POST CATARACT SURGERY DRY EYE DISEASE

Inclusion Criteria:

• 2. Age: > 18 years and less than 78 years old. 3. Subject who requires a unilateral cataract surgery (phacoemulsification and intra ocular lens implantation) or bilateral cataract surgery with delay of maximum 4 days between two eyes operation.

  4. Subject with mild to moderate dry eye at the pre-operative visit with the following scores:

  • OSDI (Ocular Surface Disease Index) ≥ 13 and ≤ 32
  • Schirmer test in the operated eye ≥ 5 mm/5min and ≤ 15 mm/5min And/or

  • Non-invasive break-up time (NIBUT) in the operated eye: sum of 3 measurement ≥ 5 sec and ≤ 15 sec 5. Patient who did not use artificial tears 1 week before the screening visit. 6. Patient having given freely and expressly his informed consent. 7. Patient psychologically able to understand the study related information and to give a written informed consent.

    8. Female of childbearing potential should use a contraceptive regimen recognized as effective since at least 12 weeks before screening visit, during all the study and at least 1 month after the study end.

Exclusion Criteria:

In terms of population

1. Pregnant or nursing woman or planning a pregnancy during the study.
2. Subject who had been deprived of their freedom by administrative or legal decision or who is under guardianship.
3. Subject in a social or sanitary establishment.
4. Subject suspected to be non-compliant according to the investigator's judgment.

5. Patient using contact lens during screening period and the entire study (even if prescribed by the investigator after surgery).

   In terms of associated pathology

6. Subject with a condition or receiving a medication which, in the investigator's judgment, put the subject at undue risk.
7. Subject with severe eye dryness
8. Patient with palpebral malposition with a tendency to incomplete blinking +/- scleral show
9. Patient with general pathologies that can cause dry eye syndrome like: thyroid disorder, cutaneous rosacea, acne and/or iatrogenic effects of isotretinoin treatment.
10. Presence of ocular comorbidities such as glaucoma, uveitis or cystoid macular oedema.
11. Neuropathic causes of dry eye ( long-standing contact lens wearing, previous ocular herpes infections)
12. Past or active ocular surface diseases (any corneal disease, cicatricial conjunctivitis, ocular surface burns, keratinization of the eyelid margin, Sjogren syndrome, corneal trauma)
13. Ocular or general factors predisposing the patient to an increased risk for intraoperative complications, according to investigator's evaluation
14. Know hypersensitivity to any component of the study product Relating to previous or ongoing treatment
15. Subject with other ocular surgery in the 12 previous months.
16. Subject with lid surgery in the 3 previous months
17. Subject who received systemic non-steroidal anti-inflammatory drugs, immunosuppressants, corticoids or any medication that could interfere with lacrimal function during the 3 weeks prior to the study.
18. Subject who received topical antibiotics, topical NSAIDs, topical steroid or topical cyclosporine in either eye in the past month.