Francis Hospital
  - Galesburg, Illinois, Forenede Stater, 61401
    - Western Illinois Cancer Treatment Center
  - Galesburg, Illinois, Forenede Stater, 61401
    - Illinois CancerCare-Galesburg
  - Galesburg, Illinois, Forenede Stater, 61401
    - Galesburg Cottage Hospital
  - Galesburg, Illinois, Forenede Stater, 61401
    - Illinois CancerCare-Cottage
  - Geneva, Illinois, Forenede Stater, 60134
    - Northwestern Medicine Cancer Center Delnor
  - Geneva, Illinois, Forenede Stater, 60134
    - LaGrange Oncology Associates
  - Harvey, Illinois, Forenede Stater, 60426
    - Ingalls Memorial Hospital
  - Havana, Illinois, Forenede Stater, 62644
    - Mason District Hospital
  - Havana, Illinois, Forenede Stater, 62644
    - Illinois CancerCare-Havana
  - Highland Park, Illinois, Forenede Stater, 60035
    - Hematology Oncology Associates of Illinois-Highland Park
  - Hinsdale, Illinois, Forenede Stater, 60521
    - Hinsdale Hematology Oncology Associates Incorporated
  - Hopedale, Illinois, Forenede Stater, 61747
    - Hopedale Medical Complex - Hospital
  - Joliet, Illinois, Forenede Stater, 60435
    - Duly Health and Care Joliet
  - Joliet, Illinois, Forenede Stater, 60432
    - Midwest Center for Hematology Oncology
  - Kankakee, Illinois, Forenede Stater, 60901
    - Presence Saint Mary's Hospital
  - Kewanee, Illinois, Forenede Stater, 61443
    - Illinois CancerCare-Kewanee Clinic
  - La Grange, Illinois, Forenede Stater, 60525
    - AMITA Health Adventist Medical Center
  - Libertyville, Illinois, Forenede Stater, 60048
    - AMG Libertyville - Oncology
  - Macomb, Illinois, Forenede Stater, 61455
    - Illinois CancerCare-Macomb
  - Macomb, Illinois, Forenede Stater, 61455
    - Mcdonough District Hospital
  - Maywood, Illinois, Forenede Stater, 60153
    - Loyola University Medical Center
  - Moline, Illinois, Forenede Stater, 61265
    - Garneau, Stewart C MD (UIA Investigator)
  - Moline, Illinois, Forenede Stater, 61265
    - Porubcin, Michael MD (UIA Investigator)
  - Moline, Illinois, Forenede Stater, 61265
    - Spector, David MD (UIA Investigator)
  - Moline, Illinois, Forenede Stater, 61265
    - Trinity Medical Center
  - Moline, Illinois, Forenede Stater, 61265
    - Sharis, Christine M MD (UIA Investigator)
  - Moline, Illinois, Forenede Stater, 61265
    - Stoffel, Thomas J MD (UIA Investigator)
  - Moline, Illinois, Forenede Stater, 61265
    - Vigliotti, Antonio, P.G. M.D. (UIA Investigator)
  - Monmouth, Illinois, Forenede Stater, 61462
    - Illinois CancerCare-Monmouth
  - Monmouth, Illinois, Forenede Stater, 61462
    - Holy Family Medical Center
  - Mount Vernon, Illinois, Forenede Stater, 62864
    - Good Samaritan Regional Health Center
  - Naperville, Illinois, Forenede Stater, 60540
    - Edward Hospital/Cancer Center
  - Naperville, Illinois, Forenede Stater, 60563
    - DuPage Medical Group-Ogden
  - Niles, Illinois, Forenede Stater, 60714
    - Illinois Cancer Specialists-Niles
  - Normal, Illinois, Forenede Stater, 61761
    - Carle Cancer Institute Normal
  - Normal, Illinois, Forenede Stater, 61761
    - Bromenn Regional Medical Center
  - Normal, Illinois, Forenede Stater, 61761
    - Illinois CancerCare-Community Cancer Center
  - Normal, Illinois, Forenede Stater, 61761
    - Mid-Illinois Hematology Oncology Associates Limited
  - Oak Lawn, Illinois, Forenede Stater, 60453-2699
    - Advocate Christ Medical Center
  - Ottawa, Illinois, Forenede Stater, 61350
    - Illinois CancerCare-Ottawa Clinic
  - Ottawa, Illinois, Forenede Stater, 61350
    - Ottawa Regional Hospital and Healthcare Center
  - Pekin, Illinois, Forenede Stater, 61554
    - Illinois CancerCare-Pekin
  - Pekin, Illinois, Forenede Stater, 61554
    - OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
  - Pekin, Illinois, Forenede Stater, 61554
    - Pekin Hospital
  - Peoria, Illinois, Forenede Stater, 61636
    - Methodist Medical Center of Illinois
  - Peoria, Illinois, Forenede Stater, 61637
    - OSF Saint Francis Medical Center
  - Peoria, Illinois, Forenede Stater, 61615
    - Illinois CancerCare-Peoria
  - Peoria, Illinois, Forenede Stater, 61615
    - OSF Saint Francis Radiation Oncology at Peoria Cancer Center
  - Peoria, Illinois, Forenede Stater, 61614
    - Proctor Hospital
  - Peru, Illinois, Forenede Stater, 61354
    - Illinois CancerCare-Peru
  - Peru, Illinois, Forenede Stater, 61354
    - Valley Radiation Oncology
  - Peru, Illinois, Forenede Stater, 61354
    - Illinois Valley Hospital
  - Princeton, Illinois, Forenede Stater, 61356
    - Illinois CancerCare-Princeton
  - Princeton, Illinois, Forenede Stater, 61356
    - Perry Memorial Hospital
  - River Forest, Illinois, Forenede Stater, 60305
    - West Suburban Medical Center
  - Rockford, Illinois, Forenede Stater, 61114
    - SwedishAmerican Regional Cancer Center/ACT
  - Rockford, Illinois, Forenede Stater, 61108
    - OSF Saint Anthony Medical Center
  - Rockford, Illinois, Forenede Stater, 61104
    - Swedish American Hospital
  - Skokie, Illinois, Forenede Stater, 60076
    - Hematology Oncology Associates of Illinois - Skokie
  - Skokie, Illinois, Forenede Stater, 60076
    - Edward H Kaplan MD and Associates
  - Spring Valley, Illinois, Forenede Stater, 61362
    - Saint Margaret's Hospital
  - Spring Valley, Illinois, Forenede Stater, 61362
    - Illinois CancerCare-Spring Valley
  - Springfield, Illinois, Forenede Stater, 62781
    - Memorial Medical Center
  - Urbana, Illinois, Forenede Stater, 61801
    - Carle Cancer Center
  - Warrenville, Illinois, Forenede Stater, 60555
    - Northwestern Medicine Cancer Center Warrenville
  - Winfield, Illinois, Forenede Stater, 60190
    - Northwestern Medicine Central DuPage Hospital
- Indiana
  - Anderson, Indiana, Forenede Stater, 46016
    - Ascension Saint Vincent Anderson
  - Beech Grove, Indiana, Forenede Stater, 46107
    - Franciscan Saint Francis Health-Beech Grove
  - Elkhart, Indiana, Forenede Stater, 46515
    - Elkhart General Hospital
  - Elkhart, Indiana, Forenede Stater, 46514
    - Michiana Hematology Oncology PC-Elkhart
  - Elkhart, Indiana, Forenede Stater, 46514-2098
    - Elkhart Clinic
  - Fort Wayne, Indiana, Forenede Stater, 46845
    - Fort Wayne Medical Oncology and Hematology Inc-Parkview
  - Indianapolis, Indiana, Forenede Stater, 46237
    - Franciscan Health Indianapolis
  - Indianapolis, Indiana, Forenede Stater, 46202
    - Indiana University/Melvin and Bren Simon Cancer Center
  - Indianapolis, Indiana, Forenede Stater, 46260
    - Ascension Saint Vincent Indianapolis Hospital
  - Indianapolis, Indiana, Forenede Stater, 46202
    - Sidney and Lois Eskenazi Hospital
  - Indianapolis, Indiana, Forenede Stater, 46202
    - Richard L. Roudebush Veterans Affairs Medical Center
  - Kokomo, Indiana, Forenede Stater, 46904
    - Community Howard Regional Health
  - La Porte, Indiana, Forenede Stater, 46350
    - IU Health La Porte Hospital
  - Lafayette, Indiana, Forenede Stater, 47904
    - IU Health Arnett Cancer Care
  - Merrillville, Indiana, Forenede Stater, 46410
    - Premier Oncology Hematology Associates
  - Michigan City, Indiana, Forenede Stater, 46360
    - Franciscan Saint Anthony Health-Michigan City
  - Mishawaka, Indiana, Forenede Stater, 46545
    - Michiana Hematology Oncology PC-Mishawaka
  - Mishawaka, Indiana, Forenede Stater, 46545
    - Saint Joseph Regional Medical Center-Mishawaka
  - Muncie, Indiana, Forenede Stater, 47303
    - IU Health Ball Memorial Hospital
  - Munster, Indiana, Forenede Stater, 46321
    - The Community Hospital
  - Plymouth, Indiana, Forenede Stater, 46563
    - Michiana Hematology Oncology PC-Plymouth
  - Richmond, Indiana, Forenede Stater, 47374
    - Reid Health
  - South Bend, Indiana, Forenede Stater, 46601
    - Memorial Hospital of South Bend
  - South Bend, Indiana, Forenede Stater, 46601
    - Michiana Hematology Oncology PC-South Bend
  - South Bend, Indiana, Forenede Stater, 46628
    - Northern Indiana Cancer Research Consortium
  - South Bend, Indiana, Forenede Stater, 46617
    - South Bend Clinic
  - Westville, Indiana, Forenede Stater, 46391
    - Michiana Hematology Oncology PC-Westville
- Iowa
  - Ames, Iowa, Forenede Stater, 50010
    - McFarland Clinic - Ames
  - Bettendorf, Iowa, Forenede Stater, 52722
    - Constantinou, Costas L MD (UIA Investigator)
  - Bettendorf, Iowa, Forenede Stater, 52722
    - University of Iowa Healthcare Cancer Services Quad Cities
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Mercy Hospital
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Oncology Associates at Mercy Medical Center
  - Cedar Rapids, Iowa, Forenede Stater, 52402
    - Saint Luke's Hospital
  - Cedar Rapids, Iowa, Forenede Stater, 52402
    - Physicians' Clinic of Iowa PC
  - Clive, Iowa, Forenede Stater, 50325
    - Medical Oncology and Hematology Associates-West Des Moines
  - Davenport, Iowa, Forenede Stater, 52803
    - Genesis Medical Center - East Campus
  - Davenport, Iowa, Forenede Stater, 52804
    - Genesis Cancer Care Institute
  - Des Moines, Iowa, Forenede Stater, 50309
    - Iowa Methodist Medical Center
  - Des Moines, Iowa, Forenede Stater, 50314
    - Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forenede Stater, 50309
    - Medical Oncology and Hematology Associates-Des Moines
  - Des Moines, Iowa, Forenede Stater, 50314
    - Mission Cancer and Blood - Laurel
  - Des Moines, Iowa, Forenede Stater, 50316
    - Iowa Lutheran Hospital
  - Des Moines, Iowa, Forenede Stater, 50309
    - Iowa-Wide Oncology Research Coalition NCORP
  - Des Moines, Iowa, Forenede Stater, 50307
    - Mercy Capitol
  - Iowa City, Iowa, Forenede Stater, 52242
    - University of Iowa/Holden Comprehensive Cancer Center
  - Mason City, Iowa, Forenede Stater, 50401
    - Mercy Medical Center - North Iowa
  - Ottumwa, Iowa, Forenede Stater, 52501
    - Ottumwa Regional Health Center
  - Sioux City, Iowa, Forenede Stater, 51101
    - Siouxland Regional Cancer Center
  - Sioux City, Iowa, Forenede Stater, 51102
    - Mercy Medical Center-Sioux City
  - Sioux City, Iowa, Forenede Stater, 51104
    - Saint Luke's Regional Medical Center
  - Waterloo, Iowa, Forenede Stater, 50701
    - Cedar Valley Medical Specialists
  - Waterloo, Iowa, Forenede Stater, 50702
    - MercyOne Waterloo Cancer Center
  - West Des Moines, Iowa, Forenede Stater, 50266-7700
    - Methodist West Hospital
- Kansas
  - Anthony, Kansas, Forenede Stater, 67003
    - Hospital District Sixth of Harper County
  - Chanute, Kansas, Forenede Stater, 66720
    - Cancer Center of Kansas - Chanute
  - Dodge City, Kansas, Forenede Stater, 67801
    - Cancer Center of Kansas - Dodge City
  - El Dorado, Kansas, Forenede Stater, 67042
    - Cancer Center of Kansas - El Dorado
  - Fort Scott, Kansas, Forenede Stater, 66701
    - Cancer Center of Kansas - Fort Scott
  - Great Bend, Kansas, Forenede Stater, 67530
    - Saint Rose Ambulatory and Surgery Center
  - Hays, Kansas, Forenede Stater, 67601
    - HaysMed University of Kansas Health System
  - Hutchinson, Kansas, Forenede Stater, 67502
    - Hutchinson Regional Medical Center
  - Independence, Kansas, Forenede Stater, 67301
    - Cancer Center of Kansas-Independence
  - Kansas City, Kansas, Forenede Stater, 66160
    - University of Kansas Cancer Center
  - Kansas City, Kansas, Forenede Stater, 66112
    - University of Kansas Cancer Center-West
  - Kansas City, Kansas, Forenede Stater, 66112
    - Providence Medical Center
  - Kingman, Kansas, Forenede Stater, 67068
    - Cancer Center of Kansas-Kingman
  - Lawrence, Kansas, Forenede Stater, 66044
    - Lawrence Memorial Hospital
  - Liberal, Kansas, Forenede Stater, 67905
    - Cancer Center of Kansas-Liberal
  - Liberal, Kansas, Forenede Stater, 67901
    - Southwest Medical Center
  - McPherson, Kansas, Forenede Stater, 67460
    - Cancer Center of Kansas - McPherson
  - Newton, Kansas, Forenede Stater, 67114
    - Cancer Center of Kansas - Newton
  - Olathe, Kansas, Forenede Stater, 66061
    - Olathe Cancer Center
  - Overland Park, Kansas, Forenede Stater, 66210
    - University of Kansas Cancer Center-Overland Park
  - Overland Park, Kansas, Forenede Stater, 66209
    - Menorah Medical Center
  - Overland Park, Kansas, Forenede Stater, 66213
    - Saint Luke's South Hospital
  - Parsons, Kansas, Forenede Stater, 67357
    - Cancer Center of Kansas - Parsons
  - Pittsburg, Kansas, Forenede Stater, 66762
    - Ascension Via Christi - Pittsburg
  - Prairie Village, Kansas, Forenede Stater, 66208
    - Kansas City NCI Community Oncology Research Program
  - Pratt, Kansas, Forenede Stater, 67124
    - Cancer Center of Kansas - Pratt
  - Salina, Kansas, Forenede Stater, 67401
    - Salina Regional Health Center
  - Salina, Kansas, Forenede Stater, 67401
    - Cancer Center of Kansas - Salina
  - Shawnee Mission, Kansas, Forenede Stater, 66204
    - Advent Health - Shawnee Mission Medical Center
  - Topeka, Kansas, Forenede Stater, 66606
    - University of Kansas Health System Saint Francis Campus
  - Topeka, Kansas, Forenede Stater, 66606
    - Cotton O'Neil Cancer Center / Stormont Vail Health
  - Wellington, Kansas, Forenede Stater, 67152
    - Cancer Center of Kansas - Wellington
  - Wichita, Kansas, Forenede Stater, 67214
    - Ascension Via Christi Hospitals Wichita
  - Wichita, Kansas, Forenede Stater, 67208
    - Cancer Center of Kansas-Wichita Medical Arts Tower
  - Wichita, Kansas, Forenede Stater, 67214
    - Cancer Center of Kansas - Wichita
  - Wichita, Kansas, Forenede Stater, 67208
    - Associates In Womens Health
  - Wichita, Kansas, Forenede Stater, 67214
    - Wichita NCI Community Oncology Research Program
  - Winfield, Kansas, Forenede Stater, 67156
    - Cancer Center of Kansas - Winfield
- Kentucky
  - Ashland, Kentucky, Forenede Stater, 41101
    - King's Daughter's Medical Center
  - Ashland, Kentucky, Forenede Stater, 41101
    - Our Lady Bellefonte Hospital
  - Lexington, Kentucky, Forenede Stater, 40536
    - University of Kentucky/Markey Cancer Center
  - Louisville, Kentucky, Forenede Stater, 40202
    - The James Graham Brown Cancer Center at University of Louisville
  - Louisville, Kentucky, Forenede Stater, 40207
    - Baptist Health Louisville
  - Louisville, Kentucky, Forenede Stater, 40215
    - Doctors Carrol, Sheth, Raghavan
  - Owensboro, Kentucky, Forenede Stater, 42303
    - Owensboro Health Mitchell Memorial Cancer Center
- Louisiana
  - Baton Rouge, Louisiana, Forenede Stater, 70809
    - Mary Bird Perkins Cancer Center
  - Baton Rouge, Louisiana, Forenede Stater, 70809
    - Ochsner Health Center-Summa
  - Baton Rouge, Louisiana, Forenede Stater, 70806
    - Baton Rouge General Medical Center
  - Baton Rouge, Louisiana, Forenede Stater, 70809
    - Hematology/Oncology Clinic PLLC
  - Covington, Louisiana, Forenede Stater, 70433
    - Ochsner Health Center-Covington
  - Lafayette, Louisiana, Forenede Stater, 70503
    - Cancer Center of Acadiana
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Tulane University School of Medicine
  - New Orleans, Louisiana, Forenede Stater, 70121
    - Ochsner Medical Center Jefferson
  - New Orleans, Louisiana, Forenede Stater, 70112
    - University Medical Center New Orleans
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Louisiana State University Health Science Center
  - New Orleans, Louisiana, Forenede Stater, 70115
    - Ochsner Baptist Medical Center
- Maine
  - Augusta, Maine, Forenede Stater, 04330
    - Harold Alfond Center for Cancer Care
  - Bangor, Maine, Forenede Stater, 04401
    - Eastern Maine Medical Center
  - Lewiston, Maine, Forenede Stater, 04240
    - Central Maine Medical Center
  - Lewiston, Maine, Forenede Stater, 04240
    - Saint Mary's Regional Medical Center
  - Portland, Maine, Forenede Stater, 04101
    - Mercy Hospital
  - Scarborough, Maine, Forenede Stater, 04074
    - Maine Center for Cancer Medicine-Scarborough
  - Waterville, Maine, Forenede Stater, 04901
    - Maine General Medical Center-Thayer
  - York, Maine, Forenede Stater, 03909
    - York Hospital
- Maryland
  - Baltimore, Maryland, Forenede Stater, 21237
    - MedStar Franklin Square Medical Center/Weinberg Cancer Institute
  - Baltimore, Maryland, Forenede Stater, 21287
    - Johns Hopkins University/Sidney Kimmel Cancer Center
  - Baltimore, Maryland, Forenede Stater, 21215
    - Sinai Hospital of Baltimore
  - Baltimore, Maryland, Forenede Stater, 21204
    - Greater Baltimore Medical Center
  - Baltimore, Maryland, Forenede Stater, 21201
    - University of Maryland/Greenebaum Cancer Center
  - Baltimore, Maryland, Forenede Stater, 21201
    - Veterans Administration Medical Center-Baltimore
  - Bel Air, Maryland, Forenede Stater, 21014
    - UM Upper Chesapeake Medical Center
  - Bethesda, Maryland, Forenede Stater, 20889-5600
    - Walter Reed National Military Medical Center
  - Cumberland, Maryland, Forenede Stater, 21502
    - UPMC Western Maryland
  - Easton, Maryland, Forenede Stater, 21601
    - University of Maryland Shore Medical Center at Easton
  - Elkton, Maryland, Forenede Stater, 21921
    - Christiana Care - Union Hospital
  - Frederick, Maryland, Forenede Stater, 21701
    - Frederick Memorial Hospital
  - Hagerstown, Maryland, Forenede Stater, 21742
    - Meritus Medical Center
  - Kensington, Maryland, Forenede Stater, 20895
    - Associates in Oncology Hematology PC -Kensington
  - Rockville, Maryland, Forenede Stater, 20850
    - Maryland Oncology Hematology PA-Aquilino Cancer Center
  - Salisbury, Maryland, Forenede Stater, 21801
    - TidalHealth Peninsula Regional
  - Silver Spring, Maryland, Forenede Stater, 20910
    - Holy Cross Hospital
  - Towson, Maryland, Forenede Stater, 21204
    - UM Saint Joseph Medical Center
- Massachusetts
  - Attleboro, Massachusetts, Forenede Stater, 02703
    - Sturdy Memorial Hospital
  - Beverly, Massachusetts, Forenede Stater, 01915
    - Beverly Hospital
  - Boston, Massachusetts, Forenede Stater, 02215
    - Beth Israel Deaconess Medical Center
  - Boston, Massachusetts, Forenede Stater, 02215
    - Dana-Farber Cancer Institute
  - Boston, Massachusetts, Forenede Stater, 02115
    - Brigham and Women's Hospital
  - Boston, Massachusetts, Forenede Stater, 02111
    - Tufts Medical Center
  - Boston, Massachusetts, Forenede Stater, 02118
    - Boston Medical Center
  - Boston, Massachusetts, Forenede Stater, 02114
    - Massachusetts General Hospital Cancer Center
  - Brighton, Massachusetts, Forenede Stater, 02135
    - Steward Saint Elizabeth's Medical Center
  - Burlington, Massachusetts, Forenede Stater, 01805
    - Lahey Hospital and Medical Center
  - Concord, Massachusetts, Forenede Stater, 01742
    - Commonwealth Hematology Oncology PC-Concord
  - Danvers, Massachusetts, Forenede Stater, 01923
    - Mass General/North Shore Cancer Center
  - Fitchburg, Massachusetts, Forenede Stater, 01420
    - Simonds-Sinon Regional Cancer Center
  - Framingham, Massachusetts, Forenede Stater, 01702
    - MetroWest Medical Center-Framingham Union Hospital
  - Gloucester, Massachusetts, Forenede Stater, 01930
    - Addison Gilbert Hospital
  - Haverhill, Massachusetts, Forenede Stater, 01830
    - Dana Farber Community Cancer Care-Haverhill
  - Methuen, Massachusetts, Forenede Stater, 01844
    - Holy Family Hospital
  - Methuen, Massachusetts, Forenede Stater, 01844
    - Dana Farber-Merrimack Valley
  - Norwood, Massachusetts, Forenede Stater, 02062
    - Norwood Hospital
  - Pittsfield, Massachusetts, Forenede Stater, 01201
    - Berkshire Medical Center - Cancer Center
  - Quincy, Massachusetts, Forenede Stater, 02169
    - Dana Farber Community Cancer Care-Quincy
  - Springfield, Massachusetts, Forenede Stater, 01199
    - Baystate Medical Center
  - Stoneham, Massachusetts, Forenede Stater, 02180
    - Dana Farber Community Cancer Care-Stoneham
  - Westfield, Massachusetts, Forenede Stater, 01085
    - Noble Hospital
  - Weymouth, Massachusetts, Forenede Stater, 02189
    - Dana Farber Community Cancer Care-Weymouth
  - Worcester, Massachusetts, Forenede Stater, 01655
    - UMass Memorial Medical Center - University Campus
  - Worcester, Massachusetts, Forenede Stater, 01605
    - Commonwealth Hematology Oncology PC-Worcester
- Michigan
  - Adrian, Michigan, Forenede Stater, 49221
    - Bixby Medical Center
  - Adrian, Michigan, Forenede Stater, 49221
    - Hickman Cancer Center
  - Ann Arbor, Michigan, Forenede Stater, 48109
    - University of Michigan Comprehensive Cancer Center
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - Saint Joseph Mercy Hospital
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - Michigan Cancer Research Consortium NCORP
  - Battle Creek, Michigan, Forenede Stater, 49017
    - Bronson Battle Creek
  - Bay City, Michigan, Forenede Stater, 48706
    - McLaren Cancer Institute-Bay City
  - Big Rapids, Michigan, Forenede Stater, 49307
    - Spectrum Health Big Rapids Hospital
  - Clarkston, Michigan, Forenede Stater, 48346
    - McLaren Cancer Institute-Clarkston
  - Dearborn, Michigan, Forenede Stater, 48124
    - Beaumont Hospital - Dearborn
  - Detroit, Michigan, Forenede Stater, 48202
    - Henry Ford Hospital
  - Detroit, Michigan, Forenede Stater, 48201
    - Wayne State University/Karmanos Cancer Institute
  - Detroit, Michigan, Forenede Stater, 48236
    - Ascension Saint John Hospital
  - East Lansing, Michigan, Forenede Stater, 48824
    - Michigan State University Clinical Center
  - Escanaba, Michigan, Forenede Stater, 49829
    - Green Bay Oncology - Escanaba
  - Farmington Hills, Michigan, Forenede Stater, 48336
    - Beaumont Hospital - Farmington Hills
  - Flint, Michigan, Forenede Stater, 48532
    - Genesys Regional Medical Center-West Flint Campus
  - Flint, Michigan, Forenede Stater, 48532
    - McLaren Cancer Institute-Flint
  - Flint, Michigan, Forenede Stater, 48532
    - Singh and Arora Hematology Oncology PC
  - Flint, Michigan, Forenede Stater, 48503
    - Hurley Medical Center
  - Flint, Michigan, Forenede Stater, 48503
    - Genesys Hurley Cancer Institute
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Spectrum Health at Butterworth Campus
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Cancer Research Consortium of West Michigan NCORP
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Trinity Health Grand Rapids Hospital
  - Holland, Michigan, Forenede Stater, 49423
    - Holland Community Hospital
  - Iron Mountain, Michigan, Forenede Stater, 49801
    - Green Bay Oncology - Iron Mountain
  - Jackson, Michigan, Forenede Stater, 49201
    - Allegiance Health
  - Kalamazoo, Michigan, Forenede Stater, 49007
    - West Michigan Cancer Center
  - Kalamazoo, Michigan, Forenede Stater, 49007
    - Bronson Methodist Hospital
  - Kalamazoo, Michigan, Forenede Stater, 49048
    - Borgess Medical Center
  - Lansing, Michigan, Forenede Stater, 48910
    - Karmanos Cancer Institute at McLaren Greater Lansing
  - Lansing, Michigan, Forenede Stater, 48912
    - University of Michigan Health - Sparrow Lansing
  - Lapeer, Michigan, Forenede Stater, 48446
    - McLaren Cancer Institute-Lapeer Region
  - Lapeer, Michigan, Forenede Stater, 48446
    - Lapeer Regional Hospital
  - Livonia, Michigan, Forenede Stater, 48154
    - Trinity Health Saint Mary Mercy Livonia Hospital
  - Marquette, Michigan, Forenede Stater, 49855
    - UP Health System Marquette
  - Midland, Michigan, Forenede Stater, 48670
    - MyMichigan Medical Center Midland
  - Monroe, Michigan, Forenede Stater, 48162
    - Mercy Memorial Hospital
  - Monroe, Michigan, Forenede Stater, 48162
    - Toledo Clinic Cancer Centers-Monroe
  - Mount Clemens, Michigan, Forenede Stater, 48043
    - McLaren Cancer Institute-Macomb
  - Muskegon, Michigan, Forenede Stater, 49442
    - Mercy Health Partners-Hackley Campus
  - Muskegon, Michigan, Forenede Stater, 49444
    - Trinity Health Muskegon Hospital
  - Niles, Michigan, Forenede Stater, 49120
    - Corewell Health Lakeland Hospitals - Niles Hospital
  - Petoskey, Michigan, Forenede Stater, 49770
    - McLaren Cancer Institute-Northern Michigan
  - Pontiac, Michigan, Forenede Stater, 48341
    - Saint Joseph Mercy Oakland
  - Port Huron, Michigan, Forenede Stater, 48060
    - Lake Huron Medical Center
  - Reed City, Michigan, Forenede Stater, 49677
    - Corewell Health Reed City Hospital
  - Royal Oak, Michigan, Forenede Stater, 48073
    - William Beaumont Hospital-Royal Oak
  - Saginaw, Michigan, Forenede Stater, 48601
    - Ascension Saint Mary's Hospital
  - Saint Joseph, Michigan, Forenede Stater, 49085
    - Lakeland Medical Center Saint Joseph
  - Saint Joseph, Michigan, Forenede Stater, 49085
    - Oncology Care Associates PLLC
  - Saint Joseph, Michigan, Forenede Stater, 49085
    - Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
  - Southfield, Michigan, Forenede Stater, 48075
    - Ascension Providence Hospitals - Southfield
  - Traverse City, Michigan, Forenede Stater, 49684
    - Munson Medical Center
  - Troy, Michigan, Forenede Stater, 48085
    - William Beaumont Hospital - Troy
  - Warren, Michigan, Forenede Stater, 48093
    - Saint John Macomb-Oakland Hospital
  - Wyoming, Michigan, Forenede Stater, 49519
    - University of Michigan Health - West
- Minnesota
  - Alexandria, Minnesota, Forenede Stater, 56308
    - Medini, Eitan MD (UIA Investigator)
  - Bemidji, Minnesota, Forenede Stater, 56601
    - Sanford Joe Lueken Cancer Center
  - Brainerd, Minnesota, Forenede Stater, 56401
    - Essentia Health Saint Joseph's Medical Center
  - Burnsville, Minnesota, Forenede Stater, 55337
    - Fairview Ridges Hospital
  - Coon Rapids, Minnesota, Forenede Stater, 55433
    - Mercy Hospital
  - Duluth, Minnesota, Forenede Stater, 55805
    - Saint Luke's Hospital of Duluth
  - Duluth, Minnesota, Forenede Stater, 55805
    - Essentia Health Cancer Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - Essentia Health Saint Mary's Medical Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - Miller-Dwan Hospital
  - Edina, Minnesota, Forenede Stater, 55435
    - Fairview Southdale Hospital
  - Fergus Falls, Minnesota, Forenede Stater, 56537
    - Lake Region Healthcare Corporation-Cancer Care
  - Fergus Falls, Minnesota, Forenede Stater, 56537
    - Etzell, Paul S MD (UIA Investigator)
  - Fergus Falls, Minnesota, Forenede Stater, 56537
    - Swenson, Wade II, MD (UIA Investigator)
  - Fridley, Minnesota, Forenede Stater, 55432
    - Unity Hospital
  - Hutchinson, Minnesota, Forenede Stater, 55350
    - Hutchinson Area Health Care
  - Litchfield, Minnesota, Forenede Stater, 55355
    - Meeker County Memorial Hospital
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Saint John's Hospital - Healtheast
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Minnesota Oncology Hematology PA-Maplewood
  - Minneapolis, Minnesota, Forenede Stater, 55415
    - Hennepin County Medical Center
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Abbott-Northwestern Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55455
    - University of Minnesota/Masonic Cancer Center
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Virginia Piper Cancer Institute
  - Minneapolis, Minnesota, Forenede Stater, 55417
    - Minneapolis VA Medical Center
  - New Ulm, Minnesota, Forenede Stater, 56073
    - New Ulm Medical Center
  - Robbinsdale, Minnesota, Forenede Stater, 55422
    - North Memorial Medical Health Center
  - Rochester, Minnesota, Forenede Stater, 55905
    - Mayo Clinic in Rochester
  - Saint Cloud, Minnesota, Forenede Stater, 56303
    - Coborn Cancer Center at Saint Cloud Hospital
  - Saint Cloud, Minnesota, Forenede Stater, 56303
    - Saint Cloud Hospital
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - Park Nicollet Clinic - Saint Louis Park
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - Metro Minnesota Community Oncology Research Consortium
  - Saint Paul, Minnesota, Forenede Stater, 55101
    - Regions Hospital
  - Saint Paul, Minnesota, Forenede Stater, 55102
    - United Hospital
  - Saint Paul, Minnesota, Forenede Stater, 55102
    - Saint Joseph's Hospital - Healtheast
  - Shakopee, Minnesota, Forenede Stater, 55379
    - Saint Francis Regional Medical Center
  - Stillwater, Minnesota, Forenede Stater, 55082
    - Lakeview Hospital
  - Waconia, Minnesota, Forenede Stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forenede Stater, 56201
    - Rice Memorial Hospital
  - Woodbury, Minnesota, Forenede Stater, 55125
    - Minnesota Oncology Hematology PA-Woodbury
  - Woodbury, Minnesota, Forenede Stater, 55125
    - Woodwinds Health Campus
- Mississippi
  - Hattiesburg, Mississippi, Forenede Stater, 39401
    - Hattiesburg Clinic - Hematology/Oncology Clinic
  - Jackson, Mississippi, Forenede Stater, 39216
    - University of Mississippi Medical Center
  - Jackson, Mississippi, Forenede Stater, 39216
    - Veterans Affairs Medical Center
  - Keesler Air Force Base, Mississippi, Forenede Stater, 39534
    - Keesler Medical Center
  - Pascagoula, Mississippi, Forenede Stater, 39581
    - Singing River Hospital
- Missouri
  - Bolivar, Missouri, Forenede Stater, 65613
    - Central Care Cancer Center - Bolivar
  - Branson, Missouri, Forenede Stater, 65616
    - Cox Cancer Center Branson
  - Cape Girardeau, Missouri, Forenede Stater, 63703
    - Saint Francis Medical Center
  - Cape Girardeau, Missouri, Forenede Stater, 63703
    - Southeast Cancer Center
  - Cape Girardeau, Missouri, Forenede Stater, 63701
    - Southeast Missouri Hospital
  - Chesterfield, Missouri, Forenede Stater, 63017
    - Saint Luke's Hospital
  - Columbia, Missouri, Forenede Stater, 65201
    - Veterans Administration
  - Columbia, Missouri, Forenede Stater, 65212
    - MU Health - University Hospital/Ellis Fischel Cancer Center
  - Independence, Missouri, Forenede Stater, 64057
    - Centerpoint Medical Center LLC
  - Jefferson City, Missouri, Forenede Stater, 65109
    - Capital Region Southwest Campus
  - Jefferson City, Missouri, Forenede Stater, 65101
    - Capital Region Medical Center
  - Joplin, Missouri, Forenede Stater, 64804
    - Freeman Health System
  - Joplin, Missouri, Forenede Stater, 64804
    - Mercy Hospital Joplin
  - Kansas City, Missouri, Forenede Stater, 64128
    - Kansas City Veterans Affairs Medical Center
  - Kansas City, Missouri, Forenede Stater, 64154
    - University of Kansas Cancer Center - North
  - Kansas City, Missouri, Forenede Stater, 64116
    - North Kansas City Hospital
  - Kansas City, Missouri, Forenede Stater, 64131
    - The University of Kansas Cancer Center-South
  - Kansas City, Missouri, Forenede Stater, 64111
    - Saint Luke's Hospital of Kansas City
  - Kansas City, Missouri, Forenede Stater, 64132
    - Research Medical Center
  - Kansas City, Missouri, Forenede Stater, 64108
    - Truman Medical Centers
  - Kansas City, Missouri, Forenede Stater, 64118
    - Heartland Hematology and Oncology Associates Incorporated
  - Kansas City, Missouri, Forenede Stater, 64114
    - Saint Joseph Health Center
  - Lee's Summit, Missouri, Forenede Stater, 64064
    - University of Kansas Cancer Center - Lee's Summit
  - Lee's Summit, Missouri, Forenede Stater, 64086
    - Saint Luke's East - Lee's Summit
  - Liberty, Missouri, Forenede Stater, 64068
    - Liberty Radiation Oncology Center
  - Rolla, Missouri, Forenede Stater, 65401
    - Delbert Day Cancer Institute at PCRMC
  - Rolla, Missouri, Forenede Stater, 65401
    - Mercy Clinic-Rolla-Cancer and Hematology
  - Saint Joseph, Missouri, Forenede Stater, 64506
    - Heartland Regional Medical Center
  - Saint Joseph, Missouri, Forenede Stater, 64507
    - Saint Joseph Oncology Inc
  - Saint Louis, Missouri, Forenede Stater, 63110
    - Washington University School of Medicine
  - Saint Louis, Missouri, Forenede Stater, 63131
    - Missouri Baptist Medical Center
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Mercy Hospital Saint Louis
  - Saint Louis, Missouri, Forenede Stater, 63128
    - Mercy Hospital South
  - Saint Louis, Missouri, Forenede Stater, 63136
    - Siteman Cancer Center at Christian Hospital
  - Saint Louis, Missouri, Forenede Stater, 63109
    - Saint Louis Cancer and Breast Institute-South City
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Saint Louis-Cape Girardeau CCOP
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Center for Cancer Care and Research
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Comprehensive Cancer Care PC
  - Springfield, Missouri, Forenede Stater, 65804
    - Cancer Research for the Ozarks NCORP
  - Springfield, Missouri, Forenede Stater, 65807
    - CoxHealth South Hospital
  - Springfield, Missouri, Forenede Stater, 65804
    - Mercy Hospital Springfield
- Montana
  - Billings, Montana, Forenede Stater, 59101
    - Billings Clinic Cancer Center
  - Billings, Montana, Forenede Stater, 59101
    - Saint Vincent Healthcare
  - Billings, Montana, Forenede Stater, 59102
    - Montana Cancer Consortium NCORP
  - Billings, Montana, Forenede Stater, 59101
    - Northern Rockies Radiation Oncology Center
  - Billings, Montana, Forenede Stater, 59102
    - Saint Vincent Frontier Cancer Center
  - Bozeman, Montana, Forenede Stater, 59715
    - Bozeman Deaconess Hospital
  - Butte, Montana, Forenede Stater, 59701
    - Saint James Community Hospital and Cancer Treatment Center
  - Great Falls, Montana, Forenede Stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forenede Stater, 59405
    - Benefis Healthcare- Sletten Cancer Institute
  - Great Falls, Montana, Forenede Stater, 59405
    - Berdeaux, Donald MD (UIA Investigator)
  - Havre, Montana, Forenede Stater, 59501
    - Northern Montana Hospital
  - Helena, Montana, Forenede Stater, 59601
    - Saint Peter's Community Hospital
  - Kalispell, Montana, Forenede Stater, 59901
    - Kalispell Regional Medical Center
  - Kalispell, Montana, Forenede Stater, 59901
    - Glacier Oncology PLLC
  - Kalispell, Montana, Forenede Stater, 59901
    - Kalispell Medical Oncology
  - Missoula, Montana, Forenede Stater, 59804
    - Community Medical Hospital
  - Missoula, Montana, Forenede Stater, 59802
    - Saint Patrick Hospital - Community Hospital
  - Missoula, Montana, Forenede Stater, 59804
    - Guardian Oncology and Center for Wellness
  - Missoula, Montana, Forenede Stater, 59802
    - Montana Cancer Specialists
- Nebraska
  - Grand Island, Nebraska, Forenede Stater, 68803
    - CHI Health Saint Francis
  - Kearney, Nebraska, Forenede Stater, 68847
    - CHI Health Good Samaritan
  - Lincoln, Nebraska, Forenede Stater, 68510
    - Nebraska Cancer Research Center
  - North Platte, Nebraska, Forenede Stater, 69101
    - Great Plains Health Callahan Cancer Center
  - Omaha, Nebraska, Forenede Stater, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forenede Stater, 68124
    - Alegent Health Bergan Mercy Medical Center
  - Omaha, Nebraska, Forenede Stater, 68122
    - Alegent Health Immanuel Medical Center
  - Omaha, Nebraska, Forenede Stater, 68130
    - Alegent Health Lakeside Hospital
  - Omaha, Nebraska, Forenede Stater, 68131
    - Creighton University Medical Center
  - Omaha, Nebraska, Forenede Stater, 68106
    - Missouri Valley Cancer Consortium
- Nevada
  - Las Vegas, Nevada, Forenede Stater, 89102
    - University Medical Center of Southern Nevada
  - Las Vegas, Nevada, Forenede Stater, 89169
    - Nevada Cancer Research Foundation NCORP
  - Las Vegas, Nevada, Forenede Stater, 89135
    - Nevada Cancer Institute-Summerlin Campus
  - Reno, Nevada, Forenede Stater, 89502
    - Renown Regional Medical Center
- New Hampshire
  - Concord, New Hampshire, Forenede Stater, 03301
    - New Hampshire Oncology Hematology PA-Concord
  - Dover, New Hampshire, Forenede Stater, 03820
    - Wentworth-Douglass Hospital
  - Exeter, New Hampshire, Forenede Stater, 03833
    - Exeter Hospital
  - Keene, New Hampshire, Forenede Stater, 03431
    - Cheshire Medical Center-Dartmouth-Hitchcock Keene
  - Laconia, New Hampshire, Forenede Stater, 03246
    - LRGHealthcare-Lakes Region General Hospital
  - Manchester, New Hampshire, Forenede Stater, 03103
    - Solinsky Center for Cancer Care
  - Nashua, New Hampshire, Forenede Stater, 03060
    - Saint Joseph Hospital
  - Nashua, New Hampshire, Forenede Stater, 03060
    - Foundation Medical Partners
  - Portsmouth, New Hampshire, Forenede Stater, 03802
    - Portsmouth Regional Hospital
- New Jersey
  - Brick, New Jersey, Forenede Stater, 08724
    - Ocean University Medical Center
  - Camden, New Jersey, Forenede Stater, 08103
    - Cooper Hospital University Medical Center
  - East Orange, New Jersey, Forenede Stater, 07018-1095
    - Veterans Adminstration New Jersey Health Care System
  - Englewood, New Jersey, Forenede Stater, 07631
    - Englewood Hospital and Medical Center
  - Flemington, New Jersey, Forenede Stater, 08822
    - Hunterdon Medical Center
  - Freehold, New Jersey, Forenede Stater, 07728
    - CentraState Medical Center
  - Hamilton, New Jersey, Forenede Stater, 08690
    - The Cancer Institute of New Jersey Hamilton
  - Morristown, New Jersey, Forenede Stater, 07960
    - Morristown Medical Center
  - Mount Holly, New Jersey, Forenede Stater, 08060
    - Virtua Memorial
  - Neptune, New Jersey, Forenede Stater, 07753
    - Jersey Shore Medical Center
  - New Brunswick, New Jersey, Forenede Stater, 08903
    - Rutgers Cancer Institute of New Jersey
  - New Brunswick, New Jersey, Forenede Stater, 08901
    - Saint Peter's University Hospital
  - Newark, New Jersey, Forenede Stater, 07112
    - Newark Beth Israel Medical Center
  - Pennington, New Jersey, Forenede Stater, 08534
    - Capital Health Medical Center-Hopewell
  - Phillipsburg, New Jersey, Forenede Stater, 08865
    - Saint Luke's Hospital-Warren Campus
  - Plainsboro, New Jersey, Forenede Stater, 08536
    - Penn Medicine Princeton Health
  - Pomona, New Jersey, Forenede Stater, 08240
    - AtlantiCare Regional Medical Center -Main Campus
  - Red Bank, New Jersey, Forenede Stater, 07701
    - Riverview Medical Center/Booker Cancer Center
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - Valley Hospital
  - Somerville, New Jersey, Forenede Stater, 08876
    - Robert Wood Johnson University Hospital Somerset
  - Sparta, New Jersey, Forenede Stater, 07871
    - Sparta Cancer Treatment Center
  - Summit, New Jersey, Forenede Stater, 07902
    - Overlook Hospital
  - Trenton, New Jersey, Forenede Stater, 08629
    - Saint Francis Medical Center
  - Vineland, New Jersey, Forenede Stater, 08360
    - Inspira Medical Center Vineland
  - Voorhees, New Jersey, Forenede Stater, 08043
    - Virtua Voorhees
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87102
    - University of New Mexico Cancer Center
  - Albuquerque, New Mexico, Forenede Stater, 87102
    - Lovelace Medical Center-Saint Joseph Square
  - Albuquerque, New Mexico, Forenede Stater, 87106
    - Hematology Oncology Associates
  - Albuquerque, New Mexico, Forenede Stater, 87110
    - Presbyterian Kaseman Hospital
  - Las Cruces, New Mexico, Forenede Stater, 88011
    - Memorial Medical Center - Las Cruces
  - Las Cruces, New Mexico, Forenede Stater, 88011
    - Memorial Medical Center-Main Campus
  - Santa Fe, New Mexico, Forenede Stater, 87505
    - Christus Saint Vincent Regional Cancer Center
- New York
  - Albany, New York, Forenede Stater, 12206
    - New York Oncology Hematology PC - Albany
  - Albany, New York, Forenede Stater, 12208
    - New York Oncology Hematology PC - Albany Medical Center
  - Bronx, New York, Forenede Stater, 10467
    - Montefiore Medical Center - Moses Campus
  - Bronx, New York, Forenede Stater, 10461
    - Montefiore Medical Center-Weiler Hospital
  - Brooklyn, New York, Forenede Stater, 11219
    - Maimonides Medical Center
  - Brooklyn, New York, Forenede Stater, 11203
    - Kings County Hospital
  - Brooklyn, New York, Forenede Stater, 11235
    - Coney Island Hospital
  - Brooklyn, New York, Forenede Stater, 11209
    - Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus
  - Brooklyn, New York, Forenede Stater, 11203
    - State University of New York Downstate Medical Center
  - Buffalo, New York, Forenede Stater, 14215
    - Veterans Affairs Western New York Health Care System-Buffalo
  - Clifton Park, New York, Forenede Stater, 12065
    - New York Oncology Hematology PC - Clifton Park
  - Clifton Springs, New York, Forenede Stater, 14432
    - Finger Lakes Hematology and Oncology
  - Cooperstown, New York, Forenede Stater, 13326
    - Mary Imogene Bassett Hospital
  - East Syracuse, New York, Forenede Stater, 13057
    - Hematology Oncology Associates of Central New York-East Syracuse
  - Elmira, New York, Forenede Stater, 14905
    - Arnot Ogden Medical Center/Falck Cancer Center
  - Glens Falls, New York, Forenede Stater, 12801
    - Glens Falls Hospital
  - Glens Falls, New York, Forenede Stater, 12801
    - Adirondack Cancer Center
  - Hudson, New York, Forenede Stater, 12534
    - New York Oncology Hematology PC-Hudson
  - Lake Success, New York, Forenede Stater, 11042
    - Northwell Health NCORP
  - Lake Success, New York, Forenede Stater, 11042
    - Northwell Health/Center for Advanced Medicine
  - Manhasset, New York, Forenede Stater, 11030
    - North Shore University Hospital
  - Middletown, New York, Forenede Stater, 10940
    - Garnet Health Medical Center
  - Mineola, New York, Forenede Stater, 11501
    - NYU Winthrop Hospital
  - Mount Kisco, New York, Forenede Stater, 10549
    - Northern Westchester Hospital
  - Mount Kisco, New York, Forenede Stater, 10549
    - Mount Kisco Medical Group
  - New Hyde Park, New York, Forenede Stater, 11040
    - Long Island Jewish Medical Center
  - New York, New York, Forenede Stater, 10019
    - Mount Sinai West
  - New York, New York, Forenede Stater, 10032
    - NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
  - New York, New York, Forenede Stater, 10065
    - NYP/Weill Cornell Medical Center
  - New York, New York, Forenede Stater, 10016
    - Laura and Isaac Perlmutter Cancer Center at NYU Langone
  - New York, New York, Forenede Stater, 10003
    - Mount Sinai Union Square
  - Nyack, New York, Forenede Stater, 10960
    - Nyack Hospital
  - Poughkeepsie, New York, Forenede Stater, 12601
    - Vassar Brothers Medical Center
  - Poughkeepsie, New York, Forenede Stater, 12601
    - MidHudson Regional Hospital of Westchester Medical Center
  - Poughkeepsie, New York, Forenede Stater, 12601
    - Hudson Valley Hematology Oncology Associates
  - Poughkeepsie, New York, Forenede Stater, 12601
    - The Dyson Center for Cancer Care
  - Rochester, New York, Forenede Stater, 14642
    - University of Rochester
  - Rochester, New York, Forenede Stater, 14620
    - Highland Hospital
  - Rochester, New York, Forenede Stater, 14623
    - Interlakes Foundation Inc-Rochester
  - Staten Island, New York, Forenede Stater, 10305
    - Staten Island University Hospital
  - Stony Brook, New York, Forenede Stater, 11794
    - Stony Brook University Medical Center
  - Syracuse, New York, Forenede Stater, 13210
    - State University of New York Upstate Medical University
  - Syracuse, New York, Forenede Stater, 13210
    - Syracuse Veterans Administration Medical Center
  - Troy, New York, Forenede Stater, 12180
    - New York Oncology Hematology PC - Troy
  - Utica, New York, Forenede Stater, 13502
    - Faxton-Saint Luke's Healthcare
  - White Plains, New York, Forenede Stater, 10601
    - Dickstein Cancer Treatment Center
- North Carolina
  - Asheboro, North Carolina, Forenede Stater, 27203
    - Randolph Hospital
  - Asheville, North Carolina, Forenede Stater, 28801
    - Mission Hospital
  - Burlington, North Carolina, Forenede Stater, 27215
    - Cone Health Cancer Center at Alamance Regional
  - Cary, North Carolina, Forenede Stater, 27518
    - Waverly Hematology Oncology
  - Chapel Hill, North Carolina, Forenede Stater, 27599
    - UNC Lineberger Comprehensive Cancer Center
  - Charlotte, North Carolina, Forenede Stater, 28203
    - Carolinas Medical Center/Levine Cancer Institute
  - Charlotte, North Carolina, Forenede Stater, 28204
    - Novant Health Presbyterian Medical Center
  - Concord, North Carolina, Forenede Stater, 28025
    - Atrium Health Cabarrus/LCI-Concord
  - Durham, North Carolina, Forenede Stater, 27705
    - Durham VA Medical Center
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Southeastern Medical Oncology Center-Goldsboro
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Wayne Memorial Hospital
  - Greensboro, North Carolina, Forenede Stater, 27403
    - Cone Health Cancer Center
  - Hendersonville, North Carolina, Forenede Stater, 28791
    - Margaret R Pardee Memorial Hospital
  - Hendersonville, North Carolina, Forenede Stater, 28792
    - AdventHealth Hendersonville
  - Kinston, North Carolina, Forenede Stater, 28501
    - Vidant Oncology-Kinston
  - Monroe, North Carolina, Forenede Stater, 28112
    - Atrium Health Union/LCI-Union
  - Pinehurst, North Carolina, Forenede Stater, 28374
    - FirstHealth of the Carolinas-Moore Regional Hospital
  - Raleigh, North Carolina, Forenede Stater, 27607
    - UNC Rex Healthcare
  - Reidsville, North Carolina, Forenede Stater, 27320
    - Annie Penn Memorial Hospital
  - Rutherfordton, North Carolina, Forenede Stater, 28139
    - Rutherford Hospital
  - Shelby, North Carolina, Forenede Stater, 28150
    - Atrium Health Cleveland/LCI-Cleveland
  - Statesville, North Carolina, Forenede Stater, 28677
    - Iredell Memorial Hospital
  - Washington, North Carolina, Forenede Stater, 27889
    - Marion L Shepard Cancer Center at Vidant Beaufort Hospital
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Novant Health Forsyth Medical Center
  - Winston-Salem, North Carolina, Forenede Stater, 27104
    - Southeast Clinical Oncology Research Consortium NCORP
- North Dakota
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Sanford Bismarck Medical Center
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Mid Dakota Clinic
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Saint Alexius Medical Center
  - Fargo, North Dakota, Forenede Stater, 58122
    - Sanford Roger Maris Cancer Center
  - Fargo, North Dakota, Forenede Stater, 58122
    - Sanford Broadway Medical Center
  - Fargo, North Dakota, Forenede Stater, 58122
    - Sanford Clinic North-Fargo
  - Fargo, North Dakota, Forenede Stater, 58102
    - Veterans Administration Medical Center
  - Grand Forks, North Dakota, Forenede Stater, 58201
    - Altru Cancer Center
- Ohio
  - Akron, Ohio, Forenede Stater, 44307
    - Cleveland Clinic Akron General
  - Akron, Ohio, Forenede Stater, 44304
    - Summa Health System - Akron Campus
  - Barberton, Ohio, Forenede Stater, 44203
    - Summa Health System - Barberton Campus
  - Beachwood, Ohio, Forenede Stater, 44122
    - UHHS-Chagrin Highlands Medical Center
  - Beachwood, Ohio, Forenede Stater, 44122
    - Cleveland Clinic Cancer Center Beachwood
  - Bellefontaine, Ohio, Forenede Stater, 43311
    - Mary Rutan Hospital
  - Bowling Green, Ohio, Forenede Stater, 43402
    - Toledo Clinic Cancer Centers-Bowling Green
  - Canton, Ohio, Forenede Stater, 44708
    - Cleveland Clinic Mercy Hospital
  - Canton, Ohio, Forenede Stater, 44710
    - Aultman Health Foundation
  - Chardon, Ohio, Forenede Stater, 44024
    - Geauga Hospital
  - Chillicothe, Ohio, Forenede Stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forenede Stater, 45219
    - The Christ Hospital
  - Cincinnati, Ohio, Forenede Stater, 45219
    - University of Cincinnati Cancer Center-UC Medical Center
  - Cleveland, Ohio, Forenede Stater, 44106
    - Case Western Reserve University
  - Cleveland, Ohio, Forenede Stater, 44109
    - MetroHealth Medical Center
  - Cleveland, Ohio, Forenede Stater, 44195
    - Cleveland Clinic Foundation
  - Cleveland, Ohio, Forenede Stater, 44111
    - Cleveland Clinic Cancer Center/Fairview Hospital
  - Clyde, Ohio, Forenede Stater, 43410
    - North Coast Cancer Care-Clyde
  - Columbus, Ohio, Forenede Stater, 43214
    - Riverside Methodist Hospital
  - Columbus, Ohio, Forenede Stater, 43210
    - Ohio State University Comprehensive Cancer Center
  - Columbus, Ohio, Forenede Stater, 43219
    - The Mark H Zangmeister Center
  - Columbus, Ohio, Forenede Stater, 43228
    - Doctors Hospital
  - Columbus, Ohio, Forenede Stater, 43213
    - Mount Carmel East Hospital
  - Columbus, Ohio, Forenede Stater, 43215
    - Grant Medical Center
  - Columbus, Ohio, Forenede Stater, 43222
    - Mount Carmel Health Center West
  - Columbus, Ohio, Forenede Stater, 43215
    - Columbus NCI Community Oncology Research Program
  - Dayton, Ohio, Forenede Stater, 45406
    - Good Samaritan Hospital - Dayton
  - Dayton, Ohio, Forenede Stater, 45409
    - Miami Valley Hospital
  - Dayton, Ohio, Forenede Stater, 45415
    - Miami Valley Hospital North
  - Dayton, Ohio, Forenede Stater, 45405
    - Grandview Hospital
  - Dayton, Ohio, Forenede Stater, 45459
    - Dayton NCI Community Oncology Research Program
  - Dayton, Ohio, Forenede Stater, 45428
    - Dayton Veterans Affairs Medical Center
  - Delaware, Ohio, Forenede Stater, 43015
    - Grady Memorial Hospital
  - Elyria, Ohio, Forenede Stater, 44035
    - Mercy Cancer Center-Elyria
  - Elyria, Ohio, Forenede Stater, 44035
    - Hematology Oncology Center Incorporated
  - Findlay, Ohio, Forenede Stater, 45840
    - Blanchard Valley Hospital
  - Franklin, Ohio, Forenede Stater, 45005-1066
    - Atrium Medical Center-Middletown Regional Hospital
  - Fremont, Ohio, Forenede Stater, 43420
    - Fremont Memorial Hospital
  - Greenville, Ohio, Forenede Stater, 45331
    - Wayne Hospital
  - Independence, Ohio, Forenede Stater, 44131
    - Cleveland Clinic Cancer Center Independence
  - Kettering, Ohio, Forenede Stater, 45429
    - Kettering Medical Center
  - Lancaster, Ohio, Forenede Stater, 43130
    - Fairfield Medical Center
  - Lima, Ohio, Forenede Stater, 45801
    - Saint Rita's Medical Center
  - Lima, Ohio, Forenede Stater, 45804
    - Lima Memorial Hospital
  - Mansfield, Ohio, Forenede Stater, 44903
    - OhioHealth Mansfield Hospital
  - Marietta, Ohio, Forenede Stater, 45750
    - Marietta Memorial Hospital
  - Maumee, Ohio, Forenede Stater, 43537
    - Toledo Clinic Cancer Centers-Maumee
  - Maumee, Ohio, Forenede Stater, 43537
    - Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
  - Maumee, Ohio, Forenede Stater, 43537
    - Saint Luke's Hospital
  - Mayfield Heights, Ohio, Forenede Stater, 44124
    - Hillcrest Hospital Cancer Center
  - Mentor, Ohio, Forenede Stater, 44060
    - UH Seidman Cancer Center at Lake Health Mentor Campus
  - Middleburg Heights, Ohio, Forenede Stater, 44130
    - UH Seidman Cancer Center at Southwest General Hospital
  - Mount Vernon, Ohio, Forenede Stater, 43050
    - Knox Community Hospital
  - Newark, Ohio, Forenede Stater, 43055
    - Licking Memorial Hospital
  - Norwalk, Ohio, Forenede Stater, 44857
    - Fisher-Titus Medical Center
  - Oregon, Ohio, Forenede Stater, 43616
    - Saint Charles Hospital
  - Oregon, Ohio, Forenede Stater, 43616
    - Toledo Clinic Cancer Centers-Oregon
  - Parma, Ohio, Forenede Stater, 44129
    - University Hospitals Parma Medical Center
  - Portsmouth, Ohio, Forenede Stater, 45662
    - Southern Ohio Medical Center
  - Sandusky, Ohio, Forenede Stater, 44870
    - North Coast Cancer Care
  - Sandusky, Ohio, Forenede Stater, 44870
    - UH Seidman Cancer Center at Firelands Regional Medical Center
  - Sandusky, Ohio, Forenede Stater, 44870
    - Firelands Regional Medical Center
  - Springfield, Ohio, Forenede Stater, 45505
    - Springfield Regional Medical Center
  - Steubenville, Ohio, Forenede Stater, 43952
    - Trinity's Tony Teramana Cancer Center
  - Strongsville, Ohio, Forenede Stater, 44136
    - Cleveland Clinic Cancer Center Strongsville
  - Sylvania, Ohio, Forenede Stater, 43560
    - ProMedica Flower Hospital
  - Tiffin, Ohio, Forenede Stater, 44883
    - Mercy Hospital of Tiffin
  - Toledo, Ohio, Forenede Stater, 43606
    - ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
  - Toledo, Ohio, Forenede Stater, 43608
    - Saint Vincent Mercy Medical Center
  - Toledo, Ohio, Forenede Stater, 43623
    - Mercy Health - Saint Anne Hospital
  - Toledo, Ohio, Forenede Stater, 43623
    - Toledo Clinic Cancer Centers-Toledo
  - Toledo, Ohio, Forenede Stater, 43614
    - University of Toledo
  - Toledo, Ohio, Forenede Stater, 43617
    - Toledo Community Hospital Oncology Program CCOP
  - Troy, Ohio, Forenede Stater, 45373
    - Upper Valley Medical Center
  - Wauseon, Ohio, Forenede Stater, 43567
    - Fulton County Health Center
  - Westerville, Ohio, Forenede Stater, 43081
    - Saint Ann's Hospital
  - Westlake, Ohio, Forenede Stater, 44145
    - UHHS-Westlake Medical Center
  - Wilmington, Ohio, Forenede Stater, 45177
    - Clinton Memorial Hospital
  - Wooster, Ohio, Forenede Stater, 44691
    - Cleveland Clinic Wooster Family Health and Surgery Center
  - Wright-Patterson Air Force Base, Ohio, Forenede Stater, 45433
    - Wright-Patterson Medical Center
  - Xenia, Ohio, Forenede Stater, 45385
    - Greene Memorial Hospital
  - Youngstown, Ohio, Forenede Stater, 44501
    - Forum Health Cancer Care Center
  - Zanesville, Ohio, Forenede Stater, 43701
    - Genesis Healthcare System Cancer Care Center
- Oklahoma
  - Lawton, Oklahoma, Forenede Stater, 73505
    - Cancer Centers of Southwest Oklahoma Research
  - Norman, Oklahoma, Forenede Stater, 73071
    - Cancer Care Associates-Norman
  - Oklahoma City, Oklahoma, Forenede Stater, 73104
    - University of Oklahoma Health Sciences Center
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Mercy Hospital Oklahoma City
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Mercy Physicians of Oklahoma-Lakeside
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Cancer Care Associates
  - Tulsa, Oklahoma, Forenede Stater, 74136
    - Natalie Warren Bryant Cancer Center at Saint Francis
- Oregon
  - Bend, Oregon, Forenede Stater, 97701
    - Saint Charles Health System
  - Clackamas, Oregon, Forenede Stater, 97015
    - Clackamas Radiation Oncology Center
  - Coos Bay, Oregon, Forenede Stater, 97420
    - Bay Area Hospital
  - Grants Pass, Oregon, Forenede Stater, 97527
    - Three Rivers Community Hospital
  - Gresham, Oregon, Forenede Stater, 97030
    - Legacy Mount Hood Medical Center
  - Klamath Falls, Oregon, Forenede Stater, 97601
    - Sky Lakes Medical Center - Cancer Treatment Center
  - Medford, Oregon, Forenede Stater, 97504
    - Asante Health System
  - Medford, Oregon, Forenede Stater, 97504
    - Providence Medford Medical Center
  - Medford, Oregon, Forenede Stater, 97504
    - Rogue Valley Medical Center
  - Milwaukie, Oregon, Forenede Stater, 97222
    - Providence Milwaukie Hospital
  - Newberg, Oregon, Forenede Stater, 97132
    - Providence Newberg Medical Center
  - Oregon City, Oregon, Forenede Stater, 97045
    - Providence Willamette Falls Medical Center
  - Portland, Oregon, Forenede Stater, 97239
    - Oregon Health and Science University
  - Portland, Oregon, Forenede Stater, 97210
    - Legacy Good Samaritan Hospital and Medical Center
  - Portland, Oregon, Forenede Stater, 97213
    - Providence Portland Medical Center
  - Portland, Oregon, Forenede Stater, 97225
    - Providence Saint Vincent Medical Center
  - Portland, Oregon, Forenede Stater, 97227
    - Kaiser Permanente Northwest
  - Portland, Oregon, Forenede Stater, 97227
    - Legacy Emanuel Hospital and Health Center
  - Portland, Oregon, Forenede Stater, 97216
    - Adventist Medical Center
  - Portland, Oregon, Forenede Stater, 97227
    - Compass Oncology Rose Quarter
  - Salem, Oregon, Forenede Stater, 97301
    - Salem Hospital
  - The Dalles, Oregon, Forenede Stater, 97058
    - Mid-Columbia Medical Center/Celilo Cancer Center
  - Tualatin, Oregon, Forenede Stater, 97062
    - Legacy Meridian Park Hospital
- Pennsylvania
  - Abington, Pennsylvania, Forenede Stater, 19001
    - Jefferson Abington Hospital
  - Allentown, Pennsylvania, Forenede Stater, 18103
    - Lehigh Valley Hospital-Cedar Crest
  - Bethlehem, Pennsylvania, Forenede Stater, 18017
    - Lehigh Valley Hospital - Muhlenberg
  - Bethlehem, Pennsylvania, Forenede Stater, 18015
    - Saint Luke's University Hospital-Bethlehem Campus
  - Bryn Mawr, Pennsylvania, Forenede Stater, 19010
    - Bryn Mawr Hospital
  - Butler, Pennsylvania, Forenede Stater, 16001
    - Butler Memorial Hospital
  - Danville, Pennsylvania, Forenede Stater, 17822
    - Geisinger Medical Center
  - Darby, Pennsylvania, Forenede Stater, 19023-1291
    - Mercy Fitzgerald Hospital
  - Doylestown, Pennsylvania, Forenede Stater, 18901
    - Doylestown Hospital
  - Drexel Hill, Pennsylvania, Forenede Stater, 19026
    - Delaware County Memorial Hospital
  - DuBois, Pennsylvania, Forenede Stater, 15801
    - Oncology Hematology Associates of Northern Pennsylvania
  - East Stroudsburg, Pennsylvania, Forenede Stater, 18301
    - Pocono Medical Center
  - Easton, Pennsylvania, Forenede Stater, 18042
    - Easton Hospital
  - Ephrata, Pennsylvania, Forenede Stater, 17522
    - Ephrata Cancer Center
  - Erie, Pennsylvania, Forenede Stater, 16505
    - UPMC Hillman Cancer Center Erie
  - Erie, Pennsylvania, Forenede Stater, 16550
    - UPMC Hamot
  - Gettysburg, Pennsylvania, Forenede Stater, 17325
    - Adams Cancer Center
  - Hanover, Pennsylvania, Forenede Stater, 17331
    - Cherry Tree Cancer Center
  - Harrisburg, Pennsylvania, Forenede Stater, 17109
    - UPMC Pinnacle Cancer Center/Community Osteopathic Campus
  - Hazleton, Pennsylvania, Forenede Stater, 18201
    - Geisinger Medical Center-Cancer Center Hazleton
  - Hershey, Pennsylvania, Forenede Stater, 17033-0850
    - Penn State Milton S Hershey Medical Center
  - Lancaster, Pennsylvania, Forenede Stater, 17602
    - Lancaster General Hospital
  - Langhorne, Pennsylvania, Forenede Stater, 19047
    - Saint Mary Medical and Regional Cancer Center
  - Lemoyne, Pennsylvania, Forenede Stater, 17043
    - Central PA Hematology-Medical Oncology Associates PC
  - Lewistown, Pennsylvania, Forenede Stater, 17044
    - Lewistown Hospital
  - Meadowbrook, Pennsylvania, Forenede Stater, 19046
    - Holy Redeemer Hospital and Medical Center
  - Media, Pennsylvania, Forenede Stater, 19063
    - Riddle Memorial Hospital
  - Monroeville, Pennsylvania, Forenede Stater, 15146
    - Forbes Hospital
  - Natrona Heights, Pennsylvania, Forenede Stater, 15065
    - Allegheny Valley Hospital
  - Paoli, Pennsylvania, Forenede Stater, 19301
    - Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19111
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Thomas Jefferson University Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19114
    - Jefferson Torresdale Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19104
    - University of Pennsylvania/Abramson Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19141
    - Einstein Medical Center Philadelphia
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Pennsylvania Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19143
    - Mercy Hospital of Philadelphia
  - Philadelphia, Pennsylvania, Forenede Stater, 19118
    - Chestnut Hill Health System
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - Allegheny General Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15232
    - University of Pittsburgh Cancer Institute (UPCI)
  - Pittsburgh, Pennsylvania, Forenede Stater, 15240
    - VA Pittsburgh Healthcare System
  - Pottstown, Pennsylvania, Forenede Stater, 19464
    - Pottstown Hospital
  - Reading, Pennsylvania, Forenede Stater, 19605
    - Penn State Health Saint Joseph Medical Center
  - Sayre, Pennsylvania, Forenede Stater, 18840
    - Guthrie Medical Group PC-Robert Packer Hospital
  - Scranton, Pennsylvania, Forenede Stater, 18510
    - Scranton Hematology Oncology
  - Scranton, Pennsylvania, Forenede Stater, 18501
    - Mercy Hospital
  - Scranton, Pennsylvania, Forenede Stater, 18508
    - Hematology and Oncology Associates of North East Pennsylvania
  - Sellersville, Pennsylvania, Forenede Stater, 18960
    - Grand View Hospital
  - State College, Pennsylvania, Forenede Stater, 16801
    - Geisinger Medical Group
  - State College, Pennsylvania, Forenede Stater, 16803
    - Mount Nittany Medical Center
  - Upland, Pennsylvania, Forenede Stater, 19013
    - Associates In Hematology Oncology PC-Upland
  - West Reading, Pennsylvania, Forenede Stater, 19611
    - Reading Hospital
  - Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
    - Geisinger Wyoming Valley/Henry Cancer Center
  - Wilkes-Barre, Pennsylvania, Forenede Stater, 18765
    - Geisinger South Wilkes-Barre
  - Williamsport, Pennsylvania, Forenede Stater, 17701
    - UPMC Susquehanna
  - Wynnewood, Pennsylvania, Forenede Stater, 19096
    - Lankenau Medical Center
  - Wynnewood, Pennsylvania, Forenede Stater, 19096
    - Main Line Health NCORP
  - York, Pennsylvania, Forenede Stater, 17403
    - WellSpan Health-York Hospital
- Rhode Island
  - Cranston, Rhode Island, Forenede Stater, 02920
    - Hematology and Oncology Associates of Rhode Island Inc
  - Pawtucket, Rhode Island, Forenede Stater, 02860
    - Memorial Hospital of Rhode Island
  - Providence, Rhode Island, Forenede Stater, 02903
    - Rhode Island Hospital
  - Providence, Rhode Island, Forenede Stater, 02906
    - Miriam Hospital
  - Warwick, Rhode Island, Forenede Stater, 02886
    - Kent Hospital
- South Carolina
  - Anderson, South Carolina, Forenede Stater, 29621
    - AnMed Health Cancer Center
  - Anderson, South Carolina, Forenede Stater, 29621
    - AnMed Health Hospital
  - Boiling Springs, South Carolina, Forenede Stater, 29316
    - Prisma Health Cancer Institute - Spartanburg
  - Charleston, South Carolina, Forenede Stater, 29425
    - Medical University of South Carolina
  - Charleston, South Carolina, Forenede Stater, 29401
    - Roper Hospital
  - Easley, South Carolina, Forenede Stater, 29640
    - Prisma Health Cancer Institute - Easley
  - Florence, South Carolina, Forenede Stater, 29506
    - McLeod Regional Medical Center
  - Greenville, South Carolina, Forenede Stater, 29605
    - Prisma Health Cancer Institute - Faris
  - Greenville, South Carolina, Forenede Stater, 29615
    - Prisma Health Cancer Institute - Eastside
  - Greenville, South Carolina, Forenede Stater, 29605
    - Prisma Health Cancer Institute - Butternut
  - Greenville, South Carolina, Forenede Stater, 29601
    - Saint Francis Hospital
  - Greenville, South Carolina, Forenede Stater, 29605
    - Prisma Health Greenville Memorial Hospital
  - Greenville, South Carolina, Forenede Stater, 29601
    - Greenville Health System Cancer Institute-Andrews
  - Greenwood, South Carolina, Forenede Stater, 29646
    - Self Regional Healthcare
  - Greer, South Carolina, Forenede Stater, 29650
    - Prisma Health Cancer Institute - Greer
  - Rock Hill, South Carolina, Forenede Stater, 29732
    - Levine Cancer Institute-Rock Hill
  - Seneca, South Carolina, Forenede Stater, 29672
    - Prisma Health Cancer Institute - Seneca
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - Spartanburg Medical Center
- South Dakota
  - Aberdeen, South Dakota, Forenede Stater, 57401
    - Avera Cancer Institute-Aberdeen
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Rapid City Regional Hospital
  - Sioux Falls, South Dakota, Forenede Stater, 57105
    - Avera Cancer Institute
  - Sioux Falls, South Dakota, Forenede Stater, 57117-5134
    - Sanford USD Medical Center - Sioux Falls
  - Sioux Falls, South Dakota, Forenede Stater, 57104
    - Sanford Cancer Center Oncology Clinic
  - Sioux Falls, South Dakota, Forenede Stater, 57105
    - Medical X-Ray Center
  - Sioux Falls, South Dakota, Forenede Stater, 57117-5045
    - Avera McKennan Hospital and University Health Center
- Tennessee
  - Bristol, Tennessee, Forenede Stater, 37620
    - Wellmont Medical Associates Oncology and Hematology-Bristol
  - Chattanooga, Tennessee, Forenede Stater, 37403
    - Erlanger Medical Center
  - Franklin, Tennessee, Forenede Stater, 37067
    - Vanderbilt-Ingram Cancer Center Cool Springs
  - Germantown, Tennessee, Forenede Stater, 38138
    - Jones Clinic
  - Jackson, Tennessee, Forenede Stater, 38301
    - Jackson-Madison County General Hospital
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Wellmont Holston Valley Hospital and Medical Center
  - Knoxville, Tennessee, Forenede Stater, 37916
    - Thompson Cancer Survival Center
  - Knoxville, Tennessee, Forenede Stater, 37920
    - University of Tennessee - Knoxville
  - Memphis, Tennessee, Forenede Stater, 38163
    - University of Tennessee Health Science Center
  - Nashville, Tennessee, Forenede Stater, 37232
    - Vanderbilt University/Ingram Cancer Center
  - Nashville, Tennessee, Forenede Stater, 37208
    - Meharry Medical College
  - Nashville, Tennessee, Forenede Stater, 37203
    - Nashville Oncology Associates PC
- Texas
  - Amarillo, Texas, Forenede Stater, 79106
    - The Don and Sybil Harrington Cancer Center
  - Dallas, Texas, Forenede Stater, 75235
    - Parkland Memorial Hospital
  - Dallas, Texas, Forenede Stater, 75390
    - UT Southwestern/Simmons Cancer Center-Dallas
  - Dallas, Texas, Forenede Stater, 75230
    - Medical City Dallas Hospital
  - Dallas, Texas, Forenede Stater, 75246
    - Baylor University Medical Center
  - Dallas, Texas, Forenede Stater, 75216
    - Dallas VA Medical Center
  - Dallas, Texas, Forenede Stater, 75390
    - Clements University Hospital
  - Dallas, Texas, Forenede Stater, 75231
    - Texas Health Presbyterian Hospital Dallas
  - Fort Sam Houston, Texas, Forenede Stater, 78234
    - Brooke Army Medical Center
  - Lackland Air Force Base, Texas, Forenede Stater, 78236
    - Wilford Hall Medical Center
  - Lubbock, Texas, Forenede Stater, 79430
    - Texas Tech University Health Sciences Center-Lubbock
  - San Antonio, Texas, Forenede Stater, 78229
    - University Hospital
  - San Antonio, Texas, Forenede Stater, 78229
    - University of Texas Health Science Center at San Antonio
  - San Antonio, Texas, Forenede Stater, 78229
    - Cancer Therapy and Research Center at The UT Health Science Center at San Antonio
  - San Antonio, Texas, Forenede Stater, 78229
    - Audie L Murphy VA Hospital
  - Temple, Texas, Forenede Stater, 76508
    - Scott and White Memorial Hospital
- Utah
  - Salt Lake City, Utah, Forenede Stater, 84112
    - Huntsman Cancer Institute/University of Utah
- Vermont
  - Bennington, Vermont, Forenede Stater, 05201
    - Southwestern Vermont Medical Center
  - Berlin, Vermont, Forenede Stater, 05602
    - Central Vermont Medical Center/National Life Cancer Treatment
  - Burlington, Vermont, Forenede Stater, 05405
    - University of Vermont and State Agricultural College
- Virginia
  - Charlottesville, Virginia, Forenede Stater, 22908
    - University of Virginia Cancer Center
  - Charlottesville, Virginia, Forenede Stater, 22901
    - Sentara Martha Jefferson Hospital
  - Danville, Virginia, Forenede Stater, 24541
    - Danville Regional Medical Center
  - Fredericksburg, Virginia, Forenede Stater, 22401
    - Fredericksburg Oncology Inc
  - Fredericksburg, Virginia, Forenede Stater, 22408
    - Hematology Oncology Associates of Fredericksburg Inc
  - Hampton, Virginia, Forenede Stater, 23666
    - Virginia Oncology Associates-Hampton
  - Lynchburg, Virginia, Forenede Stater, 24501
    - Centra Lynchburg Hematology-Oncology Clinic Inc
  - Martinsville, Virginia, Forenede Stater, 24115
    - Sovah Health Martinsville
  - Norton, Virginia, Forenede Stater, 24273
    - Southwest VA Regional Cancer Center
  - Richmond, Virginia, Forenede Stater, 23298
    - Virginia Commonwealth University/Massey Cancer Center
  - Richmond, Virginia, Forenede Stater, 23249
    - Hunter Holmes McGuire Veterans Administration Medical Center
- Washington
  - Anacortes, Washington, Forenede Stater, 98221
    - Cancer Care Center at Island Hospital
  - Auburn, Washington, Forenede Stater, 98001
    - MultiCare Auburn Medical Center
  - Bellevue, Washington, Forenede Stater, 98004
    - Overlake Medical Center
  - Bellingham, Washington, Forenede Stater, 98225
    - PeaceHealth Saint Joseph Medical Center
  - Bremerton, Washington, Forenede Stater, 98310
    - Harrison HealthPartners Hematology and Oncology-Bremerton
  - Burien, Washington, Forenede Stater, 98166
    - Highline Medical Center-Main Campus
  - Centralia, Washington, Forenede Stater, 98531
    - Providence Regional Cancer System-Centralia
  - Edmonds, Washington, Forenede Stater, 98026
    - Swedish Cancer Institute-Edmonds
  - Everett, Washington, Forenede Stater, 98201
    - Providence Regional Cancer Partnership
  - Federal Way, Washington, Forenede Stater, 98003
    - Saint Francis Hospital
  - Issaquah, Washington, Forenede Stater, 98029
    - Swedish Cancer Institute-Issaquah
  - Kennewick, Washington, Forenede Stater, 99336
    - Kadlec Clinic Hematology and Oncology
  - Kirkland, Washington, Forenede Stater, 98034
    - Seattle Cancer Care Alliance at EvergreenHealth
  - Kirkland, Washington, Forenede Stater, 98033
    - EvergreenHealth Medical Center
  - Lacey, Washington, Forenede Stater, 98503
    - Providence Regional Cancer System-Lacey
  - Lakewood, Washington, Forenede Stater, 98499
    - Saint Clare Hospital
  - Mount Vernon, Washington, Forenede Stater, 98274
    - Skagit Valley Hospital
  - Olympia, Washington, Forenede Stater, 98506-5166
    - Providence - Saint Peter Hospital
  - Port Angeles, Washington, Forenede Stater, 98362
    - Olympic Medical Center
  - Poulsbo, Washington, Forenede Stater, 98370
    - Harrison HealthPartners Hematology and Oncology-Poulsbo
  - Puyallup, Washington, Forenede Stater, 98372
    - MultiCare Good Samaritan Hospital
  - Renton, Washington, Forenede Stater, 98055
    - Valley Medical Center
  - Seattle, Washington, Forenede Stater, 98109
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forenede Stater, 98104
    - Harborview Medical Center
  - Seattle, Washington, Forenede Stater, 98101
    - Virginia Mason Medical Center
  - Seattle, Washington, Forenede Stater, 98122
    - Swedish Medical Center-First Hill
  - Seattle, Washington, Forenede Stater, 98195
    - University of Washington Medical Center - Montlake
  - Seattle, Washington, Forenede Stater, 98112
    - Kaiser Permanente Washington
  - Seattle, Washington, Forenede Stater, 98104
    - Minor and James Medical PLLC
  - Seattle, Washington, Forenede Stater, 98104
    - Pacific Medical Center-First Hill
  - Seattle, Washington, Forenede Stater, 98122
    - Pacific Cancer Research Consortium NCORP
  - Sedro-Woolley, Washington, Forenede Stater, 98284
    - PeaceHealth United General Medical Center
  - Spokane, Washington, Forenede Stater, 99218
    - Evergreen Hematology and Oncology PS
  - Spokane, Washington, Forenede Stater, 99202
    - Cancer Care Northwest - Spokane South
  - Spokane, Washington, Forenede Stater, 99220
    - Rockwood Clinic
  - Tacoma, Washington, Forenede Stater, 98431
    - Madigan Army Medical Center
  - Tacoma, Washington, Forenede Stater, 98405
    - MultiCare Tacoma General Hospital
  - Tacoma, Washington, Forenede Stater, 98405
    - MultiCare Allenmore Hospital
  - Tacoma, Washington, Forenede Stater, 98405
    - Northwest NCI Community Oncology Research Program
  - Tacoma, Washington, Forenede Stater, 98405
    - Saint Joseph Medical Center
  - Vancouver, Washington, Forenede Stater, 98686
    - Legacy Salmon Creek Hospital
  - Vancouver, Washington, Forenede Stater, 98664
    - PeaceHealth Southwest Medical Center
  - Vancouver, Washington, Forenede Stater, 98684
    - Compass Oncology Vancouver
  - Wenatchee, Washington, Forenede Stater, 98801
    - Wenatchee Valley Hospital and Clinics
- West Virginia
  - Charleston, West Virginia, Forenede Stater, 25304
    - West Virginia University Charleston Division
  - Huntington, West Virginia, Forenede Stater, 25701
    - Edwards Comprehensive Cancer Center
  - Huntington, West Virginia, Forenede Stater, 25702
    - Saint Mary's Medical Center
  - Morgantown, West Virginia, Forenede Stater, 26506
    - West Virginia University Healthcare
  - Wheeling, West Virginia, Forenede Stater, 26003
    - Wheeling Hospital/Schiffler Cancer Center
- Wisconsin
  - Appleton, Wisconsin, Forenede Stater, 54911
    - ThedaCare Regional Cancer Center
  - Burlington, Wisconsin, Forenede Stater, 53105
    - Aurora Cancer Care-Southern Lakes VLCC
  - Chippewa Falls, Wisconsin, Forenede Stater, 54729
    - Marshfield Clinic-Chippewa Center
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - HSHS Sacred Heart Hospital
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - Mayo Clinic Health System-Eau Claire Clinic
  - Eau Claire, Wisconsin, Forenede Stater, 54703
    - Mayo Clinic Health System Eau Claire Hospital-Luther Campus
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - Marshfield Clinic Cancer Center at Sacred Heart
  - Fond Du Lac, Wisconsin, Forenede Stater, 54935
    - Saint Agnes Hospital/Agnesian Cancer Center
  - Franklin, Wisconsin, Forenede Stater, 53132
    - Aurora Cancer Care-Franklin
  - Germantown, Wisconsin, Forenede Stater, 53022
    - Aurora Health Care Germantown Health Center
  - Glendale, Wisconsin, Forenede Stater, 53212
    - Aurora Cancer Care-Glendale
  - Green Bay, Wisconsin, Forenede Stater, 54311
    - Aurora BayCare Medical Center
  - Green Bay, Wisconsin, Forenede Stater, 54301
    - Saint Vincent Hospital Cancer Center Green Bay
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - Saint Vincent Hospital Cancer Center at Saint Mary's
  - Green Bay, Wisconsin, Forenede Stater, 54301
    - Bellin Memorial Hospital
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - Green Bay Oncology Limited at Saint Mary's Hospital
  - Green Bay, Wisconsin, Forenede Stater, 54301-3526
    - Green Bay Oncology at Saint Vincent Hospital
  - Janesville, Wisconsin, Forenede Stater, 53548
    - Mercyhealth Hospital and Cancer Center - Janesville
  - Johnson Creek, Wisconsin, Forenede Stater, 53038
    - UW Cancer Center Johnson Creek
  - Kenosha, Wisconsin, Forenede Stater, 53142
    - Aurora Cancer Care-Kenosha South
  - La Crosse, Wisconsin, Forenede Stater, 54601
    - Gundersen Lutheran Medical Center
  - La Crosse, Wisconsin, Forenede Stater, 54601
    - Mayo Clinic Health System-Franciscan Healthcare
  - Madison, Wisconsin, Forenede Stater, 53717
    - Dean Hematology and Oncology Clinic
  - Madison, Wisconsin, Forenede Stater, 53792
    - University of Wisconsin Carbone Cancer Center
  - Manitowoc, Wisconsin, Forenede Stater, 54221
    - Holy Family Memorial Hospital
  - Marinette, Wisconsin, Forenede Stater, 54143
    - Aurora Bay Area Medical Group-Marinette
  - Marinette, Wisconsin, Forenede Stater, 54143
    - Bay Area Medical Center
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - Marshfield Medical Center-Marshfield
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - Marshfield Medical Center
  - Mequon, Wisconsin, Forenede Stater, 53097
    - Ascension Columbia Saint Mary's Hospital Ozaukee
  - Milwaukee, Wisconsin, Forenede Stater, 53226
    - Medical College of Wisconsin
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Aurora Saint Luke's Medical Center
  - Milwaukee, Wisconsin, Forenede Stater, 53233
    - Aurora Sinai Medical Center
  - Milwaukee, Wisconsin, Forenede Stater, 53210
    - Ascension Southeast Wisconsin Hospital - Saint Joseph Campus
  - Milwaukee, Wisconsin, Forenede Stater, 53211
    - Ascension Columbia Saint Mary's Hospital - Milwaukee
  - Minocqua, Wisconsin, Forenede Stater, 54548
    - Marshfield Clinic-Minocqua Center
  - New Richmond, Wisconsin, Forenede Stater, 54017
    - Cancer Center of Western Wisconsin
  - Oconto Falls, Wisconsin, Forenede Stater, 54154
    - Saint Vincent Hospital Cancer Center at Oconto Falls
  - Oshkosh, Wisconsin, Forenede Stater, 54904
    - Vince Lombardi Cancer Clinic - Oshkosh
  - Racine, Wisconsin, Forenede Stater, 53406
    - Aurora Cancer Care-Racine
  - Racine, Wisconsin, Forenede Stater, 53405
    - Ascension All Saints Hospital
  - Rhinelander, Wisconsin, Forenede Stater, 54501
    - Ascension Saint Mary's Hospital
  - Rice Lake, Wisconsin, Forenede Stater, 54868
    - Marshfield Medical Center-Rice Lake
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - Vince Lombardi Cancer Clinic-Sheboygan
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - HSHS Saint Nicholas Hospital
  - Stevens Point, Wisconsin, Forenede Stater, 54481
    - Ascension Saint Michael's Hospital
  - Sturgeon Bay, Wisconsin, Forenede Stater, 54235
    - Green Bay Oncology - Sturgeon Bay
  - Summit, Wisconsin, Forenede Stater, 53066
    - Aurora Medical Center in Summit
  - Two Rivers, Wisconsin, Forenede Stater, 54241
    - Vince Lombardi Cancer Clinic-Two Rivers
  - Waukesha, Wisconsin, Forenede Stater, 53188
    - Aurora Cancer Care-Waukesha
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Aspirus Regional Cancer Center
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Marshfield Clinic-Wausau Center
  - Wauwatosa, Wisconsin, Forenede Stater, 53226
    - Aurora Cancer Care-Milwaukee West
  - Weston, Wisconsin, Forenede Stater, 54476
    - Marshfield Medical Center - Weston
  - Weston, Wisconsin, Forenede Stater, 54476
    - Diagnostic and Treatment Center
  - Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
    - Aspirus Cancer Care - Wisconsin Rapids
  - Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
    - Marshfield Clinic - Wisconsin Rapids Center
- Wyoming
  - Casper, Wyoming, Forenede Stater, 82609
    - Rocky Mountain Oncology
  - Sheridan, Wyoming, Forenede Stater, 82801
    - Welch Cancer Center
Irland
- - Cork, Irland
    - Cork University Hospital
  - Dublin, Irland, 8
    - Saint James Hospital
- Co Dublin
  - Dublin, Co Dublin, Irland, 24
    - Tallaght University Hospital
  - Dublin, Co Dublin, Irland, 4
    - Saint Vincent's University Hospital
  - Dublin, Co Dublin, Irland, 7
    - Mater Misericordiae University Hospital
  - Dublin, Co Dublin, Irland, 7
    - Mater Private Hospital
  - Dublin, Co Dublin, Irland, 9
    - Beaumont Hospital
- Co Galway
  - Galway, Co Galway, Irland
    - University College Hospital Galway
- Co Limerick
  - Limerick, Co Limerick, Irland, 9
    - Mid-Western Regional Hospital
- Co Waterford
  - Waterford, Co Waterford, Irland, 9
    - University Hospital Waterford
Peru
- - Lima, Peru, Lima 34
    - Instituto Nacional de Enfermedades Neoplasicas
Sydafrika
- - Pretoria, Sydafrika, 0002
    - University of Pretoria

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Beskrivelse

Inklusionskriterier:

For at være berettiget til dette forsøg skal patienter have gennemgået fuldstændig resektion af deres ikke-småcellede lungekræft (NSCLC) [stadium IB (>= 4 cm)] - [IIIA (T2-3N0, T1-3N1, T1- 3N2] før tilmelding; accepterede typer af resektion vil bestå af lobektomi, ærmelobektomi, bi-lobektomi eller pneumonektomi; resektioner ved segmentektomi eller kileresektion vil ikke blive accepteret; mediastinal lymfeknudeprøvetagning på specificerede niveauer er påkrævet præoperativt) (mediastinoskopi) eller intraoperativt (niveau 7 og 4 for højresidede tumorer eller niveau 7 og 5 og/eller 6 for venstresidede tumorer)
Patienterne skal være mindst 6 uger (42 dage) og ikke mere end 12 uger (84 dage) efter thorakotomi på randomiseringstidspunktet og skal være tilstrækkeligt restitueret efter operationen
Eastern Cooperative Oncology Group (ECOG) præstationsstatus 0 eller 1
Patienter må ikke have modtaget følgende:
- Forudgående systemisk kemoterapi til enhver tid; methotrexat (MTX) givet i lave doser til ikke-maligne tilstande med sidste dosis mindst 2 uger før registreringsdatoen vil være tilladt; andre lavdosis kemoterapeutika til ikke-maligne tilstande vil blive overvejet, men undersøgelse af studielederen er påkrævet
- Hormonal cancerbehandling eller strålebehandling som forudgående cancerbehandling inden for 5 år efter randomisering; (tidligere operation, biologisk terapi, hormonbehandling eller strålebehandling for en malignitet over 5 år før indskrivning, som nu anses for helbredt, er acceptabel)
Patienter må ikke have nogen anamnese med kræft inden for 5 år fra randomisering, med undtagelse af in-situ carcinom i livmoderhalsen eller fuldstændig resekeret ikke-melanom hudkræft
Absolut neutrofiltal (ANC) >= 1500 mm^3
Blodplader >= 100.000/mm^3
Protrombintid/internationalt normaliseret forhold (INR) =< 1,5
- Eller, hvis patienten er på terapeutisk antikoagulering, protrombintid/INR =< 3,0
Partiel tromboplastintid (PTT) =< institutionel øvre normalgrænse (ULN) ELLER, hvis patienten er på terapeutisk antikoagulering, skal PTT være =< 1,5 x ULN
Total bilirubin =< 1,5 mg/dL
Serumglutamin-oxaloeddikesyretransaminase (SGOT) (aspartataminotransferase [AST]) < 5 x øvre normalgrænse (ULN)
Serum glutamat pyruvat transaminase (SGPT) (alanin aminotransferase [ALT]) < 5 x øvre normalgrænse (ULN)
Serumkreatinin =< 1,5 x institutionel øvre normalgrænse (ULN)
Urinprotein bør screenes ved urinanalyse for urinproteinkreatinin (UPC) ratio; for UPC-forhold > 0,5 skal der opnås 24-timers urinprotein, og niveauet skal være < 1000 mg (1 g) for patientindskrivning
Patienter med en kendt anamnese med myokardieinfarkt eller andre tegn på arteriel trombotisk sygdom (angina) vil kun få adgang til undersøgelse, hvis de ikke har haft tegn på aktiv sygdom i mindst 12 måneder før randomisering
Patienter med nogen historie med cerebral vaskulær ulykke (CVA) eller forbigående iskæmisk anfald (TIA) vil ikke være tilladt i forsøg
Kvinder må ikke være gravide eller ammende
- Alle kvinder i den fødedygtige alder skal have en blod- eller urinprøve inden for 2 uger før randomisering for at udelukke graviditet
Både fertile mænd og kvinder skal acceptere at bruge passende præventionsforanstaltninger under undersøgelsesbehandlingen og i mindst 6 måneder efter afslutningen af bevacizumab
Patienter må ikke have nogen klinisk signifikant igangværende, aktiv eller alvorlig infektion, symptomatisk eller ukontrolleret kongestiv hjertesvigt, symptomatisk eller ukontrolleret hjertearytmi eller nogen anden medicinsk tilstand eller psykiatrisk sygdom/sociale situationer, der ville begrænse overholdelse af undersøgelseskrav
Patienter må ikke have nogen historie med blødende diatese eller koagulopati
Alle patienter skal have et dokumenteret blodtryk (BP) med systolisk =< 150 og diastolisk =< 90 inden for 28 dage efter registrering; patienter med kendt hypertension skal have et stabilt regime med antihypertensiv behandling
Patienter, der modtager daglig behandling med aspirin eller ikke-steroide antiinflammatoriske midler (NSAIDS) er berettigede; behandling med dipyridamol (Persantine), ticlopin (Ticlid), clopidogrel (Plavix) og/eller cilostazol (Pletal) er ikke tilladt; patienter skal være holdt op med at tage nogen af disse midler mindst 7 dage før randomisering
Patienter må ikke have alvorligt ikke-helende sår, mavesår, knoglebrud eller have gennemgået et større kirurgisk indgreb, åben biopsi eller betydelig traumatisk skade inden for 28 dage før randomisering ELLER kernebiopsi inden for 7 dage før randomisering
Patienter må ikke have en historie med abdominal fistel, gastrointestinal perforation eller intraabdominal absces inden for 28 dage før randomisering
Patienter må ikke have nogen forventede større kirurgiske indgreb i løbet af undersøgelsen
Patienter må ikke have kendt overfølsomhed over for ovariecelleprodukter fra kinesisk hamster eller andre rekombinante humane antistoffer
Patienter kan være på et stabilt regime med terapeutisk antikoagulering eller kan modtage profylaktisk antikoagulering af venøse adgangsanordninger, forudsat at koagulationsundersøgelser opfylder adgangskriterierne ovenfor; der skal udvises forsigtighed for patienter, der har behov for antikoagulering, inklusive behandling med lavdosis heparin eller lavmolekylært heparin til dyb venetrombose (DVT) profylakse under undersøgelsen
Patienter med igangværende postoperativ hæmoptyse (defineret som lyserødt blod på 1/2 teskefuld eller mere) er ikke kvalificerede; patienter med præoperativ hæmoptyse, der er forsvundet postoperativt, er berettigede
Patienter, der vil modtage pemetrexed (pemetrexed dinatrium)/cisplatin-behandling, skal også opfylde følgende kriterier:
- Patienter tildelt pemetrexed/cisplatin-behandling må IKKE have pladecellehistologi
- Beregnet kreatininclearance skal opnås inden for 2 uger efter randomisering, og beregnet kreatininclearance (CrCl) skal være >= 45 ml/min ved brug af standard Cockcroft og Gault-formlen eller den målte glomerulære filtrationshastighed (GFR) ved hjælp af den passende radioaktivt mærkede metode ([ 51]chrom-mærket ethylendiamintetraeddikesyre [51-CrEDTA] eller technetium 99m diethylentriamin-pentaeddikesyre [Tc99m-DTPA]) skal bruges til at beregne CrCl

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Ingen (Åben etiket)

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Aktiv komparator: Arm I (kemoterapi) Patienterne modtager en af følgende. For alle gentages behandlingen hver 21. dag i op til 4 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet. REGI 1: Vinorelbineditartrat 30 mg/m2 IV på dag 1 og 8, cisplatin 75 mg/m2 IV over 60 minutter på dag 1 REGIMEN 2: Docetaxel 75 mg/m2 IV og cisplastin 75 mg/m2 IV på dag 1 REGIMEN 3: Gemcitabinhydrochlorid 1200 mg/m2 IV på dag 1 og 8, cisplatin 75 mg/m2 IV på dag 1 REGIMEN 4 (kun ikke-pladeepitelhistologi): Pemetrexed dinatrium 500 mg/m2 IV og cisplatin 75 mg/m2 IV på dag 1	Andet: Laboratoriebiomarkøranalyse Korrelative undersøgelser Andet: Spørgeskemaadministration Hjælpestudier Medicin: Cisplatin Givet IV Andre navne: CDDP Cis-diammindichloridoplatin Cismaplat Cisplatin Neoplatin Platinol Abiplatin Blastolem Briplatin Cis-diammin-dichlorplatin Cis-diammindichlor platin (II) Cis-diamindichlorplatin Cis-dichloramin Platin (II) Cis-platinøst diamin dichlorid Cis-platin Cis-platin II Cis-platin II diamin dichlorid Cisplatina Cisplatyl Citoplatino Citosin Cysplatyna DDP Lederplatin Metaplatin Peyrones klorid Peyrones salt Placis Plastistil Platamin Platiblastin Platiblastin-S Platinex Platinol-AQ Platinol-AQ VHA Plus Platinoxan Platin Platindiaminodichlorid Platiran Platistin Platosin Medicin: Docetaxel Givet IV Andre navne: Taxotere Docecad RP56976 Taxotere injektionskoncentrat RP 56976 Medicin: Pemetrexed dinatrium Givet IV Andre navne: Alimta LY231514 N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutaminsyre dinatriumsalt Almita Medicin: Gemcitabinhydrochlorid Givet IV Andre navne: Gemzar dFdCyd Difluordeoxycytidin hydrochlorid Gemcitabin HCI LY-188011 LY188011 Medicin: Vinorelbin tartrat Givet IV Andre navne: Navlebine Eunades NVB Biovelbin KW-2307 Navelbine Ditartrat Vinorelbin-ditartrat
Eksperimentel: Arm II (kemoterapi, bevacizumab) Patienterne får kemoterapi som i arm I. Patienterne får også bevacizumab IV over 30-90 minutter på dag 1. Behandling med bevacizumab gentages hver 21. dag i op til 1 år.	Andet: Laboratoriebiomarkøranalyse Korrelative undersøgelser Andet: Spørgeskemaadministration Hjælpestudier Medicin: Cisplatin Givet IV Andre navne: CDDP Cis-diammindichloridoplatin Cismaplat Cisplatin Neoplatin Platinol Abiplatin Blastolem Briplatin Cis-diammin-dichlorplatin Cis-diammindichlor platin (II) Cis-diamindichlorplatin Cis-dichloramin Platin (II) Cis-platinøst diamin dichlorid Cis-platin Cis-platin II Cis-platin II diamin dichlorid Cisplatina Cisplatyl Citoplatino Citosin Cysplatyna DDP Lederplatin Metaplatin Peyrones klorid Peyrones salt Placis Plastistil Platamin Platiblastin Platiblastin-S Platinex Platinol-AQ Platinol-AQ VHA Plus Platinoxan Platin Platindiaminodichlorid Platiran Platistin Platosin Medicin: Docetaxel Givet IV Andre navne: Taxotere Docecad RP56976 Taxotere injektionskoncentrat RP 56976 Medicin: Pemetrexed dinatrium Givet IV Andre navne: Alimta LY231514 N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutaminsyre dinatriumsalt Almita Medicin: Gemcitabinhydrochlorid Givet IV Andre navne: Gemzar dFdCyd Difluordeoxycytidin hydrochlorid Gemcitabin HCI LY-188011 LY188011 Biologisk: Bevacizumab Givet IV Andre navne: Avastin ABP 215 Anti-VEGF Anti-VEGF humaniseret monoklonalt antistof Anti-VEGF monoklonalt antistof SIBP04 Anti-VEGF rhuMAb Bevacizumab awwb Bevacizumab Biosimilar ABP 215 Bevacizumab Biosimilar BEVZ92 Bevacizumab Biosimilar BI 695502 Bevacizumab Biosimilar CBT 124 Bevacizumab Biosimilar CT-P16 Bevacizumab Biosimilar FKB238 Bevacizumab Biosimilar GB-222 Bevacizumab Biosimilar HD204 Bevacizumab Biosimilar HLX04 Bevacizumab Biosimilar IBI305 Bevacizumab Biosimilar LY01008 Bevacizumab Biosimilar MIL60 Bevacizumab Biosimilar Mvasi Bevacizumab Biosimilar MYL-1402O Bevacizumab Biosimilar QL 1101 Bevacizumab Biosimilar RPH-001 Bevacizumab Biosimilar SCT501 Bevacizumab Biosimilar Zirabev Bevacizumab-awwb Bevacizumab-bvzr BP102 BP102 Biosimilar HD204 Immunoglobulin G1 (human-mus monoklonal rhuMab-VEGF gammakæde anti-human vaskulær endotelvækstfaktor), disulfid med human-mus monoklonal rhuMab-VEGF let kæde, dimer Mvasi MYL-1402O Rekombinant humaniseret anti-VEGF monoklonalt antistof rhuMab-VEGF SCT501 SIBP 04 SIBP-04 SIBP04 Zirabev QL1101 Bevacizumab Biosimilar QL1101 BAT1706 BAT 1706 BAT-1706 BAT1706 Biosimilar Bevacizumab Biosimilar BAT1706 Bevacizumab-adcd CT-P16 Vegzelma Medicin: Vinorelbin tartrat Givet IV Andre navne: Navlebine Eunades NVB Biovelbin KW-2307 Navelbine Ditartrat Vinorelbin-ditartrat

Deltagergruppe / Arm

Intervention / Behandling

Aktiv komparator: Arm I (kemoterapi)

Patienterne modtager en af følgende. For alle gentages behandlingen hver 21. dag i op til 4 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet.

REGI 1: Vinorelbineditartrat 30 mg/m2 IV på dag 1 og 8, cisplatin 75 mg/m2 IV over 60 minutter på dag 1 REGIMEN 2: Docetaxel 75 mg/m2 IV og cisplastin 75 mg/m2 IV på dag 1 REGIMEN 3: Gemcitabinhydrochlorid 1200 mg/m2 IV på dag 1 og 8, cisplatin 75 mg/m2 IV på dag 1 REGIMEN 4 (kun ikke-pladeepitelhistologi): Pemetrexed dinatrium 500 mg/m2 IV og cisplatin 75 mg/m2 IV på dag 1

Andet: Laboratoriebiomarkøranalyse

Korrelative undersøgelser

Andet: Spørgeskemaadministration

Hjælpestudier

Medicin: Cisplatin

Givet IV

Andre navne:

CDDP
Cis-diammindichloridoplatin
Cismaplat
Cisplatin
Neoplatin
Platinol
Abiplatin
Blastolem
Briplatin
Cis-diammin-dichlorplatin
Cis-diammindichlor platin (II)
Cis-diamindichlorplatin
Cis-dichloramin Platin (II)
Cis-platinøst diamin dichlorid
Cis-platin
Cis-platin II
Cis-platin II diamin dichlorid
Cisplatina
Cisplatyl
Citoplatino
Citosin
Cysplatyna
DDP
Lederplatin
Metaplatin
Peyrones klorid
Peyrones salt
Placis
Plastistil
Platamin
Platiblastin
Platiblastin-S
Platinex
Platinol-AQ
Platinol-AQ VHA Plus
Platinoxan
Platin
Platindiaminodichlorid
Platiran
Platistin
Platosin

Medicin: Docetaxel

Givet IV

Andre navne:

Taxotere
Docecad
RP56976
Taxotere injektionskoncentrat
RP 56976

Medicin: Pemetrexed dinatrium

Givet IV

Andre navne:

Alimta
LY231514
N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutaminsyre dinatriumsalt
Almita

Medicin: Gemcitabinhydrochlorid

Givet IV

Andre navne:

Gemzar
dFdCyd
Difluordeoxycytidin hydrochlorid
Gemcitabin HCI
LY-188011
LY188011

Medicin: Vinorelbin tartrat

Givet IV

Andre navne:

Navlebine
Eunades
NVB
Biovelbin
KW-2307
Navelbine Ditartrat
Vinorelbin-ditartrat

Eksperimentel: Arm II (kemoterapi, bevacizumab)

Patienterne får kemoterapi som i arm I. Patienterne får også bevacizumab IV over 30-90 minutter på dag 1. Behandling med bevacizumab gentages hver 21. dag i op til 1 år.

Andet: Laboratoriebiomarkøranalyse

Korrelative undersøgelser

Andet: Spørgeskemaadministration

Hjælpestudier

Medicin: Cisplatin

Givet IV

Andre navne:

CDDP
Cis-diammindichloridoplatin
Cismaplat
Cisplatin
Neoplatin
Platinol
Abiplatin
Blastolem
Briplatin
Cis-diammin-dichlorplatin
Cis-diammindichlor platin (II)
Cis-diamindichlorplatin
Cis-dichloramin Platin (II)
Cis-platinøst diamin dichlorid
Cis-platin
Cis-platin II
Cis-platin II diamin dichlorid
Cisplatina
Cisplatyl
Citoplatino
Citosin
Cysplatyna
DDP
Lederplatin
Metaplatin
Peyrones klorid
Peyrones salt
Placis
Plastistil
Platamin
Platiblastin
Platiblastin-S
Platinex
Platinol-AQ
Platinol-AQ VHA Plus
Platinoxan
Platin
Platindiaminodichlorid
Platiran
Platistin
Platosin

Medicin: Docetaxel

Givet IV

Andre navne:

Taxotere
Docecad
RP56976
Taxotere injektionskoncentrat
RP 56976

Medicin: Pemetrexed dinatrium

Givet IV

Andre navne:

Alimta
LY231514
N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutaminsyre dinatriumsalt
Almita

Medicin: Gemcitabinhydrochlorid

Givet IV

Andre navne:

Gemzar
dFdCyd
Difluordeoxycytidin hydrochlorid
Gemcitabin HCI
LY-188011
LY188011

Biologisk: Bevacizumab

Givet IV

Andre navne:

Avastin
ABP 215
Anti-VEGF
Anti-VEGF humaniseret monoklonalt antistof
Anti-VEGF monoklonalt antistof SIBP04
Anti-VEGF rhuMAb
Bevacizumab awwb
Bevacizumab Biosimilar ABP 215
Bevacizumab Biosimilar BEVZ92
Bevacizumab Biosimilar BI 695502
Bevacizumab Biosimilar CBT 124
Bevacizumab Biosimilar CT-P16
Bevacizumab Biosimilar FKB238
Bevacizumab Biosimilar GB-222
Bevacizumab Biosimilar HD204
Bevacizumab Biosimilar HLX04
Bevacizumab Biosimilar IBI305
Bevacizumab Biosimilar LY01008
Bevacizumab Biosimilar MIL60
Bevacizumab Biosimilar Mvasi
Bevacizumab Biosimilar MYL-1402O
Bevacizumab Biosimilar QL 1101
Bevacizumab Biosimilar RPH-001
Bevacizumab Biosimilar SCT501
Bevacizumab Biosimilar Zirabev
Bevacizumab-awwb
Bevacizumab-bvzr
BP102
BP102 Biosimilar
HD204
Immunoglobulin G1 (human-mus monoklonal rhuMab-VEGF gammakæde anti-human vaskulær endotelvækstfaktor), disulfid med human-mus monoklonal rhuMab-VEGF let kæde, dimer
Mvasi
MYL-1402O
Rekombinant humaniseret anti-VEGF monoklonalt antistof
rhuMab-VEGF
SCT501
SIBP 04
SIBP-04
SIBP04
Zirabev
QL1101
Bevacizumab Biosimilar QL1101
BAT1706
BAT 1706
BAT-1706
BAT1706 Biosimilar
Bevacizumab Biosimilar BAT1706
Bevacizumab-adcd
CT-P16
Vegzelma

Medicin: Vinorelbin tartrat

Givet IV

Andre navne:

Navlebine
Eunades
NVB
Biovelbin
KW-2307
Navelbine Ditartrat
Vinorelbin-ditartrat

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Samlet overlevelse Tidsramme: Fra registrering til død, op til 10 år	Samlet overlevelse (OS) blev defineret som tiden fra randomisering til død uanset årsag, og patienter, som man troede var i live på tidspunktet for den endelige analyse, blev censureret på den sidste kontaktdato. Undersøgelsen nåede ikke sit primære endepunkt.	Fra registrering til død, op til 10 år

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Sygdomsfri overlevelse Tidsramme: Fra registrering til død, op til 10 år	Sygdomsfri overlevelse (DFS) blev defineret som tiden fra randomisering til en hændelse. Hændelser omfatter sygdomstilbagefald, ny primær lungekræft, sekundær primære eller død, alt efter hvad der indtrådte først; det skal dog bemærkes, at patienter med nye primære sygdomme på andre ikke-lungesteder bør have fortsat opfølgning for tilbagefald af den oprindelige cancer. Patienter, der ikke har haft en hændelse rapporteret ved analyse, blev censureret på deres sidste dato for sygdomsvurdering.	Fra registrering til død, op til 10 år

Andre resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Toksicitetsrater vurderet af National Cancer Institute Common Terminology Criteria for Adverse Events Version 4.0 Tidsramme: Op til 1 år efter behandling	Hvis forskellen i frekvensen af en bestemt kategori af toksiciteter mellem de 2 arme (N=750 pr. arm) er mindst 5 % (4 % vs. 9 %), kan 96 % effekt opnås under antagelse af et signifikansniveau på 5 % (tosidet Chi Square test), og at den lavere toksicitetsrate for en arm er 4 %. En forskel i frekvensen af grad 3-5 arterielle tromboemboliske hændelser og blødningshændelser vil blive overvåget og vurderet mellem behandlingsarmene.	Op til 1 år efter behandling
Udfør analyser af væv og blod for at etablere faktorer, der forudsiger kliniske resultater hos patienter, der modtager kemoterapi, med eller uden bevacizumab, for resekeret tidligt stadium af NSCLC. Tidsramme: Fra registrering til død, op til 10 år		Fra registrering til død, op til 10 år
For at bestemme, om rygestatus er forbundet med udfaldet for patienter med resektioneret stadium IB - IIIA NSCLC behandlet med kemoterapi med eller uden bevacizumab i adjuverende omgivelser. Tidsramme: Fra registrering til død, op til 10 år		Fra registrering til død, op til 10 år

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

National Cancer Institute (NCI)

Samarbejdspartnere

NCIC Clinical Trials Group

Cancer and Leukemia Group B

North Central Cancer Treatment Group

SWOG Cancer Research Network

Efterforskere

Ledende efterforsker: Heather A Wakelee, ECOG-ACRIN Cancer Research Group

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Wakelee HA, Dahlberg SE, Keller SM, Tester WJ, Gandara DR, Graziano SL, Adjei AA, Leighl NB, Aisner SC, Rothman JM, Patel JD, Sborov MD, McDermott SR, Perez-Soler R, Traynor AM, Butts C, Evans T, Shafqat A, Chapman AE, Kasbari SS, Horn L, Ramalingam SS, Schiller JH; ECOG-ACRIN. Adjuvant chemotherapy with or without bevacizumab in patients with resected non-small-cell lung cancer (E1505): an open-label, multicentre, randomised, phase 3 trial. Lancet Oncol. 2017 Dec;18(12):1610-1623. doi: 10.1016/S1470-2045(17)30691-5. Epub 2017 Nov 9.

Hjælpsomme links

Data Available: Select individual patient-level data from this trial can be requested from the NCTN/NCORP Data Archive.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

1. juni 2007

Primær færdiggørelse (Faktiske)

20. oktober 2015

Studieafslutning (Anslået)

16. oktober 2024

Datoer for studieregistrering

Først indsendt

10. maj 2006

Først indsendt, der opfyldte QC-kriterier

10. maj 2006

Først opslået (Anslået)

11. maj 2006

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

17. april 2024

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

16. april 2024

Sidst verificeret

1. april 2024

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

NCI-2009-00509 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
U10CA180820 (U.S. NIH-bevilling/kontrakt)
U10CA021115 (U.S. NIH-bevilling/kontrakt)
09-0404
E1505 (Anden identifikator: CTEP)
CDR0000475774
ECOG-E1505

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Laboratoriebiomarkøranalyse

Liao Jian An

Rekruttering

Meridianenergiændringer hos patienter med hoved- og nakkekræft efter kemoterapi eller strålebehandling

Hoved- og halskræft

Taiwan
Progenity, Inc.

Afsluttet

Udvidet ikke-invasiv genomisk medicinsk vurdering: Enigma-undersøgelsen

Downs syndrom | Aneuploidi | DiGeorges syndrom | Turners syndrom | Klinefelters syndrom | Kromosom sletning | Edwards syndrom | Patau syndrom

Forenede Stater
Fondation Lenval

Trukket tilbage

Indflydelse af træthed på gangmønsteret hos patienter med cerebral parese.

Cerebral Parese

Frankrig
IRCCS Eugenio Medea

Rekruttering

Biomarkørers baner for tidlig intervention hos søskende til børn med autismespektrumforstyrrelse

Autismespektrumforstyrrelse | Tidlig indsats

Italien
Oregon Health and Science University
4DMedical

Tilmelding efter invitation

Ventilationsubalancer ved let til moderat kronisk obstruktiv lungesygdom (VAPOR)

Lungesygdomme | KOL | Luftvejssygdom | Dyspnø

Forenede Stater
IRCCS Eugenio Medea

Rekruttering

Bekræft præstationen i klinisk praksis af den fordybende Virtual Reality Platform GRAIL (Gait Real-time Analysis Interactive Lab)

Cerebral Parese | Erhvervet hjerneskade

Italien
Modarres Hospital

Afsluttet

Renal parenkymal kernenålbiopsi

Komplikationer | Billedstyret biopsi | Nyre Glomerulus

Iran, Islamisk Republik
Healthy.io Ltd.

Afsluttet

[Prøvning af enhed, der ikke er godkendt eller godkendt af U.S. FDA]

Albuminuri

Forenede Stater
Medwave Estudios Limitada
Asociación Chilena de Seguridad

Ukendt

Diagnostisk værdi af arbejdsbelastningsanalyseinstrument til at påvise erhvervsmæssige risici ved muskel- og skelettilstande i øvre lemmer (ACT-ACHS)

Erhvervsmæssig eksponering | Muskuloskeletal sygdom

Chile
Alcon Research

Afsluttet

Clareon IOL retrospektiv dataindsamling

Astigmatisme | Aphakia

Forenede Stater

Kemoterapi med eller uden Bevacizumab til behandling af patienter med trin IB, trin II eller trin IIIA Ikke-småcellet lungekræft, der blev fjernet ved kirurgi

Et fase III randomiseret forsøg med adjuverende kemoterapi med eller uden Bevacizumab til patienter med fuldstændigt resekeret stadium IB (≥ 4 cm) - IIIA ikke-småcellet lungekræft (NSCLC)

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Andre resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Samarbejdspartnere

Efterforskere

Publikationer og nyttige links

Generelle publikationer

Hjælpsomme links

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Faktiske)

Studieafslutning (Anslået)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Anslået)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Kliniske forsøg med Laboratoriebiomarkøranalyse

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Senegal

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer