- ICH GCP
- US-Register für klinische Studien
- Klinische Studie NCT07835347
Large Language Models for Stuttering Assessment and Therapy
Alignment of Large Language Model Responses on Stuttering Definition, Assessment, and Therapy With Clinical Practice Guidelines: A Multi-Model Comparison
This observational study aims to compare the quality of responses generated by four large language models (ChatGPT, Claude, Google Gemini, and Grok-4.20) to questions about stuttering. The study focuses on three main areas: general information about stuttering, clinical assessment, and therapy. A total of nine questions were developed based on evidence-based clinical practice guidance, including the American Speech-Language-Hearing Association (ASHA) Practice Portal. Each question is presented to each language model in separate sessions, and the generated responses are recorded for evaluation.
Five speech-language therapists with clinical experience in stuttering independently evaluate the model-generated responses. Each response is rated for relevance, accuracy, clarity, completeness, and consistency using a 5-point Likert scale. The responses are also compared with guideline-based reference information. The study does not involve any clinical intervention or treatment of patients. The aim is to determine how closely large language model responses align with current clinical practice guidance and to identify their potential strengths and limitations when used as informational or clinical support tools in the field of stuttering.
Studienübersicht
Status
Bedingungen
Studientyp
Einschreibung (Tatsächlich)
Kontakte und Standorte
Studienorte
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Istanbul
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Istanbul, Istanbul, Türkei (türkiye), 34310
- Istanbul Gelisim University
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Teilnahmekriterien
Zulassungskriterien
Studienberechtigtes Alter
Akzeptiert gesunde Freiwillige
Studienberechtigte Geschlechter
Probenahmeverfahren
Studienpopulation
The study population consisted of adult speech-language therapists in Türkiye who were actively working in the field of stuttering and fluency disorders. Five speech-language therapists with clinical experience in stuttering were purposively selected to independently evaluate responses generated by four large language models to standardized questions concerning stuttering information, assessment, and therapy.
Beschreibung
Inclusion Criteria:
- Having an undergraduate or postgraduate degree in speech and language therapy.
- Actively practicing clinically in the field of stuttering/fluency disorders.
- Voluntarily agreeing to participate in the study.
- Completing the evaluation form in full.
Exclusion Criteria:
- Not having active clinical experience in the field of stuttering.
- Incomplete completion of the evaluation form.
- Withdrawal of voluntary participation during the evaluation process.
Studienplan
Wie ist die Studie aufgebaut?
Designdetails
- Beobachtungsmodelle: OTHER
- Zeitperspektiven: CROSS_SECTIONAL
Kohorten und Interventionen
Gruppe / Kohorte |
Intervention / Behandlung |
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Expert Speech-Language Therapists
Five speech-language therapists with clinical experience in stuttering independently evaluated responses generated by four large language models (ChatGPT, Claude, Google Gemini, and Grok-4.20). The responses addressed nine questions covering general information about stuttering, clinical assessment, and therapy. Each response was rated for relevance, accuracy, clarity, completeness, and consistency using a 5-point Likert scale. |
ChatGPT responses to nine standardized questions on stuttering information, assessment, and therapy were generated in separate sessions and recorded for independent expert evaluation. Questions were repeated under comparable conditions to allow assessment of response consistency. Claude responses to nine standardized questions on stuttering information, assessment, and therapy were generated in separate sessions and recorded for independent expert evaluation. Questions were repeated under comparable conditions to allow assessment of response consistency. Google Gemini responses to nine standardized questions on stuttering information, assessment, and therapy were generated in separate sessions and recorded for independent expert evaluation. Questions were repeated under comparable conditions to allow assessment of response consistency. Grok-4.20 responses to nine standardized questions on stuttering information, assessment, and therapy were generated in separate sessions and recorded for independent expert evaluation. Questions were repeated under comparable conditions to allow assessment of response consistency. |
Was misst die Studie?
Primäre Ergebnismessungen
Ergebnis Maßnahme |
Maßnahmenbeschreibung |
Zeitfenster |
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Expert-Rated Quality of Large Language Model Responses
Zeitfenster: During the single cross-sectional expert evaluation conducted over approximately 1 month
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Responses generated by four large language models (ChatGPT, Claude, Google Gemini, and Grok-4.20) to nine standardized questions about stuttering were independently evaluated by five speech-language therapists with clinical experience in stuttering. Each response was rated using a 5-point Likert scale (1 = strongly disagree to 5 = strongly agree) across five criteria: relevance, accuracy, clarity, completeness, and consistency. Responses were evaluated against guideline-based reference information derived from evidence-based clinical practice guidance. Higher scores indicate better response quality and closer alignment with clinical practice guidance. Mean scores were calculated for each large language model and each evaluation criterion. |
During the single cross-sectional expert evaluation conducted over approximately 1 month
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Mitarbeiter und Ermittler
Sponsor
Studienaufzeichnungsdaten
Haupttermine studieren
Studienbeginn (Tatsächlich)
Primärer Abschluss (Tatsächlich)
Studienabschluss (Tatsächlich)
Studienanmeldedaten
Zuerst eingereicht
Zuerst eingereicht, das die QC-Kriterien erfüllt hat
Zuerst gepostet (Tatsächlich)
Studienaufzeichnungsaktualisierungen
Letztes Update gepostet (Tatsächlich)
Letztes eingereichtes Update, das die QC-Kriterien erfüllt
Zuletzt verifiziert
Mehr Informationen
Begriffe im Zusammenhang mit dieser Studie
Zusätzliche relevante MeSH-Bedingungen
Andere Studien-ID-Nummern
- LLM-STUTTER-2026
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Studiert ein von der US-amerikanischen FDA reguliertes Arzneimittelprodukt
Studiert ein von der US-amerikanischen FDA reguliertes Geräteprodukt
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