Comparison of Outcomes of Plantar vs Groin Full-Thickness Skin Graft for Correction of Congenital Syndactyly of Hand
Congenital syndactyly is a condition present at birth in which two or more fingers are joined together. Surgical correction was performed to separate the fingers, improve hand appearance, and support better hand function. After separation of the fingers, a skin graft is often needed to cover the skin defect created during surgery. Full-thickness skin grafts may be taken from different donor sites. The groin has commonly been used as a donor site, but groin skin may differ from hand skin in color and texture. The plantar area of the foot has been considered as an alternative donor site because it may provide better color and texture matching and the donor scar is usually less visible.
This randomized controlled study compared the outcomes of plantar full-thickness skin grafts with groin full-thickness skin grafts in children who underwent surgical correction for congenital simple complete syndactyly of the hand. The study was conducted in the Department of Plastic Surgery, Sheikh Zayed Hospital, Rahim Yar Khan. Children aged 1 to 10 years with congenital simple complete syndactyly who required surgical correction with skin grafting were enrolled after written informed consent was obtained from their guardians. Children with complex syndactyly, associated congenital syndromes, infections, skin diseases, previous surgery on the affected hand, or missing postoperative photographs were not included.
The participants were assigned to one of two treatment groups by sealed opaque envelopes using a lottery method. One group received a plantar full-thickness skin graft, while the other group received a groin full-thickness skin graft. All operations were performed by a consultant plastic surgeon according to standard surgical practice. Postoperative follow-up was carried out at 2 weeks, 4 weeks, and 6 weeks after surgery.
The main purpose of the study was to compare postoperative complications between the two graft methods. These complications included scar contracture, web creep, donor-site hypertrophic scarring, and delayed healing. Scar contracture referred to tightening or shrinking of the graft or surrounding tissues that could limit finger movement or cause deformity. Web creep referred to distal migration of the reconstructed web space after surgery. Donor-site complications included raised or thickened scarring and delayed wound healing. These outcomes were assessed during follow-up visits by a consultant plastic surgeon who was blinded to the treatment group.
Studie Overzicht
Toestand
Conditie
Interventie / Behandeling
Studietype
Inschrijving (Werkelijk)
Fase
- Niet toepasbaar
Contacten en locaties
Studie Locaties
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Punjab Province
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Rahim Yar Khan, Punjab Province, Pakistan, 64200
- Sheikh Zayed Medical College/Hospital
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Deelname Criteria
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
- Kind
Accepteert gezonde vrijwilligers
Beschrijving
Inclusion Criteria:
- Patients aged 1 to 10 years of either gender with congenital simple complete syndactyly
- Cases requiring surgical correction with skin grafting.
- Patients with no prior surgical intervention on the affected hand.
Exclusion Criteria:
- Patients with complex syndactyly or other systemic conditions, including congenital syndromes, infections and skin diseases
- Patients with missing postoperative photographs.
Studie plan
Hoe is de studie opgezet?
Ontwerpdetails
- Primair doel: Behandeling
- Toewijzing: Gerandomiseerd
- Interventioneel model: Parallelle opdracht
- Masker: Geen (open label)
Wapens en interventies
Deelnemersgroep / Arm |
Interventie / Behandeling |
|---|---|
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Experimenteel: Group I - Plantar Full-Thickness Skin Graft
Participants assigned to this group received surgical correction of congenital simple complete syndactyly of the hand using a plantar full-thickness skin graft.
The graft was harvested from the plantar surface of the foot and used to cover the skin defect created after syndactyly release.
Participants were followed postoperatively at 2 weeks, 4 weeks, and 6 weeks for assessment of healing, scar contracture, web creep, donor-site complications, guardian satisfaction, and aesthetic outcome.
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Syndactyly release was performed under standard surgical protocol.
A full-thickness skin graft was harvested from the plantar surface of the foot and applied to the recipient defect after separation of the fused fingers.
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Actieve vergelijker: Group II - Groin Full-Thickness Skin Graft
Participants assigned to this group received surgical correction of congenital simple complete syndactyly of the hand using a groin full-thickness skin graft.
The graft was harvested from the groin region and used to cover the skin defect created after syndactyly release.
Participants were followed postoperatively at 2 weeks, 4 weeks, and 6 weeks for assessment of healing, scar contracture, web creep, donor-site complications, guardian satisfaction, and aesthetic outcome.
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Syndactyly release was performed under standard surgical protocol.
A full-thickness skin graft was harvested from the groin region and applied to the recipient defect after separation of the fused fingers.
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Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
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Frequency of Scar Contracture
Tijdsspanne: 2 weeks, 4 weeks, and 6 weeks after surgery
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Scar contracture was assessed as abnormal tightening or shrinkage of the graft or surrounding tissue after syndactyly correction, resulting in visible tightness, deformity, or limitation of finger movement at the surgical site.
It was graded as none, mild, moderate, or severe according to clinical examination of range of motion and visible contracture.
Assessment was performed by a consultant plastic surgeon blinded to the treatment group.
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2 weeks, 4 weeks, and 6 weeks after surgery
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Frequency of Web Creep
Tijdsspanne: 2 weeks, 4 weeks, and 6 weeks after surgery
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Web creep was assessed as distal migration of the reconstructed web space beyond the expected anatomical location after syndactyly correction.
It was evaluated by visual inspection and measurement from the metacarpophalangeal joint crease to the web apex.
Web creep was categorized as absent, less than 5 mm, 5 to 10 mm, or more than 10 mm.
Assessment was performed by a consultant plastic surgeon blinded to the treatment group.
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2 weeks, 4 weeks, and 6 weeks after surgery
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Frequency of Donor-Site Hypertrophic Scarring
Tijdsspanne: 2 weeks, 4 weeks, and 6 weeks after surgery
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Donor-site hypertrophic scarring was assessed as a raised, thickened, erythematous, or pruritic scar confined within the boundaries of the original donor-site wound.
It was evaluated through visual and tactile examination of the donor site.
The outcome was recorded as present or absent.
Assessment was performed by a consultant plastic surgeon blinded to the treatment group.
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2 weeks, 4 weeks, and 6 weeks after surgery
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Frequency of Delayed Healing
Tijdsspanne: 2 weeks, 4 weeks, and 6 weeks after surgery
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Delayed healing was assessed as failure of complete epithelialization of the graft or donor-site wound within more than 3 weeks after surgery, or the presence of wound dehiscence, infection, necrosis, or persistent exudate.
The outcome was recorded according to clinical wound examination.
Assessment was performed by a consultant plastic surgeon blinded to the treatment group.
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2 weeks, 4 weeks, and 6 weeks after surgery
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Secundaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
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Aesthetic Outcome Score
Tijdsspanne: 6 weeks after surgery
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The aesthetic outcome of the operated hand was assessed using a 1 to 10 score by a consultant plastic surgeon blinded to the treatment group.
The score was based on cosmetic appearance, including scar quality, web space appearance, symmetry, and overall visual restoration of the hand.
Lower scores indicated poor aesthetic outcome, while higher scores indicated excellent cosmetic outcome.
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6 weeks after surgery
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Healing Time
Tijdsspanne: Up to 6 weeks after surgery
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Healing time was recorded as the total number of days required for complete epithelialization of the graft and donor-site wounds after surgery.
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Up to 6 weeks after surgery
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Guardian Satisfaction Score
Tijdsspanne: 6 weeks after surgery
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Guardian satisfaction with the surgical outcome was recorded using a visual analogue scale ranging from 1 to 10. Lower scores indicated poor satisfaction, while higher scores indicated greater satisfaction with the overall surgical outcome, including appearance, function, and healing of the operated hand.
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6 weeks after surgery
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Medewerkers en onderzoekers
Sponsor
Onderzoekers
- Hoofdonderzoeker: Wardah Rehmat, Sheikh Zayed Medical college/Hospital, Rahimyar Khan
Studie record data
Bestudeer belangrijke data
Studie start (Werkelijk)
Primaire voltooiing (Werkelijk)
Studie voltooiing (Werkelijk)
Studieregistratiedata
Eerst ingediend
Eerst ingediend dat voldeed aan de QC-criteria
Eerst geplaatst (Werkelijk)
Updates van studierecords
Laatste update geplaatst (Werkelijk)
Laatste update ingediend die voldeed aan QC-criteria
Laatst geverifieerd
Meer informatie
Termen gerelateerd aan deze studie
Trefwoorden
Andere studie-ID-nummers
- Sheikh ZMC/H6
Informatie over medicijnen en apparaten, studiedocumenten
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