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Evalueringen av Bococizumab (PF-04950615;RN316) for å redusere forekomsten av store kardiovaskulære hendelser hos høyrisikopersoner (SPIRE-1)

14. juni 2018 oppdatert av: Pfizer

Fase 3 multisenter, dobbeltblind, randomisert, placebokontrollert, parallell gruppeevaluering av effektiviteten, sikkerheten og toleransen til Bococizumab (Pf-04950615) for å redusere forekomsten av store kardiovaskulære hendelser hos høyrisikopersoner.

Denne studien evaluerer PCSK9-hemmeren, Bococizumab (PF-04950615;RN316), sammenlignet med placebo, for å redusere forekomsten av alvorlige kardiovaskulære hendelser, inkludert kardiovaskulær død, hjerteinfarkt, hjerneslag og ustabil angina som krever akutt revaskularisering, hos høyrisikopersoner som mottar bakgrunnslipidsenkende behandling og har kolesterollaboratorieverdier på LDL-C >/= 70 mg/dL (1,8 mmol/L) eller ikke-HDL-C >/= 100 mg/dL (2,6 mmol/L).

Studieoversikt

Status

Avsluttet

Forhold

Hjerte-og karsykdommer

Intervensjon / Behandling

Detaljert beskrivelse

Forsøket ble avsluttet for tidlig 1. november 2016 på grunn av den nye kliniske profilen og det utviklende behandlings- og markedslandskapet for lipidsenkende midler. Disse indikerte at bococizumab sannsynligvis ikke ville gi verdi til pasienter, leger eller aksjonærer. Beslutningen var ikke basert på en anbefaling fra den uavhengige dataovervåkingskomiteen om å stoppe programmet.

Studietype

Intervensjonell

Registrering (Faktiske)

