S1216, fase III ADT+TAK-700 vs. ADT+Bicalutamid for metastatisk prostatakreft (S1216)
10. desember 2025 oppdatert av: SWOG Cancer Research Network
En fase III randomisert studie som sammenligner androgen deprivasjonsterapi + TAK-700 med androgen deprivasjonsterapi + bikalutamid hos pasienter med nylig diagnostisert metastatisk sensitiv prostatakreft
Hensikten med denne studien er å sammenligne total overlevelse hos nylig diagnostiserte metastaserende prostatakreftpasienter tilfeldig tildelt androgen deprivasjonsterapi (ADT) + TAK-700 versus ADT + bicalutamid.
Studieoversikt
Status
Fullført
Forhold
Intervensjon / Behandling
Studietype
Intervensjonell
Registrering (Faktiske)
1313
Fase
- Fase 3
Kontakter og plasseringer
Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.
Studiesteder
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Alabama
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Birmingham, Alabama, Forente stater, 35233
- Veterans Administration Medical Center - Birmingham
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Arizona
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Phoenix, Arizona, Forente stater, 85004
- University of Arizona Cancer Center at Saint Joseph's
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Tucson, Arizona, Forente stater, 85704
- University of Arizona Cancer Center-Orange Grove Campus
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Tucson, Arizona, Forente stater, 85719
- University of Arizona Cancer Center-North Campus
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Tucson, Arizona, Forente stater, 85724
- The University of Arizona Medical Center-University Campus
-
Tucson, Arizona, Forente stater, 85723
- Southern Arizona Veterans Affairs Health Center
-
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Arkansas
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Jonesboro, Arkansas, Forente stater, 72401
- Fowler Family Center for Cancer Care
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Little Rock, Arkansas, Forente stater, 72205
- Veteran's Administration Medical Center
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California
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Antioch, California, Forente stater, 94531
- Kaiser Permanente-Deer Valley Medical Center
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Auburn, California, Forente stater, 95602
- Sutter Auburn Faith Hospital
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Bakersfield, California, Forente stater, 93301
- AIS Cancer Center at San Joaquin Community Hospital
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Berkeley, California, Forente stater, 94704
- Alta Bates Summit Medical Center-Herrick Campus
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Burlingame, California, Forente stater, 94010
- Mills - Peninsula Hospitals
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Corona, California, Forente stater, 92879
- City of Hope Corona
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Davis, California, Forente stater, 95616
- Sutter Davis Hospital
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Duarte, California, Forente stater, 91010
- City of Hope Comprehensive Cancer Center
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Fremont, California, Forente stater, 94538
- Kaiser Permanente-Fremont
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Fresno, California, Forente stater, 93720
- Kaiser Permanente
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Fresno, California, Forente stater, 93701
- University Oncology Associates
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La Jolla, California, Forente stater, 92093
- UC San Diego Moores Cancer Center
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Loma Linda, California, Forente stater, 92354
- Loma Linda University Medical Center
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Loma Linda, California, Forente stater, 92357
- Veterans Affairs Loma Linda Healthcare System
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Los Angeles, California, Forente stater, 90033
- USC / Norris Comprehensive Cancer Center
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Los Angeles, California, Forente stater, 90033
- Los Angeles County-USC Medical Center
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Marysville, California, Forente stater, 95901
- Fremont - Rideout Cancer Center
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Mather, California, Forente stater, 95655
- Mather Veteran Affairs Medical Center
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Merced, California, Forente stater, 95340
- Mercy UC Davis Cancer Center
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Modesto, California, Forente stater, 95355
- Memorial Medical Center
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Modesto, California, Forente stater, 95356
- Kaiser Permanente-Modesto
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Mountain View, California, Forente stater, 94040
- Palo Alto Medical Foundation-Camino Division
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Mountain View, California, Forente stater, 94040
- Palo Alto Medical Foundation-Gynecologic Oncology
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Newport Beach, California, Forente stater, 92663
- USC Norris Oncology/Hematology-Newport Beach
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Novato, California, Forente stater, 94945
- Sutter Cancer Research Consortium
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Oakland, California, Forente stater, 94611
- Kaiser Permanente-Oakland
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Orange, California, Forente stater, 92868
- UC Irvine Health/Chao Family Comprehensive Cancer Center
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Palo Alto, California, Forente stater, 94301
- Palo Alto Medical Foundation Health Care
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Pasadena, California, Forente stater, 91105
- Keck Medical Center of USC Pasadena
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Pismo Beach, California, Forente stater, 93449
- PCR Oncology
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Redwood City, California, Forente stater, 94063
- Kaiser Permanente-Redwood City
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Richmond, California, Forente stater, 94801
- Kaiser Permanente-Richmond
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Roseville, California, Forente stater, 95661
- Kaiser Permanente-Roseville
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Roseville, California, Forente stater, 95661
- Sutter Roseville Medical Center
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Sacramento, California, Forente stater, 95817
- University of California Davis Comprehensive Cancer Center
-
Sacramento, California, Forente stater, 95823
- Kaiser Permanente-South Sacramento
-
Sacramento, California, Forente stater, 95825
- Kaiser Permanente - Sacramento
-
Sacramento, California, Forente stater, 95816
- Sutter General Hospital
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San Francisco, California, Forente stater, 94115
- Kaiser Permanente-San Francisco
-
San Francisco, California, Forente stater, 94158
- UCSF Medical Center-Mission Bay
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San Francisco, California, Forente stater, 94115
- California Pacific Medical Center-Pacific Campus
-
San Francisco, California, Forente stater, 94115
- UCSF Medical Center-Mount Zion
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San Jose, California, Forente stater, 95119
- Kaiser Permanente-Santa Teresa-San Jose
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San Leandro, California, Forente stater, 94577
- Kaiser Permanente San Leandro
-
San Rafael, California, Forente stater, 94903
- Kaiser Permanente-San Rafael
-
Santa Clara, California, Forente stater, 95051
- Kaiser Permanente Medical Center - Santa Clara
-
Santa Cruz, California, Forente stater, 95065
- Palo Alto Medical Foundation-Santa Cruz
-
Santa Rosa, California, Forente stater, 95403
- Kaiser Permanente-Santa Rosa
-
Santa Rosa, California, Forente stater, 95403
- Sutter Pacific Medical Foundation
-
South San Francisco, California, Forente stater, 94080
- Kaiser Permanente-South San Francisco
-
Stockton, California, Forente stater, 95210
- Kaiser Permanente-Stockton
-
Sunnyvale, California, Forente stater, 94086
- Palo Alto Medical Foundation-Sunnyvale
-
Truckee, California, Forente stater, 96161
- Gene Upshaw Memorial Tahoe Forest Cancer Center
-
Vacaville, California, Forente stater, 95688
- Kaiser Permanente Medical Center-Vacaville
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Vacaville, California, Forente stater, 95687
- Northbay Cancer Center
-
Vallejo, California, Forente stater, 94589
- Kaiser Permanente-Vallejo
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Vallejo, California, Forente stater, 94589
- Sutter Solano Medical Center/Cancer Center
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Walnut Creek, California, Forente stater, 94596
- Kaiser Permanente-Walnut Creek
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Colorado
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Aurora, Colorado, Forente stater, 80045
- University of Colorado Cancer Center - Anschutz Cancer Pavilion
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Aurora, Colorado, Forente stater, 80012
- Rocky Mountain Cancer Centers-Aurora
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Aurora, Colorado, Forente stater, 80012
- The Medical Center of Aurora
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Boulder, Colorado, Forente stater, 80301
- Boulder Community Hospital
-
Boulder, Colorado, Forente stater, 80304
- Rocky Mountain Cancer Centers-Boulder
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Colorado Springs, Colorado, Forente stater, 80907
- Penrose-Saint Francis Healthcare
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Colorado Springs, Colorado, Forente stater, 80907
- Rocky Mountain Cancer Centers-Penrose
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Denver, Colorado, Forente stater, 80210
- Porter Adventist Hospital
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Denver, Colorado, Forente stater, 80218
- Presbyterian - Saint Lukes Medical Center - Health One
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Denver, Colorado, Forente stater, 80218
- SCL Health Saint Joseph Hospital
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Denver, Colorado, Forente stater, 80220
- Rose Medical Center
-
Denver, Colorado, Forente stater, 80218
- Rocky Mountain Cancer Centers-Midtown
-
Denver, Colorado, Forente stater, 80220
- Rocky Mountain Cancer Centers-Rose
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Denver, Colorado, Forente stater, 80218
- Colorado Blood Cancer Institute
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Denver, Colorado, Forente stater, 80222
- Colorado Cancer Research Program NCORP
-
Durango, Colorado, Forente stater, 81301
- Mercy Medical Center
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Durango, Colorado, Forente stater, 81301
- Southwest Oncology PC
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Englewood, Colorado, Forente stater, 80113
- Swedish Medical Center
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Englewood, Colorado, Forente stater, 80113
- Comprehensive Cancer Care and Research Institute of Colorado LLC
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Golden, Colorado, Forente stater, 80401
- Mountain Blue Cancer Care Center
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Greeley, Colorado, Forente stater, 80631
- North Colorado Medical Center
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Greenwood Village, Colorado, Forente stater, 80111
- Rocky Mountain Cancer Centers-Greenwood Village
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Lakewood, Colorado, Forente stater, 80228
- Saint Anthony Hospital
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Lakewood, Colorado, Forente stater, 80228
- Rocky Mountain Cancer Centers-Lakewood
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Littleton, Colorado, Forente stater, 80120
- Rocky Mountain Cancer Centers-Littleton
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Littleton, Colorado, Forente stater, 80122
- Littleton Adventist Hospital
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Lone Tree, Colorado, Forente stater, 80124
- Sky Ridge Medical Center
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Lone Tree, Colorado, Forente stater, 80124
- Rocky Mountain Cancer Centers-Sky Ridge
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Longmont, Colorado, Forente stater, 80501
- Longmont United Hospital
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Longmont, Colorado, Forente stater, 80501
- Rocky Mountain Cancer Centers-Longmont
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Loveland, Colorado, Forente stater, 80539
- McKee Medical Center
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Parker, Colorado, Forente stater, 80138
- Parker Adventist Hospital
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Parker, Colorado, Forente stater, 80138
- Rocky Mountain Cancer Centers-Parker
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Pueblo, Colorado, Forente stater, 81004
- Saint Mary Corwin Medical Center
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Pueblo, Colorado, Forente stater, 81008
- Rocky Mountain Cancer Centers - Pueblo
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Thornton, Colorado, Forente stater, 80260
- Rocky Mountain Cancer Centers-Thornton
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Wheat Ridge, Colorado, Forente stater, 80033
- SCL Health Lutheran Medical Center
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Connecticut
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Greenwich, Connecticut, Forente stater, 06830
- Greenwich Hospital
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New Haven, Connecticut, Forente stater, 06520
- Yale University
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Norwich, Connecticut, Forente stater, 06360
- Eastern Connecticut Hematology and Oncology Associates
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Stamford, Connecticut, Forente stater, 06904
- Stamford Hospital/Bennett Cancer Center
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Delaware
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Lewes, Delaware, Forente stater, 19958
- Beebe Medical Center
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Newark, Delaware, Forente stater, 19713
- Medical Oncology Hematology Consultants PA
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Newark, Delaware, Forente stater, 19718
- Christiana Care Health System-Christiana Hospital
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Newark, Delaware, Forente stater, 19713
- Regional Hematology and Oncology PA
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Seaford, Delaware, Forente stater, 19973
- Nanticoke Memorial Hospital
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District of Columbia
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Washington D.C., District of Columbia, Forente stater, 20037
- George Washington University Medical Center
-
Washington D.C., District of Columbia, Forente stater, 20010
- MedStar Washington Hospital Center
-
Washington D.C., District of Columbia, Forente stater, 20007
- MedStar Georgetown University Hospital
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Washington D.C., District of Columbia, Forente stater, 20016
- Sibley Memorial Hospital
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Washington D.C., District of Columbia, Forente stater, 20422
- Veterans Affairs Medical Center -Washington DC
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Florida
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Fort Lauderdale, Florida, Forente stater, 33316
- Broward Health Medical Center
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Lakeland, Florida, Forente stater, 33805
- Lakeland Regional Health Hollis Cancer Center
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Orlando, Florida, Forente stater, 32803
- Florida Hospital Orlando
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Orlando, Florida, Forente stater, 32806
- UF Cancer Center at Orlando Health
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Tampa, Florida, Forente stater, 33612
- Moffitt Cancer Center
-
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Georgia
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Columbus, Georgia, Forente stater, 31904
- John B Amos Cancer Center
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Decatur, Georgia, Forente stater, 30033
- Atlanta VA Medical Center
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Gainesville, Georgia, Forente stater, 30501
- Northeast Georgia Medical Center-Gainesville
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Savannah, Georgia, Forente stater, 31405
- Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
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Hawaii
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Honolulu, Hawaii, Forente stater, 96813
- Queen's Medical Center
-
Honolulu, Hawaii, Forente stater, 96813
- University of Hawaii Cancer Center
-
Honolulu, Hawaii, Forente stater, 96817
- Hawaii Cancer Care Inc-Liliha
-
Honolulu, Hawaii, Forente stater, 96819
- Kaiser Permanente Moanalua Medical Center
-
Honolulu, Hawaii, Forente stater, 96813
- Hawaii Cancer Care Inc-POB II
-
Honolulu, Hawaii, Forente stater, 96817
- Hawaii Oncology Inc-Kuakini
-
Honolulu, Hawaii, Forente stater, 96859
- Tripler Army Medical Center
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‘Aiea, Hawaii, Forente stater, 96701
- Hawaii Oncology Inc-Pali Momi
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Idaho
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Boise, Idaho, Forente stater, 83706
- Saint Alphonsus Cancer Care Center-Boise
-
Coeur d'Alene, Idaho, Forente stater, 83814
- Kootenai Medical Center
-
Post Falls, Idaho, Forente stater, 83854
- Kootenai Cancer Center
-
Sandpoint, Idaho, Forente stater, 83864
- Kootenai Cancer Clinic
-
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Illinois
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Aurora, Illinois, Forente stater, 60504
- Rush - Copley Medical Center
-
Bloomington, Illinois, Forente stater, 61704
- Illinois CancerCare-Bloomington
-
Bloomington, Illinois, Forente stater, 61701
- Saint Joseph Medical Center
-
Canton, Illinois, Forente stater, 61520
- Illinois CancerCare-Canton
-
Carthage, Illinois, Forente stater, 62321
- Illinois CancerCare-Carthage
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Centralia, Illinois, Forente stater, 62801
- Centralia Oncology Clinic
-
Chicago, Illinois, Forente stater, 60611
- Northwestern University
-
Chicago, Illinois, Forente stater, 60637
- University of Chicago Comprehensive Cancer Center
-
Chicago, Illinois, Forente stater, 60608
- Mount Sinai Hospital Medical Center
-
Chicago, Illinois, Forente stater, 60640
- Weiss Memorial Hospital
-
Chicago, Illinois, Forente stater, 60657
- Presence Saint Joseph Hospital-Chicago
-
Decatur, Illinois, Forente stater, 62526
- Decatur Memorial Hospital
-
Decatur, Illinois, Forente stater, 62526
- Heartland Cancer Research NCORP
-
Decatur, Illinois, Forente stater, 62526
- Cancer Care Center of Decatur
-
Effingham, Illinois, Forente stater, 62401
- Crossroads Cancer Center
-
Eureka, Illinois, Forente stater, 61530
- Illinois CancerCare-Eureka
-
Evanston, Illinois, Forente stater, 60201
- NorthShore University HealthSystem-Evanston Hospital
-
Galesburg, Illinois, Forente stater, 61401
- Illinois CancerCare-Galesburg
-
Geneva, Illinois, Forente stater, 60134
- Northwestern Medicine Cancer Center Delnor
-
Glenview, Illinois, Forente stater, 60026
- NorthShore University HealthSystem-Glenbrook Hospital
-
Highland Park, Illinois, Forente stater, 60035
- NorthShore University HealthSystem-Highland Park Hospital
-
Hines, Illinois, Forente stater, 60141
- Hines Veterans Administration Hospital
-
Joliet, Illinois, Forente stater, 60435
- Joliet Oncology-Hematology Associates Limited
-
Kankakee, Illinois, Forente stater, 60901
- Presence Saint Mary's Hospital
-
Kewanee, Illinois, Forente stater, 61443
- Illinois CancerCare-Kewanee Clinic
-
Macomb, Illinois, Forente stater, 61455
- Illinois CancerCare-Macomb
-
Maywood, Illinois, Forente stater, 60153
- Loyola University Medical Center
-
Moline, Illinois, Forente stater, 61265
- Trinity Medical Center
-
Monmouth, Illinois, Forente stater, 61462
- Illinois CancerCare-Monmouth
-
Normal, Illinois, Forente stater, 61761
- Community Cancer Center Foundation
-
Ottawa, Illinois, Forente stater, 61350
- Illinois CancerCare-Ottawa Clinic
-
Ottawa, Illinois, Forente stater, 61350
- Ottawa Regional Hospital and Healthcare Center
-
Pekin, Illinois, Forente stater, 61554
- Illinois CancerCare-Pekin
-
Pekin, Illinois, Forente stater, 61554
- OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
-
Peoria, Illinois, Forente stater, 61637
- OSF Saint Francis Medical Center
-
Peoria, Illinois, Forente stater, 61615
- Illinois CancerCare-Peoria
-
Peoria, Illinois, Forente stater, 61614
- Proctor Hospital
-
Peoria, Illinois, Forente stater, 61603
- Methodist Medical Center of Illinois
-
Peru, Illinois, Forente stater, 61354
- Illinois CancerCare-Peru
-
Princeton, Illinois, Forente stater, 61356
- Illinois CancerCare-Princeton
-
River Forest, Illinois, Forente stater, 60305
- West Suburban Medical Center
-
Rockford, Illinois, Forente stater, 61114
- SwedishAmerican Regional Cancer Center/ACT
-
Springfield, Illinois, Forente stater, 62781
- Memorial Medical Center
-
Springfield, Illinois, Forente stater, 62702
- Southern Illinois University School of Medicine
-
Springfield, Illinois, Forente stater, 62702
- Springfield Clinic
-
Swansea, Illinois, Forente stater, 62226
- Cancer Care Specialists of Illinois-Swansea
-
Urbana, Illinois, Forente stater, 61801
- Carle Cancer Center
-
Warrenville, Illinois, Forente stater, 60555
- Northwestern Medicine Cancer Center Warrenville
-
Yorkville, Illinois, Forente stater, 60560
- Rush-Copley Healthcare Center
-
-
Indiana
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Bloomington, Indiana, Forente stater, 47403
- IU Health Bloomington
-
Mishawaka, Indiana, Forente stater, 46545
- Memorial Regional Cancer Center Day Road
-
South Bend, Indiana, Forente stater, 46601
- Memorial Hospital of South Bend
-
Valparaiso, Indiana, Forente stater, 46383
- Porter Memorial Hospital
-
-
Iowa
-
Ames, Iowa, Forente stater, 50010
- McFarland Clinic PC-William R Bliss Cancer Center
-
Cedar Rapids, Iowa, Forente stater, 52403
- Mercy Hospital
-
Cedar Rapids, Iowa, Forente stater, 52403
- Oncology Associates at Mercy Medical Center
-
Clive, Iowa, Forente stater, 50325
- Medical Oncology and Hematology Associates-West Des Moines
-
Council Bluffs, Iowa, Forente stater, 51503
- Alegent Health Mercy Hospital
-
Davenport, Iowa, Forente stater, 52803
- Genesis Medical Center - East Campus
-
Des Moines, Iowa, Forente stater, 50314
- Mercy Medical Center - Des Moines
-
Des Moines, Iowa, Forente stater, 50314
- Medical Oncology and Hematology Associates-Laurel
-
Iowa City, Iowa, Forente stater, 52242
- University of Iowa/Holden Comprehensive Cancer Center
-
Iowa City, Iowa, Forente stater, 52246
- Iowa City VA Healthcare System
-
-
Kansas
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Chanute, Kansas, Forente stater, 66720
- Cancer Center of Kansas - Chanute
-
Dodge City, Kansas, Forente stater, 67801
- Cancer Center of Kansas - Dodge City
-
El Dorado, Kansas, Forente stater, 67042
- Cancer Center of Kansas - El Dorado
-
Fort Scott, Kansas, Forente stater, 66701
- Cancer Center of Kansas - Fort Scott
-
Garden City, Kansas, Forente stater, 67846
- Saint Catherine Hospital
-
Great Bend, Kansas, Forente stater, 67530
- Saint Rose Ambulatory and Surgery Center
-
Great Bend, Kansas, Forente stater, 67530
- Heartland Cancer Center
-
Hays, Kansas, Forente stater, 67601
- Hays Medical Center
-
Independence, Kansas, Forente stater, 67301
- Cancer Center of Kansas-Independence
-
Kansas City, Kansas, Forente stater, 66160
- University of Kansas Cancer Center
-
Kansas City, Kansas, Forente stater, 66112
- University of Kansas Cancer Center-West
-
Kingman, Kansas, Forente stater, 67068
- Cancer Center of Kansas-Kingman
-
Lawrence, Kansas, Forente stater, 66044
- Lawrence Memorial Hospital
-
Liberal, Kansas, Forente stater, 67905
- Cancer Center of Kansas-Liberal
-
Manhattan, Kansas, Forente stater, 66502
- Cancer Center of Kansas-Manhattan
-
McPherson, Kansas, Forente stater, 67460
- Cancer Center of Kansas - McPherson
-
Newton, Kansas, Forente stater, 67114
- Cancer Center of Kansas - Newton
-
Olathe, Kansas, Forente stater, 66061
- Olathe Medical Center
-
Overland Park, Kansas, Forente stater, 66210
- University of Kansas Cancer Center-Overland Park
-
Overland Park, Kansas, Forente stater, 66209
- Menorah Medical Center
-
Parsons, Kansas, Forente stater, 67357
- Cancer Center of Kansas - Parsons
-
Pratt, Kansas, Forente stater, 67124
- Cancer Center of Kansas - Pratt
-
Salina, Kansas, Forente stater, 67401
- Salina Regional Health Center
-
Salina, Kansas, Forente stater, 67401
- Cancer Center of Kansas - Salina
-
Topeka, Kansas, Forente stater, 66606
- Cotton O'Neil Cancer Center / Stormont Vail Health
-
Topeka, Kansas, Forente stater, 66606
- Saint Francis Hospital and Medical Center - Topeka
-
Topeka, Kansas, Forente stater, 66622
- Topeka VA Hospital
-
Wellington, Kansas, Forente stater, 67152
- Cancer Center of Kansas - Wellington
-
Wichita, Kansas, Forente stater, 67208
- Cancer Center of Kansas-Wichita Medical Arts Tower
-
Wichita, Kansas, Forente stater, 67214
- Cancer Center of Kansas - Wichita
-
Wichita, Kansas, Forente stater, 67208
- Associates In Womens Health
-
Wichita, Kansas, Forente stater, 67214
- Wichita NCI Community Oncology Research Program
-
Wichita, Kansas, Forente stater, 67214
- Via Christi Regional Medical Center
-
Winfield, Kansas, Forente stater, 67156
- Cancer Center of Kansas - Winfield
-
-
Kentucky
-
Lexington, Kentucky, Forente stater, 40536
- University of Kentucky/Markey Cancer Center
-
-
Louisiana
-
Baton Rouge, Louisiana, Forente stater, 70809
- Ochsner Health Center-Summa
-
Baton Rouge, Louisiana, Forente stater, 70809
- Hematology/Oncology Clinic LLP
-
Kenner, Louisiana, Forente stater, 70065
- Ochsner Medical Center Kenner
-
Metairie, Louisiana, Forente stater, 70006
- East Jefferson General Hospital
-
New Orleans, Louisiana, Forente stater, 70121
- Ochsner Medical Center Jefferson
-
New Orleans, Louisiana, Forente stater, 70112
- Tulane University Health Sciences Center
-
New Orleans, Louisiana, Forente stater, 70112
- University Medical Center New Orleans
-
New Orleans, Louisiana, Forente stater, 70112
- Louisiana State University Health Science Center
-
-
Maine
-
Augusta, Maine, Forente stater, 04330
- Harold Alfond Center for Cancer Care
-
Bangor, Maine, Forente stater, 04401
- Eastern Maine Medical Center
-
Rockport, Maine, Forente stater, 04856
- Penobscot Bay Medical Center
-
-
Maryland
-
Baltimore, Maryland, Forente stater, 21287
- Johns Hopkins University/Sidney Kimmel Cancer Center
-
Olney, Maryland, Forente stater, 20832
- Montgomery General Hospital-Olney
-
-
Massachusetts
-
Boston, Massachusetts, Forente stater, 02215
- Dana-Farber Cancer Institute
-
Boston, Massachusetts, Forente stater, 02118
- Boston Medical Center
-
Brighton, Massachusetts, Forente stater, 02135
- Steward Saint Elizabeth's Medical Center
-
Burlington, Massachusetts, Forente stater, 01805
- Lahey Hospital and Medical Center
-
Quincy, Massachusetts, Forente stater, 02169
- Dana Farber Community Cancer Care-Quincy
-
-
Michigan
-
Adrian, Michigan, Forente stater, 49221
- Hickman Cancer Center
-
Ann Arbor, Michigan, Forente stater, 48106-0995
- Saint Joseph Mercy Hospital
-
Ann Arbor, Michigan, Forente stater, 48109
- University Of Michigan Comprehensive Cancer Center
-
Ann Arbor, Michigan, Forente stater, 48106
- Michigan Cancer Research Consortium NCORP
-
Battle Creek, Michigan, Forente stater, 49017
- Bronson Battle Creek
-
Brighton, Michigan, Forente stater, 48114
- Saint Joseph Mercy Brighton
-
Brighton, Michigan, Forente stater, 48114
- IHA Hematology Oncology Consultants-Brighton
-
Canton, Michigan, Forente stater, 48188
- IHA Hematology Oncology Consultants-Canton
-
Canton, Michigan, Forente stater, 48188
- Saint Joseph Mercy Canton Health Center
-
Chelsea, Michigan, Forente stater, 48118
- Saint Joseph Mercy Chelsea
-
Chelsea, Michigan, Forente stater, 48118
- IHA Hematology Oncology Consultants-Chelsea
-
Detroit, Michigan, Forente stater, 48236
- Saint John Hospital and Medical Center
-
Escanaba, Michigan, Forente stater, 49829
- Green Bay Oncology - Escanaba
-
Farmington, Michigan, Forente stater, 48334
- Botsford General Hospital
-
Grand Rapids, Michigan, Forente stater, 49503
- Spectrum Health at Butterworth Campus
-
Grand Rapids, Michigan, Forente stater, 49503
- Mercy Health Saint Mary's
-
Grand Rapids, Michigan, Forente stater, 49503
- Cancer Research Consortium of West Michigan NCORP
-
Iron Mountain, Michigan, Forente stater, 49801
- Green Bay Oncology - Iron Mountain
-
Kalamazoo, Michigan, Forente stater, 49007
- West Michigan Cancer Center
-
Lansing, Michigan, Forente stater, 48912
- Sparrow Hospital
-
Muskegon, Michigan, Forente stater, 49444
- Mercy Health Mercy Campus
-
Niles, Michigan, Forente stater, 49120
- Lakeland Community Hospital
-
Pontiac, Michigan, Forente stater, 48341
- Saint Joseph Mercy Oakland
-
Port Huron, Michigan, Forente stater, 48060
- Lake Huron Medical Center
-
Reed City, Michigan, Forente stater, 49677
- Spectrum Health Reed City Hospital
-
Royal Oak, Michigan, Forente stater, 48073
- William Beaumont Hospital-Royal Oak
-
Saginaw, Michigan, Forente stater, 48601
- Saint Mary's of Michigan
-
Saint Joseph, Michigan, Forente stater, 49085
- Marie Yeager Cancer Center
-
Traverse City, Michigan, Forente stater, 49684
- Munson Medical Center
-
Troy, Michigan, Forente stater, 48098
- William Beaumont Hospital - Troy
-
Warren, Michigan, Forente stater, 48093
- Saint John Macomb-Oakland Hospital
-
Ypsilanti, Michigan, Forente stater, 48197
- IHA Hematology Oncology Consultants-Ann Arbor
-
-
Minnesota
-
Bemidji, Minnesota, Forente stater, 56601
- Sanford Clinic North-Bemidgi
-
Burnsville, Minnesota, Forente stater, 55337
- Fairview Ridges Hospital
-
Coon Rapids, Minnesota, Forente stater, 55433
- Mercy Hospital
-
Duluth, Minnesota, Forente stater, 55805
- Essentia Health Cancer Center
-
Edina, Minnesota, Forente stater, 55435
- Fairview-Southdale Hospital
-
Fergus Falls, Minnesota, Forente stater, 56537
- Lake Region Healthcare Corporation-Cancer Care
-
Fridley, Minnesota, Forente stater, 55432
- Unity Hospital
-
Maplewood, Minnesota, Forente stater, 55109
- Saint John's Hospital - Healtheast
-
Maplewood, Minnesota, Forente stater, 55109
- Minnesota Oncology Hematology PA-Maplewood
-
Minneapolis, Minnesota, Forente stater, 55415
- Hennepin County Medical Center
-
Minneapolis, Minnesota, Forente stater, 55407
- Abbott-Northwestern Hospital
-
Minneapolis, Minnesota, Forente stater, 55454
- Health Partners Inc
-
Minneapolis, Minnesota, Forente stater, 55455
- University of Minnesota/Masonic Cancer Center
-
Minneapolis, Minnesota, Forente stater, 55417
- Minneapolis Veterans Medical Center
-
Robbinsdale, Minnesota, Forente stater, 55422
- North Memorial Medical Health Center
-
Rochester, Minnesota, Forente stater, 55905
- Mayo Clinic
-
Saint Cloud, Minnesota, Forente stater, 56303
- Coborn Cancer Center at Saint Cloud Hospital
-
Saint Louis Park, Minnesota, Forente stater, 55416
- Park Nicollet Clinic - Saint Louis Park
-
Saint Louis Park, Minnesota, Forente stater, 55416
- Metro Minnesota Community Oncology Research Consortium
-
Saint Paul, Minnesota, Forente stater, 55101
- Regions Hospital
-
Saint Paul, Minnesota, Forente stater, 55102
- United Hospital
-
Shakopee, Minnesota, Forente stater, 55379
- Saint Francis Regional Medical Center
-
Stillwater, Minnesota, Forente stater, 55082
- Lakeview Hospital
-
Waconia, Minnesota, Forente stater, 55387
- Ridgeview Medical Center
-
Willmar, Minnesota, Forente stater, 56201
- Rice Memorial Hospital
-
Woodbury, Minnesota, Forente stater, 55125
- Minnesota Oncology Hematology PA-Woodbury
-
-
Mississippi
-
Jackson, Mississippi, Forente stater, 39216
- University of Mississippi Medical Center
-
-
Missouri
-
Cape Girardeau, Missouri, Forente stater, 63703
- Saint Francis Medical Center
-
Cape Girardeau, Missouri, Forente stater, 63703
- Southeast Cancer Center
-
City of Saint Peters, Missouri, Forente stater, 63376
- Siteman Cancer Center - Saint Peters
-
Columbia, Missouri, Forente stater, 65212
- University of Missouri - Ellis Fischel
-
Creve Coeur, Missouri, Forente stater, 63141
- Barnes-Jewish West County Hospital
-
Joplin, Missouri, Forente stater, 64804
- Mercy Hospital-Joplin
-
Kansas City, Missouri, Forente stater, 64128
- Kansas City Veterans Affairs Medical Center
-
Kansas City, Missouri, Forente stater, 64131
- The University of Kansas Cancer Center-South
-
Kansas City, Missouri, Forente stater, 64111
- Saint Luke's Hospital of Kansas City
-
Kansas City, Missouri, Forente stater, 64132
- Research Medical Center
-
Kansas City, Missouri, Forente stater, 64108
- Truman Medical Center
-
Kansas City, Missouri, Forente stater, 64154
- The University of Kansas Cancer Center-North
-
Lee's Summit, Missouri, Forente stater, 64064
- The University of Kansas Cancer Center-Lee's Summit
-
Rolla, Missouri, Forente stater, 65401
- Delbert Day Cancer Institute at PCRMC
-
Saint Joseph, Missouri, Forente stater, 64506
- Heartland Regional Medical Center
-
Springfield, Missouri, Forente stater, 65807
- CoxHealth South Hospital
-
Springfield, Missouri, Forente stater, 65804
- Mercy Hospital Springfield
-
St Louis, Missouri, Forente stater, 63110
- Washington University School of Medicine
-
St Louis, Missouri, Forente stater, 63131
- Missouri Baptist Medical Center
-
St Louis, Missouri, Forente stater, 63141
- Mercy Hospital Saint Louis
-
St Louis, Missouri, Forente stater, 63109
- Saint Louis Cancer and Breast Institute-South City
-
-
Montana
-
Billings, Montana, Forente stater, 59101
- Billings Clinic Cancer Center
-
Billings, Montana, Forente stater, 59101
- Saint Vincent Healthcare
-
Billings, Montana, Forente stater, 59102
- Montana Cancer Consortium NCORP
-
Bozeman, Montana, Forente stater, 59715
- Bozeman Deaconess Hospital
-
Great Falls, Montana, Forente stater, 59405
- Benefis Healthcare- Sletten Cancer Institute
-
-
Nebraska
-
Grand Island, Nebraska, Forente stater, 68803
- CHI Health Saint Francis
-
Kearney, Nebraska, Forente stater, 68847
- CHI Health Good Samaritan
-
Omaha, Nebraska, Forente stater, 68114
- Nebraska Methodist Hospital
-
Omaha, Nebraska, Forente stater, 68124
- Alegent Health Bergan Mercy Medical Center
-
Omaha, Nebraska, Forente stater, 68122
- Alegent Health Immanuel Medical Center
-
Omaha, Nebraska, Forente stater, 68130
- Alegent Health Lakeside Hospital
-
Omaha, Nebraska, Forente stater, 68131
- Creighton University Medical Center
-
-
Nevada
-
Las Vegas, Nevada, Forente stater, 89148
- Comprehensive Cancer Centers of Nevada
-
Las Vegas, Nevada, Forente stater, 89169
- Comprehensive Cancer Centers of Nevada - Central Valley
-
Las Vegas, Nevada, Forente stater, 89106
- Nevada Cancer Research Foundation CCOP
-
Reno, Nevada, Forente stater, 89502
- Renown Regional Medical Center
-
-
New Hampshire
-
Concord, New Hampshire, Forente stater, 03301
- New Hampshire Oncology Hematology PA-Concord
-
Hooksett, New Hampshire, Forente stater, 03106
- New Hampshire Oncology Hematology PA-Hooksett
-
Laconia, New Hampshire, Forente stater, 03246
- LRGHealthcare-Lakes Region General Hospital
-
-
New Jersey
-
East Orange, New Jersey, Forente stater, 07018-1095
- Veterans Adminstration New Jersey Health Care System
-
New Brunswick, New Jersey, Forente stater, 08903
- Rutgers Cancer Institute of New Jersey
-
Sparta, New Jersey, Forente stater, 07871
- Sparta Cancer Treatment Center
-
-
New Mexico
-
Albuquerque, New Mexico, Forente stater, 87102
- University of New Mexico Cancer Center
-
Albuquerque, New Mexico, Forente stater, 87102
- Lovelace Medical Center-Downtown
-
Albuquerque, New Mexico, Forente stater, 87106
- Hematology Oncology Associates
-
Las Cruces, New Mexico, Forente stater, 88011
- Memorial Medical Center - Las Cruces
-
Santa Fe, New Mexico, Forente stater, 87505
- Christus Saint Vincent Regional Cancer Center
-
-
New York
-
Brooklyn, New York, Forente stater, 11209
- Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus
-
Buffalo, New York, Forente stater, 14263
- Roswell Park Cancer Institute
-
Buffalo, New York, Forente stater, 14215
- Veterans Affairs Western New York Health Care System-Buffalo
-
East Syracuse, New York, Forente stater, 13057
- Hematology Oncology Associates of Central New York-East Syracuse
-
Elmira, New York, Forente stater, 14905
- Arnot Ogden Medical Center/Falck Cancer Center
-
Glens Falls, New York, Forente stater, 12801
- Glens Falls Hospital
-
Middletown, New York, Forente stater, 10940
- Orange Regional Medical Center
-
New York, New York, Forente stater, 10065
- Weill Medical College of Cornell University
-
New York, New York, Forente stater, 10016
- Laura and Isaac Perlmutter Cancer Center at NYU Langone
-
New York, New York, Forente stater, 10032
- Columbia University/Herbert Irving Cancer Center
-
Rochester, New York, Forente stater, 14642
- University of Rochester
-
Syracuse, New York, Forente stater, 13210
- State University of New York Upstate Medical University
-
The Bronx, New York, Forente stater, 10467-2490
- Montefiore Medical Center - Moses Campus
-
The Bronx, New York, Forente stater, 10461
- Montefiore Medical Center-Weiler Hospital
-
White Plains, New York, Forente stater, 10601
- Dickstein Cancer Treatment Center
-
-
North Carolina
-
Asheville, North Carolina, Forente stater, 28801
- Mission Hospital-Memorial Campus
-
Charlotte, North Carolina, Forente stater, 28203
- Carolinas Medical Center/Levine Cancer Institute
-
Concord, North Carolina, Forente stater, 28025
- Carolinas HealthCare System NorthEast
-
Hendersonville, North Carolina, Forente stater, 28791
- Hendersonville Hematology and Oncology at Pardee
-
Hendersonville, North Carolina, Forente stater, 28791
- Margaret R Pardee Memorial Hospital
-
Hendersonville, North Carolina, Forente stater, 28792
- Park Ridge Hospital Breast Health Center
-
Kinston, North Carolina, Forente stater, 28501
- Kinston Medical Specialists PA
-
Monroe, North Carolina, Forente stater, 28112
- Carolinas HealthCare System Union
-
Shelby, North Carolina, Forente stater, 28150
- Carolinas HealthCare System Cleveland
-
Statesville, North Carolina, Forente stater, 28677
- Iredell Memorial Hospital
-
Winston-Salem, North Carolina, Forente stater, 27104
- Southeast Clinical Oncology Research (SCOR) Consortium NCORP
-
-
North Dakota
-
Bismarck, North Dakota, Forente stater, 58501
- Sanford Bismarck Medical Center
-
Fargo, North Dakota, Forente stater, 58122
- Sanford Clinic North-Fargo
-
Fargo, North Dakota, Forente stater, 58122
- Sanford Medical Center-Fargo
-
Fargo, North Dakota, Forente stater, 58122
- Roger Maris Cancer Center
-
-
Ohio
-
Akron, Ohio, Forente stater, 44304
- Summa Akron City Hospital/Cooper Cancer Center
-
Barberton, Ohio, Forente stater, 44203
- Summa Barberton Hospital
-
Chillicothe, Ohio, Forente stater, 45601
- Adena Regional Medical Center
-
Cincinnati, Ohio, Forente stater, 45219
- The Christ Hospital
-
Cincinnati, Ohio, Forente stater, 45219
- University of Cincinnati/Barrett Cancer Center
-
Cleveland, Ohio, Forente stater, 44109
- MetroHealth Medical Center
-
Columbus, Ohio, Forente stater, 43214
- Riverside Methodist Hospital
-
Columbus, Ohio, Forente stater, 43210
- Ohio State University Comprehensive Cancer Center
-
Columbus, Ohio, Forente stater, 43219
- The Mark H Zangmeister Center
-
Columbus, Ohio, Forente stater, 43214
- Columbus Oncology and Hematology Associates Inc
-
Columbus, Ohio, Forente stater, 43215
- Grant Medical Center
-
Columbus, Ohio, Forente stater, 43222
- Mount Carmel Health Center West
-
Columbus, Ohio, Forente stater, 43215
- Columbus NCI Community Oncology Research Program
-
Dayton, Ohio, Forente stater, 45406
- Good Samaritan Hospital - Dayton
-
Dayton, Ohio, Forente stater, 45409
- Miami Valley Hospital
-
Dayton, Ohio, Forente stater, 45415
- Samaritan North Health Center
-
Dayton, Ohio, Forente stater, 45420
- Dayton NCI Community Oncology Research Program
-
Dayton, Ohio, Forente stater, 45428
- Veteran Affairs Medical Center
-
Delaware, Ohio, Forente stater, 43015
- Delaware Health Center-Grady Cancer Center
-
Findlay, Ohio, Forente stater, 45840
- Armes Family Cancer Center
-
Findlay, Ohio, Forente stater, 45840
- Orion Cancer Care
-
Franklin, Ohio, Forente stater, 45005-1066
- Atrium Medical Center-Middletown Regional Hospital
-
Franklin, Ohio, Forente stater, 45005
- Dayton Physicians LLC-Atrium
-
Kettering, Ohio, Forente stater, 45429
- Kettering Medical Center
-
Lima, Ohio, Forente stater, 45801
- Saint Rita's Medical Center
-
Marietta, Ohio, Forente stater, 45750
- Marietta Memorial Hospital
-
Maumee, Ohio, Forente stater, 43537
- Toledo Clinic Cancer Centers-Maumee
-
Oregon, Ohio, Forente stater, 43616
- Saint Charles Hospital
-
Perrysburg, Ohio, Forente stater, 43551
- Mercy Health Perrysburg Cancer Center
-
Portsmouth, Ohio, Forente stater, 45662
- Southern Ohio Medical Center
-
Springfield, Ohio, Forente stater, 45505
- Springfield Regional Medical Center
-
Toledo, Ohio, Forente stater, 43623
- Toledo Clinic Cancer Centers-Toledo
-
Toledo, Ohio, Forente stater, 43623
- Mercy Saint Anne Hospital
-
Troy, Ohio, Forente stater, 45373
- Upper Valley Medical Center
-
Westerville, Ohio, Forente stater, 43081
- Saint Ann's Hospital
-
Wpafb, Ohio, Forente stater, 45433-5529
- Wright-Patterson Medical Center
-
-
Oklahoma
-
Oklahoma City, Oklahoma, Forente stater, 73104
- University of Oklahoma Health Sciences Center
-
Tulsa, Oklahoma, Forente stater, 74146
- Oklahoma Cancer Specialists and Research Institute-Tulsa
-
-
Oregon
-
Gresham, Oregon, Forente stater, 97030
- Legacy Mount Hood Medical Center
-
Portland, Oregon, Forente stater, 97239
- Oregon Health and Science University
-
Portland, Oregon, Forente stater, 97210
- Legacy Good Samaritan Hospital and Medical Center
-
Portland, Oregon, Forente stater, 97227
- Kaiser Permanente Northwest
-
Portland, Oregon, Forente stater, 97239
- Portland Veterans Administration Medical Center
-
Tualatin, Oregon, Forente stater, 97062
- Legacy Meridian Park Hospital
-
-
Pennsylvania
-
Allentown, Pennsylvania, Forente stater, 18103
- Lehigh Valley Hospital-Cedar Crest
-
Bethlehem, Pennsylvania, Forente stater, 18017
- Lehigh Valley Hospital - Muhlenberg
-
Doylestown, Pennsylvania, Forente stater, 18901
- Doylestown Hospital
-
Hershey, Pennsylvania, Forente stater, 17033-0850
- Penn State Milton S Hershey Medical Center
-
Philadelphia, Pennsylvania, Forente stater, 19111
- Fox Chase Cancer Center
-
Philadelphia, Pennsylvania, Forente stater, 19107
- Thomas Jefferson University Hospital
-
Philadelphia, Pennsylvania, Forente stater, 19140
- Temple University Hospital
-
Scranton, Pennsylvania, Forente stater, 18508
- Hematology and Oncology Associates of North East Pennsylvania
-
West Reading, Pennsylvania, Forente stater, 19611
- Reading Hospital
-
-
South Carolina
-
Anderson, South Carolina, Forente stater, 29621
- AnMed Health Cancer Center
-
Charleston, South Carolina, Forente stater, 29425
- Medical University of South Carolina
-
Charleston, South Carolina, Forente stater, 29401
- Roper Hospital
-
Charleston, South Carolina, Forente stater, 29403
- Charleston Hematology Oncology Associates-Roper
-
Charleston, South Carolina, Forente stater, 29414
- Charleston Hematology Oncology Associates PA-St. Francis
-
Easley, South Carolina, Forente stater, 29640
- Greenville Health System Cancer Institute-Easley
-
Greenville, South Carolina, Forente stater, 29607
- Saint Francis Cancer Center
-
Greenville, South Carolina, Forente stater, 29601
- Saint Francis Hospital
-
Greenville, South Carolina, Forente stater, 29605
- Greenville Health System Cancer Institute-Faris
-
Greenville, South Carolina, Forente stater, 29605
- Greenville Memorial Hospital
-
Greenville, South Carolina, Forente stater, 29615
- Greenville Health System Cancer Institute-Eastside
-
Greenville, South Carolina, Forente stater, 29605
- Greenville Health System Cancer Institute-Butternut
-
Greenwood, South Carolina, Forente stater, 29646
- Self Regional Healthcare
-
Greer, South Carolina, Forente stater, 29650
- Greenville Health System Cancer Institute-Greer
-
Seneca, South Carolina, Forente stater, 29672
- Greenville Health System Cancer Institute-Seneca
-
Spartanburg, South Carolina, Forente stater, 29303
- Spartanburg Medical Center
-
Spartanburg, South Carolina, Forente stater, 29307
- Greenville Health System Cancer Institute-Spartanburg
-
-
South Dakota
-
Sioux Falls, South Dakota, Forente stater, 57117-5134
- Sanford USD Medical Center - Sioux Falls
-
Sioux Falls, South Dakota, Forente stater, 57104
- Sanford Cancer Center-Oncology Clinic
-
-
Tennessee
-
Knoxville, Tennessee, Forente stater, 37920
- University of Tennessee - Knoxville
-
Nashville, Tennessee, Forente stater, 37208
- Meharry Medical College
-
-
Texas
-
Houston, Texas, Forente stater, 77030
- M D Anderson Cancer Center
-
Houston, Texas, Forente stater, 77026-1967
- Lyndon Baines Johnson General Hospital
-
Houston, Texas, Forente stater, 77030
- Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
-
Houston, Texas, Forente stater, 77030
- Michael E DeBakey VA Medical Center
-
Houston, Texas, Forente stater, 77094
- MD Anderson Regional Care Center-Katy
-
Houston, Texas, Forente stater, 77030
- Ben Taub General Hospital
-
Nassau Bay, Texas, Forente stater, 77058
- MD Anderson Regional Care Center-Bay Area
-
Sugar Land, Texas, Forente stater, 77478
- MD Anderson Regional Care Center-Sugar Land
-
The Woodlands, Texas, Forente stater, 77384
- MD Anderson Regional Care Center-The Woodlands
-
-
Utah
-
Salt Lake City, Utah, Forente stater, 84112
- Huntsman Cancer Institute/University of Utah
-
-
Virginia
-
Falls Church, Virginia, Forente stater, 22042
- INOVA Fairfax Hospital
-
Lynchburg, Virginia, Forente stater, 24501
- Lynchburg Hematology-Oncology Clinic
-
Martinsville, Virginia, Forente stater, 24115
- Memorial Hospital Of Martinsville
-
Richmond, Virginia, Forente stater, 23298
- Virginia Commonwealth University/Massey Cancer Center
-
South Hill, Virginia, Forente stater, 23970
- VCU Community Memorial Health Center
-
Winchester, Virginia, Forente stater, 22601
- Shenandoah Oncology Associates PC
-
-
Washington
-
Auburn, Washington, Forente stater, 98001
- MultiCare Auburn Medical Center
-
Bellingham, Washington, Forente stater, 98225
- PeaceHealth Saint Joseph Medical Center
-
Burien, Washington, Forente stater, 98166
- Highline Medical Center-Main Campus
-
Everett, Washington, Forente stater, 98201
- Providence Regional Cancer Partnership
-
Gig Harbor, Washington, Forente stater, 98335
- MultiCare Gig Harbor Medical Park
-
Kennewick, Washington, Forente stater, 99336
- Kadlec Clinic Hematology and Oncology
-
Kirkland, Washington, Forente stater, 98034
- Seattle Cancer Care Alliance at EvergreenHealth
-
Mount Vernon, Washington, Forente stater, 98274
- Skagit Valley Hospital
-
Port Townsend, Washington, Forente stater, 98368
- Jefferson Healthcare
-
Puyallup, Washington, Forente stater, 98372
- MultiCare Good Samaritan Hospital
-
Seattle, Washington, Forente stater, 98109
- Fred Hutchinson Cancer Research Center
-
Seattle, Washington, Forente stater, 98195
- University of Washington Medical Center
-
Seattle, Washington, Forente stater, 98104
- Minor and James Medical PLLC
-
Seattle, Washington, Forente stater, 98112
- Group Health Cooperative-Seattle
-
Seattle, Washington, Forente stater, 98122-4307
- Swedish Medical Center-First Hill
-
Spokane, Washington, Forente stater, 99204
- Rockwood Cancer Treatment Center-DHEC-Downtown
-
Spokane, Washington, Forente stater, 99220
- Rockwood Clinic
-
Spokane Valley, Washington, Forente stater, 99216
- Rockwood Clinic Cancer Treatment Center-Valley
-
Tacoma, Washington, Forente stater, 98431
- Madigan Army Medical Center
-
Tacoma, Washington, Forente stater, 98405
- MultiCare Tacoma General Hospital
-
Tacoma, Washington, Forente stater, 98405
- Northwest NCI Community Oncology Research Program
-
Vancouver, Washington, Forente stater, 98686
- Legacy Salmon Creek Hospital
-
Walla Walla, Washington, Forente stater, 99362
- Providence Saint Mary Regional Cancer Center
-
-
West Virginia
-
Charleston, West Virginia, Forente stater, 25304
- West Virginia University Charleston
-
Huntington, West Virginia, Forente stater, 25701
- Edwards Comprehensive Cancer Center
-
-
Wisconsin
-
Antigo, Wisconsin, Forente stater, 54409
- Langlade Hospital and Cancer Center
-
Burlington, Wisconsin, Forente stater, 53105
- Aurora Cancer Care-Southern Lakes VLCC
-
Chippewa Falls, Wisconsin, Forente stater, 54729
- Marshfield Clinic-Chippewa Center
-
Eau Claire, Wisconsin, Forente stater, 54701
- Marshfield Clinic Cancer Center at Sacred Heart
-
Eau Claire, Wisconsin, Forente stater, 54701
- Sacred Heart Hospital
-
Fond du Lac, Wisconsin, Forente stater, 54937
- Aurora Health Center-Fond du Lac
-
Germantown, Wisconsin, Forente stater, 53022
- Aurora Health Care Germantown Health Center
-
Grafton, Wisconsin, Forente stater, 53024
- Aurora Cancer Care-Grafton
-
Green Bay, Wisconsin, Forente stater, 54311
- Aurora BayCare Medical Center
-
Green Bay, Wisconsin, Forente stater, 54301
- Saint Vincent Hospital Cancer Center Green Bay
-
Green Bay, Wisconsin, Forente stater, 54303
- Saint Vincent Hospital Cancer Center at Saint Mary's
-
Green Bay, Wisconsin, Forente stater, 54303
- Green Bay Oncology Limited at Saint Mary's Hospital
-
Green Bay, Wisconsin, Forente stater, 54301-3526
- Green Bay Oncology at Saint Vincent Hospital
-
Johnson Creek, Wisconsin, Forente stater, 53038
- UW Cancer Center Johnson Creek
-
Kenosha, Wisconsin, Forente stater, 53142
- Aurora Cancer Care-Kenosha South
-
La Crosse, Wisconsin, Forente stater, 54601
- Gundersen Lutheran Medical Center
-
Ladysmith, Wisconsin, Forente stater, 54848
- Marshfield Clinic - Ladysmith Center
-
Madison, Wisconsin, Forente stater, 53792
- University of Wisconsin Hospital and Clinics
-
Manitowoc, Wisconsin, Forente stater, 54221
- Holy Family Memorial Hospital
-
Marinette, Wisconsin, Forente stater, 54143
- Aurora Bay Area Medical Group-Marinette
-
Marinette, Wisconsin, Forente stater, 54143
- Vince Lombardi Cancer Clinic-Marinette
-
Marshfield, Wisconsin, Forente stater, 54449
- Marshfield Clinic
-
Marshfield, Wisconsin, Forente stater, 54449
- Saint Joseph's Hospital
-
Milwaukee, Wisconsin, Forente stater, 53226
- Froedtert and The Medical College of Wisconsin
-
Milwaukee, Wisconsin, Forente stater, 53209
- Aurora Cancer Care-Milwaukee
-
Milwaukee, Wisconsin, Forente stater, 53215
- Aurora Saint Luke's Medical Center
-
Milwaukee, Wisconsin, Forente stater, 53233
- Aurora Sinai Medical Center
-
Minocqua, Wisconsin, Forente stater, 54548
- Marshfield Clinic-Minocqua Center
-
New Richmond, Wisconsin, Forente stater, 54017
- Cancer Center of Western Wisconsin
-
Oconto Falls, Wisconsin, Forente stater, 54154
- Green Bay Oncology - Oconto Falls
-
Oshkosh, Wisconsin, Forente stater, 54904
- Vince Lombardi Cancer Clinic - Oshkosh
-
Racine, Wisconsin, Forente stater, 53406
- Aurora Cancer Care-Racine
-
Rhinelander, Wisconsin, Forente stater, 54501
- Saint Mary's Hospital
-
Rhinelander, Wisconsin, Forente stater, 54501
- Marshfield Clinic at James Beck Cancer Center
-
Rice Lake, Wisconsin, Forente stater, 54868
- Marshfield Clinic-Rice Lake Center
-
Sheboygan, Wisconsin, Forente stater, 53081
- Vince Lombardi Cancer Clinic-Sheboygan
-
Sheboygan, Wisconsin, Forente stater, 53081
- HSHS Saint Nicholas Hospital
-
Stevens Point, Wisconsin, Forente stater, 54482
- Marshfield Clinic Stevens Point Center
-
Stevens Point, Wisconsin, Forente stater, 54481
- Saint Michael's Hospital
-
Stevens Point, Wisconsin, Forente stater, 54481
- Marshfield Clinic Cancer Care at Saint Michael's Hospital
-
Sturgeon Bay, Wisconsin, Forente stater, 54235-1495
- Saint Vincent Hospital Cancer Center at Sturgeon Bay
-
Sturgeon Bay, Wisconsin, Forente stater, 54235
- Green Bay Oncology - Sturgeon Bay
-
Summit, Wisconsin, Forente stater, 53066
- Aurora Medical Center in Summit
-
Two Rivers, Wisconsin, Forente stater, 54241
- Vince Lombardi Cancer Clinic-Two Rivers
-
Waukesha, Wisconsin, Forente stater, 53188
- Aurora Cancer Care-Waukesha
-
Wausau, Wisconsin, Forente stater, 54401
- Aspirus Regional Cancer Center
-
Wausau, Wisconsin, Forente stater, 54401
- Marshfield Clinic-Wausau Center
-
Wauwatosa, Wisconsin, Forente stater, 53226
- Aurora Cancer Care-Milwaukee West
-
West Allis, Wisconsin, Forente stater, 53227
- Aurora West Allis Medical Center
-
Weston, Wisconsin, Forente stater, 54476
- Diagnostic and Treatment Center
-
Weston, Wisconsin, Forente stater, 54476
- Marshfield Clinic - Weston Center
-
Wisconsin Rapids, Wisconsin, Forente stater, 54494
- Marshfield Clinic - Wisconsin Rapids Center
-
Wisconsin Rapids, Wisconsin, Forente stater, 54494
- Aspirus UW Cancer Center
-
-
Wyoming
-
Cody, Wyoming, Forente stater, 82414
- Billings Clinic-Cody
-
-
Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
18 år og eldre (Voksen, Eldre voksen)
Tar imot friske frivillige
Nei
Beskrivelse
Inklusjonskriterier:
- Klinisk diagnose av metastatisk prostatakreft.
- Serum testosteron innenfor institusjonelle grenser for normalen.
- PSA ≥ 2 ng/ml innen 90 dager før oppstart av androgenmangel. terapi (for tidlig induksjon) eller før registrering (for sen induksjon).
- DEXA-skanning innen 2 år før registrering.
- EKG innen 42 dager før registrering og QTc-intervall ≤ 460 msek.
- LVEF innen 42 dager før registrering og innenfor institusjonelle normer.
- Tilstrekkelig leverfunksjon som påvist av bilirubin ≤ 2 x institusjonell øvre normalgrense (ULN), SGOT (AST) og SGPT (ALT) ≤ 3 x institusjonell ULN, eller ≤ 5 x institusjonell ULN hvis levermetastaser er tilstede.
- Tilstrekkelig nyrefunksjon som vist ved beregnet kreatininclearance ≥ 40 ml/min.
- Tilstrekkelig hematologisk funksjon som påvist av leukocytter ≥ 3 000/mcL, absolutt nøytrofiltall (ANC) ≥ 1 500/mcL, hemoglobin ≥ 9 g/dL og blodplater ≥ 100 000/mcL.
- Zubrod ytelsesstatus på 0 - 2. Zubrod ytelsesstatus 3 vil være tillatt hvis kun fra beinsmerter.
- ≥ 18 år.
- Menn med reproduksjonspotensial og de som er kirurgisk sterilisert (dvs. postvasektomi) må samtykke i å praktisere effektiv barriereprevensjon eller samtykke i å avstå fra samleie mens de mottar behandling i denne studien og i minst 4 måneder etter at protokollbehandlingen avsluttes.
Ekskluderingskriterier:
- Kjente hjernemetastaser.
- Ikke mer enn 36 måneder med tidligere neoadjuvant og/eller adjuvant hormonbehandling.
- ≥ 6 måneder siden avsluttet behandling med androgendeprivasjon.
- Tidligere eller samtidig behandling med ketokonazol, aminoglutetimid eller abirateronacetat eller enzalutamid (MDV3100). Samtidig megestrol for hetetokter er tillatt.
- Tidligere kjemoterapi for behandling av metastatisk prostatakreft. Forutgående kjemoterapi i neoadjuvant eller adjuvant setting er tillatt.
- ≥ 2 år siden fullført kjemoterapi i neoadjuvant eller adjuvant setting.
- Samtidig bruk av eksperimentell terapi er ikke tillatt.
- ≥ 30 dager siden tidligere medisinsk kastrering for metastatisk prostatakreft.
- Hvis kastrasjonsmetoden er en LHRH-agonist, må pasienten være villig til å fortsette bruken av LHRH og legge til bicalutamid eller TAK-700 under protokollbehandling.
- Hvis pasienten var på et antiandrogen (f.eks. bicalutamid, flutamid), må pasienten være villig til å gå over til bicalutamid eller TAK-700 (i henhold til randomisering).
- Tidligere bilateral orkiektomi.
- Samtidig bruk av LHRH-antagonister (f.eks. Degarelix)
- Hjertesykdom grad III/IV (som definert av NYHA-kriteriene), tromboembolisk hendelse, ustabil angina pectoris, hjerteinfarkt innen 6 måneder eller alvorlig ukontrollert hjertearytmi.
- Ukontrollert hypertensjon (definert som blodtrykk > 160 mmHg systolisk og > 90 mmHg diastolisk ved 2 separate målinger med ikke mer enn 60 minutters mellomrom under screeningbesøket) til tross for passende medisinsk behandling.
- Kjent infeksjon med humant immunsviktvirus (HIV), aktiv kronisk hepatitt B eller C, livstruende sykdom som ikke er relatert til kreft, eller enhver alvorlig medisinsk eller psykiatrisk sykdom som etter etterforskerens mening potensielt kan forstyrre deltakelsen i denne studien.
- Anamnese med primær og sekundær binyrebarkinsuffisiens.
- Overfølsomhet overfor TAK-700, overfor TAK-700-metabolitter, overfor bicalutamid eller overfor LHRH-agonister.
- Gastrointestinal (GI) sykdom eller GI-prosedyre som kan forstyrre GI-absorpsjonen eller toleransen til TAK-700, inkludert problemer med å svelge orale medisiner.
- Ingen annen tidligere malignitet er tillatt bortsett fra følgende: adekvat behandlet basalcelle- eller plateepitelhudkreft, adekvat behandlet kreft i stadium I eller II som pasienten for øyeblikket er i fullstendig remisjon fra, eller annen kreft som pasienten har vært syk fra- gratis i 5 år.
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Behandling
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Ingen (Open Label)
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
|---|---|
|
Eksperimentell: ADT + TAK-700
LHRH-agonist - gitt som godkjent for androgenmangel i en dose som er nødvendig for å opprettholde kastratnivåer og tilsvarende 22,5 mg Leuprolide IM hver 3. måned. TAK-700, 300 mg, PO, to ganger daglig |
300 mg, PO, to ganger daglig
Andre navn:
|
|
Aktiv komparator: ADT + Bicalutamid
LHRH-agonist - gitt som godkjent for androgenmangel i en dose som er nødvendig for å opprettholde kastratnivåer og tilsvarende 22,5 mg Leuprolide IM hver 3. måned. Bicalutamid, 50 mg, PO, q daglig |
50 mg, PO, q daglig
Andre navn:
|
Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
Totalt overlevelse
Tidsramme: Varighet av behandling og oppfølging til død eller 9 år etter studien starter
|
Generell overlevelse er definert som tiden fra tilfeldig tildeling til dødsdato fra enhver årsak
|
Varighet av behandling og oppfølging til død eller 9 år etter studien starter
|
Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
PSA-responsrater
Tidsramme: 7 måneder etter randomisering
|
Prostataspesifikt antigen (PSA) responsrater ble delt inn i fullstendig respons (CR: PSA < 0,2 ng/ml), delvis respons (PR: PSA mellom 0,2 og 4,0 ng/ml) og ingen respons (NR: PSA > 4,0 ng /mL) ved et 7-måneders landemerke etter tilfeldig tildeling.
|
7 måneder etter randomisering
|
|
Langsiktig overlevelse
Tidsramme: Etter 10 års oppfølging
|
Langtidsoverlevelse er definert som tiden fra tilfeldig tildeling til dødsdato uansett årsak
|
Etter 10 års oppfølging
|
|
Progresjonsfri overlevelse
Tidsramme: Varighet av behandling og oppfølging til død eller 9 år etter studien starter
|
Progresjonsfri overlevelse (PFS) er definert som tiden fra tilfeldig tildeling til første dokumentasjon av PSA -progresjon, radiologisk progresjon, klinisk progresjon eller død, avhengig av hva som skjedde først. PSA -progresjon er definert som en ≥25% økning og og absolutt økning på siste 2 ng/ml fra Nadir PSA (eller fra baseline PSA hvis det ikke var noe fall i PSA etter startbehandling). Radiologisk progresjon er definert som to eller flere nye lesjoner på radionuklidbenskanninger. Klinisk progresjon er definert ved bruk av responsevalueringskriteriene i faste svulster (RECIST V1.0), som en 20% økning i summen av den lengste diameteren til mållesjoner, eller en målbar økning i en ikke-mållesjon, eller utseendet til nye lesjoner. |
Varighet av behandling og oppfølging til død eller 9 år etter studien starter
|
|
Antall deltakere med GR 3 til 5 bivirkninger som er relatert til studiemedisiner
Tidsramme: Varighet av behandling og oppfølging til død eller 9 år etter studien starter
|
Bare bivirkninger som muligens er, sannsynligvis eller definitivt relatert til studiemedisin rapporteres. Bivirkninger blir gradert ved hjelp av de vanlige terminologikriteriene for bivirkninger (CTCAE v4.0) der karakteren refererer til alvorlighetsgraden av AE. Grad 3: alvorlig eller medisinsk signifikant, men ikke umiddelbart livstruende; sykehusinnleggelse eller forlengelse av sykehusinnleggelse indikert; deaktivere; begrenser egenomsorg. Grad 4: livstruende konsekvenser; Hastighetsinngrep indikert. Grad 5: Død relatert til AE. |
Varighet av behandling og oppfølging til død eller 9 år etter studien starter
|
Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Sponsor
Etterforskere
- Hovedetterforsker: Neeraj Agarwal, M.D., University of Utah
Publikasjoner og nyttige lenker
Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.
Generelle publikasjoner
- Agarwal N, Tangen CM, Hussain MHA, Gupta S, Plets M, Lara PN, Harzstark AL, Twardowski PW, Paller CJ, Zylla D, Zibelman MR, Levine E, Roth BJ, Goldkorn A, Vaena DA, Kohli M, Crispino T, Vogelzang NJ, Thompson IM Jr, Quinn DI. Orteronel for Metastatic Hormone-Sensitive Prostate Cancer: A Multicenter, Randomized, Open-Label Phase III Trial (SWOG-1216). J Clin Oncol. 2022 Oct 1;40(28):3301-3309. doi: 10.1200/JCO.21.02517. Epub 2022 Apr 21.
- Gebrael G, Jo Y, Swami U, Plets M, Hage Chehade C, Narang A, Gupta S, Myint ZW, Sayegh N, Tangen CM, Hussain M, Dorff T, Lara PN Jr, Lerner SP, Thompson I, Agarwal N. Bone Pain and Survival Among Patients With Metastatic, Hormone-Sensitive Prostate Cancer: A Secondary Analysis of the SWOG-1216 Trial. JAMA Netw Open. 2024 Jul 1;7(7):e2419966. doi: 10.1001/jamanetworkopen.2024.19966.
- Lara PN Jr, Mayerson E, Gertz E, Tangen C, Goldkorn A, van Loan M, Hussain M, Gupta S, Zhang J, Parikh M, Twardowski P, Quinn DI, LeBlanc M, Thompson I, Agarwal N. Markers of bone metabolism and overall survival in men with bone-metastatic hormone sensitive prostate cancer (HSPC): A subset analysis of SWOG S1216, a phase III trial of androgen deprivation with or without orteronel. Prostate Cancer Prostatic Dis. 2024 Sep;27(3):566-570. doi: 10.1038/s41391-024-00813-3. Epub 2024 Feb 29.
- Sayegh N, Swami U, Jo Y, Gebrael G, Haaland B, Gupta S, Plets M, Hussain MHA, Quinn DI, Lara PN Jr, Thompson IM Jr, Agarwal N. Race and Treatment Outcomes in Patients With Metastatic Castration-Sensitive Prostate Cancer: A Secondary Analysis of the SWOG 1216 Phase 3 Trial. JAMA Netw Open. 2023 Aug 1;6(8):e2326546. doi: 10.1001/jamanetworkopen.2023.26546.
Hjelpsomme linker
Studierekorddatoer
Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.
Studer hoveddatoer
Studiestart (Faktiske)
8. mars 2013
Primær fullføring (Faktiske)
8. mars 2022
Studiet fullført (Faktiske)
9. september 2025
Datoer for studieregistrering
Først innsendt
8. mars 2013
Først innsendt som oppfylte QC-kriteriene
8. mars 2013
Først lagt ut (Antatt)
13. mars 2013
Oppdateringer av studieposter
Sist oppdatering lagt ut (Antatt)
31. desember 2025
Siste oppdatering sendt inn som oppfylte QC-kriteriene
10. desember 2025
Sist bekreftet
1. desember 2025
Mer informasjon
Begreper knyttet til denne studien
Nøkkelord
Ytterligere relevante MeSH-vilkår
- Urogenitale sykdommer
- Kjønnssykdommer
- Genitale neoplasmer, hanner
- Urogenitale neoplasmer
- Neoplasmer etter nettsted
- Neoplasmer
- Kjønnssykdommer, mannlige
- Prostata sykdommer
- Mannlige urogenitale sykdommer
- Prostatiske neoplasmer
- Antineoplastiske midler
- Fysiologiske effekter av legemidler
- Hormoner, hormonsubstitutter og hormonantagonister
- Hormonantagonister
- Androgenantagonister
- bicalutamide
- orteronel
Andre studie-ID-numre
- S1216
- SWOG-S1216 (Annet stipend/finansieringsnummer: U10CA180888)
- NCI-2012-02876 (Annen identifikator: NCI)
Plan for individuelle deltakerdata (IPD)
Planlegger du å dele individuelle deltakerdata (IPD)?
JA
IPD-planbeskrivelse
https://swog.org/Visitors/Download/Policies/Policy43.pdf
Studiedata/dokumenter
-
Datasett for individuell deltaker
Informasjonskommentarer: Velg individuelle pasientnivådata fra denne studien kan bes om fra NCTN/NCORP Data Archive
Legemiddel- og utstyrsinformasjon, studiedokumenter
Studerer et amerikansk FDA-regulert medikamentprodukt
Ja
Studerer et amerikansk FDA-regulert enhetsprodukt
Nei
Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .