Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City
2017년 8월 3일 업데이트: Olivier Michel, Brugmann University Hospital
The research question is "Are the different types of house in Ho Chi Minh city equally contributing to chronic respiratory diseases?".
According to this question, a cross-sectional and explorative study was set up to explore the differences in the environmental characteristics and prevalence of chronic respiratory diseases among common housing types in Ho Chi Minh city. Preliminary work was performed in 100 houses (20 houses per type, included tube houses, rental houses, rural houses, slum and apartment) from November 2013 to June 2015. It included measures by environmental devices, questionnaires and indoor activities diaries.
This study will aim to collect information about the prevalence of chronic respiratory diseases (CRDs) inside those house types to understand more about role of house types in developing CRDs.
The objective is:
- to evaluate the relationships between the type of house and lung function of inhabitants in each housing type.
- to evaluate the effects of environmental risk factors in each house type on prevalence of CRDs
연구 개요
연구 유형
중재적
등록 (실제)
1500
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
-
-
-
Ho Chi Minh City, 베트남, 7000
- Pham Ngoc Thach University of Medicine
-
-
참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
10년 (어린이, 성인, 고령자)
건강한 자원 봉사자를 받아들입니다
예
연구 대상 성별
모두
설명
Inclusion Criteria:
- Everybody
Exclusion Criteria:
- Not able to answer the questionnaire or give informed consent
- Have a contra-indication for lung function test (acute myocardial infarction less that 1 month ago, pain related to spirometry, dementia/confused)
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 상영
- 할당: 무작위화되지 않음
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
|
실험적: Tube houses
Tube Houses.
Group of 75-100 houses, with 4 inhabitants per house.
Expected number of participants: 300-400.
Predicted number of non-smoker chronic respiratory disease of 18-24.
|
Basic lung function test performed with a micro-spirometer, without broncho dilatator
|
|
실험적: Apartment
Apartments.
Group of 75-100 apartments, with 4 inhabitants per apartment.
Expected number of participants: 300-400.
Predicted number of non-smoker chronic respiratory disease of 18-24.
|
Basic lung function test performed with a micro-spirometer, without broncho dilatator
|
|
실험적: Rental Houses
Rental Houses.
Group of 150-200 rental houses, with 2 inhabitants per rental house.
Expected number of participants: 300-400.
Predicted number of non-smoker chronic respiratory disease of 18-24.
|
Basic lung function test performed with a micro-spirometer, without broncho dilatator
|
|
실험적: Rural houses
Rural Houses.
Group of 40-60 rural houses, with 5 inhabitant per rural house.
Expected number of participants: 200-300.
Predicted number of non-smoker chronic respiratory disease of 12-18.
|
Basic lung function test performed with a micro-spirometer, without broncho dilatator
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
FEV1/FVC
기간: 5 minutes
|
Basic lung function test, without broncho dilatation (micro-spirometer).
All lung function related outcomes are performed during the same test.
FEV1: forced expiratory volume in one second.
FVC: Forced vital capacity.
|
5 minutes
|
|
FVC
기간: 5 minutes
|
Basic lung function test, without broncho dilatation (micro-spirometer).
All lung function related outcomes are performed during the same test.FVC: Forced vital capacity.
|
5 minutes
|
|
VC
기간: 5 minutes
|
Basic lung function test, without broncho dilatation (micro-spirometer).
All lung function related outcomes performed during the same test.
VC: Vital capacity
|
5 minutes
|
|
FEF 25-75%
기간: 5 minutes
|
Basic lung function test, without broncho dilatation (micro-spirometer).All lung function related outcomes are performed during the same test.
FEF: Forced expiratory flow
|
5 minutes
|
|
Socio-demographic status
기간: around 10 minutes
|
Socio-demographic data, assessed by a home made questionnaire
|
around 10 minutes
|
|
Health status
기간: around 10 minutes
|
Health status (symptomatology) data, assessed by a home made questionnaire
|
around 10 minutes
|
|
Indoor air exposure time
기간: around 10 minutes
|
Indoor air exposure (time spent indoor within housing types, with associated air characteristics) data, assessed by a home made questionnaire
|
around 10 minutes
|
공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
일반 간행물
- Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, Coates A, van der Grinten CP, Gustafsson P, Hankinson J, Jensen R, Johnson DC, MacIntyre N, McKay R, Miller MR, Navajas D, Pedersen OF, Wanger J. Interpretative strategies for lung function tests. Eur Respir J. 2005 Nov;26(5):948-68. doi: 10.1183/09031936.05.00035205. No abstract available.
- Lung function testing: selection of reference values and interpretative strategies. American Thoracic Society. Am Rev Respir Dis. 1991 Nov;144(5):1202-18. doi: 10.1164/ajrccm/144.5.1202. No abstract available.
- Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl. 1993 Mar;16:5-40. No abstract available.
- Flohr C, Tuyen LN, Quinnell RJ, Lewis S, Minh TT, Campbell J, Simmons C, Telford G, Brown A, Hien TT, Farrar J, Williams H, Pritchard DI, Britton J. Reduced helminth burden increases allergen skin sensitization but not clinical allergy: a randomized, double-blind, placebo-controlled trial in Vietnam. Clin Exp Allergy. 2010 Jan;40(1):131-42. doi: 10.1111/j.1365-2222.2009.03346.x. Epub 2009 Sep 15.
- Dherani M, Pope D, Mascarenhas M, Smith KR, Weber M, Bruce N. Indoor air pollution from unprocessed solid fuel use and pneumonia risk in children aged under five years: a systematic review and meta-analysis. Bull World Health Organ. 2008 May;86(5):390-398C. doi: 10.2471/blt.07.044529.
- Ezzati M, Kammen DM. The health impacts of exposure to indoor air pollution from solid fuels in developing countries: knowledge, gaps, and data needs. Environ Health Perspect. 2002 Nov;110(11):1057-68. doi: 10.1289/ehp.021101057.
- Bruce N, Perez-Padilla R, Albalak R. Indoor air pollution in developing countries: a major environmental and public health challenge. Bull World Health Organ. 2000;78(9):1078-92.
- Stocks J, Quanjer PH. Reference values for residual volume, functional residual capacity and total lung capacity. ATS Workshop on Lung Volume Measurements. Official Statement of The European Respiratory Society. Eur Respir J. 1995 Mar;8(3):492-506. doi: 10.1183/09031936.95.08030492. No abstract available.
- American Thoracic Society. Single-breath carbon monoxide diffusing capacity (transfer factor). Recommendations for a standard technique--1995 update. Am J Respir Crit Care Med. 1995 Dec;152(6 Pt 1):2185-98. doi: 10.1164/ajrccm.152.6.8520796. No abstract available.
- Cotes JE, Chinn DJ, Quanjer PH, Roca J, Yernault JC. Standardization of the measurement of transfer factor (diffusing capacity). Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl. 1993 Mar;16:41-52. No abstract available.
- Wang X, Dockery DW, Wypij D, Fay ME, Ferris BG Jr. Pulmonary function between 6 and 18 years of age. Pediatr Pulmonol. 1993 Feb;15(2):75-88. doi: 10.1002/ppul.1950150204.
- Quanjer PH, Stocks J, Polgar G, Wise M, Karlberg J, Borsboom G. Compilation of reference values for lung function measurements in children. Eur Respir J Suppl. 1989 Mar;4:184S-261S. No abstract available.
- COPD-more than just tobacco smoke. Lancet. 2009 Aug 29;374(9691):663. doi: 10.1016/S0140-6736(09)61535-X. No abstract available.
- Bousquet J, Kiley J, Bateman ED, Viegi G, Cruz AA, Khaltaev N, Ait Khaled N, Baena-Cagnani CE, Barreto ML, Billo N, Canonica GW, Carlsen KH, Chavannes N, Chuchalin A, Drazen J, Fabbri LM, Gerbase MW, Humbert M, Joos G, Masjedi MR, Makino S, Rabe K, To T, Zhi L. Prioritised research agenda for prevention and control of chronic respiratory diseases. Eur Respir J. 2010 Nov;36(5):995-1001. doi: 10.1183/09031936.00012610. Epub 2010 Mar 11.
- Samet JM, Spengler JD. Indoor environments and health: moving into the 21st century. Am J Public Health. 2003 Sep;93(9):1489-93. doi: 10.2105/ajph.93.9.1489.
- Bardana EJ Jr. Indoor pollution and its impact on respiratory health. Ann Allergy Asthma Immunol. 2001 Dec;87(6 Suppl 3):33-40. doi: 10.1016/s1081-1206(10)62338-1.
- Smith KR. Indoor air pollution in developing countries: recommendations for research. Indoor Air. 2002 Sep;12(3):198-207. doi: 10.1034/j.1600-0668.2002.01137.x.
- Smith KR, Mehta S. The burden of disease from indoor air pollution in developing countries: comparison of estimates. Int J Hyg Environ Health. 2003 Aug;206(4-5):279-89. doi: 10.1078/1438-4639-00224.
- Smith KR, Samet JM, Romieu I, Bruce N. Indoor air pollution in developing countries and acute lower respiratory infections in children. Thorax. 2000 Jun;55(6):518-32. doi: 10.1136/thorax.55.6.518.
- Rojas-Bracho L, Suh HH, Koutrakis P. Relationships among personal, indoor, and outdoor fine and coarse particle concentrations for individuals with COPD. J Expo Anal Environ Epidemiol. 2000 May-Jun;10(3):294-306. doi: 10.1038/sj.jea.7500092.
- Sarnat JA, Koutrakis P, Suh HH. Assessing the relationship between personal particulate and gaseous exposures of senior citizens living in Baltimore, MD. J Air Waste Manag Assoc. 2000 Jul;50(7):1184-98. doi: 10.1080/10473289.2000.10464165.
- Jaakkola MS. Environmental tobacco smoke and health in the elderly. Eur Respir J. 2002 Jan;19(1):172-81. doi: 10.1183/09031936.02.00270702.
- Smith KR. National burden of disease in India from indoor air pollution. Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13286-93. doi: 10.1073/pnas.97.24.13286.
- Briggs D. Environmental pollution and the global burden of disease. Br Med Bull. 2003;68:1-24. doi: 10.1093/bmb/ldg019.
- Raw GJ, Coward SK, Brown VM, Crump DR. Exposure to air pollutants in English homes. J Expo Anal Environ Epidemiol. 2004;14 Suppl 1:S85-94. doi: 10.1038/sj.jea.7500363.
- Viegi G, Simoni M, Scognamiglio A, Baldacci S, Pistelli F, Carrozzi L, Annesi-Maesano I. Indoor air pollution and airway disease. Int J Tuberc Lung Dis. 2004 Dec;8(12):1401-15.
- Levesqu B, Allaire S, Gauvin D, Koutrakis P, Gingras S, Rhainds M, Prud'Homme H, Duchesne JF. Wood-burning appliances and indoor air quality. Sci Total Environ. 2001 Dec 17;281(1-3):47-62. doi: 10.1016/s0048-9697(01)00834-8.
- Naeher LP, Smith KR, Leaderer BP, Neufeld L, Mage DT. Carbon monoxide as a tracer for assessing exposures to particulate matter in wood and gas cookstove households of highland Guatemala. Environ Sci Technol. 2001 Feb 1;35(3):575-81. doi: 10.1021/es991225g.
- Rollin HB, Mathee A, Bruce N, Levin J, von Schirnding YE. Comparison of indoor air quality in electrified and un-electrified dwellings in rural South African villages. Indoor Air. 2004 Jun;14(3):208-16. doi: 10.1111/j.1600-0668.2004.00238.x.
- Schwela D. Cooking smoke: a silent killer. People Planet. 1997;6(3):24-5.
- Wolkoff P, Schneider T, Kildeso J, Degerth R, Jaroszewski M, Schunk H. Risk in cleaning: chemical and physical exposure. Sci Total Environ. 1998 Apr 23;215(1-2):135-56. doi: 10.1016/s0048-9697(98)00110-7.
- Delfino RJ. Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research. Environ Health Perspect. 2002 Aug;110 Suppl 4(Suppl 4):573-89. doi: 10.1289/ehp.02110s4573.
- Payne-Sturges DC, Burke TA, Breysse P, Diener-West M, Buckley TJ. Personal exposure meets risk assessment: a comparison of measured and modeled exposures and risks in an urban community. Environ Health Perspect. 2004 Apr;112(5):589-98. doi: 10.1289/ehp.6496.
- Regional COPD Working Group. COPD prevalence in 12 Asia-Pacific countries and regions: projections based on the COPD prevalence estimation model. Respirology. 2003 Jun;8(2):192-8. doi: 10.1046/j.1440-1843.2003.00460.x.
- Tan WC, Ng TP. COPD in Asia: where East meets West. Chest. 2008 Feb;133(2):517-27. doi: 10.1378/chest.07-1131.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작
2016년 9월 1일
기본 완료 (실제)
2017년 7월 1일
연구 완료 (실제)
2017년 7월 1일
연구 등록 날짜
최초 제출
2016년 9월 8일
QC 기준을 충족하는 최초 제출
2016년 9월 8일
처음 게시됨 (추정)
2016년 9월 13일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2017년 8월 4일
QC 기준을 충족하는 마지막 업데이트 제출
2017년 8월 3일
마지막으로 확인됨
2017년 8월 1일
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .
만성 호흡기 질환에 대한 임상 시험
-
Hospital Clinic of BarcelonaAstraZeneca완전한CTO(Chronic Total Occlusion)를 위한 PCI(Percutaneous Coronary Intervention)를 받을 예정인 환자스페인
-
University of Pennsylvania완전한Intrntl Classification of Diseases, 9th Revision, (ICD-9-CM) 410의 주진단 또는 이차진단 코드가 있는 환자(5번째 숫자가 2인 경우 제외)미국
설문지에 대한 임상 시험
-
University Hospital, Toulouse완전한
-
Assistance Publique - Hôpitaux de Paris완전한
-
T.C. ORDU ÜNİVERSİTESİMacquarie University, Australia모집하지 않고 적극적으로
-
Centre Hospitalier Emile RouxUniversité Clermont-Auvergne, France아직 모집하지 않음
-
Cambridge University Hospitals NHS Foundation TrustUniversity of Cambridge알려지지 않은근골격계 질환 | 근골격계 부상
-
University Hospital, Rouen아직 모집하지 않음
-
Medical University of Lublin완전한
-
Istanbul Kültür UniversityMarmara University; Istanbul University - Cerrahpasa (IUC)완전한