16784

Fase

Fase 3

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Argentina
- - C.a.b.a., Argentina, C1119ACN
    - CIPREC - Centro de Investigacion y Prevencion Cardiovascular S.A.
  - Ciudad Autonoma De B. Aires, Argentina, C1405BUB
    - Cicemo - Consultorio de Investigaciones Clinicas E.M.O. S.R.L.
  - Ciudad Autonoma De Buenos Aires, Argentina, C1405BCK
    - Universidad Maimonides
  - Ciudad Autonoma de B. Aires, Argentina, C1093AAS
    - Instituto de Cardiología y Cirugía Cardiovascular - Fundación Favaloro
  - Ciudad Autonoma de B. Aires, Argentina, C1428ART
    - Instituto Cardiovascular de Buenos Aires
  - Ciudad Autonoma de Buenos Aires, Argentina, C1179AAB
    - Investigaciones Medicas IMOBA S.R.L.
  - Ciudad Autonoma de Buenos Aires, Argentina, C1430CKE
    - Centro de Investigacion: AXISMED S.R.L.
  - Cordoba, Argentina, X5003DCE
    - Instituto Medico DAMIC S.R.L.
  - Cordoba, Argentina, X5000BNB
    - ILAIM Instituto Latinoamericano de Investigaciones Medicas
  - Cordoba, Argentina, X5000EPU
    - Clinico Chutro SRL
  - Cordoba, Argentina, X5000EVQ
    - Centro de Investigaciones Clinicas "Instituto del Corazon"
  - Cordoba, Argentina, x5002AOQ
    - Clínica Privada Colombo
  - Cordoba, Argentina, X5006IKK
    - Centro Medico Luquez
  - Cordoba, Argentina, X5008KKF
    - Ipac Caraffa
  - Corrientes, Argentina, 3400
    - Instituto de Cardiologia de Corrientes "Juana Fca. Cabral"
  - Mendoza, Argentina, 5500
    - Hospital Central de Mendoza
  - Salta, Argentina, 4400
    - Cordis S.A.
  - Salta, Argentina, A4406BPF
    - Centro Cardiovascular Salta
  - San Luis, Argentina, D5702JRS
    - Instituto Cardiovascular San Luis A.E.
- Buenos Aires
  - Bahia Blanca, Buenos Aires, Argentina, B8000FTD
    - Instituto de Investigaciones Clínicas Bahia Blanca
  - Bahia Blanca, Buenos Aires, Argentina, B8001BXM
    - Hospital Italiano Regional Del Sur
  - Ciudad Autonoma de B. Aires, Buenos Aires, Argentina, C1280AEB
    - Hospital Britanico de Buenos Aires
  - Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, C1425DES
    - Cedic - Consultorios Medicos
  - La Plata, Buenos Aires, Argentina, B1902COS
    - Framingham Centro Medico
  - Lanus Este, Buenos Aires, Argentina, B1824KAJ
    - CIMeL CHAHIN CHAHIN S.A.
  - Mar del Plata, Buenos Aires, Argentina, B7600FZN
    - Instituto de Investigaciones Clinicas Mar del Plata
  - Quilmes, Buenos Aires, Argentina, B1878GEG
    - Instituto de Investigaciones Clinicas Quilmes
  - Ramos Mejia, Buenos Aires, Argentina, B1704ETD
    - Dim Clinica Privada
  - Zarate, Buenos Aires, Argentina, B2800DGH
    - Instituto de Investigaciones Clínicas Zárate
- C.a.b.a.
  - C.a.b.a, C.a.b.a., Argentina, C1425AGC
    - Consultorios Asociados de Endocrinología e Investigación Clínica Aplicada
- Caba
  - C.a.b.a, Caba, Argentina, C1023AAB
    - STAT Research S.A.
- Cordoba
  - Villa Maria, Cordoba, Argentina, 5901
    - Clinica Privada de Especialidades Medicas
- Mendoza
  - Godoy Cruz, Mendoza, Argentina, M5501ARP
    - CIPADI Centro Integral de Prevención y Atención en Diabetes
- PCIA DE Buenos Aires
  - Bahia Blanca, PCIA DE Buenos Aires, Argentina, B8001DDU
    - Hospital Interzonal Gral. de Agudos Dr. Jose Penna
  - Ciudadela, PCIA DE Buenos Aires, Argentina, 1702
    - IMEP Instituto Medico Elsa Perez
  - Moron, PCIA DE Buenos Aires, Argentina, B1708CGU
    - Instituto Medico Aguero
  - San Martin, PCIA DE Buenos Aires, Argentina, B1650CSQ
    - Corporacion Medica de San Martin
- PCIA DE Chaco
  - Resistencia, PCIA DE Chaco, Argentina, H3500CDM
    - Cordis - Instituto del Corazon
- PCIA DE Formosa
  - Formosa, PCIA DE Formosa, Argentina, 3600
    - Hospital de Alta Complejidad "Pte. Juan Domingo Perón"
- PCIA DE Santa FE
  - Santa Fe, PCIA DE Santa FE, Argentina, S3000EOZ
    - Hospital Provincial Dr. Jose Maria Cullen
  - Santa Fe, PCIA DE Santa FE, Argentina, S3000FWO
    - Centro de Investigaciones Clinicas del Litoral S.R.L.
  - Santa Fe, PCIA DE Santa FE, Argentina, S3004CVS
    - Cedir S.A - Centro De Diagnostico Y Rehabilitacion S.A.
- PCIA DE Tucuman
  - San Miguel De Tucuman, PCIA DE Tucuman, Argentina, T4000IFL
    - Centro Modelo de Cardiologia
- Pcia. DE Santa FE
  - Rosario, Pcia. DE Santa FE, Argentina, S2000CFK
    - Instituto de Hematologia y Medicina Clinica "Dr. Ruben A. Davoli"
- Provincia DE Buenos Aires
  - Coronel Suarez, Provincia DE Buenos Aires, Argentina, B7540GHD
    - Clinica Coronel Suarez S.A.
- Provincia DE Santa FE
  - Rosario, Provincia DE Santa FE, Argentina, S2000QID
    - Instituto Medico CENICLAR - Central de Investigaciones Clinicas Argentina -Sanatorio de la Mujer
- Santa FE
  - Rosario, Santa FE, Argentina, S2000CVD
    - Instituto de Investigaciones Clinicas Rosario
- Tucuman
  - San Miguel de Tucuman, Tucuman, Argentina, T4000IAF
    - Centro Medico CCBR Tucuman
Australia
- Australian Capital Territory
  - Garran, Australian Capital Territory, Australia, 2605
    - Canberra Hospital
- New South Wales
  - Camperdown, New South Wales, Australia, 2050
    - Royal Prince Alfred Hospital
  - Camperdown, New South Wales, Australia, 2050
    - Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders
  - Erina, New South Wales, Australia, 2250
    - Central Coast Neurosciences Research
  - Gosford, New South Wales, Australia, 2250
    - Gosford Hospital
  - Maroubra, New South Wales, Australia, 2035
    - Australian Clinical Research Network
  - St Leonards, New South Wales, Australia, 2065
    - Royal North Shore Hospital
- Queensland
  - Chermside, Queensland, Australia, 4032
    - Holy Spirit Northside Private Hospital Limited
  - Herston, Queensland, Australia, 4029
    - Royal Brisbane and Women's Hospital
  - Milton, Queensland, Australia, 4064
    - Core Research Group Pty Ltd
  - Redcliffe, Queensland, Australia, 4020
    - Redcliffe Hospital
  - Sherwood, Queensland, Australia, 4075
    - AusTrials Pty Ltd
  - Southport, Queensland, Australia, 4215
    - Gold Coast University Hospital
- South Australia
  - Ashford, South Australia, Australia, 5035
    - SA Heart
  - Ashford, South Australia, Australia, 5035
    - Adelaide Medical Research
  - Daws Park, South Australia, Australia, 5041
    - Southern Adelaide Diabetes and Endocrine Service
  - Elizabeth Vale, South Australia, Australia, 5112
    - Department of Cardiology, Lyell McEwin Hospital
  - Fullarton, South Australia, Australia, 5063
    - Heart and Vascular Research
- Tasmania
  - Launceston, Tasmania, Australia, 7250
    - Launceston General Hospital
- Victoria
  - Box Hill, Victoria, Australia, 3128
    - Eastern Health - Box Hill Hospital
  - Epping, Victoria, Australia, 3076
    - The Northern Hospital
  - Geelong, Victoria, Australia, 3220
    - Barwon Health-The Geelong Hospital
  - Heidelberg West, Victoria, Australia, 3081
    - Austin Health - Heidelberg Repatriation Hospital
  - Melbourne, Victoria, Australia, 3004
    - Alfred Hospital
  - Parkville, Victoria, Australia, 3050
    - Royal Melbourne Hospital
- Western Australia
  - Fremantle, Western Australia, Australia, 6160
    - Fremantle Hospital
  - Joondalup, Western Australia, Australia, 6027
    - Joondalup Cardiovascular Trials Foundation Inc.
  - Joondalup, Western Australia, Australia, 6027
    - HPS Pharmacies
  - Nedlands, Western Australia, Australia, 6009
    - Sir Charles Gairdner Hospital, Heart Research Institute
Belgia
- - Antwerpen, Belgia, 2020
    - ZNA Campus Middelheim
  - Bonheiden, Belgia, 2820
    - Imeldaziekenhuis Bonheiden
  - Brugge, Belgia, 8000
    - A.Z. St.Jan AV Brugge
  - Brussels, Belgia, 1090
    - University Hospital Brussels - Centrum voor hart- en vaatziekten
  - Brussels, Belgia, 1090
    - University Hospital Brussels- Diabeteskliniek
  - De Pinte, Belgia, 9840
    - Private Practice 'Cardiovascular Detection Center'
  - Genk, Belgia, 3600
    - ZOL Campus Sint-Jan
  - Gent, Belgia, 9000
    - AZ Maria Middelares
  - Gilly, Belgia, 6060
    - Grand Hopital de Charleroi, Site St-Joseph
  - Hasselt, Belgia, 3500
    - Jessa Ziekenhuis
  - Hasselt, Belgia, 3500
    - Hygeia
  - Heusden-Zolder, Belgia, 3550
    - Sint-Franciskusziekenhuis
  - Huy, Belgia, 4500
    - Centre Hospitalier Regional de Huy
  - Ieper, Belgia, 8900
    - Jan Yperman Ziekenhuis, Cardiology
  - Leuven, Belgia, 3000
    - Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg
  - Leuven, Belgia, 3000
    - University hospitals Leuven - Cardiology department
  - Liege, Belgia, 4000
    - Centre Hospitalier Universitaire de Liège
  - Liege, Belgia, 4000
    - Centre Hospitalier Chretien
  - Linkebeek, Belgia, 1630
    - Huisartsenpraktijk Medilink
  - Massemen, Belgia, 9230
    - Huisartsenpraktijk Luc Capiau
  - Mechelen, Belgia, 2800
    - AZ Sint-Maarten
  - Mons, Belgia, 7000
    - C.H.U. Ambroise Paré
  - Overpelt, Belgia, 3900
    - Mariaziekenhuis vzw
  - Sint-Niklaas, Belgia, 9100
    - AZ Nikolaas
  - Tienen, Belgia, 3300
    - Dr. Luc De Wolf - Private Practice
- Antwerpen
  - Brasschaat, Antwerpen, Belgia, 2930
    - VZW Algemeen Ziekenhuis KLINA
  - Turnhout, Antwerpen, Belgia, 2300
    - AZ Turnhout - campus St. Elisabeth
- Brabant Flamand
  - Anderlecht, Brabant Flamand, Belgia, 1070
    - Hopital Erasme-Universite Libre de Bruxelles (ULB)
- Haine Saint PAUL
  - La Louviere, Haine Saint PAUL, Belgia, 7100
    - Centre hospitalier de Jolimont-Lobbes - Centre de Recherche Medicale de Jolimont
- Oost-vlaanderen
  - Aalst, Oost-vlaanderen, Belgia, 9300
    - Algemeen Stedelijk Ziekenhuis
  - Dendermonde, Oost-vlaanderen, Belgia, 9200
    - AZ Sint Blasius
  - Gent, Oost-vlaanderen, Belgia, 9000
    - AZ Sint Lucas Gent-Campus Sint Lucas
  - Ronse, Oost-vlaanderen, Belgia, 9600
    - AZ Glorieux
- West-vlaanderen
  - Kortrijk, West-vlaanderen, Belgia, 8500
    - AZ Groeninge-Campus Loofstraat
  - Oostende, West-vlaanderen, Belgia, 8400
    - AZ Damiaan
  - Veurne, West-vlaanderen, Belgia, 8630
    - A.Z. Sint-Augustinus Veurne
Brasil
- - Sao Paulo, Brasil, 01244-030
    - CPClin- Centro de Pesquisas Clinicas Ltda./Clinica Dr. Freddy Goldberg Eliaschewitz
  - Sao Paulo, Brasil, 01327-010
    - FGM-Clinica Paulista de Doencas Cardiovasculares
  - Sao Paulo, Brasil, 04024-900
    - SPDM Associacao Paulista para o Desenvolvimento da Medicina
  - Sao Paulo, Brasil, 04040-001
    - UNIFESP - Hospital Sao Paulo - Setor de Lipides, Aterosclerose e Biologia Vascular
  - Sao Paulo, Brasil, 05017-000
    - Instituto Jaqueline Scholz Issa e Mario Issa de Cardiologia LTDA
- BA
  - Salvador, BA, Brasil, 41810-010
    - Fundacao Bahiana de Cardiologia
  - Salvador, BA, Brasil, 41810-011
    - HBA S/A ASSISTENCIA MEDICA E HOSPITALAR-Hospital da Bahia
- Bahia
  - Salvador, Bahia, Brasil, 40170-130
    - Instituto Cardiopulmonar da Bahia
- CE
  - Fortaleza, CE, Brasil, 60430-140
    - Centro de Pesquisas em Diabetes e Doencas Endocrino-Metabolicas Ltda
- Ceara
  - Fortaleza, Ceara, Brasil, 60430-370
    - Hospital Universitário Walter Cantídio
  - Fortaleza, Ceara, Brasil, 60840-285
    - Hospital de Messejana Dr Carlos Alberto Studart Gomes
- Distrito Federal
  - Brasilia, Distrito Federal, Brasil, 70658-700
    - Instituto de Cardiologia do Distrito Federal
- Espirito Santo
  - Vitoria, Espirito Santo, Brasil, 29055-450
    - CEDOES - Centro de Diagnostico e Pesquisa da Osteoporose do Espirito Santo
- GO
  - Goiania, GO, Brasil, 74223-130
    - Via Medica - Clinica Medica Integrada Ltda - Barroso e Sebba Ltda
- Goias
  - Goiania, Goias, Brasil, 74093-300
    - INGOH - Instituto Goiano de Oncologia e Hematologia
- MG
  - Belo Horizonte, MG, Brasil, 30110-934
    - Hospital Felicio Rocho
  - Belo Horizonte, MG, Brasil, 30110-921
    - Hospital Lifecenter / Lifecenter Sistema de Saude S.A
  - Belo Horizonte, MG, Brasil, 30140-073
    - Hospital Universitário Sao José / FELUMA - MG
- Minas Gerais
  - Belo Horizonte, Minas Gerais, Brasil, 30110-021
    - Liga Mineira de Ressuscitação Cardiopulmonar
  - Belo Horizonte, Minas Gerais, Brasil, 30140-062
    - Hospital Vera Cruz
  - Belo Horizonte, Minas Gerais, Brasil, 30140-073
    - Hospital Universitario Ciencias Medicas / Fundacao Educacional Lucas Machado
  - Belo Horizonte, Minas Gerais, Brasil, 30150-320
    - Liga Mineira de Ressucitacao cardiopulmonar
  - Belo Horizonte, Minas Gerais, Brasil, 30150240
    - CARDSEARCH/CARDRESEARCH - Cardiologia Assistencial e de Pesquisa LTDA
  - Uberlandia, Minas Gerais, Brasil, 38405-320
    - Universidade Federal de Uberlândia
  - Uberlandia, Minas Gerais, Brasil, 38411-186
    - Eurolatino Pesquisas Medicas Ltda
- PA
  - Belem, PA, Brasil, 66073-000
    - Universidade Federal do Para - Hospital Universitario Joao de Barros Barreto
- PE
  - Recife, PE, Brasil, 52020-010
    - Centro de Pesquisas Médicas Básica e Clínica Ltda
- PR
  - Campina Grande do Sul, PR, Brasil, 83430-000
    - Sociedade Hospitalar Angelina Caron/Hospital e Maternidade Angelina Caron
  - Curitiba, PR, Brasil, 80010-100
    - Irmandade da Santa Casa de Misericordia de Curitiba - Hospital Santa Casa de Misericordia
  - Curitiba, PR, Brasil, 80045-170
    - Quanta Diagnostico e Terapia / Medicina Nuclear Alto da XV
- Parana
  - Curitiba, Parana, Brasil, 80010-030
    - Hospital Santa Casa de Curitiba
  - Curitiba, Parana, Brasil, 80730-150
    - Nucleo de Pesquisa Clinica
  - Maringa, Parana, Brasil, 87015-000
    - Hospital Parana - Parana Medical Research Center - MARIMED SERVICOS MEDICOS S.A.
- Pernambuco
  - Recife, Pernambuco, Brasil, 52051-380
    - Hospital Agamenon Magalhães
- RIO Grande DO SUL
  - Canoas, RIO Grande DO SUL, Brasil, 92425-055
    - Hospital Universitario - Associacao Educadora Sao Carlos - AESC
  - Pelotas, RIO Grande DO SUL, Brasil, 96015-290
    - Santa Casa de Misericordia de Pelotas
  - Porto Alegre, RIO Grande DO SUL, Brasil, 90035-903
    - Hospital de Clínicas de Porto Alegre
  - Porto Alegre, RIO Grande DO SUL, Brasil, 90110-270
    - Hospital Mae de Deus/Associacao Educadora Sao Carlos AESC/IMV - Instituto de Medicina Vascular
- RJ
  - Rio De Janeiro, RJ, Brasil, 22271-100
    - CCBR - Centro de Pesquisas e Analises Clinicas LTDA
  - Rio de Janeiro, RJ, Brasil, 22271-100
    - CCBR Brasil - Centro de Pesquisa e Analises Clinicas LTDA
- RN
  - Natal, RN, Brasil, 59020-035
    - Hemocardio S/S Ltda
- RS
  - Passo Fundo, RS, Brasil, 99010-080
    - Associacao Hospitalar Beneficente Sao Vicente de Paulo - Hospital Sao Vicente de Paulo
  - Porto Alegre, RS, Brasil, 90020-090
    - Irmandade Da Santa Casa de Misericordia de Porto Alegre - ISCMPA
  - Porto Alegre, RS, Brasil, 90610-000
    - Uniao Brasileira de Educacao e Assistencia (UBEA) - Hospital Sao Lucas da PUCRS
- SAO Paulo
  - Campinas, SAO Paulo, Brasil, 13010-001
    - Loema Medicina e Bem Estar- Centro Especializado em Cardiologia Ltda
  - Campinas, SAO Paulo, Brasil, 13020-431
    - Scentryphar Pesquisa Clinica
  - Campinas, SAO Paulo, Brasil, 13060-904
    - Hospital E Maternidade Celso Pierro PUC - Campinas - Sociedade Campineira de Educacao e Instrucao
  - Marilia, SAO Paulo, Brasil, 17515-000
    - ICM - Instituto do Coração de Marília
  - Paraiso, SAO Paulo, Brasil, 04005-004
    - Instituto Conceive
  - Santo Andre, SAO Paulo, Brasil, 09190-615
    - Hospital Estadual Mario Covas
  - Sao Jose Do Rio Preto, SAO Paulo, Brasil, 15015-750
    - Instituto Domingo Braile _ Braile Hospital Dia LTDA
  - Sao Jose do Rio Preto, SAO Paulo, Brasil, 15015210
    - IMC - Instituto de Molestias Cardiovasculares/Equipamentos Cardiovasculares Rio Preto Ltda
  - Sao Jose do Rio Preto, SAO Paulo, Brasil, 15090-000
    - Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto
  - Votuporanga, SAO Paulo, Brasil, 15500-003
    - Santa Casa de Misericórdia de Votuporanga
- SP
  - Campinas, SP, Brasil, 13087-567
    - CAEP - Centro Avancado de Estudos e Pesquisas Ltda.
  - Sao Paulo, SP, Brasil, 01228-000
    - CPQuali Pesquisa Clinica Ltda
  - Sao Paulo, SP, Brasil, 01232-010
    - Hospital Samaritano
  - Sao Paulo, SP, Brasil, 01233-000
    - Instituto de Conhecimento, Ensino e Pesquisa (Administrative local)
  - Sao Paulo, SP, Brasil, 01407-200
    - Comed Care Empresa de Atendimento Clinico Geral - LTDA - Hospital Total Care
  - Sao Paulo, SP, Brasil, 04062-001
    - CCBR Sao Paulo
  - Sao Paulo, SP, Brasil, 04266-010
    - CEPIC - Centro Paulista de Investigação Clínica e Serviços Médicos Ltda.
- Santa Catarina
  - Blumenau, Santa Catarina, Brasil, 89010-906
    - Hospital Santa Isabel
  - Sao Jose, Santa Catarina, Brasil, 88103-450
    - Insituto de Cardiologia de Santa Catarina
Canada
- - Quebec, Canada, G1V 4W2
    - Clinique des maladies lipidiques de Quebec
  - Quebec, Canada, G1G 3Y8
    - Recherche Clinique Sigma inc
- Alberta
  - Calgary, Alberta, Canada, T2H 2G4
    - LMC Diabetes & Endocrinology (Calgary)
  - Calgary, Alberta, Canada, T2N 4Z6
    - Foothills Hospital/University of Calgary
  - Calgary, Alberta, Canada, T2V 4J2
    - Nanji Professional Corporation
- British Columbia
  - Kelowna, British Columbia, Canada, V1Y 1V6
    - The Medical Arts Health Research Group
  - Surrey, British Columbia, Canada, V3V 0C6
    - SMH Cardiology Clinical Trials
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr Stephen Pearce Inc
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Adam Yeung Inc.
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Micheal Kanakos Inc
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Raymond Dong Inc.
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Richard Bon Inc.
  - Surrey, British Columbia, Canada, V3V 0C6
    - Dr. Stephen S. Cheung Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr Peter K.H. Tan Inc
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Dante E. Manyari Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - Dr. Stephanie Au, Inc.
  - Surrey, British Columbia, Canada, V3V 1N1
    - SMH Cardiology Clinical Trials Inc.
  - Surrey, British Columbia, Canada, V3W 3C3
    - Dr. Kapil M. Bhagirath Medical Services Corporation
  - Victoria, British Columbia, Canada, V8R 4R2
    - Victoria Heart Institute Foundation
  - Victoria, British Columbia, Canada, V8T 5G4
    - Discovery Clinical Services Ltd.
- Manitoba
  - Winnipeg, Manitoba, Canada, R2H 2A6
    - St. Boniface Hospital
  - Winnipeg, Manitoba, Canada, R2V 3P4
    - Unicity Laboratory Services
  - Winnipeg, Manitoba, Canada, R2V 4W3
    - Rivergrove Medical Clinic
- New Brunswick
  - Moncton, New Brunswick, Canada, E1G 1A7
    - G.A. Research Associates Ltd.
  - Saint John, New Brunswick, Canada, E2L 4L2
    - Cardiology Research Associates of New Brunswick
- Newfoundland and Labrador
  - St. John's, Newfoundland and Labrador, Canada, A1B 3V6
    - Health Sciences Centre
- Ontario
  - Brampton, Ontario, Canada, L6S 0C9
    - LMC Diabetes & Endocrinology (Brampton)
  - Burlington, Ontario, Canada, L7M 4Y1
    - JBN Medical Diagnostic Services Inc.
  - Burlington, Ontario, Canada, L7M 4Y1
    - Aviva Clinical Trial Group Inc.
  - Burlington, Ontario, Canada, L7R 4E2
    - Philippe R. Beaudry Medicine Professional Corporation
  - Cambridge, Ontario, Canada, N1R 6V6
    - Cambridge Cardiac Care Centre
  - Cambridge, Ontario, Canada, N1R 7R1
    - Vizel Cardiac Research, Saul Vizel Professional Medicine Corporation
  - Collingwood, Ontario, Canada, L9Y 1W3
    - Moran Medical Centre
  - Fort Erie, Ontario, Canada, L2A 1Z3
    - C & L Research
  - Hamilton, Ontario, Canada, L8K 3P3
    - Parkdale Medical Centre
  - London, Ontario, Canada, N6G 2M1
    - Western University - WCPHFM
  - London, Ontario, Canada, N6G 2V4
    - Stroke Prevention & Atherosclerosis Research Centre (SPARC)-Siebens-Drake Research Institute
  - Markham, Ontario, Canada, L6B 0P9
    - LMC Diabetes & Endocrinology (Markham)
  - Newmarket, Ontario, Canada, L3Y 8C3
    - Newmarket Cardiology Research Group
  - Oakville, Ontario, Canada, L6M 1M1
    - LMC Clinical Research Inc. (Oakville)
  - Oakville, Ontario, Canada, L6M 1M1
    - LMC Oakville
  - Oshawa, Ontario, Canada, L1J 2K1
    - The Office of Dr. James Cha
  - Peterborough, Ontario, Canada, K9J 0B2
    - Kawartha Cardiology Clinical Trials
  - Sarnia, Ontario, Canada, N7T 4X3
    - London Road Diagnostic Clinic and Medical Centre
  - Sarnia, Ontario, Canada, N7T 4X3
    - Sarnia Institute of Clinical Research
  - Scarborough, Ontario, Canada, M1E 5E9
    - Scarborough Cardiology Research Associates Inc.
  - Smiths Falls, Ontario, Canada, K7A 4W8
    - Canadian Centre for Research on Diabetes
  - Sudbury, Ontario, Canada, P3E 2N8
    - Brian Y.L. Wong Medicine Professional Corporation
  - Thornhill, Ontario, Canada, L4J 8L7
    - Lmc Diabetes & Endocrinology (Thornhill)
  - Toronto, Ontario, Canada, M9V 4B4
    - Dr. Anil K. Gupta Medicine Professional Corporation
  - Toronto, Ontario, Canada, M3J 2C5
    - Canadian Phase Onward, Inc.
  - Toronto, Ontario, Canada, M3J 1N2
    - JJ Dig Research Ltd
  - Toronto, Ontario, Canada, M4G 3E8
    - Lmc Diabetes & Endocrinology (Bayview)
  - Waterloo, Ontario, Canada, N2T 0C1
    - Dr. Mohan Babapulle Medicine Professional Corporation
  - Weston, Ontario, Canada, M9N 1W4
    - Dr. Louis Yao
- Quebec
  - Chicoutimi, Quebec, Canada, G7H 7K9
    - Ecogene-21
  - Chicoutimi, Quebec, Canada, G7H 7Y8
    - Q & T Research Chicoutimi
  - Gatineau, Quebec, Canada, J8Y 6S8
    - Q&T Recherche Outaouais Inc.
  - Laval, Quebec, Canada, H7T 2P5
    - Centre de Recherche Clinique de Laval
  - Mirabel, Quebec, Canada, J7J 2K8
    - Omnispec clinical research inc
  - Montreal, Quebec, Canada, H1T 1C8
    - Montreal Heart Institute
  - Montreal, Quebec, Canada, H2Y 1S1
    - Diex Research Montreal, Inc.
  - Sherbrooke, Quebec, Canada, J1G 2E8
    - Centre Hospitalier Universitaire de Sherbrooke- Hotel-Dieu
  - St Charles-Borromee, Quebec, Canada, J6E 6J2
    - Centre integre de sante et de services sociaux de Lanaudiere (CISSSL)
  - St-Georges, Beauce, Quebec, Canada, G5Y 4T8
    - Centre intégré de Santé et de Services Sociaux de Chaudière-Appalaches (CISSS-CA)
  - St-Jerome, Quebec, Canada, J7Z 5T3
    - CISSS des Laurentides-Point de Service de St-Jerome- Comite d'ethique de la recherche
  - St-Jerome, Quebec, Canada, J7Z 5T3
    - St-Jerome Medical Research Inc.
  - Ville Saint-Laurent, Quebec, Canada, H4T 1Z9
    - LMC Diabetes & Endocrinology (Montreal)
Chile
- - Puerto Varas, Chile, 5550170
    - Quantum Research
- Metropolitana
  - Providencia Santiago, Metropolitana, Chile, 7500710
    - Biomedica Research Group
  - Santiago, Metropolitana, Chile, 7500021
    - CICAB
  - Santiago, Metropolitana, Chile, 7500739
    - SMOLAM
  - Santiago, Metropolitana, Chile, 8053095
    - Hopsital y CRS El Pino
  - Santiago, Metropolitana, Chile, 8207257
    - Complejo Asitencial Dr. Sotero del Rio
- Region DE LA Araucania
  - Temuco, Region DE LA Araucania, Chile, 4781156
    - Centro de Investigacion Clinica del Sur
- Region DE LOS Lagos
  - Osorno, Region DE LOS Lagos, Chile, 5311092
    - Corporacion de Beneficencia Osorno
- Region DE Magallanes
  - Punta Arenas, Region DE Magallanes, Chile, 6210005
    - Hospital Clinico Magallanes
- Region Metropolitana
  - Santiago, Region Metropolitana, Chile, 7500710
    - Servicios Medicos Godoy
Colombia
- Antioquia
  - Medellin, Antioquia, Colombia, 00000
    - Hospital Pablo Tobon Uribe
  - Medellin, Antioquia, Colombia
    - Centro de Investigacion Clinica Avanzada y Multidisciplinaria CICLAM
  - Medellin, Antioquia, Colombia
    - Centro de Medicina del Ejercicio y Rehabilitacion Cardiac - CEMDE S.A.
  - Medellin, Antioquia, Colombia
    - Rodrigo Botero S.A.S.
- Atlantico
  - Barranquilla, Atlantico, Colombia, 080020
    - Clinica de la Costa Ltda
  - Barranquilla, Atlantico, Colombia, 80020
    - Centro Cientifico Asistencial Jose Luis Accini S.A.S.
  - Barranquilla, Atlantico, Colombia
    - Corazon Ips Sas.
  - Barranquilla, Atlantico, Colombia
    - Fundacion del Caribe para la Investigacion Biomedica - Fundacion BIOS
- Bolivar
  - Cartagena, Bolivar, Colombia
    - Centro de Diagnostico Cardiologico LTDA.
- Caldas
  - Manizales, Caldas, Colombia
    - Asociacion IPS Medicos Internistas de Caldas
- Cundinamarca
  - Bogota D C, Cundinamarca, Colombia, 00
    - Hospital Universitario San Ignacio
  - Bogota D.C, Cundinamarca, Colombia, 110221
    - Dexadiab Servicios Medicos LTDA
  - Bogota D.C, Cundinamarca, Colombia, 111211
    - Caja de Compensacion Familiar CAFAM, Sede Centro de Atencion en Salud CAFAM FLORESTA
  - Bogota D.C., Cundinamarca, Colombia, 110911
    - Medplus Medicina Prepagada S.A.
  - Bogota D.C., Cundinamarca, Colombia
    - Instituto de Investigacion Endocrinologia y Prevencion Metabolica - ENDOCARE LTDA.
  - Bogota D.C., Cundinamarca, Colombia
    - Simedics Ips Sas
  - Bogota D.C., Cundinamarca, Colombia
    - Solano & Terront Servicios Medicos Ltda-Establecimiento Comercial UNIENDO
  - Zipaquira, Cundinamarca, Colombia, 250252
    - Healthy Medical Center S.A.S
- Narino
  - Pasto, Narino, Colombia
    - Fundación Centro de Obesidad y Metabolismo COMETA
- Santander
  - Bucaramanga, Santander, Colombia
    - Instituto del Corazon de Bucaramanga S.A.
  - Floridablanca, Santander, Colombia
    - Fundación Cardiovascular de Colombia - Instituto del Corazón Floridablanca
  - Floridablanca, Santander, Colombia, 681004
    - Fundación Cardiovascular de Colombia - Instituto del Corazón Floridablanca
- Valle DEL Cauca
  - Cali, Valle DEL Cauca, Colombia, 760001
    - Fundación Reina Isabel
Danmark
- - Aabenraa, Danmark, 6200
    - Aabenraa Hospital Hjertemedicinsk klinik Kredslobscentret, SHS
  - Aabenraa, Danmark, 6200
    - Sygehus Sonderjylland Aabenraa
  - Aalborg, Danmark, 9000
    - Aalborg Universitetshospital, Lipidklinikken
  - Aalborg, Danmark, 9000
    - CCBR Aalborg
  - Aarhus, Danmark, 8200
    - Aarhus Universitetshospital Skejby, Hjertesygdomme ¿ Klinisk Forskning
  - Ballerup, Danmark, DK - 2750
    - CCBR Ballerup
  - Copenhagen NV, Danmark, 2400
    - Bispebjerg og Frederiksberg Hospital
  - Esbjerg, Danmark, 6700
    - Sydvestjysk Sygehus, Hjertemedicinsk Projektgruppe
  - Frederiksberg, Danmark, 2000
    - Frederiksberg Hospital
  - Glostrup, Danmark, 2600
    - Glostrup Hospital
  - Herlev, Danmark, 2730
    - Herlev Universitetshospital
  - Herning, Danmark, 7400
    - Regionshospitalet Herning
  - Hillerod, Danmark, 3400
    - Hillerod Hospital
  - Hvidovre, Danmark, 2650
    - Hvidovre Universitetshospital
  - Kobenhavn O, Danmark, 2100
    - Karkirurgisk Klinisk
  - Kobenhavn S., Danmark, 2300
    - Amager Hospital
  - Koege, Danmark, 4600
    - Region Sjaelland Sygehus Nord, Koge Sygehus
  - Kolding, Danmark, 6000
    - Kolding Sygehus
  - Naestved, Danmark, 4700
    - Region Sjaelland Naestved Sygehus
  - Nykobing F., Danmark, 4800
    - Nykobing F. Sygehus-Medicinsk afdeling
  - Randers, Danmark, 8930
    - Regionshospitalet Randers
  - Silkeborg, Danmark, 8600
    - Regionshospitalet Silkeborg, Hjerte Projektkontor
  - Slagelse, Danmark, 4200
    - Slagelse Sygehus
  - Svendborg, Danmark, 5700
    - Svendborg Sygehus
  - Vejle, Danmark, DK 7100
    - CCBR Vejle
  - Viborg, Danmark, 8800
    - Hospitalsenheden Midt, Regionshospital Viborg
Den russiske føderasjonen
- - Chelyabinsk, Den russiske føderasjonen, 454047
    - Municipal Budgetary State Healthcare Institution "City Clinical Hospital #6"
  - Chelyabinsk, Den russiske føderasjonen, 454092
    - Non-State Institution of Healthcare "Railway Clinical Hospital at station Chelyabinsk of open
  - Chelyabinsk, Den russiske føderasjonen, 454136
    - State Budgetary Healthcare Institution "Region Clinical Hospital #3"
  - Ekaterinburg, Den russiske føderasjonen, 620039
    - Municipal Autonomous Institution "City Clinical Hospital #14"
  - Ivanovo, Den russiske føderasjonen, 153012
    - Regional Budgetary Healthcare Institution "Cardiology Dispensary"
  - Kaluga, Den russiske føderasjonen, 428007
    - State Budgetary Institution of Healthcare of Kaluga Region "Kaluga Regional Hospital"
  - Kazan, Den russiske føderasjonen, 420012
    - Federal State Budgetary Educational Institution of Higher Education "Kazan State Medical University"
  - Kazan, Den russiske føderasjonen, 420064
    - State Autonomous Healthcare Institution
  - Kemerovo, Den russiske føderasjonen, 650000
    - "SAHI of Kemerovo ""Regional Clinical Hospital of Emergency Medical Care n.a. M.A Podgorbunsky """
  - Kemerovo, Den russiske føderasjonen, 650000
    - Municipal Budgetary Institution of Healthcare
  - Kemerovo, Den russiske føderasjonen, 650002
    - Federal state budgetary institution Research institute of complex problems
  - Kemerovo, Den russiske føderasjonen, 650099
    - FSHI "Medical and Sanitary Unit of the Ministry of Internal Affairs of Russia across Kemerovo region
  - Kirov, Den russiske føderasjonen, 610014
    - Kirov Regional State Budgetary Healthcare Institution "Kirov City Clinical Hospital #1"
  - Kursk, Den russiske føderasjonen, 305035
    - Regional Budgetary Healthcare Institution "Kursk City Clinical Emergency Hospital"
  - Moscow, Den russiske føderasjonen, 109388
    - Non-State Institution of Healthcare "Central Clinical Hospital #6 OAO "RZhD"
  - Moscow, Den russiske føderasjonen, 109990
    - Federal State Budgetary Institution "State Research Center for Preventive Medicine" of the Ministry
  - Moscow, Den russiske føderasjonen, 111539
    - SBHI of Moscow city "City Clinical Hospital #15 n.a. O.M. Filatova"
  - Moscow, Den russiske føderasjonen, 119435
    - SBEI of HPE I. M. Sechenov First Moscow State Medical University, UKB #2
  - Moscow, Den russiske føderasjonen, 121309
    - State Healthcare Institution "City Clinical Hospital #51 of Healthcare Department of Moscow City"
  - Moscow, Den russiske føderasjonen, 121359
    - Federal State Budgetary Institution "Central Clinical Hospital with Polyclinic"
  - Moscow, Den russiske føderasjonen, 121552
    - Federal State Budgetary Institution "Russian Cardiology Research And Production Complex" Of Ministry
  - Moscow, Den russiske føderasjonen, 121552
    - Russian Cardiology Research And Production Complex of Ministry of Health of Russian Federation
  - Moscow, Den russiske føderasjonen, 125284
    - Moscow State Healthcare Institution "City clinical hospital n.a. S.P.Botkin"
  - Moscow, Den russiske føderasjonen, 127644
    - SBIH "City Clinical Hospital #81 Departments of Healthcare of Moscow"
  - Moscow, Den russiske føderasjonen, 129090
    - Federal State Budget Institution "Out-patient Clinic #3" of Russian Federation,
  - Murmansk, Den russiske føderasjonen, 183047
    - State Regional Budgetary Healthcare Institution
  - Nizhniy Novgorod, Den russiske føderasjonen, 603076
    - State Budgetary Healthcare Institution of Nizhegorodskaya Region
  - Novosibirsk, Den russiske føderasjonen, 630089
    - Federal State Budgetary Institution "Research Institute of Therapy and Preventive Medicine" of
  - Novosibirsk, Den russiske føderasjonen, 630091
    - SBRIHPE "Novosibirsk State Medical University" of MHSD of RF
  - Novosibirsk, Den russiske føderasjonen, 630099
    - "Reafan" LLC
  - Novosibirsk, Den russiske føderasjonen, 630102
    - "SBHI of Novosibirsk ""City Clinical Hospital of Emergency Medical Care # 2"""
  - Novosibirsk, Den russiske føderasjonen, 630102
    - Municipal Budgetary Institution of Healthcare of Novosibirsk
  - Novosibirsk, Den russiske føderasjonen, 630102
    - State Budgetary Institution of Healthcare of Novosibirsk region City Clinical Hospital of Emergency
  - Penza, Den russiske føderasjonen, 440026
    - State Budgetary Institution of Healthcare"Penzenskaya Regional clinical hospital n.a N.N Burdenko"
  - Pushkin, Den russiske føderasjonen, 196601
    - SBHI of Saint-Petersburg "City Hospital # 38 n.a. N.A. Semashko"
  - Rostov-on-Don, Den russiske føderasjonen, 344022
    - Federal State Budgetary Educational Institution of Higher Education
  - Rostov-on-Don, Den russiske føderasjonen, 344022
    - State Budgetary Educational Institution of Higher Professional Education
  - Rostov-on-Don, Den russiske føderasjonen, 344068
    - State Budgetary Educational Institution of Higher Professional Education
  - Saint Petersburg, Den russiske føderasjonen, 197341
    - Federal State Budgetary Institution
  - Saint-Petersburg, Den russiske føderasjonen, 191186
    - Limited Liability Company International Medical Centre SOGAZ
  - Saint-Petersburg, Den russiske føderasjonen, 192148
    - Saint-Petersburg State Budgetary Institution of Healthcare "City Hospital #23"
  - Saint-Petersburg, Den russiske føderasjonen, 193312
    - Saint-Petersburg State Budgetary Healthcare Institution "City Alexandrovskaya Hospital"
  - Saint-Petersburg, Den russiske føderasjonen, 194017
    - Federal state budget institution of healthcare Saint-Petersburg clinical hospital of Russian Academy
  - Saint-Petersburg, Den russiske føderasjonen, 194354
    - Limited Liability Company "Reavita"
  - Saint-Petersburg, Den russiske føderasjonen, 196084
    - "Limited Liability Company ""Institute of Medical Research"""
  - Saint-Petersburg, Den russiske føderasjonen, 196084
    - Limited Liability Company "Institute of Medical Research"
  - Saint-Petersburg, Den russiske føderasjonen, 196084
    - LLC "Institution of medical studies"
  - Saint-Petersburg, Den russiske føderasjonen, 196601
    - City Hospital # 38 n.a. Semashko
  - Saint-Petersburg, Den russiske føderasjonen, 197022
    - SBEI of HPE "First Pavlov State Medical University of St. Petersburg" of the MoH of the RF
  - Saint-Petersburg, Den russiske føderasjonen, 197110
    - Federal State Budgetary Institution "Advisory Diagnostic Center and Polyclinic"
  - Saint-Petersburg, Den russiske føderasjonen, 198205
    - Saint-Petersburg State Budgetary Healthcare Institution "City Hospital #15"
  - Samara, Den russiske føderasjonen, 443070
    - State Budgetary Healthcare Institution "Samara Regional Clinical Cardiology Dispensary"
  - Saratov, Den russiske føderasjonen, 410039
    - MHI "City Clinical Hospital #12" of the Healthcare Committee
  - Saratov, Den russiske føderasjonen, 410053
    - State Institution of Healthcare "Regional Clinical Hospital"
  - Smolensk, Den russiske føderasjonen, 214019
    - State Budget Educational Institution of Higher Professional Education
  - St. Petersburg, Den russiske føderasjonen, 197022
    - Federal State Budgetary Educational Institution of Higher Education
  - Tomsk, Den russiske føderasjonen, 634009
    - Tyumen Cardiology Research Center-branch of the Tomsk NRMC
  - Tomsk, Den russiske føderasjonen, 634050
    - GBOU VPO Siberian State Medical University Ministry of Healthcare of the Russian Federation
  - Tomsk, Den russiske føderasjonen, 634050
    - State Budgetary Educational Institution of Highest Professional Education "Siberian State Medical
  - Tyumen, Den russiske føderasjonen, 625000
    - State Autonomous Institution of Healthcare of the Tyumen region Tyumen Institute of Therapy
  - Tyumen, Den russiske føderasjonen, 625026
    - Affiliate of the Federal State Budgetary Institution Scientific Research Institute of Cardiology
  - Yaroslavl, Den russiske føderasjonen, 150003
    - State Autonomous Healthcare Institution Of Yaroslavl Region
  - Yaroslavl, Den russiske føderasjonen, 150010
    - FSBEI of HE "Yaroslavl State Medical University" MH of the Russian Federation
  - Yaroslavl, Den russiske føderasjonen, 150023
    - State Budgetary Healthcare Institution of Yaroslavl Region "Clinical Hospital No. 10"
  - Yaroslavl, Den russiske føderasjonen, 150030
    - State Healthcare Institution of Yaroslavl Region "Clinical Hospital #8"
- Krasnodar Region
  - Krasnodar, Krasnodar Region, Den russiske føderasjonen, 350086
    - State Budgetary Healthcare Institution "Research Institution - Regional Clinical Hospital #1
- Moscow Region
  - Lubertsy, Moscow Region, Den russiske føderasjonen, 140006
    - State Budgetary Healthcare Institution of Moscow Region "Lubertsy Regional Hospital #2"
  - Troitsk, Moscow Region, Den russiske føderasjonen, 142190
    - Federal State Budgetary Institution of Healthcare Hospital of Russian Academy of Sciences
- Ryazan Region
  - Ryazan, Ryazan Region, Den russiske føderasjonen, 390039
    - State Budgetary Institution "Ryazan Regional Clinical Hospital"
- Sestroretsk
  - Saint-Petersburg, Sestroretsk, Den russiske føderasjonen, 197706
    - Saint Petersburg State Budgetary Institution of Healthcare Municipal hospital
- Tatarstan Republic
  - Kazan, Tatarstan Republic, Den russiske føderasjonen, 420033
    - FSBEI of HE Kazan State Medical University on the base of SBHI Clinical Hospital No.2
  - Kazan, Tatarstan Republic, Den russiske føderasjonen, 420033
    - SBEI of HPE Kazan State Medical University on the base of SBHI Clinical Hospital No.2
Finland
- - Espoo, Finland, 02740
    - HYKS Jorvin sairaala
  - Hameenlinna, Finland, 13100
    - Linnan Klinikka Oy
  - Helsinki, Finland, 00290
    - Helsinki University Central Hospital
  - Helsinki, Finland, 00180
    - GERI-MED Oy
  - Helsinki, Finland, FI-00290
    - Helsingin yliopistollinen keskussairaala, Sisaetaudit ja kuntoutus, Biomedicum 2U
  - Joensuu, Finland, 80100
    - Ita-Suomen laakarikeskus Oy
  - Jyvaskyla, Finland, 40620
    - StudyCor Oy
  - Kerava, Finland, 04200
    - Laeaekaerikeskus Aava Kerava
  - Kinkomaa, Finland, 40930
    - Menoa oy
  - Kokkola, Finland, 67200
    - Kokkolan Keskussairaala
  - Kotka, Finland, 48600
    - Mewell liikuntaklinikka
  - Kuopio, Finland, 70100
    - Itae-Suomen Laeaekaeritalo
  - Kuopio, Finland, 70100
    - Terveystalo Kuopio
  - Oulu, Finland, 90220
    - Oulu University Hospital
  - Oulu, Finland, 90100
    - Oulu Mentalcare Oy
  - Oulu, Finland, 90100
    - Terveystalo Oulu, Diapolis
  - Pori, Finland, 28100
    - Porin Lääkäritalo Oy
  - Siilinjarvi, Finland, 71800
    - Terveystalo Siilinjarvi
  - Tampere, Finland, 33520
    - FinnMedi Oy
  - Turku, Finland, 20520
    - Turku University Hospital
  - Turku, Finland, 20100
    - Terveystalo Pulssi
  - Vantaa, Finland, 01600
    - Vantaan Tutkimuskeskus
  - Ylitornio, Finland, 95600
    - Ylitornion Terveyskeskus
Forente stater
- Alabama
  - Athens, Alabama, Forente stater, 35611
    - North Alabama Research Center LLC
  - Athens, Alabama, Forente stater, 35611
    - Ernest Hendrix, MD, PC
  - Birmingham, Alabama, Forente stater, 35294
    - University of Alabama at Birmingham
  - Birmingham, Alabama, Forente stater, 35211
    - Clinical Research Advantage, Inc./Simon Williamson Clinic
  - Birmingham, Alabama, Forente stater, 35209
    - Central Alabama Research
  - Birmingham, Alabama, Forente stater, 35235
    - Birmingham Heart Clinic, P.C.
  - Birmingham, Alabama, Forente stater, 35243
    - Cardiovascular Associates of the Southeast, LLC
  - Fort Payne, Alabama, Forente stater, 35967
    - Appalachian Cardiovascular Associates
  - Gulf Shores, Alabama, Forente stater, 36542
    - Fundamental Research, LLC
  - Guntersville, Alabama, Forente stater, 35976
    - Avant Research Associates, LLC
  - Hamilton, Alabama, Forente stater, 35570
    - Boyett Health Services
  - Huntsville, Alabama, Forente stater, 35801
    - Saadat Ansari Internal Medicine
  - Mobile, Alabama, Forente stater, 36608
    - CB Flock Research Corporation
- Alaska
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Heart Institute
- Arizona
  - Glendale, Arizona, Forente stater, 85306
    - Phoenix Heart, PLLC
  - Glendale, Arizona, Forente stater, 85308
    - Arrowhead Internal Medicine
  - Phoenix, Arizona, Forente stater, 85029
    - Redpoint Research
  - Phoenix, Arizona, Forente stater, 85018
    - Clinical Research Advantage, Inc./Family Practice Specialists, Ltd.
  - Sierra Vista, Arizona, Forente stater, 85635
    - Cochise Clinical Research
  - Tempe, Arizona, Forente stater, 85282
    - Clinical Research Advantage, Inc. (Administrative Mailing Only)
  - Tucson, Arizona, Forente stater, 85710
    - Southwest Heart Group
  - Tucson, Arizona, Forente stater, 85713
    - University of Arizona Medical Center South Campus
  - Tucson, Arizona, Forente stater, 85715
    - Arizona Endocrine and Rheumatology Associates
- Arkansas
  - Little Rock, Arkansas, Forente stater, 72211
    - Arkansas Heart Hospital Clinic
  - Little Rock, Arkansas, Forente stater, 72211
    - Arkansas Site Management Services, LLC
- California
  - Anaheim, California, Forente stater, 92801
    - Cardiology Consultants of Orange County Medical Group Inc.
  - Bakersfield, California, Forente stater, 93309
    - Premier Valley Medical Group
  - Beverly Hills, California, Forente stater, 90211
    - Westside Medical Associates of Los Angeles
  - Beverly Hills, California, Forente stater, 90210
    - Cardiovascular Research Foundation of Southern California
  - Buena Park, California, Forente stater, 90620
    - Southbay Pharma Research
  - Carmichael, California, Forente stater, 95608
    - Med Center
  - Cerritos, California, Forente stater, 90703
    - Pioneer Medical Group
  - Concord, California, Forente stater, 94520
    - John Muir Physician Network Clinical Research Center
  - Cudahy, California, Forente stater, 90201
    - Atlantic Ave Medical Clinic Inc.
  - Downey, California, Forente stater, 90241
    - Multani Medical Group
  - El Cajon, California, Forente stater, 92020
    - TriWest Research Associates, LLC
  - Encinitas, California, Forente stater, 92024
    - Diagnamics, Inc.
  - Encino, California, Forente stater, 91436
    - T. Joseph Raoof, Md, Inc/Encino Research Center
  - Escondido, California, Forente stater, 92025
    - AVIVA Research
  - Fair Oaks, California, Forente stater, 95628
    - Med Investigations, Inc.
  - Fresno, California, Forente stater, 93720
    - Valley Research
  - Fullerton, California, Forente stater, 92835
    - St. Jude Hospital Yorba Linda dba St. Joseph Heritage Healthcare
  - La Palma, California, Forente stater, 90623
    - Omnibus Clinical Research
  - Laguna Hills, California, Forente stater, 92653
    - Alliance Research Centers
  - Laguna Hills, California, Forente stater, 92653
    - Prime Care Clinical Research Center
  - Lincoln, California, Forente stater, 95648
    - Clinical Trials Research
  - Long Beach, California, Forente stater, 90806
    - Long Beach Memorial Medical Center
  - Los Angeles, California, Forente stater, 90022
    - Academic Medical Research Institute
  - Los Angeles, California, Forente stater, 90017
    - American Institute of Research
  - Los Angeles, California, Forente stater, 90017
    - Intermed Group
  - Los Angeles, California, Forente stater, 90022
    - Eastside Clinical Research Associates
  - Los Gatos, California, Forente stater, 95032
    - Richard S. Cherlin, MD
  - Mission Hills, California, Forente stater, 91345
    - Facey Medical Foundation
  - Northridge, California, Forente stater, 91325
    - Valley Clinical Trials, Inc.
  - Northridge, California, Forente stater, 91324
    - California Medical Research Associates Inc.
  - Orange, California, Forente stater, 92868
    - Diabetes Associates Medical Group
  - Port Hueneme, California, Forente stater, 93041
    - Saviers Medical Group
  - Poway, California, Forente stater, 92064
    - Arch Health Partners
  - Redondo Beach, California, Forente stater, 90277
    - A. R. I. Clinical Trials, Inc.
  - San Diego, California, Forente stater, 92103-6204
    - California Research Foundation
  - San Diego, California, Forente stater, 92111
    - San Diego Family Care dba Linda Vista Health Center
  - San Diego, California, Forente stater, 92111
    - San Diego Family Care
  - San Diego, California, Forente stater, 92117
    - Ritchken & First Md's
  - San Diego, California, Forente stater, 92120
    - Wetlin Research Associates, Inc.
  - San Ramon, California, Forente stater, 94582
    - West Coast Research LLC
  - Santa Ana, California, Forente stater, 92705
    - Syrentis Clinical Research
  - Santa Monica, California, Forente stater, 90404
    - Coastal Biomedical Research, Inc.
  - Spring Valley, California, Forente stater, 91978
    - Encompass Clinical Research
  - Stockton, California, Forente stater, 95204
    - St. Joseph's Medical Associates
  - Thousand Oaks, California, Forente stater, 91360
    - Westlake Medical Research
  - Torrance, California, Forente stater, 90502
    - Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
  - Torrance, California, Forente stater, 90509
    - Harbor - UCLA Medical Center
  - Torrance, California, Forente stater, 90502
    - Los Angeles Biomedical Research Institute at Harbor - UCLA Medical Center
  - Tustin, California, Forente stater, 92780
    - Orange County Research Center
  - Valley Village, California, Forente stater, 91607
    - Bayview Research Group
  - Ventura, California, Forente stater, 93003
    - Ventura Clinical Trials
  - Ventura, California, Forente stater, 93003
    - Coastal Metabolic Research Centre
  - Vista, California, Forente stater, 92083
    - Clinical Research Advantage, Inc. / Cassidy Medical Group - Vista
  - Westminster, California, Forente stater, 92683
    - Allianz Research Institute
  - Whittier, California, Forente stater, 90603
    - American Institute of Research Studies
  - Wildomar, California, Forente stater, 92595
    - Elite Clinical Trials, Inc.
  - Wildomar, California, Forente stater, 92595
    - Elite Clinical Trials, Incorporated
- Colorado
  - Colorado Springs, Colorado, Forente stater, 80909
    - Lynn Institute of the Rockies
  - Colorado Springs, Colorado, Forente stater, 80906
    - Colorado Springs Health Partners
  - Colorado Springs, Colorado, Forente stater, 80909
    - Expresscare Clinical Research
  - Colorado Springs, Colorado, Forente stater, 80909
    - Memorial Hospital: University of Colorado Health
  - Denver, Colorado, Forente stater, 80246
    - Lynn Institute of Denver
  - Glenwood Springs, Colorado, Forente stater, 81601
    - Western Colorado Research, LLC
  - Littleton, Colorado, Forente stater, 80120
    - South Denver Cardiology Associates, PC
- Connecticut
  - Bridgeport, Connecticut, Forente stater, 06610
    - Bridgeport Hospital
  - Bridgeport, Connecticut, Forente stater, 06606
    - Connecticut Clinical Research, Llc
  - Hartford, Connecticut, Forente stater, 06102
    - Hartford Hospital
  - Stamford, Connecticut, Forente stater, 06905
    - Stamford Therapeutics Consortium
  - Stamford, Connecticut, Forente stater, 06905
    - Cardiology Associates of Fairfield County, PC
- Delaware
  - Newark, Delaware, Forente stater, 19713
    - Christiana Care Health Services, Inc.
  - Wilmington, Delaware, Forente stater, 19803
    - Alfieri Cardiology
- District of Columbia
  - Washington, District of Columbia, Forente stater, 20036
    - Capital Medical Associates, PC
- Florida
  - Atlantis, Florida, Forente stater, 33462
    - ACRC - Cardiology
  - Brooksville, Florida, Forente stater, 34601
    - Meridien Research
  - Clearwater, Florida, Forente stater, 33756
    - Gulf Coast Endocrine and Diabetes Center
  - Coral Gables, Florida, Forente stater, 33134
    - Team Medical Research
  - Daytona Beach, Florida, Forente stater, 32117
    - Cardiology Associates Research Company
  - Daytona Beach, Florida, Forente stater, 32114
    - The Heart Group, PA
  - Delray Beach, Florida, Forente stater, 33484
    - Seidman Clinical Trials
  - Delray Beach, Florida, Forente stater, 33484
    - The Cardiology Center
  - Doral, Florida, Forente stater, 33166
    - Integrity Clinical Research, LLC
  - Doral, Florida, Forente stater, 33166
    - Moonshine Research Center, Inc.
  - Doral, Florida, Forente stater, 33166
    - Care Research Center Inc
  - Doral, Florida, Forente stater, 33126
    - Continental Research Corp
  - Doral, Florida, Forente stater, 33172
    - Advanced Clinical Research of Miami (ACROM) International
  - Fort Lauderdale, Florida, Forente stater, 33312
    - The Center for Diabetes and Endocrine Care
  - Fort Lauderdale, Florida, Forente stater, 33308
    - InvesClinic, LLC
  - Fort Lauderdale, Florida, Forente stater, 33308
    - The Office of Alan Graff, MD, PA
  - Fort Lauderdale, Florida, Forente stater, 33316
    - Broward Health Medical Center (BHMC) (Broward General Medical Center (BGMC))
  - Fort Lauderdale, Florida, Forente stater, 33316
    - The Office of Maxine E. Hamilton, MD, PA
  - Hialeah, Florida, Forente stater, 33010
    - State Of The Art Research, LLC
  - Hialeah, Florida, Forente stater, 33012
    - Direct Helpers Medical Center Inc
  - Hollywood, Florida, Forente stater, 33021
    - Research Physicians Network Alliance
  - Hollywood, Florida, Forente stater, 33024
    - Pines Clinical Research, Inc.
  - Jacksonville, Florida, Forente stater, 32205
    - Westside Center for Clinical Research
  - Jacksonville, Florida, Forente stater, 32216
    - Jacksonville Center for Clinical Research
  - Jacksonville, Florida, Forente stater, 32216
    - East Coast Institute for Research, LLC
  - Jacksonville, Florida, Forente stater, 32256
    - Solutions Through Advanced Research, Inc.
  - Jacksonville, Florida, Forente stater, 32204
    - East Coast Institute for Research, LLC
  - Jacksonville, Florida, Forente stater, 32207
    - River City Clinical Research
  - Jacksonville, Florida, Forente stater, 32223
    - Baker-Gilmore Cardiovascular Institute
  - Lakeland, Florida, Forente stater, 33805
    - Meridien Research
  - Largo, Florida, Forente stater, 33770
    - The Heart Institute at Largo
  - Margate, Florida, Forente stater, 33063
    - South Florida Clinical Research Institute
  - Melbourne, Florida, Forente stater, 32934
    - Accelovance
  - Miami, Florida, Forente stater, 33144
    - Medical Research Center
  - Miami, Florida, Forente stater, 33183
    - International Research Associates, LLC
  - Miami, Florida, Forente stater, 33147
    - Advanced Pharma Cr, Llc
  - Miami, Florida, Forente stater, 33126
    - Finlay Medical Research
  - Miami, Florida, Forente stater, 33126
    - Pharmax Research Clinic, Inc.
  - Miami, Florida, Forente stater, 33135
    - South Florida Research Center, Inc.
  - Miami, Florida, Forente stater, 33185
    - Kendall South Medical Center, Inc.
  - Miami, Florida, Forente stater, 33144
    - Nuren Medical & Research Center
  - Miami, Florida, Forente stater, 33186
    - Med Research of Florida, LLC
  - Miami, Florida, Forente stater, 33173
    - Research Institute of South Florida, Inc.
  - Miami, Florida, Forente stater, 33122
    - Future Clinical Research, Inc.
  - Miami, Florida, Forente stater, 33125
    - Advanced Clinical Research of Miami (ACROM) International
  - Miami, Florida, Forente stater, 33125
    - Project4Research, Inc
  - Miami, Florida, Forente stater, 33126
    - A & L Clinical research
  - Miami, Florida, Forente stater, 33142
    - Florida Medical Center & Research, Inc.
  - Miami, Florida, Forente stater, 33145
    - Doctors Research Institute
  - Miami, Florida, Forente stater, 33155
    - Coast Research Institute
  - Miami, Florida, Forente stater, 33155
    - My Community Research Center, Inc.
  - Miami, Florida, Forente stater, 33165
    - Columbus Clinical Services LLC
  - Miami, Florida, Forente stater, 33173
    - Cardiovascular Research Center of South Florida
  - Miami, Florida, Forente stater, 33174
    - A & O Research Center, Inc.
  - Miami, Florida, Forente stater, 33175
    - BWell Research Center
  - Miami, Florida, Forente stater, 33175
    - Pharmacology International Research, Inc.
  - Miami, Florida, Forente stater, 33176
    - Advanced Clinical Research
  - Miami, Florida, Forente stater, 33176
    - South Florida Research Group, LLC
  - Miami, Florida, Forente stater, 33185
    - M & M Medical Center, Inc
  - Miami Beach, Florida, Forente stater, 33140
    - Research Physicians Network Alliance
  - Miami Lakes, Florida, Forente stater, 33014
    - G & I Medical Research LLC
  - Naples, Florida, Forente stater, 34102
    - Southwest Florida Research
  - New Port Richey, Florida, Forente stater, 34653
    - BayCare Medical Group
  - New Port Richey, Florida, Forente stater, 34653
    - The Heart & Vascular Institute Of Florida
  - North Bay Village, Florida, Forente stater, 33141
    - Bravo Health Care Center
  - North Miami Beach, Florida, Forente stater, 33162
    - Harmony Clincal Research, Inc.
  - Orlando, Florida, Forente stater, 32803
    - Florida Hospital Cardiovascular Institute
  - Orlando, Florida, Forente stater, 32806
    - Omega Research Consultants, LLC
  - Ormond Beach, Florida, Forente stater, 32174
    - Millennium Research
  - Ormond Beach, Florida, Forente stater, 32174
    - Aba Family Medicine, LLC
  - Ormond Beach, Florida, Forente stater, 32174
    - Ribo Research, LLC dba Peninsula Research
  - Pembroke Pines, Florida, Forente stater, 33029
    - DBC Research USA
  - Pembroke Pines, Florida, Forente stater, 33027
    - South Broward Research
  - Pembroke Pines, Florida, Forente stater, 33024
    - A&R Research Group, LLC
  - Pembroke Pines, Florida, Forente stater, 33025
    - Research Physicians Network Alliance
  - Pembroke Pines, Florida, Forente stater, 33029
    - DBC Research
  - Pensacola, Florida, Forente stater, 32501
    - Cardiology Consultants
  - Pinellas Park, Florida, Forente stater, 33782
    - DMI Research, Inc.
  - Plant City, Florida, Forente stater, 33563
    - Clinical Research of Central Florida
  - Plant City, Florida, Forente stater, 33563
    - Clincal Research of Florida
  - Plantation, Florida, Forente stater, 33313-6066
    - Dr. Jeffrey Greiff MD, Office Of
  - Plantation, Florida, Forente stater, 33313
    - Nova Clinical Research Collaborative
  - Ponte Vedra, Florida, Forente stater, 32081
    - St. Johns Center for Clinical Research
  - Port Charlotte, Florida, Forente stater, 33952
    - Charlotte Heart Group Research Center
  - Saint Petersburg, Florida, Forente stater, 33709
    - Meridien Research
  - Saint Petersburg, Florida, Forente stater, 33713
    - Advance Medical Research
  - Sarasota, Florida, Forente stater, 34239
    - Cardiovascular Center of Sarasota
  - Sarasota, Florida, Forente stater, 34232
    - Intercoastal Medical Group
  - Sarasota, Florida, Forente stater, 34239
    - Heart & Vascular Center Research
  - Sarasota, Florida, Forente stater, 34239
    - Intercoastal Medical Group (Drug Shipment Address and Administrative)
  - Seminole, Florida, Forente stater, 33777
    - The Office of Bridget Bellingar, DO
  - Tamarac, Florida, Forente stater, 33319
    - Vita Health & Medical Center, Inc./Concept Clinical Trials, LLC
  - Trinity, Florida, Forente stater, 34655
    - Interventional Cardiac Consultants
  - Wellington, Florida, Forente stater, 33449
    - Cardiology Partners Clinical Research Institute
  - West Palm Beach, Florida, Forente stater, 33401
    - Metabolic Research Institute, Inc.
  - West Palm Beach, Florida, Forente stater, 33401
    - Cleveland Clinic Cardiology Associates
  - Winter Haven, Florida, Forente stater, 33880
    - Clinical Research of Central Florida
- Georgia
  - Atlanta, Georgia, Forente stater, 30322
    - Emory University Hospital
  - Atlanta, Georgia, Forente stater, 30318
    - Atlanta Diabetes Associates
  - Atlanta, Georgia, Forente stater, 30331
    - Atlanta Center for Medical Research
  - Columbus, Georgia, Forente stater, 31904
    - Columbus Regional Research Institute
  - Conyers, Georgia, Forente stater, 30094
    - Rockdale Medical Research Associates
  - Covington, Georgia, Forente stater, 30014
    - Georgia Heart Specialists, LLC
  - Decatur, Georgia, Forente stater, 30033
    - NeuroStudies.net, LLC
  - Dunwoody, Georgia, Forente stater, 30338
    - Alta Pharmaceutical Research Center
  - Norcross, Georgia, Forente stater, 30071
    - In-Quest Medical Research, LLC
  - Roswell, Georgia, Forente stater, 30075
    - Atlanta Center for Clinical Research / Internal Medicine
  - Snellville, Georgia, Forente stater, 30078
    - Georgia Clinical Research, LLC
  - Snellville, Georgia, Forente stater, 30039
    - Dr. B. Abraham, P.C.
  - Stockbridge, Georgia, Forente stater, 30281
    - Clinical Research Atlanta
- Hawaii
  - Honolulu, Hawaii, Forente stater, 96814
    - East-West Medical Research Institute
- Idaho
  - Blackfoot, Idaho, Forente stater, 83221
    - Elite Clinial Trials, LLLP
  - Blackfoot, Idaho, Forente stater, 83221
    - Elite Clinial Trials
  - Caldwell, Idaho, Forente stater, 83605
    - St. Luke's Idaho Cardiology Associates
  - Meridian, Idaho, Forente stater, 83646
    - Solaris Clinical Research
  - Nampa, Idaho, Forente stater, 83686-6011
    - Saltzer Medical Group, PA
- Illinois
  - Arlington Heights, Illinois, Forente stater, 60005
    - Northwest Heart Clinical Research, LLC
  - Chicago, Illinois, Forente stater, 60604
    - Clinical Research Advantage, Inc./Michigan Avenue Internists
  - Chicago, Illinois, Forente stater, 60616
    - Apex Medical Research, AMR, Inc.
  - Chicago, Illinois, Forente stater, 60631
    - Clinical Research Advantage, Inc./Medical and Procedural Specialists of Illinois
  - Evanston, Illinois, Forente stater, 60201
    - Evanston Premier Healthcare Research, LLC
  - Gurnee, Illinois, Forente stater, 60031
    - Clinical Investigation Specialists, Inc
  - Mokena, Illinois, Forente stater, 60448
    - Heart Care Centers of Illinois
  - Rock Island, Illinois, Forente stater, 61201
    - Advanced Cardiovascular Consultants
- Indiana
  - Brownsburg, Indiana, Forente stater, 46112
    - Investigators Research Group, Llc
  - Elwood, Indiana, Forente stater, 46036
    - Investigative Clinical Research of Indiana, LLC
  - Evansville, Indiana, Forente stater, 47714
    - MediSphere Medical Research Center, LLC
  - Evansville, Indiana, Forente stater, 47725
    - Deaconess Clinic Mt. Pleasant
  - Evansville, Indiana, Forente stater, 47713
    - Deaconess Clinic Downtown
  - Evansville, Indiana, Forente stater, 47714
    - Clinical Research Advantage, Inc. (IP Shipment and Research Site)
  - Evansville, Indiana, Forente stater, 47725
    - Clinical Research Advantage, Inc. / Family Medicine Associates
  - Franklin, Indiana, Forente stater, 46131
    - American Health Network of Indiana LLC
  - Greenfield, Indiana, Forente stater, 46140
    - American Health Network of Indiana, LLC
  - Muncie, Indiana, Forente stater, 47304
    - American Health Network of Indiana, LLC
  - Munster, Indiana, Forente stater, 46321
    - Cardiovascular Research of Northwest Indiana, LLC
  - Valparaiso, Indiana, Forente stater, 46383
    - Buynak Clinical Research, P.C.
- Iowa
  - Council Bluffs, Iowa, Forente stater, 51501
    - West Broadway Clinic
  - Council Bluffs, Iowa, Forente stater, 51503
    - Clinical Research Advantage, Inc.
  - Davenport, Iowa, Forente stater, 52803
    - Midwest Cardiovascular Research Foundation
  - Iowa City, Iowa, Forente stater, 52242
    - University of Iowa College of Public Health - Preventive Intervention Center
  - Waterloo, Iowa, Forente stater, 50702
    - Northeast Iowa Medical Education Foundation
  - West Des Moines, Iowa, Forente stater, 50266
    - The Iowa Clinic, PC
- Kansas
  - Hutchinson, Kansas, Forente stater, 67502
    - Hutchinson Clinic, P.A
  - Kansas City, Kansas, Forente stater, 66160
    - University of Kansas Medical Center
  - Newton, Kansas, Forente stater, 67114
    - Heartland Research Associates, LLC
  - Overland Park, Kansas, Forente stater, 66209
    - Midwest Heart & Vascular Specialists, LLC
  - Shawnee Mission, Kansas, Forente stater, 66218
    - Women's & Family Care, LLC D.B.A GTC Research
- Kentucky
  - Elizabethtown, Kentucky, Forente stater, 42701
    - Central Cardiology Associates Research
  - Lexington, Kentucky, Forente stater, 40503
    - The Research Group of Lexington, LLC
  - Louisville, Kentucky, Forente stater, 40213
    - L-MARC Research Center
  - Owensboro, Kentucky, Forente stater, 42303
    - Research Integrity, LLC.
- Louisiana
  - Alexandria, Louisiana, Forente stater, 71301
    - Alexandria Cardiology Clinic
  - Crowley, Louisiana, Forente stater, 70526
    - Avant Research Associates, LLC
  - Lake Charles, Louisiana, Forente stater, 70601
    - Centex Studies
  - Lake Charles, Louisiana, Forente stater, 70601
    - Imperial Health, LLC
  - Marrero, Louisiana, Forente stater, 70072
    - American Clinical Research, LLC
  - Marrero, Louisiana, Forente stater, 70072
    - West Jefferson Heart Clinic of Louisiana New Orleans Physician Services, Inc.
  - Monroe, Louisiana, Forente stater, 71201
    - Clinical Trials of America LA
  - Natchitoches, Louisiana, Forente stater, 71457
    - KAMP Medical Research Inc.
  - Shreveport, Louisiana, Forente stater, 71105
    - Grace Research, LLC
- Maine
  - Auburn, Maine, Forente stater, 04210
    - Maine Research Associates
  - Bangor, Maine, Forente stater, 04401
    - Acadia Clinical Research, LLC
  - Westbrook, Maine, Forente stater, 04092
    - Cranbrook Cardiology Research Associates
- Maryland
  - Annapolis, Maryland, Forente stater, 21401
    - Anne Arundel Medical Center
  - Annapolis, Maryland, Forente stater, 21401
    - Medstar Cardiology Associates
  - Baltimore, Maryland, Forente stater, 21229
    - Maryland Cardiovascular Specialists
  - Baltimore, Maryland, Forente stater, 21236
    - Overlea Personal Physicians
  - Baltimore, Maryland, Forente stater, 21204
    - MedStar Chesapeake CardioVascular Associates
  - Baltimore, Maryland, Forente stater, 21218
    - Medstar Union Memorial Heart Specialists
  - Baltimore, Maryland, Forente stater, 21237
    - Shahid Saeed, MD, PC
  - Glen Burnie, Maryland, Forente stater, 21061
    - Maryland Heart Associates, LLC
  - Lutherville, Maryland, Forente stater, 21093
    - Lutherville Personal Physicians
  - Oxon Hill, Maryland, Forente stater, 20745
    - MD Medical Research
- Massachusetts
  - Framingham, Massachusetts, Forente stater, 01702
    - Metro West Medical Center Research Clinic
  - Framingham, Massachusetts, Forente stater, 01702
    - Metro West Medical Center
  - Framingham, Massachusetts, Forente stater, 01702
    - MetroWest Medical Center - Pharmacy Department
  - Haverhill, Massachusetts, Forente stater, 01830
    - Pentucket Medical Associates, LLC
  - Methuen, Massachusetts, Forente stater, 01844
    - ActivMed Practices and Research, Inc.
  - Natick, Massachusetts, Forente stater, 01760
    - Charles River Medical Associates
- Michigan
  - Alpena, Michigan, Forente stater, 49707
    - Endeavor Medical Research
  - Ann Arbor, Michigan, Forente stater, 48106
    - St. Joseph Mercy Health System
  - Ann Arbor, Michigan, Forente stater, 48106
    - University of Michigan - Domino Farms
  - Chelsea, Michigan, Forente stater, 48118
    - IHA Chelsea Family & Internal Medicine
  - Grandville, Michigan, Forente stater, 49418
    - Healthy Heart Cardiology
  - Kalamazoo, Michigan, Forente stater, 49009
    - Westside Family Medical Center, Pc
  - Lansing, Michigan, Forente stater, 48912
    - Sparrow Clinical Research Institute
  - Lansing, Michigan, Forente stater, 48912
    - Sparrow Thoracic & Cardiovascular Institute
  - Livonia, Michigan, Forente stater, 48154
    - Detroit Clinical Research Center, PC
  - Midland, Michigan, Forente stater, 48670
    - MidMichigan Medical Center Midland
  - Saginaw, Michigan, Forente stater, 48601
    - Michigan Cardio Vascular Institute
  - Sterling Heights, Michigan, Forente stater, 48310
    - Tri-County Research, Inc.
  - Traverse City, Michigan, Forente stater, 49684
    - Medical Research Associates, Inc.
  - Troy, Michigan, Forente stater, 48085
    - Oakland Medical Research Center
  - Troy, Michigan, Forente stater, 48098
    - Arcturus Healthcare, PLC, Troy Internal Medicine Research Division
  - Ypsilanti, Michigan, Forente stater, 48197
    - Michigan Heart & Vascular Institute
- Minnesota
  - Duluth, Minnesota, Forente stater, 55805
    - Duluth Clinic, dba Essentia Health Duluth Clinic Investigational Drug Room
  - Duluth, Minnesota, Forente stater, 55805
    - St. Mary's Medical Center (Primary Practice Site)
  - Edina, Minnesota, Forente stater, 55435
    - Radiant Research, Inc.
  - Golden Valley, Minnesota, Forente stater, 55422
    - Minneapolis Clinic of Neurology
  - Minneapolis, Minnesota, Forente stater, 55407
    - Allina Health System, dba Abbott Northwestern Hospital
  - Minneapolis, Minnesota, Forente stater, 55455
    - Lillehei Clinical Research Unit, University of Minnesota
  - Saint Cloud, Minnesota, Forente stater, 56303
    - CentraCare Heart and Vascular Center
  - Saint Paul, Minnesota, Forente stater, 55102
    - HealthEast Medical Research Institute
  - Saint Paul, Minnesota, Forente stater, 55102
    - HealthEast St. Joseph's Hospital Pharmacy
- Mississippi
  - Jackson, Mississippi, Forente stater, 39209
    - Phillips Medical Services, PLLC
  - Olive Branch, Mississippi, Forente stater, 38654
    - Olive Branch Family Medical Center
  - Tupelo, Mississippi, Forente stater, 38801
    - Cardiology Associates Research, Llc
- Missouri
  - Columbia, Missouri, Forente stater, 65201
    - Missouri Cardiovascular Specialists, LLP
  - Kansas City, Missouri, Forente stater, 64111
    - Saint Luke's Lipid and Diabetes Research Center
  - Kansas City, Missouri, Forente stater, 64128-2226
    - Kansas City VA Medical Center
  - Saint Louis, Missouri, Forente stater, 63141
    - Mercy Research
- Montana
  - Kalispell, Montana, Forente stater, 55901
    - Glacier View Research Institute
  - Kalispell, Montana, Forente stater, 59901
    - Glacier View Research Institute, Cardiology
  - Missoula, Montana, Forente stater, 59808
    - Montana Medical Research Inc.
- Nebraska
  - Elkhorn, Nebraska, Forente stater, 68022
    - Clinical Research Advantage, Inc./Skyline Medical Center, PC
  - Lincoln, Nebraska, Forente stater, 68506
    - Bryan Heart
  - Omaha, Nebraska, Forente stater, 68131
    - Creighton Diabetes Center
  - Omaha, Nebraska, Forente stater, 68198-4120
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forente stater, 68198-4130
    - University of Nebraska Medical Center
- Nevada
  - Las Vegas, Nevada, Forente stater, 89119
    - AB Clinical Trials
  - Las Vegas, Nevada, Forente stater, 89121
    - Clinical Research of South Nevada
  - Las Vegas, Nevada, Forente stater, 89128
    - Clinical Research Advantage, Inc.
- New Jersey
  - Belvidere, New Jersey, Forente stater, 07823
    - John V. Bernard, MD dba Wellness and Research Center
  - Bridgewater, New Jersey, Forente stater, 08807
    - Advanced Heart Care LLC
  - Cherry Hill, New Jersey, Forente stater, 08034
    - Lourdes Cardiology Services
  - Elizabeth, New Jersey, Forente stater, 07201
    - USMA Clinical Research
  - Hammonton, New Jersey, Forente stater, 08037
    - Lourdes Cardiology Services
  - Linden, New Jersey, Forente stater, 07036
    - NJ Heart
  - Lodi, New Jersey, Forente stater, 07644
    - Arysmed LLC
  - Martinsville, New Jersey, Forente stater, 08836
    - Amici Clinical Research, LLC
  - New Brunswick, New Jersey, Forente stater, 08901
    - Rutgers Biomedical and Health Sciences-Robert Wood Johnson Medical School
  - Ridgewood, New Jersey, Forente stater, 07450
    - The Valley Hospital
  - Ridgewood, New Jersey, Forente stater, 07450
    - Cardiac and Endovascular Associates
  - Somerset, New Jersey, Forente stater, 08873
    - Cardio Metabolic Institute
  - Trenton, New Jersey, Forente stater, 08611
    - TLB Research LLC
  - Voorhees, New Jersey, Forente stater, 08043
    - Lourdes Cardiology Services
  - Westwood, New Jersey, Forente stater, 07675
    - Westwood Cardiology Associates
- New Mexico
  - Albuquerque, New Mexico, Forente stater, 87102
    - Albuquerque Clinical Trials, Inc.
- New York
  - Albany, New York, Forente stater, 12206
    - Albany Medical College, Division of Community Endocrinology
  - Brooklyn, New York, Forente stater, 11235
    - NY Scientific
  - Brooklyn, New York, Forente stater, 11214
    - Sorin Medical, P.C.
  - Brooklyn, New York, Forente stater, 11215
    - NY total Medical Care, PC
  - Buffalo, New York, Forente stater, 14215
    - Buffalo Heart Group, LLP
  - Cortlandt Manor, New York, Forente stater, 10567
    - NYU Hudson Valley Cardiology
  - Laurelton, New York, Forente stater, 11413
    - Scott Research,Inc
  - Liverpool, New York, Forente stater, 13088
    - SJH Cardiology Associates
  - Mineola, New York, Forente stater, 11501
    - Long Island Heart Associates
  - New Windsor, New York, Forente stater, 12553
    - Mid Hudson Medical Research, PLLC
  - New York, New York, Forente stater, 10021
    - Weill Cornell Medical College
  - New York, New York, Forente stater, 10016
    - Manhattan Medical Research Practice
  - New York, New York, Forente stater, 10016
    - Peters Medical Research NY, LLC
  - North Massapequa, New York, Forente stater, 11758-1802
    - DiGiovanna Institute for Medical Education and Research
  - Poughkeepsie, New York, Forente stater, 12601
    - Hudson Valley Cardiovascular Practice, PC
  - Rochester, New York, Forente stater, 14609
    - Rochester Clinical Research, Inc.
  - Rosedale, New York, Forente stater, 11422
    - Institute for clinical studies
  - Saratoga Springs, New York, Forente stater, 12866
    - Saratoga Clinical Research, LLC
  - Utica, New York, Forente stater, 13501
    - Central New York Cardiology
  - Westfield, New York, Forente stater, 14787
    - Great Lakes Medical Research
  - Williamsville, New York, Forente stater, 14221
    - Buffalo Medical Group - Research Department
  - Williamsville, New York, Forente stater, 14221
    - Buffalo Medical Group
- North Carolina
  - Burlington, North Carolina, Forente stater, 27215
    - Kernodle Clinic, Department of the Private Diagnostic Clinic, PLLC
  - Charlotte, North Carolina, Forente stater, 28204
    - Novant Health Heart and Vascular Institute
  - Charlotte, North Carolina, Forente stater, 28209
    - PMG Research of Charlotte
  - Charlotte, North Carolina, Forente stater, 28204
    - Novant Health Clinical Research
  - Charlotte, North Carolina, Forente stater, 28277
    - Sensenbrenner Primary Care
  - Clayton, North Carolina, Forente stater, 27520
    - NC Heart and Vascular
  - Greensboro, North Carolina, Forente stater, 27401
    - LeBauer Cardiovascular Research Foundation
  - Hickory, North Carolina, Forente stater, 28601
    - Clinical Trials of America, Inc.
  - High Point, North Carolina, Forente stater, 27262
    - Carolina Cardiology Cornerstone
  - Lenoir, North Carolina, Forente stater, 28645
    - Clinical Trials of America- NC, LLC
  - Mooresville, North Carolina, Forente stater, 28117
    - Research Institute of the Carolinas of PiedmontHealthcare, PA
  - Morganton, North Carolina, Forente stater, 28655
    - Burke Primary Care
  - New Bern, North Carolina, Forente stater, 28562
    - Eastern Nephrology Associates
  - Rocky Mount, North Carolina, Forente stater, 27804
    - Boice Willis Clinic
  - Rocky Mount, North Carolina, Forente stater, 27804
    - PMG Research of Rock Mount, LLC - Patient Intake
  - Statesville, North Carolina, Forente stater, 28625
    - Piedmont Healthcare/Research
  - Wilmington, North Carolina, Forente stater, 28401
    - PMG Research of Wilmington, LLC
  - Winston-Salem, North Carolina, Forente stater, 27157
    - Wake Forest University School of Medicine
- North Dakota
  - Fargo, North Dakota, Forente stater, 58103
    - Lillestol Research LLC
- Ohio
  - Akron, Ohio, Forente stater, 44311
    - Radiant Research, Inc.
  - Cincinnati, Ohio, Forente stater, 45246
    - Sterling Research Group, Ltd.
  - Cincinnati, Ohio, Forente stater, 45227
    - Metabolic and Atherosclerosis Research Center
  - Cincinnati, Ohio, Forente stater, 45219
    - The Lindner Center for Research and Education at The Christ Hospital
  - Cleveland, Ohio, Forente stater, 44122
    - Rapid Medical Research, Inc.
  - Cleveland, Ohio, Forente stater, 44195
    - Cleveland Clinic - Taussig Cancer Institute
  - Columbus, Ohio, Forente stater, 43235
    - Optimed Research, LTD
  - Columbus, Ohio, Forente stater, 43212
    - Radiant Research, Inc.
  - Dayton, Ohio, Forente stater, 45419
    - PriMED Clinical Research
  - Dayton, Ohio, Forente stater, 45414
    - Premier Health Specialists, Inc (dba Dayton Heart Center)
  - Elyria, Ohio, Forente stater, 44035
    - North Ohio Heart Center
  - Elyria, Ohio, Forente stater, 44035
    - North Ohio Heart Center (Administrative Only)
  - Lorain, Ohio, Forente stater, 44053
    - North Ohio Heart Center
  - Marion, Ohio, Forente stater, 43302
    - SV Research, LLC
  - Perrysburg, Ohio, Forente stater, 43551
    - Daniel G. Williams, Md
  - Sandusky, Ohio, Forente stater, 44870
    - North Ohio Heart Center
  - Sandusky, Ohio, Forente stater, 44870
    - North Ohio Heart Center, Inc.
  - Toledo, Ohio, Forente stater, 43615
    - ProMedica Northwest Ohio Cardiology Consultants
  - Youngstown, Ohio, Forente stater, 44501
    - Mercy Health Youngstown, LLC d/b/a St. Elizabeth Youngstown Hospital
- Oklahoma
  - Norman, Oklahoma, Forente stater, 73072
    - Lion Research
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Oklahoma Heart Hospital
  - Oklahoma City, Oklahoma, Forente stater, 73135
    - South Oklahoma Heart Research, LLC
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Oklahoma Heart Hospital Research Foundation
  - Oklahoma City, Oklahoma, Forente stater, 73103
    - COR Clinical Research LLC
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Oklahoma Heart Hospital Physicians
- Oregon
  - Ashland, Oregon, Forente stater, 97520
    - Integrated Medical Research PC
  - Hillsboro, Oregon, Forente stater, 97123
    - Hillsboro Cardiology, P.C.
  - Portland, Oregon, Forente stater, 97225
    - Portland Preventive Cardiology LLC
- Pennsylvania
  - Abington, Pennsylvania, Forente stater, 19001
    - Abington Memorial Hospital (administrative only)
  - Altoona, Pennsylvania, Forente stater, 16602
    - Clinical Research Associates of Central PA
  - Downingtown, Pennsylvania, Forente stater, 19335-2620
    - Brandywine Clinical Research
  - Doylestown, Pennsylvania, Forente stater, 18901
    - Doylestown Cardiology Associates - VIAA
  - Doylestown, Pennsylvania, Forente stater, 18901
    - Doylestown Health Cardiology, a division of Doylestown Health Physicians
  - Feasterville-Trevose, Pennsylvania, Forente stater, 19053
    - Amh/Feasterville Family Health Care Center
  - Jefferson Hills, Pennsylvania, Forente stater, 15025
    - Greater Pittsburgh Vascular
  - Lansdale, Pennsylvania, Forente stater, 19446
    - Detweiler Family Medicine & Associates, PC
  - Lansdale, Pennsylvania, Forente stater, 19446
    - Green and Seidner Family Practice Associates
  - Levittown, Pennsylvania, Forente stater, 19056
    - Family Medical Associates
  - Newtown, Pennsylvania, Forente stater, 18940
    - Mercer Bucks Cardiology
  - Philadelphia, Pennsylvania, Forente stater, 19146
    - Philadelphia Health Associates-Adult Medicine
  - Pittsburgh, Pennsylvania, Forente stater, 15236
    - Preferred Primary Care Physicians
  - Pittsburgh, Pennsylvania, Forente stater, 15212
    - Allegheny Endocrinology Associates
  - Sayre, Pennsylvania, Forente stater, 18840
    - Guthrie Medical Group, PC
  - Scotland, Pennsylvania, Forente stater, 17254
    - SFM Clinical Trials, Inc.
  - Scottdale, Pennsylvania, Forente stater, 15683
    - Fay-West Family Practice
  - Sellersville, Pennsylvania, Forente stater, 18960
    - Grand View - Lehigh Valley Health Services, Buxmont Cardiology Division
  - Smithfield, Pennsylvania, Forente stater, 15478
    - Montgomery Medical, Inc.
  - Uniontown, Pennsylvania, Forente stater, 15401
    - Preferred Primary Care Physicians
  - Wyomissing, Pennsylvania, Forente stater, 19610
    - Berks Cardiologists, Ltd.
- South Carolina
  - Charleston, South Carolina, Forente stater, 29407
    - Coastal Cardiolgy
  - Greenville, South Carolina, Forente stater, 29615
    - Upstate Pharmaceutical Research
  - Greer, South Carolina, Forente stater, 29651
    - Mountain View Clinical Research, Inc.
- South Dakota
  - Rapid City, South Dakota, Forente stater, 57701
    - Black Hills Cardiovascular-Regional Health Research
- Tennessee
  - Clarksville, Tennessee, Forente stater, 37043
    - Mid-Cumberland Infectious Disease Consultants, PLC
  - Collierville, Tennessee, Forente stater, 38017
    - Collierville Medical Specialists
  - Germantown, Tennessee, Forente stater, 38138
    - Stern Cardiovascular Foundation, Inc.
  - Kingsport, Tennessee, Forente stater, 37660
    - Holston Medical Group
  - Knoxville, Tennessee, Forente stater, 37920
    - New Orleans Center for Clinical Research
  - Knoxville, Tennessee, Forente stater, 37920
    - Volunteer Research Group
  - Knoxville, Tennessee, Forente stater, 37909
    - New Phase Research & Development
  - Knoxville, Tennessee, Forente stater, 37912
    - PMG Research,Inc d/b/a PMG Research of Knoxville
  - Knoxville, Tennessee, Forente stater, 37917
    - Cardiovascular Research of Knoxville
  - Memphis, Tennessee, Forente stater, 38119
    - Baptist Memorial Medical Group, Inc.
  - Memphis, Tennessee, Forente stater, 38119
    - The Green Clinic, PC
  - Memphis, Tennessee, Forente stater, 38125
    - Southwind Medical Specialists
  - Tullahoma, Tennessee, Forente stater, 37388
    - Tennessee Center for Clinical Trials
  - Tullahoma, Tennessee, Forente stater, 37388
    - Trinity Clinical Research, LLC
- Texas
  - Amarillo, Texas, Forente stater, 79106
    - PharmaTex Research
  - Arlington, Texas, Forente stater, 76012
    - Arlington Family Research Center, Inc.
  - Austin, Texas, Forente stater, 78731
    - Texas Diabetes & Endocrinology
  - Austin, Texas, Forente stater, 78756
    - Austin Heart, PLLC
  - Beaumont, Texas, Forente stater, 77702
    - Southeast Texas Clinical Research Center
  - Beaumont, Texas, Forente stater, 77702
    - Southeast Texas Cardiology Associates II, L.L.P.
  - Channelview, Texas, Forente stater, 77530
    - Aztec Medical Research, LLC
  - Corsicana, Texas, Forente stater, 75110
    - Corsicana Medical Research, PLLC
  - Dallas, Texas, Forente stater, 75230
    - Dallas Diabetes and Endocrine Center
  - Dallas, Texas, Forente stater, 75231
    - Research Institute Of Dallas
  - Dallas, Texas, Forente stater, 75235
    - Parkland Health and Hospital System
  - Dallas, Texas, Forente stater, 75231
    - Cardiovascular Research Institute of Dallas
  - Dallas, Texas, Forente stater, 75231
    - Radiant Research, Inc.
  - Dallas, Texas, Forente stater, 75204
    - Baylor Research Institute IRB
  - Dallas, Texas, Forente stater, 75208
    - Protenium Clinical Research, LLC
  - Dallas, Texas, Forente stater, 75216
    - VA North Texas Health Care System - Dallas VAMC
  - Dallas, Texas, Forente stater, 75226
    - Baylor Heart and Vascular Institute
  - Dallas, Texas, Forente stater, 75246
    - Baylor University Medical Center / Department of Pharmacy
  - Dallas, Texas, Forente stater, 75390-8565
    - University of Texas Southwestern Medical Center
  - Dallas, Texas, Forente stater, 75390-9034
    - (For IP storage only)The University of Texas Southwestern Medical Center
  - Dallas, Texas, Forente stater, 75390-9034
    - The University of Texas Southwestern Medical Center
  - Dallas, Texas, Forente stater, 75390
    - William P. Clements Jr. University Hospital
  - Edinburg, Texas, Forente stater, 78539
    - Doctors Hospital at Renaissance
  - Fort Worth, Texas, Forente stater, 76164
    - Rockwood Medical Clinic
  - Fort Worth, Texas, Forente stater, 76104
    - Amir Malik Research
  - Fort Worth, Texas, Forente stater, 76104
    - The Medical Group Of Texas
  - Fort Worth, Texas, Forente stater, 76117
    - T & R Clinic, PA
  - Georgetown, Texas, Forente stater, 78626
    - San Gabriel Clinical Research, LLC
  - Houston, Texas, Forente stater, 77030
    - Baylor College of Medicine
  - Houston, Texas, Forente stater, 77058
    - Centex Studies, Inc.
  - Houston, Texas, Forente stater, 77081
    - Texas Center for Drug Development, Inc
  - Houston, Texas, Forente stater, 77030
    - Memorial Hermann Hospital, Texas Medical Center
  - Houston, Texas, Forente stater, 77002
    - Spring Clinical Research
  - Houston, Texas, Forente stater, 77030
    - Investigational Drug Services
  - Houston, Texas, Forente stater, 77024
    - Prime Care Medical Group
  - Houston, Texas, Forente stater, 77002
    - East Texas Cardiology PA
  - Houston, Texas, Forente stater, 77024
    - Med Tech Research, LP
  - Houston, Texas, Forente stater, 77027
    - Associates in Medicine, PA
  - Houston, Texas, Forente stater, 77030
    - Alan S. Hoffman, M.D.
  - Houston, Texas, Forente stater, 77030
    - ICTR/Baylor College of Medicine
  - Houston, Texas, Forente stater, 77030
    - Memorial Hermann Hospital, Texas Medical Center- UT Health Clinical Research Unit
  - Houston, Texas, Forente stater, 77030
    - The University of Texas Health Science Center at Houston- UT Physicians
  - Houston, Texas, Forente stater, 77070
    - Northwest Houston Cardiology, P.A.
  - Houston, Texas, Forente stater, 77094
    - Private Practice Leadership, LLC
  - Hurst, Texas, Forente stater, 76054
    - Protenium Clinical Research LLC
  - Kerrville, Texas, Forente stater, 78028
    - South Texas Cardiovascular Consultants, PLLC
  - Longview, Texas, Forente stater, 75605
    - DCOL Center for Clinical Research
  - Lubbock, Texas, Forente stater, 79410
    - Caprock Cardiac Center Research Institute Inc.
  - Midland, Texas, Forente stater, 79707
    - Midland Clinical Research Center
  - New Braunfels, Texas, Forente stater, 78130
    - Hill Country Medical Associates
  - North Richland Hills, Texas, Forente stater, 76180
    - North Hills Medical Research, Inc.
  - Palestine, Texas, Forente stater, 75801
    - Grace Research, LLC
  - Pasadena, Texas, Forente stater, 77504
    - Med-Olam Clinical Research, LLC.
  - Pflugerville, Texas, Forente stater, 78660
    - Austin Institute for Clinicla Research,Inc.
  - Pharr, Texas, Forente stater, 78577
    - Centex Studies, Inc
  - San Antonio, Texas, Forente stater, 78229
    - University of Texas Health Science Center San Antonio
  - San Antonio, Texas, Forente stater, 78229
    - University of Texas Health Science Center at San Antonio
  - San Antonio, Texas, Forente stater, 78215
    - Sun Research Institute
  - San Antonio, Texas, Forente stater, 78229
    - University of Texas Health Sciences Center at San Antonio
  - San Antonio, Texas, Forente stater, 78221
    - Southwest Clinic
  - San Antonio, Texas, Forente stater, 78201
    - South Texas Cardiovascular Consultants, PLLC
  - San Antonio, Texas, Forente stater, 78229
    - First Outpatient Research Unit
  - San Antonio, Texas, Forente stater, 78231
    - Victorium Clinical Research
  - San Antonio, Texas, Forente stater, 78249
    - Bandera Family Health Care, LLC
  - Schertz, Texas, Forente stater, 78154
    - Northeast Clinical Research of San Antonio, LLC (NECRSA, LLC)
  - Sugar Land, Texas, Forente stater, 77479
    - Sugar Lakes Family Practice
  - Sugar Land, Texas, Forente stater, 77478
    - Acacia Medical Research Institute, LLC/Royal Oaks Medcical Home and Wellness Clinics
  - Sugar Land, Texas, Forente stater, 77478
    - IP + Dry ice deliveries Sugar Lakes Family Practice
  - Tomball, Texas, Forente stater, 77375-4536
    - Northwest Houston Heart Center
  - Tomball, Texas, Forente stater, 77375
    - Northwest Heart Center
  - Tomball, Texas, Forente stater, 77375
    - Admin & Storage only:Northwest Heart Center
  - Tomball, Texas, Forente stater, 77375
    - Northwest Houston Clinical Research, PLLC
  - Victoria, Texas, Forente stater, 77901
    - Victoria Heart & Vascular Center, PA
  - Victoria, Texas, Forente stater, 77901
    - Victoria Heart and Vascular Center, PA
- Utah
  - Bountiful, Utah, Forente stater, 84010
    - Utah Cardiology, PC
  - Layton, Utah, Forente stater, 84041
    - Utah Cardiology, P.C.
  - Ogden, Utah, Forente stater, 84405
    - Paramount Medical Care
  - Orem, Utah, Forente stater, 84058
    - Aspen Clinical Research LLC
  - Provo, Utah, Forente stater, 84604
    - Revere Health
  - Salt Lake City, Utah, Forente stater, 84117
    - Holladay Family Practice
  - Salt Lake City, Utah, Forente stater, 84107
    - Wasatch Clinical Research, LLC
  - Salt Lake City, Utah, Forente stater, 84102
    - Optimum Clinical Research, Inc
  - Salt Lake City, Utah, Forente stater, 84124
    - Heart Center at St. Mark's Hospital
- Virginia
  - Burke, Virginia, Forente stater, 22015
    - Burke Internal Medicine & Research
  - Burke, Virginia, Forente stater, 22015-4202
    - Clinical Research Institute of Northern Virginia
  - Falls Church, Virginia, Forente stater, 22042
    - Virginia Heart
  - Falls Church, Virginia, Forente stater, 22044
    - Seven Corners Medical Research Center
  - Hopewell, Virginia, Forente stater, 23860
    - Heart Care Associates, P.C.
  - Midlothian, Virginia, Forente stater, 23114
    - Virginia Research Center
  - Richmond, Virginia, Forente stater, 23225
    - Chippenham and Johnston Willis Hospitals, Inc. dba CJW Medical Center
  - Richmond, Virginia, Forente stater, 23225
    - Retreat Cardiology LLC, dba Cardiology Associates of Richmond
  - Roanoke, Virginia, Forente stater, 24014
    - Roanoke Heart Institute
  - Suffolk, Virginia, Forente stater, 23435
    - Hampton Roads Center for Clinical Research
- Washington
  - Burien, Washington, Forente stater, 98166
    - The Office of Daniel W. Gottlieb, MD, PS
  - Spokane, Washington, Forente stater, 99202
    - Premier Clinical Research
  - Tacoma, Washington, Forente stater, 98405
    - Universal Research Group, LLC
  - Walla Walla, Washington, Forente stater, 99362
    - Walla Walla Clinic
  - Wenatchee, Washington, Forente stater, 98801
    - Wenatchee Valley Hospital & Clinics
- West Virginia
  - Fairmont, West Virginia, Forente stater, 26554
    - Fairmont General Hospital
- Wisconsin
  - Green Bay, Wisconsin, Forente stater, 54303
    - Prevea Clinic, Inc.
  - Kenosha, Wisconsin, Forente stater, 53142
    - Clinical Investigation Specialists, Inc.
  - Waukesha, Wisconsin, Forente stater, 53188
    - Waukesha Heart Foundation
Frankrike
- - Besancon, Frankrike, 25000
    - CHU Jean Minjoz Cardiologie
  - Bordeaux, Frankrike, 33076
    - Groupe Hospitalier de Pellegrin Hopital Pellegrin
  - Bourg En Bresse Cedex 10000, Frankrike, 01012
    - Centre Hospitalier De Bourg En Bresse - Hopital Fleyriat
  - Corbeil-Essonnes, Frankrike, 91106
    - centre hospitalier Sub-Francilien
  - Essey-Les-Nancy, Frankrike, 54270
    - Scp Cardiovasculaire De L'Est
  - Le Coudray, Frankrike, 28630
    - Centre Hospitalier Louis Pasteur
  - Lille, Frankrike, 59000
    - Hôpital La Louvière
  - Lomme, Frankrike, 59462
    - Centre Hospitalier Saint Philibert
  - Lyon Cedex 03, Frankrike, 69394
    - Hôpital Cardiovasculaire et Pneumologique Louis Pradel
  - Montpellier cedex 5, Frankrike, 34295
    - Hôpital Arnaud de Villeneuve - CHU Montpellier
  - Nantes, Frankrike, 44093
    - CHU de Nantes - Hôpital Nord Laennec
  - Nantes, Frankrike, 44200
    - Nouvelles Cliniques Nantaises
  - Nice Cedex 1, Frankrike, 06002
    - CHU de Nice - Hopital Pasteur
  - Pessac cedex, Frankrike, 33604
    - Hôpital Cardiologique
  - Poitiers Cedex, Frankrike, 86021
    - CHU de Poitiers
  - Rennes Cedex 9, Frankrike, 35033
    - CHU de Renes Hopital de Pontchaillou
  - Toulouse cedex 9, Frankrike, 31059
    - CHU de Toulouse
  - Tourcoing, Frankrike, 59200
    - Hospital Cuy Chatilliez
  - Tours Cedex 9, Frankrike, 37044
    - Hôpital TROUSSEAU
  - Valenciennes, Frankrike, 59300
    - Centre Hospitalier (GH) de Valenciennes
  - Valenciennes, Frankrike, 59300
    - Polyclinique Vauban
India
- Gujarat
  - Ahmedabad, Gujarat, India, 380007
    - Dr. Jivraj Mehta Smarak Health Foundation, Bakeri Medical Research Centre
  - Ahmedabad, Gujarat, India, 380054
    - Apex Heart Institute (A Unit of TCVS Pvt. Ltd)
  - Ahmedabad, Gujarat, India, 380054
    - SAL Hospital
  - Surat, Gujarat, India, 395 002
    - Apple Hospital
  - Surat, Gujarat, India, 395002
    - Unicare Heart Institute & Research Center
  - Surat, Gujarat, India, 395009
    - BAPS - Pramukh Swami Hospital
  - Vadodara, Gujarat, India, 390022
    - Rhythm Heart Institute
- Maharashtra
  - Kolhapur, Maharashtra, India, 416012
    - Aster Aadhar Hospital (Prerana Hospital Ltd.)
  - Nagpur, Maharashtra, India, 440012
    - Shri Krishna Hrudayalaya and Critical Care Centre
  - Pune, Maharashtra, India, 411 001
    - Jehangir Clinical Development Centre Pvt. Ltd.
- Telangana
  - Hyderabad, Telangana, India, 500063
    - Mediciti Hospitals
- Uttar Pradesh
  - Lucknow, Uttar Pradesh, India, 226003
    - M.V. Hospital and Research Centre
Irland
- - Dublin, Irland, 7
    - Mater Misericordiae University Hospital
  - Dublin, Irland, 8
    - St. James'S Hospital
  - Dublin, Irland, 24
    - The Adelaide & Meath Hospital-Dublin Incorporating The National Children's Hospital
  - Galway, Irland
    - Health Research Board
  - Galway, Irland
    - Portiuncula Hospital
- Leinster
  - Dublin, Leinster, Irland, 9
    - Beaumont Hospital
Israel
- - Ashkelon, Israel, 7830604
    - Barzilai Medical Center
  - Bat Yam, Israel, 5955602
    - Gefen Institute for Research and Cardiac Health
  - Beer Sheva, Israel, 84101
    - The Soroka University Medical Center
  - Beer-Sheva, Israel, 84350
    - Ben Yair Community Clinic - Clalit Health Services
  - Hadera, Israel, 38100
    - Heart Institute, Hillel Yaffe Medical Center
  - Haifa, Israel, 31096
    - Rambam Medical Center
  - Haifa, Israel, 34362
    - Cardiovascular Clinical Research Institute
  - Holon, Israel, 58100
    - Edith Wolfson Medical Center
  - Jerusalem, Israel, 91120
    - Hadassah Ein Kerem Medical Center
  - Jerusalem, Israel, 91004
    - Heart Institute, Bikur Cholim Campus, Shaare Zedek Medical Center
  - Kfar Saba, Israel, 44281
    - Meir Medical Center
  - Kfar-Saba, Israel, 44281
    - Meir Medical Center
  - Nahariya, Israel, 22100
    - Galilee Medical Center, Cardiology Department
  - Nazareth, Israel, 16100
    - E.M.M.S Nazareth Hospital
  - Petach Tikva, Israel, 4958202
    - Sha'aria Clinic, Clalit Health Services
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center, Beilinson Hospital
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center-Beilinson Hospital
  - Raanana, Israel, 43452
    - Shuali Community Clinic, Clalit Health Services
  - Ramat Gan, Israel, 52621
    - Department of Neurology & Sagol Neuroscience Center
  - Rehovot, Israel, 76100
    - Kaplan Medical Center
  - Rehovot, Israel, 76100
    - Heart Institute, Kaplan Medical Center
  - Safed, Israel, 13100
    - Internal Medicine A, Ziv Medical Center
  - Tel Aviv, Israel, 6789140
    - Assuta Medical Center
  - Tel HaShomer, Israel, 5265601
    - The Chaim Sheba Medical Center
  - Tel-Aviv, Israel, 64239
    - Tel Aviv Sourasky Medical Center
Italia
- - Ancona, Italia, 60124
    - I.N.R.C.A. di Ancona Ospedale Geriatrico
  - Belluno, Italia, 32100
    - Ospedale Civile Regionale San Martino, Belluno
  - Cagliari, Italia, 09124
    - Azienda Ospedaliera G. Brotzu
  - Naples, Italia, 80131
    - Divisione di Cardiologia con Utic ed Emodinamica
  - Napoli, Italia, 80131
    - Department of Clinical Medicines and Cardiovascular Sciences, Universita "Federico II" di Napoli
  - Napoli, Italia, 80131
    - Divisione di Cardiologia con Utic ed Emodinamica - AOU Federico II di Napoli
  - Reggio Emilia, Italia, 42123
    - A.O. di Reggio Emilia Arcispedale "S. Maria Nuova"/IRCCS
  - Rimini, Italia, 47923
    - AUSL Della Romagna-Ospedale Infermi
  - Rome, Italia, 00161
    - Policlinico Umberto I di Roma - DAI Malattie Cardiovascolari e Respiratorie
  - Rovigo, Italia, 45100
    - Ospedale Santa Maria della Misericordia Azienda ULSS 18 of Rovigo
  - Salerno, Italia, 84100
    - A.O.U. San Giovanni di Dio e Ruggi d'Aragona U.O.C. UTIC
  - Udine, Italia, 33100
    - Azienda Ospedaliera Universitaria Santa Maria della Misericordia
- Bergamo
  - Treviglio (BG), Bergamo, Italia, 24047
    - A.O. Treviglio e Caravaggio
- CZ
  - Catanzaro, CZ, Italia, 88100
    - AOU Policlinico "Mater Domini" UOC di Medicina Interna
- Lecco
  - Merate, Lecco, Italia, 23807
    - Ospedale S. L. Mandic di Merate
- MI
  - Milano, MI, Italia, 20138
    - IRCCS Centro Cardiologico Fondazione Monzino
- PA
  - Palermo, PA, Italia, 90127
    - AOU Policlinico "P. Giaccone" Dipartimento delle Patologie Emergenti, Unita di Medicina Interna
- PG
  - Perugia, PG, Italia, 06132
    - Ospedale S. Maria della Misericordia Dipartimento di Medicina, Medicina Interna,
- Padova
  - Piove Di Sacco, Padova, Italia, 35028
    - Ospedale Civile Di Piove Di Sacco
- Province OF Lecco
  - Lecco, Province OF Lecco, Italia, 23900
    - Azienda Ospedaliera Della Provincia Di Lecco - Ospedale Manzoni
- RM
  - Roma, RM, Italia, 00161
    - Dept."Medicina lnterna e Specialita Mediche" dell' Universita degli
  - Rome, RM, Italia, 00161
    - Policlinico Umberto i di Roma
  - Rome, RM, Italia, 00189
    - Azienda Ospedaliera S'Andrea di Roma - UOC Cardiologia
- VR
  - Verona, VR, Italia, 37126
    - AOUI di Verona - Ospedale Civile Maggiore Borgo Trento
- Venezia
  - San Dona Di Paive, Venezia, Italia, 30027
    - Presidioospedaliero di san dona 'di PIAVE
- Verona
  - San Bonifacio, Verona, Italia, 37047
    - Ospedale G. Fracastoro
Kina
- - Beijing, Kina, 100020
    - Beijing Chao-Yang Hospital
  - Beijing, Kina, 100037
    - FuWai Hospital, CAMS & PUMC
  - Shanghai, Kina, 200080
    - Shanghai General Hospital
  - Tianjin, Kina, 300120
    - Tianjin Union Medical Center
  - Zhejiang, Kina, 317000
    - Taizhou Hospital Of Zhejiang Province
- Guangdong
  - Guangzhou, Guangdong, Kina, 510080
    - Guangdong General Hospital
- Hainan
  - Haikou, Hainan, Kina, 570208
    - Haikou People's Hospital
- Heilongjiang
  - Harbin, Heilongjiang, Kina, 150001
    - The 2nd Affiliated Hospital of Harbin Medical University
  - Harbin, Heilongjiang, Kina, 150001
    - The First Affiliated Hospital of Harbin Medical University
  - Harbin, Heilongjiang, Kina, 150001
    - The First Affiliated Hospital of Habrin Medical University
- Henan
  - Zhengzhou, Henan, Kina, 450052
    - The First Affiliated Hospital of Zhengzhou University
- Hubei
  - Wuhan, Hubei, Kina, 430014
    - The Central Hospital of Wuhan
  - Wuhan, Hubei, Kina, 430033
    - Pu Ai Hospital of Wuhan City
- Hunan
  - Changde, Hunan, Kina, 415003
    - Changde First People's Hospital
  - Changsha, Hunan, Kina, 410004
    - Changsha Central Hospital
  - Changsha, Hunan, Kina, 410005
    - Hunan Provincial People's Hospital
  - Xiangtan, Hunan, Kina, 411100
    - Xiangtan City Central Hospital
  - Zhuzhou, Hunan, Kina, 412007
    - Zhuzhou Central Hospital
- Inner Mongolia
  - Baotou, Inner Mongolia, Kina, 014010
    - Inner Mongolia Baogang Hospital
  - Hohhot, Inner Mongolia, Kina, 010017
    - Inner Mongolia Autonomous Region People's Hospital
- Jiangsu
  - Jiangsu, Jiangsu, Kina, 214023
    - Wuxi People's Hospital
  - Suzhou, Jiangsu, Kina, 215021
    - Suzhou Kowloon Hospital Shanghai Jiaotong University School of Medicine
  - Xuzhou, Jiangsu, Kina, 221002
    - The Affiliated Hospital of Xuzhou Medical College
- Jilin
  - Changchun, Jilin, Kina, 130021
    - The First Hospital of Jilin University
  - Changchun, Jilin, Kina, 130021
    - Jilin Province People's Hospital
  - Changchun, Jilin, Kina, 130033
    - China-Japan Union Hospital of Jilin University
- Ningxia
  - Yinchuan, Ningxia, Kina, 750001
    - General Hospital of Ningxia Medical University
- Shandong
  - Qingdao, Shandong, Kina, 266003
    - The Affiliated Hospital of Qingdao University
- Xinjiang
  - Urumqi, Xinjiang, Kina, 830054
    - The First Affiliated Hospital of Xinjiang Medical University
- Zhejiang
  - Ningbo, Zhejiang, Kina, 315010
    - Ningbo First Hospital
Korea, Republikken
- - Busan, Korea, Republikken, 49201
    - Dong-A University Hospital
  - Busan, Korea, Republikken, 47392
    - Inje University Busan Paik Hospital
  - Daegu, Korea, Republikken, 42472
    - Daegu Catholic University Medical Center
  - Daejeon, Korea, Republikken, 302-718
    - Konyang University Hospital
  - Daejeon, Korea, Republikken, 34943
    - Daejeon St. Mary's Hospital-The Catholic University of Korea
  - Gwangju, Korea, Republikken, 61469
    - Chonnam National University Hospital
  - Incheon, Korea, Republikken, 21565
    - Gachon University Gil Medical Center
  - Seoul, Korea, Republikken, 138-736
    - Asan Medical Center
  - Seoul, Korea, Republikken, 06273
    - Gangnam Severance Hospital, Yonsei University Health System
  - Seoul, Korea, Republikken, 05355
    - Hallym University Kangdong Sacred Heart Hospital
  - Seoul, Korea, Republikken, 07061
    - SMG-SNU Boramae Medical Center
- Chungcheonbuk-do
  - Cheongju-si, Chungcheonbuk-do, Korea, Republikken, 28644
    - Chungbuk National University Hospital
- Gangwon-do
  - Chuncheon-si, Gangwon-do, Korea, Republikken, 24289
    - Kangwon National University Hospital
  - Wonju-Si, Gangwon-do, Korea, Republikken, 26426
    - Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital
- Gyeonggi-do
  - Goyang-Si, Gyeonggi-do, Korea, Republikken, 10380
    - Inje University Ilsan Paik Hospital
  - Goyang-si, Gyeonggi-do, Korea, Republikken, 10326
    - Dongguk University Ilsan Hospital
  - Goyang-si, Gyeonggi-do, Korea, Republikken, 10475
    - MyongJi Hospital
  - Seongnam-si, Gyeonggi-do, Korea, Republikken, 13620
    - Seoul National University Bundang Hospital
  - Suwon-si, Gyeonggi-do, Korea, Republikken, 16499
    - Ajou University Hospital
  - Uijeongbu-si, Gyeonggi-do, Korea, Republikken, 11765
    - Uijeongbu St. Mary's Hospital-The Catholic University of Korea
- Incheon
  - Jung-gu, Incheon, Korea, Republikken, 400-711
    - Inha University Hospital
Mexico
- - Aguascalientes, Mexico, 20127
    - Instituto Biomedico De Investigacion A.C.
  - Aguascalientes, Mexico, 20230
    - Centro de Investigación Cardiométabolica de Aguascalientes S.A. de C.V.
  - Aguascalientes, Mexico, 20230
    - Centro Hospitalario Mac, S.A. De C.V. (Emergencies)
  - Aguascalientes, Mexico, 20230
    - Hospital Cardiologica Aguescalientes
  - Chihuahua, Mexico, 31217
    - Investigacion en Salud y Metabolismo S.C
  - Chihuahua, Mexico, 31203
    - Unidad de Investigación en Salud de Chihuahua S.C.
  - Chihuahua, Mexico, 31215
    - Investigacion En Salud Y Metabolismo S.C.
  - Chihuahua, Mexico, 31217
    - Consultorio Medico de Especialidad Dr. Demetrio Kosturakis Garcia
  - Distrito Federal, Mexico, 14000
    - Instituto Nacional de Ciencia Medicas y Nutricion Salvador Zubiran
  - Durango, Mexico, 34000
    - Lahoja Asociación para la Investigación y Farmacovigilancia S.C.
  - Durango, Mexico, 34080
    - Cardioprevent, S.C.
  - Queretaro, Mexico, 76000
    - Pharmacology and Clinical Research S.A. de C.V.
  - San Luis Potosi, Mexico, 78200
    - Cardioarritmias e Investigación S.C.
  - San Luis Potosi, Mexico, 78218
    - Hospital Lomas de San Luis Intemacional (Emergencies)
  - San Luis Potosi, Mexico, 78240
    - "Hospital Central ""Dr. Ignacio Morones Prieto"""
  - Veracruz, Mexico, 91910
    - Centro Especializado En Diabetes Y Metabolismo
- Chihuahua
  - Cd. Juarez, Chihuahua, Mexico, 32472
    - Consultorio Dr. Leocadio Gerardo Munoz Beltran
- D F
  - Mexico, D F, Mexico, 11650
    - Centro Especializado en Diabetes, Obesidad y Prevención de Enfermedades Cardiovasculares, S.C.
- DF
  - Mexico, DF, Mexico, 06700
    - Centro de Atencion e Investigacion en Factores de Riesgo Cardiovascular Omega S.C
- Distrito Federal
  - Mexico, Distrito Federal, Mexico, 07760
    - Consultorio de Endocrinologia y Nutriologia
  - Mexico, Distrito Federal, Mexico, 07760
    - Operadora de Hospitales Angeles S.A. de C.V.(Emergencies)
  - Mexico, Distrito Federal, Mexico, 14000
    - Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán"
- Guerrero
  - Acapulco de Juarez, Guerrero, Mexico, 39670
    - Centro de Investigacion Clinica del Pacifico, S.A. de C.V.
- Hidalgo
  - Pachuca, Hidalgo, Mexico, 42090
    - Investigacion Biomedica Aplicada de Hidalgo S.A. de C.V.
- Jalisco
  - Guadalajara, Jalisco, Mexico, 44160
    - Centro de Investigación Médica Integral S.C.
  - Guadalajara, Jalisco, Mexico, 44670
    - Unidad de Investigación Clínica y Atención Médica HEPA S.C.
  - Guadalajara, Jalisco, Mexico, 44340
    - Instituto de Terapeutica Experimental y Clinica (INTEC) Centro Universitario de Ciencias de la Salud
  - Guadalajara, Jalisco, Mexico, 44620
    - Hospital Mexico Americano S.C. (Emergencies)
  - Guadalajara, Jalisco, Mexico, 44657
    - Consultorio Privado del Dr. Gabriel Arturo Ramos Lopez
  - Guadalajara, Jalisco, Mexico, 44670
    - CICEJ Centro de Investigacion Clinica Endocrinologica de Jalisco SC
  - Zapopan, Jalisco, Mexico, 45040
    - Jardines Hospital de Especialidades S.A de C.V
- Morelos
  - Cuernavaca, Morelos, Mexico, 62250
    - Instituto de Diabetes Obesidad y Nutricion, S.C.
  - Cuernavaca, Morelos, Mexico, 62270
    - Hospital Inovamed Cuernavaca (Emergencies)
- Nuevo LEON
  - Monterrey, Nuevo LEON, Mexico, 64460
    - Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
  - Monterrey, Nuevo LEON, Mexico, 64718
    - Global Trial Research Center S.A. de C.V.
  - Monterrey, Nuevo LEON, Mexico, 64000
    - Monterrey International Research Center
  - Monterrey, Nuevo LEON, Mexico, 64000
    - Accelerium S. de R.L. de C.V.
  - Monterrey, Nuevo LEON, Mexico, 64000
    - Hospital y Clinica OCA, S.A. de C.V.
  - Monterrey, Nuevo LEON, Mexico, 64060
    - Cardiolink Clin Trials, S.C.
  - Monterrey, Nuevo LEON, Mexico, 64460
    - Hospital Universitario De Monterrey- "Doctor Jose Eleuterio Gonzalez"
  - Monterrey, Nuevo LEON, Mexico, 64710
    - CRI Centro Regiomontano de Investigacion SC
  - San Pedro Garza Garcia, Nuevo LEON, Mexico, 66278
    - Fundacion Santos y de la Garza Evia I.B.P. (Centro Medico Zambrano Hellion)
- Queretaro
  - San Juan del Rio, Queretaro, Mexico, 76800
    - Centro Integral Medico SJR S.C
- Sinaloa
  - Culiacan, Sinaloa, Mexico, 80020
    - Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada S.C.
  - Culiacan, Sinaloa, Mexico, 80020
    - Hospital Angeles Culiacan (Emergencies Only)
- Tamaulipas
  - Tampico, Tamaulipas, Mexico, 89000
    - Centro de Estudios de Investigacion Metabolicos y Cardiovasculares S.C.
- Veracruz
  - Xalapa, Veracruz, Mexico, 91020
    - Centro De Especialidades Medicas Del Estado De Veracruz
Nederland
- - Alkmaar, Nederland, 1815 JD
    - Noordwest Ziekenhuisgroep
  - Almere, Nederland, 1311 RL
    - EB FlevoResearch
  - Amersfoort, Nederland, 3813 TZ
    - Meander Medisch Centrum
  - Amersfoort, Nederland, 3813 TZ
    - Meander Medical Center
  - Amstelveen, Nederland, 1186 AM
    - Amstelland Hospital
  - Amsterdam, Nederland, 1105 AZ
    - Academic Medical Center
  - Amsterdam, Nederland, 1091 AC
    - Onze Lieve Vrouwe Gasthuis
  - Amsterdam, Nederland, 1034 CS
    - BovenIJ ziekenhuis
  - Amsterdam, Nederland, 1061 AE
    - OLVG, locatie West
  - Amsterdam, Nederland, 1081HV
    - VU University Medical Center
  - Apeldoorn, Nederland, 7334 DZ
    - Gelre Hospitals
  - Beverwijk, Nederland, 1942 LE
    - Rode Kruis Ziekenhuis
  - Blaricum, Nederland, 1261 AN
    - Tergooi Ziekenhuis
  - Breda, Nederland, 4818 CK
    - Amphia Ziekenhuis
  - Breda, Nederland, 4811 SW
    - Andro Medical Research B.V.
  - Delft, Nederland, 2625 AD
    - Reinier de Graaf Ziekenhuis
  - Den Haag, Nederland, 2545 CH
    - Hagaziekenhuis
  - Den Haag, Nederland, 2526 HW
    - Hedramed
  - Den Haag, Nederland, 2526HW
    - Hedramed
  - Den Haag, Nederland, 2597 AX
    - HMC (Haaglanden Medisch Centrum) Bronovo
  - Deventer, Nederland, 7416SE
    - Deventer Ziekenhuis
  - Dirksland, Nederland, 3247 BW
    - Van Weel Bethesda Hospital
  - Doetinchem, Nederland, 7009 BL
    - Slingeland Ziekenhuis
  - Dordrecht, Nederland, 3318 AT
    - Albert Schweitzer Hospital
  - Ede, Nederland, 6716 RP
    - Ziekenhuis Gelderse Vallei
  - Eindhoven, Nederland, 5611 NV
    - Andromed Eindhoven
  - Eindhoven, Nederland, 5623 EJ
    - Heartcentre Catharina Hospital
  - Enschede, Nederland, 7512 KZ
    - Medisch Spectrum Twente
  - Gorinchem, Nederland, 4204 AA
    - Beatrix Ziekenhuis
  - Gouda, Nederland, 2803 HH
    - Groene Hart Ziekenhuis
  - Groningen, Nederland, 9713 GZ
    - University Medical Center Groningen
  - Groningen, Nederland, 9728 NT
    - Martini Ziekenhuis
  - Haarlem, Nederland, 2035 RC
    - Spaarne Gasthuis
  - Harderwijk, Nederland, 3844 DG
    - St. Jansdal Ziekenhuis
  - Heerlen, Nederland, 6419 PC
    - Zuyderland Medisch Centrum
  - Heerlen, Nederland, 6419PC
    - Zuyderland
  - Hoogeveen, Nederland, 7909 AA
    - Treant Zorggroep, location Bethesda
  - Hoorn, Nederland, 1624 NP
    - Vascular Research Centre
  - Kloosterhaar, Nederland, 7694 AC
    - Quality Care Research
  - Leeuwarden, Nederland, 8934 AD
    - Medisch Centrum Leeuwarden
  - Leiden, Nederland, 2333 ZA
    - Leiden University Medical Center
  - Leiden, Nederland, 2334 CK
    - Alrijne Ziekenhuis
  - Leiderdorp, Nederland, 2353 GA
    - Alrijne Ziekenhuis
  - Maarssen, Nederland, 3607 KN
    - GCM Maarssenbroek
  - Maastricht, Nederland, 6229 HX
    - Maastricht University Medical Center
  - Meppel, Nederland, 7943 KA
    - Isala Diaconessenhuis
  - Nieuwegein, Nederland, 3435 CM
    - St Antonius hospital
  - Nijmegen, Nederland, 6532 SZ
    - Canisius Wilhelmina Ziekenhuis
  - Nijmegen, Nederland, 6525 GA
    - Radboud University Nijmegen Medical Centre
  - Purmerend, Nederland, 1441 RN
    - Waterland Hospital
  - Rotterdam, Nederland, 3083 AN
    - Ikazia Ziekenhuis
  - Rotterdam, Nederland, 3021 HC
    - Andro Medical Research B.V
  - Rotterdam, Nederland, 3039 BD
    - Rotterdam Research Institute
  - Rotterdam, Nederland, 3045 PM
    - St. Fransiscus Gasthuis
  - Sneek, Nederland, 8601 ZR
    - D&A Research and Genetics
  - Tiel, Nederland, 4002 WP
    - Ziekenhuis Rivierenland
  - Tilburg, Nederland, 5022 GC
    - St. Elisabeth Ziekenhuis
  - Tilburg, Nederland, 5022 GC
    - Elisabeth-TweeSteden Ziekenhuis (previously named St. Elisabeth Ziekenhuis)
  - Tilburg, Nederland, 5042 AD
    - Elisabeth TweeSteden Ziekenhuis (ETZ)
  - Uden, Nederland, 5406 PT
    - Bernhoven Ziekenhuis
  - Utrecht, Nederland, 3584 CX
    - University Medical Center Utrecht
  - Utrecht, Nederland, 3511 NH
    - EB Utrecht
  - Utrecht, Nederland, 3584 CX
    - Universitair Medisch Centrum (UMC) Utrecht - Locatie AZU
  - Veldhoven, Nederland, 5504 DB
    - Maxima Medisch Centrum
  - Venlo, Nederland, 5912 BL
    - VieCuri Medisch Centrum
  - Waalwijk, Nederland, 5141 BM
    - Twee Steden Ziekenhuis
  - Zwijndrecht, Nederland, 3331 LZ
    - Albert Schweitzer Hospital
- Friesland
  - Heerenveen, Friesland, Nederland, 8441 PW
    - Tjongerschans Ziekenhuis
- Limburg
  - Sittard-Geleen, Limburg, Nederland, 6162 BG
    - Zuyderland MC
- Overijssel
  - Zwolle, Overijssel, Nederland, 8025 AB
    - Isala
- Zuid-holland
  - Rotterdam, Zuid-holland, Nederland, 3045 PM
    - St. Franciscus Gasthuis
  - Zoetermeer, Zuid-holland, Nederland, 2725 NA
    - Het Lange Land Ziekenhuis
New Zealand
- - Auckland, New Zealand, 1023
    - Auckland City Hospital
  - Christchurch, New Zealand, 8011
    - Lipid and Diabetes Research Group
  - Christchurch, New Zealand, 8011
    - Southern Clinical Trials Shirley Ltd
  - Christchurch, New Zealand, 8041
    - Southern Clinical Trials Riccarton
  - Dunedin, New Zealand, 9012
    - RMC Medical Research Ltd.
  - New Plymouth, New Zealand, 4310
    - Taranaki Base Hospital
  - Rotorua, New Zealand, 3010
    - Rotorua Hospital
  - Tauranga, New Zealand, 3112 New Zealand
    - Clinical Horizons NZ Ltd.
  - Tauranga, New Zealand, 3112
    - Clinical Trials Unit,Bay of Plenty(BOP) Clinicla School
  - Tauranga, New Zealand, 3118
    - Papamoa Pines Medical Centre
  - Tauranga, New Zealand, 3144
    - Clinical Horizons NZ Ltd
  - Wellington, New Zealand, 6021
    - Wellington Hospital
- Auckland
  - Grafton, Auckland, New Zealand, 1010
    - Optimal Clinical Trials
  - Henderson, Auckland, New Zealand, 0612
    - Henderson Medical Centre
  - Otahuhu, Auckland, New Zealand, 1640
    - Middlemore Hospital
  - Takapuna, Auckland, New Zealand, 0622
    - North Shore Hospital
- Hastings
  - Frimley, Hastings, New Zealand, 4120
    - Hawke's Bay Hospital
Polen
- - Gdynia, Polen, 81-472
    - Marek Piepiorka Gabinet Kardiologiczno - lnternistyczny
  - Krakow, Polen, 30-053
    - Nzoz Gall-Med
  - Krakow, Polen, 31-567
    - NZOZ Centrum Zdrowia i Profilaktyki Dabie Sp. z.o.o.
  - Lublin, Polen, 20-857
    - "TWOJA PRZYCHODNIA" Sp. Z o.o
  - Opole, Polen, 45-706
    - Medicus w Opolu Sp z o. o.
  - Poznan, Polen, 60-592
    - Centrum Zdrowia Metabolicznego Pawel Bogdanski
  - Ruda Slaska, Polen, 41-709
    - NZOZ Przychodnia Specjalistyczna Andrzej wittek Henryk Rudzki S.C.
  - Staszow, Polen, 28-200
    - Ko-Med Centra Kliniczne Staszow
  - Warszawa, Polen, 01-192
    - Synexus Polska Sp. z o.o. Oddzial w Warszawie
  - Warszawa, Polen, 02-097
    - Centrum Medyczne Warszawskiego Uniwersytetu Medycznego Sp. z o.o
  - Warszawa, Polen, 04-628
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego Klinika Kardiologii
  - Wroclaw, Polen, 50-088
    - Synexus Polska Sp. z o.o. Oddzial we Wroclawiu
  - Wroclaw, Polen, 50-306
    - Centrum Opieki Diabetologiczno-Endokrynologicznej i Ginekologiczno-Polozniczej
  - Wroclaw, Polen, 53-301
    - Dobrostan Michal Bogacki
- Dolnoslaskie
  - Jelenia Gora, Dolnoslaskie, Polen, 58-506
    - Jeleniogorskie Centrum Chorob Serca, Przychodnia Kardiologiczna, Poradnia Kardiologiczna
  - Wroclaw, Dolnoslaskie, Polen, 51-314
    - Zdrowie S.C. Agnieszka I Donald Drozdz
  - Zarow, Dolnoslaskie, Polen, 58-130
    - Halina Serafin NZOZ Centrum Medyczne SERAFIN-MED
- Kujawsko-pomorskie
  - Bydgoszcz, Kujawsko-pomorskie, Polen, 85-079
    - NZOZ Vitamed
  - Bydgoszcz, Kujawsko-pomorskie, Polen, 85-231
    - NZOZ Centrum Medyczne KERmed
  - Grudziadz, Kujawsko-pomorskie, Polen, 86-300
    - Specjalistyczna Praktyka Lekarska Piotr Kubalski
  - Wloclawek, Kujawsko-pomorskie, Polen, 87-800
    - Specjalistyczne Gabinety Lekarskie "Medicor Plus" - Jerzy Kopaczewski
- Lodzkie
  - Lodz, Lodzkie, Polen, 90-132
    - Gabinet Lekarski Malgorzata Saryusz-Wolska
  - Lodz, Lodzkie, Polen, 90-368
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego Sp. z o.o. Jednostka 02
  - Lodz, Lodzkie, Polen, 91-490
    - "Prywatny Gabinet Kardiologiczny" Dr N.Med. Maciej Kosmider
  - Lodz, Lodzkie, Polen, 92-003
    - Niepubliczny Zaklad Opieki Zdrowotnej CEREO-MED Sp. z o.o.
  - Piotrkow Trybunalski, Lodzkie, Polen, 97-300
    - Prywatny Gabinet Lekarski Dr n. med. Michal Ogorek
  - Skierniewice, Lodzkie, Polen, 96-100
    - Centrum Medyczne Ogrodowa Sp. z o.o.
- Lubelskie
  - Lublin, Lubelskie, Polen, 20-045
    - Clinical Best Solutions
  - Lublin, Lubelskie, Polen, 20-091
    - Optimamed Specjalistyczne Gabinety Lekarskie
  - Lublin, Lubelskie, Polen, 20-362
    - KO-MED Centra Kliniczne Lublin II
  - Pulawy, Lubelskie, Polen, 24-100
    - KO-MED Centra Kliniczne Pulawy
  - Zamosc, Lubelskie, Polen, 22-400
    - KO-MED Centra Kliniczne Zamosc
- Malopolskie
  - Krakow, Malopolskie, Polen, 30-015
    - LANDA Specjalistyczne Gabinety Lekarskie
  - Krakow, Malopolskie, Polen, 31- 202
    - Krakowski Szpital Specjalistyczny im. Jana Pawla II
  - Krakow, Malopolskie, Polen, 31-121
    - Szpital Specjalistyczny im. J. Dietla w Krakowie, Oddzial Kardiologii
  - Krakow, Malopolskie, Polen, 31-216
    - Centrum Medyczne Zdrowa J. Trebacz, W. Zajdel Spolka Jawna
  - Krakow, Malopolskie, Polen, 31-315
    - Centrum Medyczne A-Z Clinic
  - Krakow, Malopolskie, Polen, 31-501
    - Krakowskie Centrum Medyczne Sp. z o.o.
  - Krakow, Malopolskie, Polen, 31-501
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie,
  - Krakow, Malopolskie, Polen, 31-531
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki W Krakowie, Ambulatoria
  - Krakow, Malopolskie, Polen, 31-567
    - NZOZ Centrum Zdrowia i Profilaktyki Dabie Sp. z.o.o.
  - Krakow, Malopolskie, Polen, 31-637
    - Niepubliczny Zaklad Opieki Zdrowotnej Centrum Medyczne ProMiMed sp z o.o., sp.k.
  - Myslenice, Malopolskie, Polen, 32-400
    - NeuroCor Banaszkiewicz, Kulaga, Ostrowska, Tomaszewski lekarze spolka partnerska
  - Nowy Targ, Malopolskie, Polen, 34-400
    - INTERCARD Sp. z. o. o. Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii w Nowym Targu
  - Oswiecim, Malopolskie, Polen, 32-600
    - Medicome Sp. z o.o.
  - Tarnow, Malopolskie, Polen, 33-100
    - Centrum Szybkiej Diagnostyki Kardiologicznej Kardiomed M. Zabowka E. Zabowka
  - Tarnow, Malopolskie, Polen, 33-100
    - Specjalistyczny Gabinet Lekarski Internistyczno-Kardiologiczny Boguslaw Derlaga
- Mazowieckie
  - Katowice, Mazowieckie, Polen, 40-040
    - Synexus Polska Sp. Z O.O. Oddzial W Katowicach
  - Plock, Mazowieckie, Polen, 09-402
    - Niepubliczny Zaklad Opieki Zdrowotnej Specjalistyczna Przychodnia Lekarska "MEDIKARD"
  - Warszawa, Mazowieckie, Polen, 04-730
    - Specjalistyczny Osrodek Medycyny Wieku Dojrzalego sp. z o.o.
  - Warszawa, Mazowieckie, Polen, 01-875
    - Centrum Medyczne Piaski Filia Nr 9
  - Warszawa, Mazowieckie, Polen, 02-637
    - Instytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynala Wyszynskiego
  - Warszawa, Mazowieckie, Polen, 04-141
    - Wojskowy Instytut Medyczny,Centralny Szpital Kliniczny Ministerstwa Obronty Narodowej
  - Warszawa, Mazowieckie, Polen, 04-628
    - Instytut Kardiologii im
- Podkarpackie
  - Brzozow, Podkarpackie, Polen, 36-200
    - Szpital Specjalistyczny w Brzozowie, Podkarpacki Osrodek Onkologiczny im. Ks. B. Markiewicza Oddzial
  - Krosno, Podkarpackie, Polen, 38400
    - INTERCARD Sp. z o.o. Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii w Krosnie
  - Rzeszow, Podkarpackie, Polen, 35205
    - EMED Centrum Uslug Medycznych Ewa Smialek
- Podlaskie
  - Bialystok, Podlaskie, Polen, 15-351
    - "OSTEO-MEDIC" s.c. Artur Racewicz, Jerzy Supronik
  - Bialystok, Podlaskie, Polen, 15-875
    - Podlaski Osrodek Kardiologii Janusz Korecki
- Pomorskie
  - Gdansk, Pomorskie, Polen, 80-382
    - Synexus Polska Sp. z o.o. Oddzial w Gdansku
  - Gdansk, Pomorskie, Polen, 80-542
    - Niepubliczny Zaklad Opieki Zdrowotnej Gdanskie Centrum Zdrowia, Poradnia Kardiologiczna
  - Gdansk, Pomorskie, Polen, 80-546
    - Centrum Badan Klinicznych Pi-House, Poradnia Diabetologiczna
  - Gdynia, Pomorskie, Polen, 81-338
    - Medica Pro Familia Sp. z o.o. Spolka Komandytowo Akcyjna, Oddzial w Gdyni
  - Gdynia, Pomorskie, Polen, 81-384
    - Synexus Polska Sp. z o.o. Oddzial w Gdyni
  - Gdynia, Pomorskie, Polen, 81-423
    - NZOZ "PRO CORDIS" Sopockie Centrum Badan Kardiologicznych
  - Gdynia, Pomorskie, Polen, 81-472
    - Gabinet Kardiologiczno - lnternistyczny
  - Sopot, Pomorskie, Polen, 81-756
    - Centrum Medyczne "SOPMED" Sp. z o.o.
  - Starogard Gdanski, Pomorskie, Polen, 83-200
    - Indywidualna Specjalistyczna Praktyka Lekarska Malgorzata Biedrzycka
- Slaskie
  - Bytom, Slaskie, Polen, 41-902
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej Wojewodzki Szpital Specjalistyczny Nr 4 w Bytomiu
  - Katowice, Slaskie, Polen, 40-083
    - Bogna Gabrylewicz Andrzej Ochala Unimed s.c.
  - Katowice, Slaskie, Polen, 40-648
    - Pro Familia Altera Poradnia Wielospecjalistyczna
  - Katowice, Slaskie, Polen, 40-752
    - NZOZ Terapia Optima
  - Ruda Slaska, Slaskie, Polen, 41-709
    - Przychodnia Specjalistyczna Samodzielny Publiczny ZOZ w Rudzie Slaskiej,
  - Wola, Slaskie, Polen, 43-225
    - NZOZ "Medyk"Sp. z o. o.
- Swietokrzyskie
  - Kielce, Swietokrzyskie, Polen, 25-315
    - Prywatny Gabinet Lekarski Marianna Janion
- WOJ Mazowieckie
  - Warszawa, WOJ Mazowieckie, Polen, 01-518
    - Centrum Medyczne AMED
- Warminsko-mazurskie
  - Elblag, Warminsko-mazurskie, Polen, 82-300
    - Wojewodzki Szpital Zespolony w Elblagu, Oddzial Kardiologiczny z Pododdzialem Kardiologii Inwazyjnej
  - Ostroda, Warminsko-mazurskie, Polen, 14-100
    - Specjalistyczny Osrodek Leczniczo-Badawczy Zbigniew Zegota
- Wielkopolskie
  - Poznan, Wielkopolskie, Polen, 60-702
    - Synexus Polska Sp. z o.o Oddzial w Poznaniu
  - Poznan, Wielkopolskie, Polen, 61-006
    - Nzoz "Twoja Przychodnia"
- Wojewodztwo Lodzkie
  - Lodz, Wojewodztwo Lodzkie, Polen, 92-213
    - SPZOZ Centralny Szpital Kliniczny Uniwersytetu Medycznego w Lodzi 251 Pomorska
Puerto Rico
- - Anasco, Puerto Rico, 00610
    - The Office of Roberto J. Ayala-Rios, MD - Research Center and Private Practice (DMRA LLC)
  - Ponce, Puerto Rico, 00717
    - Cardiometabolic Research Center, Inc.
  - Ponce, Puerto Rico, 00717
    - Endocrine Lipid Diabetes Research Institute
  - San Juan, Puerto Rico, 00917
    - Consultorio Medico Figueroa
  - San Juan, Puerto Rico, 00917
    - Pradnet Inc.
  - San Juan, Puerto Rico, 00920
    - Altamira Family Medicine And Research Institute
  - San Juan, Puerto Rico, 00926-2832
    - Miguel Sosa-Padilla, MD-Private Practice
  - San Juan, Puerto Rico, 00935
    - Centro de Diabetes para Puerto Rico
Romania
- - Baia Mare, Romania, 430032
    - Euromedica Hospital
  - Braila, Romania, 810249
    - Spitalul Clinic Judetean De Urgenta Braila(Braila County Clincal Emergency Hospital)
  - Brasov, Romania, 500209
    - S.C. Polimed Dacia S.R.L.
  - Brasov, Romania, 500283
    - Centrul Medical de Diagnostic si Tratament Ambulator Neomed
  - Bucharest, Romania, 010192
    - Data Plus Medical Clinic
  - Bucharest, Romania, 020045
    - "Prof. Dr. N.C. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases,
  - Bucharest, Romania, 061118
    - Med Plus SRL (Med Plus Ltd.)
  - Bucharest, Romania, 20614
    - S.C. Centrul Medical "Sanatatea Ta" S.R.L.
  - Bucuresti, Romania, 010825
    - Spitalul Universitar De Urgenta Militar Central, Dr. Carol Davila
  - Bucuresti, Romania, 020125
    - Spitalul Clinic Colentina, Departament Cardiologie
  - Bucuresti, Romania, 021611
    - SC Clinica Medicala Synexus SRL, Medicina Interna
  - Bucuresti, Romania, 021967
    - SC Centrul Medical Policlinico Di Monza SRL, Cardiologie
  - Bucuresti, Romania, 030463
    - SC Policlinica CCBR SRL
  - Cluj, Romania, 400006
    - Spitalul Clinic Judetean de Urgenta Cluj-Napoca, Diabet Zaharat, Nutritie si Boli Metabolice
  - Galati, Romania, 800098
    - Dr. Mistodie Cristina Victoria MD, Office of
  - Galati, Romania, 800291
    - S.C. Diamed Obesity S.R.L.
  - Satu Mare, Romania, 440055
    - County Emergency Hospital Satu Mare Diabetes, Nutrition And Metabolic Diseases Department
  - Sibiu, Romania, 550245
    - County Clinical Emergency Hospital Sibiu
  - Targu Mures, Romania, 540124
    - Cardio Med SRL
  - Timisoara, Romania, 300456
    - Centrul Medical Dr. Negrisanu SRL, Diabet Zaharat, Nutritie si Boli Metabolice
- Arges
  - Pitesti, Arges, Romania, 110084
    - Pitesti-Arges County Emergency Hospital
- Bihor
  - Oradea, Bihor, Romania, 410032
    - Medical Practice SRL
  - Oradea, Bihor, Romania, 410169
    - County Clinical Emergency Hospital Oradea
- Hunedoara
  - Deva, Hunedoara, Romania, 330084
    - County Emergency Hospital Deva
- JUD. Timis
  - Timisoara, JUD. Timis, Romania, 300125
    - Centrul Medical Sf. Stefan
- Maramures
  - Baia Mare, Maramures, Romania, 430130
    - Dr. Pop Calin Florin - Cabinet Cardiologie
- Mures
  - Targu Mures, Mures, Romania, 540143
    - Podoleanu G. Cristian-Gheorghe-Calin - Cardiology Medical Practice
- Prahova
  - Ploiesti, Prahova, Romania, 100163
    - Diabmed Dr. Popescu Alexandrina SRL, Diabet, Nutritie, Boli Metabolice
  - Ploiesti, Prahova, Romania, 100342
    - Dr. Busegeanu Mihaela Private Practice
- Timis
  - Timisoara, Timis, Romania, 300310
    - Institute of Cardiovascular Diseases Timisoara
Slovakia
- - Banska Bystrica, Slovakia, 975 17
    - Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica
  - Banska Bystrica, Slovakia, 974 01
    - Stredoslovensky ustav srdcovych a cievnych chorob a.s.
  - Bardejov, Slovakia, 08501
    - Alian s.r.o., kardiologicka ambulancia
  - Bratislava, Slovakia, 811 08
    - METABOL KLINIK s. r.o., Ambulancia pre diabetologiu, poruchy latkovej premeny a vyzivy
  - Bratislava, Slovakia, 81369
    - Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto, l.intema klinika
  - Bratislava, Slovakia, 81369
    - Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto, l.interna klinika
  - Bratislava, Slovakia, 81369
    - Univerzitna nemocnica Bratislava, Nemocnica Stare Mesto
  - Bratislava, Slovakia, 826 06
    - UN Bratislava, Nemocnica Ruzinov, V. interna klinika LFUK a UN Bratislava
  - Bratislava, Slovakia, 83101
    - Kardiovaskularne Centrum S.R.O.
  - Bratislava, Slovakia, 83101
    - Metabolicke centrum MUDr. Katariny Raslovej, s.r.o.
  - Bratislava, Slovakia, 833 48
    - Narodny ustav srdcovych a cievnych chorob, a.s.
  - Bratislava, Slovakia, 83305
    - Univerzitna nemocnica Bratislava
  - Bratislava, Slovakia, 83348
    - Narodny ustav srdcovych a cievnych chorob, a.s.
  - Bratislava, Slovakia, 84108
    - KARDIO-SANUS spol., s.r.o.
  - Bratislava, Slovakia, 851 07
    - UN Bratislava Nemocnica Sv. Cyrila a Metoda, kardiologicka ambulancia 1
  - Bratislava, Slovakia, 85101
    - VERIA, s.r.o. -Kardiologicka ambulancia
  - Dolny Kubin, Slovakia, 02601
    - Endiamed s.r.o. Nestatna diabetologicka a endokrinologicka ambulancia
  - Dolny Kubin, Slovakia, 02601
    - JM-Interna s.r.o., interna ambulancia
  - Kosice, Slovakia, 040 01
    - CARDIO D&R s.r.o. , Kardiologicka ambulancia
  - Kosice, Slovakia, 04011
    - AGTO., spol. s r. o.
  - Kosice, Slovakia, 04022
    - Cardio D&R spol.s.r.o., kardiologicka ambulancia
  - Kralovsky Chlmec, Slovakia, 077 01
    - Medicentrum Heart, Spol. S.R.O
  - Levice, Slovakia, 93405
    - CELL-B s.r.o. interna ambulancia
  - Liptovsky Mikulas, Slovakia, 031 23
    - Liptovska nemocnica s poliklinikou MUDr.Ivana Stodolu Liptovsky Mikulas
  - Lucenec, Slovakia, 984 39
    - KARDIO 1 s.r.o.
  - Martin, Slovakia, 03659
    - Klinika hematologie a transfuziologie, Univerzitna nemocnica Martin
  - Moldava nad Bodvou, Slovakia, 045 01
    - MEDI M&M s.r.o., Ambulancia vnutorneho lekarstva
  - Namestovo, Slovakia, 02901
    - MUDr. Kanderkova s.r.o., Diabetologicka ambulancia
  - Nitra, Slovakia, 94901
    - Kardiocentrum Nitra s.r.o., kardiologicka ambulancia
  - Nove Zamky, Slovakia, 940 34
    - Fakultna nemocnica s poliklinikou Nove Zamky
  - Pezinok, Slovakia, 90201
    - Mediab s.r.o. Diabetologicka ambulancia
  - Piestany, Slovakia, 921 01
    - BENIMED s.r.o.
  - Presov, Slovakia, 08001
    - Medispol s.r.o.
  - Rimavska Sobota, Slovakia, 979 01
    - Medilex s.r.o. Interna ambulancia
  - Rimavska Sobota, Slovakia, 97901
    - Kardioamb S.R.O.
  - Trencin, Slovakia, 911 01
    - DIAMEL, s.r.o., Diabetologicka ambulancia
  - Trnava, Slovakia, 917 01
    - BV Medical, s.r.o. Diabetologicka ambulancia,
  - Trnava, Slovakia, 917 01
    - Kardiologicka ambulancia
  - Zilina, Slovakia, 010 01
    - MEDIVASA, s.r.o.
- Bratislavsky
  - Bratislava, Bratislavsky, Slovakia, 826 06
    - Nemocnica Ruzinov-Univerzitna Nemocnica Bratislava (UNB)
Spania
- - A Coruna, Spania, 15006
    - Complejo Hospitalario Universitario A Coruna
  - A Coruna, Spania, 15001
    - Hospital Abente y Lago
  - Albacete, Spania, 02006
    - Complejo Hospitalario Universitario de Albacete
  - Alicante, Spania, 03010
    - Hospital General Universitario de Alicante; Servicio Cardiologia
  - Almeria, Spania, 04120
    - Hospital Virgen del Mar
  - Barcelona, Spania, 08025
    - Hospital de la Santa Creu i Sant Pau
  - Barcelona, Spania, 08035
    - Hospital Universitari Vall d'Hebron
  - Barcelona, Spania, 08003
    - Parc de Salut mar ¿ Hospital del Mar
  - Barcelona, Spania, 08003
    - Parc de Salut Mar-Hospital del Mar
  - Barcelona, Spania, 08022
    - Centre Teknon
  - Barcelona, Spania, 08025
    - EAP Sardenya
  - Barcelona, Spania, 08540
    - CAP Centelles
  - Barcelona, Spania, 08923
    - Fundacio Hospital de I'Esperit Sant
  - Barcelona/Cataluna, Spania, 08820
    - CAP Disset De Setembre (Sant Cosme I Sant Damia)
  - Barcelona/Cataluña, Spania, 08400
    - Hospital General de Granollers
  - Ciudad Real, Spania, 13005
    - H. General Universitario de Ciudad Real
  - Cordoba, Spania, 14004
    - Hospital Universitario Reina Sofía
  - Ferrol, Spania, 15401
    - Complexo Hospitalario Universitario Arquitecto Marcide-Profesor Novoa Santos De Ferrol
  - Granada, Spania, 18014
    - Hospital Universitario Virgen de las Nieves (HUVN)
  - Granada, Spania, 18012
    - Hospital Universitario San Cecilio de Granada
  - Lleida, Spania, 25198
    - Hospital Universitari Arnau de Vilanova
  - Lugo, Spania, 27003
    - Hospital Universitario Lucus Augusti
  - Madrid, Spania, 28040
    - Fundación Jiménez Díaz
  - Madrid, Spania, 28034
    - Hospital Universitario Ramón y Cajal
  - Madrid, Spania, 28040
    - Hospital Universitario Fundación Jiménez Díaz
  - Madrid, Spania, 28006
    - Hospital Universitario de la Princesa
  - Madrid, Spania, 28007
    - Hospital General Universitario Gregorio Marañón
  - Madrid, Spania, 28223
    - Hospital Universitario Quiron Madrid
  - Madrid, Spania, 28029
    - Hospital Carlos III
  - Madrid, Spania, 28046
    - Hospital Universitario La Paz; Unidad Metabolico-Vascular
  - Malaga, Spania, 29010
    - Hospital Universitario Virgen de la Victoria
  - Malaga, Spania, 29006
    - Hospital Universitario Virgen de la Victoria
  - Malaga, Spania, 29009
    - Hospital Regional Universitario de Málaga
  - Murcia, Spania, 30008
    - Hospital General Universitario Morales Meseguer
  - Sevilla, Spania, 41009
    - Hospital Universitario Virgen Macarena
  - Sevilla, Spania, 41013
    - Hospital Universitario Virgen del Rocío
  - Sevilla, Spania, 41014
    - Hospital Universitario Virgen de Valme
  - Sevilla, Spania, 41003
    - Clínica Nuevas Tecnologías en Diabetes y Endocrinología
  - Tarragona, Spania, 43002
    - CAP Muralles
  - Valencia, Spania, 46014
    - Hospital General Universitario de Valencia
  - Vigo, Spania, 36312
    - Hospital Alvaro Cunqueiro (Hospital Meixoerio)
  - Zaragoza, Spania, 50009
    - Hospital Clinico Universitario Miguel Servet; Medicina Interna
- A Coruna
  - Santiago de Compostela, A Coruna, Spania, 15706
    - Hospital Clinico Universitario de Santiago de Compostela
  - Santiago de Compostela, A Coruna, Spania, 15706
    - Hospital Universitario de Santiago de Compostela
- Alicante
  - Alcoy, Alicante, Spania, 03804
    - Hospital Virgen de los Lirios
  - Elda, Alicante, Spania, 03600
    - Hospital General Comarcal de Elda Virgen de la Salud
- Andalucia
  - Malaga, Andalucia, Spania, 29010
    - Hospital Regional Universitario de Málaga
  - Sevilla, Andalucia, Spania, 41013
    - Hospital Universitario Virgen del Rocío
- Asturias
  - Oviedo, Asturias, Spania, 33006
    - Centro de Salud El Cristo
  - Oviedo, Asturias, Spania, 33009
    - Centro Salud Paulino Prieto
- Barcelona
  - L'Hospitalet de Llobregat, Barcelona, Spania, 08907
    - Hospital Universitari de Bellvitge
  - L'Hospitalet de Llobregat, Barcelona, Spania, 08907
    - Hospital Universitario de Bellvitge
  - Sant Adria De Besos, Barcelona, Spania, 08930
    - CAP La Mina
  - Vic, Barcelona, Spania, 08500
    - EAP Vic
- Barcelona-cataluna
  - L'Hospitalet De Llobregat, Barcelona-cataluna, Spania, 08905
    - CAP Florida
- Barcelona/cataluña
  - Granollers, Barcelona/cataluña, Spania, 08400
    - Hospital General de Granollers
- Cantabria
  - Santander, Cantabria, Spania, 39008
    - Hospital Universitario Marqués de Valdecilla
- Catalonia
  - Lleida, Catalonia, Spania, 25198
    - Institut Catala De La Salut - Hospital Universitari Arnau De Vilanova (Huav)
  - Tarragona, Catalonia, Spania, 43007
    - Hospital Universitari de Tarragona Joan XXIII
- Comunidad Valenciana
  - San Juan De Alicante (Alicante), Comunidad Valenciana, Spania, 03550
    - Hospital Universitario San Juan de Alicante
- Gerona
  - Peralada, Gerona, Spania, 17491
    - Albera Salut
- Girona-catalonia
  - Figueres, Girona-catalonia, Spania, 17600
    - Hospital de Figueres
- Illes Balears
  - Inca, Illes Balears, Spania, 07300
    - Hospital Comarcal d'Inca
- Islas Baleares
  - Palma de Mallorca, Islas Baleares, Spania, 07198
    - Hospital Son Llatzer
  - Palma de Mallorca, Islas Baleares, Spania, 07014
    - Clínica Juaneda
- LA Coruna
  - El Ferrol, LA Coruna, Spania, 15405
    - Hospital Arquitecto Marcide
- Madrid
  - Alcala De Henares, Madrid, Spania, 28805
    - H. U. Principe de Asturias
  - Alcala De Henares, Madrid, Spania, 28805
    - Hospital Principe de Asturias
  - Alcala De Henares, Madrid, Spania, 28805
    - Hospital Universitario Príncipe de Asturias
  - Alcorcon, Madrid, Spania, 28922
    - Hospital Universitario Fundación Alcorcón
  - Majadahonda, Madrid, Spania, 28222
    - Hospital Universitario Puerta de Hierro - Majadahonda
  - Majadahonda, Madrid, Spania, 28222
    - Hospital Universitario Puerta de Hierro
- Navarra
  - Pamplona, Navarra, Spania, 31008
    - Complejo Hospitalario de Navarra
- Oviedo Asturias
  - Colloto, Oviedo Asturias, Spania, 33010
    - Consultorio de Colloto
- PAIS Vasco
  - Barakaldo, PAIS Vasco, Spania, 48903
    - Hospital Universitario de Cruces
- Tarragona
  - Reus, Tarragona, Spania, 43204
    - Hospital Universitario Sant Joan de Reus
- Valencia
  - Requena, Valencia, Spania, 46340
    - Hospital General de Requena
Storbritannia
- - Barnet, Storbritannia, EN5 3DJ
    - Royal Free London NHS Foundation Trust
  - Belfast, Storbritannia, BT12 6BA
    - Royal Victoria Hospital
  - Birmingham, Storbritannia, B6 6BB
    - Laurie Pike Health Centre
  - Birmingham, Storbritannia, B9 5SS
    - Heart of England NHS Foundation Trust, Dept. of Clinical Biochemistry & Immunology
  - Bolton, Storbritannia, BL4 0JR
    - Royal Bolton Hospital - Bolton NHS Foundation Trust
  - Cardiff, Storbritannia, CF14 5GJ
    - Synexus Wales Clinical Research Centre
  - Chesterfield, Storbritannia, S404AA
    - Ashgate Medical Practice
  - East Sussex, Storbritannia, TN37 7RD
    - Conquest Hospital - East Sussex Healthcare NHS Trust
  - East Sussex, Storbritannia, TN39 4SP
    - Little Common Surgery
  - East Sussex, Storbritannia, TN40 1JJ
    - Sea Road Surgery
  - Ely, Storbritannia, CB7 5JD
    - Staploe Medical Centre
  - Glasgow, Storbritannia, G51 4TF
    - The Queen Elizabeth University Hospital- NHS Greater Glasgow and Clyde
  - Glasgow, Storbritannia, G69 7AD
    - McGlone Practice Baillieston Health Centre
  - Hinckley, Storbritannia, LE10 2SE
    - Burbage Surgery
  - London, Storbritannia, NW3 2QG
    - Royal Free Hospital
  - London, Storbritannia, EC1M 6BQ
    - William Harvey Heart Centre (WHHC)
  - London, Storbritannia, W12 OHS
    - Peart-Rose Research Unit, Hammersmith Hospital, Imperial College NHS Trust
  - Middlesbrough, Storbritannia, TS4 3BW
    - The Red Porto cabin, The James Cook University Hospital
  - Newport, Storbritannia, PO30 5TG
    - St Mary's Hospital
  - Peterborough, Storbritannia, PE8 6PL
    - Wansford and Kings Cliffe Practice
  - Rothwell, Northants, Storbritannia, NN14 6JQ
    - Rothwell and Desborough Healthcare Group
  - Swansea, Storbritannia, SA2 8PP
    - Abertawe Bro Morgannwg University Local Health Board
  - Worthing, Storbritannia, BN11 2DH
    - Western Sussex Hospitals NHS Trust
  - York, Storbritannia, YO30 6AE
    - York Medical Group
  - York, Storbritannia, YO32 5UA
    - Strensall Healthcare Centre
- Berkshire
  - Reading, Berkshire, Storbritannia, RG2 0TG
    - Synexus Thames Valley Clinical Research Centre
- Buckinghamshire
  - Aylesbury, Buckinghamshire, Storbritannia, HP22 5LB
    - Westongrove Research Centre
- Cambridgeshire
  - Peterborough, Cambridgeshire, Storbritannia, PE3 9GZ
    - Peterborough City Hospital
- Cornwall
  - Penzance, Cornwall, Storbritannia, TR18 4EL
    - Morrab Surgery
  - St Austell, Cornwall, Storbritannia, PL26 7RL
    - Brannel Surgery
- EAST Yorkshire
  - Hull, EAST Yorkshire, Storbritannia, HU3 2RW
    - The Michael White Centre for Diabetes & Endocrinology, Hull Royal Infirmary
- Essex
  - Romford, Essex, Storbritannia, RM7 0AG
    - Queen's Hospital
- Greater Manchester
  - Manchester, Greater Manchester, Storbritannia, M15 6SX
    - Synexus Manchester Clinical Research Centre-Manchester Science Park
  - Oldham, Greater Manchester, Storbritannia, OL1 2JH
    - Royal Oldham Hospital
- Hampshire
  - Chandlers Ford, Hampshire, Storbritannia, SO53 2ZH
    - St Francis Surgery
- Hertfordshire
  - Stevenage, Hertfordshire, Storbritannia, SG1 4AB
    - Lister Hospital
  - Welwyn Garden City, Hertfordshire, Storbritannia, AL7 4HQ
    - East and North Hertfordshire NHS Trust
  - Welwyn Garden City, Hertfordshire, Storbritannia, AL7 4HQ
    - Howlands Clinic - Queen Elizabeth II Hospital
- Lanarkshire
  - Glasgow, Lanarkshire, Storbritannia, G20 0SP
    - Synexus Scotland Clinical Research Centre
- Lancashire
  - Blackpool, Lancashire, Storbritannia, FY3 7EN
    - Layton Medical Centre
  - Chorley, Lancashire, Storbritannia, PR7 7NA
    - Synexus Lancashire Clinical Research Centre
- M6 8hd
  - Salford, M6 8hd, Storbritannia, M6 8HD
    - Salford Royal NHS Foundation Trust - Dermatology Centre
- Merseyside
  - Liverpool, Merseyside, Storbritannia, L22 0LG
    - Synexus Merseyside Clinical Research Centre
  - Liverpool, Merseyside, Storbritannia, L78XP
    - The Royal Liverpool and Broadgreen -University Hospitals NHS Trust
- North Yorkshire
  - Whitby, North Yorkshire, Storbritannia, YO21 1SD
    - Whitby Group Practice
- Northants
  - Wellingborough, Northants, Storbritannia, NN84RW
    - Albany House Medical Centre
- Northern Ireland
  - Portadown, Northern Ireland, Storbritannia, BT63 5QQ
    - Southern Health & Social Care Trust, Craigavon Area Hospital
- Northumberland
  - Hexham, Northumberland, Storbritannia, NE46 1QJ
    - Synexus North East Clinical Research Centre - Hexham General Hospital
- South Yorkshire
  - Doncaster, South Yorkshire, Storbritannia, DN9 2HY
    - South Axholme Practice
  - Manchester, South Yorkshire, Storbritannia, M13 9WL
    - Central Manchester University Hospitals NHS Foundation Trust
- Surrey
  - Addlestone, Surrey, Storbritannia, KT15 2BH
    - The Crouch Oak Family Practice
- WEST Midlands
  - Birmingham, WEST Midlands, Storbritannia, B15 2SQ
    - Synexus Midlands Clinical Research Centre
  - Birmingham, WEST Midlands, Storbritannia, B18 7QH
    - City Hospital
- WEST Wales
  - Llanelli, WEST Wales, Storbritannia, SA14 8QF
    - Prince Philip Hospital
- Wales
  - Cardiff, Wales, Storbritannia, CF5 4AD
    - Ely Bridge Surgery
- West Mids
  - Birmingham, West Mids, Storbritannia, B9 5SS
    - Heart of England NHS Trust
Sveits
- - Geneve, Sveits, 1211
    - Hopitaux Universitaires de Geneve
  - Lugano, Sveits, CH-6900
    - Cardiocentro Ticino
  - Luzern 16, Sveits, CH-6000
    - Luzerner Kantonsspital Luzern
  - St. Gallen, Sveits, CH-9007
    - Kantonsspital St. Gallen
- Basel Stadt
  - Basel, Basel Stadt, Sveits, 4031
    - Universitätsspital
- Basel Switzerland
  - Reinach, Basel Switzerland, Sveits, 4153
    - Diagene Laboratories
- Ticino
  - Lugano, Ticino, Sveits, 6900
    - Fondazione Diabete Lugano
- VD
  - Lausanne, VD, Sveits, 1011
    - Centre Hospitalier Universitaire Vaudois (CHUV)
- Vaud
  - Lausanne, Vaud, Sveits, 1011
    - Policlinique Medicale Universitaire
- Zurich
  - Winterthur, Zurich, Sveits, 8401
    - Kantonsspital Winterthur
Sverige
- - Eksjö, Sverige, 57535
    - Kasernens Läkarservice AB
  - Goteborg, Sverige, 413 45
    - Clinical Trial Center (CTC)/Centrum foer klinisk proevning
  - Goteborg, Sverige, 41345
    - Sahlgrenska Universitetssjukhuset
  - Gothenburg, Sverige, 41345
    - Centrum for klinisk provning-Sahlgrenska Universitetssjukhus
  - Helsingborg, Sverige, 25220
    - Pharmasite AB
  - Karlstad, Sverige, 65185
    - Centralsjukhuset Karlstad
  - Kristianstad, Sverige, 291 85
    - Centralsjukhuset Kristianstad
  - Lund, Sverige, 221 21
    - Capio Citykliniken Hjartmottagning
  - Lund, Sverige, 222 22
    - Probar E Lund AB
  - Malmo, Sverige, 205 02
    - Karlkliniken, Skanes Universitetssjukhus i Malmo
  - Malmo, Sverige, 211 52
    - PharmaSite
  - Molndal, Sverige, 431 80
    - Forskningsenheten, Medicinmottagningen Sahlgrenska Universitetssjukhuset/Molndal, Hus J
  - Ostersund, Sverige, 83183
    - Östersunds Sjukhus
  - Rattvik, Sverige, 79530
    - Dalecarlia Clinical Research Center
  - Skelleftea, Sverige, 93186
    - Skellefteå lasarett
  - Stockholm, Sverige, 118 83
    - Sodersjukhuset AB
  - Stockholm, Sverige, 111 57
    - Citydiabetes
  - Stockholm, Sverige, 113 24
    - Karolinska Trial Alliance, KTA Prim
  - Stockholm, Sverige, 17176
    - Karolinska Universitetssjukhuset
  - Stockholm, Sverige, 188 82
    - Hjartkliniken
  - Uppsala, Sverige, 75185
    - Akademiska sjukhuset
  - Vasteras, Sverige, 721 89
    - Västmanlands sjukhus Västerås
- Huddinge
  - Stockholm, Huddinge, Sverige, 141 86
    - Karolinska Universitetssjukhuset Huddinge
Sør-Afrika
- - Arcadia, Pretoria, Sør-Afrika, 0001
    - Global Clinical Trials (Pty) Ltd.
  - Centurion, Sør-Afrika, 0157
    - Unitas Hospital
  - Gauteng, Sør-Afrika, 1619
    - Clinresco Centres (Pty) Ltd-Central Professional Suits
  - Johannesburg, Sør-Afrika, 2198
    - Centre for Diabetes and Endocrinology
  - Paarl, Sør-Afrika, 7646
    - Paarl Research Centre
  - Parow, Sør-Afrika, 7500
    - TREAD Research CC
  - Worcester, Sør-Afrika, 6850
    - Clinical Projects Research SA (PTY) LTD
- Durban
  - Merebank, Durban, Sør-Afrika, 4052
    - Nash Ranjith Research Centre
- FREE State
  - Bloemfontein, FREE State, Sør-Afrika, 9301
    - Josha Research
  - Bloemfontein, FREE State, Sør-Afrika, 9301
    - Iatros International
  - Welkom, FREE State, Sør-Afrika, 9460
    - Welkom Clinical Trial Centre
- Gauteng
  - Halfway House, Gauteng, Sør-Afrika, 1685
    - Midrand Medical Centre
  - Johannesburg, Gauteng, Sør-Afrika, 1459
    - Sunward Park Hospital
  - Johannesburg, Gauteng, Sør-Afrika, 2157
    - Sunninghill Hospital
  - Lyttelton, Gauteng, Sør-Afrika, 0157
    - I Engelbrecht Research (Pty) Ltd
  - Parktown, Gauteng, Sør-Afrika, 2193
    - Charlotte Maxeke Johannesburg Academic Hospital
  - Pretoria, Gauteng, Sør-Afrika, 0184
    - Synexus Watermeyer Clinical Research Centre
  - Pretoria, Gauteng, Sør-Afrika, 0158
    - Medipark Centre for Clinical Research
  - Pretoria West, Gauteng, Sør-Afrika, 0183
    - Jongaie Research
  - Roodepoort, Gauteng, Sør-Afrika, 1724
    - Roodepoort Medicross Clinical Research Centre
  - Soweto, Gauteng, Sør-Afrika, 2013
    - Wits Clinical Research
  - Sunnyside, Gauteng, Sør-Afrika, 0083
    - Medi-Clinic Heart Hospital
- Johannesburg
  - Sunninghill, Johannesburg, Sør-Afrika, 2191
    - Sunninghill Hospital
- Kwazulu-natal
  - Durban, Kwazulu-natal, Sør-Afrika, 4001
    - Glastonbury Medical Research Centre
  - Durban, Kwazulu-natal, Sør-Afrika, 4001
    - Suite 502
  - Durban, Kwazulu-natal, Sør-Afrika, 4091
    - Dr Ganesh c/o Dr NB Maharaj
- Limpopo
  - Thabazimbi, Limpopo, Sør-Afrika, 0380
    - Limpopo Clinical Research Initiative
- Mpumalanga
  - Moloto, Mpumalanga, Sør-Afrika, 1022
    - Zinakekele Medical Centre
  - Witbank (eMalahleni), Mpumalanga, Sør-Afrika, 1035
    - Drs Joynt Venter & Associates
- Western CAPE
  - Cape Town, Western CAPE, Sør-Afrika, 7530
    - Tiervlei Trial Centre
  - Cape Town, Western CAPE, Sør-Afrika, 7130
    - Dr JM Engelbrecht Trial Site-Vergelegen Mediclinic
  - Cape Town, Western CAPE, Sør-Afrika, 7700
    - Synopsis Research cc
  - Somerset West, Western CAPE, Sør-Afrika, 7130
    - Helderberg Research Institute
  - Somerset West, Western CAPE, Sør-Afrika, 7130
    - Synexus Helderberg Clinical Research Centre
Taiwan
- - Kaohsiung, Taiwan, 807
    - Kaohsiung Medical University Chung-Ho Memorial Hospital - New
  - Tainan, Taiwan, 70403
    - National Cheng Kung University Hospital
  - Tainan, Taiwan, 70403
    - National Cheng Kung University (Ncku) Hospital
  - Taipei, Taiwan, 10002
    - National Taiwan University Hospital
  - Taipei, Taiwan, 11217
    - Taipei Veterans General Hospital
  - Taipei, Taiwan, 10449
    - MacKay Memorial Hospital
- Taiwan R O C
  - Taichung, Taiwan R O C, Taiwan, 40447
    - China Medical University Hospital
- Taiwan ROC
  - Taichung, Taiwan ROC, Taiwan, 40201
    - Chung Shan Medical University Hospital
Thailand
- - Bangkok, Thailand, 10400
    - Division Of cardiology,Department of Medicine,Faculty Of Medicine,Chulalongkorn University
- Bangkok
  - Bangkoknoi, Bangkok, Thailand, 10700
    - Division of Cardiology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol
  - Rajathevee, Bangkok, Thailand, 10400
    - Clinical Research Center, Phramongkutklao Hospital
  - Rajathevee, Bangkok, Thailand, 10400
    - Endocrine Unit, Department of Medicine, Phramongkutklao Hospital
  - Ratchathewi, Bangkok, Thailand, 10400
    - Cardiology Unit, Department of Medicine, Faculty of Medicine,Ramathibodi Hospital,Mahidol University
- Khon Kaen
  - Muang, Khon Kaen, Thailand, 40002
    - Division of Cardiology, Department of medicine,Faculty of Medicine, Srinagarind Hospital, Khon Kaen
- Songkhla
  - Hat Yai, Songkhla, Thailand, 90110
    - Division of Cardiology, Department of Medicine, Faculty of Medicine, Songklanagarind Hospital,
- Songkla
  - Hat Yai, Songkla, Thailand, 90110
    - Heart Center, Songklanagarind Prince of Songkla University
Tsjekkia
- - Brno, Tsjekkia, 602 00
    - CCBR Czech Brno, s.r.o.
  - Havirov, Tsjekkia, 73601
    - DIKa centrum s.r.o., Kardiologicka a interni ambulance
  - Hradec Kralove, Tsjekkia, 500 05
    - Fakultni nemocnice Hradec Kralove
  - Hradec Kralove, Tsjekkia, 50005
    - Fakultni nemocnice Hradec Kralove
  - Litovel, Tsjekkia, 784 01
    - Fremlova Apotheca s.r.o.
  - Litovel, Tsjekkia, 784 01
    - Kardio Interna s.r.o.
  - Olomouc, Tsjekkia, 775 20
    - Fakultni Nemocnice Olomouc
  - Pardubice, Tsjekkia, 530 02
    - CCBR Czech a.s.
  - Plzen, Tsjekkia, 326 00
    - Kardiologie Plzen s.r.o.
  - Praha, Tsjekkia, 14059
    - Centrum kardiovaskularni prevence 1. LF UK a TN
  - Praha 10, Tsjekkia, 100 34
    - Fakultni nemocnice Kralovske Vinohrady
  - Praha 2, Tsjekkia, 128 08
    - Fakultní poliklinika Všeobecné fakultní nemocnice v Praze
  - Praha 3, Tsjekkia, 130 00
    - CCBR Czech Prague, s.r.o
  - Praha 5, Tsjekkia, 158 00
    - Kardiologie a interni lekarstvi
  - Praha 6, Tsjekkia, 160 00
    - NEFROMED, s.r.o.
  - Roznov pod Radhostem, Tsjekkia, 756 61
    - Interna a kardiologie s.r.o.
  - Svitavy, Tsjekkia, 568 25
    - Nemocnice Pardubickeho kraje, a.s., Svitavska nemocnice
  - Tabor, Tsjekkia, 390 02
    - Ordinace V Tabacce s.r.o.
  - Uherske Hradiste 1, Tsjekkia, 686 01
    - MUDr. Antonin Dufka, kardiologicka ambulance
  - Uherske Hradiste 1, Tsjekkia, 686 01
    - MUDr. Nina Zemkova s.r.o.
  - Znojmo, Tsjekkia, 66902
    - KIGE s.r.o.
- Jihomoravsky KRAJ
  - Brno, Jihomoravsky KRAJ, Tsjekkia, 638 00
    - Kardiologicka ambulance
- Kralovehradecky KRAJ
  - Broumov, Kralovehradecky KRAJ, Tsjekkia, 55001
    - Edumed s.r.o.
  - Jaromer, Kralovehradecky KRAJ, Tsjekkia, 55101
    - Edumed s.r.o.
  - Trutnov, Kralovehradecky KRAJ, Tsjekkia, 54101
    - Kardiologicka ambulance
  - Trutnov, Kralovehradecky KRAJ, Tsjekkia, 54101
    - Lekarna na Poliklinice
- Moravskoslezsky KRAJ
  - Ostrava, Moravskoslezsky KRAJ, Tsjekkia, 70200
    - MUDr. Jan Vrkoc s.r.o.
- Pardubicky KRAJ
  - Pardubice, Pardubicky KRAJ, Tsjekkia, 53002
    - PV-Kardiologie s.r.o.
Tyrkia
- - Adana, Tyrkia, 01250
    - Baskent University, Adana Yuregir Training & Research Hospital
  - Afyonkarahisar, Tyrkia, 03200
    - A.karahisar Kocatepe Universitesi Hastanesi Ahmet Necdet Sezer Uygulama ve Arastirma Hastanesi
  - Ankara, Tyrkia, 06110
    - Diskapi Yildirim Beyazit Egitim ve Arastirma Hastanesi
  - Antalya, Tyrkia, 07059
    - Akdeniz Universitesi Tip Fakultesi
  - Antalya, Tyrkia, 07058
    - Akdeniz Universitesi Tip Fakultesi Hastanesi
  - Antalya, Tyrkia, 07100
    - Antalya Training & Research Hospital
  - Bursa, Tyrkia, 16320
    - Bursa Yuksek Ihtisas Egitim ve Arastirma Hastanesi
  - Gaziantep, Tyrkia, 27310
    - Gaziantep Universitesi Tip Fakultesi Sahinbey Egitim ve Arastirma Hastanesi
  - Istanbul, Tyrkia, 34093
    - Istanbul Universitesi Istanbul Tip Fakultesi
  - Istanbul, Tyrkia, 34093
    - Bezmialem Vakif Universitesi Tip Fakultesi Kardiyoloji Anabilim Dali
  - Istanbul, Tyrkia, 34093
    - Bezmialem Vakif Universitesi Tip Fakultesi Kardiyoloji Bolumu
  - Istanbul, Tyrkia, 34096
    - Istanbul Universitesi Kardiyoloji Enstitusu
  - Istanbul, Tyrkia, 34752
    - Yeditepe University School of Medicine
  - Izmir, Tyrkia, 35340
    - Dokuz Eylul Universitesi Tip Fakultesi
  - Izmir, Tyrkia, 35100
    - Ege University, School of Medicine
  - Kocaeli, Tyrkia, 41380
    - Kocaeli University School Of Medicine-Kocaeli Universitesi Tip Fakultesi
  - Kutahya, Tyrkia, 43100
    - Dumlupinar Universitesi Kutahya Evliya Celebi EAH
  - Mersin, Tyrkia, 33343
    - Mersin University, School of Medicine
  - Rize, Tyrkia, 53020
    - Recep Tayyip Erdogan University School of Medicine, Training & Research Hospital
- Ankara
  - Izmir, Ankara, Tyrkia, 35340
    - Dokuz Eylul Univesitesi Tip Fakultesi Hastanesi
Tyskland
- - Altenburg, Tyskland, 04600
    - Klinikum Altenburger Land GmbH
  - Bad Homburg, Tyskland, 61348
    - Forschungszentrum Dr. med Irma Schoell
  - Berlin, Tyskland, 13353
    - Deutsches Herzzentrum Berlin
  - Berlin, Tyskland, 12627
    - Synexus Clinical Research GmbH
  - Berlin, Tyskland, 10115
    - Institut fuer Klinische Forschung und Entwicklung(IKFE) Berlin GmbH
  - Berlin, Tyskland, 10117
    - Klinische Forschung Berlin- Mittte GmbH
  - Berlin, Tyskland, 12157
    - POLIKUM Institut GmbH, Polikum Berlin Friedenau
  - Berlin, Tyskland, 12559
    - DRK Kliniken Berlin Kopenick, Zentrum Klinische Forschung
  - Berlin, Tyskland, 13597
    - Medizinisches Versorgungszentrum am Bahnhof Spandau
  - Bielefeld, Tyskland, 33604
    - Staedtische Kliniken Bielefeld Gem. GmbH - Klinikum Mitte
  - Bochum, Tyskland, 44787
    - Synexus Clinical Research GmbH
  - Bochum, Tyskland, 44787
    - Bochum Research Centre-Synexus Clinical Research GmbH
  - Burg-Spreewald, Tyskland, 03096
    - MEDICLIN Reha-Zentrum Spreewald
  - Coburg, Tyskland, 96450
    - Klinikum Coburg
  - Dortmund, Tyskland, 44137
    - St. Johannes-Hospital
  - Dortmund, Tyskland, 44137
    - Kardiologische Praxisgemeinschaft
  - Dortmund, Tyskland, 44141
    - Gemeinschaftspraxis fuer Kardiologie Dres. Med. Willgeroth/Wetzel
  - Dresden, Tyskland, 01069
    - Klinsche Forschung Dresden GmbH
  - Dresden, Tyskland, 01277
    - Praxis Dr. med. Christoph Axthelm
  - Dresden, Tyskland, 01307
    - GWT-TUD GmbH, Studienzentrum Professor Hanefeld
  - Essen, Tyskland, 45355
    - Medizentrum Essen Borbeck
  - Essen, Tyskland, 45355
    - Gemeinschaftspraxis Dr. Hagemann/Breiderhoff/Durfeld
  - Essen, Tyskland, 45355
    - Studienzentrum
  - Essen, Tyskland, 45359
    - Gemeinschaftspraxis Dres. Dirk Weber, Ulrich Weber, Heiner Saueressig, Birte Turner und Georg
  - Falkensee, Tyskland, 14612
    - Schwerpunktpraxis Dr. Luedemann fuer Diabetes Gefaess- und Ernaehrungsmedizin
  - Frankfurt, Tyskland, 60313
    - Synexus Clinical Research GmbH
  - Frankfurt, Tyskland, 60594
    - ClinPhenomics GmbH & Co KG, Studienzentrum
  - Frankfurt am Main, Tyskland, 60596
    - IKF Institut fuer klinische Forschung Frankfurt
  - Greifswald, Tyskland, 17475
    - Klinik und Poliklinik fuer Innere Medizin B - Kardiologie, Angiologie, Pulmologie
  - Hamburg, Tyskland, 22041
    - Cardiologicum Hamburg
  - Hamburg, Tyskland, 22415
    - Praxis Dr. med Cornelia Brauer
  - Hannover, Tyskland, 30159
    - Klinische Forschung Hannover-Mitte GmbH
  - Homburg, Tyskland, 66421
    - Universitaetsklinikum des Saarlandes Klinik fuer Innere Medizin III
  - Kamp-Lintfort, Tyskland, 47475
    - Praxis Dr. Heister
  - Kassel, Tyskland, 34121
    - Studienzentrum Dr. Appel
  - Koeln, Tyskland, 51069
    - Zentrum fuer klinische Forschung
  - Kuenzing, Tyskland, 94550
    - Gemeinschaftspraxis Dr. Klein / Minnich
  - Lahr, Tyskland, 77933
    - Klinik fur Innere Medizin, Kardiologie und Angiologie MediClin Herzzentrum Lahr/Baden.
  - Leipzig, Tyskland, 04249
    - Gemeinschaftspraxis Dr. med. Heidrun Taeschner und Dr. med. Susanne Bonigut
  - Leipzig, Tyskland, 04103
    - Synexus Leipzig Clinical Research Centre
  - Leipzig, Tyskland, 04109
    - SIBAmed Studienzentrum GmbH & Co. KGKG
  - Leverkusen, Tyskland, 51375
    - Klinikum Leverkusen gGmbH
  - Ludwigshafen, Tyskland, 67063
    - Klinikum der Stadt Ludwigshafen am Rhein gGmbH
  - Luedenscheid, Tyskland, 58515
    - Maerkische Kliniken GmbH, Klinikum Luedenscheid, Innere III
  - Lunen, Tyskland, 44534
    - Klinikum Lunen, St. Marienhospital
  - Magdeburg, Tyskland, 39120
    - SMO.MD GmbH, Zentrum fuer klinische Studien Site Management and Clinical Research Unit
  - Mainz, Tyskland, 55116
    - Pfuetzner Science & Health Institute-Gmbh
  - Mannheim, Tyskland, 68165
    - Ze:ro Arztpraxen Dr. med. Salbach
  - Muenchen, Tyskland, 80636
    - Klinikum fuer Herz- & Kreislauferkrankungen
  - Munchen, Tyskland, 80336
    - Klinikum der Universität München
  - Munich, Tyskland, 80636
    - Klinikum Fur Herz- & Kreislauferkrankungen
  - Munich, Tyskland, 81737
    - Staedtisches Klinikum Muenchen GmbH, Klinikum Neuperlach
  - Northeim, Tyskland, 37154
    - Kardiologische Praxis Northeim
  - Nurnberg, Tyskland, 90402
    - Gemeinschaftspraxis Drs Haggenmiller/Jeserich, Kardiologie, Angiologie, Innere Medizin
  - Offenbach, Tyskland, 63071
    - Allgemeinmedizinisch-Internistische Praxisgemeinschaft
  - Rodgau, Tyskland, 63110
    - Praxis Dres. Med Naudts und Nowack
  - Rudersdorf, Tyskland, 15562
    - Klinik Am See - Klinik Am See - Rehabilitationszentrum Fur Innere Medizin
  - Schwerin, Tyskland, 19055
    - Klinische Forschung Schwerin GmbH
  - Soest, Tyskland, 59494
    - Kardiologische Gemeinschaftspraxis Dres Med. Gerke/Buerger
  - Stuhr-Brinkum, Tyskland, 28816
    - Praxisgemeinschaft Stuhr-Brinkum
  - Stuttgart, Tyskland, 70376
    - Robert-Bosch-Krankenhaus
  - Ulm, Tyskland, 89081
    - Universitaetsklinikum Ulm
  - Warendorf, Tyskland, 48231
    - Josephs-Hospital Warendorf Med. Klinik II, Kardiologie/Angiologie
  - Wermsdorf, Tyskland, 04779
    - Kardiologische Praxis
  - Witten, Tyskland, 58455
    - ForschungszentrumRuhr KliFoCenter GmbH
- Baden-wuerttemberg
  - Bad Krozingen, Baden-wuerttemberg, Tyskland, 79189
    - Universitaets Herzzentrum Freiburg Bad Krozingen
- Baden-wurttemberg
  - Heidelberg, Baden-wurttemberg, Tyskland, 69120
    - Medizinische Universitaetsklinik Heidelberg
- Hessen
  - Fulda, Hessen, Tyskland, 36037
    - Gemeinschaftspraxis im Altstadt Carree
- Rheinland Pfalz
  - Neuwied, Rheinland Pfalz, Tyskland, 56564
    - Zentrum Klinische Studien Neuwied (ZKSN)
- Rhineland-palatinate
  - Schwabenheim, Rhineland-palatinate, Tyskland, 55270
    - Gemeinschaftspraxis Schwabenheim
Ungarn
- - Balatonfured, Ungarn, 8230
    - DRC Kft.
  - Balatongyorok, Ungarn, 8313
    - DRC Kft.
  - Bekescsaba, Ungarn, 5600
    - Kardiologiai Maganrendelo
  - Berettyoujfalu, Ungarn, 4100
    - Grof Tisza Istvan Korhaz Berettyoujfalu
  - Budapest, Ungarn, 1088
    - Semmelweis Egyetem
  - Budapest, Ungarn, 1096
    - Gottsegen György Országos Kardiológiai Intézet
  - Budapest, Ungarn, 1036
    - Synexus Magyarorszag Kft
  - Budapest, Ungarn, 1021
    - Budapesti Szent Ferenc Korhaz
  - Budapest, Ungarn, 1106
    - Bajcsy-Zsilinszky Korhaz es Rendelointezet
  - Budapest, Ungarn, 1085
    - Szent Rokus Korhaz
  - Budapest, Ungarn, 1097
    - Egyesitett Szent Istvan es Szent Laszlo Korhaz-Rendelointezet
  - Budapest, Ungarn, 1125
    - Szent Janos Korhaz es Eszak-budai Egyesitett Korhazak, III. Belgyogyaszat-Kardiologiai Osztaly
  - Debrecen, Ungarn, 4032
    - Debreceni Egyetem, I. sz. Belgyogyaszati Klinika
  - Debrecen, Ungarn, 4032
    - Synexus Magyarorszag Egeszsegugyi Szolgaltato Kft.
  - Gyula, Ungarn, 5700
    - Synexus Magyarorszag Kft.
  - Hajduszoboszlo, Ungarn, 4200
    - Edes Szivunk Egeszsegkozpont Kft.
  - Hatvan, Ungarn, 3000
    - BKS Research Kft., Albert Schweitzer Korhaz
  - Kaposvar, Ungarn, 7400
    - Somogy Megyei Kaposi Mór Oktató Kórház
  - Kecskemet, Ungarn, 6000
    - Jutrix Egeszsegugyi Kft
  - Kistarcsa, Ungarn, 2143
    - Pest Megyei Flor Ferenc Korhaz
  - Nyiregyhaza, Ungarn, 4400
    - Medifarma-98 Kft.
  - Nyiregyhaza, Ungarn, 4400
    - Jósa András Oktatókórház
  - Pecs, Ungarn, 7624
    - Pecsi Tudomanyegyetem AOK, I. Belgyogyaszati Klinika
  - Szekesfehervar, Ungarn, 8000
    - Mentahaz Maganorvosi Kozpont
  - Szolnok, Ungarn, 5000
    - Hetényi Géza Kórház
  - Szombathely, Ungarn, 9700
    - Markusovszky Egyetemi Oktatokarhaz
  - Veszprem, Ungarn, 8200
    - Dr. Sydo es Tsa Kft
  - Zalaegerszeg, Ungarn, 8900
    - Zala Megyei Kórház
- Bacs-kiskun
  - Kecskemet, Bacs-kiskun, Ungarn, 6000
    - Bacs-Kiskun Megyei Korhaz
- Baranya
  - Pecs, Baranya, Ungarn, 7624
    - Pecsi Tudomanyegyetem AOK, II.
- Csongrad
  - Szeged, Csongrad, Ungarn, 6720
    - Szegedi Tudomanyegyetem AOK, I. sz Belgyogyaszati Klinika
- Fejer
  - Szekesfehervar, Fejer, Ungarn, 8000
    - Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

14 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Kjønn som er kvalifisert for studier

Alle

Beskrivelse

Inklusjonskriterier:

Må være på bakgrunnslipidsenkende behandling.
Må ha høy risiko for en CV-hendelse.
Må ha en LDL C >/=70 mg/dL (1,8 mmol/L) eller ikke-HDL-C >/= 100 mg/dL (2,6 mmol/L).

Ekskluderingskriterier:

Planlagt koronar (PCI eller CABG) eller annen arteriell revaskularisering.
New York Heart Association klasse IV kongestiv hjertesvikt eller venstre ventrikkel ejeksjonsfraksjon < 25 % ved hjerteavbildning.
Kronisk nyresvikt med kreatininclearance <30 ml/min/1,73m^2 med MDRD-formel eller med slutttilstand nyresykdom på dialyse.
Historie med hemorragisk slag.
Tidligere eksponering for bococizumab eller annen PCSK9-hemmer.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Primært formål: Forebygging
Tildeling: Randomisert
Intervensjonsmodell: Parallell tildeling
Masking: Firemannsrom

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm	Intervensjon / Behandling
Eksperimentell: bococizumab (PF-04950615) 150 mg, hver 2. uke, subkutant	Legemiddel: bococizumab (PF-04950615) 150 mg, hver 2. uke, subkutant. Varigheten av behandlingsperioden vil avhenge av å nå det målrettede antallet bedømte og bekreftede CV-utfallshendelser, ca. 3 til 4 år etter at den første personen deltok i studien. Andre navn: RN316
Placebo komparator: Placebo Placebo komparator, hver 2. uke, subkutant.	Legemiddel: Placebo Placebo komparator, hver 2. uke, subkutant. Varigheten av behandlingsperioden vil avhenge av å nå det målrettede antallet bedømte og bekreftede CV-utfallshendelser, ca. 3 til 4 år etter at den første personen deltok i studien.

Hva måler studien?

Primære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Hendelsesrate per 100 deltaker-år for første forekomst av større kardiovaskulær (CV) hendelse Tidsramme: Fra baseline til datoen for første dømte og bekreftede forekomst av større CV-hendelse (maksimal varighet: opptil 3,4 år)	Hendelsesrate per 100 deltakerår for første forekomst av større CV-hendelse (bedømt av bedømmelseskomiteen) ble rapportert. Major CV-hendelse ble definert som en av følgende: CV-død (definert som plutselig hjertedød, dødelig hjerteinfarkt [MI], død på grunn av hjertesvikt, død på grunn av hjerneslag [fatalt iskemisk hjerneslag eller fatalt hjerneslag med ubestemt etiologi], eller død på grunn av andre kardiovaskulære årsaker) ikke-dødelig hjerteinfarkt, ikke-dødelig hjerneslag og sykehusinnleggelse for ustabil angina som trenger akutt revaskularisering. Hendelsesraten ble beregnet som antall hendelser per 100 deltakerår med risiko.	Fra baseline til datoen for første dømte og bekreftede forekomst av større CV-hendelse (maksimal varighet: opptil 3,4 år)

Sekundære resultatmål

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Pfizer

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Hjelpsomme linker

To obtain contact information for a study center near you, click here.

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Faktiske)

29. oktober 2013

Primær fullføring (Faktiske)

22. mars 2017

Studiet fullført (Faktiske)

22. mars 2017

Datoer for studieregistrering

Først innsendt

21. oktober 2013

Først innsendt som oppfylte QC-kriteriene

28. oktober 2013

Først lagt ut (Anslag)

3. november 2013

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

11. juli 2018

Siste oppdatering sendt inn som oppfylte QC-kriteriene

14. juni 2018

Sist bekreftet

1. juni 2018

Mer informasjon

Begreper knyttet til denne studien

Nøkkelord

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

B1481022
CV OUTCOMES 1
2013-002646-36 (EudraCT-nummer)
CV OUTCOMES 2 (Alias Study Number)

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Studerer et amerikansk FDA-regulert enhetsprodukt

Nei

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

Evalueringen av Bococizumab (PF-04950615;RN316) for å redusere forekomsten av store kardiovaskulære hendelser hos høyrisikopersoner (SPIRE-1)

Fase 3 multisenter, dobbeltblind, randomisert, placebokontrollert, parallell gruppeevaluering av effektiviteten, sikkerheten og toleransen til Bococizumab (Pf-04950615) for å redusere forekomsten av store kardiovaskulære hendelser hos høyrisikopersoner.

Studieoversikt

Status

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

Studietype

Registrering (Faktiske)

Fase

Kontakter og plasseringer

Studiesteder

Deltakelseskriterier

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Tar imot friske frivillige

Kjønn som er kvalifisert for studier

Beskrivelse

Studieplan

Hvordan er studiet utformet?

Designdetaljer

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm

Intervensjon / Behandling

Hva måler studien?

Primære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Samarbeidspartnere og etterforskere

Sponsor

Publikasjoner og nyttige lenker

Generelle publikasjoner

Hjelpsomme linker

Studierekorddatoer

Studer hoveddatoer

Studiestart (Faktiske)

Primær fullføring (Faktiske)

Studiet fullført (Faktiske)

Datoer for studieregistrering

Først innsendt

Først innsendt som oppfylte QC-kriteriene

Først lagt ut (Anslag)

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

Siste oppdatering sendt inn som oppfylte QC-kriteriene

Sist bekreftet

Mer informasjon

Begreper knyttet til denne studien

Nøkkelord

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Studerer et amerikansk FDA-regulert enhetsprodukt