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Afprøvning af timingen af Pembrolizumab alene eller med kemoterapi som førstelinjebehandling og vedligeholdelse ved ikke-småcellet lungekræft

23. april 2024 opdateret af: National Cancer Institute (NCI)

EA5163/S1709 INSIGNA: Et randomiseret, fase III-studie af førstelinjeimmunterapi alene eller i kombination med kemoterapi i induktion/vedligeholdelse eller efterprogression ved avanceret ikke-småcellet ikke-småcellet lungekræft (NSCLC) med immunbiomarkør SIGNature-drevet analyse

Dette fase III-forsøg undersøger, om pembrolizumab alene som førstelinjebehandling efterfulgt af pemetrexed og carboplatin med eller uden pembrolizumab efter sygdomsprogression er bedre end induktion med pembrolizumab, pemetrexed og carboplatin efterfulgt af pembrolizumab og pemetrexed vedligeholdelse til behandling af patienter med trin IV non -pladeeplade ikke-småcellet lungekræft. Immunterapi med monoklonale antistoffer, såsom pembrolizumab, kan hjælpe kroppens immunsystem med at angribe kræften og kan forstyrre tumorcellernes evne til at vokse og sprede sig. Lægemidler, der bruges i kemoterapi, såsom pemetrexed og carboplatin, virker på forskellige måder for at stoppe væksten af tumorceller, enten ved at dræbe cellerne, ved at stoppe dem i at dele sig eller ved at stoppe dem i at sprede sig. Det vides endnu ikke, om indgivelse af første-line pembrolizumab efterfulgt af pemetrexed og carboplatin med eller uden pembrolizumab virker bedre til behandling af patienter med ikke-pladecellet ikke-småcellet cancer.

Studieoversigt

Status

Aktiv, ikke rekrutterende

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

PRIMÆR MÅL:

I. At evaluere den samlede overlevelse (OS) i hver af de 2 eksperimentelle arme (arm A og B) til kontrol (arm C).

SEKUNDÆRE MÅL:

I. At evaluere progressionsfri overlevelse (PFS) pr. responsevalueringskriterier i solide tumorer (RECIST) 1.1 for arm C versus hver af arm A og B.

II. At evaluere de bedste objektive svarrater pr. RECIST 1.1 for arm C versus hver af arm A og B.

III. At estimere toksicitet inden for hver af behandlingsarmene via CTCAE-kriterierne (Common Terminology Criteria for Adverse Events).

IV. At sammenligne resultater mellem arm A og B. V. At sammenligne resultater efter behandlingsarm inden for undergrupper defineret af et cutpoint for PD-L1-ekspression på >= 50 %.

BIOMARKØRMÅL:

I. At indsamle og banke væv og blod til fremtidige forskningsstudier, herunder potentiel udvikling af en prognostisk og prædiktiv signatur for MK-3475 (pembrolizumab) i kombination med kemoterapi versus MK-3475 (pembrolizumab) alene.

UNDERSØGENDE BILLEDMÅL:

I. At indsamle og banke standard-of-care computertomografi (CT) billeddannelse ved baseline og de første tre opfølgende scanninger efter behandling for at udvikle den radiomiske risikoscore med følgende eksplorative mål:

Ia. Valider den radiomiske risiko-score på scanninger før behandling samt beregne forskelle mellem scanninger før og efter behandling (deltafunktioner) for at bestemme, hvilke patienter der vil drage fordel af førstelinjespembrolizumab i metastaserende omgivelser i både lav (< 50 %) og høje (> 50 %) PD-L1-kohorter, der bruger patienter i arm 1 og arm 2 af forsøget, hvor pembrolizumab anvendes som førstelinjebehandling.

Ib. At bruge Radiomic Risk-scoren til at forudsige, hvilke patienter der ville have gavn af kombinationen pembrolizumab og efterfølgende kemoterapi vs. immunterapi alene i både lav (< 50 %) og høj (> 50 %) PD-L1-kohorter med patienter, der fortsatte med at modtage kemoterapi som anden linje og stratificering af patienterne baseret på dem, der fik gavn af pembrolizumab plus kemoterapi versus (vs.) pembrolizumab alene.

Ic. Eksplorativ analyse for andre radiomiske profiler til at forudsige respons.

OVERSIGT: Patienterne randomiseres til 1 ud af 3 arme.

ARM A: Patienterne får pembrolizumab intravenøst (IV) over 30 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år i fravær af sygdomsprogression eller uacceptabel toksicitet. Inden for 6 uger efter sygdomsprogression får patienterne pemetrexed IV over 10 minutter og carboplatin IV over 30 minutter på dag 1. Behandlingen gentages hver 21. dag i op til 4 cyklusser i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienter kan derefter få pemetrexed IV over 10 minutter på dag 1. Cykler gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM B: Patienterne får pembrolizumab IV over 30 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år i fravær af sygdomsprogression eller uacceptabel toksicitet. Inden for 6 uger efter sygdomsprogression får patienterne pembrolizumab IV over 30 minutter, pemetrexed IV over 10 minutter og carboplatin IV over 30 minutter på dag 1. Behandlingen gentages hver 21. dag i op til 4 cyklusser i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienterne får derefter pembrolizumab IV over 30 minutter og pemetrexed IV over 10 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år for pembrolizumab i fravær af sygdomsprogression eller uacceptabel toksicitet og indtil sygdomsprogression for pemetrexed.

ARM C: Patienterne får pembrolizumab IV over 30 minutter, pemetrexed IV over 10 minutter og carboplatin IV over 30 minutter på dag 1. Behandlingen gentages hver 21. dag i op til 4 cyklusser i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienterne får derefter pembrolizumab IV over 30 minutter og pemetrexed IV over 10 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år for pembrolizumab i fravær af sygdomsprogression eller uacceptabel toksicitet og indtil sygdomsprogression for pemetrexed.

Efter afsluttet studiebehandling følges patienterne op i 5 år.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

600

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Canada
- Alberta
  - Calgary, Alberta, Canada, T2N 4N2
    - Tom Baker Cancer Centre
  - Edmonton, Alberta, Canada, T6G 1Z2
    - Cross Cancer Institute
- British Columbia
  - Surrey, British Columbia, Canada, V3V 1Z2
    - BCCA-Fraser Valley Cancer Centre
  - Vancouver, British Columbia, Canada, V5Z 4E6
    - BCCA-Vancouver Cancer Centre
- New Brunswick
  - Saint John, New Brunswick, Canada, E2L 4L2
    - Atlantic Health Sciences Corporation-Saint John Regional Hospital
- Ontario
  - Kingston, Ontario, Canada, K7L 2V7
    - Kingston Health Sciences Centre
  - Saint Catharines, Ontario, Canada, L2S 0A9
    - Niagara Health System-Saint Catharines General
  - Thunder Bay, Ontario, Canada, P7B 6V4
    - Thunder Bay Regional Health Science Centre
  - Toronto, Ontario, Canada, M5G 2M9
    - University Health Network-Princess Margaret Hospital
- Prince Edward Island
  - Charlottetown, Prince Edward Island, Canada, C1A 8T5
    - PEI Cancer Treatment Centre-Queen Elizabeth Hospital
- Quebec
  - Montreal, Quebec, Canada, H3H 2R9
    - The Research Institute of the McGill University Health Centre (MUHC)
  - Quebec City, Quebec, Canada, G1J 1Z4
    - CHA Hopital L'Enfant-Jesus
Forenede Stater
- Alabama
  - Mobile, Alabama, Forenede Stater, 36688
    - University of South Alabama Mitchell Cancer Institute
- Alaska
  - Anchorage, Alaska, Forenede Stater, 98508
    - Anchorage Associates in Radiation Medicine
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Breast Care and Surgery LLC
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Oncology and Hematology LLC
  - Anchorage, Alaska, Forenede Stater, 99508
    - Alaska Women's Cancer Care
  - Anchorage, Alaska, Forenede Stater, 99508
    - Anchorage Oncology Centre
  - Anchorage, Alaska, Forenede Stater, 99508
    - Katmai Oncology Group
  - Anchorage, Alaska, Forenede Stater, 99508
    - Providence Alaska Medical Center
  - Anchorage, Alaska, Forenede Stater, 99504
    - Anchorage Radiation Therapy Center
  - Fairbanks, Alaska, Forenede Stater, 99701
    - Fairbanks Memorial Hospital
- Arizona
  - Kingman, Arizona, Forenede Stater, 86401
    - Kingman Regional Medical Center
  - Phoenix, Arizona, Forenede Stater, 85004
    - Cancer Center at Saint Joseph's
  - Tucson, Arizona, Forenede Stater, 85704
    - University of Arizona Cancer Center-Orange Grove Campus
  - Tucson, Arizona, Forenede Stater, 85719
    - Banner University Medical Center - Tucson
  - Tucson, Arizona, Forenede Stater, 85719
    - University of Arizona Cancer Center-North Campus
- Arkansas
  - Fort Smith, Arkansas, Forenede Stater, 72903
    - Mercy Hospital Fort Smith
  - Hot Springs, Arkansas, Forenede Stater, 71913
    - CHI Saint Vincent Cancer Center Hot Springs
  - Jonesboro, Arkansas, Forenede Stater, 72401
    - NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
  - Little Rock, Arkansas, Forenede Stater, 72205
    - CARTI Cancer Center
- California
  - Anaheim, California, Forenede Stater, 92806
    - Kaiser Permanente-Anaheim
  - Antioch, California, Forenede Stater, 94531
    - Kaiser Permanente-Deer Valley Medical Center
  - Arroyo Grande, California, Forenede Stater, 93420
    - PCR Oncology
  - Arroyo Grande, California, Forenede Stater, 93420
    - Mission Hope Medical Oncology - Arroyo Grande
  - Auburn, California, Forenede Stater, 95602
    - Sutter Auburn Faith Hospital
  - Auburn, California, Forenede Stater, 95603
    - Sutter Cancer Centers Radiation Oncology Services-Auburn
  - Baldwin Park, California, Forenede Stater, 91706
    - Kaiser Permanente-Baldwin Park
  - Bellflower, California, Forenede Stater, 90706
    - Kaiser Permanente-Bellflower
  - Berkeley, California, Forenede Stater, 94704
    - Alta Bates Summit Medical Center-Herrick Campus
  - Beverly Hills, California, Forenede Stater, 90211
    - Tower Cancer Research Foundation
  - Burbank, California, Forenede Stater, 91505
    - Providence Saint Joseph Medical Center/Disney Family Cancer Center
  - Burlingame, California, Forenede Stater, 94010
    - Mills-Peninsula Medical Center
  - Cameron Park, California, Forenede Stater, 95682
    - Sutter Cancer Centers Radiation Oncology Services-Cameron Park
  - Carmichael, California, Forenede Stater, 95608
    - Mercy San Juan Medical Center
  - Carmichael, California, Forenede Stater, 95608
    - Mercy Cancer Center - Carmichael
  - Castro Valley, California, Forenede Stater, 94546
    - Eden Hospital Medical Center
  - Davis, California, Forenede Stater, 95616
    - Sutter Davis Hospital
  - Dublin, California, Forenede Stater, 94568
    - Kaiser Permanente Dublin
  - El Segundo, California, Forenede Stater, 90245
    - 21st Century Oncology - El Segundo
  - Elk Grove, California, Forenede Stater, 95758
    - Mercy Cancer Center - Elk Grove
  - Fontana, California, Forenede Stater, 92335
    - Kaiser Permanente-Fontana
  - Fremont, California, Forenede Stater, 94538
    - Kaiser Permanente-Fremont
  - Fremont, California, Forenede Stater, 94538
    - Palo Alto Medical Foundation-Fremont
  - Fresno, California, Forenede Stater, 93720
    - Kaiser Permanente-Fresno
  - Fresno, California, Forenede Stater, 93720
    - Fresno Cancer Center
  - Harbor City, California, Forenede Stater, 90710
    - Kaiser Permanente - Harbor City
  - Irvine, California, Forenede Stater, 92618
    - Kaiser Permanente-Irvine
  - La Jolla, California, Forenede Stater, 92093
    - UC San Diego Moores Cancer Center
  - Los Angeles, California, Forenede Stater, 90027
    - Kaiser Permanente Los Angeles Medical Center
  - Los Angeles, California, Forenede Stater, 90048
    - Cedars Sinai Medical Center
  - Los Angeles, California, Forenede Stater, 90034
    - Kaiser Permanente West Los Angeles
  - Marysville, California, Forenede Stater, 95901
    - Fremont - Rideout Cancer Center
  - Merced, California, Forenede Stater, 95340
    - Mercy UC Davis Cancer Center
  - Modesto, California, Forenede Stater, 95355
    - Memorial Medical Center
  - Modesto, California, Forenede Stater, 95356
    - Kaiser Permanente-Modesto
  - Mountain View, California, Forenede Stater, 94040
    - Palo Alto Medical Foundation-Camino Division
  - Mountain View, California, Forenede Stater, 94040
    - Palo Alto Medical Foundation-Gynecologic Oncology
  - Novato, California, Forenede Stater, 94945
    - Sutter Cancer Research Consortium
  - Oakland, California, Forenede Stater, 94611
    - Kaiser Permanente-Oakland
  - Oakland, California, Forenede Stater, 94611
    - Kaiser Permanente Oakland-Broadway
  - Ontario, California, Forenede Stater, 91761
    - Kaiser Permanente-Ontario
  - Orange, California, Forenede Stater, 92868
    - Saint Joseph Hospital - Orange
  - Palo Alto, California, Forenede Stater, 94304
    - VA Palo Alto Health Care System
  - Palo Alto, California, Forenede Stater, 94301
    - Palo Alto Medical Foundation Health Care
  - Panorama City, California, Forenede Stater, 91402
    - Kaiser Permanente - Panorama City
  - Rancho Cordova, California, Forenede Stater, 95670
    - Kaiser Permanente-Rancho Cordova Cancer Center
  - Redwood City, California, Forenede Stater, 94063
    - Kaiser Permanente-Redwood City
  - Redwood City, California, Forenede Stater, 94063
    - Kaiser Permanente- Marshall Medical Offices
  - Richmond, California, Forenede Stater, 94801
    - Kaiser Permanente-Richmond
  - Riverside, California, Forenede Stater, 92505
    - Kaiser Permanente-Riverside
  - Rocklin, California, Forenede Stater, 95765
    - Mercy Cancer Center - Rocklin
  - Rohnert Park, California, Forenede Stater, 94928
    - Rohnert Park Cancer Center
  - Roseville, California, Forenede Stater, 95678
    - The Permanente Medical Group-Roseville Radiation Oncology
  - Roseville, California, Forenede Stater, 95661
    - Kaiser Permanente-Roseville
  - Roseville, California, Forenede Stater, 95661
    - Sutter Cancer Centers Radiation Oncology Services-Roseville
  - Roseville, California, Forenede Stater, 95661
    - Sutter Roseville Medical Center
  - Sacramento, California, Forenede Stater, 95816
    - Sutter Medical Center Sacramento
  - Sacramento, California, Forenede Stater, 95817
    - University of California Davis Comprehensive Cancer Center
  - Sacramento, California, Forenede Stater, 95814
    - Kaiser Permanente Downtown Commons
  - Sacramento, California, Forenede Stater, 95823
    - Kaiser Permanente-South Sacramento
  - Sacramento, California, Forenede Stater, 95823
    - South Sacramento Cancer Center
  - Sacramento, California, Forenede Stater, 95816
    - Mercy Cancer Center - Sacramento
  - Saint Helena, California, Forenede Stater, 94574
    - Saint Helena Hospital
  - San Diego, California, Forenede Stater, 92120
    - Kaiser Permanente-San Diego Zion
  - San Diego, California, Forenede Stater, 92108
    - Kaiser Permanente-San Diego Mission
  - San Diego, California, Forenede Stater, 92103
    - UC San Diego Medical Center - Hillcrest
  - San Francisco, California, Forenede Stater, 94115
    - Kaiser Permanente-San Francisco
  - San Francisco, California, Forenede Stater, 94115
    - California Pacific Medical Center-Pacific Campus
  - San Francisco, California, Forenede Stater, 94110
    - Zuckerberg San Francisco General Hospital
  - San Jose, California, Forenede Stater, 95119
    - Kaiser Permanente-Santa Teresa-San Jose
  - San Leandro, California, Forenede Stater, 94577
    - Kaiser Permanente San Leandro
  - San Luis Obispo, California, Forenede Stater, 93401
    - Pacific Central Coast Health Center-San Luis Obispo
  - San Marcos, California, Forenede Stater, 92078
    - Kaiser Permanente-San Marcos
  - San Rafael, California, Forenede Stater, 94903
    - Kaiser San Rafael-Gallinas
  - Santa Clara, California, Forenede Stater, 95051
    - Kaiser Permanente Medical Center - Santa Clara
  - Santa Cruz, California, Forenede Stater, 95065
    - Palo Alto Medical Foundation-Santa Cruz
  - Santa Maria, California, Forenede Stater, 93444
    - Mission Hope Medical Oncology - Santa Maria
  - Santa Rosa, California, Forenede Stater, 95403
    - Kaiser Permanente-Santa Rosa
  - Santa Rosa, California, Forenede Stater, 95403
    - Sutter Pacific Medical Foundation
  - South San Francisco, California, Forenede Stater, 94080
    - Kaiser Permanente Cancer Treatment Center
  - South San Francisco, California, Forenede Stater, 94080
    - Kaiser Permanente-South San Francisco
  - Stockton, California, Forenede Stater, 95210
    - Kaiser Permanente-Stockton
  - Sunnyvale, California, Forenede Stater, 94086
    - Palo Alto Medical Foundation-Sunnyvale
  - Tarzana, California, Forenede Stater, 91356
    - Cedars-Sinai Cancer - Tarzana
  - Torrance, California, Forenede Stater, 90509
    - Torrance Memorial Medical Center
  - Torrance, California, Forenede Stater, 90505
    - Torrance Memorial Physician Network - Cancer Care
  - Vacaville, California, Forenede Stater, 95688
    - Kaiser Permanente Medical Center-Vacaville
  - Vacaville, California, Forenede Stater, 95687
    - Sutter Cancer Centers Radiation Oncology Services-Vacaville
  - Vallejo, California, Forenede Stater, 94589
    - Kaiser Permanente-Vallejo
  - Vallejo, California, Forenede Stater, 94589
    - Sutter Solano Medical Center/Cancer Center
  - Walnut Creek, California, Forenede Stater, 94596
    - Kaiser Permanente-Walnut Creek
  - Woodland, California, Forenede Stater, 95695
    - Woodland Memorial Hospital
  - Woodland Hills, California, Forenede Stater, 91367
    - Kaiser Permanente-Woodland Hills
- Colorado
  - Aurora, Colorado, Forenede Stater, 80012
    - Rocky Mountain Cancer Centers-Aurora
  - Aurora, Colorado, Forenede Stater, 80012
    - The Medical Center of Aurora
  - Aurora, Colorado, Forenede Stater, 80045
    - UCHealth University of Colorado Hospital
  - Boulder, Colorado, Forenede Stater, 80301
    - Boulder Community Hospital
  - Boulder, Colorado, Forenede Stater, 80303
    - Boulder Community Foothills Hospital
  - Boulder, Colorado, Forenede Stater, 80304
    - Rocky Mountain Cancer Centers-Boulder
  - Centennial, Colorado, Forenede Stater, 80112
    - Rocky Mountain Cancer Centers - Centennial
  - Colorado Springs, Colorado, Forenede Stater, 80907
    - Penrose-Saint Francis Healthcare
  - Colorado Springs, Colorado, Forenede Stater, 80907
    - Rocky Mountain Cancer Centers-Penrose
  - Colorado Springs, Colorado, Forenede Stater, 80923
    - Saint Francis Cancer Center
  - Denver, Colorado, Forenede Stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forenede Stater, 80205
    - Kaiser Permanente-Franklin
  - Denver, Colorado, Forenede Stater, 80218
    - Presbyterian - Saint Lukes Medical Center - Health One
  - Denver, Colorado, Forenede Stater, 80218
    - SCL Health Saint Joseph Hospital
  - Denver, Colorado, Forenede Stater, 80220
    - Rose Medical Center
  - Denver, Colorado, Forenede Stater, 80218
    - Rocky Mountain Cancer Centers-Midtown
  - Denver, Colorado, Forenede Stater, 80220
    - Rocky Mountain Cancer Centers-Rose
  - Denver, Colorado, Forenede Stater, 80218
    - Colorado Blood Cancer Institute
  - Denver, Colorado, Forenede Stater, 80204
    - Cancer Center of Colorado at Sloan's Lake
  - Denver, Colorado, Forenede Stater, 80209
    - The Women's Imaging Center
  - Denver, Colorado, Forenede Stater, 80206
    - National Jewish Health-Main Campus
  - Denver, Colorado, Forenede Stater, 80220
    - Western Surgical Care
  - Durango, Colorado, Forenede Stater, 81301
    - Mercy Medical Center
  - Durango, Colorado, Forenede Stater, 81301
    - Southwest Oncology PC
  - Englewood, Colorado, Forenede Stater, 80113
    - Mountain Blue Cancer Care Center - Swedish
  - Englewood, Colorado, Forenede Stater, 80113
    - Swedish Medical Center
  - Englewood, Colorado, Forenede Stater, 80113
    - Rocky Mountain Cancer Centers - Swedish
  - Englewood, Colorado, Forenede Stater, 80113
    - The Melanoma and Skin Cancer Institute
  - Fort Collins, Colorado, Forenede Stater, 80524
    - Poudre Valley Hospital
  - Fort Collins, Colorado, Forenede Stater, 80528
    - Cancer Care and Hematology-Fort Collins
  - Golden, Colorado, Forenede Stater, 80401
    - Mountain Blue Cancer Care Center
  - Golden, Colorado, Forenede Stater, 80401
    - National Jewish Health-Western Hematology Oncology
  - Grand Junction, Colorado, Forenede Stater, 81501
    - Saint Mary's Hospital and Regional Medical Center
  - Grand Junction, Colorado, Forenede Stater, 81505
    - Grand Valley Oncology
  - Greeley, Colorado, Forenede Stater, 80631
    - North Colorado Medical Center
  - Greeley, Colorado, Forenede Stater, 80631
    - UCHealth Greeley Hospital
  - Highlands Ranch, Colorado, Forenede Stater, 80129
    - UCHealth Highlands Ranch Hospital
  - Lafayette, Colorado, Forenede Stater, 80026
    - Good Samaritan Medical Center
  - Lafayette, Colorado, Forenede Stater, 80026
    - Kaiser Permanente-Rock Creek
  - Lakewood, Colorado, Forenede Stater, 80228
    - Saint Anthony Hospital
  - Lakewood, Colorado, Forenede Stater, 80228
    - Rocky Mountain Cancer Centers-Lakewood
  - Littleton, Colorado, Forenede Stater, 80120
    - Rocky Mountain Cancer Centers-Littleton
  - Littleton, Colorado, Forenede Stater, 80122
    - Littleton Adventist Hospital
  - Lone Tree, Colorado, Forenede Stater, 80124
    - Kaiser Permanente-Lone Tree
  - Lone Tree, Colorado, Forenede Stater, 80124
    - Sky Ridge Medical Center
  - Lone Tree, Colorado, Forenede Stater, 80124
    - Rocky Mountain Cancer Centers-Sky Ridge
  - Longmont, Colorado, Forenede Stater, 80501
    - Longmont United Hospital
  - Longmont, Colorado, Forenede Stater, 80501
    - Rocky Mountain Cancer Centers-Longmont
  - Loveland, Colorado, Forenede Stater, 80539
    - McKee Medical Center
  - Loveland, Colorado, Forenede Stater, 80538
    - Medical Center of the Rockies
  - Parker, Colorado, Forenede Stater, 80138
    - Parker Adventist Hospital
  - Parker, Colorado, Forenede Stater, 80138
    - Rocky Mountain Cancer Centers-Parker
  - Pueblo, Colorado, Forenede Stater, 81004
    - Saint Mary Corwin Medical Center
  - Pueblo, Colorado, Forenede Stater, 81008
    - Rocky Mountain Cancer Centers - Pueblo
  - Thornton, Colorado, Forenede Stater, 80260
    - Rocky Mountain Cancer Centers-Thornton
  - Thornton, Colorado, Forenede Stater, 80260
    - National Jewish Health-Northern Hematology Oncology
  - Wheat Ridge, Colorado, Forenede Stater, 80033
    - SCL Health Lutheran Medical Center
- Connecticut
  - Derby, Connecticut, Forenede Stater, 06418
    - Smilow Cancer Hospital-Derby Care Center
  - Fairfield, Connecticut, Forenede Stater, 06824
    - Smilow Cancer Hospital Care Center-Fairfield
  - Guilford, Connecticut, Forenede Stater, 06437
    - Smilow Cancer Hospital Care Center - Guilford
  - Hartford, Connecticut, Forenede Stater, 06105
    - Smilow Cancer Hospital Care Center at Saint Francis
  - New Haven, Connecticut, Forenede Stater, 06520
    - Yale University
  - New Haven, Connecticut, Forenede Stater, 06510
    - Smilow Cancer Center/Yale-New Haven Hospital
  - North Haven, Connecticut, Forenede Stater, 06473
    - Yale-New Haven Hospital North Haven Medical Center
  - Orange, Connecticut, Forenede Stater, 06477
    - Smilow Cancer Hospital-Orange Care Center
  - Stamford, Connecticut, Forenede Stater, 06904
    - Stamford Hospital/Bennett Cancer Center
  - Stamford, Connecticut, Forenede Stater, 06902
    - Smilow Cancer Hospital Care Center at Long Ridge
  - Torrington, Connecticut, Forenede Stater, 06790
    - Smilow Cancer Hospital-Torrington Care Center
  - Trumbull, Connecticut, Forenede Stater, 06611
    - Smilow Cancer Hospital Care Center-Trumbull
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Smilow Cancer Hospital-Waterbury Care Center
  - Waterford, Connecticut, Forenede Stater, 06385
    - Smilow Cancer Hospital Care Center - Waterford
  - West Haven, Connecticut, Forenede Stater, 06516
    - Veterans Affairs Connecticut Healthcare System-West Haven Campus
- Delaware
  - Frankford, Delaware, Forenede Stater, 19945
    - Beebe South Coastal Health Campus
  - Lewes, Delaware, Forenede Stater, 19958
    - Beebe Medical Center
  - Newark, Delaware, Forenede Stater, 19713
    - Helen F Graham Cancer Center
  - Newark, Delaware, Forenede Stater, 19713
    - Delaware Clinical and Laboratory Physicians PA
  - Newark, Delaware, Forenede Stater, 19713
    - Medical Oncology Hematology Consultants PA
  - Newark, Delaware, Forenede Stater, 19718
    - Christiana Care Health System-Christiana Hospital
  - Rehoboth Beach, Delaware, Forenede Stater, 19971
    - Beebe Health Campus
  - Seaford, Delaware, Forenede Stater, 19973
    - TidalHealth Nanticoke / Allen Cancer Center
  - Wilmington, Delaware, Forenede Stater, 19801
    - Christiana Care Health System-Wilmington Hospital
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20010
    - MedStar Washington Hospital Center
  - Washington, District of Columbia, Forenede Stater, 20007
    - Medstar Georgetown University Hospital
  - Washington, District of Columbia, Forenede Stater, 20016
    - Sibley Memorial Hospital
  - Washington, District of Columbia, Forenede Stater, 20037
    - George Washington University Medical Center
- Florida
  - Aventura, Florida, Forenede Stater, 33180
    - Mount Sinai Comprehensive Cancer Center at Aventura
  - Aventura, Florida, Forenede Stater, 33180
    - GenesisCare USA - Aventura FP
  - Aventura, Florida, Forenede Stater, 33180
    - GenesisCare USA - Aventura
  - Boca Raton, Florida, Forenede Stater, 33428
    - GenesisCare USA - Boca Raton FP02
  - Boca Raton, Florida, Forenede Stater, 33431
    - GenesisCare USA - Boca Ration FP06
  - Fort Lauderdale, Florida, Forenede Stater, 33308
    - Holy Cross Hospital
  - Fort Myers, Florida, Forenede Stater, 33908
    - GenesisCare USA - Gladiolus
  - Gainesville, Florida, Forenede Stater, 32610
    - University of Florida Health Science Center - Gainesville
  - Jacksonville, Florida, Forenede Stater, 32224-9980
    - Mayo Clinic in Florida
  - Key West, Florida, Forenede Stater, 33040
    - GenesisCare USA - Key West
  - Lakewood Ranch, Florida, Forenede Stater, 34202
    - GenesisCare USA - Lakewood Ranch
  - Miami Beach, Florida, Forenede Stater, 33140
    - Mount Sinai Medical Center
  - Palm Beach Gardens, Florida, Forenede Stater, 33410
    - GenesisCare USA - Palm Beach Gardens
  - Pensacola, Florida, Forenede Stater, 32504
    - Sacred Heart Hospital
  - Plantation, Florida, Forenede Stater, 33324
    - GenesisCare USA - Plantation
  - Tampa, Florida, Forenede Stater, 33612
    - Moffitt Cancer Center
  - Tampa, Florida, Forenede Stater, 33607
    - Moffitt Cancer Center-International Plaza
  - Tampa, Florida, Forenede Stater, 33612
    - Moffitt Cancer Center - McKinley Campus
  - West Palm Beach, Florida, Forenede Stater, 33401
    - Good Samaritan Medical Center
  - Weston, Florida, Forenede Stater, 33331
    - Cleveland Clinic-Weston
- Georgia
  - Athens, Georgia, Forenede Stater, 30607
    - University Cancer and Blood Center LLC
  - Atlanta, Georgia, Forenede Stater, 30308
    - Emory University Hospital Midtown
  - Atlanta, Georgia, Forenede Stater, 30322
    - Emory University Hospital/Winship Cancer Institute
  - Atlanta, Georgia, Forenede Stater, 30342
    - Emory Saint Joseph's Hospital
  - Atlanta, Georgia, Forenede Stater, 30342
    - Northside Hospital
  - Augusta, Georgia, Forenede Stater, 30912
    - Augusta University Medical Center
  - Augusta, Georgia, Forenede Stater, 30901
    - Augusta Oncology Associates PC-D'Antignac
  - Augusta, Georgia, Forenede Stater, 30909
    - Augusta Oncology Associates PC-Wheeler
  - Braselton, Georgia, Forenede Stater, 30517
    - Northeast Georgia Medical Center Braselton
  - Decatur, Georgia, Forenede Stater, 30033
    - Atlanta VA Medical Center
  - Duluth, Georgia, Forenede Stater, 30096
    - Northside Hospital - Duluth
  - Gainesville, Georgia, Forenede Stater, 30501
    - Northeast Georgia Medical Center-Gainesville
  - Gainesville, Georgia, Forenede Stater, 30501
    - The Longstreet Clinic - Gainesville
  - Lawrenceville, Georgia, Forenede Stater, 30046
    - Northside Hospital - Gwinnett
  - Savannah, Georgia, Forenede Stater, 31405
    - Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
  - Savannah, Georgia, Forenede Stater, 31405
    - Summit Cancer Care-Candler
  - Snellville, Georgia, Forenede Stater, 30078
    - Suburban Hematology Oncology Associates - Snellville
  - Thomasville, Georgia, Forenede Stater, 31792
    - Lewis Hall Singletary Oncology Center
  - Valdosta, Georgia, Forenede Stater, 31602
    - South Georgia Medical Center/Pearlman Cancer Center
- Hawaii
  - 'Aiea, Hawaii, Forenede Stater, 96701
    - Pali Momi Medical Center
  - 'Aiea, Hawaii, Forenede Stater, 96701
    - Queen's Cancer Center - Pearlridge
  - 'Aiea, Hawaii, Forenede Stater, 96701
    - The Cancer Center of Hawaii-Pali Momi
  - 'Aiea, Hawaii, Forenede Stater, 96701
    - Straub Pearlridge Clinic
  - 'Aiea, Hawaii, Forenede Stater, 96701
    - Hawaii Cancer Care - Westridge
  - 'Ewa Beach, Hawaii, Forenede Stater, 96706
    - The Queen's Medical Center - West Oahu
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Queen's Medical Center
  - Honolulu, Hawaii, Forenede Stater, 96817
    - The Cancer Center of Hawaii-Liliha
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Hawaii Cancer Care Inc - Waterfront Plaza
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Queen's Cancer Cenrer - POB I
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Straub Clinic and Hospital
  - Honolulu, Hawaii, Forenede Stater, 96813
    - University of Hawaii Cancer Center
  - Honolulu, Hawaii, Forenede Stater, 96817
    - Hawaii Cancer Care Inc-Liliha
  - Honolulu, Hawaii, Forenede Stater, 96817
    - Kuakini Medical Center
  - Honolulu, Hawaii, Forenede Stater, 96817
    - Queen's Cancer Center - Kuakini
  - Honolulu, Hawaii, Forenede Stater, 96826
    - Kapiolani Medical Center for Women and Children
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Island Urology
  - Honolulu, Hawaii, Forenede Stater, 96819
    - Kaiser Permanente Moanalua Medical Center
  - Honolulu, Hawaii, Forenede Stater, 96817
    - Hawaii Diagnostic Radiology Services LLC
  - Kahului, Hawaii, Forenede Stater, 96732
    - Straub Medical Center - Kahului Clinic
  - Kailua, Hawaii, Forenede Stater, 96734
    - Castle Medical Center
  - Lihue, Hawaii, Forenede Stater, 96766
    - Wilcox Memorial Hospital and Kauai Medical Clinic
- Idaho
  - Boise, Idaho, Forenede Stater, 83706
    - Saint Alphonsus Cancer Care Center-Boise
  - Boise, Idaho, Forenede Stater, 83712
    - Saint Luke's Cancer Institute - Boise
  - Caldwell, Idaho, Forenede Stater, 83605
    - Saint Alphonsus Cancer Care Center-Caldwell
  - Coeur d'Alene, Idaho, Forenede Stater, 83814
    - Kootenai Health - Coeur d'Alene
  - Emmett, Idaho, Forenede Stater, 83617
    - Walter Knox Memorial Hospital
  - Fruitland, Idaho, Forenede Stater, 83619
    - Saint Luke's Cancer Institute - Fruitland
  - Meridian, Idaho, Forenede Stater, 83642
    - Idaho Urologic Institute-Meridian
  - Meridian, Idaho, Forenede Stater, 83642
    - Saint Luke's Cancer Institute - Meridian
  - Nampa, Idaho, Forenede Stater, 83686
    - Saint Luke's Cancer Institute - Nampa
  - Nampa, Idaho, Forenede Stater, 83687
    - Saint Alphonsus Cancer Care Center-Nampa
  - Post Falls, Idaho, Forenede Stater, 83854
    - Kootenai Clinic Cancer Services - Post Falls
  - Sandpoint, Idaho, Forenede Stater, 83864
    - Kootenai Cancer Clinic
  - Twin Falls, Idaho, Forenede Stater, 83301
    - Saint Luke's Cancer Institute - Twin Falls
- Illinois
  - Alton, Illinois, Forenede Stater, 62002
    - Saint Anthony's Health
  - Aurora, Illinois, Forenede Stater, 60504
    - Rush - Copley Medical Center
  - Barrington, Illinois, Forenede Stater, 60010
    - Advocate Good Shepherd Hospital
  - Bloomington, Illinois, Forenede Stater, 61704
    - Illinois CancerCare-Bloomington
  - Burr Ridge, Illinois, Forenede Stater, 60527
    - Loyola Center for Health at Burr Ridge
  - Canton, Illinois, Forenede Stater, 61520
    - Illinois CancerCare-Canton
  - Carbondale, Illinois, Forenede Stater, 62902
    - Memorial Hospital of Carbondale
  - Carterville, Illinois, Forenede Stater, 62918
    - SIH Cancer Institute
  - Carthage, Illinois, Forenede Stater, 62321
    - Illinois CancerCare-Carthage
  - Centralia, Illinois, Forenede Stater, 62801
    - Centralia Oncology Clinic
  - Centralia, Illinois, Forenede Stater, 62801
    - Saint Mary's Hospital
  - Chicago, Illinois, Forenede Stater, 60611
    - Northwestern University
  - Chicago, Illinois, Forenede Stater, 60612
    - Rush University Medical Center
  - Chicago, Illinois, Forenede Stater, 60637
    - University of Chicago Comprehensive Cancer Center
  - Chicago, Illinois, Forenede Stater, 60612
    - John H Stroger Jr Hospital of Cook County
  - Chicago, Illinois, Forenede Stater, 60625
    - Swedish Covenant Hospital
  - Chicago, Illinois, Forenede Stater, 60657
    - Advocate Illinois Masonic Medical Center
  - Chicago, Illinois, Forenede Stater, 60612
    - Jesse Brown Veterans Affairs Medical Center
  - Crystal Lake, Illinois, Forenede Stater, 60014
    - AMG Crystal Lake - Oncology
  - Danville, Illinois, Forenede Stater, 61832
    - Carle at The Riverfront
  - Decatur, Illinois, Forenede Stater, 62526
    - Decatur Memorial Hospital
  - Decatur, Illinois, Forenede Stater, 62526
    - Cancer Care Specialists of Illinois - Decatur
  - Dixon, Illinois, Forenede Stater, 61021
    - Illinois CancerCare-Dixon
  - Downers Grove, Illinois, Forenede Stater, 60515
    - Advocate Good Samaritan Hospital
  - Effingham, Illinois, Forenede Stater, 62401
    - Crossroads Cancer Center
  - Effingham, Illinois, Forenede Stater, 62401
    - Carle Physician Group-Effingham
  - Elgin, Illinois, Forenede Stater, 60123
    - Advocate Sherman Hospital
  - Elmhurst, Illinois, Forenede Stater, 60126
    - Elmhurst Memorial Hospital
  - Eureka, Illinois, Forenede Stater, 61530
    - Illinois CancerCare-Eureka
  - Evanston, Illinois, Forenede Stater, 60201
    - NorthShore University HealthSystem-Evanston Hospital
  - Freeport, Illinois, Forenede Stater, 61032
    - Freeport Memorial Hospital/Leonard C Ferguson Cancer Center
  - Galesburg, Illinois, Forenede Stater, 61401
    - Western Illinois Cancer Treatment Center
  - Galesburg, Illinois, Forenede Stater, 61401
    - Illinois CancerCare-Galesburg
  - Glenview, Illinois, Forenede Stater, 60026
    - NorthShore University HealthSystem-Glenbrook Hospital
  - Hazel Crest, Illinois, Forenede Stater, 60429
    - Advocate South Suburban Hospital
  - Highland Park, Illinois, Forenede Stater, 60035
    - NorthShore University HealthSystem-Highland Park Hospital
  - Hines, Illinois, Forenede Stater, 60141
    - Edward Hines Jr VA Hospital
  - Hinsdale, Illinois, Forenede Stater, 60521
    - AMITA Health Cancer Institute and Outpatient Center
  - Homer Glen, Illinois, Forenede Stater, 60491
    - Loyola Medicine Homer Glen
  - Joliet, Illinois, Forenede Stater, 60435
    - Duly Health and Care Joliet
  - Kewanee, Illinois, Forenede Stater, 61443
    - Illinois CancerCare-Kewanee Clinic
  - Lake Forest, Illinois, Forenede Stater, 60045
    - Northwestern Medicine Lake Forest Hospital
  - Libertyville, Illinois, Forenede Stater, 60048
    - Condell Memorial Hospital
  - Libertyville, Illinois, Forenede Stater, 60048
    - AMG Libertyville - Oncology
  - Macomb, Illinois, Forenede Stater, 61455
    - Illinois CancerCare-Macomb
  - Mattoon, Illinois, Forenede Stater, 61938
    - Carle Physician Group-Mattoon/Charleston
  - Maywood, Illinois, Forenede Stater, 60153
    - Loyola University Medical Center
  - Melrose Park, Illinois, Forenede Stater, 60160
    - Marjorie Weinberg Cancer Center at Loyola-Gottlieb
  - Mount Vernon, Illinois, Forenede Stater, 62864
    - Good Samaritan Regional Health Center
  - Naperville, Illinois, Forenede Stater, 60540
    - Edward Hospital/Cancer Center
  - New Lenox, Illinois, Forenede Stater, 60451
    - UC Comprehensive Cancer Center at Silver Cross
  - O'Fallon, Illinois, Forenede Stater, 62269
    - Cancer Care Center of O'Fallon
  - O'Fallon, Illinois, Forenede Stater, 62269
    - HSHS Saint Elizabeth's Hospital
  - Oak Lawn, Illinois, Forenede Stater, 60453-2699
    - Advocate Christ Medical Center
  - Orland Park, Illinois, Forenede Stater, 60462
    - University of Chicago Medicine-Orland Park
  - Orland Park, Illinois, Forenede Stater, 60462
    - Northwestern Medicine Orland Park
  - Ottawa, Illinois, Forenede Stater, 61350
    - Illinois CancerCare-Ottawa Clinic
  - Park Ridge, Illinois, Forenede Stater, 60068
    - Advocate Lutheran General Hospital
  - Pekin, Illinois, Forenede Stater, 61554
    - Illinois CancerCare-Pekin
  - Peoria, Illinois, Forenede Stater, 61636
    - Methodist Medical Center of Illinois
  - Peoria, Illinois, Forenede Stater, 61615
    - Illinois CancerCare-Peoria
  - Peru, Illinois, Forenede Stater, 61354
    - Illinois CancerCare-Peru
  - Peru, Illinois, Forenede Stater, 61354
    - Valley Radiation Oncology
  - Plainfield, Illinois, Forenede Stater, 60585
    - Edward Hospital/Cancer Center?Plainfield
  - Princeton, Illinois, Forenede Stater, 61356
    - Illinois CancerCare-Princeton
  - Rockford, Illinois, Forenede Stater, 61114
    - SwedishAmerican Regional Cancer Center/ACT
  - Springfield, Illinois, Forenede Stater, 62781
    - Memorial Medical Center
  - Springfield, Illinois, Forenede Stater, 62702
    - Southern Illinois University School of Medicine
  - Springfield, Illinois, Forenede Stater, 62702
    - Springfield Clinic
  - Swansea, Illinois, Forenede Stater, 62226
    - Southwest Illinois Health Services LLP
  - Urbana, Illinois, Forenede Stater, 61801
    - Carle Cancer Center
  - Urbana, Illinois, Forenede Stater, 61801
    - The Carle Foundation Hospital
  - Washington, Illinois, Forenede Stater, 61571
    - Illinois CancerCare - Washington
  - Yorkville, Illinois, Forenede Stater, 60560
    - Rush-Copley Healthcare Center
- Indiana
  - Richmond, Indiana, Forenede Stater, 47374
    - Reid Health
- Iowa
  - Ames, Iowa, Forenede Stater, 50010
    - Mary Greeley Medical Center
  - Ames, Iowa, Forenede Stater, 50010
    - McFarland Clinic - Ames
  - Ankeny, Iowa, Forenede Stater, 50023
    - Mission Cancer and Blood - Ankeny
  - Bettendorf, Iowa, Forenede Stater, 52722
    - University of Iowa Healthcare Cancer Services Quad Cities
  - Boone, Iowa, Forenede Stater, 50036
    - McFarland Clinic - Boone
  - Carroll, Iowa, Forenede Stater, 51401
    - Saint Anthony Regional Hospital
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Mercy Hospital
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Oncology Associates at Mercy Medical Center
  - Clive, Iowa, Forenede Stater, 50325
    - Mercy Cancer Center-West Lakes
  - Clive, Iowa, Forenede Stater, 50325
    - Medical Oncology and Hematology Associates-West Des Moines
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Alegent Health Mercy Hospital
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Heartland Oncology and Hematology LLP
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Methodist Jennie Edmundson Hospital
  - Creston, Iowa, Forenede Stater, 50801
    - Greater Regional Medical Center
  - Des Moines, Iowa, Forenede Stater, 50309
    - Iowa Methodist Medical Center
  - Des Moines, Iowa, Forenede Stater, 50314
    - Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forenede Stater, 50309
    - Medical Oncology and Hematology Associates-Des Moines
  - Des Moines, Iowa, Forenede Stater, 50314
    - Broadlawns Medical Center
  - Des Moines, Iowa, Forenede Stater, 50314
    - Mission Cancer and Blood - Laurel
  - Des Moines, Iowa, Forenede Stater, 50316
    - Iowa Lutheran Hospital
  - Fort Dodge, Iowa, Forenede Stater, 50501
    - Trinity Regional Medical Center
  - Fort Dodge, Iowa, Forenede Stater, 50501
    - McFarland Clinic - Trinity Cancer Center
  - Iowa City, Iowa, Forenede Stater, 52242
    - University of Iowa/Holden Comprehensive Cancer Center
  - Jefferson, Iowa, Forenede Stater, 50129
    - McFarland Clinic - Jefferson
  - Marshalltown, Iowa, Forenede Stater, 50158
    - McFarland Clinic - Marshalltown
  - Sioux City, Iowa, Forenede Stater, 51101
    - Siouxland Regional Cancer Center
  - Waterloo, Iowa, Forenede Stater, 50702
    - MercyOne Waterloo Cancer Center
  - West Des Moines, Iowa, Forenede Stater, 50266-7700
    - Methodist West Hospital
  - West Des Moines, Iowa, Forenede Stater, 50266
    - Mercy Medical Center-West Lakes
- Kansas
  - Chanute, Kansas, Forenede Stater, 66720
    - Cancer Center of Kansas - Chanute
  - Coffeyville, Kansas, Forenede Stater, 67337
    - Coffeyville Regional Medical Center
  - Dodge City, Kansas, Forenede Stater, 67801
    - Cancer Center of Kansas - Dodge City
  - El Dorado, Kansas, Forenede Stater, 67042
    - Cancer Center of Kansas - El Dorado
  - Fairway, Kansas, Forenede Stater, 66205
    - University of Kansas Clinical Research Center
  - Garden City, Kansas, Forenede Stater, 67846
    - Central Care Cancer Center - Garden City
  - Great Bend, Kansas, Forenede Stater, 67530
    - Central Care Cancer Center - Great Bend
  - Hays, Kansas, Forenede Stater, 67601
    - HaysMed University of Kansas Health System
  - Independence, Kansas, Forenede Stater, 67301
    - Cancer Center of Kansas-Independence
  - Kansas City, Kansas, Forenede Stater, 66112
    - University of Kansas Cancer Center-West
  - Kingman, Kansas, Forenede Stater, 67068
    - Cancer Center of Kansas-Kingman
  - Lawrence, Kansas, Forenede Stater, 66044
    - Lawrence Memorial Hospital
  - Liberal, Kansas, Forenede Stater, 67905
    - Cancer Center of Kansas-Liberal
  - Manhattan, Kansas, Forenede Stater, 66502
    - Cancer Center of Kansas-Manhattan
  - McPherson, Kansas, Forenede Stater, 67460
    - Cancer Center of Kansas - McPherson
  - Newton, Kansas, Forenede Stater, 67114
    - Cancer Center of Kansas - Newton
  - Olathe, Kansas, Forenede Stater, 66061
    - Olathe Health Cancer Center
  - Overland Park, Kansas, Forenede Stater, 66210
    - University of Kansas Cancer Center-Overland Park
  - Overland Park, Kansas, Forenede Stater, 66213
    - Saint Luke's South Hospital
  - Parsons, Kansas, Forenede Stater, 67357
    - Cancer Center of Kansas - Parsons
  - Pittsburg, Kansas, Forenede Stater, 66762
    - Ascension Via Christi - Pittsburg
  - Pittsburg, Kansas, Forenede Stater, 66762
    - Freeman Physician Group of Pittsburg
  - Pratt, Kansas, Forenede Stater, 67124
    - Cancer Center of Kansas - Pratt
  - Salina, Kansas, Forenede Stater, 67401
    - Salina Regional Health Center
  - Salina, Kansas, Forenede Stater, 67401
    - Cancer Center of Kansas - Salina
  - Topeka, Kansas, Forenede Stater, 66606
    - University of Kansas Health System Saint Francis Campus
  - Wellington, Kansas, Forenede Stater, 67152
    - Cancer Center of Kansas - Wellington
  - Westwood, Kansas, Forenede Stater, 66205
    - University of Kansas Hospital-Westwood Cancer Center
  - Wichita, Kansas, Forenede Stater, 67214
    - Ascension Via Christi Hospitals Wichita
  - Wichita, Kansas, Forenede Stater, 67208
    - Cancer Center of Kansas-Wichita Medical Arts Tower
  - Wichita, Kansas, Forenede Stater, 67214
    - Cancer Center of Kansas - Wichita
  - Winfield, Kansas, Forenede Stater, 67156
    - Cancer Center of Kansas - Winfield
- Kentucky
  - Bardstown, Kentucky, Forenede Stater, 40004
    - Flaget Memorial Hospital
  - Corbin, Kentucky, Forenede Stater, 40701
    - Commonwealth Cancer Center-Corbin
  - Lexington, Kentucky, Forenede Stater, 40504
    - Saint Joseph Radiation Oncology Resource Center
  - Lexington, Kentucky, Forenede Stater, 40509
    - Saint Joseph Hospital East
  - Lexington, Kentucky, Forenede Stater, 40504
    - Saint Joseph Hospital
  - London, Kentucky, Forenede Stater, 40741
    - Saint Joseph London
  - Louisville, Kentucky, Forenede Stater, 40202
    - Jewish Hospital
  - Louisville, Kentucky, Forenede Stater, 40245
    - UofL Health Medical Center Northeast
  - Louisville, Kentucky, Forenede Stater, 40215
    - Saints Mary and Elizabeth Hospital
  - Mount Sterling, Kentucky, Forenede Stater, 40353
    - Saint Joseph Mount Sterling
  - Paducah, Kentucky, Forenede Stater, 42003
    - Mercy Health - Paducah Medical Oncology and Hematology
  - Shepherdsville, Kentucky, Forenede Stater, 40165
    - Jewish Hospital Medical Center South
- Louisiana
  - Marrero, Louisiana, Forenede Stater, 70072
    - West Jefferson Medical Center
  - Monroe, Louisiana, Forenede Stater, 71202
    - Ochsner LSU Health Monroe Medical Center
  - New Orleans, Louisiana, Forenede Stater, 70112
    - University Medical Center New Orleans
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Louisiana State University Health Science Center
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Veteran's Administration Medical Center - New Orleans
  - Shreveport, Louisiana, Forenede Stater, 71103
    - LSU Health Sciences Center at Shreveport
- Maine
  - Bangor, Maine, Forenede Stater, 04401
    - Eastern Maine Medical Center
  - Brewer, Maine, Forenede Stater, 04412
    - Lafayette Family Cancer Center-EMMC
- Maryland
  - Baltimore, Maryland, Forenede Stater, 21237
    - MedStar Franklin Square Medical Center/Weinberg Cancer Institute
  - Baltimore, Maryland, Forenede Stater, 21287
    - Johns Hopkins University/Sidney Kimmel Cancer Center
  - Baltimore, Maryland, Forenede Stater, 21204
    - Greater Baltimore Medical Center
  - Baltimore, Maryland, Forenede Stater, 21239
    - MedStar Good Samaritan Hospital
  - Easton, Maryland, Forenede Stater, 21601
    - University of Maryland Shore Medical Center at Easton
  - Elkton, Maryland, Forenede Stater, 21921
    - Christiana Care - Union Hospital
- Massachusetts
  - Beverly, Massachusetts, Forenede Stater, 01915
    - Beverly Hospital
  - Burlington, Massachusetts, Forenede Stater, 01805
    - Lahey Hospital and Medical Center
  - Gloucester, Massachusetts, Forenede Stater, 01930
    - Addison Gilbert Hospital
  - Lowell, Massachusetts, Forenede Stater, 01854
    - Lowell General Hospital
  - Peabody, Massachusetts, Forenede Stater, 01960
    - Lahey Medical Center-Peabody
  - Springfield, Massachusetts, Forenede Stater, 01199
    - Baystate Medical Center
  - Springfield, Massachusetts, Forenede Stater, 01104
    - Mercy Medical Center
  - Winchester, Massachusetts, Forenede Stater, 01890
    - Winchester Hospital
  - Worcester, Massachusetts, Forenede Stater, 01655
    - UMass Memorial Medical Center - University Campus
- Michigan
  - Adrian, Michigan, Forenede Stater, 49221
    - Hickman Cancer Center
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - Saint Joseph Mercy Hospital
  - Battle Creek, Michigan, Forenede Stater, 49017
    - Bronson Battle Creek
  - Brighton, Michigan, Forenede Stater, 48114
    - Saint Joseph Mercy Brighton
  - Brighton, Michigan, Forenede Stater, 48114
    - Trinity Health IHA Medical Group Hematology Oncology - Brighton
  - Canton, Michigan, Forenede Stater, 48188
    - Saint Joseph Mercy Canton
  - Canton, Michigan, Forenede Stater, 48188
    - Trinity Health IHA Medical Group Hematology Oncology - Canton
  - Caro, Michigan, Forenede Stater, 48723
    - Caro Cancer Center
  - Chelsea, Michigan, Forenede Stater, 48118
    - Saint Joseph Mercy Chelsea
  - Chelsea, Michigan, Forenede Stater, 48118
    - Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
  - Clarkston, Michigan, Forenede Stater, 48346
    - Hematology Oncology Consultants-Clarkston
  - Clarkston, Michigan, Forenede Stater, 48346
    - Newland Medical Associates-Clarkston
  - Clarkston, Michigan, Forenede Stater, 48346
    - Michigan Healthcare Professionals Clarkston
  - Detroit, Michigan, Forenede Stater, 48236
    - Ascension Saint John Hospital
  - East China Township, Michigan, Forenede Stater, 48054
    - Great Lakes Cancer Management Specialists-Doctors Park
  - Escanaba, Michigan, Forenede Stater, 49829
    - Green Bay Oncology - Escanaba
  - Farmington Hills, Michigan, Forenede Stater, 48334
    - Michigan Healthcare Professionals Farmington
  - Flint, Michigan, Forenede Stater, 48503
    - Hurley Medical Center
  - Flint, Michigan, Forenede Stater, 48503
    - Genesee Cancer and Blood Disease Treatment Center
  - Flint, Michigan, Forenede Stater, 48503
    - Genesee Hematology Oncology PC
  - Flint, Michigan, Forenede Stater, 48503
    - Genesys Hurley Cancer Institute
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Spectrum Health at Butterworth Campus
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Helen DeVos Children's Hospital at Spectrum Health
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - Trinity Health Grand Rapids Hospital
  - Grosse Pointe Woods, Michigan, Forenede Stater, 48236
    - Academic Hematology Oncology Specialists
  - Grosse Pointe Woods, Michigan, Forenede Stater, 48236
    - Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
  - Grosse Pointe Woods, Michigan, Forenede Stater, 48236
    - Michigan Breast Specialists-Grosse Pointe Woods
  - Kalamazoo, Michigan, Forenede Stater, 49007
    - West Michigan Cancer Center
  - Kalamazoo, Michigan, Forenede Stater, 49007
    - Bronson Methodist Hospital
  - Kalamazoo, Michigan, Forenede Stater, 49048
    - Borgess Medical Center
  - Kalamazoo, Michigan, Forenede Stater, 49009
    - Ascension Borgess Cancer Center
  - Lansing, Michigan, Forenede Stater, 48912
    - University of Michigan Health - Sparrow Lansing
  - Livonia, Michigan, Forenede Stater, 48154
    - Trinity Health Saint Mary Mercy Livonia Hospital
  - Livonia, Michigan, Forenede Stater, 48154
    - Hope Cancer Clinic
  - Macomb, Michigan, Forenede Stater, 48044
    - Great Lakes Cancer Management Specialists-Macomb Medical Campus
  - Macomb, Michigan, Forenede Stater, 48044
    - Michigan Breast Specialists-Macomb Township
  - Macomb, Michigan, Forenede Stater, 48044
    - Michigan Healthcare Professionals Macomb
  - Madison Heights, Michigan, Forenede Stater, 48071
    - Michigan Healthcare Professionals Madison Heights
  - Marlette, Michigan, Forenede Stater, 48453
    - Saint Mary's Oncology/Hematology Associates of Marlette
  - Monroe, Michigan, Forenede Stater, 48162
    - Toledo Clinic Cancer Centers-Monroe
  - Muskegon, Michigan, Forenede Stater, 49444
    - Trinity Health Muskegon Hospital
  - Niles, Michigan, Forenede Stater, 49120
    - Corewell Health Lakeland Hospitals - Niles Hospital
  - Norton Shores, Michigan, Forenede Stater, 49444
    - Cancer and Hematology Centers of Western Michigan - Norton Shores
  - Novi, Michigan, Forenede Stater, 48374
    - Ascension Providence Hospitals - Novi
  - Pontiac, Michigan, Forenede Stater, 48341
    - Saint Joseph Mercy Oakland
  - Pontiac, Michigan, Forenede Stater, 48341
    - 21st Century Oncology-Pontiac
  - Pontiac, Michigan, Forenede Stater, 48341
    - Hope Cancer Center
  - Pontiac, Michigan, Forenede Stater, 48341
    - Newland Medical Associates-Pontiac
  - Port Huron, Michigan, Forenede Stater, 48060
    - Lake Huron Medical Center
  - Port Huron, Michigan, Forenede Stater, 48060
    - Huron Medical Center PC
  - Reed City, Michigan, Forenede Stater, 49677
    - Corewell Health Reed City Hospital
  - Rochester Hills, Michigan, Forenede Stater, 48309
    - Great Lakes Cancer Management Specialists-Rochester Hills
  - Saginaw, Michigan, Forenede Stater, 48601
    - Ascension Saint Mary's Hospital
  - Saginaw, Michigan, Forenede Stater, 48604
    - Oncology Hematology Associates of Saginaw Valley PC
  - Saint Joseph, Michigan, Forenede Stater, 49085
    - Lakeland Medical Center Saint Joseph
  - Saint Joseph, Michigan, Forenede Stater, 49085
    - Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
  - Southfield, Michigan, Forenede Stater, 48075
    - Ascension Providence Hospitals - Southfield
  - Sterling Heights, Michigan, Forenede Stater, 48312
    - Bhadresh Nayak MD PC-Sterling Heights
  - Tawas City, Michigan, Forenede Stater, 48764
    - Ascension Saint Joseph Hospital
  - Traverse City, Michigan, Forenede Stater, 49684
    - Munson Medical Center
  - Troy, Michigan, Forenede Stater, 48098
    - GenesisCare USA - Troy
  - Warren, Michigan, Forenede Stater, 48093
    - Saint John Macomb-Oakland Hospital
  - Warren, Michigan, Forenede Stater, 48088
    - Advanced Breast Care Center PLLC
  - Warren, Michigan, Forenede Stater, 48093
    - Great Lakes Cancer Management Specialists-Macomb Professional Building
  - Warren, Michigan, Forenede Stater, 48093
    - Macomb Hematology Oncology PC
  - Warren, Michigan, Forenede Stater, 48093
    - Michigan Breast Specialists-Warren
  - West Branch, Michigan, Forenede Stater, 48661
    - Saint Mary's Oncology/Hematology Associates of West Branch
  - Wyoming, Michigan, Forenede Stater, 49519
    - University of Michigan Health - West
  - Ypsilanti, Michigan, Forenede Stater, 48197
    - Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
  - Ypsilanti, Michigan, Forenede Stater, 48106
    - Huron Gastroenterology PC
- Minnesota
  - Aitkin, Minnesota, Forenede Stater, 56431
    - Riverwood Healthcare Center
  - Albert Lea, Minnesota, Forenede Stater, 56007
    - Mayo Clinic Health System in Albert Lea
  - Baxter, Minnesota, Forenede Stater, 56425
    - Essentia Health - Baxter Clinic
  - Bemidji, Minnesota, Forenede Stater, 56601
    - Sanford Joe Lueken Cancer Center
  - Brainerd, Minnesota, Forenede Stater, 56401
    - Essentia Health Saint Joseph's Medical Center
  - Burnsville, Minnesota, Forenede Stater, 55337
    - Fairview Ridges Hospital
  - Burnsville, Minnesota, Forenede Stater, 55337
    - Minnesota Oncology - Burnsville
  - Cambridge, Minnesota, Forenede Stater, 55008
    - Cambridge Medical Center
  - Coon Rapids, Minnesota, Forenede Stater, 55433
    - Mercy Hospital
  - Deer River, Minnesota, Forenede Stater, 56636
    - Essentia Health - Deer River Clinic
  - Detroit Lakes, Minnesota, Forenede Stater, 56501
    - Essentia Health Saint Mary's - Detroit Lakes Clinic
  - Duluth, Minnesota, Forenede Stater, 55805
    - Essentia Health Cancer Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - Essentia Health Saint Mary's Medical Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - Miller-Dwan Hospital
  - Edina, Minnesota, Forenede Stater, 55435
    - Fairview Southdale Hospital
  - Ely, Minnesota, Forenede Stater, 55731
    - Essentia Health - Ely Clinic
  - Fergus Falls, Minnesota, Forenede Stater, 56537
    - Lake Region Healthcare Corporation-Cancer Care
  - Fosston, Minnesota, Forenede Stater, 56542
    - Essentia Health - Fosston
  - Fridley, Minnesota, Forenede Stater, 55432
    - Unity Hospital
  - Hibbing, Minnesota, Forenede Stater, 55746
    - Essentia Health Hibbing Clinic
  - International Falls, Minnesota, Forenede Stater, 56649
    - Essentia Health - International Falls Clinic
  - Mankato, Minnesota, Forenede Stater, 56001
    - Mayo Clinic Health Systems-Mankato
  - Maple Grove, Minnesota, Forenede Stater, 55369
    - Fairview Clinics and Surgery Center Maple Grove
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Saint John's Hospital - Healtheast
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Minnesota Oncology Hematology PA-Maplewood
  - Minneapolis, Minnesota, Forenede Stater, 55415
    - Hennepin County Medical Center
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Abbott-Northwestern Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55454
    - Health Partners Inc
  - Minneapolis, Minnesota, Forenede Stater, 55417
    - Minneapolis VA Medical Center
  - Monticello, Minnesota, Forenede Stater, 55362
    - Monticello Cancer Center
  - Moose Lake, Minnesota, Forenede Stater, 55767
    - Essentia Health - Moose Lake Clinic
  - New Ulm, Minnesota, Forenede Stater, 56073
    - New Ulm Medical Center
  - Park Rapids, Minnesota, Forenede Stater, 56470
    - Essentia Health - Park Rapids
  - Princeton, Minnesota, Forenede Stater, 55371
    - Fairview Northland Medical Center
  - Robbinsdale, Minnesota, Forenede Stater, 55422
    - North Memorial Medical Health Center
  - Rochester, Minnesota, Forenede Stater, 55905
    - Mayo Clinic in Rochester
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - Park Nicollet Clinic - Saint Louis Park
  - Saint Paul, Minnesota, Forenede Stater, 55101
    - Regions Hospital
  - Saint Paul, Minnesota, Forenede Stater, 55102
    - United Hospital
  - Sandstone, Minnesota, Forenede Stater, 55072
    - Essentia Health Sandstone
  - Shakopee, Minnesota, Forenede Stater, 55379
    - Saint Francis Regional Medical Center
  - Stillwater, Minnesota, Forenede Stater, 55082
    - Lakeview Hospital
  - Thief River Falls, Minnesota, Forenede Stater, 56701
    - Sanford Thief River Falls Medical Center
  - Virginia, Minnesota, Forenede Stater, 55792
    - Essentia Health Virginia Clinic
  - Waconia, Minnesota, Forenede Stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forenede Stater, 56201
    - Rice Memorial Hospital
  - Woodbury, Minnesota, Forenede Stater, 55125
    - Minnesota Oncology Hematology PA-Woodbury
  - Worthington, Minnesota, Forenede Stater, 56187
    - Sanford Cancer Center Worthington
  - Wyoming, Minnesota, Forenede Stater, 55092
    - Fairview Lakes Medical Center
- Mississippi
  - Columbus, Mississippi, Forenede Stater, 39705
    - Baptist Memorial Hospital and Cancer Center-Golden Triangle
  - Grenada, Mississippi, Forenede Stater, 38901
    - Baptist Cancer Center-Grenada
  - New Albany, Mississippi, Forenede Stater, 38652
    - Baptist Memorial Hospital and Cancer Center-Union County
  - Oxford, Mississippi, Forenede Stater, 38655
    - Baptist Memorial Hospital and Cancer Center-Oxford
  - Pascagoula, Mississippi, Forenede Stater, 39581
    - Singing River Hospital
  - Southhaven, Mississippi, Forenede Stater, 38671
    - Baptist Memorial Hospital and Cancer Center-Desoto
- Missouri
  - Ballwin, Missouri, Forenede Stater, 63011
    - Saint Louis Cancer and Breast Institute-Ballwin
  - Bolivar, Missouri, Forenede Stater, 65613
    - Central Care Cancer Center - Bolivar
  - Bonne Terre, Missouri, Forenede Stater, 63628
    - Parkland Health Center-Bonne Terre
  - Branson, Missouri, Forenede Stater, 65616
    - Cox Cancer Center Branson
  - Cape Girardeau, Missouri, Forenede Stater, 63703
    - Saint Francis Medical Center
  - Cape Girardeau, Missouri, Forenede Stater, 63703
    - Southeast Cancer Center
  - Chesterfield, Missouri, Forenede Stater, 63017
    - Saint Luke's Hospital
  - Farmington, Missouri, Forenede Stater, 63640
    - Parkland Health Center - Farmington
  - Jefferson City, Missouri, Forenede Stater, 65109
    - Capital Region Southwest Campus
  - Joplin, Missouri, Forenede Stater, 64804
    - Freeman Health System
  - Joplin, Missouri, Forenede Stater, 64804
    - Mercy Hospital Joplin
  - Kansas City, Missouri, Forenede Stater, 64154
    - University of Kansas Cancer Center - North
  - Kansas City, Missouri, Forenede Stater, 64131
    - The University of Kansas Cancer Center-South
  - Kansas City, Missouri, Forenede Stater, 64111
    - Saint Luke's Hospital of Kansas City
  - Kansas City, Missouri, Forenede Stater, 64108
    - Truman Medical Centers
  - Lee's Summit, Missouri, Forenede Stater, 64064
    - University of Kansas Cancer Center - Lee's Summit
  - Lee's Summit, Missouri, Forenede Stater, 64086
    - Saint Luke's East - Lee's Summit
  - North Kansas City, Missouri, Forenede Stater, 64116
    - University of Kansas Cancer Center at North Kansas City Hospital
  - Osage Beach, Missouri, Forenede Stater, 65065
    - Lake Regional Hospital
  - Rolla, Missouri, Forenede Stater, 65401
    - Delbert Day Cancer Institute at PCRMC
  - Rolla, Missouri, Forenede Stater, 65401
    - Mercy Clinic-Rolla-Cancer and Hematology
  - Saint Joseph, Missouri, Forenede Stater, 64506
    - Heartland Regional Medical Center
  - Saint Louis, Missouri, Forenede Stater, 63131
    - Missouri Baptist Medical Center
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Mercy Hospital Saint Louis
  - Saint Louis, Missouri, Forenede Stater, 63128
    - Mercy Hospital South
  - Saint Louis, Missouri, Forenede Stater, 63109
    - Saint Louis Cancer and Breast Institute-South City
  - Sainte Genevieve, Missouri, Forenede Stater, 63670
    - Sainte Genevieve County Memorial Hospital
  - Springfield, Missouri, Forenede Stater, 65807
    - CoxHealth South Hospital
  - Springfield, Missouri, Forenede Stater, 65804
    - Mercy Hospital Springfield
  - Sullivan, Missouri, Forenede Stater, 63080
    - Missouri Baptist Sullivan Hospital
  - Sunset Hills, Missouri, Forenede Stater, 63127
    - BJC Outpatient Center at Sunset Hills
  - Washington, Missouri, Forenede Stater, 63090
    - Mercy Hospital Washington
- Montana
  - Anaconda, Montana, Forenede Stater, 59711
    - Community Hospital of Anaconda
  - Billings, Montana, Forenede Stater, 59101
    - Billings Clinic Cancer Center
  - Billings, Montana, Forenede Stater, 59101
    - Saint Vincent Healthcare
  - Billings, Montana, Forenede Stater, 59102
    - Saint Vincent Frontier Cancer Center
  - Bozeman, Montana, Forenede Stater, 59715
    - Bozeman Deaconess Hospital
  - Butte, Montana, Forenede Stater, 59701
    - Saint James Community Hospital and Cancer Treatment Center
  - Great Falls, Montana, Forenede Stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forenede Stater, 59405
    - Benefis Healthcare- Sletten Cancer Institute
  - Helena, Montana, Forenede Stater, 59601
    - Saint Peter's Community Hospital
  - Kalispell, Montana, Forenede Stater, 59901
    - Kalispell Regional Medical Center
  - Missoula, Montana, Forenede Stater, 59804
    - Community Medical Hospital
  - Missoula, Montana, Forenede Stater, 59802
    - Saint Patrick Hospital - Community Hospital
- Nebraska
  - Bellevue, Nebraska, Forenede Stater, 68123
    - Nebraska Medicine-Bellevue
  - Grand Island, Nebraska, Forenede Stater, 68803
    - CHI Health Saint Francis
  - Kearney, Nebraska, Forenede Stater, 68847
    - CHI Health Good Samaritan
  - Kearney, Nebraska, Forenede Stater, 68845
    - Heartland Hematology and Oncology
  - Lincoln, Nebraska, Forenede Stater, 68510
    - Saint Elizabeth Regional Medical Center
  - Omaha, Nebraska, Forenede Stater, 68114
    - Nebraska Methodist Hospital
  - Omaha, Nebraska, Forenede Stater, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forenede Stater, 68124
    - Alegent Health Bergan Mercy Medical Center
  - Omaha, Nebraska, Forenede Stater, 68118
    - Nebraska Medicine-Village Pointe
  - Omaha, Nebraska, Forenede Stater, 68122
    - Alegent Health Immanuel Medical Center
  - Omaha, Nebraska, Forenede Stater, 68130
    - Alegent Health Lakeside Hospital
  - Omaha, Nebraska, Forenede Stater, 68131
    - Creighton University Medical Center
  - Omaha, Nebraska, Forenede Stater, 68122
    - Hematology and Oncology Consultants PC
  - Omaha, Nebraska, Forenede Stater, 68114
    - Oncology Associates PC
  - Omaha, Nebraska, Forenede Stater, 68114
    - Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
  - Papillion, Nebraska, Forenede Stater, 68046
    - Midlands Community Hospital
- Nevada
  - Carson City, Nevada, Forenede Stater, 89703
    - Carson Tahoe Regional Medical Center
  - Henderson, Nevada, Forenede Stater, 89052
    - Comprehensive Cancer Centers of Nevada - Henderson
  - Henderson, Nevada, Forenede Stater, 89052
    - OptumCare Cancer Care at Seven Hills
  - Henderson, Nevada, Forenede Stater, 89052
    - Cancer and Blood Specialists-Henderson
  - Henderson, Nevada, Forenede Stater, 89052
    - Las Vegas Cancer Center-Henderson
  - Henderson, Nevada, Forenede Stater, 89074
    - Comprehensive Cancer Centers of Nevada-Southeast Henderson
  - Henderson, Nevada, Forenede Stater, 89074
    - GenesisCare USA - Henderson
  - Henderson, Nevada, Forenede Stater, 89052
    - Comprehensive Cancer Centers of Nevada-Horizon Ridge
  - Henderson, Nevada, Forenede Stater, 89074
    - Las Vegas Urology - Green Valley
  - Henderson, Nevada, Forenede Stater, 89074
    - Las Vegas Urology - Pebble
  - Henderson, Nevada, Forenede Stater, 89074
    - Urology Specialists of Nevada - Green Valley
  - Las Vegas, Nevada, Forenede Stater, 89144
    - Summerlin Hospital Medical Center
  - Las Vegas, Nevada, Forenede Stater, 89109
    - Sunrise Hospital and Medical Center
  - Las Vegas, Nevada, Forenede Stater, 89102
    - OptumCare Cancer Care at Charleston
  - Las Vegas, Nevada, Forenede Stater, 89106
    - Radiation Oncology Centers of Nevada Central
  - Las Vegas, Nevada, Forenede Stater, 89109
    - GenesisCare USA - Las Vegas
  - Las Vegas, Nevada, Forenede Stater, 89119
    - Radiation Oncology Centers of Nevada Southeast
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Comprehensive Cancer Centers of Nevada - Northwest
  - Las Vegas, Nevada, Forenede Stater, 89128
    - OptumCare Cancer Care at MountainView
  - Las Vegas, Nevada, Forenede Stater, 89135
    - Alliance for Childhood Diseases/Cure 4 the Kids Foundation
  - Las Vegas, Nevada, Forenede Stater, 89144
    - Comprehensive Cancer Centers of Nevada - Town Center
  - Las Vegas, Nevada, Forenede Stater, 89144
    - Comprehensive Cancer Centers of Nevada-Summerlin
  - Las Vegas, Nevada, Forenede Stater, 89148
    - Comprehensive Cancer Centers of Nevada
  - Las Vegas, Nevada, Forenede Stater, 89148
    - OptumCare Cancer Care at Fort Apache
  - Las Vegas, Nevada, Forenede Stater, 89169
    - Comprehensive Cancer Centers of Nevada - Central Valley
  - Las Vegas, Nevada, Forenede Stater, 89102
    - University Medical Center of Southern Nevada
  - Las Vegas, Nevada, Forenede Stater, 89106
    - Cancer and Blood Specialists-Shadow
  - Las Vegas, Nevada, Forenede Stater, 89109
    - HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
  - Las Vegas, Nevada, Forenede Stater, 89113
    - HealthCare Partners Medical Group Oncology/Hematology-San Martin
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Cancer and Blood Specialists-Tenaya
  - Las Vegas, Nevada, Forenede Stater, 89128
    - GenesisCare USA - Vegas Tenaya
  - Las Vegas, Nevada, Forenede Stater, 89128
    - HealthCare Partners Medical Group Oncology/Hematology-Tenaya
  - Las Vegas, Nevada, Forenede Stater, 89148-2405
    - Las Vegas Cancer Center-Medical Center
  - Las Vegas, Nevada, Forenede Stater, 89148
    - GenesisCare USA - Fort Apache
  - Las Vegas, Nevada, Forenede Stater, 89149
    - HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Ann M Wierman MD LTD
  - Las Vegas, Nevada, Forenede Stater, 89074
    - Las Vegas Urology - Pecos
  - Las Vegas, Nevada, Forenede Stater, 89102
    - Desert West Surgery
  - Las Vegas, Nevada, Forenede Stater, 89103
    - Hope Cancer Care of Nevada
  - Las Vegas, Nevada, Forenede Stater, 89106
    - Urology Specialists of Nevada - Central
  - Las Vegas, Nevada, Forenede Stater, 89113
    - Las Vegas Prostate Cancer Center
  - Las Vegas, Nevada, Forenede Stater, 89113
    - Las Vegas Urology - Sunset
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Las Vegas Urology - Cathedral Rock
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Las Vegas Urology - Smoke Ranch
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Urology Specialists of Nevada - Northwest
  - Las Vegas, Nevada, Forenede Stater, 89169
    - University Cancer Center
  - Las Vegas, Nevada, Forenede Stater, 89113
    - Urology Specialists of Nevada - Southwest
  - Pahrump, Nevada, Forenede Stater, 89048
    - Hope Cancer Care of Nevada-Pahrump
  - Reno, Nevada, Forenede Stater, 89502
    - Renown Regional Medical Center
  - Reno, Nevada, Forenede Stater, 89503
    - Saint Mary's Regional Medical Center
  - Reno, Nevada, Forenede Stater, 89509
    - Radiation Oncology Associates
- New Hampshire
  - Concord, New Hampshire, Forenede Stater, 03301
    - New Hampshire Oncology Hematology PA-Concord
  - Lebanon, New Hampshire, Forenede Stater, 03756
    - Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
  - Manchester, New Hampshire, Forenede Stater, 03103
    - Solinsky Center for Cancer Care
  - Manchester, New Hampshire, Forenede Stater, 03103
    - Elliot Hospital
- New Jersey
  - Moorestown, New Jersey, Forenede Stater, 08057
    - Virtua Samson Cancer Center
  - Morristown, New Jersey, Forenede Stater, 07960
    - Morristown Medical Center
  - Mullica Hill, New Jersey, Forenede Stater, 08062
    - Inspira Medical Center Mullica Hill
  - Summit, New Jersey, Forenede Stater, 07902
    - Overlook Hospital
  - Voorhees, New Jersey, Forenede Stater, 08043
    - Virtua Voorhees
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87102
    - University of New Mexico Cancer Center
- New York
  - Auburn, New York, Forenede Stater, 13021
    - Hematology Oncology Associates of Central New York-Auburn
  - Binghamton, New York, Forenede Stater, 13905
    - Lourdes Hospital
  - Bronx, New York, Forenede Stater, 10461
    - Montefiore Medical Center-Einstein Campus
  - Bronx, New York, Forenede Stater, 10467
    - Montefiore Medical Center - Moses Campus
  - Bronx, New York, Forenede Stater, 10461
    - Montefiore Medical Center-Weiler Hospital
  - Bronx, New York, Forenede Stater, 10468
    - James J Peters VA Medical Center
  - East Syracuse, New York, Forenede Stater, 13057
    - Hematology Oncology Associates of Central New York-East Syracuse
  - Glens Falls, New York, Forenede Stater, 12801
    - Glens Falls Hospital
  - New York, New York, Forenede Stater, 10019
    - Mount Sinai West
  - New York, New York, Forenede Stater, 10029
    - Mount Sinai Hospital
  - New York, New York, Forenede Stater, 10011
    - Mount Sinai Chelsea
  - New York, New York, Forenede Stater, 10016
    - Laura and Isaac Perlmutter Cancer Center at NYU Langone
  - Oswego, New York, Forenede Stater, 13126
    - Upstate Cancer Center at Oswego
  - Rochester, New York, Forenede Stater, 14642
    - University of Rochester
  - Stony Brook, New York, Forenede Stater, 11794
    - Stony Brook University Medical Center
  - Syracuse, New York, Forenede Stater, 13210
    - State University of New York Upstate Medical University
  - Syracuse, New York, Forenede Stater, 13215
    - Hematology Oncology Associates of Central New York-Onondaga Hill
  - Syracuse, New York, Forenede Stater, 13215
    - SUNY Upstate Medical Center-Community Campus
  - Verona, New York, Forenede Stater, 13478
    - Upstate Cancer Center at Verona
  - Webster, New York, Forenede Stater, 14580
    - Wilmot Cancer Institute at Webster
- North Carolina
  - Albemarle, North Carolina, Forenede Stater, 28002
    - Atrium Health Stanly/LCI-Albemarle
  - Asheville, North Carolina, Forenede Stater, 28801
    - Mission Hospital
  - Asheville, North Carolina, Forenede Stater, 28803
    - AdventHealth Infusion Center Asheville
  - Chapel Hill, North Carolina, Forenede Stater, 27599
    - UNC Lineberger Comprehensive Cancer Center
  - Charlotte, North Carolina, Forenede Stater, 28203
    - Carolinas Medical Center/Levine Cancer Institute
  - Charlotte, North Carolina, Forenede Stater, 28210
    - Atrium Health Pineville/LCI-Pineville
  - Charlotte, North Carolina, Forenede Stater, 28262
    - Atrium Health University City/LCI-University
  - Charlotte, North Carolina, Forenede Stater, 28211
    - Levine Cancer Institute-SouthPark
  - Charlotte, North Carolina, Forenede Stater, 28277
    - Levine Cancer Institute-Ballantyne
  - Clinton, North Carolina, Forenede Stater, 28328
    - Southeastern Medical Oncology Center-Clinton
  - Clyde, North Carolina, Forenede Stater, 28721
    - AdventHealth Infusion Center Haywood
  - Concord, North Carolina, Forenede Stater, 28025
    - Atrium Health Cabarrus/LCI-Concord
  - Durham, North Carolina, Forenede Stater, 27705
    - Durham VA Medical Center
  - Forest City, North Carolina, Forenede Stater, 28043
    - Levine Cancer Institute - Rutherford
  - Gastonia, North Carolina, Forenede Stater, 28054
    - Levine Cancer Institute-Gaston
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Southeastern Medical Oncology Center-Goldsboro
  - Greenville, North Carolina, Forenede Stater, 27834
    - East Carolina University
  - Hendersonville, North Carolina, Forenede Stater, 28791
    - Margaret R Pardee Memorial Hospital
  - Hendersonville, North Carolina, Forenede Stater, 28792
    - AdventHealth Hendersonville
  - Jacksonville, North Carolina, Forenede Stater, 28546
    - Southeastern Medical Oncology Center-Jacksonville
  - Kenansville, North Carolina, Forenede Stater, 28349
    - Vidant Oncology-Kenansville
  - Kinston, North Carolina, Forenede Stater, 28501
    - Vidant Oncology-Kinston
  - Lincolnton, North Carolina, Forenede Stater, 28092
    - Atrium Health Lincoln/LCI-Lincolnton
  - Matthews, North Carolina, Forenede Stater, 28104
    - Levine Cancer Institute - Union West
  - Monroe, North Carolina, Forenede Stater, 28112
    - Atrium Health Union/LCI-Union
  - Richlands, North Carolina, Forenede Stater, 28574
    - Vidant Oncology-Richlands
  - Salisbury, North Carolina, Forenede Stater, 28144
    - WG Hefner VA Medical Center
  - Shelby, North Carolina, Forenede Stater, 28150
    - Atrium Health Cleveland/LCI-Cleveland
  - Weaverville, North Carolina, Forenede Stater, 28787
    - AdventHealth Infusion Center Weaverville
- North Dakota
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Sanford Bismarck Medical Center
  - Fargo, North Dakota, Forenede Stater, 58122
    - Sanford Roger Maris Cancer Center
  - Fargo, North Dakota, Forenede Stater, 58103
    - Essentia Health Cancer Center-South University Clinic
  - Fargo, North Dakota, Forenede Stater, 58122
    - Sanford Broadway Medical Center
  - Fargo, North Dakota, Forenede Stater, 58103
    - Sanford South University Medical Center
  - Fargo, North Dakota, Forenede Stater, 58103
    - Southpointe-Sanford Medical Center Fargo
  - Fargo, North Dakota, Forenede Stater, 58104
    - Sanford Medical Center Fargo
  - Jamestown, North Dakota, Forenede Stater, 58401
    - Essentia Health - Jamestown Clinic
- Ohio
  - Avon, Ohio, Forenede Stater, 44011
    - UH Seidman Cancer Center at UH Avon Health Center
  - Beachwood, Ohio, Forenede Stater, 44122
    - UHHS-Chagrin Highlands Medical Center
  - Beavercreek, Ohio, Forenede Stater, 45431
    - Indu and Raj Soin Medical Center
  - Belpre, Ohio, Forenede Stater, 45714
    - Strecker Cancer Center-Belpre
  - Boardman, Ohio, Forenede Stater, 44512
    - Saint Elizabeth Boardman Hospital
  - Canton, Ohio, Forenede Stater, 44708
    - Cleveland Clinic Mercy Hospital
  - Canton, Ohio, Forenede Stater, 44708
    - Mercy Hematology and Oncology Associates Inc
  - Centerville, Ohio, Forenede Stater, 45459
    - Miami Valley Hospital South
  - Centerville, Ohio, Forenede Stater, 45459
    - Dayton Physicians LLC-Miami Valley South
  - Chardon, Ohio, Forenede Stater, 44024
    - Geauga Hospital
  - Chillicothe, Ohio, Forenede Stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forenede Stater, 45219
    - University of Cincinnati Cancer Center-UC Medical Center
  - Cincinnati, Ohio, Forenede Stater, 45220
    - Good Samaritan Hospital - Cincinnati
  - Cincinnati, Ohio, Forenede Stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forenede Stater, 45236
    - Oncology Hematology Care Inc-Kenwood
  - Cincinnati, Ohio, Forenede Stater, 45247
    - TriHealth Cancer Institute-Westside
  - Cincinnati, Ohio, Forenede Stater, 45255
    - TriHealth Cancer Institute-Anderson
  - Cleveland, Ohio, Forenede Stater, 44106
    - Case Western Reserve University
  - Cleveland, Ohio, Forenede Stater, 44109
    - MetroHealth Medical Center
  - Cleveland, Ohio, Forenede Stater, 44195
    - Cleveland Clinic Foundation
  - Cleveland, Ohio, Forenede Stater, 44111
    - Cleveland Clinic Cancer Center/Fairview Hospital
  - Columbus, Ohio, Forenede Stater, 43214
    - Riverside Methodist Hospital
  - Columbus, Ohio, Forenede Stater, 43210
    - Ohio State University Comprehensive Cancer Center
  - Columbus, Ohio, Forenede Stater, 43219
    - The Mark H Zangmeister Center
  - Columbus, Ohio, Forenede Stater, 43214
    - Columbus Oncology and Hematology Associates Inc
  - Columbus, Ohio, Forenede Stater, 43228
    - Doctors Hospital
  - Columbus, Ohio, Forenede Stater, 43213
    - Mount Carmel East Hospital
  - Columbus, Ohio, Forenede Stater, 43215
    - Grant Medical Center
  - Columbus, Ohio, Forenede Stater, 43222
    - Mount Carmel Health Center West
  - Dayton, Ohio, Forenede Stater, 45406
    - Good Samaritan Hospital - Dayton
  - Dayton, Ohio, Forenede Stater, 45409
    - Miami Valley Hospital
  - Dayton, Ohio, Forenede Stater, 45415
    - Dayton Physician LLC-Miami Valley Hospital North
  - Dayton, Ohio, Forenede Stater, 45415
    - Miami Valley Hospital North
  - Dayton, Ohio, Forenede Stater, 45409
    - Dayton Blood and Cancer Center
  - Delaware, Ohio, Forenede Stater, 43015
    - Delaware Health Center-Grady Cancer Center
  - Delaware, Ohio, Forenede Stater, 43015
    - Grady Memorial Hospital
  - Dublin, Ohio, Forenede Stater, 43016
    - Dublin Methodist Hospital
  - Dublin, Ohio, Forenede Stater, 43016
    - Columbus Oncology and Hematology Associates
  - Elyria, Ohio, Forenede Stater, 44035
    - Mercy Cancer Center-Elyria
  - Findlay, Ohio, Forenede Stater, 45840
    - Blanchard Valley Hospital
  - Findlay, Ohio, Forenede Stater, 45840
    - Armes Family Cancer Center
  - Findlay, Ohio, Forenede Stater, 45840
    - Orion Cancer Care
  - Franklin, Ohio, Forenede Stater, 45005-1066
    - Atrium Medical Center-Middletown Regional Hospital
  - Franklin, Ohio, Forenede Stater, 45005
    - Dayton Physicians LLC-Atrium
  - Gahanna, Ohio, Forenede Stater, 43230
    - Central Ohio Breast and Endocrine Surgery
  - Greenville, Ohio, Forenede Stater, 45331
    - Wayne Hospital
  - Greenville, Ohio, Forenede Stater, 45331
    - Dayton Physicians LLC-Wayne
  - Greenville, Ohio, Forenede Stater, 45331
    - Miami Valley Cancer Care and Infusion
  - Grove City, Ohio, Forenede Stater, 43123
    - Mount Carmel Grove City Hospital
  - Grove City, Ohio, Forenede Stater, 43123
    - Zangmeister Center Grove City
  - Independence, Ohio, Forenede Stater, 44131
    - Cleveland Clinic Cancer Center Independence
  - Kettering, Ohio, Forenede Stater, 45429
    - Kettering Medical Center
  - Kettering, Ohio, Forenede Stater, 45409
    - Greater Dayton Cancer Center
  - Kettering, Ohio, Forenede Stater, 45420
    - First Dayton Cancer Care
  - Lancaster, Ohio, Forenede Stater, 43130
    - Fairfield Medical Center
  - Lima, Ohio, Forenede Stater, 45801
    - Saint Rita's Medical Center
  - Mansfield, Ohio, Forenede Stater, 44906
    - Cleveland Clinic Cancer Center Mansfield
  - Mansfield, Ohio, Forenede Stater, 44903
    - OhioHealth Mansfield Hospital
  - Marietta, Ohio, Forenede Stater, 45750
    - Marietta Memorial Hospital
  - Marion, Ohio, Forenede Stater, 43302
    - OhioHealth Marion General Hospital
  - Marysville, Ohio, Forenede Stater, 43040
    - Memorial Hospital
  - Maumee, Ohio, Forenede Stater, 43537
    - Toledo Clinic Cancer Centers-Maumee
  - Mayfield Heights, Ohio, Forenede Stater, 44124
    - Hillcrest Hospital Cancer Center
  - Mayfield Heights, Ohio, Forenede Stater, 44124
    - UH Seidman Cancer Center at Landerbrook Health Center
  - Mentor, Ohio, Forenede Stater, 44060
    - UH Seidman Cancer Center at Lake Health Mentor Campus
  - Middleburg Heights, Ohio, Forenede Stater, 44130
    - UH Seidman Cancer Center at Southwest General Hospital
  - Mount Vernon, Ohio, Forenede Stater, 43050
    - Knox Community Hospital
  - New Albany, Ohio, Forenede Stater, 43054
    - Mount Carmel New Albany Surgical Hospital
  - Newark, Ohio, Forenede Stater, 43055
    - Licking Memorial Hospital
  - Newark, Ohio, Forenede Stater, 43055
    - Newark Radiation Oncology
  - Parma, Ohio, Forenede Stater, 44129
    - University Hospitals Parma Medical Center
  - Perrysburg, Ohio, Forenede Stater, 43551
    - Mercy Health Perrysburg Cancer Center
  - Portsmouth, Ohio, Forenede Stater, 45662
    - Southern Ohio Medical Center
  - Ravenna, Ohio, Forenede Stater, 44266
    - University Hospitals Portage Medical Center
  - Sandusky, Ohio, Forenede Stater, 44870
    - North Coast Cancer Care
  - Sandusky, Ohio, Forenede Stater, 44870
    - UH Seidman Cancer Center at Firelands Regional Medical Center
  - Springfield, Ohio, Forenede Stater, 45505
    - Springfield Regional Medical Center
  - Springfield, Ohio, Forenede Stater, 45504
    - Springfield Regional Cancer Center
  - Steubenville, Ohio, Forenede Stater, 43952
    - Trinity's Tony Teramana Cancer Center
  - Strongsville, Ohio, Forenede Stater, 44136
    - Cleveland Clinic Cancer Center Strongsville
  - Toledo, Ohio, Forenede Stater, 43608
    - Saint Vincent Mercy Medical Center
  - Toledo, Ohio, Forenede Stater, 43623
    - Mercy Health - Saint Anne Hospital
  - Toledo, Ohio, Forenede Stater, 43623
    - Toledo Clinic Cancer Centers-Toledo
  - Toledo, Ohio, Forenede Stater, 43623
    - Mercy Health Sylvania Radiation Oncology Center
  - Troy, Ohio, Forenede Stater, 45373
    - Upper Valley Medical Center
  - Troy, Ohio, Forenede Stater, 45373
    - Dayton Physicians LLC - Troy
  - Wadsworth, Ohio, Forenede Stater, 44281
    - University Hospitals Sharon Health Center
  - Warren, Ohio, Forenede Stater, 44484
    - Saint Joseph Warren Hospital
  - Warrensville Heights, Ohio, Forenede Stater, 44122
    - South Pointe Hospital
  - West Chester, Ohio, Forenede Stater, 45069
    - University of Cincinnati Cancer Center-West Chester
  - Westerville, Ohio, Forenede Stater, 43081
    - Saint Ann's Hospital
  - Westlake, Ohio, Forenede Stater, 44145
    - UH Seidman Cancer Center at Saint John Medical Center
  - Westlake, Ohio, Forenede Stater, 44145
    - UHHS-Westlake Medical Center
  - Wilmington, Ohio, Forenede Stater, 45177
    - Clinton Memorial Hospital
  - Wooster, Ohio, Forenede Stater, 44691
    - Cleveland Clinic Wooster Family Health and Surgery Center
  - Wright-Patterson Air Force Base, Ohio, Forenede Stater, 45433
    - Wright-Patterson Medical Center
  - Youngstown, Ohio, Forenede Stater, 44501
    - Saint Elizabeth Youngstown Hospital
  - Zanesville, Ohio, Forenede Stater, 43701
    - Genesis Healthcare System Cancer Care Center
- Oklahoma
  - Oklahoma City, Oklahoma, Forenede Stater, 73104
    - University of Oklahoma Health Sciences Center
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Mercy Hospital Oklahoma City
  - Tulsa, Oklahoma, Forenede Stater, 74146
    - Oklahoma Cancer Specialists and Research Institute-Tulsa
- Oregon
  - Baker City, Oregon, Forenede Stater, 97814
    - Saint Alphonsus Medical Center-Baker City
  - Bend, Oregon, Forenede Stater, 97701
    - Saint Charles Health System
  - Clackamas, Oregon, Forenede Stater, 97015
    - Clackamas Radiation Oncology Center
  - Clackamas, Oregon, Forenede Stater, 97015
    - Providence Cancer Institute Clackamas Clinic
  - Coos Bay, Oregon, Forenede Stater, 97420
    - Bay Area Hospital
  - Newberg, Oregon, Forenede Stater, 97132
    - Providence Newberg Medical Center
  - Ontario, Oregon, Forenede Stater, 97914
    - Saint Alphonsus Medical Center-Ontario
  - Oregon City, Oregon, Forenede Stater, 97045
    - Providence Willamette Falls Medical Center
  - Portland, Oregon, Forenede Stater, 97213
    - Providence Portland Medical Center
  - Portland, Oregon, Forenede Stater, 97225
    - Providence Saint Vincent Medical Center
  - Redmond, Oregon, Forenede Stater, 97756
    - Saint Charles Health System-Redmond
- Pennsylvania
  - Allentown, Pennsylvania, Forenede Stater, 18103
    - Lehigh Valley Hospital-Cedar Crest
  - Altoona, Pennsylvania, Forenede Stater, 16601
    - UPMC Altoona
  - Bethel Park, Pennsylvania, Forenede Stater, 15102
    - UPMC Cancer Center-Bethel Park
  - Bethlehem, Pennsylvania, Forenede Stater, 18017
    - Lehigh Valley Hospital - Muhlenberg
  - Bryn Mawr, Pennsylvania, Forenede Stater, 19010
    - Bryn Mawr Hospital
  - Camp Hill, Pennsylvania, Forenede Stater, 17011
    - UPMC Camp Hill
  - Carlisle, Pennsylvania, Forenede Stater, 17015
    - Carlisle Regional Cancer Center
  - Chadds Ford, Pennsylvania, Forenede Stater, 19317
    - Christiana Care Health System-Concord Health Center
  - Chambersburg, Pennsylvania, Forenede Stater, 17201
    - Chambersburg Hospital
  - Chambersburg, Pennsylvania, Forenede Stater, 17201
    - WellSpan Medical Oncology and Hematology
  - East Stroudsburg, Pennsylvania, Forenede Stater, 18301
    - Pocono Medical Center
  - Ephrata, Pennsylvania, Forenede Stater, 17522
    - Ephrata Cancer Center
  - Ephrata, Pennsylvania, Forenede Stater, 17522
    - Ephrata Community Hospital
  - Erie, Pennsylvania, Forenede Stater, 16505
    - UPMC Hillman Cancer Center Erie
  - Gettysburg, Pennsylvania, Forenede Stater, 17325
    - Adams Cancer Center
  - Greensburg, Pennsylvania, Forenede Stater, 15601
    - UPMC Cancer Centers - Arnold Palmer Pavilion
  - Hanover, Pennsylvania, Forenede Stater, 17331
    - Cherry Tree Cancer Center
  - Harrisburg, Pennsylvania, Forenede Stater, 17109
    - UPMC Pinnacle Cancer Center/Community Osteopathic Campus
  - Harrisburg, Pennsylvania, Forenede Stater, 17101
    - UPMC Pinnacle Harrisburg
  - Hazleton, Pennsylvania, Forenede Stater, 18201
    - Lehigh Valley Hospital-Hazleton
  - Lebanon, Pennsylvania, Forenede Stater, 17042
    - Sechler Family Cancer Center
  - McKeesport, Pennsylvania, Forenede Stater, 15132
    - UPMC Cancer Center at UPMC McKeesport
  - Mechanicsburg, Pennsylvania, Forenede Stater, 17050
    - UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
  - Media, Pennsylvania, Forenede Stater, 19063
    - Riddle Memorial Hospital
  - N. Huntingdon, Pennsylvania, Forenede Stater, 15642
    - Arnold Palmer Cancer Center Medical Oncology Norwin
  - Paoli, Pennsylvania, Forenede Stater, 19301
    - Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19111
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19104
    - University of Pennsylvania/Abramson Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19140
    - Temple University Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19104
    - Penn Presbyterian Medical Center
  - Pittsburgh, Pennsylvania, Forenede Stater, 15232
    - University of Pittsburgh Cancer Institute (UPCI)
  - Pittsburgh, Pennsylvania, Forenede Stater, 15215
    - UPMC-Saint Margaret
  - Pittsburgh, Pennsylvania, Forenede Stater, 15237
    - UPMC-Passavant Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15243
    - UPMC-Saint Clair Hospital Cancer Center
  - Pittsburgh, Pennsylvania, Forenede Stater, 15215
    - Oncology Hematology Association
  - Pittsburgh, Pennsylvania, Forenede Stater, 15219
    - UPMC-Mercy Hospital
  - Pottstown, Pennsylvania, Forenede Stater, 19464
    - Pottstown Hospital
  - Seneca, Pennsylvania, Forenede Stater, 16346
    - UPMC Cancer Center at UPMC Northwest
  - Washington, Pennsylvania, Forenede Stater, 15301
    - UPMC Cancer Center-Washington
  - Wynnewood, Pennsylvania, Forenede Stater, 19096
    - Lankenau Medical Center
  - York, Pennsylvania, Forenede Stater, 17403
    - WellSpan Health-York Cancer Center
  - York, Pennsylvania, Forenede Stater, 17403
    - WellSpan Health-York Hospital
  - York, Pennsylvania, Forenede Stater, 17403
    - Cancer Care Associates of York
  - York, Pennsylvania, Forenede Stater, 17408
    - UPMC Memorial
- Rhode Island
  - Warwick, Rhode Island, Forenede Stater, 02886
    - Kent Hospital
  - Westerly, Rhode Island, Forenede Stater, 02891
    - Smilow Cancer Hospital Care Center - Westerly
- South Carolina
  - Bluffton, South Carolina, Forenede Stater, 29910
    - Saint Joseph's/Candler - Bluffton Campus
  - Boiling Springs, South Carolina, Forenede Stater, 29316
    - Prisma Health Cancer Institute - Spartanburg
  - Charleston, South Carolina, Forenede Stater, 29425
    - Medical University of South Carolina
  - Charleston, South Carolina, Forenede Stater, 29401
    - Ralph H Johnson VA Medical Center
  - Columbia, South Carolina, Forenede Stater, 29203
    - Prisma Health Richland Hospital
  - Gaffney, South Carolina, Forenede Stater, 29341
    - Gibbs Cancer Center-Gaffney
  - Georgetown, South Carolina, Forenede Stater, 29440
    - Tidelands Georgetown Memorial Hospital
  - Greenville, South Carolina, Forenede Stater, 29605
    - Prisma Health Cancer Institute - Faris
  - Greenville, South Carolina, Forenede Stater, 29615
    - Prisma Health Cancer Institute - Eastside
  - Greenville, South Carolina, Forenede Stater, 29605
    - Prisma Health Cancer Institute - Butternut
  - Greenville, South Carolina, Forenede Stater, 29605
    - Prisma Health Greenville Memorial Hospital
  - Greenwood, South Carolina, Forenede Stater, 29646
    - Self Regional Healthcare
  - Greer, South Carolina, Forenede Stater, 29650
    - Prisma Health Cancer Institute - Greer
  - Greer, South Carolina, Forenede Stater, 29651
    - Gibbs Cancer Center-Pelham
  - Hilton Head Island, South Carolina, Forenede Stater, 29926-3827
    - South Carolina Cancer Specialists PC
  - Myrtle Beach, South Carolina, Forenede Stater, 29577
    - Carolina Regional Cancer Center
  - Rock Hill, South Carolina, Forenede Stater, 29732
    - Levine Cancer Institute-Rock Hill
  - Seneca, South Carolina, Forenede Stater, 29672
    - Prisma Health Cancer Institute - Seneca
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - Spartanburg Medical Center
  - Spartanburg, South Carolina, Forenede Stater, 29307
    - Spartanburg Medical Center - Mary Black Campus
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - North Grove Medical Park
  - Union, South Carolina, Forenede Stater, 29379
    - MGC Hematology Oncology-Union
- South Dakota
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Rapid City Regional Hospital
  - Sioux Falls, South Dakota, Forenede Stater, 57117-5134
    - Sanford USD Medical Center - Sioux Falls
  - Sioux Falls, South Dakota, Forenede Stater, 57104
    - Sanford Cancer Center Oncology Clinic
- Tennessee
  - Alcoa, Tennessee, Forenede Stater, 37701
    - University Cancer Specialists - Alcoa
  - Bristol, Tennessee, Forenede Stater, 37620
    - Bristol Regional Medical Center
  - Chattanooga, Tennessee, Forenede Stater, 37404
    - Memorial Hospital
  - Collierville, Tennessee, Forenede Stater, 38017
    - Baptist Memorial Hospital and Cancer Center-Collierville
  - Franklin, Tennessee, Forenede Stater, 37067
    - Vanderbilt-Ingram Cancer Center Cool Springs
  - Franklin, Tennessee, Forenede Stater, 37067
    - Vanderbilt-Ingram Cancer Center at Franklin
  - Hixson, Tennessee, Forenede Stater, 37343
    - Pulmonary Medicine Center of Chattanooga-Hixson
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Ballad Health Cancer Care - Kingsport
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Wellmont Holston Valley Hospital and Medical Center
  - Knoxville, Tennessee, Forenede Stater, 37920
    - University of Tennessee - Knoxville
  - Memphis, Tennessee, Forenede Stater, 38120
    - Baptist Memorial Hospital and Cancer Center-Memphis
  - Nashville, Tennessee, Forenede Stater, 37232
    - Vanderbilt University/Ingram Cancer Center
  - Nashville, Tennessee, Forenede Stater, 37204
    - Vanderbilt Breast Center at One Hundred Oaks
  - Ooltewah, Tennessee, Forenede Stater, 37363
    - Memorial GYN Plus
- Texas
  - Baytown, Texas, Forenede Stater, 77521
    - Houston Methodist San Jacinto Hospital
  - Bryan, Texas, Forenede Stater, 77802
    - Saint Joseph Regional Cancer Center
  - Dallas, Texas, Forenede Stater, 75235
    - Parkland Memorial Hospital
  - Dallas, Texas, Forenede Stater, 75390
    - UT Southwestern/Simmons Cancer Center-Dallas
  - Dallas, Texas, Forenede Stater, 75216
    - Dallas VA Medical Center
  - Dallas, Texas, Forenede Stater, 75237
    - UT Southwestern Simmons Cancer Center - RedBird
  - Fort Worth, Texas, Forenede Stater, 76104
    - UT Southwestern/Simmons Cancer Center-Fort Worth
  - Fort Worth, Texas, Forenede Stater, 76104
    - Tarrant County Hospital District/JPS Health Network
  - Houston, Texas, Forenede Stater, 77030
    - Houston Methodist Hospital
  - Houston, Texas, Forenede Stater, 77070
    - Methodist Willowbrook Hospital
  - Houston, Texas, Forenede Stater, 77094
    - Houston Methodist West Hospital
  - Nassau Bay, Texas, Forenede Stater, 77058
    - Houston Methodist Saint John Hospital
  - Richardson, Texas, Forenede Stater, 75080
    - UT Southwestern Clinical Center at Richardson/Plano
  - Sugar Land, Texas, Forenede Stater, 77479
    - Houston Methodist Sugar Land Hospital
  - The Woodlands, Texas, Forenede Stater, 77385
    - Houston Methodist The Woodlands Hospital
- Utah
  - American Fork, Utah, Forenede Stater, 84003
    - American Fork Hospital / Huntsman Intermountain Cancer Center
  - Cedar City, Utah, Forenede Stater, 84720
    - Sandra L Maxwell Cancer Center
  - Logan, Utah, Forenede Stater, 84321
    - Logan Regional Hospital
  - Murray, Utah, Forenede Stater, 84107
    - Intermountain Medical Center
  - Ogden, Utah, Forenede Stater, 84403
    - McKay-Dee Hospital Center
  - Provo, Utah, Forenede Stater, 84604
    - Utah Valley Regional Medical Center
  - Riverton, Utah, Forenede Stater, 84065
    - Riverton Hospital
  - Saint George, Utah, Forenede Stater, 84770
    - Saint George Regional Medical Center
  - Salt Lake City, Utah, Forenede Stater, 84106
    - Utah Cancer Specialists-Salt Lake City
  - Salt Lake City, Utah, Forenede Stater, 84143
    - LDS Hospital
- Vermont
  - Berlin, Vermont, Forenede Stater, 05602
    - Central Vermont Medical Center/National Life Cancer Treatment
  - Burlington, Vermont, Forenede Stater, 05401
    - University of Vermont Medical Center
  - Burlington, Vermont, Forenede Stater, 05405
    - University of Vermont and State Agricultural College
  - Saint Johnsbury, Vermont, Forenede Stater, 05819
    - Norris Cotton Cancer Center-North
- Virginia
  - Bristol, Virginia, Forenede Stater, 24201
    - Wellmont Medical Associates-Bristol
  - Charlottesville, Virginia, Forenede Stater, 22908
    - University of Virginia Cancer Center
  - Fishersville, Virginia, Forenede Stater, 22939
    - Augusta Health Center for Cancer and Blood Disorders
  - Norton, Virginia, Forenede Stater, 24273
    - Southwest VA Regional Cancer Center
  - Richmond, Virginia, Forenede Stater, 23235
    - VCU Massey Cancer Center at Stony Point
  - Richmond, Virginia, Forenede Stater, 23298
    - Virginia Commonwealth University/Massey Cancer Center
  - Richmond, Virginia, Forenede Stater, 23229
    - Virginia Cancer Institute
  - South Hill, Virginia, Forenede Stater, 23970
    - VCU Community Memorial Health Center
- Washington
  - Aberdeen, Washington, Forenede Stater, 98520
    - Providence Regional Cancer System-Aberdeen
  - Auburn, Washington, Forenede Stater, 98001
    - MultiCare Auburn Medical Center
  - Bellevue, Washington, Forenede Stater, 98004
    - Overlake Medical Center
  - Bellingham, Washington, Forenede Stater, 98225
    - PeaceHealth Saint Joseph Medical Center
  - Bremerton, Washington, Forenede Stater, 98310
    - Harrison HealthPartners Hematology and Oncology-Bremerton
  - Bremerton, Washington, Forenede Stater, 98310
    - Harrison Medical Center
  - Burien, Washington, Forenede Stater, 98166
    - Highline Medical Center-Main Campus
  - Centralia, Washington, Forenede Stater, 98531
    - Providence Regional Cancer System-Centralia
  - Edmonds, Washington, Forenede Stater, 98026
    - Swedish Cancer Institute-Edmonds
  - Enumclaw, Washington, Forenede Stater, 98022
    - Saint Elizabeth Hospital
  - Everett, Washington, Forenede Stater, 98201
    - Providence Regional Cancer Partnership
  - Federal Way, Washington, Forenede Stater, 98003
    - Saint Francis Hospital
  - Gig Harbor, Washington, Forenede Stater, 98335
    - MultiCare Gig Harbor Medical Park
  - Issaquah, Washington, Forenede Stater, 98029
    - Swedish Cancer Institute-Issaquah
  - Kennewick, Washington, Forenede Stater, 99336
    - Kadlec Clinic Hematology and Oncology
  - Lacey, Washington, Forenede Stater, 98503
    - Providence Regional Cancer System-Lacey
  - Lakewood, Washington, Forenede Stater, 98499
    - Saint Clare Hospital
  - Longview, Washington, Forenede Stater, 98632
    - PeaceHealth Saint John Medical Center
  - Port Townsend, Washington, Forenede Stater, 98368
    - Jefferson Healthcare
  - Poulsbo, Washington, Forenede Stater, 98370
    - Harrison HealthPartners Hematology and Oncology-Poulsbo
  - Puyallup, Washington, Forenede Stater, 98372
    - MultiCare Good Samaritan Hospital
  - Renton, Washington, Forenede Stater, 98055
    - Valley Medical Center
  - Seattle, Washington, Forenede Stater, 98107
    - Swedish Medical Center-Ballard Campus
  - Seattle, Washington, Forenede Stater, 98122
    - Swedish Medical Center-First Hill
  - Seattle, Washington, Forenede Stater, 98112
    - Kaiser Permanente Washington
  - Seattle, Washington, Forenede Stater, 98104
    - Pacific Gynecology Specialists
  - Seattle, Washington, Forenede Stater, 98122-5711
    - Swedish Medical Center-Cherry Hill
  - Sedro-Woolley, Washington, Forenede Stater, 98284
    - PeaceHealth United General Medical Center
  - Shelton, Washington, Forenede Stater, 98584
    - Providence Regional Cancer System-Shelton
  - Spokane, Washington, Forenede Stater, 99204
    - MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
  - Spokane, Washington, Forenede Stater, 99218
    - MultiCare Deaconess Cancer and Blood Specialty Center - North
  - Spokane Valley, Washington, Forenede Stater, 99216
    - MultiCare Deaconess Cancer and Blood Specialty Center - Valley
  - Tacoma, Washington, Forenede Stater, 98405
    - Mary Bridge Children's Hospital and Health Center
  - Tacoma, Washington, Forenede Stater, 98405
    - Northwest Medical Specialties PLLC
  - Tacoma, Washington, Forenede Stater, 98405
    - MultiCare Tacoma General Hospital
  - Tacoma, Washington, Forenede Stater, 98405
    - Franciscan Research Center-Northwest Medical Plaza
  - Vancouver, Washington, Forenede Stater, 98664
    - PeaceHealth Southwest Medical Center
  - Walla Walla, Washington, Forenede Stater, 99362
    - Providence Saint Mary Regional Cancer Center
  - Yakima, Washington, Forenede Stater, 98902
    - North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
  - Yelm, Washington, Forenede Stater, 98597
    - Providence Regional Cancer System-Yelm
- West Virginia
  - Charleston, West Virginia, Forenede Stater, 25304
    - West Virginia University Charleston Division
  - Huntington, West Virginia, Forenede Stater, 25701
    - Edwards Comprehensive Cancer Center
- Wisconsin
  - Antigo, Wisconsin, Forenede Stater, 54409
    - Langlade Hospital and Cancer Center
  - Appleton, Wisconsin, Forenede Stater, 54915
    - Ascension Saint Elizabeth Hospital
  - Ashland, Wisconsin, Forenede Stater, 54806
    - Duluth Clinic Ashland
  - Ashland, Wisconsin, Forenede Stater, 54806
    - Northwest Wisconsin Cancer Center
  - Baraboo, Wisconsin, Forenede Stater, 53913
    - SSM Health Dean Medical Group - Baraboo
  - Brookfield, Wisconsin, Forenede Stater, 53045
    - Ascension Southeast Wisconsin Hospital - Elmbrook Campus
  - Burlington, Wisconsin, Forenede Stater, 53105
    - Aurora Cancer Care-Southern Lakes VLCC
  - Chilton, Wisconsin, Forenede Stater, 53014
    - Ascension Calumet Hospital
  - Cudahy, Wisconsin, Forenede Stater, 53110
    - Aurora Saint Luke's South Shore
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - Marshfield Medical Center-EC Cancer Center
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - HSHS Sacred Heart Hospital
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - Mayo Clinic Health System-Eau Claire Clinic
  - Eau Claire, Wisconsin, Forenede Stater, 54703
    - Mayo Clinic Health System Eau Claire Hospital-Luther Campus
  - Fond Du Lac, Wisconsin, Forenede Stater, 54937
    - Aurora Health Center-Fond du Lac
  - Franklin, Wisconsin, Forenede Stater, 53132
    - Ascension Saint Francis - Reiman Cancer Center
  - Germantown, Wisconsin, Forenede Stater, 53022
    - Aurora Health Care Germantown Health Center
  - Grafton, Wisconsin, Forenede Stater, 53024
    - Aurora Cancer Care-Grafton
  - Green Bay, Wisconsin, Forenede Stater, 54311
    - Aurora BayCare Medical Center
  - Green Bay, Wisconsin, Forenede Stater, 54301
    - Saint Vincent Hospital Cancer Center Green Bay
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - Saint Vincent Hospital Cancer Center at Saint Mary's
  - Hayward, Wisconsin, Forenede Stater, 54843
    - Essentia Health-Hayward Clinic
  - Janesville, Wisconsin, Forenede Stater, 53548
    - Mercyhealth Hospital and Cancer Center - Janesville
  - Janesville, Wisconsin, Forenede Stater, 53546
    - SSM Health Dean Medical Group - Janesville
  - Kenosha, Wisconsin, Forenede Stater, 53142
    - Aurora Cancer Care-Kenosha South
  - La Crosse, Wisconsin, Forenede Stater, 54601
    - Gundersen Lutheran Medical Center
  - La Crosse, Wisconsin, Forenede Stater, 54601
    - Mayo Clinic Health System-Franciscan Healthcare
  - Madison, Wisconsin, Forenede Stater, 53717
    - Dean Hematology and Oncology Clinic
  - Madison, Wisconsin, Forenede Stater, 53792
    - University of Wisconsin Carbone Cancer Center
  - Manitowoc, Wisconsin, Forenede Stater, 54221
    - Holy Family Memorial Hospital
  - Marinette, Wisconsin, Forenede Stater, 54143
    - Aurora Bay Area Medical Group-Marinette
  - Marinette, Wisconsin, Forenede Stater, 54143
    - Saint Vincent Hospital Cancer Center at Marinette
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - Marshfield Medical Center-Marshfield
  - Medford, Wisconsin, Forenede Stater, 54451
    - Aspirus Medford Hospital
  - Mequon, Wisconsin, Forenede Stater, 53097
    - Ascension Columbia Saint Mary's Hospital Ozaukee
  - Milwaukee, Wisconsin, Forenede Stater, 53209
    - Aurora Cancer Care-Milwaukee
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Aurora Saint Luke's Medical Center
  - Milwaukee, Wisconsin, Forenede Stater, 53233
    - Aurora Sinai Medical Center
  - Milwaukee, Wisconsin, Forenede Stater, 53211
    - Ascension Columbia Saint Mary's Hospital - Milwaukee
  - Minocqua, Wisconsin, Forenede Stater, 54548
    - Marshfield Clinic-Minocqua Center
  - Mukwonago, Wisconsin, Forenede Stater, 53149
    - ProHealth D N Greenwald Center
  - New Richmond, Wisconsin, Forenede Stater, 54017
    - Cancer Center of Western Wisconsin
  - Oconomowoc, Wisconsin, Forenede Stater, 53066
    - ProHealth Oconomowoc Memorial Hospital
  - Oconto Falls, Wisconsin, Forenede Stater, 54154
    - Saint Vincent Hospital Cancer Center at Oconto Falls
  - Oshkosh, Wisconsin, Forenede Stater, 54904
    - Ascension Mercy Hospital
  - Oshkosh, Wisconsin, Forenede Stater, 54904
    - Vince Lombardi Cancer Clinic - Oshkosh
  - Racine, Wisconsin, Forenede Stater, 53406
    - Aurora Cancer Care-Racine
  - Racine, Wisconsin, Forenede Stater, 53405
    - Ascension All Saints Hospital
  - Rhinelander, Wisconsin, Forenede Stater, 54501
    - Ascension Saint Mary's Hospital
  - Rice Lake, Wisconsin, Forenede Stater, 54868
    - Marshfield Medical Center-Rice Lake
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - Vince Lombardi Cancer Clinic-Sheboygan
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - HSHS Saint Nicholas Hospital
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - Saint Vincent Hospital Cancer Center at Sheboygan
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - Sheboygan Phyisicans Group
  - Spooner, Wisconsin, Forenede Stater, 54801
    - Essentia Health-Spooner Clinic
  - Stevens Point, Wisconsin, Forenede Stater, 54481
    - Ascension Saint Michael's Hospital
  - Stevens Point, Wisconsin, Forenede Stater, 54482
    - Marshfield Medical Center-River Region at Stevens Point
  - Sturgeon Bay, Wisconsin, Forenede Stater, 54235-1495
    - Saint Vincent Hospital Cancer Center at Sturgeon Bay
  - Summit, Wisconsin, Forenede Stater, 53066
    - Aurora Medical Center in Summit
  - Superior, Wisconsin, Forenede Stater, 54880
    - Essentia Health Saint Mary's Hospital - Superior
  - Two Rivers, Wisconsin, Forenede Stater, 54241
    - Vince Lombardi Cancer Clinic-Two Rivers
  - Waukesha, Wisconsin, Forenede Stater, 53188
    - UW Cancer Center at ProHealth Care
  - Waukesha, Wisconsin, Forenede Stater, 53188
    - ProHealth Waukesha Memorial Hospital
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Aspirus Regional Cancer Center
  - Wauwatosa, Wisconsin, Forenede Stater, 53226
    - Aurora Cancer Care-Milwaukee West
  - Wauwatosa, Wisconsin, Forenede Stater, 53226
    - Ascension Medical Group Southeast Wisconsin - Mayfair Road
  - West Allis, Wisconsin, Forenede Stater, 53227
    - Aurora West Allis Medical Center
  - Weston, Wisconsin, Forenede Stater, 54476
    - Marshfield Medical Center - Weston
  - Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
    - Aspirus Cancer Care - Wisconsin Rapids
- Wyoming
  - Cheyenne, Wyoming, Forenede Stater, 82001
    - Cheyenne Regional Medical Center-West
  - Cody, Wyoming, Forenede Stater, 82414
    - Billings Clinic-Cody
  - Sheridan, Wyoming, Forenede Stater, 82801
    - Welch Cancer Center
Guam
- - Tamuning, Guam, 96913
    - FHP Health Center-Guam

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Beskrivelse

Inklusionskriterier:

Patienter skal have histologisk eller cytologisk bekræftet stadium IV ikke-pladecellet ikke-småcellet lungekræft (NSCLC) (inkluderer M1a, M1b og M1c stadium sygdom, American Joint Committee on Cancer [AJCC] 8. udgave). Patienter med stadium IIIB og IIIC sygdom er berettigede, hvis de ikke er kandidater til kombineret kemoterapi og stråling
Patienter skal have PD-L1 ekspression Tumor Proportion Score (TPS) >= 1 % i tumorceller. Hvis PD-L1-ekspressions-TPS ikke kan evalueres, eller testen ikke kunne fuldføres, er patienterne ikke kvalificerede. Analysen skal være udført af et Clinical Laboratory Improvement Act (CLIA) (eller tilsvarende) certificeret laboratorium
Patienter skal have målbar eller ikke-målbar sygdom. Tilstedeværelsen af ondartet pleuravæske alene er tilstrækkelig til at opfylde dette berettigelseskriterium. Baseline billeddannelsesvurderinger og målinger, der bruges til at evaluere alle målbare eller ikke-målbare sygdomssteder, skal udføres inden for 4 uger før undersøgelsesregistrering
- BEMÆRK: Hvis patienten får pemetrexed, skal du følge institutionelle retningslinjer for at dræne væsker
Patienterne skal være >= 18 år
Patienter skal have en Eastern Cooperative Oncology Group (ECOG) præstationsstatus på 0 til 1
Patienter med behandlede hjernemetastaser er berettigede, hvis opfølgende hjernebilleddannelse efter centralnervesystem (CNS)-styret terapi ikke viser tegn på progression. CNS-progression tæller som progression, og patienterne skal gå videre til næste fase efter CNS-behandling. Patienter med asymptomatiske nye (ved screening) eller progressive hjernemetastaser (aktive hjernemetastaser ved screening) eller leptomeningeal sygdom er berettigede, hvis den behandlende læge fastslår, at øjeblikkelig CNS-specifik behandling ikke er påkrævet, og det er usandsynligt, at det er nødvendigt under den første behandlingscyklus.
- Patienter er berettigede, hvis de er afbrudt af steroider i mindst 14 dage før protokolbehandling
- Palliativ stråling til ikke-mållæsioner (knoglemetastaser) er tilladt, hvis patienten udvikler symptomer
- Antikonvulsiva er tilladt
- Patienter med asymptomatisk, sub-centimeter hjernemetastaser, som efter forskeres skøn ikke har behov for øjeblikkelig CNS-styrede terapier, er kvalificerede
Patienter med tidligere eller samtidig malignitet, hvis naturlige historie eller behandling ikke har potentiale til at interferere med sikkerheds- eller effektivitetsvurderingen af undersøgelsesregimet, er kvalificerede til dette forsøg
Patienter med kendt historie eller aktuelle symptomer på hjertesygdom, eller historie med behandling med kardiotoksiske midler, bør have en klinisk risikovurdering af hjertefunktionen ved hjælp af New York Heart Association Functional Classification. For at være berettiget til dette forsøg skal patienter være klasse 2B eller bedre
Kvinder i den fødedygtige alder og seksuelt aktive mænd skal bruge en accepteret og effektiv præventionsmetode eller afholde sig fra samleje fra registreringstidspunktet, mens de er i undersøgelsesbehandling, og fortsætte i 120 dage efter den sidste dosis af undersøgelsesbehandlingen
Absolut neutrofiltal (ANC) >= 1500/mm^3 (inden for 14 dage efter randomisering)
Blodplader >= 100.000/mm^3 (inden for 14 dage efter randomisering)
Protrombintid (PT)/internationalt normaliseret forhold (INR) =< 1,5 Eller hvis patient på terapeutisk antikoagulering, PT/INR =< 3,0 (inden for 14 dage efter randomisering)
Partiel tromboplastintid (PTT) =< institutionel øvre normalgrænse (ULN) ELLER, hvis patienten er på terapeutisk antikoagulering, skal PTT være =< 1,5 x ULN (inden for 14 dage efter randomisering)
Total bilirubin =< 1,5 mg/dL (opnået inden for 14 dage efter randomisering)
Serumglutamin-oxaloeddikesyretransaminase (SGOT) (aspartataminotransferase [AST]) < 5 x øvre normalgrænse (ULN) (opnået inden for 14 dage efter randomisering)
Serumglutamatpyruvattransaminase (SGPT) (alaninaminotransferase [ALT]) < 5 x øvre normalgrænse (ULN) (opnået inden for 14 dage efter randomisering)
Beregnet kreatininclearance >= 45 ml/min for at være berettiget til at modtage pemetrexed (opnået inden for 14 dage før randomisering)
Serumkreatinin =< 1,5 x institutionel øvre normalgrænse (ULN) (opnået inden for 14 dage før randomisering)
Humant immundefektvirus (HIV)-inficerede patienter i effektiv antiretroviral behandling med upåviselig viral belastning inden for 6 måneder er kvalificerede til dette forsøg
For patienter med tegn på kronisk hepatitis B-virus (HBV)-infektion skal HBV-virusmængden være upåviselig eller under suppressiv behandling, hvis indiceret. Patienter med en historie med hepatitis C-virus (HCV)-infektion skal være blevet behandlet og helbredt. For patienter med HCV-infektion, som i øjeblikket er i behandling, er de berettigede, hvis de har en upåviselig HCV-virusbelastning

Ekskluderingskriterier:

Patienter må IKKE have modtaget følgende:
- Tidligere systemisk kemoterapi eller immunterapi til avanceret metastatisk NSCLC. Patienter behandlet med tidligere checkpoint-hæmmere for metastatisk lungekræft er ikke kvalificerede. Kemoterapi til ikke-metastatisk sygdom (f. adjuverende terapi) eller immunterapi for lokalt fremskreden stadium III-sygdom er tilladt, hvis der er gået mindst 6 måneder mellem den sidste dosis af den forudgående terapi og undersøgelsesregistreringen. Lokal terapi, f.eks. palliativ stråling, er tilladt, så længe der er gået 14 dage mellem afslutning af lokal terapi og studieregistrering. Tilmelding inden behandling i de 14 dage er tilladt. Palliativ stråling skal være til ikke-mållæsioner
- Methotrexat (MTX) givet i lave doser til ikke-maligne tilstande med sidste dosis mindst 14 dage før registreringsdatoen er tilladt. Andre lavdosis kemoterapeutika til ikke-maligne tilstande vil blive overvejet, men gennemgang af studielederen er påkrævet
Patienter med kendte EGFR-mutationer (undtagen exon 20-insertion), BRAF-mutationer (V600) eller ALK- eller ROS1-translokationer, der kan behandles med orale tyrosinkinasehæmmere, er udelukket
Patienter må ikke have kendt allerede eksisterende og klinisk aktiv interstitiel lungesygdom eller en kendt anamnese med (ikke-infektiøs) pneumonitis, der krævede steroider, eller aktuel pneumonitis
Patienter må ikke have betydelige gastrointestinale lidelser med diarré som et hovedsymptom (f. Crohns sygdom, malabsorption osv.)
Patienter må ikke have en historie med autoimmun tilstand, der har krævet igangværende eller intermitterende systemisk behandling inden for de seneste 2 år (dvs. med brug af sygdomsmodificerende midler, kortikosteroider eller immunsuppressive lægemidler). Erstatningsterapi (f.eks. thyroxin, insulin eller fysiologisk kortikosteroiderstatningsterapi for binyre- eller hypofyseinsufficiens osv.) betragtes ikke som en form for systemisk behandling
Patienter må ikke have nogen anden samtidig alvorlig sygdom eller dysfunktion i organsystemet, som efter investigatorens opfattelse enten ville kompromittere patientsikkerheden eller forstyrre evalueringen af undersøgelseslægemidlets sikkerhed
Patienter må ikke modtage andre forsøgsmidler i løbet af behandlingen
Kvinder må ikke være gravide eller amme på grund af potentiel skade på fosteret eller spædbarnet fra cytotoksisk kemoterapi og den ukendte risiko for MK-3475 (pembrolizumab). Patienter må heller ikke forvente at blive gravide eller få børn fra registreringstidspunktet, mens de er i undersøgelsesbehandling og indtil mindst 120 dage efter den sidste dosis af undersøgelsesbehandlingen
- Alle kvinder i den fødedygtige alder skal have en blodprøve eller urinundersøgelse inden for 72 timer før registrering for at udelukke graviditet
- En kvinde i den fødedygtige alder er enhver kvinde, uanset seksuel orientering eller om de har gennemgået tubal ligering, som opfylder følgende kriterier: har opnået menarche på et tidspunkt; ikke har gennemgået en hysterektomi eller bilateral oophorektomi; eller ikke har været naturligt postmenopausal (amenoré efter cancerbehandling udelukker ikke den fødedygtige alder) i mindst 24 på hinanden følgende måneder (dvs. har haft menstruation på noget tidspunkt i de foregående 24 på hinanden følgende måneder)
Patienter må ikke have en kendt historie med aktiv tuberkulose (TB)
Patienter må ikke have en diagnose af immundefekt eller modtage systemisk steroidbehandling eller nogen anden form for immunsuppressiv terapi inden for 7 dage før den første dosis af protokolbehandling
Patienter må ikke have modtaget en levende vaccine inden for 30 dage før randomisering. Sæsoninfluenzavacciner, der ikke indeholder levende virus, er tilladt

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Ingen (Åben etiket)

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: Arm A (pembrolizumab, pemetrexed, carboplatin) Patienterne får pembrolizumab IV over 30 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år i fravær af sygdomsprogression eller uacceptabel toksicitet. Inden for 6 uger efter sygdomsprogression får patienterne pemetrexed IV over 10 minutter og carboplatin IV over 30 minutter på dag 1. Behandlingen gentages hver 21. dag i op til 4 cyklusser i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienter kan derefter få pemetrexed IV over 10 minutter på dag 1. Cykler gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienter gennemgår MR under screening, CT-scanning og blodprøvetagning under hele undersøgelsen og kan gennemgå PET-scanning under hele undersøgelsen.	Medicin: Carboplatin Givet IV Andre navne: Blastocarb Carboplat Carboplatin Hexal Carboplatino Carboplatin Carbosin Carbosol Carbotec CBDCA Displata Ercar JM-8 Nealorin Novoplatin Paraplatin Paraplatin AQ Platinwas Ribocarbo JM8 Procedure: MR scanning Gennemgå MR Andre navne: MR Magnetisk resonans Magnetisk resonansbilledscanning Medicinsk billeddannelse, magnetisk resonans / kernemagnetisk resonans HR MR billeddannelse MR-scanning NMR billeddannelse NMRI Kernemagnetisk resonansbilleddannelse Magnetisk resonansbilleddannelse (MRI) sMRI Magnetisk resonansbilleddannelse (procedure) MRI'er Strukturel MR Biologisk: Pembrolizumab Givet IV Andre navne: Keytruda MK-3475 Lambrolizumab SCH 900475 BCD-201 Pembrolizumab Biosimilar BCD-201 Procedure: Bioprøvesamling Gennemgå blodprøvetagning Andre navne: Biologisk prøvesamling Bioprøve indsamlet Prøvesamling Medicin: Pemetrexed Givet IV Andre navne: MTA Multitarget antifolat Pemfexy Procedure: Positron emissionstomografi Gennemgå PET-scanning Andre navne: Medicinsk billeddannelse, Positron Emission Tomografi KÆLEDYR PET-scanning Positron Emission Tomografi Scan Positron-emissionstomografi proton magnetisk resonans spektroskopisk billeddannelse PT Positron emissionstomografi (procedure) Procedure: Computertomografi Gennemgå CT-scanning Andre navne: CT KAT CAT-scanning Beregnet aksial tomografi Computerstyret aksial tomografi Computerstyret tomografi CT-scanning tomografi Computerstyret aksial tomografi (procedure) Computerstyret tomografi (CT) scanning
Eksperimentel: Arm B (pembrolizumab, pemetrexed, carboplatin) Patienterne får pembrolizumab IV over 30 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år i fravær af sygdomsprogression eller uacceptabel toksicitet. Inden for 6 uger efter sygdomsprogression får patienterne pembrolizumab IV over 30 minutter, pemetrexed IV over 10 minutter og carboplatin IV over 30 minutter på dag 1. Behandlingen gentages hver 21. dag i op til 4 cyklusser i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienterne får derefter pembrolizumab IV over 30 minutter og pemetrexed IV over 10 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år for pembrolizumab i fravær af sygdomsprogression eller uacceptabel toksicitet og indtil sygdomsprogression for pemetrexed. Patienter gennemgår MR under screening, CT-scanning og blodprøvetagning under hele undersøgelsen og kan gennemgå PET-scanning under hele undersøgelsen.	Medicin: Carboplatin Givet IV Andre navne: Blastocarb Carboplat Carboplatin Hexal Carboplatino Carboplatin Carbosin Carbosol Carbotec CBDCA Displata Ercar JM-8 Nealorin Novoplatin Paraplatin Paraplatin AQ Platinwas Ribocarbo JM8 Procedure: MR scanning Gennemgå MR Andre navne: MR Magnetisk resonans Magnetisk resonansbilledscanning Medicinsk billeddannelse, magnetisk resonans / kernemagnetisk resonans HR MR billeddannelse MR-scanning NMR billeddannelse NMRI Kernemagnetisk resonansbilleddannelse Magnetisk resonansbilleddannelse (MRI) sMRI Magnetisk resonansbilleddannelse (procedure) MRI'er Strukturel MR Biologisk: Pembrolizumab Givet IV Andre navne: Keytruda MK-3475 Lambrolizumab SCH 900475 BCD-201 Pembrolizumab Biosimilar BCD-201 Procedure: Bioprøvesamling Gennemgå blodprøvetagning Andre navne: Biologisk prøvesamling Bioprøve indsamlet Prøvesamling Medicin: Pemetrexed Givet IV Andre navne: MTA Multitarget antifolat Pemfexy Procedure: Positron emissionstomografi Gennemgå PET-scanning Andre navne: Medicinsk billeddannelse, Positron Emission Tomografi KÆLEDYR PET-scanning Positron Emission Tomografi Scan Positron-emissionstomografi proton magnetisk resonans spektroskopisk billeddannelse PT Positron emissionstomografi (procedure) Procedure: Computertomografi Gennemgå CT-scanning Andre navne: CT KAT CAT-scanning Beregnet aksial tomografi Computerstyret aksial tomografi Computerstyret tomografi CT-scanning tomografi Computerstyret aksial tomografi (procedure) Computerstyret tomografi (CT) scanning
Aktiv komparator: Arm C (pembrolizumab, pembrolizumab, carboplatin) Patienterne får pembrolizumab IV over 30 minutter, pemetrexed IV over 10 minutter og carboplatin IV over 30 minutter på dag 1. Behandlingen gentages hver 21. dag i op til 4 cyklusser i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienterne får derefter pembrolizumab IV over 30 minutter og pemetrexed IV over 10 minutter på dag 1. Cykler gentages hver 21. dag i op til 2 år for pembrolizumab i fravær af sygdomsprogression eller uacceptabel toksicitet og indtil sygdomsprogression for pemetrexed. Patienter gennemgår MR under screening, CT-scanning og blodprøvetagning under hele undersøgelsen og kan gennemgå PET-scanning under hele undersøgelsen.	Medicin: Carboplatin Givet IV Andre navne: Blastocarb Carboplat Carboplatin Hexal Carboplatino Carboplatin Carbosin Carbosol Carbotec CBDCA Displata Ercar JM-8 Nealorin Novoplatin Paraplatin Paraplatin AQ Platinwas Ribocarbo JM8 Procedure: MR scanning Gennemgå MR Andre navne: MR Magnetisk resonans Magnetisk resonansbilledscanning Medicinsk billeddannelse, magnetisk resonans / kernemagnetisk resonans HR MR billeddannelse MR-scanning NMR billeddannelse NMRI Kernemagnetisk resonansbilleddannelse Magnetisk resonansbilleddannelse (MRI) sMRI Magnetisk resonansbilleddannelse (procedure) MRI'er Strukturel MR Biologisk: Pembrolizumab Givet IV Andre navne: Keytruda MK-3475 Lambrolizumab SCH 900475 BCD-201 Pembrolizumab Biosimilar BCD-201 Procedure: Bioprøvesamling Gennemgå blodprøvetagning Andre navne: Biologisk prøvesamling Bioprøve indsamlet Prøvesamling Medicin: Pemetrexed Givet IV Andre navne: MTA Multitarget antifolat Pemfexy Procedure: Positron emissionstomografi Gennemgå PET-scanning Andre navne: Medicinsk billeddannelse, Positron Emission Tomografi KÆLEDYR PET-scanning Positron Emission Tomografi Scan Positron-emissionstomografi proton magnetisk resonans spektroskopisk billeddannelse PT Positron emissionstomografi (procedure) Procedure: Computertomografi Gennemgå CT-scanning Andre navne: CT KAT CAT-scanning Beregnet aksial tomografi Computerstyret aksial tomografi Computerstyret tomografi CT-scanning tomografi Computerstyret aksial tomografi (procedure) Computerstyret tomografi (CT) scanning

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Samlet overlevelse (OS) Tidsramme: Fra randomisering til død uanset årsag, vurderet op til 5 år efter behandling	OS distributioner vil blive estimeret ved hjælp af Kaplan-Meier metoden.	Fra randomisering til død uanset årsag, vurderet op til 5 år efter behandling

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Progressionsfri overlevelse (PFS) Tidsramme: Fra randomisering til dokumenteret sygdomsprogression eller død uanset årsag, vurderet op til 5 år efter behandling	PFS distributioner vil blive estimeret ved hjælp af Kaplan-Meier metoden.	Fra randomisering til dokumenteret sygdomsprogression eller død uanset årsag, vurderet op til 5 år efter behandling
PD-L1 positivitet Tidsramme: Ved baseline	PD-L1-positivitet vil blive defineret som >= 1 % Tumor Proportion Score (TPS) med henblik på tilmelding til forsøget. Stærkt PD-L1 positiv er defineret som >= 50 % TPS; svagt positiv er defineret som 1% - 49% TPS.	Ved baseline
Bedste objektive svar Tidsramme: Op til 5 år efter behandling	Bedste objektive respons vil blive evalueret via Response Evaluation Criteria in Solid Tumors 1.1 kriterier.	Op til 5 år efter behandling
Forekomst af uønskede hændelser Tidsramme: Op til 30 dage efter behandling	Toksiciteter vil blive rapporteret via de fælles terminologikriterier for bivirkninger, version 5.0. Toksicitetsrater mellem arme i den samlede population vil blive sammenlignet ved hjælp af Fishers eksakte test med en ensidig type I fejlrate på 1,25 %; multivariabel logistisk regressionsmodellering vil blive brugt til at justere for effekten af eventuelle kovariater, der er forbundet med disse kategoriske resultater.	Op til 30 dage efter behandling

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

National Cancer Institute (NCI)

Efterforskere

Ledende efterforsker: Hossein Borghaei, ECOG-ACRIN Cancer Research Group

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

5. april 2019

Primær færdiggørelse (Anslået)

31. december 2028

Studieafslutning (Anslået)

31. december 2028

Datoer for studieregistrering

Først indsendt

3. januar 2019

Først indsendt, der opfyldte QC-kriterier

3. januar 2019

Først opslået (Faktiske)

4. januar 2019

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

24. april 2024

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

23. april 2024

Sidst verificeret

1. marts 2024

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

NCI-2018-03695 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
U10CA180820 (U.S. NIH-bevilling/kontrakt)
EA5163 (Anden identifikator: CTEP)

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

NCI er forpligtet til at dele data i overensstemmelse med NIHs politik. For flere detaljer om, hvordan kliniske forsøgsdata deles, skal du gå til linket til NIH-siden for datadelingspolitik

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ingen

produkt fremstillet i og eksporteret fra U.S.A.

Ingen

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Carboplatin

Eisai Inc.

Afsluttet

En dosisfindende undersøgelse af E7389 i kombination med carboplatin hos patienter med solide tumorer

Kræft

Forenede Stater, Østrig, Indien
Samyang Biopharmaceuticals Corporation

Afsluttet

Bestem MTD, evaluer effektiviteten og sikkerheden af Genexol®-PM Plus Carboplatin med avanceret ovariecancer

Livmoderhalskræft
NHS Greater Glasgow and Clyde

Afsluttet

Carboplatin til behandling af patienter med stadium IC-IV ovarie-, æggeleder- eller primær peritoneal cancer

Livmoderhalskræft | Æggelederkræft | Primær peritoneal kræft

Det Forenede Kongerige, Australien, New Zealand
Duke University

Afsluttet

Carboplatin hos patienter med progressive gliomer

Tumorer i hjernen og centralnervesystemet

Forenede Stater, Canada
National Cancer Institute (NCI)
Children's Oncology Group

Afsluttet

Lobradimil og Carboplatin til behandling af børn med hjernetumorer

Tumorer i hjernen og centralnervesystemet

Forenede Stater, Canada, Puerto Rico, Australien, Holland, New Zealand, Schweiz
All India Institute of Medical Sciences, New Delhi
Council of Scientific and Industrial Research, India

Ukendt

Forsøg, der sammenligner to carboplatindoser i gruppe C og D intraokulært retinoblastom

Intraokulært retinoblastom

Indien
National Cancer Institute (NCI)

Afsluttet

AZD2281 Plus Carboplatin til behandling af bryst- og æggestokkræft

Brystkræft | Livmoderhalskræft

Forenede Stater
Medical Research Council
European Organisation for Research and Treatment of Cancer - EORTC

Afsluttet

Stråleterapi sammenlignet med kemoterapi ved behandling af patienter med trin I testikelkræft

Testikulær kimcelletumor

Det Forenede Kongerige, Canada, Norge, Holland, Sydafrika, Brasilien, Finland
Akeso

Rekruttering

AK112 i kombination med kemoterapi ved avanceret planocellulær ikke-småcellet lungekræft

Avanceret pladeepitel, ikke-småcellet lungekræft

Kina
Rennes University Hospital

Afsluttet

Undersøgelse af prædiktive faktorer for kemoresistens i ovariecancer (FaCliBioCCo)

Livmoderhalskræft

Frankrig

Afprøvning af timingen af ​​Pembrolizumab alene eller med kemoterapi som førstelinjebehandling og vedligeholdelse ved ikke-småcellet lungekræft

EA5163/S1709 INSIGNA: Et randomiseret, fase III-studie af førstelinjeimmunterapi alene eller i kombination med kemoterapi i induktion/vedligeholdelse eller efterprogression ved avanceret ikke-småcellet ikke-småcellet lungekræft (NSCLC) med immunbiomarkør SIGNature-drevet analyse

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Anslået)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Efterforskere

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Anslået)

Studieafslutning (Anslået)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Faktiske)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

produkt fremstillet i og eksporteret fra U.S.A.

Kliniske forsøg med Carboplatin

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Mexico

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer

Afprøvning af timingen af Pembrolizumab alene eller med kemoterapi som førstelinjebehandling og vedligeholdelse ved ikke-småcellet lungekræft