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Prospektiv randomiseret evaluering af Celecoxib Integrated Safety vs Ibuprofen eller Naproxen (PRECISION)

1. marts 2021 opdateret af: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

En randomiseret, dobbeltblind, parallelgruppeundersøgelse af kardiovaskulær sikkerhed hos patienter med slidgigt eller leddegigt med eller i høj risiko for hjertekarsygdomme, der sammenligner Celecoxib med Naproxen og Ibuprofen

For at besvare spørgsmålet om den overordnede fordel: risiko for celecoxib sammenlignet med to, der oftest ordinerer traditionelle (ikke-selektive) ikke-steroide antiinflammatoriske lægemidler (NSAID'er) til behandling af gigtsmerter. Til dette formål vil patienter med slidgigt eller leddegigt med eller i risiko for at udvikle hjerte-kar-sygdom blive rekrutteret. Den kardiovaskulære, gastrointestinale og renale sikkerhed og symptomatiske fordele i hver behandlingsgruppe vil blive vurderet i overensstemmelse hermed.

Studieoversigt

Status

Afsluttet

Betingelser

Gigt, reumatoid

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

24081

Fase

Fase 4

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Australien
- New South Wales
  - Broadmeadow, New South Wales, Australien, 2292
    - Hunter Clinical Research
- Queensland
  - Auchenflower, Queensland, Australien, 4066
    - Wesley Medical Centre
  - Caboolture, Queensland, Australien, 4510
    - Australian Clinical Research Organisation
  - Cairns, Queensland, Australien, 4870
    - Rheumatology department
  - Kippa Ring, Queensland, Australien, 4021
    - AusTrials Pty Ltd
  - Milton, Queensland, Australien, 4064
    - Core Research Group
  - Sherwood, Queensland, Australien, 4075
    - AusTrials Pty Ltd
- Victoria
  - Clayton, Victoria, Australien, 3168
    - Monash Medical Centre, Department of Rheumatology
  - Heidelberg West, Victoria, Australien, 3081
    - Rheumatology department
  - Malvern East, Victoria, Australien, 3145
    - Emeritus Research
- Western Australia
  - Shenton Park, Western Australia, Australien, 6008
    - The Goatcher Clinical Research Unit
  - Victoria Park, Western Australia, Australien, 6979
    - The Colin Bayliss Research and Teaching Unit
Brasilien
- - Goiania-GO, Brasilien, 74110-020
    - Hospital Sao Salvador - Medicos Reunidos Ltda.
  - Marilia/SP, Brasilien, 17519-000
    - Ambulatorio de Especialidades Mario Covas
  - Porto Alegre, RS, Brasilien, 91350-200
    - Hospital Nossa Senhora da Conceicao
  - Recife - Pernambuco, Brasilien, 52679-420
    - Hospital das clínicas da UFPE
  - Rio de Janeiro, Brasilien, 20221-903
    - Hospital dos Servidores do Estado do Rio de Janeiro
  - Santo Andre, Brasilien, 09060-650
    - Faculdade de Medicina do ABC
- AL
  - Maceio, AL, Brasilien, 57021-500
    - CLINCOR - Clinica de Exames Cardiologicos e Ecografia S/C Ltda
  - Maceio, AL, Brasilien, 57052-580
    - Hospital do Coracao de Alagoas
- GO
  - Goiania, GO, Brasilien, 74110-120
    - CIP - Centro Internacional de Pesquisas
  - Goiania, GO, Brasilien, 74223-130
    - Via Medica - Centro Clinico
- MG
  - Juiz de Fora, MG, Brasilien, 36010-570
    - CMiP - Centro Mineiro de Pesquisa
- Minas Gerais
  - Belo Horizonte, Minas Gerais, Brasilien, 30150-260
    - Hopsital das Clinicas da Universidade Federal de Minas Gerais
- PR
  - Campina Grande do Sul, PR, Brasilien, 83430-000
    - Hospital e Maternidade Angelina Caron, Sala Pesquisa Clinica
  - Curitiba, PR, Brasilien, 80030-220
    - CEPEME-CERHFAC Centro de Estudos e Pesquisas Medicas
  - Curitiba, PR, Brasilien, 80060-240
    - Centro de Estudos do Hospital de Clínicas da UFPR
- RJ
  - Rio de Janeiro, RJ, Brasilien, 21941-913
    - Hospital Universitário Clementino Fraga Filho - UFRJ
  - Rio de Janeiro, RJ, Brasilien, 22271-100
    - CCBR Brasil Centro de Pesquisas e Analises Clinicas Ltda
  - Rio de Janeiro, RJ, Brasilien, 22411-001
    - Hospital Ipanema Plus
  - Rio de Janeiro, RJ, Brasilien, 22649-900
    - Clinica de Reumatologia do Centro Médico BarraShopping
- RS
  - Porto Alegre, RS, Brasilien, 90035-903
    - Centro de Pesquisa Clinica
  - Porto Alegre, RS, Brasilien, 90560-030
    - Associação Hospitalar Moinhos de Vento (AHMV) / CMIC
  - Porto Alegre, RS, Brasilien, 90610-000
    - Hospital São Lucas - Pontificia
- SAO Paulo
  - Campinas, SAO Paulo, Brasilien, 13059-740
    - Hospital e Maternidade Celso Pierro - PUC Campinas
- SE
  - Aracaju, SE, Brasilien, 49015-400
    - Centro de Ensino e Pesquisa Hospital Sao Lucas
- SP
  - Campinas, SP, Brasilien, 13059-740
    - PUC Campinas
  - Campinas, SP, Brasilien, 13083-888
    - Hospital das Clínicas da Unicamp
  - Marilia, SP, Brasilien, 17519-030
    - Hospital das Clinicas da Faculdade de Medicina de Marilia
  - Sao Jose do Rio Preto, SP, Brasilien, 15090-000
    - Hospital de Base - Fundacao Faculdade Regional de Medicina de São José do Rio Preto
  - Sao Paulo, SP, Brasilien, 01323-903
    - Hospital Alemao Oswaldo Cruz
  - Sao Paulo, SP, Brasilien, 04039-030
    - Setor de Lip., Arterosc. e BioVasc. - Disc. de Cardiologia
  - Sao Paulo, SP, Brasilien, 04266-010
    - CEPIC - Centro Paulista de Investigação Clínica
  - Sao Paulo, SP, Brasilien, 05437-010
    - IMA Brasil - Instituto de Medicina Avançada
  - São Paulo, SP, Brasilien, 01244-030
    - CPClin - Centro de Pesquisas Clínicas
Canada
- - Quebec, Canada, G1V 4G5
    - Institut Universitaire de cardiologie et de pneumologie de Quebec
  - Quebec, Canada, G1G 3Y8
    - Recherche Clinique Sigma, Inc.
- Alberta
  - Calgary, Alberta, Canada, T2X 3X7
    - South Calgary Medical Clinic - Sunpark Professional Center
  - Edmonton, Alberta, Canada, T5K 2A2
    - Allin Clinic
  - Edmonton, Alberta, Canada, T6K 4C1
    - Dr. MPJ Senaratne Professional Corporation
- British Columbia
  - Kelowna, British Columbia, Canada, V1Y 3G8
    - Medical Arts Health Research Group
  - Penticton, British Columbia, Canada, V2A 5C8
    - The Medical Arts Health Research Group
  - Surrey, British Columbia, Canada, V3S 2N6
    - Ocean West Research Clinic Inc.
  - Vancouver, British Columbia, Canada, V5Z 4E1
    - Prohealth Clinical Research Inc.
  - Victoria, British Columbia, Canada, V8P 5P6
    - Office of Dr. Milton F. Baker
  - West Vancouver, British Columbia, Canada, V7T 2Z3
    - The Medical Arts Health Research Group
- Manitoba
  - Winnipeg, Manitoba, Canada, R3A 1M3
    - Manitoba Clinic
  - Winnipeg, Manitoba, Canada, R2V 4W3
    - Rivergrove Medical Clinic
- New Brunswick
  - Moncton, New Brunswick, Canada, E1G 1A7
    - G.A. Research Associates Ltd/Ltee
  - Quispamis, New Brunswick, Canada, E2E 4J8
    - Eric N. Grant Professional Corporation
  - Saint John, New Brunswick, Canada, E2K 2T8
    - Office of Dr. Brian N. Craig
- Newfoundland and Labrador
  - Mount Pearl, Newfoundland and Labrador, Canada, A1N 1W7
    - Commonwealth Medical Clinic
  - Paradise, Newfoundland and Labrador, Canada, A1L 1C6
    - Paradise Medical Clinic
  - St. John's, Newfoundland and Labrador, Canada, A1A 3R5
    - White Hills Medical Clinic
  - St. John's, Newfoundland and Labrador, Canada, A1A 5E8
    - Nexus Clinic Research
  - St. John's, Newfoundland and Labrador, Canada, A1C 2H5
    - The Clinical Trials Centre
  - St. John's, Newfoundland and Labrador, Canada, A1E 2E2
    - Topsail Road Medical Clinic
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3K 0A4
    - MSHJ Research Associates, Inc.
  - Truro, Nova Scotia, Canada, B2N 1L2
    - Colchester Research Group
- Ontario
  - Brampton, Ontario, Canada, L6R 3A5
    - Office of Dr. Rohit Nagpal
  - Brampton, Ontario, Canada, L6T 3J1
    - Aggarwal and Associates Ltd.
  - Burlington, Ontario, Canada, L7M 4Y1
    - Aviva Clinical Trial Group Inc.
  - Corunna, Ontario, Canada, N0N 1G0
    - Corunna Medical Research Center
  - Fort Erie, Ontario, Canada, L2A 1Z3
    - C & L Research
  - Hamilton, Ontario, Canada, L8N 1Y2
    - Office of Dr. Jonathan D. Adachi
  - Kitchener, Ontario, Canada, N2E 4H9
    - Office of Dr. John Mutrie
  - Kitchener, Ontario, Canada, N2M 5N6
    - KW Musculoskeletal Research Inc.
  - London, Ontario, Canada, N5W 3C6
    - East London Medical Centre
  - London, Ontario, Canada, N5W 6A2
    - London East Medical Centre
  - London, Ontario, Canada, N5Y 5K7
    - Office of Dr. Gordon Schacter
  - London, Ontario, Canada, N6A 3H5
    - Office of Dr. William Blake Bowler
  - London, Ontario, Canada, N6A 5G6
    - Office of Dr. Robert G. Luton
  - Mississauga, Ontario, Canada, L4T 4J2
    - Malton Medical Centre
  - Newmarket, Ontario, Canada, L3Y 3R7
    - The Arthritis Program Research Group Inc.
  - Newmarket, Ontario, Canada, L3Y 5G8
    - SKDS Research Inc.
  - Niagara Falls, Ontario, Canada, L2E 7H1
    - Office of Dr. Azim M. Velji
  - Ottawa, Ontario, Canada, K1G 0Z3
    - AIM Health Group Trainyards Health and Wellness Centre
  - Sarnia, Ontario, Canada, N7T 4X3
    - London Road Diagnostic Clinic & Medical Center
  - Sarnia, Ontario, Canada, N7T 4X3
    - London Road Diagnostic Clinic & Medical Centre
  - Sudbury, Ontario, Canada, P3C 5K7
    - Office of Dr. Swaran K. Syan
  - Toronto, Ontario, Canada, M9W 4L6
    - Manna Research
  - Toronto, Ontario, Canada, M3M 3E5
    - Keele Medical Place
  - Toronto, Ontario, Canada, M4S 1Y2
    - Prime Health Clinical Research
  - Toronto, Ontario, Canada, M6A 3B5
    - Office of Dr. Ira Bernstein
  - Toronto, Ontario, Canada, M8V 3X8
    - Office of Dr. Subodh Kanani
  - Windsor, Ontario, Canada, N8X 5A6
    - Clinical Research and Arthritis Centre
  - Windsor, Ontario, Canada, N8W 1E6
    - North Walkerville Orthopaedic Associates
  - Windsor, Ontario, Canada, N8W 1E6
    - Research Office
- Quebec
  - Chicoutimi, Quebec, Canada, G7H 5H6
    - Centre De Sante Et De Services Sociaux De Chicoutimi
  - Chicoutimi, Quebec, Canada, G7H 7P2
    - ECOGENE-21 / Centre de sante et de services sociaux de Chicoutimi
  - Cowansville, Quebec, Canada, J2K 2X9
    - Clinique de Medicine Familiale de Cowansville
  - L'Ancienne-Lorette, Quebec, Canada, G2E 2X1
    - Centre de recherche clinique Adapra Inc.
  - Montreal, Quebec, Canada, H1L 2N9
    - Centre de Recherche Hochelaga/ Clinique Medicale Hochelaga
  - Montreal, Quebec, Canada, H3N 1S4
    - Recherche Medicale Appliquee Informatics (AMIR) Inc.
  - Pointe-Claire, Quebec, Canada, H9R 4S3
    - Kells Medical Research Group, Inc.
  - Quebec City, Quebec, Canada, G1H 7L3
    - Le Manoir de l'Atrium
  - Rosemere, Quebec, Canada, J7A 1K7
    - Clinique Services Sante Rosemere
  - Saint-Marc-des-Carrieres, Quebec, Canada, G0A 4B0
    - Centre Medical des Carrieres
  - St-Jerome, Quebec, Canada, J7Z 5T3
    - St-Jerome Medical Research Inc.
  - Trois-Rivieres, Quebec, Canada, G8Z 1Y2
    - Centre de Recherche Musculo-Squelettique
  - Westmount, Quebec, Canada, H3Z 2M6
    - Cardiology and Research
- Saskatchewan
  - Saskatoon, Saskatchewan, Canada, S7L 0Y7
    - Downtown Medical Specialists
Colombia
- - Cali, Colombia, 760032
    - Fundacion Valle del Lili
- Antioquia
  - Medellin, Antioquia, Colombia
    - Reumalab S.A.S.
  - Medellin, Antioquia, Colombia, 050034
    - Hospital Pablo Tobon Uribe - Unidad de Investigaciones
  - Medellin, Antioquia, Colombia
    - IPS Rodrigo Botero S.A.S.
- Cundinamarca
  - Bogota, Cundinamarca, Colombia
    - Fundacion Cardioinfantil
  - Bogota, Cundinamarca, Colombia
    - Clinica Colsanitas Sa
- Santander
  - Floridablanca, Santander, Colombia
    - Fundacion cardiovascular de Colombia
Costa Rica
- - Alajuela, Costa Rica
    - Centro Medico San Rafael
  - Cartago, Costa Rica, 30101
    - Centro de Reumatologia y Osteoporosis
  - Cartago, Costa Rica
    - Clínica Garzona
  - Heredia, Costa Rica
    - Clinica de Especialidades Medicas Drs. Saenz Castro
  - Heredia, Costa Rica
    - Clínica Monte Sión
  - Heredia, Costa Rica
    - Clínica San Antonio
  - San Jose, Costa Rica
    - Hospital Clínica Biblica
  - San Jose, Costa Rica
    - Centro Medico San Jose
  - San Jose, Costa Rica
    - Edificio Panda
  - San Jose, Costa Rica
    - Oficina Privada
- Cartago
  - La Union De Tres Rios, Cartago, Costa Rica, 30303
    - Clínica Vía San Juan
- San Jose
  - Desamparados Centro, San Jose, Costa Rica, 0000
    - Clínica San Agustín
  - Escazu, San Jose, Costa Rica
    - Hospital CIMA San Jose
  - Goicoechea, San Jose, Costa Rica
    - Hospital Hotel La Catolica
- San José
  - Moravia, San José, Costa Rica, 0000
    - Consultorio Privado Dr. Alberto Lainez Ventosilla
Filippinerne
- - Cebu City, Filippinerne, 6000
    - Chong Hua Hospital
  - Davao City, Filippinerne, 8000
    - Southern Philippines Medical Center
  - Manila, Filippinerne, 1003
    - Jose R. Reyes Memorial Medical Center
  - Manila, Filippinerne, 1014
    - Chinese General Hospital and Medical Center
  - Manila, Filippinerne, 1015
    - Hospital Research Unit, University of Santo Tomas Hospital
  - Quezon City, Filippinerne, 1102
    - St. Luke's Medical Center
- Batangas
  - Lipa City, Batangas, Filippinerne, 4217
    - Mary Mediatrix Medical Center
- Cavite
  - Dasmarinas, Cavite, Filippinerne, 4114
    - De La Salle Health Sciences Institute
Forenede Stater
- Alabama
  - Alabaster, Alabama, Forenede Stater, 35007
    - Carol M. Johnson MD, LLC
  - Bessemer, Alabama, Forenede Stater, 35022
    - Orthopaedics West
  - Birmingham, Alabama, Forenede Stater, 35235
    - Alabama Clinical Therapeutics, LLC
  - Birmingham, Alabama, Forenede Stater, 35216
    - Achieve Clinical Research, LLC
  - Birmingham, Alabama, Forenede Stater, 35209
    - Central Alabama Research
  - Birmingham, Alabama, Forenede Stater, 35211
    - Simon Williamson Clinic/Clinical Research Advantage, Inc.
  - Birmingham, Alabama, Forenede Stater, 35242
    - Cahaba Research Inc.
  - Haleyville, Alabama, Forenede Stater, 35565
    - Winston Technology Inc.
  - Hoover, Alabama, Forenede Stater, 35216
    - Clinical Research Consultants, Inc
  - Huntsville, Alabama, Forenede Stater, 35801
    - Rheumatology Associates of North Alabama, PC
  - Huntsville, Alabama, Forenede Stater, 35801
    - Medical Affiliated Research Center, Incorporated
  - Montgomery, Alabama, Forenede Stater, 36111
    - Montgomery Rheumatology Associates
  - Pelham, Alabama, Forenede Stater, 35124
    - James P. Beretta, PC
  - Pell City, Alabama, Forenede Stater, 35128
    - Alabama Clinical Research Associates
  - Pell City, Alabama, Forenede Stater, 35215
    - Pell City Internal and Family Medicine
  - Scottsboro, Alabama, Forenede Stater, 35768
    - Scottsboro Quick Care Clinic
  - Tuscaloosa, Alabama, Forenede Stater, 35406
    - Clinic for Rheumatic Diseases
  - Tuscumbia, Alabama, Forenede Stater, 35674
    - Terence T. Hart , MD
- Arizona
  - Chandler, Arizona, Forenede Stater, 85224
    - Clinical Research Advantage Inc./ Warner Family Practice, PC
  - Gilbert, Arizona, Forenede Stater, 85234
    - ArthroCare, Arthritis Care & Research P.C.
  - Glendale, Arizona, Forenede Stater, 85306
    - Arizona Center For Clinical Research
  - Glendale, Arizona, Forenede Stater, 85306-4652
    - Clinical Research Advantage Inc., /Thunderbird Internal Medicine
  - Glendale, Arizona, Forenede Stater, 85308
    - Clinical Research Advantage, Inc./ Lenzmeier Family Medicine
  - Mesa, Arizona, Forenede Stater, 85206
    - Novara Clinical Research
  - Mesa, Arizona, Forenede Stater, 85213
    - Clinical Research Advantage, Inc.
  - Mesa, Arizona, Forenede Stater, 85206
    - Clinical Research Advantage, Inc./Central Arizona Medical Associates, PC
  - Peoria, Arizona, Forenede Stater, 85381
    - Sun Valley Arthritis Center, Limited
  - Phoenix, Arizona, Forenede Stater, 85023
    - Arizona Research Center, Inc.
  - Phoenix, Arizona, Forenede Stater, 85051
    - 43rd Medical Associates, P.C.
  - Phoenix, Arizona, Forenede Stater, 85016
    - Lovelace Scientific Resources, Inc.
  - Phoenix, Arizona, Forenede Stater, 85018
    - Clinical Research Advantage, Inc./ Family Practice Specialists, LTD
  - Phoenix, Arizona, Forenede Stater, 85020
    - NPHC Research
  - Phoenix, Arizona, Forenede Stater, 85021
    - Phoenix Clinical
  - Phoenix, Arizona, Forenede Stater, 85032
    - Precision Trials AZ. LLC; AZ
  - Scottsdale, Arizona, Forenede Stater, 85258
    - Advanced Arthritis Care and Research
  - Scottsdale, Arizona, Forenede Stater, 85254
    - Southwest Health Ltd.
  - Scottsdale, Arizona, Forenede Stater, 85258
    - Arizona Pain Specialist, PLLC
  - Scottsdale, Arizona, Forenede Stater, 85258
    - Sonora Quest Laboratories
  - Sierra Vista, Arizona, Forenede Stater, 85635
    - Cochise Clinical Research
  - Tempe, Arizona, Forenede Stater, 85283
    - Clinical Research Advantage, Inc./Fiel Family and Sports Medicine, PC
  - Tempe, Arizona, Forenede Stater, 85282
    - Clinical Research Advantage, Inc./Skyline Medical Center PC
  - Tempe, Arizona, Forenede Stater, 85282
    - Clinical Research Advantage, Inc./Urban Family Practice Associates, PC
  - Tempe, Arizona, Forenede Stater, 85282
    - Clinical Research Advantage, Inc./Warner Family Practice, PC
  - Tempe, Arizona, Forenede Stater, 85282
    - Clinical Research Advantage, Inc/Manning Family Care
  - Tempe, Arizona, Forenede Stater, 85282
    - Clinical Research Advantage, Incl Colorado Springs Health Partners, East
  - Tempe, Arizona, Forenede Stater, 85282
    - Family Medicine Associates/Clinical Research Advantage
  - Tucson, Arizona, Forenede Stater, 85741
    - Genova Clinical Research
  - Tucson, Arizona, Forenede Stater, 85745
    - Eclipse Clinical Research
  - Tucson, Arizona, Forenede Stater, 85712
    - ARA-Arizona Research Associates
  - Tucson, Arizona, Forenede Stater, 85712
    - Canyon Clinical Research LLC
  - Tucson, Arizona, Forenede Stater, 85712
    - Tucson Clinical Researh
  - Tucson, Arizona, Forenede Stater, 85715
    - ACRC/Arizona Clinical Research Center, Incorporated
  - Tucson, Arizona, Forenede Stater, 85741
    - Clinical Research Advantage, Inc./ Orange Grove Family Practice
- Arkansas
  - Fayetteville, Arkansas, Forenede Stater, 72703
    - Fayetteville Diagnostic Clinic Limited
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Lynn Institute of the Ozarks
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Hearne Family Practice Clinic
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Larry S. Watkins, M.D.
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Rx Medical Research of AR
- California
  - Anaheim, California, Forenede Stater, 92805
    - Advanced Research Center
  - Anaheim, California, Forenede Stater, 92804
    - Anaheim Family Medical Center
  - Artesia, California, Forenede Stater, 90701
    - Advanced Arthritis & Rheumatology Center
  - Azusa, California, Forenede Stater, 91702
    - Bina Akamdar MD
  - Bell, California, Forenede Stater, 90201
    - Rx for Life, Inc
  - Carlsbad, California, Forenede Stater, 92008
    - Clinical Research Advantage Inc., /Cassidy Medical Group-Carlsbad
  - Carmichael, California, Forenede Stater, 95608
    - Northern California Research
  - Carmichael, California, Forenede Stater, 95608
    - Capitol Interventional Cardiology
  - Encinitas, California, Forenede Stater, 92024
    - CORE Orthopaedic Medical Center
  - Escondido, California, Forenede Stater, 92025
    - Arthritis Medical Clinic of North County, Inc.
  - Fair Oaks, California, Forenede Stater, 95628
    - Med Investigations, Inc.
  - Fresno, California, Forenede Stater, 93720
    - Valley Research
  - Greenbrae, California, Forenede Stater, 94904
    - Creekside Clinical Research
  - Hemet, California, Forenede Stater, 92543
    - C. V. Mehta, MD Medical Corporation
  - Huntington Beach, California, Forenede Stater, 92646
    - Talbert Medical Group
  - Huntington Park, California, Forenede Stater, 90255
    - Alia Clinical Research, INC
  - Huntington Park, California, Forenede Stater, 90255
    - Time Clinical Research Inc.
  - Irvine, California, Forenede Stater, 92604
    - Lindora Research Center
  - Irvine, California, Forenede Stater, 92618
    - Office of Dr. Robert L. Freed, MD
  - Laguna Hills, California, Forenede Stater, 92653
    - Prime Care Clinical Research
  - Laguna Hills, California, Forenede Stater, 92653
    - Office of Dr. Alan Schenk
  - Lakewood, California, Forenede Stater, 90712
    - Jeremy Anuntiyo
  - Lakewood, California, Forenede Stater, 90712
    - Premiere Clinical Research, LLC
  - Lakewood, California, Forenede Stater, 90712
    - Stuart J. Finkelstein
  - Lincoln, California, Forenede Stater, 95648
    - Clinical Trials Research
  - Loma Linda, California, Forenede Stater, 92357
    - VA Loma Linda Healthcare System
  - Lomita, California, Forenede Stater, 90717
    - Narbonne Multi-Specialty Medical Group Inc.
  - Long Beach, California, Forenede Stater, 90806
    - Office of Dr. Arvind J. Mehta
  - Long Beach, California, Forenede Stater, 90806
    - Pacific Internal Medicine Group, Inc
  - Long Beach, California, Forenede Stater, 90807-0000
    - Long Beach Center For Clinical Research
  - Long Beach, California, Forenede Stater, 90807
    - National Institute of Clinical Research
  - Long Beach, California, Forenede Stater, 90813
    - Alliance Research, LLC
  - Los Alamitos, California, Forenede Stater, 90720
    - Valerius Medical Group and Research Center
  - Los Angeles, California, Forenede Stater, 90045
    - Pacific Arthritis Care Center
  - Los Angeles, California, Forenede Stater, 90029
    - IMD Medical Group
  - Los Angeles, California, Forenede Stater, 90057
    - Wagdy W. Kades, MD, Inc.
  - Los Gatos, California, Forenede Stater, 95032
    - Samaritan Center for Medical Research Medical Group
  - Los Osos, California, Forenede Stater, 93402
    - Office of Lewis Gamarra, MD M.P.H.
  - Lynwood, California, Forenede Stater, 90262
    - Adegbenga A. Adetola, M.D.
  - Mission Hills, California, Forenede Stater, 91345
    - Facey Medical Group
  - North Hollywood, California, Forenede Stater, 91606
    - Providence Clinical Research
  - Palm Springs, California, Forenede Stater, 92262
    - Desert Medical Group
  - Palos Verdes Estates, California, Forenede Stater, 90274
    - The Office of Dr. Marcos Yang
  - Paramount, California, Forenede Stater, 90723
    - Bayview Research Group, LLC
  - Roseville, California, Forenede Stater, 95661
    - Sierra Rheumatology
  - Sacramento, California, Forenede Stater, 95823
    - Center for Clinical Trials of Sacramento, Inc.
  - Sacramento, California, Forenede Stater, 95825
    - Sacramento Heart and Vascular Research Center
  - San Diego, California, Forenede Stater, 92108
    - San Diego Arthritis Medical Clinic
  - San Diego, California, Forenede Stater, 92123
    - Medical Associates Research Group
  - San Diego, California, Forenede Stater, 92103-6204
    - California Research Foundation
  - San Diego, California, Forenede Stater, 92120
    - Wetlin Research Associates, Inc
  - San Jose, California, Forenede Stater, 95116
    - San Jose Valley Research, Inc.
  - San Leandro, California, Forenede Stater, 94578
    - Comprehensive Adult Risk Evaluation
  - San Leandro, California, Forenede Stater, 94578
    - East Bay Rheumatology Medical Group Inc
  - San Luis Obispo, California, Forenede Stater, 93405
    - Coastal Medical Research Group, Inc.
  - San Luis Obispo, California, Forenede Stater, 93401
    - Central Coast Pathology Consultants
  - San Luis Obispo, California, Forenede Stater, 93405
    - Family Medical Center
  - Santa Ana, California, Forenede Stater, 92704
    - Office of Ajay G. Meka, MD
  - Santa Maria, California, Forenede Stater, 93454
    - Pacific Arthritis Center Medical Group
  - Santa Monica, California, Forenede Stater, 90404
    - Orrin M. Troum & Medical Associates
  - Santa Rosa, California, Forenede Stater, 95403
    - Northern California Medical Associates
  - Sherman Oaks, California, Forenede Stater, 91423
    - Robert Simon, MD
  - Stockton, California, Forenede Stater, 95204
    - St. Joseph Medical Associates
  - Thousand Oaks, California, Forenede Stater, 91360
    - Westlake Medical Research
  - Torrance, California, Forenede Stater, 90503
    - Paradigm Clinical Research Institute, Inc.
  - Tustin, California, Forenede Stater, 92780
    - Orange County Research Center
  - Upland, California, Forenede Stater, 91786
    - Inland Rheumatology Clinical Trials, Inc.
  - Upland, California, Forenede Stater, 91786
    - Inland Rheumatology and Osteoporosis Medical Group
  - Valley Village, California, Forenede Stater, 91607
    - Bayview Research Group
  - Van Nuys, California, Forenede Stater, 91405
    - Medvin Clinical Research
  - West Covina, California, Forenede Stater, 91790
    - Center for Clinical Trials of San Gabriel
  - Whittier, California, Forenede Stater, 90606
    - Agilence Arthritis and Osteoporosis Medical Center, Inc.
  - Wilmington, California, Forenede Stater, 90744
    - Avalon Family Medical Group
- Colorado
  - Arvada, Colorado, Forenede Stater, 80005
    - Darrell E. Gorman, MD
  - Aurora, Colorado, Forenede Stater, 80012
    - Aurora Denver Cardiology Associates
  - Colorado Springs, Colorado, Forenede Stater, 80920
    - Lynn Institute of the Rockies
  - Colorado Springs, Colorado, Forenede Stater, 80918
    - Azmi Emil Farag, MD
  - Colorado Springs, Colorado, Forenede Stater, 80922
    - Colorado Springs Health Partners- East/Clinical Research Advantage
  - Denver, Colorado, Forenede Stater, 80209
    - Mountain View Clinical Research, Inc.
  - Fort Collins, Colorado, Forenede Stater, 80525
    - Saint Luke's Medical Clinic
  - Golden, Colorado, Forenede Stater, 80401
    - New West Physicians
  - Highlands Ranch, Colorado, Forenede Stater, 80130
    - Ranch View Family Medicine
  - Lakewood, Colorado, Forenede Stater, 80227
    - Colorado Center for Bone Research PC
  - Littleton, Colorado, Forenede Stater, 80120
    - South Denver Cardiology Associates, PC
  - Pueblo, Colorado, Forenede Stater, 81008
    - Lynn Institute of Pueblo
- Connecticut
  - Bridgeport, Connecticut, Forenede Stater, 06606
    - Connecticut Clinical Research, Llc
  - Bristol, Connecticut, Forenede Stater, 06010
    - Connecticut Gastroenterology Institute
  - Hamden, Connecticut, Forenede Stater, 06518
    - Arthritis and Osteoporosis Center, PC
  - Hamden, Connecticut, Forenede Stater, 06518
    - Robert Lang, MD, P.C.
  - New London, Connecticut, Forenede Stater, 06320
    - Coastal Connecticut Research, LLC
  - New London, Connecticut, Forenede Stater, 06320
    - Office of Edward J. McDermott, Jr., MD
  - Stamford, Connecticut, Forenede Stater, 06905
    - Stamford Therapeutics Consortium
  - Stamford, Connecticut, Forenede Stater, 06905
    - Orthopaedics Foundation for Active Lifestyles
  - Trumbull, Connecticut, Forenede Stater, 06611
    - New England Research Associates, LLC
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Arthritis Center of Connecticut
- Delaware
  - Lewes, Delaware, Forenede Stater, 19958
    - Rheumatology Consultants of Delaware
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20003
    - Office of Cynthia Morgan, MD
  - Washington, District of Columbia, Forenede Stater, 20006
    - The Center For Rheumatology And Bone Research
- Florida
  - Atlantis, Florida, Forenede Stater, 33462
    - Medical Specialist of the Palm Beaches
  - Aventura, Florida, Forenede Stater, 33180
    - South Florida Medical Research
  - Boca Raton, Florida, Forenede Stater, 33486
    - RASF - Clinical Research Center
  - Boynton Beach, Florida, Forenede Stater, 33472
    - Orthopedic Research Institute
  - Brandon, Florida, Forenede Stater, 33511
    - Clinical Research Of Brandon, LLC
  - Chipley, Florida, Forenede Stater, 32428
    - Family Healthcare of Chipley
  - Chipley, Florida, Forenede Stater, 32428
    - Health First Clinical Research Group, Inc.
  - Chipley, Florida, Forenede Stater, 32428
    - Southern Family Healthcare and Health First Research Group Inc.
  - Clearwater, Florida, Forenede Stater, 33756
    - Innovative Research of West Florida, Inc.
  - Clearwater, Florida, Forenede Stater, 33765
    - Clinical Research of West Florida
  - Clearwater, Florida, Forenede Stater, 33755
    - Florida Research & Testing, LLC
  - Clearwater, Florida, Forenede Stater, 33756
    - Alba Clinical Research
  - Clearwater, Florida, Forenede Stater, 33756
    - Appletree Medical
  - Cocoa, Florida, Forenede Stater, 32927
    - Rameshwar N. Mathur, MD, PA
  - Crystal River, Florida, Forenede Stater, 34429
    - Nature Coast Clinical Research, LLC
  - Daytona Beach, Florida, Forenede Stater, 32114
    - Atlantic Institute of Clinical Research
  - Daytona Beach, Florida, Forenede Stater, 32117
    - International Medical Research
  - DeBary, Florida, Forenede Stater, 32713
    - Omega Research Consultants, LLC
  - DeBary, Florida, Forenede Stater, 32713
    - Physicians Research Alliance, LLC
  - DeFuniak Springs, Florida, Forenede Stater, 32435
    - Doctors Medical center of Walton County
  - DeLand, Florida, Forenede Stater, 32720
    - Avail Clinical Research, LLC
  - DeLand, Florida, Forenede Stater, 32720
    - Florida Research Associates, LLC/Florida Orthopaedic Associates, P.A.
  - Deerfield Beach, Florida, Forenede Stater, 33442
    - Deerfield Beach Cardiology Associates
  - Delray Beach, Florida, Forenede Stater, 33446
    - Cohen Medical Associates, PA
  - Destin, Florida, Forenede Stater, 32540
    - Clark Family Medicine & Emerald Coast Research Group
  - Destin, Florida, Forenede Stater, 32541
    - SJS Clinical Research, Inc
  - Dunedin, Florida, Forenede Stater, 34698
    - Robert W. Levin MD
  - Edgewater, Florida, Forenede Stater, 32132
    - Riverside Clinical Research
  - Fleming Island, Florida, Forenede Stater, 32003
    - Fleming Island Center For Clinical Research
  - Fort Lauderdale, Florida, Forenede Stater, 33308
    - Invesclinic
  - Fort Lauderdale, Florida, Forenede Stater, 33316
    - M&O Clinical Research, LLC
  - Fort Lauderdale, Florida, Forenede Stater, 33316
    - Maxine Hamilton, MD PA
  - Fort Lauderdale, Florida, Forenede Stater, 33334
    - Holy Cross Medical Group Northridge Internal Medicine
  - Fort Myers, Florida, Forenede Stater, 33912
    - Clinical Physiology Associates
  - Fort Walton Beach, Florida, Forenede Stater, 32547
    - Emerald Coast Mood & Memory
  - Fort Walton Beach, Florida, Forenede Stater, 32547
    - White-Wilson Medical Center, PA
  - Gainesville, Florida, Forenede Stater, 32610
    - University of Florida
  - Gainesville, Florida, Forenede Stater, 32610
    - Shands at the University of Florida
  - Gainesville, Florida, Forenede Stater, 32605
    - Florida Research Network, LLC
  - Gainesville, Florida, Forenede Stater, 32607
    - Southeastern Integrated Medical, PL
  - Gainesville, Florida, Forenede Stater, 32605
    - Cardiology West
  - Hialeah, Florida, Forenede Stater, 33012
    - Indago Research & Health Center, Inc.
  - Hialeah, Florida, Forenede Stater, 33012
    - Reliable Clinical Research, LLC
  - Hialeah, Florida, Forenede Stater, 33010
    - Genetic Medical Research Corporation
  - Hialeah, Florida, Forenede Stater, 33012
    - Direct Helpers Medical Center, Inc.
  - Hollywood, Florida, Forenede Stater, 33021
    - Orthopaedic Associates of South Broward, P.A.
  - Homestead, Florida, Forenede Stater, 33030
    - Advanced Research Institute of Miami
  - Hudson, Florida, Forenede Stater, 34667
    - Pasco Cardiology Center
  - Inverness, Florida, Forenede Stater, 34452
    - Nature Coast Clinical Research
  - Jacksonville, Florida, Forenede Stater, 32205
    - Westside Center for Clinical Research
  - Jacksonville, Florida, Forenede Stater, 32216
    - East Coast Institute for Research, LLC
  - Jacksonville, Florida, Forenede Stater, 32216
    - Jacksonville Center for Clincal Research
  - Jacksonville, Florida, Forenede Stater, 32216
    - St. Vincent's Cardiology
  - Jupiter, Florida, Forenede Stater, 33458
    - Drug Study Institute
  - Jupiter, Florida, Forenede Stater, 33458
    - Dr. Ricardo A. Bedoya, M.D.
  - Kissimmee, Florida, Forenede Stater, 34744
    - Christopher Chappel
  - Lake Mary, Florida, Forenede Stater, 32746
    - Florida Arthritis Center, LLC
  - Lehigh Acres, Florida, Forenede Stater, 33936
    - Pedro Ylisastigui, MD
  - Longwood, Florida, Forenede Stater, 32779
    - Adult Medicine Specialists
  - Longwood, Florida, Forenede Stater, 32779
    - Genesis Research International
  - Madeira Beach, Florida, Forenede Stater, 33708
    - Doctors Inn
  - Marianna, Florida, Forenede Stater, 32446
    - Everest Medical Care and Palm Court Research Group
  - Marianna, Florida, Forenede Stater, 32446
    - Panhandle Family Care Associates & Emerald Coast Research Group
  - Marianna, Florida, Forenede Stater, 32446
    - The Doctor's Office
  - Melbourne, Florida, Forenede Stater, 32901
    - Holmes Regional Medical Center
  - Melbourne, Florida, Forenede Stater, 32901
    - Health First Medical Group
  - Merritt Island, Florida, Forenede Stater, 32953
    - Pharmaceutical Research Associates
  - Miami, Florida, Forenede Stater, 33126
    - Pharmax Research Clinic
  - Miami, Florida, Forenede Stater, 33175
    - New Horizon Research Center
  - Miami, Florida, Forenede Stater, 33176
    - Miami Cardiology Group
  - Miami, Florida, Forenede Stater, 33165
    - Future Care Solution, LLC
  - Miami, Florida, Forenede Stater, 33137
    - Miami International Cardiology Consultants
  - Miami, Florida, Forenede Stater, 33143
    - Well Pharma Medical Research Corporation
  - Miami, Florida, Forenede Stater, 33142
    - Florida Medical Center & Research, Inc.
  - Miami, Florida, Forenede Stater, 33032
    - Homestead Associates in Research, Inc
  - Miami, Florida, Forenede Stater, 33134
    - Life Spring Research Foundation
  - Miami, Florida, Forenede Stater, 33143
    - The Center for Arthritis and Rheumatic Diseases
  - Miami, Florida, Forenede Stater, 33144
    - DC Health Clinical Trials
  - Miami, Florida, Forenede Stater, 33144
    - School of Clinical Research USA, LLC
  - Miami, Florida, Forenede Stater, 33165
    - Advance Medical Research Services, Corp
  - Miami, Florida, Forenede Stater, 33185
    - M & M Medical Center
  - Miami, Florida, Forenede Stater, 33186
    - Office of Dr. Juvenal E. Martinez, MD, PA
  - Miami Beach, Florida, Forenede Stater, 33181
    - Orthopaedic Specialist of Miami Beach
  - Miami Gardens, Florida, Forenede Stater, 33169
    - AMPM Research Clinic
  - Miami Lakes, Florida, Forenede Stater, 33014
    - Crystal Biomedical Research, LLC
  - Miami Lakes, Florida, Forenede Stater, 33014
    - Pembroke Clinical Trials
  - Naples, Florida, Forenede Stater, 34102
    - Anchor Research Center
  - Naples, Florida, Forenede Stater, 34102
    - Jeffrey Alper M.D. Research
  - Naples, Florida, Forenede Stater, 34108
    - Anchor Health Centers
  - Naples, Florida, Forenede Stater, 34119
    - Medical Surgical Specialists, Physicians Regional Medical Center
  - New Port Richey, Florida, Forenede Stater, 34652
    - Suncoast Clinical Research, Inc.
  - Ocala, Florida, Forenede Stater, 34474
    - Ocala Rheumatology Research Center
  - Ocala, Florida, Forenede Stater, 34474
    - Paddock Park Clinical Research
  - Ocala, Florida, Forenede Stater, 34471-5117
    - Magnolia Research Group, Inc.
  - Ocala, Florida, Forenede Stater, 34474
    - Southeastern Rehabilitation Medicine
  - Ocala, Florida, Forenede Stater, 34474
    - Tequesta Research Group
  - Ocoee, Florida, Forenede Stater, 34761
    - CEC Research, INC.
  - Orlando, Florida, Forenede Stater, 32806
    - Compass Research, LLC
  - Orlando, Florida, Forenede Stater, 32803
    - Florida Hospital
  - Orlando, Florida, Forenede Stater, 32803-1849
    - Florida Heart Group, PA
  - Orlando, Florida, Forenede Stater, 32806
    - DCT FMC, LLC dba Discovery Clinical Trials
  - Orlando, Florida, Forenede Stater, 32806
    - DCT-FMC, LLC dba Discovery Clinical Trials
  - Orlando, Florida, Forenede Stater, 32814
    - Arthur L. Hall MD PA
  - Oviedo, Florida, Forenede Stater, 32765
    - Block and Nation, PA
  - Palm Harbor, Florida, Forenede Stater, 34684
    - Arthritis Research Of Florida, Inc.
  - Palm Harbor, Florida, Forenede Stater, 34684
    - Florida Med Center of Countryside
  - Pembroke Pines, Florida, Forenede Stater, 33027
    - South Broward Research LLC
  - Pembroke Pines, Florida, Forenede Stater, 33024
    - Rene CaSanova Medical Office Inc
  - Pembroke Pines, Florida, Forenede Stater, 33026
    - Boulevard Professional Centre
  - Pembroke Pines, Florida, Forenede Stater, 33026
    - Research Physician Network Alliance
  - Pembroke Pines, Florida, Forenede Stater, 33029
    - South Florida Research Solutions, LLC
  - Pinellas Park, Florida, Forenede Stater, 33782
    - DMI Research, Inc.
  - Plantation, Florida, Forenede Stater, 33322
    - Sunbelt Research, LLC
  - Plantation, Florida, Forenede Stater, 33323
    - Boca Raton Clinical Research
  - Ponte Vedra, Florida, Forenede Stater, 32081
    - St. Johns Center for Clinical Research
  - Port Orange, Florida, Forenede Stater, 32129
    - Accord Clinical Research, LLC
  - Port Richey, Florida, Forenede Stater, 34668
    - Administrative Address: Florida Arthritis & Osteoporosis Center
  - Sarasota, Florida, Forenede Stater, 34239
    - Heart & Vascular Center Research
  - Sebastian, Florida, Forenede Stater, 32958
    - Edgar R. Blecker, MD
  - Tamarac, Florida, Forenede Stater, 33321
    - Phoenix Clinical Research, LLC.
  - Tampa, Florida, Forenede Stater, 33603
    - Clinical Research of West Florida
  - Tampa, Florida, Forenede Stater, 33613
    - Stedman Clinical Trials, LLC
  - Tampa, Florida, Forenede Stater, 33609-3018
    - Soutwest Florida Clinical Research Center
  - Tampa, Florida, Forenede Stater, 33609
    - Clinyx/Floria Cardiovascular
  - Tampa, Florida, Forenede Stater, 33613
    - West Wind'r Research
  - Tampa, Florida, Forenede Stater, 33614
    - Health Point Medical Group, Inc
  - Tampa, Florida, Forenede Stater, 33619-6364
    - Causeway Medical Clinic
  - Vero Beach, Florida, Forenede Stater, 32960
    - Office of Alastair C. Kennedy, MD
  - West Palm Beach, Florida, Forenede Stater, 33409
    - Palm Beach Research Center
  - West Palm Beach, Florida, Forenede Stater, 33401
    - Metabolic Research Institute, Incorporated
  - Winter Park, Florida, Forenede Stater, 32792
    - Central Florida Primary Care
  - Zephyrhills, Florida, Forenede Stater, 33542
    - Florida Medical Clinic, PA
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30342
    - Arthritis and Rheumatology of Georgia
  - Atlanta, Georgia, Forenede Stater, 30309
    - Piedmont Heart Institute
  - Atlanta, Georgia, Forenede Stater, 30342
    - Atlanta Vascular Research Foundation
  - Atlanta, Georgia, Forenede Stater, 30308
    - The Kaufmann Clinic
  - Atlanta, Georgia, Forenede Stater, 30342
    - Atlanta Center for Clinical Research, Corp.
  - Atlanta, Georgia, Forenede Stater, 30342
    - Executive Health and Research Associates
  - Augusta, Georgia, Forenede Stater, 30909
    - Masters of Clinical Research, Inc.
  - Augusta, Georgia, Forenede Stater, 30904
    - Southern Clinical Research and Management, Inc. (SCRAM)
  - Bainbridge, Georgia, Forenede Stater, 39819
    - Amelia Medical Plaza
  - Bainbridge, Georgia, Forenede Stater, 39819
    - Bainbridge Medical Associates
  - Cairo, Georgia, Forenede Stater, 39828
    - Abdul Bari MD Inc
  - Cairo, Georgia, Forenede Stater, 39828
    - Southern Clinical Research Management and Consulting
  - Duluth, Georgia, Forenede Stater, 30096
    - North Georgia Rheumatology Group, PC
  - Gainesville, Georgia, Forenede Stater, 30501
    - United Osteoporosis Centers
  - Lawrenceville, Georgia, Forenede Stater, 30046
    - North Georgia Rheumatology Group, PC
  - Lilburn, Georgia, Forenede Stater, 30047
    - GCH Research Dr. G Craig Heigerick DO
  - Macon, Georgia, Forenede Stater, 31201
    - Mercer University Mercer Medicine
  - Marietta, Georgia, Forenede Stater, 30060
    - Drug Studies America
  - Marietta, Georgia, Forenede Stater, 30066
    - Drug Studies America
  - Marietta, Georgia, Forenede Stater, 30067
    - Clinical Research Advantage, Inc./Urban Family Practice Associates, PC
  - Norcross, Georgia, Forenede Stater, 30071
    - In-Quest Medical Research, LLC
  - Rome, Georgia, Forenede Stater, 30165-1698
    - Harbin Clinic
  - Roswell, Georgia, Forenede Stater, 30075
    - Atlanta Center for Clinical Research
  - Suwanee, Georgia, Forenede Stater, 30024
    - Herman Clinical Research, LLC
  - Thomasville, Georgia, Forenede Stater, 31792
    - Archibold Primary Care
  - Tucker, Georgia, Forenede Stater, 30084
    - Clinical Trial Providers, Inc.
  - Valdosta, Georgia, Forenede Stater, 31602
    - VSC
  - Woodstock, Georgia, Forenede Stater, 30189
    - North Georgia Clinical Research
  - Woodstock, Georgia, Forenede Stater, 30189
    - North Georgia Internal Medicine
  - Woodstock, Georgia, Forenede Stater, 30188
    - Kaufmann Clinic, INC
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96814
    - East-West Medical Research Institute
- Idaho
  - Boise, Idaho, Forenede Stater, 83702
    - Orthopedic Health Care Clinic
  - Boise, Idaho, Forenede Stater, 83702
    - Sonora Clinical Research, LLC
  - Boise, Idaho, Forenede Stater, 83713-0997
    - Eagle's View Family Medicine
  - Coeur d'Alene, Idaho, Forenede Stater, 83814
    - Coeur D'Alene Arthritis Clinic
  - Eagle, Idaho, Forenede Stater, 83616
    - CTL Research
  - Idaho Falls, Idaho, Forenede Stater, 83404
    - Women's Healthcare Associates P.A. dba Rosemark WomenCare Specialists
  - Meridian, Idaho, Forenede Stater, 83642
    - Advanced Clinical Research
  - Meridian, Idaho, Forenede Stater, 83642-6356
    - Idaho Arthritis and Osteoporosis Center
- Illinois
  - Aurora, Illinois, Forenede Stater, 60506
    - AMR Sakeena Research
  - Bloomingdale, Illinois, Forenede Stater, 60108
    - Arthur I Davida, MD PC
  - Chicago, Illinois, Forenede Stater, 60617
    - Claude Mandel Medical Center
  - Chicago, Illinois, Forenede Stater, 60611
    - Cardiac Wellness Consultants
  - Chicago, Illinois, Forenede Stater, 60611
    - Chicago Peripheral Nerve Center
  - Chicago, Illinois, Forenede Stater, 60611
    - ICCT Research International Incorporated
  - Evanston, Illinois, Forenede Stater, 60202
    - Windy City Orthopedics and Sports Medicine
  - Hazel Crest, Illinois, Forenede Stater, 60429
    - South Suburban Health Professional Group
  - Joliet, Illinois, Forenede Stater, 60435
    - Prairie Rheumatology Associates, SC
  - Lake Zurich, Illinois, Forenede Stater, 60047
    - Lake Zurich Family Treatment Center
  - O'Fallon, Illinois, Forenede Stater, 62269
    - Southern Illiniois Clinical Research Centre
  - Olympia Fields, Illinois, Forenede Stater, 60461
    - Speciality phhysicians of Illinois, LLC
  - Peoria, Illinois, Forenede Stater, 61614
    - Redhead Research Inc., dba Research Associates of Central Illinois
  - Rock Island, Illinois, Forenede Stater, 61201
    - Trinity Medical Center
  - Rockford, Illinois, Forenede Stater, 61103
    - Rockford Health Physicians
  - Springfield, Illinois, Forenede Stater, 62702
    - Springfield Clinic
  - Springfield, Illinois, Forenede Stater, 62703
    - Springfield Clinic
  - Springfield, Illinois, Forenede Stater, 62701
    - Prairie Cardiovascular Consultants
  - Springfield, Illinois, Forenede Stater, 62701
    - Prairie Education & Research
  - Vernon Hills, Illinois, Forenede Stater, 60061
    - Deerbrook Medical Associates
- Indiana
  - Anderson, Indiana, Forenede Stater, 46011
    - Community Clinical Research Center
  - Avon, Indiana, Forenede Stater, 46123
    - American Health Network of Indiana, LLC
  - Evansville, Indiana, Forenede Stater, 47714
    - Clinical Research Advantage, Inc.
  - Evansville, Indiana, Forenede Stater, 47714
    - Destiny Clinical Research, LLC
  - Evansville, Indiana, Forenede Stater, 47710
    - Robert D. Barnes, MD, LLC
  - Evansville, Indiana, Forenede Stater, 47725
    - Clinical Research Advantage/Family Medicine Associates
  - Franklin, Indiana, Forenede Stater, 46131
    - American Health Network of Indiana, LLC
  - Gary, Indiana, Forenede Stater, 46409
    - Internal Medicine Center of Northwest Indiana, P.C.
  - Granger, Indiana, Forenede Stater, 46530
    - Beacon Medical Group Rheumatology
  - Greenfield, Indiana, Forenede Stater, 46140-2834
    - American Health Network of IN, LLC
  - Indianapolis, Indiana, Forenede Stater, 46256
    - Dawes Fretzin Clinical Research Group, LLC
  - Indianapolis, Indiana, Forenede Stater, 46256
    - Dawes Fretzin Dermatology Group, LLC
  - Indianapolis, Indiana, Forenede Stater, 46227
    - Diagnostic Rheumatology And Research, PC
  - Indianapolis, Indiana, Forenede Stater, 46234
    - Investigators Research Group
  - Jeffersonville, Indiana, Forenede Stater, 47130
    - Arthritis Associates of Southern Indiana
  - Jeffersonville, Indiana, Forenede Stater, 47130
    - Research Institute of Middle America/River Cities Cardiology
  - LaPorte, Indiana, Forenede Stater, 46350
    - Beacon Medical Group LaPorte
  - Merrillville, Indiana, Forenede Stater, 46410
    - Cardiovascular Clinics, PC
  - Muncie, Indiana, Forenede Stater, 47304
    - Community Clinical Research Center
  - Munster, Indiana, Forenede Stater, 46321
    - Medical Specialists Clinical Research Center
  - Munster, Indiana, Forenede Stater, 46321
    - Medical Specialists
  - New Albany, Indiana, Forenede Stater, 47150
    - Arthritis Associates of Southern Indiana
  - Valparaiso, Indiana, Forenede Stater, 46383
    - Buynak Clinical Research
- Iowa
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Physician's Clinic of Iowa, PC
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Ridge Family Practice, PC/Clinical Research Advantage, Inc.
  - Davenport, Iowa, Forenede Stater, 52803
    - Midwest Cardiovascular Research Foundation
  - Des Moines, Iowa, Forenede Stater, 50316
    - Office of Jerrold V Flatt
  - Dubuque, Iowa, Forenede Stater, 52002
    - Medical Associates Clinic, PC
  - Waterloo, Iowa, Forenede Stater, 50701
    - Family Health Center of Waterloo, PC
  - Waterloo, Iowa, Forenede Stater, 50702
    - Northeast IA Medical Education Foundation/Family Practice Center
- Kansas
  - Arkansas City, Kansas, Forenede Stater, 67005
    - Heartland Research Associates LLC
  - Kansas City, Kansas, Forenede Stater, 66104
    - Community House of Wellness
  - Lansing, Kansas, Forenede Stater, 66043
    - Associates Reseach Inc.
  - Overland Park, Kansas, Forenede Stater, 66215
    - Pinnacle Medical Research
  - Overland Park, Kansas, Forenede Stater, 66210
    - Radiant Research, Inc.
  - Overland Park, Kansas, Forenede Stater, 66211
    - International Clinical Research Institute, Inc
  - Overland Park, Kansas, Forenede Stater, 66215
    - Arthritis Specialists of Greater KC
  - Overland Park, Kansas, Forenede Stater, 66215
    - Quivira Internal Medicine
  - Pratt, Kansas, Forenede Stater, 67124
    - Health Science Research Center
  - Wichita, Kansas, Forenede Stater, 67205
    - Heartland Research Associates, LLC
  - Wichita, Kansas, Forenede Stater, 67208
    - Via Christi Clinic
- Kentucky
  - Ashland, Kentucky, Forenede Stater, 41101
    - Howard L. Feinberg, D.O.
  - Bowling Green, Kentucky, Forenede Stater, 42101
    - Graves Gilbert Clinic
  - Bowling Green, Kentucky, Forenede Stater, 42101-1759
    - Graves Gilbert Clinic
  - Campbellsville, Kentucky, Forenede Stater, 42718
    - Internal Medicine Research Association
  - Elizabethtown, Kentucky, Forenede Stater, 42701
    - Center For Arthritis and Osteoporosis
  - Lexington, Kentucky, Forenede Stater, 40504
    - Arthritis Center of Lexington
  - Louisville, Kentucky, Forenede Stater, 40202
    - University Medical Associates
  - Louisville, Kentucky, Forenede Stater, 40213
    - Louisville Metabolic and Atherosclerosis Research Center
  - Louisville, Kentucky, Forenede Stater, 40202
    - Kentuckiana Center for Better Bone and Joint Health
  - Louisville, Kentucky, Forenede Stater, 40202
    - KY Research PLLC.
  - Richmond, Kentucky, Forenede Stater, 40475
    - Office of Gaurang B. Shah,MD, PSC
  - Richmond, Kentucky, Forenede Stater, 40475
    - Richmond Regional Research
- Louisiana
  - Bossier City, Louisiana, Forenede Stater, 71111
    - Chandler Family Practice
  - Shreveport, Louisiana, Forenede Stater, 71105
    - McFarland Family Clinic
  - Shreveport, Louisiana, Forenede Stater, 71115
    - TFD Research, LLC
- Maine
  - Auburn, Maine, Forenede Stater, 04210
    - Maine Research Associates
  - Biddeford, Maine, Forenede Stater, 04005
    - Southern Maine Health Care
  - Lewiston, Maine, Forenede Stater, 04240
    - Central Maine Heart & Vascular Institute
- Maryland
  - Baltimore, Maryland, Forenede Stater, 21209
    - Health Trends Research, LLC
  - Baltimore, Maryland, Forenede Stater, 21204
    - Chesapeake Cardiovascular Associates
  - Baltimore, Maryland, Forenede Stater, 21204
    - Midatlantic Cardiovascular Associates
  - Baltimore, Maryland, Forenede Stater, 21208
    - Midatlantic Cardiovascular Associates, Pa
  - Baltimore, Maryland, Forenede Stater, 21215
    - One Heart, LLC
  - Baltimore, Maryland, Forenede Stater, 21218
    - Chesapeake Cardiovascular Associates
  - Baltimore, Maryland, Forenede Stater, 21229
    - Midatlantic Cardiovascular Associates, Pa
  - Baltimore, Maryland, Forenede Stater, 21229
    - Saint Agnes HealthCare Incorporated
  - Baltimore, Maryland, Forenede Stater, 21234-4607
    - Stephen R Smith, MD FACP
  - Baltimore, Maryland, Forenede Stater, 21237
    - Midatlantic Cardiovascular Associates, Pa
  - Baltimore, Maryland, Forenede Stater, 21239
    - Peter A. Holt
  - Bel Air, Maryland, Forenede Stater, 21014
    - Midatlantic Cardiovascular Associates PA
  - Charlotte Hall, Maryland, Forenede Stater, 20622
    - Shah Associates MD, LLC
  - Columbia, Maryland, Forenede Stater, 21044
    - Johns Hopkins University
  - Columbia, Maryland, Forenede Stater, 21044-2914
    - Cardiovascular Specialists, LLC
  - Cumberland, Maryland, Forenede Stater, 21502
    - The Osteoporosis & Clinical Trials Center
  - Frederick, Maryland, Forenede Stater, 21702
    - Arthritis Treatment Center
  - Greenbelt, Maryland, Forenede Stater, 20770
    - The Spine & Joint Center
  - Hagerstown, Maryland, Forenede Stater, 21740
    - Klein & Associates, MD, PA
  - North East, Maryland, Forenede Stater, 21901
    - Community Health Research
  - Oxon Hill, Maryland, Forenede Stater, 20745
    - MD Medical Research
  - Prince Frederick, Maryland, Forenede Stater, 20678
    - Shah Associates
  - Rockville, Maryland, Forenede Stater, 20850
    - Cardiac Associates, Shady Grove Adventist Hospital
  - Rockville, Maryland, Forenede Stater, 20850
    - The Center For Rheumatology And Bone Research
  - Rockville, Maryland, Forenede Stater, 20854
    - Rockville Internal Medicine Group
  - Towson, Maryland, Forenede Stater, 21204
    - IRC Clinics
  - Westminster, Maryland, Forenede Stater, 21157-6160
    - Midatlantic Cardiovascular Associates, P.A.
  - Wheaton, Maryland, Forenede Stater, 20902
    - The Center For Rheumatology And Bone Research
- Massachusetts
  - Ayer, Massachusetts, Forenede Stater, 01432
    - Primary Care Cardiology Research
  - Fall River, Massachusetts, Forenede Stater, 02720
    - Phase III Clinical Research
  - Fall River, Massachusetts, Forenede Stater, 02720
    - Genesis Clinical Research & Consulting
  - Fall River, Massachusetts, Forenede Stater, 02720
    - NECCR Internal Medicine and Cardiology Associates, LLC
  - Haverhill, Massachusetts, Forenede Stater, 01830
    - Pentucket Medical Associates, Incorporated
  - Hyannis, Massachusetts, Forenede Stater, 02601
    - Clinical Research Center of Cape Cod, Inc.
  - Natick, Massachusetts, Forenede Stater, 01760
    - Charles River Medical Associates, Pchi
  - New Bedford, Massachusetts, Forenede Stater, 02740
    - Novex Clinical Research, LLC
  - Northampton, Massachusetts, Forenede Stater, 01062
    - Northampton Internal Medicine Associates, PC
  - Springfield, Massachusetts, Forenede Stater, 01105
    - FutureCare Studies
  - Worcester, Massachusetts, Forenede Stater, 01605
    - Reliant Medical Group, Inc.
- Michigan
  - Bay City, Michigan, Forenede Stater, 48706
    - Great Lakes Research Group, Incorporated
  - Benzonia, Michigan, Forenede Stater, 49616
    - Professional Clinical Research-Benzonia
  - Cadillac, Michigan, Forenede Stater, 49601
    - Cadillac Clinical Research
  - Detroit, Michigan, Forenede Stater, 48221
    - Livernois Family Medical Services
  - Eaton Rapids, Michigan, Forenede Stater, 48827
    - Office of Dr. Susan Courtnage
  - Flint, Michigan, Forenede Stater, 48532
    - McLaren Regional Medical Center-Research Dept.
  - Grand Rapids, Michigan, Forenede Stater, 49506
    - Grand Valley Medical Specialist, PLC
  - Grand Rapids, Michigan, Forenede Stater, 49506
    - Spectrum Health Medical Group-Rheumatology
  - Grand Rapids, Michigan, Forenede Stater, 49546
    - Michigan Medical Cardiovascular PC
  - Interlochen, Michigan, Forenede Stater, 49643
    - Professional Clinical Research
  - Lansing, Michigan, Forenede Stater, 48910-8595
    - Justus J Fiechtner, MD
  - Saginaw, Michigan, Forenede Stater, 48601
    - Michigan CardioVascular Institute
  - Saginaw, Michigan, Forenede Stater, 48602
    - Synergy Medical Education Alliance
  - Saint Clair Shores, Michigan, Forenede Stater, 48081
    - Shores Rheumatology
  - Troy, Michigan, Forenede Stater, 48085
    - Oakland Medical Research Center
  - Troy, Michigan, Forenede Stater, 48098
    - Troy Internal Medicine Research
- Minnesota
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Luke's Hospital Association of Duluth
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Luke's Hospital Association of Duluth, DBA St Luke's Rheumatology Assoc.
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Luke's Hospital Association of Duluth, Inc.
  - Saint Cloud, Minnesota, Forenede Stater, 56303-1901
    - Central Minnesota Heart Center at St. Cloud Hospital
  - Saint Paul, Minnesota, Forenede Stater, 55102
    - St. Paul Heart Clinic
- Mississippi
  - Biloxi, Mississippi, Forenede Stater, 39531
    - The Center for Clinical Trials
  - Port Gibson, Mississippi, Forenede Stater, 39150
    - Planters Clinic
  - Tupelo, Mississippi, Forenede Stater, 38801
    - North Mississippi Medical Clinics, Inc.
- Missouri
  - Cape Girardeau, Missouri, Forenede Stater, 63703
    - Cape Girardeau Physicians Associates
  - Florissant, Missouri, Forenede Stater, 63031
    - Patterson Medical Clinic / d.b.a. Prime Care Research Associates
  - Jefferson City, Missouri, Forenede Stater, 65109
    - Jefferson City Medical Group
  - Jefferson City, Missouri, Forenede Stater, 65101
    - Allergy Asthma Immunology Services, LLC
  - Kansas City, Missouri, Forenede Stater, 64108-2792
    - University of Missouri Kansas City School of Medicine
  - Kansas City, Missouri, Forenede Stater, 64108
    - Truman Medical Center, Inc.
  - Kansas City, Missouri, Forenede Stater, 64133
    - Clinical Research Advantage, Inc./Manning Family Care, LLC
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Sundance Clinical Research, LLC
  - Saint Louis, Missouri, Forenede Stater, 63128
    - St. Louis Center for Clinical Research
  - Saint Louis, Missouri, Forenede Stater, 63131
    - Physician Groups, LC, DBA Rheumatology and Internal Medicine Associates
  - Saint Louis, Missouri, Forenede Stater, 63139-2909
    - Southampton Healthcare, Inc.
  - Saint Louis, Missouri, Forenede Stater, 63139
    - Barbara A. Caciolo, MD
  - Saint Louis, Missouri, Forenede Stater, 63141
    - A & A Pain Institute
  - Springfield, Missouri, Forenede Stater, 65807
    - Mercy Medical Research Institute
  - Washington, Missouri, Forenede Stater, 63090
    - Patients First Health Care, LLC
- Montana
  - Kalispell, Montana, Forenede Stater, 59901
    - Glacier View Research Institute, Cardiology
- Nebraska
  - Alliance, Nebraska, Forenede Stater, 69301
    - Alliance Medical Center
  - Alliance, Nebraska, Forenede Stater, 69301
    - Cody Medical Associates
  - Bellevue, Nebraska, Forenede Stater, 68005
    - Bellevue Family Practice/Clinical Research Advantage, Inc.
  - Elkhorn, Nebraska, Forenede Stater, 68022
    - Clinical Research Advantage, Inc./ Skyline Medical Center, PC
  - Fremont, Nebraska, Forenede Stater, 68025
    - Clinical Research Advantage, Inc./Prairie Fields Family Medicine, PC
  - Grand Island, Nebraska, Forenede Stater, 68803
    - Internal Medicine Associates, PC
  - Lincoln, Nebraska, Forenede Stater, 68516
    - Lincoln Internal Medicine Associates
  - Lincoln, Nebraska, Forenede Stater, 68512
    - Physician, Research Collaboration, Southwest Family Health
  - North Platte, Nebraska, Forenede Stater, 69101
    - Platte River Nephrology
  - Omaha, Nebraska, Forenede Stater, 68114
    - Westroads Medical Group
  - Omaha, Nebraska, Forenede Stater, 68134
    - Heartland Clinical Research, Inc.
  - Omaha, Nebraska, Forenede Stater, 68114
    - Quality Clinical Research LLC
  - Omaha, Nebraska, Forenede Stater, 68144
    - Clinical Research Advantage, Inc./Primary Care Physicians, LLP
- Nevada
  - Henderson, Nevada, Forenede Stater, 89014
    - Clinical Research Advantage, Inc.
  - Henderson, Nevada, Forenede Stater, 89052
    - Clinical Research Advantage, Inc./Rita B. Chuang, MD, LLC
  - Incline Village, Nevada, Forenede Stater, 89451
    - Sierra Internal Medicine Associates
  - Las Vegas, Nevada, Forenede Stater, 89104
    - Clinical Research Center of Nevada
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Clinical Research Advantage/Peter Philander, MD
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Rancho Internal Medicine
  - Las Vegas, Nevada, Forenede Stater, 89130
    - Steven D. Folkerth, MD
  - Las Vegas, Nevada, Forenede Stater, 89146
    - Ladner Family Practice
  - North Las Vegas, Nevada, Forenede Stater, 89086
    - VA Southern Nevada Healthcare System
  - Reno, Nevada, Forenede Stater, 89502
    - Arthritis Center of Reno
- New Jersey
  - Clifton, New Jersey, Forenede Stater, 07012
    - New Jersey Physicians, LLC
  - Clifton, New Jersey, Forenede Stater, 07013
    - Clifton-Wallington Medical Group
  - Edison, New Jersey, Forenede Stater, 08817
    - Anderson and Collins, Clinical Research Inc.
  - Edison, New Jersey, Forenede Stater, 08817
    - Drs. Collins and Uthappa
  - Elizabeth, New Jersey, Forenede Stater, 07202
    - Central Jersey Health Care
  - Englewood, New Jersey, Forenede Stater, 07631-2507
    - Andron Medical Associates
  - Haddon Heights, New Jersey, Forenede Stater, 08035
    - Advocare Heights Primary Care
  - Hazlet, New Jersey, Forenede Stater, 07730
    - Hazlet Health Care
  - Lawrenceville, New Jersey, Forenede Stater, 08648
    - Family Care Physicians
  - Lawrenceville, New Jersey, Forenede Stater, 08648
    - Penn Cardiac Care at Mercer Bucks
  - Lindenwold, New Jersey, Forenede Stater, 08021
    - Family Medicine of Lindenwold
  - Medford, New Jersey, Forenede Stater, 08055
    - Rheumatology and Arthritis Associates PC
  - Midland Park, New Jersey, Forenede Stater, 07432-1969
    - Adult & Pediatric Rheumatology
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - The Valley Hospital
  - Sicklerville, New Jersey, Forenede Stater, 08081
    - Maynard Holgado LLC
  - Toms River, New Jersey, Forenede Stater, 08753
    - Shore Health Group
  - Trenton, New Jersey, Forenede Stater, 08618
    - Hopewell Valley Medical Group, P.A.
  - Voorhees, New Jersey, Forenede Stater, 08043
    - Arthritis, Rheumatic and Back Disease Associates, PA
  - Willingboro, New Jersey, Forenede Stater, 08046
    - Lourdes Medical Associates
- New York
  - Babylon, New York, Forenede Stater, 11702-2516
    - Kenneth F. Solinsky, MD
  - Brooklyn, New York, Forenede Stater, 11214
    - Lifeline Research Institute
  - Dunkirk, New York, Forenede Stater, 14048
    - Lee Medical Associates
  - Elmira, New York, Forenede Stater, 14905
    - AMS Research
  - Endwell, New York, Forenede Stater, 13760
    - Regional Clinical Research, Inc.
  - Hartsdale, New York, Forenede Stater, 10530
    - Drug Trials America, Inc.
  - Johnson City, New York, Forenede Stater, 13790
    - United Health Service Hospitals, Office of Clinical Trials
  - Kew Gardens, New York, Forenede Stater, 11415
    - IMA Medical Research PC
  - Lake Success, New York, Forenede Stater, 11042
    - NYU Langone Medical Center, Laura and Issac Perlmutter Cancer Center, Infusion Center
  - Lake Success, New York, Forenede Stater, 11042
    - NYU Langone Medical Center, Laura and Issac Perlmutter Cancer Center, Investigational Pharmacy
  - Lake Success, New York, Forenede Stater, 11042
    - NYU Langone Rheumatology Associates Long Island
  - Mamaroneck, New York, Forenede Stater, 10543
    - Office of Dr. Allen Chodock
  - Mineola, New York, Forenede Stater, 11501
    - Winthrop University Hospital / Clinical Trials Center
  - New York, New York, Forenede Stater, 10016-4974
    - New York University Pain Management Center
  - New York, New York, Forenede Stater, 10016
    - NYU Pain Research
  - New York, New York, Forenede Stater, 10021
    - Office of Dr. Richard Stern
  - North Massapequa, New York, Forenede Stater, 11758
    - DiGiovanna Family Care Center
  - Poughkeepsie, New York, Forenede Stater, 12601
    - Hudson Valley Heart Center
  - Rochester, New York, Forenede Stater, 14618
    - AAIR Research Center
  - Rosedale, New York, Forenede Stater, 11422
    - Institute for clinical studies
  - Smithtown, New York, Forenede Stater, 11787-2817
    - Rheumatology Associates of Long Island
  - Syosset, New York, Forenede Stater, 11791
    - Office of Dr. Chadia Morcos
  - Syracuse, New York, Forenede Stater, 13210-1775
    - Arthritis Health Associates
  - Syracuse, New York, Forenede Stater, 13210
    - Crouse Medical Practice, PLLC d/b/a Internist Associates of Central New York
  - Wantagh, New York, Forenede Stater, 11793
    - East Meadow Family Practice Associates, PC
  - West Seneca, New York, Forenede Stater, 14224
    - Southgate Medical Group
  - Westfield, New York, Forenede Stater, 14787
    - Great Lakes Medical Research
  - Williamsville, New York, Forenede Stater, 14221
    - Upstate Clinical Research Associates
  - Williamsville, New York, Forenede Stater, 14221
    - Buffalo Cardiology and Pulmonary Associates, PC
- North Carolina
  - Asheville, North Carolina, Forenede Stater, 28803
    - Asheville Arthritis & Osteoporosis, PA
  - Burlington, North Carolina, Forenede Stater, 27215
    - Kernodle Clinic Inc.
  - Calabash, North Carolina, Forenede Stater, 28467
    - Calabash Medical Center
  - Cary, North Carolina, Forenede Stater, 27518
    - PMG Research of Raleigh, LLC d/b/a PMG Research of Cary
  - Chapel Hill, North Carolina, Forenede Stater, 27514
    - Chapel Hill Family Medicine
  - Chapel Hill, North Carolina, Forenede Stater, 27599
    - Thurston Arthritis Reaserch Ctr
  - Charlotte, North Carolina, Forenede Stater, 28277
    - Sensenbrenner Primary Care
  - Charlotte, North Carolina, Forenede Stater, 28204
    - Mid Carolina Cardiology Research
  - Charlotte, North Carolina, Forenede Stater, 28204
    - Presbyterian Novant Heart and Wellness
  - Charlotte, North Carolina, Forenede Stater, 28207-1198
    - Arthritis and Osteoporosis Consultants of the Carolinas
  - Charlotte, North Carolina, Forenede Stater, 28209-3734
    - PMG Research of Charlotte
  - Charlotte, North Carolina, Forenede Stater, 28262
    - Barat Research Group, Inc.
  - Durham, North Carolina, Forenede Stater, 27705
    - Duke Health Center at Pickett Road
  - Greensboro, North Carolina, Forenede Stater, 27401
    - Bland Clinic, PA
  - Greensboro, North Carolina, Forenede Stater, 27408
    - Medication Management, LLC
  - Greenville, North Carolina, Forenede Stater, 27834
    - Physicians East, PA
  - Greenville, North Carolina, Forenede Stater, 27834
    - Physicians East P. A.
  - Hickory, North Carolina, Forenede Stater, 28602
    - PMG Research of Hickory, LLC
  - Hickory, North Carolina, Forenede Stater, 28601
    - Clinical Trials of America, Inc.
  - High Point, North Carolina, Forenede Stater, 27262
    - Peters Medical Research
  - Mooresville, North Carolina, Forenede Stater, 28117
    - Research Institute of the Carolinas, PLLC
  - Morehead City, North Carolina, Forenede Stater, 28557
    - Crystal Coast Family Practice
  - Morganton, North Carolina, Forenede Stater, 28655
    - Burke Primary Care
  - Pinehurst, North Carolina, Forenede Stater, 28374
    - Pinehurst Medical Clinic, INC.
  - Pinehurst, North Carolina, Forenede Stater, 28374
    - Pinehurst Medical Clinic. Inc.
  - Raleigh, North Carolina, Forenede Stater, 27612
    - Wake Research Associates, LLC
  - Raleigh, North Carolina, Forenede Stater, 27609
    - PMG Research of Raleigh, LLC
  - Raleigh, North Carolina, Forenede Stater, 27612
    - Wake Internal Medicine Consultants, Inc.
  - Raleigh, North Carolina, Forenede Stater, 27607
    - Blue Ridge Family Physicians, PPLC
  - Rocky Mount, North Carolina, Forenede Stater, 27804
    - Boice-Willis Clinic
  - Salisbury, North Carolina, Forenede Stater, 28144
    - PMG Research of Salisbury
  - Tabor City, North Carolina, Forenede Stater, 28463
    - Tabor City Family Medicine
  - Wilmington, North Carolina, Forenede Stater, 28401
    - PMG Research of Wilmington
  - Wilmington, North Carolina, Forenede Stater, 28401
    - PMG Research Wilmington Research Associates
  - Wilson, North Carolina, Forenede Stater, 27893
    - Natalie A. Doyle, MD PA
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Clinical Trials of America, Inc.
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Winston-Salem Health Care
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - PMG Research of Winston-Salem
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Ardmore Family Practice
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Clinical Trials of America, Inc
- North Dakota
  - Fargo, North Dakota, Forenede Stater, 58104
    - Plains Clinical Research Center
- Ohio
  - Akron, Ohio, Forenede Stater, 44313
    - Daystar Clinical Research
  - Cincinnati, Ohio, Forenede Stater, 45242
    - CFP Research, Inc.
  - Cleveland, Ohio, Forenede Stater, 44195
    - Cleveland Clinic
  - Cleveland, Ohio, Forenede Stater, 44122
    - Rapid Medical Research, Inc.
  - Columbus, Ohio, Forenede Stater, 43214
    - Riverside Methodist Hospital
  - Columbus, Ohio, Forenede Stater, 43214
    - MidWest Cardiology Research Foundation
  - Columbus, Ohio, Forenede Stater, 43210-1228
    - The Ohio State University
  - Columbus, Ohio, Forenede Stater, 43213
    - Feldman Family Practice
  - Columbus, Ohio, Forenede Stater, 43215
    - Remington-Davis Incorporated
  - Columbus, Ohio, Forenede Stater, 43228
    - Midtowne Family Practice Centre
  - Dayton, Ohio, Forenede Stater, 45419
    - PriMed Clinical Research
  - Englewood, Ohio, Forenede Stater, 45322
    - HWC Women's Research Center
  - Fairview Park, Ohio, Forenede Stater, 44126
    - Cleveland Clinic Fairview Cardiovascular Medicine
  - Franklin, Ohio, Forenede Stater, 45005
    - Prestige Clinical Research
  - Franklin, Ohio, Forenede Stater, 45005
    - Triphase Research, Ltd.
  - Gallipolis, Ohio, Forenede Stater, 45631
    - Holzer Clinic, Inc
  - London, Ohio, Forenede Stater, 43140
    - Office of Dr. Saleem Khan, MD, Inc
  - Mansfield, Ohio, Forenede Stater, 44903
    - North Central Research
  - Mansfield, Ohio, Forenede Stater, 44903
    - OhioHealth Research Institute
  - Marion, Ohio, Forenede Stater, 43302
    - R&R Research-Smith Clinic
  - Mayfield, Ohio, Forenede Stater, 44143
    - David R. Mandel, MD, Inc
  - Middleburg Heights, Ohio, Forenede Stater, 44130
    - Paramount Medical Research and Consulting, Llc
  - Newark, Ohio, Forenede Stater, 43055
    - Newark Physician Associates
  - Shaker Heights, Ohio, Forenede Stater, 44120
    - Family Medicine and Occupational Health Center, Inc.
  - Tiffin, Ohio, Forenede Stater, 44883
    - Abner Cordero, M.D.
  - Toledo, Ohio, Forenede Stater, 43608
    - Mercy St Vincent Medical Center
  - Toledo, Ohio, Forenede Stater, 43606
    - Arthritis Associates of Northwest Ohio, Inc.
  - Toledo, Ohio, Forenede Stater, 43608
    - Toledo Cardiology Consultants c/o Cardiac Research
  - Toledo, Ohio, Forenede Stater, 43614
    - South Toledo Internists
  - Toledo, Ohio, Forenede Stater, 43614
    - University of Toledo Health Science Campus
  - Toledo, Ohio, Forenede Stater, 43614
    - UT Medical Center Medicine Clinic
  - Trenton, Ohio, Forenede Stater, 45067
    - Trenton Family Medicine
  - Willoughby Hills, Ohio, Forenede Stater, 44094
    - Lake Medical Research, LLC
  - Zanesville, Ohio, Forenede Stater, 43701
    - Pharmacotherapy Research Associates Incorporated
- Oklahoma
  - Norman, Oklahoma, Forenede Stater, 73069
    - Lion Research
  - Oklahoma City, Oklahoma, Forenede Stater, 73112
    - Lynn Health Science Institute
  - Oklahoma City, Oklahoma, Forenede Stater, 73109
    - Integris Physicians Services
  - Oklahoma City, Oklahoma, Forenede Stater, 73112
    - Integris Cardiovascular Physicians LLC
  - Oklahoma City, Oklahoma, Forenede Stater, 73112
    - Integris Family Care Central
  - Oklahoma City, Oklahoma, Forenede Stater, 73112
    - Integris Physician Services
  - Tulsa, Oklahoma, Forenede Stater, 74135
    - Healthcare Research Consultants
- Oregon
  - Ashland, Oregon, Forenede Stater, 97520
    - Integrated Medical Research, PC
  - Eugene, Oregon, Forenede Stater, 97401
    - Oregon Medical Group Clinical Research
  - Eugene, Oregon, Forenede Stater, 97401
    - Lane Medical Research Group
  - Eugene, Oregon, Forenede Stater, 97401
    - Oregon Medical Group Adult Medicine Clinic
  - Medford, Oregon, Forenede Stater, 97501
    - Institute of Diabetes and Endocrinology
  - Medford, Oregon, Forenede Stater, 97504
    - Rogue Valley Physicians-Clinical Research Group
  - Portland, Oregon, Forenede Stater, 97219-1940
    - Fanno Creek Clinic
  - Portland, Oregon, Forenede Stater, 97219
    - Affinity Research
  - Portland, Oregon, Forenede Stater, 97219
    - Portland Rheumatology Clinic, Llc
  - Portland, Oregon, Forenede Stater, 97225
    - Internal Medicine Research
- Pennsylvania
  - Altoona, Pennsylvania, Forenede Stater, 16602
    - University Orthopedics Center
  - Beaver, Pennsylvania, Forenede Stater, 15009
    - Tri-State Medical Group
  - Bethlehem, Pennsylvania, Forenede Stater, 18015
    - East Penn Rheumatology Associates, Pc
  - Buckingham, Pennsylvania, Forenede Stater, 18912
    - Buckingham Family Medicine
  - Camp Hill, Pennsylvania, Forenede Stater, 17011
    - Camp Hill Clinical Research Center
  - Chicora, Pennsylvania, Forenede Stater, 16025
    - Butler Medical Associates
  - Collegeville, Pennsylvania, Forenede Stater, 19426-3626
    - Perkiomen Valley Family Practice, PC
  - Colmar, Pennsylvania, Forenede Stater, 18915
    - Rheumatology Associates, LTD
  - Connellsville, Pennsylvania, Forenede Stater, 15425
    - Office of J. Miller Oppy, MD, Youghiogheny Primary Care Practice
  - Downingtown, Pennsylvania, Forenede Stater, 19335
    - Brandywine Clinical Research
  - Duncansville, Pennsylvania, Forenede Stater, 16635
    - Altoona Center for Clinical Research
  - Erie, Pennsylvania, Forenede Stater, 16508
    - Arthritis Associates
  - Erie, Pennsylvania, Forenede Stater, 16502
    - Saint Vincent Consultant in Cardiovascular Diseases, LLC
  - Erie, Pennsylvania, Forenede Stater, 16508
    - Center For Assessment And Research Of Erie
  - Erie, Pennsylvania, Forenede Stater, 16509
    - Stan F. Slabic, M.D.
  - Feasterville, Pennsylvania, Forenede Stater, 19053
    - AMH Feasterville Family HealthCare Center
  - Greensburg, Pennsylvania, Forenede Stater, 15601
    - Westmoreland Neurology Associates, Incorporated
  - Harleysville, Pennsylvania, Forenede Stater, 19438-2513
    - Harleysville Medical Assoc
  - Harleysville, Pennsylvania, Forenede Stater, 19438
    - Lederach Family Medicine
  - Huntingdon Valley, Pennsylvania, Forenede Stater, 19006
    - Dr. Bruce Morrison, Family Practice
  - Lansdale, Pennsylvania, Forenede Stater, 19446
    - Green and Seidner Family Practice Associates
  - Lansdale, Pennsylvania, Forenede Stater, 19446
    - Detweiler Family Medicine and Associates, PC
  - Lansdale, Pennsylvania, Forenede Stater, 19446
    - Lansdale Medical Group Family Practice
  - Morrisville, Pennsylvania, Forenede Stater, 19067-5008
    - Bucks County Clinical Research
  - Norristown, Pennsylvania, Forenede Stater, 19401
    - Pearl Clinical Research, Inc.
  - Philadelphia, Pennsylvania, Forenede Stater, 19152
    - Founders Research Corporation
  - Philadelphia, Pennsylvania, Forenede Stater, 19126
    - Lehigh Wellness Center Outpatient Services
  - Pittsburgh, Pennsylvania, Forenede Stater, 15240
    - VA Pittsburgh Healthcare System
  - Pittsburgh, Pennsylvania, Forenede Stater, 15206
    - VA Pittsburgh Healthcare System
  - Red Lion, Pennsylvania, Forenede Stater, 17356
    - Dairyland Medical Center
  - Scotland, Pennsylvania, Forenede Stater, 17254
    - Sfm Clinical Trials, PC
  - Sellersville, Pennsylvania, Forenede Stater, 18960
    - Elite Medical Research, Inc.
  - Springfield, Pennsylvania, Forenede Stater, 19064
    - Prime Health Network
  - State College, Pennsylvania, Forenede Stater, 16801
    - University Orthopedics Center
  - Stoneboro, Pennsylvania, Forenede Stater, 16153
    - The Office of Dr. Joseph T. Morelli, DO
  - Tipton, Pennsylvania, Forenede Stater, 16684
    - Tipton Medical and Diagnostic Center
  - Uniontown, Pennsylvania, Forenede Stater, 15401
    - Pish Medical Associates
  - Upper Saint Clair, Pennsylvania, Forenede Stater, 15241
    - PEAK Research, LLC
  - Wexford, Pennsylvania, Forenede Stater, 15090
    - Allegheny Rheumatology - WPAHS - ASRI
  - Wyomissing, Pennsylvania, Forenede Stater, 19610
    - Clinical Research Center of Reading, LLC
  - Yardley, Pennsylvania, Forenede Stater, 19067
    - Cardiology Consultants of Philadelphia
  - Yardley, Pennsylvania, Forenede Stater, 19067
    - Jeffry A. Lindenbaum DO, PC
- Rhode Island
  - Cranston, Rhode Island, Forenede Stater, 02920
    - New England Center for Clinical Research
  - Cumberland, Rhode Island, Forenede Stater, 02864
    - Partners in Clinical Research
  - Lincoln, Rhode Island, Forenede Stater, 02865
    - Hugo M. Yamada, MD
  - Pawtucket, Rhode Island, Forenede Stater, 02860
    - Rheumatology Associates
  - Providence, Rhode Island, Forenede Stater, 02905
    - Medical Office Center
- South Carolina
  - Anderson, South Carolina, Forenede Stater, 29621
    - AnMed Health
  - Anderson, South Carolina, Forenede Stater, 29621
    - Anderson Heart
  - Charleston, South Carolina, Forenede Stater, 29406
    - Clinical Trials of South Carolina
  - Charleston, South Carolina, Forenede Stater, 29406-9333
    - Low Country Rheumatology, PA/Low Country Research Center
  - Charleston, South Carolina, Forenede Stater, 29407
    - St. Andrews Medical
  - Columbia, South Carolina, Forenede Stater, 29204
    - Medtrial
  - Columbia, South Carolina, Forenede Stater, 29201
    - Neem Research Group Inc.
  - Columbia, South Carolina, Forenede Stater, 29204
    - Columbia Arthritis Center Pa
  - Florence, South Carolina, Forenede Stater, 29501
    - Clinical Research Associates, LLC
  - Greenville, South Carolina, Forenede Stater, 29601
    - Paris View Family Practice
  - Greenville, South Carolina, Forenede Stater, 29601
    - Palmetto Clinical Trial Services, LLC
  - Greer, South Carolina, Forenede Stater, 29651
    - Mountain View Clinical Research, Inc.
  - Greer, South Carolina, Forenede Stater, 29651
    - DeGarmo Institute of Medical Research
  - Greer, South Carolina, Forenede Stater, 29650
    - Radiant Research, Inc
  - Greer, South Carolina, Forenede Stater, 29650
    - John Milas
  - Laurens, South Carolina, Forenede Stater, 29360
    - Palmetto Clinical Trial Services, LLC at the Family Healthcare Center
  - Moncks Corner, South Carolina, Forenede Stater, 29461
    - Berkeley Medical Center
  - Mount Pleasant, South Carolina, Forenede Stater, 29464
    - PMG Research of Charleston
  - North Myrtle Beach, South Carolina, Forenede Stater, 29582
    - North Myrtle Beach Family Practice
  - Orangeburg, South Carolina, Forenede Stater, 29115-4931
    - Coulter Clinic
  - Orangeburg, South Carolina, Forenede Stater, 29118
    - Orangeburg Medical Associates, PA
  - Rock Hill, South Carolina, Forenede Stater, 29732
    - The Carolina Center for Rheumatology & Arthritis Care, PA
  - Simpsonville, South Carolina, Forenede Stater, 29681
    - Hillcrest Clinical Research, LLC
  - Simpsonville, South Carolina, Forenede Stater, 29681
    - Hillcrest Family Practice
  - Spartanburg, South Carolina, Forenede Stater, 29302
    - Palmetto Research
  - Summerville, South Carolina, Forenede Stater, 29485
    - Palmetto Clinical Research
  - Taylors, South Carolina, Forenede Stater, 29687
    - Southeastern Research Associates, Inc.
- South Dakota
  - Aberdeen, South Dakota, Forenede Stater, 57401
    - Odyssey Research/Sanford Clinic - Aberdeen
  - Aberdeen, South Dakota, Forenede Stater, 57401
    - Sanford Clinic - Aberdeen
  - Rapid City, South Dakota, Forenede Stater, 57702
    - Health Concepts
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Regional Health Clinic Research
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Regional Medical Clinic-Rheumatology
  - Watertown, South Dakota, Forenede Stater, 57201
    - Brown Clinic PLLP
  - Watertown, South Dakota, Forenede Stater, 57201
    - Odyssey Research
- Tennessee
  - Bristol, Tennessee, Forenede Stater, 37620
    - Holston Medical Group
  - Bristol, Tennessee, Forenede Stater, 37620
    - Pmg Research of Bristol
  - Bristol, Tennessee, Forenede Stater, 37620
    - Internal Medicine & Pediatric Associates of Bristol
  - Fayetteville, Tennessee, Forenede Stater, 37334
    - Parkway Medical Group
  - Germantown, Tennessee, Forenede Stater, 38138
    - Stern Cardiovascular Foundation, Inc.
  - Jackson, Tennessee, Forenede Stater, 38305
    - Arthritis Clinic
  - Jackson, Tennessee, Forenede Stater, 38305
    - The Jackson Clinic, PA
  - Johnson City, Tennessee, Forenede Stater, 37604
    - State of Franklin Healthcare Associates Clinical Research
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Holston Medical Group
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Holston Valley Surgery Center
  - Memphis, Tennessee, Forenede Stater, 38119-5214
    - Gupta, Ramesh C MD
  - Nashville, Tennessee, Forenede Stater, 37205
    - Nashville Medical Research Institute
  - Nashville, Tennessee, Forenede Stater, 37211
    - Quality Medical Research
  - Nashville, Tennessee, Forenede Stater, 37203
    - Access Clinical Trials, Inc.
  - Nashville, Tennessee, Forenede Stater, 37203
    - Premier Orthopaedics
  - Nashville, Tennessee, Forenede Stater, 37203
    - The Cholesterol Center of Nashville
- Texas
  - Amarillo, Texas, Forenede Stater, 79106
    - Amarillo Medical Specialists, LLP
  - Amarillo, Texas, Forenede Stater, 79106
    - Pharma Tex Research, LLC
  - Arlington, Texas, Forenede Stater, 76013
    - Family Health Care Association
  - Arlington, Texas, Forenede Stater, 76017
    - South Arlington Primary Care Associates PA
  - Arlington, Texas, Forenede Stater, 76018
    - DCT - Anchor, LLC dba Discovery Clinical Trials
  - Austin, Texas, Forenede Stater, 78758
    - DCT-AACT, LLC dba Discovery Clinical Trials
  - Beaumont, Texas, Forenede Stater, 77702
    - Southeast Texas Clinical Research Center
  - Beaumont, Texas, Forenede Stater, 77702
    - Southeast Texas Cardiology Associates
  - Bedford, Texas, Forenede Stater, 76021
    - Kaner Medical Group PA
  - Bedford, Texas, Forenede Stater, 76021
    - Nexxus Research Group, LLC
  - Bedford, Texas, Forenede Stater, 76021
    - Texas Orthopedic Specialists, PLLC
  - Carrollton, Texas, Forenede Stater, 75007
    - MedicalEdge Healthcare Group, PA, dba Leading Edge Research, PA
  - Colleyville, Texas, Forenede Stater, 76034
    - Prentiss Family Medicine
  - Corpus Christi, Texas, Forenede Stater, 78405
    - Carlos B. Everett, MD
  - Corpus Christi, Texas, Forenede Stater, 78411
    - Discovery Clinical Research
  - Dallas, Texas, Forenede Stater, 75231
    - Metroplex Clinical Research Center
  - Dallas, Texas, Forenede Stater, 75220
    - Texas Health Physicians Group
  - Dallas, Texas, Forenede Stater, 75226
    - Soltero Cardiovascular Research Center/Baylor University Medical Center
  - Dallas, Texas, Forenede Stater, 75231
    - Arthritis Care And Diagnostic Center, P.A.
  - Dallas, Texas, Forenede Stater, 75231
    - Medical Specialists Associated
  - Dallas, Texas, Forenede Stater, 75231
    - Southwest Rheumatology, P.A.
  - Dallas, Texas, Forenede Stater, 75254
    - DCT - Genesis Neighborhood Research, LLC dba Discovery Clinical Trials
  - El Paso, Texas, Forenede Stater, 79902
    - Rajendra K. Marwah, MD
  - Euless, Texas, Forenede Stater, 76039
    - Kaner Medical Group, PA
  - Fort Worth, Texas, Forenede Stater, 76104
    - The Medical Group Of Texas
  - Fort Worth, Texas, Forenede Stater, 76107
    - Texas Health Physicians Group
  - Fort Worth, Texas, Forenede Stater, 76117
    - T & R Clinic, P. A.
  - Galveston, Texas, Forenede Stater, 77555
    - Rheumatology-UTMB
  - Garland, Texas, Forenede Stater, 75041
    - Towngate Plaza Medical Center
  - Grand Prairie, Texas, Forenede Stater, 75052
    - ProCare Clinical Trials
  - Houston, Texas, Forenede Stater, 77008
    - Salim Gopalani, MD, PA
  - Houston, Texas, Forenede Stater, 77024
    - Village Family Practice
  - Houston, Texas, Forenede Stater, 77004
    - The Office of Amer Zaheer MD, PA
  - Houston, Texas, Forenede Stater, 77024
    - Office of Cyril Wolf, MD
  - Houston, Texas, Forenede Stater, 77025-1669
    - Kelsey Seybold Clinic
  - Houston, Texas, Forenede Stater, 77074
    - Oxford Clinical Research, LLC
  - Houston, Texas, Forenede Stater, 77079
    - MCA Research
  - Irving, Texas, Forenede Stater, 75039
    - Texas Health Physicians Group
  - Lewisville, Texas, Forenede Stater, 75057
    - One World Medical Associates, P.A.
  - Lewisville, Texas, Forenede Stater, 75067
    - Pri-Med Care
  - McAllen, Texas, Forenede Stater, 78501
    - South Texas Institute of Health
  - McKinney, Texas, Forenede Stater, 75071
    - DCT - Genesis Seidmeyer Research, LLC dba Discovery Clinical Trials
  - Mesquite, Texas, Forenede Stater, 75150
    - Southwest Rheumatology, PA
  - Midland, Texas, Forenede Stater, 79707
    - Midland Clinical Research Center
  - Odessa, Texas, Forenede Stater, 79761
    - Permian Research Foundation
  - Odessa, Texas, Forenede Stater, 79761
    - Basin Orthopedics Surgical Specialists
  - Odessa, Texas, Forenede Stater, 79761
    - Center for Hypertension and Internal Medicine
  - Odessa, Texas, Forenede Stater, 79761
    - Odessa Heart Institute
  - Pasadena, Texas, Forenede Stater, 77504
    - Office of David K. McDonald, M.D.. P.A.
  - Pharr, Texas, Forenede Stater, 78577-5198
    - Centex Studies, Inc.
  - Plano, Texas, Forenede Stater, 75075
    - Clinical Investigations of Texas, LLC
  - Plano, Texas, Forenede Stater, 75093
    - North Texas Medical Research
  - Plano, Texas, Forenede Stater, 75075
    - DCT-Genesis naini, LLC dba Discovery Clinical Trials
  - Richardson, Texas, Forenede Stater, 75080
    - MedicalEdge Healthcare Group, PA
  - Richardson, Texas, Forenede Stater, 75080
    - Texas Health Physicians Group
  - Richmond, Texas, Forenede Stater, 77469
    - Ivan N. Mefford, MD, PhD, PA
  - San Antonio, Texas, Forenede Stater, 78215
    - Sun Research Institute
  - San Antonio, Texas, Forenede Stater, 78229
    - S.A.M. Clinical Research Center
  - San Antonio, Texas, Forenede Stater, 78213
    - Gsa Research
  - San Antonio, Texas, Forenede Stater, 78209
    - Quality Research Inc.
  - San Antonio, Texas, Forenede Stater, 78217
    - Radiant Research San Antonio Northeast
  - San Antonio, Texas, Forenede Stater, 78205
    - Paragon Research Center, LLC
  - San Antonio, Texas, Forenede Stater, 78224
    - Briggs Clinical Research, LLC
  - San Antonio, Texas, Forenede Stater, 78207
    - Quality Assurance Research Center
  - San Antonio, Texas, Forenede Stater, 78212
    - Physician PrimeCare Research Institute, PLLC dba Health Texas Research Institute
  - San Antonio, Texas, Forenede Stater, 78224
    - DCT - Barlite, LLC dba Discovery Clinical Trials
  - San Antonio, Texas, Forenede Stater, 78229
    - Wellmed Clinical Research
  - San Antonio, Texas, Forenede Stater, 78251
    - DCT-Westover Hills, LLC dba Discovery Clinical Trials
  - San Antonio, Texas, Forenede Stater, 78258
    - DCT - Stone Oak, LLC dba Discovery Clinical Trials
  - San Antonio, Texas, Forenede Stater, 78258
    - The Office of Shahbaz Yazdani, MD, PA
  - Southlake, Texas, Forenede Stater, 76092
    - Southlake Clinical Trials
  - Sugar Land, Texas, Forenede Stater, 77479
    - Sugar Land Med-Ped Clinic, PA
  - Victoria, Texas, Forenede Stater, 77901
    - Crossroads Clinical Research
  - Victoria, Texas, Forenede Stater, 77901
    - Crossroads Clinical Research, LLC
  - Webster, Texas, Forenede Stater, 77598
    - Office of Pamela Dugano-Daphnis
- Utah
  - Ogden, Utah, Forenede Stater, 84405
    - Advanced Research Institute
  - West Jordan, Utah, Forenede Stater, 84088
    - Advanced Clinical Research
- Virginia
  - Burke, Virginia, Forenede Stater, 22015
    - Burke Internal Medicine & Research
  - Burke, Virginia, Forenede Stater, 22015
    - Burke Internal Medicine
  - Chesapeake, Virginia, Forenede Stater, 23320-4985
    - Center for Arthritis and Rheumatic Diseases
  - Chesapeake, Virginia, Forenede Stater, 23320
    - Bayview Physicians oa Cardiovascular Associates, Ltd
  - Chesapeake, Virginia, Forenede Stater, 23320
    - David Ramstad, MD, MPH and Associates
  - Danville, Virginia, Forenede Stater, 24541
    - Danville Internal Medicine, Inc.
  - Danville, Virginia, Forenede Stater, 24541
    - Danville Orthopedic Clinic
  - Falls Church, Virginia, Forenede Stater, 22044
    - Seven Corners Medical Research Center
  - Hampton, Virginia, Forenede Stater, 23666
    - Hampton Family Practice
  - Manassas, Virginia, Forenede Stater, 20110
    - Manassas Clinical Research Center
  - Newport News, Virginia, Forenede Stater, 23601
    - Bruton Avenue Family Practice
  - Norfolk, Virginia, Forenede Stater, 23502
    - Internal Medicine Kidney and Hypertension Center
  - Norfolk, Virginia, Forenede Stater, 23502
    - Sentara Medical Group
  - Norfolk, Virginia, Forenede Stater, 23502
    - National Clinical Research - Norfolk Inc.
  - Petersburg, Virginia, Forenede Stater, 23803
    - Ettrick Health Center
  - Portsmouth, Virginia, Forenede Stater, 23701
    - Arthritis and Rheumatic Research
  - Roanoke, Virginia, Forenede Stater, 24014
    - Roanoke Heart Institute
  - Suffolk, Virginia, Forenede Stater, 23435
    - Harbourview Professional Center
  - Virginia Beach, Virginia, Forenede Stater, 23452
    - Chase Research Group, LLC
  - Williamsburg, Virginia, Forenede Stater, 23185
    - The Center for Excellence in Aging and Geriatric Health
- Washington
  - Burien, Washington, Forenede Stater, 98166
    - Highline Medical Center Laboratory
  - Seattle, Washington, Forenede Stater, 98144
    - Puget Sound Osteoporosis Center
  - Seattle, Washington, Forenede Stater, 98166-2967
    - Arthritis Northwest
  - Spokane, Washington, Forenede Stater, 99204
    - Arthritis Northwest Rheumatology
  - Spokane, Washington, Forenede Stater, 99204
    - Lawrence S. Eastburn, MD, PS
  - Spokane, Washington, Forenede Stater, 99204
    - Pulmonary and Research Associates
  - Spokane, Washington, Forenede Stater, 99216
    - The Office of William Gray, Md, Family Practice
  - Spokane, Washington, Forenede Stater, 99218
    - John F. Long, D.O.
  - Tacoma, Washington, Forenede Stater, 98405
    - Tacoma Center for Arthritis Research, PS
  - Tacoma, Washington, Forenede Stater, 98405
    - George H. Krick, MD
  - Tacoma, Washington, Forenede Stater, 98405
    - Northwest Family and Spinal Clinic
  - Tacoma, Washington, Forenede Stater, 98405
    - Rheumatology Infusion Services
  - Wenatchee, Washington, Forenede Stater, 98801
    - Wenatchee Valley Medical Center, Research Department
  - Yakima, Washington, Forenede Stater, 98902
    - Clinical Trials Northwest
- West Virginia
  - Beckley, West Virginia, Forenede Stater, 25801
    - Rheumatology and Pulmonary Clinic
  - Clarksburg, West Virginia, Forenede Stater, 26301
    - Mountain State Clinical Research
  - Huntington, West Virginia, Forenede Stater, 25701
    - University Cardiovascular Services. Robert C. Byrd Clinical Center
  - Lewisburg, West Virginia, Forenede Stater, 24901
    - WVVA Healthcare Alliance
  - Parkersburg, West Virginia, Forenede Stater, 26101
    - Parkersburg Cardiology Associates
- Wisconsin
  - Madison, Wisconsin, Forenede Stater, 53713
    - Meriter Medical Group
  - Madison, Wisconsin, Forenede Stater, 53715
    - University of Wisconsin School of Medicine and Public Health
  - Madison, Wisconsin, Forenede Stater, 53715
    - UW Health Physicians
  - Milwaukee, Wisconsin, Forenede Stater, 53295
    - Zablocki VA Medical Center
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - St. Lukes Pain Management Center
  - Rhinelander, Wisconsin, Forenede Stater, 54501
    - Aspirus Cardiovascular Associates - Rhinelander
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Aspirus Wausau Hospital
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Aspirus Cardiovascular Associates
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Aspirus Heart & Vascular lnstitute--Research & Education)
  - Wauwatosa, Wisconsin, Forenede Stater, 53226
    - Allegiance Research Specialists, LLC
Hong Kong
- - Pokfulam, Hong Kong
    - Department of Medicine, Queen Mary Hospital
  - Sheung Shui, NT, Hong Kong
    - Department of Medicine, North District Hospital
- NEW Territories
  - Shatin, NEW Territories, Hong Kong
    - Prince of Wales Hospital
- NT
  - New Territories, NT, Hong Kong
    - Centre for Assessment and Treatment of Rheumatic Diseases, Department of Medicine and Geriatrics
Mexico
- - Mexico City, Mexico, 03300
    - Clinicos Asociados Bocm, S.C.
- BAJA California
  - Tijuana, BAJA California, Mexico, 22010
    - Centro de Investigacion del Noroeste SC
- D.f.
  - Mexico, D.f., Mexico, 06100
    - Comite Mexicano para la Prevencion de la Osteoporosis, A.C.
  - Mexico, D.f., Mexico, 06700
    - Instituto Mexicano de Investigación Clínica, S.A. de C.V
- DF
  - Mexico, DF, Mexico, 14050
    - CIF-BIOTEC, Medica Sur
- Estado DE Mexico
  - Metepec, Estado DE Mexico, Mexico, 52140
    - Centro Medico Toluca
- Guanajuato
  - Leon, Guanajuato, Mexico, 37520
    - Hospital Regional ISSSTE
- Jalisco
  - Guadalajara, Jalisco, Mexico, 44690
    - Centro de Estudios de Investigacion Basica y Clinica SC.
  - Guadalajara, Jalisco, Mexico, 44160
    - Instituto Jalisciense de Investigación Clínica Sa de Cv
- Michoacan
  - Morelia, Michoacan, Mexico, 58000
    - Unidad de Investigacion Dr. Mario Alvizouri Muñoz Ac Del Hospital General Dr. Miguel Silva
- SLP
  - San Luis Potosi, SLP, Mexico, 78240
    - Hospital Central "Dr. Ignacio Morones Prieto" Unidad Regional de Reumatologia y Osteoporosis
Panama
- - Panama City, Panama
    - Centro de Investigacion Marbella
Peru
- - Lima, Peru, 11
    - Clinica San Felipe
  - Lima, Peru, L29
    - Centro de Investigaciones Medical
  - Lima, Peru, Lima 36
    - Clinica San Juan Bautista
- Lima
  - San Isidro, Lima, Peru, L 27
    - IPC - Centro de Salud Integral S.A.
  - Santiago de Surco, Lima, Peru, 00033
    - Centro Empresarial - Altavista Polo 4
  - Santiago de Surco, Lima, Peru, 00033
    - Instituto de Ginecología y Reproducción & Cirugía Mínimamente Invasiva
Taiwan
- - Chia-Yi County, Taiwan, 62247
    - Buddhist Tzu Chi Dailin General Hospital
  - Kaohsiung, Taiwan, 807
    - Chung-Ho Memorial Hospital, Kaoshiung Medical University Hospital
  - Taichung, Taiwan, 40705
    - Taichung Veterans General Hospital
  - Taichung, Taiwan, 402
    - Chung Shan Medical University Hospital
  - Taipei, Taiwan, 112
    - Taipei Veterans General Hospital
  - Taipei, Taiwan, 10018
    - National Taiwan University Hospital
  - Taipei City, Taiwan, 100
    - Tri-Service General Hospital
- Kaohsiung County
  - Nio Sung Township, Kaohsiung County, Taiwan, 833
    - Chang Gung Memorial Hospital-Kaohsiung branch, Section of Allergy, Immunology
- Taipei CITY
  - Neihu District, Taipei CITY, Taiwan, 114
    - Tri-Service General Hospital
- Taoyuan County
  - Gueishan Township, Taoyuan County, Taiwan, 333
    - Chang Gung Medical Foundation-Linkou Branch
- Yung Kang
  - Tainan, Yung Kang, Taiwan, 71004
    - Chi-Mei Medical Center
Ukraine
- - Chernivtsi, Ukraine, 58022
    - Municipal Medical Institution "City Clinical Hospital #3", Department of Rheumatology
  - Dnipropetrovsk, Ukraine, 49005
    - MI Dnipropetrovsk Regional Clinical Hospital named after I.I Mechnikov
  - Dnipropetrovsk, Ukraine, 49005
    - State Institution "Dnipropetrovsk Medical Academy of MOH, Ukraine
  - Donetsk, Ukraine, 83001
    - Rheumatology Department, MMI "City Clinical Hospital #5", DNMU n.a. M.Gorkyy,
  - Donetsk, Ukraine, 83003
    - Donetsk National Med University, Chair of Propaedeutics and Internal Medicine
  - Kharkiv, Ukraine, 61002
    - Municipal Establishment of Health Care
  - Kharkiv, Ukraine, 61178
    - City Clinical Hospital # 8, Dept of Cardiology and Functional Diagnostics
  - Kyiv, Ukraine, 02091
    - City Clinical Hospital #1
  - Kyiv, Ukraine, 03680
    - National Scientific Center "The Strazhesko Institute of Cardiology"
  - Kyiv, Ukraine, 04053
    - State Institution "Republican clinical hospital of MOH of Ukraine"
  - Kyiv, Ukraine, 04107
    - Family Medicine Department of NMAPE named after PL Shupyk,
  - Lutsk, Ukraine, 43024
    - Lutsk City Clinical Hospital
  - Lviv, Ukraine, 79013
    - Municipal City Clinical Hospital #5
  - Odesa, Ukraine, 65009
    - Center of Reconstructive and Regenerative Medicine (University clinic) of
  - Ternopil, Ukraine, 46010
    - Treatment-and-Diagnostic Center LLC "Desna" Ltd
  - Zaporizhzhia, Ukraine, 69118
    - Municipal enterprise " City Hospital # 7",
  - Zaporizhzhya, Ukraine, 69065
    - Municipal Institution "Zaporizhzhya City Multiple Discipline Clinical Hospital #9"
  - Zhytomyr, Ukraine, 10003
    - Zhytomyr Regional Clinical Hospital n.a. O.F. Gerbachevs'kyy/ Rheumatology Center
- Crimea
  - Simferopol, Crimea, Ukraine, 95017
    - CRI "Clinical Territorial Medical Association "University Clinic",

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inklusionskriterier:

Forsøgspersoner med slidgigt eller leddegigt med eller i risiko for at udvikle hjerte-kar-sygdom, og som har behov for og berettiget til kronisk, daglig behandling med et NSAID for at kontrollere arthritis tegn og symptomer.

Ekskluderingskriterier:

Forsøgspersoner har haft en nylig kardiovaskulær hændelse, ustabile kardiovaskulære tilstande eller enhver større operation (hjerte eller ikke-kardial) inden for 3 måneder før randomisering;
Forsøgspersoner med medicinske eller laboratoriemæssige abnormiteter, der ville gøre forsøgspersonen uegnet til at deltage i dette forsøg
Forsøgspersoner kræver behandling med aspirin > 325 mg/dag
Personer med kendt overfølsomhed over for celecoxib, ibuprofen, naproxen, aspirin eller esomeprazol mv.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Tredobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: celecoxib forsøgspersonen får celecoxib og dummy (placebo) ibuprofen og naproxen	Medicin: celecoxib 100 til 200 mg to gange dagligt, taget gennem munden
Aktiv komparator: ibuprofen forsøgspersonen får ibuprofen og dummy (placebo) celecoxib og naproxen	Medicin: Ibuprofen ibuprofen 600 mg til 800 mg tre gange dagligt, taget gennem munden
Aktiv komparator: naproxen forsøgspersonen får naproxen og dummy (placebo) celecoxib og ibuprofen	Medicin: Naproxen naproxen 375 mg til 500 mg to gange dagligt, taget gennem munden

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Den første forekomst af antiplatelet trialists Collaboration (APTC) Composite Endpoint, bekræftet af Clinical Events Committee (CEC). Tidsramme: Intent to Treat (ITT) Befolkning - 30 måneder; Modificeret ITT (MITT) Befolkning - 42 måneder	APTC-hændelser defineres som en sammensætning af en af følgende hændelser: Dødsfald på grund af CV-årsager (inklusive hjerte-, cerebrovaskulær, venøs tromboembolisk, hæmoragisk, anden vaskulær eller ukendt årsag); Ikke-dødelig MI; Ikke-dødelig slagtilfælde (herunder intrakranielle blødninger, slagtilfælde af iskæmisk eller ukendt ætiologi).	Intent to Treat (ITT) Befolkning - 30 måneder; Modificeret ITT (MITT) Befolkning - 42 måneder

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Den første forekomst af større uønskede kardiovaskulære hændelser (MACE) Tidsramme: ITT-befolkning - 30 måneder; MITT Befolkning - 42 måneder	MACE defineret som sammensætningen af CV-død (herunder hæmoragisk død), ikke-dødelig MI, ikke-dødelig slagtilfælde, hospitalsindlæggelse for UA, revaskularisering eller hospitalsindlæggelse for TIA	ITT-befolkning - 30 måneder; MITT Befolkning - 42 måneder
Den første forekomst af klinisk signifikante gastrointestinale hændelser (CSGIE) Tidsramme: ITT-befolkning - 30 måneder; MITT Befolkning - 42 måneder	CSGIE inkluderer: Gastroduodenal (GD) blødning, maveudløbsobstruktion, gastroduodenal, tyndtarm eller tyktarmsperforation, tyktarmsblødning, tyndtarmsblødning, akut GI-blødning af ukendt oprindelse, inklusive formodet tyndtarmsblødning, symptomatisk mavesår eller duodenal	ITT-befolkning - 30 måneder; MITT Befolkning - 42 måneder
Ændring fra baseline i patientens vurdering af arthritissmerter (VAS) Tidsramme: ITT og MITT Population - Baseline til 42 måneder	VAS-spørgsmålet "Hvor meget smerter har du" blev bedømt på en skala fra 0 til 100, hvor 0 angiver "Ingen smerte" og 100 angiver "Værst mulige smerter".	ITT og MITT Population - Baseline til 42 måneder

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Samarbejdspartnere

The Cleveland Clinic

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Hjælpsomme links

To obtain contact information for a study center near you, click here.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

4. oktober 2006

Primær færdiggørelse (Faktiske)

12. april 2016

Studieafslutning (Faktiske)

12. april 2016

Datoer for studieregistrering

Først indsendt

28. juni 2006

Først indsendt, der opfyldte QC-kriterier

28. juni 2006

Først opslået (Skøn)

29. juni 2006

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

3. marts 2021

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

1. marts 2021

Sidst verificeret

1. marts 2021

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

A3191172
2004-002441-13 (EudraCT nummer)
PRECISION TRIAL (Anden identifikator: Alias Study Number)

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Prospektiv randomiseret evaluering af Celecoxib Integrated Safety vs Ibuprofen eller Naproxen (PRECISION)

En randomiseret, dobbeltblind, parallelgruppeundersøgelse af kardiovaskulær sikkerhed hos patienter med slidgigt eller leddegigt med eller i høj risiko for hjertekarsygdomme, der sammenligner Celecoxib med Naproxen og Ibuprofen

Studieoversigt

Status

Betingelser

Intervention / Behandling

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Samarbejdspartnere

Publikationer og nyttige links

Generelle publikationer

Hjælpsomme links

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Faktiske)

Studieafslutning (Faktiske)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Skøn)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre