Investigation of Radiofrequency Device for Treatment of Wrinkles and Rhytides

Inclusion Criteria:

• Male or female at least 21 years old,
• Apparently healthy,
• Informed consent signed by the subject.

Exclusion Criteria:

• Tobacco smokers,
• History of skin hypersensitivity,
• Current skin disorder or infection (e.g., herpes simplex),
• Prior cosmetic treatments to the face (e.g. Botox) or facial fillers (e.g. Restylane),
• Subjects with a pacemakers, internal defibrillators or electronically, magnetically, and mechanically activated implants,
• Subjects with implanted medical prostheses (such as clips, pins or plates) proximal to the treatment site,
• The current or recent use (within the past 12 months) of isotretinoin,
• Pregnancy or breast feeding,
• Insulin dependent diabetic subjects,
• Oxygen dependent subjects,
• Subjects with severe chronic illness, scleroderma, or lupus,
• Subjects with open sores or scars in the treatment region, or
• Subjects with ischemia in the treatment region.