Indsamling og opbevaring af blod, knoglemarv og andre prøver fra patienter med akut leukæmi, kronisk leukæmi eller myelodysplastisk syndrom
30. juli 2024 opdateret af: Alliance for Clinical Trials in Oncology
CALGB-leukæmivævsbanken
Som en af landets største kooperative kræftbehandlingsgrupper er Alliance for Clinical Trials in Oncology (Alliance) i en unik position til at organisere en leukæmivævsbank.
Medlemsinstitutionerne diagnosticerer hvert år hundredvis af patienter med leukæmi eller myelodysplastisk syndrom og behandler disse patienter ensartet med kemoterapi.
Alliancen tilbyder centraliseret datastyring for den kliniske historie, klassificering af leukæmi og myelodysplastisk syndrom, cytogenetik, flowcytometrisk analyse, behandling og opfølgning.
De højtuddannede sundhedsudbydere på hver medlemsinstitution er fortrolige med at indhente informeret samtykke, udfylde dataspørgeskemaer og sende prøver.
Der eksisterer i øjeblikket en central behandlingsfacilitet, hvor prøver fremstilles til en række forskellige cellulære og molekylære undersøgelser.
Derfor er patientressourcerne, sundhedsudbyderne og en behandlingsfacilitet til en leukæmivævsbank alle på plads.
Hvad der imidlertid er behov for, og som behandles i den nuværende protokol, er en formel mekanisme til at fremskaffe knoglemarv, blod og normalt væv fra patienter med hæmatologiske maligniteter, som skal tilmeldes Alliance (Cancer og Leukæmi Gruppe B [CALGB]) behandling undersøgelser.
Studieoversigt
Status
Aktiv, ikke rekrutterende
Betingelser
Intervention / Behandling
Detaljeret beskrivelse
Formålet med undersøgelsen er at indsamle og opbevare prøver fra hver nydiagnosticeret patient med akut eller kronisk leukæmi eller myelodysplastisk syndrom (MDS), som er optaget på en CALGB-protokol for tidligere ubehandlede patienter. Knoglemarvsaspirat- og blodprøver udtages fra patienter ved diagnose, remission eller tilbagefald og opbevares. Buccale smears opnås ved diagnose, og DNA ekstraheres og konserveres.
Det var forventet, at prøverne indsamlet under denne protokol ville blive brugt af et stort antal efterforskere. Denne protokol beskriver ikke detaljerne for hvert godkendt projekt (f.eks. aldersgruppe for støtteberettigelse).
Undersøgelsestype
Observationel
Tilmelding (Anslået)
1500
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
-
-
California
-
Mountain View, California, Forenede Stater, 94040
- Camino Medical Group - Treatment Center
-
Pismo Beach, California, Forenede Stater, 93449
-
San Diego, California, Forenede Stater, 92134
- Naval Medical Center - San Diego
-
San Francisco, California, Forenede Stater, 94115
- UCSF Helen Diller Family Comprehensive Cancer Center
-
-
Connecticut
-
Hartford, Connecticut, Forenede Stater, 06102-5037
- Helen and Harry Gray Cancer Center at Hartford Hospital
-
-
Delaware
-
Lewes, Delaware, Forenede Stater, 19958
- Tunnell Cancer Center at Beebe Medical Center
-
Newark, Delaware, Forenede Stater, 19713
- CCOP - Christiana Care Health Services
-
-
District of Columbia
-
Washington, District of Columbia, Forenede Stater, 20007
- Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
-
Washington, District of Columbia, Forenede Stater, 20010
- Washington Cancer Institute at Washington Hospital Center
-
-
Florida
-
Fort Lauderdale, Florida, Forenede Stater, 33308
- Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
-
Jupiter, Florida, Forenede Stater, 33458
- Ella Milbank Foshay Cancer Center at Jupiter Medical Center
-
Miami Beach, Florida, Forenede Stater, 33140
- CCOP - Mount Sinai Medical Center
-
Orlando, Florida, Forenede Stater, 32803-1273
- Florida Hospital Cancer Institute at Florida Hospital Orlando
-
-
Illinois
-
Bloomington, Illinois, Forenede Stater, 61701
- Illinois CancerCare - Bloomington
-
Bloomington, Illinois, Forenede Stater, 61701
- St. Joseph Medical Center
-
Canton, Illinois, Forenede Stater, 61520
- Illinois CancerCare - Canton
-
Chicago, Illinois, Forenede Stater, 60637-1470
- University of Chicago Cancer Research Center
-
Chicago, Illinois, Forenede Stater, 60612-7243
- University of Illinois Cancer Center
-
Chicago, Illinois, Forenede Stater, 60612
- Veterans Affairs Medical Center - Chicago Westside Hospital
-
Eureka, Illinois, Forenede Stater, 61530
- Illinois CancerCare - Eureka
-
Eureka, Illinois, Forenede Stater, 61530
- Eureka Community Hospital
-
Evanston, Illinois, Forenede Stater, 60201-1781
- Evanston Hospital
-
Galesburg, Illinois, Forenede Stater, 61401
- Galesburg Clinic, PC
-
Macomb, Illinois, Forenede Stater, 61455
- Illinois CancerCare - Macomb
-
Normal, Illinois, Forenede Stater, 61761
- Bromenn Regional Medical Center
-
Normal, Illinois, Forenede Stater, 61761
- Community Cancer Center
-
Normal, Illinois, Forenede Stater, 61761
- Illinois CancerCare - Community Cancer Center
-
Ottawa, Illinois, Forenede Stater, 61350
- Community Hospital of Ottawa
-
Ottawa, Illinois, Forenede Stater, 61350
- Oncology Hematology Associates of Central Illinois, PC - Ottawa
-
Pekin, Illinois, Forenede Stater, 61554
- Cancer Treatment Center at Pekin Hospital
-
Pekin, Illinois, Forenede Stater, 61603
- Illinois CancerCare - Pekin
-
Peoria, Illinois, Forenede Stater, 61636
- Methodist Medical Center of Illinois
-
Peoria, Illinois, Forenede Stater, 61614
- Proctor Hospital
-
Peoria, Illinois, Forenede Stater, 61637
- OSF St. Francis Medical Center
-
Peoria, Illinois, Forenede Stater, 61615
- CCOP - Illinois Oncology Research Association
-
Peoria, Illinois, Forenede Stater, 61615
- Oncology Hematology Associates of Central Illinois, PC - Peoria
-
Peru, Illinois, Forenede Stater, 61354
- Illinois CancerCare - Peru
-
Peru, Illinois, Forenede Stater, 61354
- Illinois Valley Community Hospital
-
Spring Valley, Illinois, Forenede Stater, 61362
- Illinois CancerCare - Spring Valley
-
-
Indiana
-
Elkhart, Indiana, Forenede Stater, 46515
- Elkhart General Hospital
-
Elkhart, Indiana, Forenede Stater, 46514-2098
- Elkhart Clinic, LLC
-
Elkhart, Indiana, Forenede Stater, 46514
- Michiana Hematology-Oncology, PC - Elkhart
-
Kokomo, Indiana, Forenede Stater, 46904
- Howard Community Hospital
-
La Porte, Indiana, Forenede Stater, 46350
- Center for Cancer Therapy at LaPorte Hospital and Health Services
-
Merrillville, Indiana, Forenede Stater, 46410
- Suniti Medical Corporation
-
Mishawaka, Indiana, Forenede Stater, 46545-1470
- Michiana Hematology-Oncology, PC - South Bend
-
Mishawaka, Indiana, Forenede Stater, 46545-1470
- Saint Joseph Regional Medical Center
-
Plymouth, Indiana, Forenede Stater, 46563
- Michiana Hematology Oncology PC - Plymouth
-
South Bend, Indiana, Forenede Stater, 46601
- Memorial Hospital of South Bend
-
South Bend, Indiana, Forenede Stater, 46601
- CCOP - Northern Indiana CR Consortium
-
Westville, Indiana, Forenede Stater, 46391
- Michiana Hematology Oncology PC - La Porte
-
-
Iowa
-
Bettendorf, Iowa, Forenede Stater, 52722
- Hematology Oncology Associates of the Quad Cities
-
Cedar Rapids, Iowa, Forenede Stater, 52402
- Iowa Blood and Cancer Care
-
Iowa City, Iowa, Forenede Stater, 52242-1002
- Holden Comprehensive Cancer Center at University of Iowa
-
Iowa City, Iowa, Forenede Stater, 52246
- Veterans Affairs Medical Center - Iowa City
-
-
Kansas
-
Overland Park, Kansas, Forenede Stater, 66209
- Menorah Medical Center
-
Overland Park, Kansas, Forenede Stater, 66213
- Saint Luke's Hospital - South
-
Prairie Village, Kansas, Forenede Stater, 66208
- CCOP - Kansas City
-
-
Maine
-
Augusta, Maine, Forenede Stater, 04330
- Harold Alfond Center for Cancer Care
-
Bangor, Maine, Forenede Stater, 04401
- CancerCare of Maine at Eastern Maine Medical Center
-
-
Maryland
-
Baltimore, Maryland, Forenede Stater, 21201
- Greenebaum Cancer Center at University of Maryland Medical Center
-
Bethesda, Maryland, Forenede Stater, 20889-5600
- National Naval Medical Center
-
Elkton, Maryland, Forenede Stater, 21921
- Union Hospital of Cecil County
-
-
Massachusetts
-
Boston, Massachusetts, Forenede Stater, 02114
- Massachusetts General Hospital
-
Boston, Massachusetts, Forenede Stater, 02115
- Dana-Farber/Brigham and Women's Cancer Center
-
Boston, Massachusetts, Forenede Stater, 02115
- Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute
-
Gloucester, Massachusetts, Forenede Stater, 01930
- Addison Gilbert Hospital
-
-
Michigan
-
Saint Joseph, Michigan, Forenede Stater, 49085
- Lakeside Cancer Specialists, PLLC
-
Saint Joseph, Michigan, Forenede Stater, 49085
- Lakeland Regional Cancer Care Center - St. Joseph
-
-
Minnesota
-
Duluth, Minnesota, Forenede Stater, 55805
- St. Luke's Hospital Cancer Care Center
-
Minneapolis, Minnesota, Forenede Stater, 55417
- Veterans Affairs Medical Center - Minneapolis
-
Minneapolis, Minnesota, Forenede Stater, 55455
- Masonic Cancer Center at University of Minnesota
-
-
Missouri
-
Cape Girardeau, Missouri, Forenede Stater, 63703
- Southeast Cancer Center
-
Columbia, Missouri, Forenede Stater, 65203
- Ellis Fischel Cancer Center at University of Missouri - Columbia
-
Jefferson City, Missouri, Forenede Stater, 65109
- Goldschmidt Cancer Center
-
Kansas City, Missouri, Forenede Stater, 64116
- North Kansas City Hospital
-
Kansas City, Missouri, Forenede Stater, 64132
- Research Medical Center
-
Kansas City, Missouri, Forenede Stater, 64111
- Saint Luke's Cancer Institute at Saint Luke's Hospital
-
Kansas City, Missouri, Forenede Stater, 64118
- Heartland Hematology Oncology Associates, Incorporated
-
Lee's Summit, Missouri, Forenede Stater, 64086
- Saint Luke's East - Lee's Summit
-
Saint Joseph, Missouri, Forenede Stater, 64507
- Saint Joseph Oncology, Incorporated
-
Saint Louis, Missouri, Forenede Stater, 63131
- Missouri Baptist Cancer Center
-
Saint Louis, Missouri, Forenede Stater, 63110
- Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
-
-
Nebraska
-
Grand Island, Nebraska, Forenede Stater, 68803
- Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center
-
North Platte, Nebraska, Forenede Stater, 69103
- Callahan Cancer Center at Great Plains Regional Medical Center
-
Omaha, Nebraska, Forenede Stater, 68198-6805
- UNMC Eppley Cancer Center at the University of Nebraska Medical Center
-
-
Nevada
-
Las Vegas, Nevada, Forenede Stater, 89109
- Sunrise Hospital and Medical Center
-
Las Vegas, Nevada, Forenede Stater, 89102
- University Medical Center of Southern Nevada
-
Las Vegas, Nevada, Forenede Stater, 89106
- CCOP - Nevada Cancer Research Foundation
-
-
New Hampshire
-
Concord, New Hampshire, Forenede Stater, 03301
- New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
-
Hooksett, New Hampshire, Forenede Stater, 03106
- New Hampshire Oncology - Hematology, PA - Hooksett
-
Laconia, New Hampshire, Forenede Stater, 03246
- Lakes Region General Hospital
-
Lebanon, New Hampshire, Forenede Stater, 03756-0002
- Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
-
Manchester, New Hampshire, Forenede Stater, 03102
- Norris Cotton Cancer Center at Catholic Medical Center
-
-
New Jersey
-
Voorhees, New Jersey, Forenede Stater, 08043
- Cancer Institute of New Jersey at Cooper - Voorhees
-
-
New York
-
Buffalo, New York, Forenede Stater, 14263-0001
- Roswell Park Cancer Institute
-
East Syracuse, New York, Forenede Stater, 13057
- CCOP - Hematology-Oncology Associates of Central New York
-
Glens Falls, New York, Forenede Stater, 12801
- Charles R. Wood Cancer Center at Glens Falls Hospital
-
Jamaica, New York, Forenede Stater, 11432
- Queens Cancer Center of Queens Hospital
-
Lake Success, New York, Forenede Stater, 11042
- Monter Cancer Center of the North Shore-LIJ Health System
-
Manhasset, New York, Forenede Stater, 11030
- CCOP - North Shore University Hospital
-
Manhasset, New York, Forenede Stater, 11030
- Don Monti Comprehensive Cancer Center at North Shore University Hospital
-
New Hyde Park, New York, Forenede Stater, 11040
- Long Island Jewish Medical Center
-
New York, New York, Forenede Stater, 10021
- New York Weill Cornell Cancer Center at Cornell University
-
New York, New York, Forenede Stater, 10029
- Mount Sinai Medical Center
-
Syracuse, New York, Forenede Stater, 13210
- Veterans Affairs Medical Center - Syracuse
-
Syracuse, New York, Forenede Stater, 13210
- SUNY Upstate Medical University Hospital
-
-
North Carolina
-
Asheville, North Carolina, Forenede Stater, 28801
- Mission Hospitals - Memorial Campus
-
Chapel Hill, North Carolina, Forenede Stater, 27599-7295
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
-
Charlotte, North Carolina, Forenede Stater, 28232-2861
- Blumenthal Cancer Center at Carolinas Medical Center
-
Charlotte, North Carolina, Forenede Stater, 28233-3549
- Presbyterian Cancer Center at Presbyterian Hospital
-
Concord, North Carolina, Forenede Stater, 28025
- Batte Cancer Center at Northeast Medical Center
-
Durham, North Carolina, Forenede Stater, 27710
- Duke Cancer Institute
-
Goldsboro, North Carolina, Forenede Stater, 27534
- Wayne Memorial Hospital, Incorporated
-
Greenville, North Carolina, Forenede Stater, 27834
- Leo W. Jenkins Cancer Center at ECU Medical School
-
Hendersonville, North Carolina, Forenede Stater, 28791
- Pardee Memorial Hospital
-
Kinston, North Carolina, Forenede Stater, 28501
- Kinston Medical Specialists
-
Shelby, North Carolina, Forenede Stater, 28150
- Cleveland Regional Medical Center
-
Statesville, North Carolina, Forenede Stater, 28677
- Iredell Memorial Hospital
-
Winston-Salem, North Carolina, Forenede Stater, 27157-1096
- Wake Forest University Comprehensive Cancer Center
-
Winston-Salem, North Carolina, Forenede Stater, 27103
- Forsyth Regional Cancer Center at Forsyth Medical Center
-
-
Ohio
-
Columbus, Ohio, Forenede Stater, 43210-1240
- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center
-
-
Oklahoma
-
Norman, Oklahoma, Forenede Stater, 73071
- Cancer Care Associates - Norman
-
Oklahoma City, Oklahoma, Forenede Stater, 73104
- Oklahoma University Cancer Institute
-
Oklahoma City, Oklahoma, Forenede Stater, 73120
- Cancer Care Associates - Mercy Campus
-
-
Pennsylvania
-
Pittsburgh, Pennsylvania, Forenede Stater, 15224-1791
- Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
-
-
Rhode Island
-
Providence, Rhode Island, Forenede Stater, 02906
- Miriam Hospital
-
Providence, Rhode Island, Forenede Stater, 02903
- Rhode Island Hospital Comprehensive Cancer Center
-
-
South Carolina
-
Florence, South Carolina, Forenede Stater, 29501
- McLeod Regional Medical Center
-
Greenville, South Carolina, Forenede Stater, 29615
- CCOP - Greenville
-
Greenville, South Carolina, Forenede Stater, 29605
- Greenville Hospital Cancer Center
-
Greenville, South Carolina, Forenede Stater, 29615
- Cancer Centers of the Carolinas - Eastside
-
Greenville, South Carolina, Forenede Stater, 29605
- Cancer Centers of the Carolinas - Faris Road
-
Greenville, South Carolina, Forenede Stater, 29605
- Cancer Centers of the Carolinas - Grove Commons
-
Greer, South Carolina, Forenede Stater, 29650
- Cancer Centers of the Carolinas - Greer Medical Oncology
-
Seneca, South Carolina, Forenede Stater, 29672
- Cancer Centers of the Carolinas - Seneca
-
Spartanburg, South Carolina, Forenede Stater, 29307
- Cancer Centers of the Carolinas - Spartanburg
-
-
Vermont
-
Berlin, Vermont, Forenede Stater, 05602
- Mountainview Medical
-
Burlington, Vermont, Forenede Stater, 05401
- Fletcher Allen Health Care - University Health Center Campus
-
-
Virginia
-
Danville, Virginia, Forenede Stater, 24541
- Danville Regional Medical Center
-
Martinsville, Virginia, Forenede Stater, 24115
- Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County
-
Richmond, Virginia, Forenede Stater, 23298-0037
- Virginia Commonwealth University Massey Cancer Center
-
-
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
- Voksen
- Ældre voksen
Tager imod sunde frivillige
Ingen
Prøveudtagningsmetode
Ikke-sandsynlighedsprøve
Studiebefolkning
Patienter diagnosticeret med leukæmi eller myelodysplasi.
Beskrivelse
- Tidligere ubehandlede patienter på en CALGB-behandlingsprotokol for leukæmi (akut eller kronisk) eller myelodysplasi er kvalificerede. Patienter skal registreres til CALGB 9665, før de modtager nogen form for behandling for deres sygdom.
- Underskrevet informeret samtykke
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Kohorter og interventioner
Gruppe / kohorte |
Intervention / Behandling |
|---|---|
|
Gruppe 1
Tidligere ubehandlede patienter på en CALGB-behandlingsprotokol for leukæmi (akut eller kronisk) eller myelodysplasi er kvalificerede.
Patienter skal registreres til CALGB 9665, før de modtager nogen form for behandling for deres sygdom.
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Tidsramme |
|---|---|
|
Indsamling og opbevaring af prøver fra nyligt diagnosticerede patienter med akut eller kronisk leukæmi eller myelodysplastiske syndromer tilmeldt en CALGB-protokol
Tidsramme: Ved diagnose
|
Ved diagnose
|
|
Indsamling og opbevaring af prøver fra nyligt diagnosticerede patienter med akut eller kronisk leukæmi eller myelodysplastiske syndromer tilmeldt en CALGB-protokol
Tidsramme: Ved tilbagefald
|
Ved tilbagefald
|
|
Indsamling og opbevaring af prøver fra nyligt diagnosticerede patienter med akut eller kronisk leukæmi eller myelodysplastiske syndromer tilmeldt en CALGB-protokol
Tidsramme: Ved remission
|
Ved remission
|
Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Samarbejdspartnere
Efterforskere
- Studiestol: Michael Caligiuri, MD, Ohio State University Comprehensive Cancer Center
Publikationer og nyttige links
Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.
Generelle publikationer
- Walker CJ, Kohlschmidt J, Eisfeld AK, Mrozek K, Liyanarachchi S, Song C, Nicolet D, Blachly JS, Bill M, Papaioannou D, Oakes CC, Giacopelli B, Genutis LK, Maharry SE, Orwick S, Archer KJ, Powell BL, Kolitz JE, Uy GL, Wang ES, Carroll AJ, Stone RM, Byrd JC, de la Chapelle A, Bloomfield CD. Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia. Clin Cancer Res. 2019 Nov 1;25(21):6524-6531. doi: 10.1158/1078-0432.CCR-19-0725. Epub 2019 Aug 2.
- Liu TH, Raval A, Chen SS, Matkovic JJ, Byrd JC, Plass C. CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia. Cancer Res. 2006 Jan 15;66(2):653-8. doi: 10.1158/0008-5472.CAN-05-3712.
- Fobare S, Kohlschmidt J, Ozer HG, Mrozek K, Nicolet D, Mims AS, Garzon R, Blachly JS, Orwick S, Carroll AJ, Stone RM, Wang ES, Kolitz JE, Powell BL, Oakes CC, Eisfeld AK, Hertlein E, Byrd JC. Molecular, clinical, and prognostic implications of PTPN11 mutations in acute myeloid leukemia. Blood Adv. 2022 Mar 8;6(5):1371-1380. doi: 10.1182/bloodadvances.2021006242.
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Faktiske)
1. maj 1996
Primær færdiggørelse (Anslået)
1. december 2024
Datoer for studieregistrering
Først indsendt
9. maj 2009
Først indsendt, der opfyldte QC-kriterier
9. maj 2009
Først opslået (Anslået)
12. maj 2009
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
31. juli 2024
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
30. juli 2024
Sidst verificeret
1. juli 2024
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- CALGB-9665
- U10CA031946 (U.S. NIH-bevilling/kontrakt)
- CDR0000271412 (Registry Identifier: NCI Physician Data Query)
Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .