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Durvalumab og Tremelimumab i behandling av pasienter med tilbakevendende stadium IV lungekreft

7. juni 2023 oppdatert av: SWOG Cancer Research Network

En fase II-studie av MEDI4736 (Durvalumab) Pluss Tremelimumab som terapi for pasienter med tidligere behandlet anti-PD-1/PD-L1-resistent stadium IV plateepitel-lungekreft (Lung-Map Non-Match Sub-studie)

Denne fase II-studien studerer hvor godt durvalumab og tremelimumab fungerer i behandling av pasienter med stadium IV lungekreft som har kommet tilbake etter tidligere behandling. Monoklonale antistoffer, som durvalumab og tremelimumab, kan forstyrre tumorcellenes evne til å vokse og spre seg.

Studieoversikt

Status

Fullført

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

PRIMÆRE MÅL:

I. For å evaluere den objektive responsraten (bekreftet og ubekreftet, fullstendig og delvis) etter responsevalueringskriterier i solide svulster (RECIST) 1.1 blant pasienter behandlet med durvalumab (MEDI4736) pluss tremelimumab.

SEKUNDÆRE MÅL:

I. Å estimere varigheten av respons (DoR) blant pasienter som oppnår en fullstendig respons (CR) eller delvis respons (PR) (bekreftet og ubekreftet) av RECIST 1.1.

II. For å estimere varigheten av respons (DoR) per immunrelaterte responskriterier blant pasienter som oppnår en fullstendig respons (CR) eller delvis respons (PR) (bekreftet og ubekreftet) av RECIST 1.1.

III. For å evaluere total overlevelse (OS) blant pasienter behandlet med durvalumab (MEDI4736) pluss tremelimumab.

IV. For å evaluere etterforsker-vurdert progresjonsfri overlevelse (IA-PFS) blant pasienter behandlet med durvalumab (MEDI4736) pluss tremelimumab.

V. Å evaluere IA-PFS vurdert ved immunrelaterte responskriterier (irRC-IA-PFS) blant pasienter behandlet med durvalumab (MEDI4736) pluss tremelimumab.

VI. For å evaluere hyppigheten og alvorlighetsgraden av toksisitet forbundet med durvalumab (MEDI4736) pluss tremelimumab.

TERTIÆRE MÅL:

I. Å utforske sammenhengen mellom potensielle prediktive markører identifisert i S1400A, med respons og progresjonsfri overlevelse (PFS).

II. For å utforske sammenhengen mellom PD-L1-ekspresjonsstatus med respons og PFS.

III. Å bidra til en pågående serum- og tumorbank i S1400.

OVERSIKT:

Pasienter får tremelimumab intravenøst (IV) over 60 minutter på dag 1 for kurs 1-4 og durvalumab IV over 60 minutter på dag 1. Kurs gjentas hver 28. dag i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

Etter avsluttet studiebehandling følges pasientene opp hver 6. måned i 2 år, og deretter ved slutten av år 3.

Studietype

Intervensjonell

Registrering (Faktiske)

Fase

Fase 2

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Forente stater
- Alabama
  - Birmingham, Alabama, Forente stater, 35233
    - University of Alabama at Birmingham Cancer Center
- Alaska
  - Anchorage, Alaska, Forente stater, 98508
    - Anchorage Associates in Radiation Medicine
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Breast Care and Surgery LLC
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Oncology and Hematology LLC
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Women's Cancer Care
  - Anchorage, Alaska, Forente stater, 99508
    - Anchorage Oncology Centre
  - Anchorage, Alaska, Forente stater, 99508
    - Katmai Oncology Group
  - Anchorage, Alaska, Forente stater, 99508
    - Providence Alaska Medical Center
  - Fairbanks, Alaska, Forente stater, 99701
    - Fairbanks Memorial Hospital
- Arizona
  - Tucson, Arizona, Forente stater, 85719
    - University of Arizona Cancer Center-North Campus
  - Tucson, Arizona, Forente stater, 85724
    - The University of Arizona Medical Center-University Campus
- Arkansas
  - Hot Springs, Arkansas, Forente stater, 71913
    - Mercy Cancer Center-Hot Springs
  - Jonesboro, Arkansas, Forente stater, 72401
    - Fowler Family Center for Cancer Care
- California
  - Anaheim, California, Forente stater, 92807
    - Kaiser Permanente-Anaheim
  - Antioch, California, Forente stater, 94531
    - Kaiser Permanente-Deer Valley Medical Center
  - Auburn, California, Forente stater, 95602
    - Sutter Auburn Faith Hospital
  - Auburn, California, Forente stater, 95603
    - Sutter Cancer Centers Radiation Oncology Services-Auburn
  - Bakersfield, California, Forente stater, 93301
    - AIS Cancer Center at San Joaquin Community Hospital
  - Baldwin Park, California, Forente stater, 91706
    - Kaiser Permanente-Baldwin Park
  - Bellflower, California, Forente stater, 90706
    - Kaiser Permanente-Bellflower
  - Berkeley, California, Forente stater, 94704
    - Alta Bates Summit Medical Center-Herrick Campus
  - Burbank, California, Forente stater, 91505
    - Providence Saint Joseph Medical Center/Disney Family Cancer Center
  - Burlingame, California, Forente stater, 94010
    - Mills-Peninsula Medical Center
  - Cameron Park, California, Forente stater, 95682
    - Sutter Cancer Centers Radiation Oncology Services-Cameron Park
  - Castro Valley, California, Forente stater, 94546
    - Eden Hospital Medical Center
  - Corona, California, Forente stater, 92879
    - City of Hope Corona
  - Davis, California, Forente stater, 95616
    - Sutter Davis Hospital
  - Duarte, California, Forente stater, 91010
    - City of Hope Comprehensive Cancer Center
  - Fontana, California, Forente stater, 92335
    - Kaiser Permanente Hospital
  - Fremont, California, Forente stater, 94538
    - Kaiser Permanente-Fremont
  - Fremont, California, Forente stater, 94538
    - Palo Alto Medical Foundation-Fremont
  - Fresno, California, Forente stater, 93720
    - Kaiser Permanente
  - Fullerton, California, Forente stater, 92835
    - Saint Jude Medical Center
  - Harbor City, California, Forente stater, 90710
    - Kaiser Permanente - Harbor City
  - Irvine, California, Forente stater, 92618
    - Kaiser Permanente-Irvine
  - La Jolla, California, Forente stater, 92093
    - UC San Diego Moores Cancer Center
  - Lancaster, California, Forente stater, 93534
    - City of Hope Antelope Valley
  - Los Angeles, California, Forente stater, 90027
    - Kaiser Permanente Los Angeles Medical Center
  - Los Angeles, California, Forente stater, 90034
    - Kaiser Permanente-Cadillac
  - Marysville, California, Forente stater, 95901
    - Fremont - Rideout Cancer Center
  - Mission Hills, California, Forente stater, 91345
    - City of Hope Mission Hills
  - Modesto, California, Forente stater, 95355
    - Memorial Medical Center
  - Modesto, California, Forente stater, 95356
    - Kaiser Permanente-Modesto
  - Mountain View, California, Forente stater, 94040
    - Palo Alto Medical Foundation-Camino Division
  - Mountain View, California, Forente stater, 94040
    - Palo Alto Medical Foundation-Gynecologic Oncology
  - Novato, California, Forente stater, 94945
    - Sutter Cancer Research Consortium
  - Oakland, California, Forente stater, 94611
    - Kaiser Permanente-Oakland
  - Orange, California, Forente stater, 92868
    - Saint Joseph Hospital - Orange
  - Palo Alto, California, Forente stater, 94301
    - Palo Alto Medical Foundation Health Care
  - Panorama City, California, Forente stater, 91402
    - Kaiser Permanente - Panorama City
  - Paradise, California, Forente stater, 95969
    - Feather River Cancer Center
  - Pismo Beach, California, Forente stater, 93449
    - PCR Oncology
  - Rancho Cucamonga, California, Forente stater, 91730
    - City of Hope Rancho Cucamonga
  - Rancho Mirage, California, Forente stater, 92270
    - Eisenhower Medical Center
  - Redwood City, California, Forente stater, 94063
    - Kaiser Permanente-Redwood City
  - Richmond, California, Forente stater, 94801
    - Kaiser Permanente-Richmond
  - Riverside, California, Forente stater, 92505
    - Kaiser Permanente-Riverside
  - Roseville, California, Forente stater, 95661
    - Kaiser Permanente-Roseville
  - Roseville, California, Forente stater, 95661
    - Sutter Cancer Centers Radiation Oncology Services-Roseville
  - Roseville, California, Forente stater, 95661
    - Sutter Roseville Medical Center
  - Sacramento, California, Forente stater, 95816
    - Sutter Medical Center Sacramento
  - Sacramento, California, Forente stater, 95817
    - University of California Davis Comprehensive Cancer Center
  - Sacramento, California, Forente stater, 95823
    - Kaiser Permanente-South Sacramento
  - Sacramento, California, Forente stater, 95825
    - Kaiser Permanente - Sacramento
  - Saint Helena, California, Forente stater, 94574
    - Saint Helena Hospital
  - San Diego, California, Forente stater, 92120
    - Kaiser Permanente-San Diego Zion
  - San Diego, California, Forente stater, 92108
    - Kaiser Permanente-San Diego Mission
  - San Francisco, California, Forente stater, 94115
    - Kaiser Permanente-San Francisco
  - San Francisco, California, Forente stater, 94115
    - California Pacific Medical Center-Pacific Campus
  - San Jose, California, Forente stater, 95119
    - Kaiser Permanente-Santa Teresa-San Jose
  - San Leandro, California, Forente stater, 94577
    - Kaiser Permanente San Leandro
  - San Marcos, California, Forente stater, 92069
    - Kaiser Permanente-San Marcos
  - San Rafael, California, Forente stater, 94903
    - Kaiser Permanente-San Rafael
  - Santa Clara, California, Forente stater, 95051
    - Kaiser Permanente Medical Center - Santa Clara
  - Santa Cruz, California, Forente stater, 95065
    - Palo Alto Medical Foundation-Santa Cruz
  - Santa Rosa, California, Forente stater, 95403
    - Kaiser Permanente-Santa Rosa
  - Santa Rosa, California, Forente stater, 95403
    - Sutter Pacific Medical Foundation
  - South Pasadena, California, Forente stater, 91030
    - City of Hope South Pasadena
  - South San Francisco, California, Forente stater, 94080
    - Kaiser Permanente-South San Francisco
  - Stockton, California, Forente stater, 95210
    - Kaiser Permanente-Stockton
  - Sunnyvale, California, Forente stater, 94086
    - Palo Alto Medical Foundation-Sunnyvale
  - Truckee, California, Forente stater, 96161
    - Gene Upshaw Memorial Tahoe Forest Cancer Center
  - Vacaville, California, Forente stater, 95688
    - Kaiser Permanente Medical Center-Vacaville
  - Vacaville, California, Forente stater, 95687
    - Sutter Cancer Centers Radiation Oncology Services-Vacaville
  - Vallejo, California, Forente stater, 94589
    - Kaiser Permanente-Vallejo
  - Vallejo, California, Forente stater, 94589
    - Sutter Solano Medical Center/Cancer Center
  - Walnut Creek, California, Forente stater, 94596
    - Kaiser Permanente-Walnut Creek
  - Whittier, California, Forente stater, 90602
    - Presbyterian Intercommunity Hospital
  - Woodland Hills, California, Forente stater, 91367
    - Kaiser Permanente
- Colorado
  - Aurora, Colorado, Forente stater, 80045
    - University Of Colorado Hospital
  - Aurora, Colorado, Forente stater, 80012
    - Rocky Mountain Cancer Centers-Aurora
  - Boulder, Colorado, Forente stater, 80301
    - Boulder Community Hospital
  - Boulder, Colorado, Forente stater, 80304
    - Rocky Mountain Cancer Centers-Boulder
  - Colorado Springs, Colorado, Forente stater, 80907
    - Penrose-Saint Francis Healthcare
  - Colorado Springs, Colorado, Forente stater, 80907
    - Rocky Mountain Cancer Centers-Penrose
  - Colorado Springs, Colorado, Forente stater, 80909
    - Memorial Hospital Central
  - Denver, Colorado, Forente stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forente stater, 80205
    - Kaiser Permanente-Franklin
  - Denver, Colorado, Forente stater, 80218
    - Presbyterian - Saint Lukes Medical Center - Health One
  - Denver, Colorado, Forente stater, 80218
    - SCL Health Saint Joseph Hospital
  - Denver, Colorado, Forente stater, 80220
    - Rose Medical Center
  - Denver, Colorado, Forente stater, 80218
    - Rocky Mountain Cancer Centers-Midtown
  - Denver, Colorado, Forente stater, 80220
    - Rocky Mountain Cancer Centers-Rose
  - Denver, Colorado, Forente stater, 80204
    - Denver Health Medical Center
  - Denver, Colorado, Forente stater, 80218
    - Colorado Blood Cancer Institute
  - Denver, Colorado, Forente stater, 80209
    - The Women's Imaging Center
  - Denver, Colorado, Forente stater, 80206
    - National Jewish Health-Main Campus
  - Durango, Colorado, Forente stater, 81301
    - Mercy Medical Center
  - Durango, Colorado, Forente stater, 81301
    - Southwest Oncology PC
  - Englewood, Colorado, Forente stater, 80113
    - Swedish Medical Center
  - Englewood, Colorado, Forente stater, 80113
    - Comprehensive Cancer Care and Research Institute of Colorado LLC
  - Fort Collins, Colorado, Forente stater, 80524
    - Poudre Valley Hospital
  - Golden, Colorado, Forente stater, 80401
    - Mountain Blue Cancer Care Center
  - Golden, Colorado, Forente stater, 80401
    - National Jewish Health-Western Hematology Oncology
  - Greeley, Colorado, Forente stater, 80631
    - North Colorado Medical Center
  - Greenwood Village, Colorado, Forente stater, 80111
    - Rocky Mountain Cancer Centers-Greenwood Village
  - Lafayette, Colorado, Forente stater, 80026
    - Kaiser Permanente-Rock Creek
  - Lakewood, Colorado, Forente stater, 80228
    - Saint Anthony Hospital
  - Lakewood, Colorado, Forente stater, 80228
    - Rocky Mountain Cancer Centers-Lakewood
  - Littleton, Colorado, Forente stater, 80120
    - Rocky Mountain Cancer Centers-Littleton
  - Littleton, Colorado, Forente stater, 80122
    - Littleton Adventist Hospital
  - Lone Tree, Colorado, Forente stater, 80124
    - Kaiser Permanente-Lone Tree
  - Lone Tree, Colorado, Forente stater, 80124
    - Rocky Mountain Cancer Centers-Sky Ridge
  - Longmont, Colorado, Forente stater, 80501
    - Longmont United Hospital
  - Longmont, Colorado, Forente stater, 80501
    - Rocky Mountain Cancer Centers-Longmont
  - Loveland, Colorado, Forente stater, 80539
    - McKee Medical Center
  - Parker, Colorado, Forente stater, 80138
    - Parker Adventist Hospital
  - Parker, Colorado, Forente stater, 80138
    - Rocky Mountain Cancer Centers-Parker
  - Pueblo, Colorado, Forente stater, 81004
    - Saint Mary Corwin Medical Center
  - Pueblo, Colorado, Forente stater, 81008
    - Rocky Mountain Cancer Centers - Pueblo
  - Thornton, Colorado, Forente stater, 80260
    - Rocky Mountain Cancer Centers-Thornton
  - Thornton, Colorado, Forente stater, 80260
    - National Jewish Health-Northern Hematology Oncology
  - Wheat Ridge, Colorado, Forente stater, 80033
    - SCL Health Lutheran Medical Center
- Connecticut
  - Derby, Connecticut, Forente stater, 06418
    - Smilow Cancer Hospital-Derby Care Center
  - Fairfield, Connecticut, Forente stater, 06824
    - Smilow Cancer Hospital Care Center-Fairfield
  - Guilford, Connecticut, Forente stater, 06437
    - Medical Oncology and Hematology Group PC-Guilford
  - Hartford, Connecticut, Forente stater, 06105
    - Smilow Cancer Hospital Care Center at Saint Francis
  - Hartford, Connecticut, Forente stater, 06102
    - Hartford Hospital
  - Meriden, Connecticut, Forente stater, 06451
    - Midstate Medical Center
  - New Britain, Connecticut, Forente stater, 06050
    - The Hospital of Central Connecticut
  - New Haven, Connecticut, Forente stater, 06520
    - Yale University
  - New Haven, Connecticut, Forente stater, 06510
    - Smilow Cancer Center/Yale-New Haven Hospital
  - North Haven, Connecticut, Forente stater, 06473
    - Yale-New Haven Hospital North Haven Medical Center
  - Norwich, Connecticut, Forente stater, 06360
    - Eastern Connecticut Hematology and Oncology Associates
  - Orange, Connecticut, Forente stater, 06477
    - Smilow Cancer Hospital-Orange Care Center
  - Torrington, Connecticut, Forente stater, 06790
    - Charlotte Hungerford Hospital Center for Cancer Care
  - Trumbull, Connecticut, Forente stater, 06611
    - Smilow Cancer Hospital Care Center-Trumbull
  - Waterbury, Connecticut, Forente stater, 06708
    - Smilow Cancer Hospital-Waterbury Care Center
  - Waterford, Connecticut, Forente stater, 06385
    - Lawrence and Memorial Cancer Center
  - West Haven, Connecticut, Forente stater, 06516
    - Veterans Affairs Connecticut Healthcare System-West Haven Campus
- Delaware
  - Lewes, Delaware, Forente stater, 19958
    - Beebe Medical Center
  - Newark, Delaware, Forente stater, 19713
    - Helen F Graham Cancer Center
  - Newark, Delaware, Forente stater, 19713
    - Delaware Clinical and Laboratory Physicians PA
  - Newark, Delaware, Forente stater, 19713
    - Medical Oncology Hematology Consultants PA
  - Newark, Delaware, Forente stater, 19718
    - Christiana Care Health System-Christiana Hospital
  - Newark, Delaware, Forente stater, 19713
    - Regional Hematology and Oncology PA
  - Rehoboth Beach, Delaware, Forente stater, 19971
    - Beebe Health Campus
  - Seaford, Delaware, Forente stater, 19973
    - Nanticoke Memorial Hospital
  - Wilmington, Delaware, Forente stater, 19801
    - Christiana Care Health System-Wilmington Hospital
- District of Columbia
  - Washington, District of Columbia, Forente stater, 20007
    - MedStar Georgetown University Hospital
  - Washington, District of Columbia, Forente stater, 20016
    - Sibley Memorial Hospital
  - Washington, District of Columbia, Forente stater, 20002
    - Kaiser Permanente-Capitol Hill Medical Center
- Florida
  - Aventura, Florida, Forente stater, 33180
    - Mount Sinai Comprehensive Cancer Center at Aventura
  - Coral Gables, Florida, Forente stater, 33146
    - UM Sylvester Comprehensive Cancer Center at Coral Gables
  - Daytona Beach, Florida, Forente stater, 32114
    - Halifax Health Medical Center-Centers for Oncology
  - Deerfield Beach, Florida, Forente stater, 33442
    - UM Sylvester Comprehensive Cancer Center at Deerfield Beach
  - Fort Lauderdale, Florida, Forente stater, 33308
    - Holy Cross Hospital
  - Hollywood, Florida, Forente stater, 33021
    - Memorial Regional Hospital/Joe DiMaggio Children's Hospital
  - Hollywood, Florida, Forente stater, 33021
    - UM Sylvester Comprehensive Cancer Center at Hollywood
  - Miami, Florida, Forente stater, 33136
    - University of Miami Miller School of Medicine-Sylvester Cancer Center
  - Miami Beach, Florida, Forente stater, 33140
    - Mount Sinai Medical Center
  - Pembroke Pines, Florida, Forente stater, 33028
    - Memorial Hospital West
  - Plantation, Florida, Forente stater, 33324
    - UM Sylvester Comprehensive Cancer Center at Plantation
  - Tampa, Florida, Forente stater, 33612
    - Moffitt Cancer Center
- Georgia
  - Albany, Georgia, Forente stater, 31701
    - Phoebe Putney Memorial Hospital
  - Athens, Georgia, Forente stater, 30607
    - University Cancer and Blood Center LLC
  - Atlanta, Georgia, Forente stater, 30308
    - Emory University Hospital Midtown
  - Atlanta, Georgia, Forente stater, 30322
    - Emory University/Winship Cancer Institute
  - Atlanta, Georgia, Forente stater, 30342
    - Northside Hospital
  - Atlanta, Georgia, Forente stater, 30342
    - Saint Joseph's Hospital of Atlanta
  - Augusta, Georgia, Forente stater, 30912
    - Augusta University Medical Center
  - Columbus, Georgia, Forente stater, 31904
    - John B Amos Cancer Center
  - Cumming, Georgia, Forente stater, 30041
    - Northside Hospital-Forsyth
  - Decatur, Georgia, Forente stater, 30033
    - Dekalb Medical Center
  - Gainesville, Georgia, Forente stater, 30501
    - Northeast Georgia Medical Center-Gainesville
  - Lawrenceville, Georgia, Forente stater, 30045
    - Gwinnett Medical Center
  - Macon, Georgia, Forente stater, 31201
    - Medical Center of Central Georgia
  - Macon, Georgia, Forente stater, 31201
    - Central Georgia Gynecologic Oncology
  - Rome, Georgia, Forente stater, 30165
    - Harbin Clinic Medical Oncology and Clinical Research
  - Savannah, Georgia, Forente stater, 31405
    - Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
  - Savannah, Georgia, Forente stater, 31404
    - Memorial University Medical Center
  - Savannah, Georgia, Forente stater, 31404
    - Summit Cancer Care-Memorial
  - Savannah, Georgia, Forente stater, 31405
    - Low Country Cancer Care Associates PC
  - Valdosta, Georgia, Forente stater, 31602
    - South Georgia Medical Center/Pearlman Cancer Center
- Hawaii
  - 'Aiea, Hawaii, Forente stater, 96701
    - Pali Momi Medical Center
  - 'Aiea, Hawaii, Forente stater, 96701
    - Hawaii Oncology Inc-Pali Momi
  - 'Ewa Beach, Hawaii, Forente stater, 96706
    - The Cancer Center of Hawaii-Leeward
  - Honolulu, Hawaii, Forente stater, 96813
    - Queen's Medical Center
  - Honolulu, Hawaii, Forente stater, 96817
    - The Cancer Center of Hawaii-Liliha
  - Honolulu, Hawaii, Forente stater, 96813
    - Straub Clinic and Hospital
  - Honolulu, Hawaii, Forente stater, 96813
    - University of Hawaii Cancer Center
  - Honolulu, Hawaii, Forente stater, 96817
    - Hawaii Cancer Care Inc-Liliha
  - Honolulu, Hawaii, Forente stater, 96817
    - Kuakini Medical Center
  - Honolulu, Hawaii, Forente stater, 96826
    - Kapiolani Medical Center for Women and Children
  - Honolulu, Hawaii, Forente stater, 96813
    - Island Urology
  - Honolulu, Hawaii, Forente stater, 96819
    - Kaiser Permanente Moanalua Medical Center
  - Honolulu, Hawaii, Forente stater, 96813
    - Hawaii Cancer Care Inc-POB II
  - Honolulu, Hawaii, Forente stater, 96813
    - Hawaii Oncology Inc-POB I
  - Honolulu, Hawaii, Forente stater, 96817
    - Hawaii Oncology Inc-Kuakini
  - Lihue, Hawaii, Forente stater, 96766
    - Wilcox Memorial Hospital and Kauai Medical Clinic
- Idaho
  - Boise, Idaho, Forente stater, 83706
    - Saint Alphonsus Cancer Care Center-Boise
  - Boise, Idaho, Forente stater, 83712
    - Saint Luke's Mountain States Tumor Institute
  - Caldwell, Idaho, Forente stater, 83605
    - Saint Alphonsus Cancer Care Center-Caldwell
  - Coeur d'Alene, Idaho, Forente stater, 83814
    - Kootenai Medical Center
  - Emmett, Idaho, Forente stater, 83617
    - Walter Knox Memorial Hospital
  - Fruitland, Idaho, Forente stater, 83619
    - Saint Luke's Mountain States Tumor Institute - Fruitland
  - Meridian, Idaho, Forente stater, 83642
    - Idaho Urologic Institute-Meridian
  - Meridian, Idaho, Forente stater, 83642
    - Saint Luke's Mountain States Tumor Institute - Meridian
  - Nampa, Idaho, Forente stater, 83686
    - Saint Alphonsus Medical Center-Nampa
  - Nampa, Idaho, Forente stater, 83686
    - Saint Luke's Mountain States Tumor Institute - Nampa
  - Post Falls, Idaho, Forente stater, 83854
    - Kootenai Cancer Center
  - Sandpoint, Idaho, Forente stater, 83864
    - Kootenai Cancer Clinic
  - Twin Falls, Idaho, Forente stater, 83301
    - Saint Luke's Mountain States Tumor Institute-Twin Falls
- Illinois
  - Aurora, Illinois, Forente stater, 60504
    - Rush - Copley Medical Center
  - Bloomington, Illinois, Forente stater, 61704
    - Illinois CancerCare-Bloomington
  - Canton, Illinois, Forente stater, 61520
    - Illinois CancerCare-Canton
  - Carbondale, Illinois, Forente stater, 62902
    - Memorial Hospital of Carbondale
  - Carterville, Illinois, Forente stater, 62918
    - SIH Cancer Institute
  - Carthage, Illinois, Forente stater, 62321
    - Illinois CancerCare-Carthage
  - Centralia, Illinois, Forente stater, 62801
    - Centralia Oncology Clinic
  - Chicago, Illinois, Forente stater, 60612
    - Rush University Medical Center
  - Chicago, Illinois, Forente stater, 60637
    - University of Chicago Comprehensive Cancer Center
  - Chicago, Illinois, Forente stater, 60612
    - John H Stroger Jr Hospital of Cook County
  - Chicago, Illinois, Forente stater, 60608
    - Mount Sinai Hospital Medical Center
  - Chicago, Illinois, Forente stater, 60625
    - Swedish Covenant Hospital
  - Danville, Illinois, Forente stater, 61832
    - Carle on Vermilion
  - Decatur, Illinois, Forente stater, 62526
    - Decatur Memorial Hospital
  - Decatur, Illinois, Forente stater, 62526
    - Cancer Care Center of Decatur
  - Effingham, Illinois, Forente stater, 62401
    - Crossroads Cancer Center
  - Effingham, Illinois, Forente stater, 62401
    - Carle Physician Group-Effingham
  - Elk Grove Village, Illinois, Forente stater, 60007
    - AMITA Health Alexian Brothers Medical Center
  - Eureka, Illinois, Forente stater, 61530
    - Illinois CancerCare-Eureka
  - Evanston, Illinois, Forente stater, 60201
    - NorthShore University HealthSystem-Evanston Hospital
  - Evanston, Illinois, Forente stater, 60202
    - Saint Francis Hospital
  - Galesburg, Illinois, Forente stater, 61401
    - Western Illinois Cancer Treatment Center
  - Galesburg, Illinois, Forente stater, 61401
    - Illinois CancerCare-Galesburg
  - Geneva, Illinois, Forente stater, 60134
    - Northwestern Medicine Cancer Center Delnor
  - Glenview, Illinois, Forente stater, 60026
    - NorthShore University HealthSystem-Glenbrook Hospital
  - Harvey, Illinois, Forente stater, 60426
    - Ingalls Memorial Hospital
  - Highland Park, Illinois, Forente stater, 60035
    - NorthShore University HealthSystem-Highland Park Hospital
  - Hinsdale, Illinois, Forente stater, 60521
    - AMITA Health Cancer Institute and Outpatient Center
  - Kewanee, Illinois, Forente stater, 61443
    - Illinois CancerCare-Kewanee Clinic
  - Macomb, Illinois, Forente stater, 61455
    - Illinois CancerCare-Macomb
  - Mattoon, Illinois, Forente stater, 61938
    - Carle Physician Group-Mattoon/Charleston
  - Moline, Illinois, Forente stater, 61265
    - Trinity Medical Center
  - Mount Vernon, Illinois, Forente stater, 62864
    - Good Samaritan Regional Health Center
  - Naperville, Illinois, Forente stater, 60540
    - Hematology Oncology Consultants Limited
  - New Lenox, Illinois, Forente stater, 60451
    - UC Comprehensive Cancer Center at Silver Cross
  - Orland Park, Illinois, Forente stater, 60462
    - University of Chicago Medicine-Orland Park
  - Ottawa, Illinois, Forente stater, 61350
    - Illinois CancerCare-Ottawa Clinic
  - Pekin, Illinois, Forente stater, 61554
    - Illinois CancerCare-Pekin
  - Pekin, Illinois, Forente stater, 61554
    - OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
  - Peoria, Illinois, Forente stater, 61637
    - OSF Saint Francis Medical Center
  - Peoria, Illinois, Forente stater, 61615
    - Illinois CancerCare-Peoria
  - Peoria, Illinois, Forente stater, 61615
    - OSF Saint Francis Radiation Oncology at Peoria Cancer Center
  - Peoria, Illinois, Forente stater, 61603
    - Methodist Medical Center of Illinois
  - Peru, Illinois, Forente stater, 61354
    - Illinois CancerCare-Peru
  - Peru, Illinois, Forente stater, 61354
    - Valley Radiation Oncology
  - Princeton, Illinois, Forente stater, 61356
    - Illinois CancerCare-Princeton
  - Skokie, Illinois, Forente stater, 60076
    - North Shore Medical Center
  - Springfield, Illinois, Forente stater, 62781
    - Memorial Medical Center
  - Springfield, Illinois, Forente stater, 62702
    - Southern Illinois University School of Medicine
  - Springfield, Illinois, Forente stater, 62702
    - Springfield Clinic
  - Swansea, Illinois, Forente stater, 62226
    - Cancer Care Specialists of Illinois-Swansea
  - Swansea, Illinois, Forente stater, 62226
    - Memorial and Saint Elizabeth's Health Care Services LLP
  - Urbana, Illinois, Forente stater, 61801
    - Carle Cancer Center
  - Urbana, Illinois, Forente stater, 61801
    - The Carle Foundation Hospital
  - Warrenville, Illinois, Forente stater, 60555
    - Northwestern Medicine Cancer Center Warrenville
  - Yorkville, Illinois, Forente stater, 60560
    - Rush-Copley Healthcare Center
- Indiana
  - Carmel, Indiana, Forente stater, 46032
    - IU Health North Hospital
  - Evansville, Indiana, Forente stater, 47713
    - Deaconess Clinic Downtown
  - Indianapolis, Indiana, Forente stater, 46237
    - Franciscan Health Indianapolis
  - Indianapolis, Indiana, Forente stater, 46202
    - Indiana University/Melvin and Bren Simon Cancer Center
  - Indianapolis, Indiana, Forente stater, 46202
    - Sidney and Lois Eskenazi Hospital
  - Indianapolis, Indiana, Forente stater, 46202
    - Richard L. Roudebush Veterans Affairs Medical Center
  - Indianapolis, Indiana, Forente stater, 46290
    - Springmill Medical Center
  - Indianapolis, Indiana, Forente stater, 46202
    - IU Health Methodist Hospital
  - Michigan City, Indiana, Forente stater, 46360
    - Franciscan Saint Anthony Health-Michigan City
  - Michigan City, Indiana, Forente stater, 46360
    - Woodland Cancer Care Center
  - Mishawaka, Indiana, Forente stater, 46545
    - Memorial Regional Cancer Center Day Road
  - Mooresville, Indiana, Forente stater, 46158
    - Franciscan Health Mooresville
  - Munster, Indiana, Forente stater, 46321
    - The Community Hospital
  - Newburgh, Indiana, Forente stater, 47630
    - Chancellor Center for Oncology
  - Richmond, Indiana, Forente stater, 47374
    - Reid Health
  - South Bend, Indiana, Forente stater, 46601
    - Memorial Hospital of South Bend
  - Terre Haute, Indiana, Forente stater, 47804
    - Union Hospital
- Iowa
  - Clive, Iowa, Forente stater, 50325
    - Mercy Cancer Center-West Lakes
  - Clive, Iowa, Forente stater, 50325
    - Medical Oncology and Hematology Associates-West Des Moines
  - Council Bluffs, Iowa, Forente stater, 51503
    - Alegent Health Mercy Hospital
  - Creston, Iowa, Forente stater, 50801
    - Greater Regional Medical Center
  - Des Moines, Iowa, Forente stater, 50309
    - Iowa Methodist Medical Center
  - Des Moines, Iowa, Forente stater, 50314
    - Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forente stater, 50309
    - Medical Oncology and Hematology Associates-Des Moines
  - Des Moines, Iowa, Forente stater, 50314
    - Broadlawns Medical Center
  - Des Moines, Iowa, Forente stater, 50316
    - Iowa Lutheran Hospital
  - Des Moines, Iowa, Forente stater, 50314
    - Medical Oncology and Hematology Associates-Laurel
  - Fairfield, Iowa, Forente stater, 52556
    - JCHC McCreery Cancer Center
  - Ottumwa, Iowa, Forente stater, 52501
    - Ottumwa Regional Health Center
  - Waterloo, Iowa, Forente stater, 50702
    - Covenant Medical Center
  - West Des Moines, Iowa, Forente stater, 50266-7700
    - Methodist West Hospital
  - West Des Moines, Iowa, Forente stater, 50266
    - Mercy Medical Center-West Lakes
- Kansas
  - Chanute, Kansas, Forente stater, 66720
    - Cancer Center of Kansas - Chanute
  - Dodge City, Kansas, Forente stater, 67801
    - Cancer Center of Kansas - Dodge City
  - El Dorado, Kansas, Forente stater, 67042
    - Cancer Center of Kansas - El Dorado
  - Emporia, Kansas, Forente stater, 66801
    - Newman Regional Health
  - Fort Scott, Kansas, Forente stater, 66701
    - Cancer Center of Kansas - Fort Scott
  - Garden City, Kansas, Forente stater, 67846
    - Saint Catherine Hospital
  - Great Bend, Kansas, Forente stater, 67530
    - Heartland Cancer Center
  - Hays, Kansas, Forente stater, 67601
    - Hays Medical Center
  - Independence, Kansas, Forente stater, 67301
    - Cancer Center of Kansas-Independence
  - Kansas City, Kansas, Forente stater, 66160
    - University of Kansas Cancer Center
  - Kansas City, Kansas, Forente stater, 66112
    - University of Kansas Cancer Center-West
  - Kingman, Kansas, Forente stater, 67068
    - Cancer Center of Kansas-Kingman
  - Lawrence, Kansas, Forente stater, 66044
    - Lawrence Memorial Hospital
  - Liberal, Kansas, Forente stater, 67905
    - Cancer Center of Kansas-Liberal
  - Manhattan, Kansas, Forente stater, 66502
    - Cancer Center of Kansas-Manhattan
  - McPherson, Kansas, Forente stater, 67460
    - Cancer Center of Kansas - McPherson
  - Newton, Kansas, Forente stater, 67114
    - Cancer Center of Kansas - Newton
  - Olathe, Kansas, Forente stater, 66061
    - Olathe Medical Center
  - Overland Park, Kansas, Forente stater, 66210
    - University of Kansas Cancer Center-Overland Park
  - Parsons, Kansas, Forente stater, 67357
    - Cancer Center of Kansas - Parsons
  - Pittsburg, Kansas, Forente stater, 66762
    - Via Christi Hospital-Pittsburg
  - Pratt, Kansas, Forente stater, 67124
    - Cancer Center of Kansas - Pratt
  - Salina, Kansas, Forente stater, 67401
    - Salina Regional Health Center
  - Salina, Kansas, Forente stater, 67401
    - Cancer Center of Kansas - Salina
  - Topeka, Kansas, Forente stater, 66606
    - Cotton O'Neil Cancer Center / Stormont Vail Health
  - Topeka, Kansas, Forente stater, 66606
    - Saint Francis Hospital and Medical Center - Topeka
  - Wellington, Kansas, Forente stater, 67152
    - Cancer Center of Kansas - Wellington
  - Westwood, Kansas, Forente stater, 66205
    - University of Kansas Hospital-Westwood Cancer Center
  - Wichita, Kansas, Forente stater, 67208
    - Cancer Center of Kansas-Wichita Medical Arts Tower
  - Wichita, Kansas, Forente stater, 67214
    - Cancer Center of Kansas - Wichita
  - Wichita, Kansas, Forente stater, 67208
    - Associates In Womens Health
  - Wichita, Kansas, Forente stater, 67214
    - Via Christi Regional Medical Center
  - Winfield, Kansas, Forente stater, 67156
    - Cancer Center of Kansas - Winfield
- Kentucky
  - Ashland, Kentucky, Forente stater, 41101
    - King's Daughter's Medical Center
  - Bardstown, Kentucky, Forente stater, 40004
    - Flaget Memorial Hospital
  - Corbin, Kentucky, Forente stater, 40701
    - Baptist Health Corbin
  - Corbin, Kentucky, Forente stater, 40701
    - Commonwealth Cancer Center-Corbin
  - Elizabethtown, Kentucky, Forente stater, 42701
    - Hardin Memorial Hospital
  - Lexington, Kentucky, Forente stater, 40536
    - University of Kentucky/Markey Cancer Center
  - Lexington, Kentucky, Forente stater, 40504
    - Saint Joseph Radiation Oncology Resource Center
  - Lexington, Kentucky, Forente stater, 40509
    - Saint Joseph Hospital East
  - Lexington, Kentucky, Forente stater, 40503
    - Baptist Health Lexington
  - Louisville, Kentucky, Forente stater, 40202
    - Jewish Hospital
  - Louisville, Kentucky, Forente stater, 40207
    - Baptist Health Louisville
  - Louisville, Kentucky, Forente stater, 40215
    - Saints Mary and Elizabeth Hospital
  - Louisville, Kentucky, Forente stater, 40245
    - Jewish Hospital Medical Center Northeast
  - Madisonville, Kentucky, Forente stater, 42431
    - Baptist Health Madisonville/Merle Mahr Cancer Center
  - Paducah, Kentucky, Forente stater, 42003
    - Baptist Health Paducah
  - Shepherdsville, Kentucky, Forente stater, 40165
    - Jewish Hospital Medical Center South
- Louisiana
  - Baton Rouge, Louisiana, Forente stater, 70805
    - LSU Health Baton Rouge-North Clinic
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Louisiana Hematology Oncology Associates LLC
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Mary Bird Perkins Cancer Center
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Ochsner Health Center-Summa
  - Baton Rouge, Louisiana, Forente stater, 70806
    - Baton Rouge General Medical Center
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Hematology/Oncology Clinic LLP
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Medical Oncology LLC
  - Covington, Louisiana, Forente stater, 70433
    - Mary Bird Cancer Center/Saint Tammany Parish
  - Covington, Louisiana, Forente stater, 70433
    - North Shore Hematology Oncology Associates Inc
  - Houma, Louisiana, Forente stater, 70360
    - Mary Bird Perkins Cancer Center/Terrebonne General Medical Center
  - Houma, Louisiana, Forente stater, 70360
    - Oncology Center of The South Incorporated
  - Kenner, Louisiana, Forente stater, 70065
    - Ochsner Medical Center Kenner
  - Metairie, Louisiana, Forente stater, 70006
    - East Jefferson General Hospital
  - Metairie, Louisiana, Forente stater, 70006
    - Robert Veith MD LLC
  - New Orleans, Louisiana, Forente stater, 70121
    - Ochsner Medical Center Jefferson
  - New Orleans, Louisiana, Forente stater, 70112
    - Tulane University Health Sciences Center
  - New Orleans, Louisiana, Forente stater, 70112
    - University Medical Center New Orleans
  - New Orleans, Louisiana, Forente stater, 70112
    - Louisiana State University Health Science Center
  - New Orleans, Louisiana, Forente stater, 70115
    - LSU Healthcare Network/Saint Charles
- Maine
  - Augusta, Maine, Forente stater, 04330
    - Harold Alfond Center for Cancer Care
  - Bangor, Maine, Forente stater, 04401
    - Eastern Maine Medical Center
  - Brewer, Maine, Forente stater, 04412
    - Lafayette Family Cancer Center-EMMC
  - Portland, Maine, Forente stater, 04101
    - Mercy Hospital
  - Rockport, Maine, Forente stater, 04856
    - Penobscot Bay Medical Center
- Maryland
  - Baltimore, Maryland, Forente stater, 21237
    - MedStar Franklin Square Medical Center/Weinberg Cancer Institute
  - Baltimore, Maryland, Forente stater, 21287
    - Johns Hopkins University/Sidney Kimmel Cancer Center
  - Baltimore, Maryland, Forente stater, 21215
    - Sinai Hospital of Baltimore
  - Baltimore, Maryland, Forente stater, 21204
    - Greater Baltimore Medical Center
  - Baltimore, Maryland, Forente stater, 21201
    - University of Maryland/Greenebaum Cancer Center
  - Baltimore, Maryland, Forente stater, 21218
    - MedStar Union Memorial Hospital
  - Baltimore, Maryland, Forente stater, 21229
    - Saint Agnes Hospital
  - Baltimore, Maryland, Forente stater, 21244
    - Kaiser Permanente-Woodlawn Medical Center
  - Bel Air, Maryland, Forente stater, 21014
    - Upper Chesapeake Medical Center
  - Cumberland, Maryland, Forente stater, 21502
    - Western Maryland Regional Medical Center
  - Frederick, Maryland, Forente stater, 21701
    - Frederick Memorial Hospital
  - Gaithersburg, Maryland, Forente stater, 20879
    - Kaiser Permanente-Gaithersburg Medical Center
  - Kensington, Maryland, Forente stater, 20895
    - Kaiser Permanente - Kensington Medical Center
  - Largo, Maryland, Forente stater, 20774
    - Kaiser Permanente - Largo Medical Center
  - Olney, Maryland, Forente stater, 20832
    - Montgomery General Hospital-Olney
  - Randallstown, Maryland, Forente stater, 21133
    - Northwest Hospital Center
  - Salisbury, Maryland, Forente stater, 21801
    - Peninsula Regional Medical Center
  - Westminster, Maryland, Forente stater, 21157
    - William E Kahlert Regional Cancer Center/Sinai Hospital
- Massachusetts
  - Boston, Massachusetts, Forente stater, 02118
    - Boston Medical Center
  - Burlington, Massachusetts, Forente stater, 01805
    - Lahey Hospital and Medical Center
  - Fitchburg, Massachusetts, Forente stater, 01420
    - Simonds-Sinon Regional Cancer Center
  - Lowell, Massachusetts, Forente stater, 01854
    - Lowell General Hospital
  - Winchester, Massachusetts, Forente stater, 01890
    - Winchester Hospital
  - Worcester, Massachusetts, Forente stater, 01655
    - University of Massachusetts Medical School
- Michigan
  - Ann Arbor, Michigan, Forente stater, 48106-0995
    - Saint Joseph Mercy Hospital
  - Ann Arbor, Michigan, Forente stater, 48109
    - University Of Michigan Comprehensive Cancer Center
  - Battle Creek, Michigan, Forente stater, 49017
    - Bronson Battle Creek
  - Brighton, Michigan, Forente stater, 48114
    - Saint Joseph Mercy Brighton
  - Brighton, Michigan, Forente stater, 48114
    - IHA Hematology Oncology Consultants-Brighton
  - Brownstown, Michigan, Forente stater, 48183
    - Henry Ford Cancer Institute?Downriver
  - Canton, Michigan, Forente stater, 48188
    - IHA Hematology Oncology Consultants-Canton
  - Canton, Michigan, Forente stater, 48188
    - Saint Joseph Mercy Canton Health Center
  - Caro, Michigan, Forente stater, 48723
    - Caro Cancer Center
  - Chelsea, Michigan, Forente stater, 48118
    - Saint Joseph Mercy Chelsea
  - Chelsea, Michigan, Forente stater, 48118
    - IHA Hematology Oncology Consultants-Chelsea
  - Clarkston, Michigan, Forente stater, 48346
    - Hematology Oncology Consultants-Clarkston
  - Clarkston, Michigan, Forente stater, 48346
    - Newland Medical Associates-Clarkston
  - Clinton Township, Michigan, Forente stater, 48038
    - Henry Ford Macomb Hospital-Clinton Township
  - Dearborn, Michigan, Forente stater, 48126
    - Henry Ford Medical Center-Fairlane
  - Dearborn, Michigan, Forente stater, 48124
    - Beaumont Hospital-Dearborn
  - Detroit, Michigan, Forente stater, 48202
    - Henry Ford Hospital
  - Detroit, Michigan, Forente stater, 48236
    - Saint John Hospital and Medical Center
  - Detroit, Michigan, Forente stater, 48201
    - Wayne State University/Karmanos Cancer Institute
  - East China Township, Michigan, Forente stater, 48054
    - Great Lakes Cancer Management Specialists-Doctors Park
  - Escanaba, Michigan, Forente stater, 49829
    - Green Bay Oncology - Escanaba
  - Farmington, Michigan, Forente stater, 48334
    - Botsford General Hospital
  - Farmington Hills, Michigan, Forente stater, 48334
    - Weisberg Cancer Treatment Center
  - Flint, Michigan, Forente stater, 48502
    - Hurley Medical Center
  - Flint, Michigan, Forente stater, 48503
    - Genesee Cancer and Blood Disease Treatment Center
  - Flint, Michigan, Forente stater, 48503
    - Genesee Hematology Oncology PC
  - Flint, Michigan, Forente stater, 48503
    - Genesys Hurley Cancer Institute
  - Grand Rapids, Michigan, Forente stater, 49503
    - Spectrum Health at Butterworth Campus
  - Grand Rapids, Michigan, Forente stater, 49503
    - Mercy Health Saint Mary's
  - Grosse Pointe, Michigan, Forente stater, 48230
    - William Beaumont Hospital-Grosse Point
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Michigan Breast Specialists-Grosse Pointe Woods
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Lymphoma Clinic of Michigan
  - Jackson, Michigan, Forente stater, 49201
    - Allegiance Health
  - Kalamazoo, Michigan, Forente stater, 49007
    - West Michigan Cancer Center
  - Kalamazoo, Michigan, Forente stater, 49001
    - Borgess Medical Center
  - Lansing, Michigan, Forente stater, 48912
    - Sparrow Hospital
  - Livonia, Michigan, Forente stater, 48154
    - Saint Mary Mercy Hospital
  - Livonia, Michigan, Forente stater, 48154
    - Hope Cancer Clinic
  - Macomb, Michigan, Forente stater, 48044
    - Michigan Breast Specialists-Macomb Township
  - Macomb, Michigan, Forente stater, 48044
    - Hematology Oncology Associates East PC
  - Midland, Michigan, Forente stater, 48670
    - Mid-Michigan Medical Center - Midland
  - Monroe, Michigan, Forente stater, 48162
    - Monroe Cancer Center
  - Muskegon, Michigan, Forente stater, 49444
    - Mercy Health Mercy Campus
  - Niles, Michigan, Forente stater, 49120
    - Lakeland Community Hospital
  - Novi, Michigan, Forente stater, 48377
    - Henry Ford Medical Center-Columbus
  - Novi, Michigan, Forente stater, 48374-1236
    - Assarian Cancer Center
  - Pontiac, Michigan, Forente stater, 48341
    - Saint Joseph Mercy Oakland
  - Pontiac, Michigan, Forente stater, 48341
    - 21st Century Oncology-Pontiac
  - Pontiac, Michigan, Forente stater, 48341
    - Hope Cancer Center
  - Pontiac, Michigan, Forente stater, 48341
    - Newland Medical Associates-Pontiac
  - Port Huron, Michigan, Forente stater, 48060
    - Lake Huron Medical Center
  - Reed City, Michigan, Forente stater, 49677
    - Spectrum Health Reed City Hospital
  - Rochester Hills, Michigan, Forente stater, 48309
    - Great Lakes Cancer Management Specialists-Rochester Hills
  - Roseville, Michigan, Forente stater, 48066
    - Michigan Cancer Specialists
  - Royal Oak, Michigan, Forente stater, 48073
    - William Beaumont Hospital-Royal Oak
  - Royal Oak, Michigan, Forente stater, 48067
    - Oakland Colon and Rectal Association
  - Royal Oak, Michigan, Forente stater, 48073
    - Cancer Care Associates PC
  - Royal Oak, Michigan, Forente stater, 48073
    - Comprehensive Medical Center PLLC
  - Royal Oak, Michigan, Forente stater, 48073
    - Hematology Oncology Consultants PC
  - Royal Oak, Michigan, Forente stater, 48073
    - Oakland Medical Group
  - Saginaw, Michigan, Forente stater, 48601
    - Saint Mary's of Michigan
  - Saginaw, Michigan, Forente stater, 48604
    - Oncology Hematology Associates of Saginaw Valley PC
  - Saint Joseph, Michigan, Forente stater, 49085
    - Marie Yeager Cancer Center
  - Saint Joseph, Michigan, Forente stater, 49085
    - Lakeland Hospital
  - Southfield, Michigan, Forente stater, 48075
    - Providence Hospital-Southfield Cancer Center
  - Sterling Heights, Michigan, Forente stater, 48312
    - Bhadresh Nayak MD PC-Sterling Heights
  - Sterling Heights, Michigan, Forente stater, 48312
    - Premier Hematology Oncology Care
  - Sterling Heights, Michigan, Forente stater, 48314
    - Mitchell Folbe MD PC
  - Traverse City, Michigan, Forente stater, 49684
    - Munson Medical Center
  - Troy, Michigan, Forente stater, 48098
    - William Beaumont Hospital - Troy
  - Troy, Michigan, Forente stater, 48084
    - Michigan Institute of Urology-Town Center
  - Troy, Michigan, Forente stater, 48085
    - Claudia BR Herke MD PC
  - Troy, Michigan, Forente stater, 48098
    - Hematology Oncology Consultants PC-Troy
  - Warren, Michigan, Forente stater, 48093
    - Saint John Macomb-Oakland Hospital
  - Warren, Michigan, Forente stater, 48093
    - Great Lakes Cancer Management Specialists-Macomb Professional Building
  - Warren, Michigan, Forente stater, 48093
    - Macomb Hematology Oncology PC
  - Warren, Michigan, Forente stater, 48093
    - Michigan Breast Specialists-Warren
  - West Bloomfield, Michigan, Forente stater, 48322
    - Henry Ford West Bloomfield Hospital
  - West Branch, Michigan, Forente stater, 48661
    - Saint Mary's Oncology/Hematology Associates of West Branch
  - Wyoming, Michigan, Forente stater, 49519
    - Metro Health Hospital
  - Ypsilanti, Michigan, Forente stater, 48106
    - Huron Gastroenterology PC
  - Ypsilanti, Michigan, Forente stater, 48197
    - IHA Hematology Oncology Consultants-Ann Arbor
- Minnesota
  - Bemidji, Minnesota, Forente stater, 56601
    - Sanford Clinic North-Bemidgi
  - Brainerd, Minnesota, Forente stater, 56401
    - Essentia Health Saint Joseph's Medical Center
  - Burnsville, Minnesota, Forente stater, 55337
    - Fairview Ridges Hospital
  - Coon Rapids, Minnesota, Forente stater, 55433
    - Mercy Hospital
  - Duluth, Minnesota, Forente stater, 55805
    - Essentia Health Cancer Center
  - Duluth, Minnesota, Forente stater, 55805
    - Essentia Health Saint Mary's Medical Center
  - Duluth, Minnesota, Forente stater, 55805
    - Miller-Dwan Hospital
  - Edina, Minnesota, Forente stater, 55435
    - Fairview-Southdale Hospital
  - Fergus Falls, Minnesota, Forente stater, 56537
    - Lake Region Healthcare Corporation-Cancer Care
  - Fridley, Minnesota, Forente stater, 55432
    - Unity Hospital
  - Maple Grove, Minnesota, Forente stater, 55369
    - Fairview Maple Grove Medical Center
  - Maplewood, Minnesota, Forente stater, 55109
    - Saint John's Hospital - Healtheast
  - Maplewood, Minnesota, Forente stater, 55109
    - Minnesota Oncology Hematology PA-Maplewood
  - Minneapolis, Minnesota, Forente stater, 55415
    - Hennepin County Medical Center
  - Minneapolis, Minnesota, Forente stater, 55407
    - Abbott-Northwestern Hospital
  - Minneapolis, Minnesota, Forente stater, 55454
    - Health Partners Inc
  - New Ulm, Minnesota, Forente stater, 56073
    - New Ulm Medical Center
  - Robbinsdale, Minnesota, Forente stater, 55422
    - North Memorial Medical Health Center
  - Saint Louis Park, Minnesota, Forente stater, 55416
    - Park Nicollet Clinic - Saint Louis Park
  - Saint Paul, Minnesota, Forente stater, 55101
    - Regions Hospital
  - Saint Paul, Minnesota, Forente stater, 55102
    - United Hospital
  - Shakopee, Minnesota, Forente stater, 55379
    - Saint Francis Regional Medical Center
  - Stillwater, Minnesota, Forente stater, 55082
    - Lakeview Hospital
  - Waconia, Minnesota, Forente stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forente stater, 56201
    - Rice Memorial Hospital
  - Woodbury, Minnesota, Forente stater, 55125
    - Minnesota Oncology Hematology PA-Woodbury
  - Wyoming, Minnesota, Forente stater, 55092
    - Fairview Lakes Medical Center
- Mississippi
  - Columbus, Mississippi, Forente stater, 39705
    - Baptist Cancer Center-Golden Triangle
  - Grenada, Mississippi, Forente stater, 38901
    - Boston Baskin Cancer Center-Grenada
  - Jackson, Mississippi, Forente stater, 39216
    - University of Mississippi Medical Center
  - Oxford, Mississippi, Forente stater, 38655
    - Family Cancer Center-Oxford
  - Pascagoula, Mississippi, Forente stater, 39581
    - Singing River Hospital
  - Southhaven, Mississippi, Forente stater, 38671
    - Baptist Memorial Hospital-DeSoto
- Missouri
  - Ballwin, Missouri, Forente stater, 63011
    - Saint Louis Cancer and Breast Institute-Ballwin
  - Bolivar, Missouri, Forente stater, 65613
    - Central Care Cancer Center-Carrie J Babb Cancer Center
  - Bonne Terre, Missouri, Forente stater, 63628
    - Parkland Health Center-Bonne Terre
  - Branson, Missouri, Forente stater, 65616
    - CoxHealth Cancer Center
  - Cape Girardeau, Missouri, Forente stater, 63703
    - Saint Francis Medical Center
  - Cape Girardeau, Missouri, Forente stater, 63703
    - Southeast Cancer Center
  - Columbia, Missouri, Forente stater, 65212
    - University of Missouri - Ellis Fischel
  - Creve Coeur, Missouri, Forente stater, 63141
    - Siteman Cancer Center at West County Hospital
  - Jefferson City, Missouri, Forente stater, 65109
    - Capital Region Medical Center-Goldschmidt Cancer Center
  - Joplin, Missouri, Forente stater, 64804
    - Freeman Health System
  - Joplin, Missouri, Forente stater, 64804
    - Mercy Hospital-Joplin
  - Kansas City, Missouri, Forente stater, 64131
    - The University of Kansas Cancer Center-South
  - Kansas City, Missouri, Forente stater, 64108
    - Truman Medical Center
  - Kansas City, Missouri, Forente stater, 64154
    - The University of Kansas Cancer Center-North
  - Lee's Summit, Missouri, Forente stater, 64064
    - The University of Kansas Cancer Center-Lee's Summit
  - Rolla, Missouri, Forente stater, 65401
    - Delbert Day Cancer Institute at PCRMC
  - Rolla, Missouri, Forente stater, 65401
    - Saint John's Clinic-Rolla-Cancer and Hematology
  - Saint Joseph, Missouri, Forente stater, 64506
    - Heartland Regional Medical Center
  - Saint Louis, Missouri, Forente stater, 63110
    - Washington University School of Medicine
  - Saint Louis, Missouri, Forente stater, 63131
    - Missouri Baptist Medical Center
  - Saint Louis, Missouri, Forente stater, 63141
    - Mercy Hospital Saint Louis
  - Saint Louis, Missouri, Forente stater, 63129
    - Siteman Cancer Center-South County
  - Saint Louis, Missouri, Forente stater, 63109
    - Saint Louis Cancer and Breast Institute-South City
  - Saint Louis, Missouri, Forente stater, 63136
    - Christian Hospital
  - Saint Peters, Missouri, Forente stater, 63376
    - Siteman Cancer Center at Saint Peters Hospital
  - Sainte Genevieve, Missouri, Forente stater, 63670
    - Sainte Genevieve County Memorial Hospital
  - Springfield, Missouri, Forente stater, 65807
    - CoxHealth South Hospital
  - Springfield, Missouri, Forente stater, 65804
    - Mercy Hospital Springfield
  - Sullivan, Missouri, Forente stater, 63080
    - Missouri Baptist Sullivan Hospital
  - Sunset Hills, Missouri, Forente stater, 63127
    - Missouri Baptist Outpatient Center-Sunset Hills
  - Washington, Missouri, Forente stater, 63090
    - Mercy Hospital Washington
- Montana
  - Anaconda, Montana, Forente stater, 59711
    - Community Hospital of Anaconda
  - Billings, Montana, Forente stater, 59101
    - Billings Clinic Cancer Center
  - Bozeman, Montana, Forente stater, 59715
    - Bozeman Deaconess Hospital
  - Great Falls, Montana, Forente stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forente stater, 59405
    - Benefis Healthcare- Sletten Cancer Institute
  - Helena, Montana, Forente stater, 59601
    - Saint Peter's Community Hospital
  - Kalispell, Montana, Forente stater, 59901
    - Kalispell Regional Medical Center
  - Missoula, Montana, Forente stater, 59804
    - Community Medical Hospital
  - Missoula, Montana, Forente stater, 59802
    - Saint Patrick Hospital - Community Hospital
- Nebraska
  - Grand Island, Nebraska, Forente stater, 68803
    - CHI Health Saint Francis
  - Kearney, Nebraska, Forente stater, 68847
    - CHI Health Good Samaritan
  - Kearney, Nebraska, Forente stater, 68845
    - Heartland Hematology and Oncology
  - Lincoln, Nebraska, Forente stater, 68506
    - Nebraska Hematology and Oncology
  - Lincoln, Nebraska, Forente stater, 68510
    - Nebraska Cancer Research Center
  - Lincoln, Nebraska, Forente stater, 68510
    - Saint Elizabeth Regional Medical Center
  - Lincoln, Nebraska, Forente stater, 68510
    - Southeast Nebraska Cancer Center
  - Norfolk, Nebraska, Forente stater, 68701
    - Faith Regional Medical Offices West
  - North Platte, Nebraska, Forente stater, 69103
    - Great Plains Regional Medical Center
  - Omaha, Nebraska, Forente stater, 68114
    - Nebraska Methodist Hospital
  - Omaha, Nebraska, Forente stater, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forente stater, 68124
    - Alegent Health Bergan Mercy Medical Center
  - Omaha, Nebraska, Forente stater, 68122
    - Alegent Health Immanuel Medical Center
  - Omaha, Nebraska, Forente stater, 68130
    - Alegent Health Lakeside Hospital
  - Omaha, Nebraska, Forente stater, 68131
    - Creighton University Medical Center
  - Omaha, Nebraska, Forente stater, 68130
    - Oncology Hematology West PC
  - Omaha, Nebraska, Forente stater, 68122
    - Hemotology and Oncology Consultants PC
  - Omaha, Nebraska, Forente stater, 68124
    - Oncology Hematology West
  - Papillion, Nebraska, Forente stater, 68046
    - Midlands Community Hospital
  - Scottsbluff, Nebraska, Forente stater, 69361
    - Regional West Medical Center
- Nevada
  - Carson City, Nevada, Forente stater, 89703
    - Carson Tahoe Regional Medical Center
  - Henderson, Nevada, Forente stater, 89052
    - Comprehensive Cancer Centers of Nevada - Henderson
  - Henderson, Nevada, Forente stater, 89052
    - Cancer and Blood Specialists-Henderson
  - Henderson, Nevada, Forente stater, 89052
    - Las Vegas Cancer Center-Henderson
  - Henderson, Nevada, Forente stater, 89074
    - Comprehensive Cancer Centers of Nevada-Southeast Henderson
  - Henderson, Nevada, Forente stater, 89074
    - 21st Century Oncology - Henderson
  - Henderson, Nevada, Forente stater, 89052
    - Nevada Cancer Specialists-Saint Rose
  - Las Vegas, Nevada, Forente stater, 89144
    - Summerlin Hospital Medical Center
  - Las Vegas, Nevada, Forente stater, 89106
    - Radiation Oncology Centers of Nevada Central
  - Las Vegas, Nevada, Forente stater, 89119
    - Radiation Oncology Centers of Nevada Southeast
  - Las Vegas, Nevada, Forente stater, 89128
    - Comprehensive Cancer Centers of Nevada - Northwest
  - Las Vegas, Nevada, Forente stater, 89144
    - Comprehensive Cancer Centers of Nevada-Summerlin
  - Las Vegas, Nevada, Forente stater, 89148
    - Comprehensive Cancer Centers of Nevada
  - Las Vegas, Nevada, Forente stater, 89169
    - Comprehensive Cancer Centers of Nevada - Central Valley
  - Las Vegas, Nevada, Forente stater, 89102
    - University Medical Center of Southern Nevada
  - Las Vegas, Nevada, Forente stater, 89106
    - Cancer and Blood Specialists-Shadow
  - Las Vegas, Nevada, Forente stater, 89109
    - HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
  - Las Vegas, Nevada, Forente stater, 89113
    - HealthCare Partners Medical Group Oncology/Hematology-San Martin
  - Las Vegas, Nevada, Forente stater, 89121
    - Cancer Therapy and Integrative Medicine
  - Las Vegas, Nevada, Forente stater, 89128
    - Cancer and Blood Specialists-Tenaya
  - Las Vegas, Nevada, Forente stater, 89128
    - HealthCare Partners Medical Group Oncology/Hematology-Tenaya
  - Las Vegas, Nevada, Forente stater, 89148-2405
    - Las Vegas Cancer Center-Medical Center
  - Las Vegas, Nevada, Forente stater, 89149
    - HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
  - Las Vegas, Nevada, Forente stater, 89109
    - 21st Century Oncology
  - Las Vegas, Nevada, Forente stater, 89148
    - 21st Century Oncology - Fort Apache
  - Las Vegas, Nevada, Forente stater, 89148
    - Nevada Cancer Specialists-Fort Apache
  - Las Vegas, Nevada, Forente stater, 89182
    - 21st Century Oncology - Vegas Tenaya
  - Las Vegas, Nevada, Forente stater, 89128
    - Ann M Wierman MD LTD
  - Las Vegas, Nevada, Forente stater, 89102
    - Desert West Surgery
  - Las Vegas, Nevada, Forente stater, 89169
    - University Cancer Center
  - Las Vegas, Nevada, Forente stater, 89128
    - Nevada Cancer Specialists-Tenaya
  - Las Vegas, Nevada, Forente stater, 89102
    - Nevada Cancer Specialists?Oakey
  - Reno, Nevada, Forente stater, 89502
    - Renown Regional Medical Center
  - Reno, Nevada, Forente stater, 89503
    - Saint Mary's Regional Medical Center
- New Hampshire
  - Concord, New Hampshire, Forente stater, 03301
    - New Hampshire Oncology Hematology PA-Concord
  - Hooksett, New Hampshire, Forente stater, 03106
    - New Hampshire Oncology Hematology PA-Hooksett
  - Lebanon, New Hampshire, Forente stater, 03756
    - Dartmouth Hitchcock Medical Center
  - Manchester, New Hampshire, Forente stater, 03102
    - Norris Cotton Cancer Center-Manchester
- New Jersey
  - Brick, New Jersey, Forente stater, 08724
    - Ocean Medical Center
  - Holmdel, New Jersey, Forente stater, 07733
    - Bayshore Community Hospital
  - Manahawkin, New Jersey, Forente stater, 08050
    - Southern Ocean County Medical Center
  - Neptune, New Jersey, Forente stater, 07753
    - Jersey Shore Medical Center
  - Newark, New Jersey, Forente stater, 07112
    - Newark Beth Israel Medical Center
  - Paramus, New Jersey, Forente stater, 07652
    - The Valley Hospital-Luckow Pavilion
  - Red Bank, New Jersey, Forente stater, 07701
    - Riverview Medical Center/Booker Cancer Center
  - Ridgewood, New Jersey, Forente stater, 07450
    - Valley Hospital
  - Ridgewood, New Jersey, Forente stater, 07450
    - Neurosurgeons of New Jersey-Ridgewood
  - Westwood, New Jersey, Forente stater, 07675
    - Valley Health System-Hematology/Oncology
- New Mexico
  - Albuquerque, New Mexico, Forente stater, 87102
    - University of New Mexico Cancer Center
  - Albuquerque, New Mexico, Forente stater, 87102
    - Lovelace Medical Center-Downtown
  - Albuquerque, New Mexico, Forente stater, 87109
    - New Mexico Oncology Hematology Consultants
  - Las Cruces, New Mexico, Forente stater, 88011
    - Memorial Medical Center - Las Cruces
- New York
  - Bronx, New York, Forente stater, 10461
    - Montefiore Medical Center-Einstein Campus
  - Bronx, New York, Forente stater, 10461
    - Montefiore Medical Center-Weiler Hospital
  - Bronx, New York, Forente stater, 10467-2490
    - Montefiore Medical Center - Moses Campus
  - Brooklyn, New York, Forente stater, 11203
    - State University of New York Downstate Medical Center
  - Buffalo, New York, Forente stater, 14263
    - Roswell Park Cancer Institute
  - Cooperstown, New York, Forente stater, 13326
    - Mary Imogene Bassett Hospital
  - Elmira, New York, Forente stater, 14905
    - Arnot Ogden Medical Center/Falck Cancer Center
  - Glens Falls, New York, Forente stater, 12801
    - Glens Falls Hospital
  - New York, New York, Forente stater, 10032
    - Columbia University/Herbert Irving Cancer Center
  - Syracuse, New York, Forente stater, 13210
    - State University of New York Upstate Medical University
  - Utica, New York, Forente stater, 13502
    - Faxton-Saint Luke's Healthcare
- North Carolina
  - Asheboro, North Carolina, Forente stater, 27203
    - Randolph Hospital
  - Asheville, North Carolina, Forente stater, 28801
    - Cancer Care of Western North Carolina
  - Asheville, North Carolina, Forente stater, 28801
    - Mission Hospital-Memorial Campus
  - Asheville, North Carolina, Forente stater, 28803
    - Asheville Hematology-Oncology Associates
  - Burlington, North Carolina, Forente stater, 27215
    - Cone Health Cancer Center at Alamance Regional
  - Charlotte, North Carolina, Forente stater, 28204
    - Novant Health Presbyterian Medical Center
  - Charlotte, North Carolina, Forente stater, 28207
    - Oncology Specialists of Charlotte
  - Charlotte, North Carolina, Forente stater, 28262
    - Southern Oncology Specialists-Charlotte
  - Clinton, North Carolina, Forente stater, 28328
    - Southeastern Medical Oncology Center-Clinton
  - Goldsboro, North Carolina, Forente stater, 27534
    - Southeastern Medical Oncology Center-Goldsboro
  - Goldsboro, North Carolina, Forente stater, 27534
    - Wayne Memorial Hospital
  - Greensboro, North Carolina, Forente stater, 27403
    - Cone Health Cancer Center
  - Hendersonville, North Carolina, Forente stater, 28791
    - Margaret R Pardee Memorial Hospital
  - Hendersonville, North Carolina, Forente stater, 28792
    - Park Ridge Hospital Breast Health Center
  - Huntersville, North Carolina, Forente stater, 28078
    - Southern Oncology Specialists-Huntersville
  - Huntersville, North Carolina, Forente stater, 28078
    - Lake Norman Hematology Oncology Specialists-Huntersville
  - Jacksonville, North Carolina, Forente stater, 28546
    - Southeastern Medical Oncology Center-Jacksonville
  - Jacksonville, North Carolina, Forente stater, 28546
    - Onslow Memorial Hospital
  - Matthews, North Carolina, Forente stater, 28105
    - Matthews Radiation Oncology Center
  - Mebane, North Carolina, Forente stater, 27302
    - Cone Heath Cancer Center at Mebane
  - Mooresville, North Carolina, Forente stater, 28117
    - Lake Norman Hematology Oncology Specialists-Mooresville
  - Pinehurst, North Carolina, Forente stater, 28374
    - FirstHealth of the Carolinas-Moore Regional Hosiptal
  - Reidsville, North Carolina, Forente stater, 27320
    - Annie Penn Memorial Hospital
  - Salisbury, North Carolina, Forente stater, 28144
    - Carolina Oncology Associates PA
  - Salisbury, North Carolina, Forente stater, 28144
    - Rowan Regional Medical Center
  - Wilson, North Carolina, Forente stater, 27893
    - Southeastern Medical Oncology Center-Wilson
- North Dakota
  - Bismarck, North Dakota, Forente stater, 58501
    - Sanford Bismarck Medical Center
  - Fargo, North Dakota, Forente stater, 58103
    - Essentia Health Cancer Center-South University Clinic
  - Fargo, North Dakota, Forente stater, 58122
    - Sanford Broadway Medical Center
  - Fargo, North Dakota, Forente stater, 58122
    - Roger Maris Cancer Center
  - Minot, North Dakota, Forente stater, 58701
    - Trinity Cancer Care Center
- Ohio
  - Beachwood, Ohio, Forente stater, 44122
    - UHHS-Chagrin Highlands Medical Center
  - Belpre, Ohio, Forente stater, 45714
    - Strecker Cancer Center-Belpre
  - Canton, Ohio, Forente stater, 44710
    - Aultman Health Foundation
  - Canton, Ohio, Forente stater, 44708
    - Mercy Medical Center
  - Centerville, Ohio, Forente stater, 45459
    - Miami Valley Hospital South
  - Centerville, Ohio, Forente stater, 45459
    - Dayton Physicians LLC-Miami Valley South
  - Chardon, Ohio, Forente stater, 44024
    - Geaugra Hospital
  - Chillicothe, Ohio, Forente stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forente stater, 45220
    - Good Samaritan Hospital - Cincinnati
  - Cincinnati, Ohio, Forente stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forente stater, 45236
    - Oncology Hematology Care Inc-Kenwood
  - Cincinnati, Ohio, Forente stater, 45219
    - University of Cincinnati/Barrett Cancer Center
  - Cincinnati, Ohio, Forente stater, 45247
    - TriHealth Cancer Institute-Westside
  - Cincinnati, Ohio, Forente stater, 45255
    - TriHealth Cancer Institute-Anderson
  - Cleveland, Ohio, Forente stater, 44106
    - Case Western Reserve University
  - Cleveland, Ohio, Forente stater, 44109
    - MetroHealth Medical Center
  - Cleveland, Ohio, Forente stater, 44195
    - Cleveland Clinic Foundation
  - Cleveland, Ohio, Forente stater, 44111
    - Cleveland Clinic Cancer Center/Fairview Hospital
  - Columbus, Ohio, Forente stater, 43214
    - Riverside Methodist Hospital
  - Columbus, Ohio, Forente stater, 43210
    - Ohio State University Comprehensive Cancer Center
  - Columbus, Ohio, Forente stater, 43219
    - The Mark H Zangmeister Center
  - Columbus, Ohio, Forente stater, 43214
    - Columbus Oncology and Hematology Associates Inc
  - Columbus, Ohio, Forente stater, 43228
    - Doctors Hospital
  - Columbus, Ohio, Forente stater, 43213
    - Mount Carmel East Hospital
  - Columbus, Ohio, Forente stater, 43215
    - Grant Medical Center
  - Columbus, Ohio, Forente stater, 43222
    - Mount Carmel Health Center West
  - Dayton, Ohio, Forente stater, 45406
    - Good Samaritan Hospital - Dayton
  - Dayton, Ohio, Forente stater, 45409
    - Miami Valley Hospital
  - Dayton, Ohio, Forente stater, 45415
    - Dayton Physicians LLC-Samaritan North
  - Dayton, Ohio, Forente stater, 45415
    - Samaritan North Health Center
  - Delaware, Ohio, Forente stater, 43015
    - Delaware Health Center-Grady Cancer Center
  - Delaware, Ohio, Forente stater, 43015
    - Delaware Radiation Oncology
  - Delaware, Ohio, Forente stater, 43015
    - Grady Memorial Hospital
  - Elyria, Ohio, Forente stater, 44035
    - Mercy Cancer Center-Elyria
  - Findlay, Ohio, Forente stater, 45840
    - Blanchard Valley Hospital
  - Findlay, Ohio, Forente stater, 45840
    - Armes Family Cancer Center
  - Findlay, Ohio, Forente stater, 45840
    - Orion Cancer Care
  - Franklin, Ohio, Forente stater, 45005-1066
    - Atrium Medical Center-Middletown Regional Hospital
  - Franklin, Ohio, Forente stater, 45005
    - Dayton Physicians LLC-Atrium
  - Greenville, Ohio, Forente stater, 45331
    - Wayne Hospital
  - Greenville, Ohio, Forente stater, 45331
    - Dayton Physicians LLC-Wayne
  - Independence, Ohio, Forente stater, 44131
    - Cleveland Clinic Cancer Center Independence
  - Kettering, Ohio, Forente stater, 45429
    - Kettering Medical Center
  - Kettering, Ohio, Forente stater, 45409
    - Greater Dayton Cancer Center
  - Kettering, Ohio, Forente stater, 45420
    - First Dayton Cancer Care
  - Lancaster, Ohio, Forente stater, 43130
    - Fairfield Medical Center
  - Mansfield, Ohio, Forente stater, 44906
    - Cleveland Clinic Cancer Center Mansfield
  - Mansfield, Ohio, Forente stater, 44903
    - OhioHealth Mansfield Hospital
  - Marietta, Ohio, Forente stater, 45750
    - Marietta Memorial Hospital
  - Marion, Ohio, Forente stater, 43302
    - OneHealth Marion General Hospital
  - Mayfield Heights, Ohio, Forente stater, 44124
    - Hillcrest Hospital Cancer Center
  - Mayfield Heights, Ohio, Forente stater, 44124
    - Ireland Cancer Center Landerbrook Health Center
  - Mentor, Ohio, Forente stater, 44060
    - Lake University Ireland Cancer Center
  - Middleburg Heights, Ohio, Forente stater, 44130
    - Southwest General Health Center Ireland Cancer Center
  - Mount Vernon, Ohio, Forente stater, 43050
    - Knox Community Hospital
  - Newark, Ohio, Forente stater, 43055
    - Licking Memorial Hospital
  - Newark, Ohio, Forente stater, 43055
    - Newark Radiation Oncology
  - Portsmouth, Ohio, Forente stater, 45662
    - Southern Ohio Medical Center
  - Sandusky, Ohio, Forente stater, 44870
    - North Coast Cancer Care
  - Sandusky, Ohio, Forente stater, 44870
    - Ireland Cancer Center at Firelands Regional Medical Center
  - Springfield, Ohio, Forente stater, 45505
    - Springfield Regional Medical Center
  - Springfield, Ohio, Forente stater, 45504
    - Springfield Regional Cancer Center
  - Strongsville, Ohio, Forente stater, 44136
    - Cleveland Clinic Cancer Center Strongsville
  - Sylvania, Ohio, Forente stater, 43560
    - Flower Hospital
  - Toledo, Ohio, Forente stater, 43614
    - University of Toledo
  - Toledo, Ohio, Forente stater, 43606
    - The Toledo Hospital/Toledo Children's Hospital
  - Troy, Ohio, Forente stater, 45373
    - Upper Valley Medical Center
  - Troy, Ohio, Forente stater, 45373
    - Dayton Physicians LLC-Upper Valley
  - Wadsworth, Ohio, Forente stater, 44281
    - University Hospitals Sharon Health Center
  - West Chester, Ohio, Forente stater, 45069
    - University Pointe
  - Westerville, Ohio, Forente stater, 43081
    - Saint Ann's Hospital
  - Westlake, Ohio, Forente stater, 44145
    - UHHS-Westlake Medical Center
  - Westlake, Ohio, Forente stater, 44145
    - UH-Seidman Cancer Center at Saint John Medical Center
  - Wooster, Ohio, Forente stater, 44691
    - Cleveland Clinic Wooster Family Health and Surgery Center
  - Zanesville, Ohio, Forente stater, 43701
    - Genesis Healthcare System Cancer Care Center
- Oklahoma
  - Lawton, Oklahoma, Forente stater, 73505
    - Cancer Centers of Southwest Oklahoma Research
  - Oklahoma City, Oklahoma, Forente stater, 73104
    - University of Oklahoma Health Sciences Center
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Mercy Hospital Oklahoma City
  - Tulsa, Oklahoma, Forente stater, 74146
    - Oklahoma Cancer Specialists and Research Institute-Tulsa
- Oregon
  - Baker City, Oregon, Forente stater, 97814
    - Saint Alphonsus Medical Center-Baker City
  - Bend, Oregon, Forente stater, 97701
    - Saint Charles Health System
  - Clackamas, Oregon, Forente stater, 97015
    - Clackamas Radiation Oncology Center
  - Clackamas, Oregon, Forente stater, 97015
    - Providence Oncology and Hematology Care Southeast
  - Coos Bay, Oregon, Forente stater, 97420
    - Bay Area Hospital
  - Gresham, Oregon, Forente stater, 97030
    - Legacy Mount Hood Medical Center
  - Newberg, Oregon, Forente stater, 97132
    - Providence Newberg Medical Center
  - Ontario, Oregon, Forente stater, 97914
    - Saint Alphonsus Medical Center-Ontario
  - Portland, Oregon, Forente stater, 97239
    - Oregon Health and Science University
  - Portland, Oregon, Forente stater, 97210
    - Legacy Good Samaritan Hospital and Medical Center
  - Portland, Oregon, Forente stater, 97213
    - Providence Portland Medical Center
  - Portland, Oregon, Forente stater, 97225
    - Providence Saint Vincent Medical Center
  - Portland, Oregon, Forente stater, 97227
    - Kaiser Permanente Northwest
  - Portland, Oregon, Forente stater, 97239
    - SWOG
- Pennsylvania
  - Allentown, Pennsylvania, Forente stater, 18103
    - Lehigh Valley Hospital-Cedar Crest
  - Beaver, Pennsylvania, Forente stater, 15009
    - UPMC-Heritage Valley Health System Beaver
  - Bethlehem, Pennsylvania, Forente stater, 18017
    - Lehigh Valley Hospital - Muhlenberg
  - Bryn Mawr, Pennsylvania, Forente stater, 19010
    - Bryn Mawr Hospital
  - Chadds Ford, Pennsylvania, Forente stater, 19317
    - Christiana Care Health System-Concord Health Center
  - Danville, Pennsylvania, Forente stater, 17822
    - Geisinger Medical Center
  - Ephrata, Pennsylvania, Forente stater, 17522
    - Ephrata Cancer Center
  - Ephrata, Pennsylvania, Forente stater, 17522
    - Ephrata Community Hospital
  - Gettysburg, Pennsylvania, Forente stater, 17325
    - Adams Cancer Center
  - Greensburg, Pennsylvania, Forente stater, 15601
    - UPMC Cancer Centers - Arnold Palmer Pavilion
  - Hanover, Pennsylvania, Forente stater, 17331
    - Cherry Tree Cancer Center
  - Hazleton, Pennsylvania, Forente stater, 18201
    - Geisinger Medical Center-Cancer Center Hazleton
  - Hershey, Pennsylvania, Forente stater, 17033-0850
    - Penn State Milton S Hershey Medical Center
  - Jefferson Hills, Pennsylvania, Forente stater, 15025
    - Jefferson Hospital
  - Johnstown, Pennsylvania, Forente stater, 15901
    - UPMC-Johnstown/John P. Murtha Regional Cancer Center
  - Kittanning, Pennsylvania, Forente stater, 16201
    - Armstrong Center for Medicine and Health
  - Lebanon, Pennsylvania, Forente stater, 17042
    - Sechler Family Cancer Center
  - Lewisburg, Pennsylvania, Forente stater, 17837
    - Geisinger Medical Oncology-Lewisburg
  - Lewistown, Pennsylvania, Forente stater, 17044
    - Lewistown Hospital
  - McKeesport, Pennsylvania, Forente stater, 15132
    - UPMC Cancer Center at UPMC McKeesport
  - Media, Pennsylvania, Forente stater, 19063
    - Riddle Memorial Hospital
  - Monroeville, Pennsylvania, Forente stater, 15146
    - Forbes Hospital
  - Moon, Pennsylvania, Forente stater, 15108
    - UPMC-Coraopolis/Heritage Valley Radiation Oncology
  - Natrona Heights, Pennsylvania, Forente stater, 15065
    - Allegheny Valley Hospital
  - Paoli, Pennsylvania, Forente stater, 19301
    - Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19111
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forente stater, 19104
    - University of Pennsylvania/Abramson Cancer Center
  - Philadelphia, Pennsylvania, Forente stater, 19140
    - Temple University Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15212
    - Allegheny General Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15224
    - West Penn Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15213
    - UPMC-Magee Womens Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15232
    - University of Pittsburgh Cancer Institute (UPCI)
  - Pittsburgh, Pennsylvania, Forente stater, 15232
    - UPMC-Shadyside Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15213
    - UPMC-Presbyterian Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15215
    - UPMC-Saint Margaret
  - Pittsburgh, Pennsylvania, Forente stater, 15237
    - UPMC-Passavant Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15243
    - UPMC-Saint Clair Hospital Cancer Center
  - Pottstown, Pennsylvania, Forente stater, 19464
    - Pottstown Memorial Medical Center
  - Pottsville, Pennsylvania, Forente stater, 17901
    - Geisinger Medical Oncology-Pottsville
  - Reading, Pennsylvania, Forente stater, 19605
    - Penn State Health Saint Joseph Medical Center
  - Sayre, Pennsylvania, Forente stater, 18840
    - Guthrie Medical Group PC-Robert Packer Hospital
  - Scranton, Pennsylvania, Forente stater, 18510
    - Community Medical Center
  - Selinsgrove, Pennsylvania, Forente stater, 17870
    - Geisinger Medical Oncology-Selinsgrove
  - Seneca, Pennsylvania, Forente stater, 16346
    - UPMC Cancer Center at UPMC Northwest
  - State College, Pennsylvania, Forente stater, 16801
    - Geisinger Medical Group
  - Uniontown, Pennsylvania, Forente stater, 15401
    - UPMC Uniontown Hospital Radiation Oncology
  - Washington, Pennsylvania, Forente stater, 15301
    - UPMC Washington Hospital Radiation Oncology
  - Wexford, Pennsylvania, Forente stater, 15090
    - Wexford Health and Wellness Pavilion
  - Wilkes-Barre, Pennsylvania, Forente stater, 18711
    - Geisinger Wyoming Valley/Henry Cancer Center
  - Williamsport, Pennsylvania, Forente stater, 17701
    - UPMC Susquehanna
  - Wynnewood, Pennsylvania, Forente stater, 19096
    - Lankenau Medical Center
  - York, Pennsylvania, Forente stater, 17403
    - WellSpan Health-York Cancer Center
  - York, Pennsylvania, Forente stater, 17403
    - WellSpan Health-York Hospital
- South Carolina
  - Anderson, South Carolina, Forente stater, 29621
    - AnMed Health Cancer Center
  - Charleston, South Carolina, Forente stater, 29401
    - Roper Hospital
  - Charleston, South Carolina, Forente stater, 29403
    - Charleston Hematology Oncology Associates-Roper
  - Charleston, South Carolina, Forente stater, 29406
    - Lowcountry Hematology Oncology PA-North Charleston
  - Charleston, South Carolina, Forente stater, 29414
    - Bon Secours Saint Francis Hospital
  - Charleston, South Carolina, Forente stater, 29414
    - Charleston Hematology Oncology Associates PA-St. Francis
  - Charleston, South Carolina, Forente stater, 29414
    - Lowcountry Hematology Oncology PA-West Ashley
  - Easley, South Carolina, Forente stater, 29640
    - Greenville Health System Cancer Institute-Easley
  - Gaffney, South Carolina, Forente stater, 29341
    - Gibbs Cancer Center-Gaffney
  - Georgetown, South Carolina, Forente stater, 29440
    - Georgetown Hospital System
  - Greenville, South Carolina, Forente stater, 29607
    - Saint Francis Cancer Center
  - Greenville, South Carolina, Forente stater, 29601
    - Saint Francis Hospital
  - Greenville, South Carolina, Forente stater, 29605
    - Greenville Health System Cancer Institute-Faris
  - Greenville, South Carolina, Forente stater, 29605
    - Greenville Memorial Hospital
  - Greenville, South Carolina, Forente stater, 29615
    - Greenville Health System Cancer Institute-Eastside
  - Greenville, South Carolina, Forente stater, 29605
    - Greenville Health System Cancer Institute-Butternut
  - Greer, South Carolina, Forente stater, 29651
    - Gibbs Cancer Center-Pelham
  - Mount Pleasant, South Carolina, Forente stater, 29464
    - Lowcountry Hematology Oncology PA-Mount Pleasant
  - Seneca, South Carolina, Forente stater, 29672
    - Greenville Health System Cancer Institute-Seneca
  - Spartanburg, South Carolina, Forente stater, 29303
    - Spartanburg Medical Center
  - Spartanburg, South Carolina, Forente stater, 29307
    - Greenville Health System Cancer Institute-Spartanburg
  - Union, South Carolina, Forente stater, 29379
    - MGC Hematology Oncology-Union
  - West Columbia, South Carolina, Forente stater, 29169
    - Lexington Medical Center
- South Dakota
  - Aberdeen, South Dakota, Forente stater, 57401
    - Avera Cancer Institute-Aberdeen
  - Rapid City, South Dakota, Forente stater, 57701
    - Rapid City Regional Hospital
  - Sioux Falls, South Dakota, Forente stater, 57105
    - Avera Cancer Institute
  - Sioux Falls, South Dakota, Forente stater, 57117-5134
    - Sanford USD Medical Center - Sioux Falls
  - Sioux Falls, South Dakota, Forente stater, 57104
    - Sanford Cancer Center-Oncology Clinic
- Tennessee
  - Chattanooga, Tennessee, Forente stater, 37404
    - Memorial Hospital
  - Cookeville, Tennessee, Forente stater, 38501
    - Cookeville Regional Medical Center
  - Franklin, Tennessee, Forente stater, 37067
    - Vanderbilt-Ingram Cancer Center Cool Springs
  - Hixson, Tennessee, Forente stater, 37343
    - Pulmonary Medicine Center of Chattanooga-Hixson
  - Memphis, Tennessee, Forente stater, 38120
    - Baptist Memorial Hospital and Cancer Center-Memphis
  - Memphis, Tennessee, Forente stater, 38120
    - Baptist Memorial Hospital for Women
  - Nashville, Tennessee, Forente stater, 37232
    - Vanderbilt University/Ingram Cancer Center
  - Nashville, Tennessee, Forente stater, 37204
    - Vanderbilt Breast Center at One Hundred Oaks
  - Nashville, Tennessee, Forente stater, 37208
    - Meharry Medical College
  - Ooltewah, Tennessee, Forente stater, 37363
    - Memorial GYN Plus
- Texas
  - Amarillo, Texas, Forente stater, 79106
    - The Don and Sybil Harrington Cancer Center
  - Bryan, Texas, Forente stater, 77802
    - Saint Joseph Regional Cancer Center
  - Dallas, Texas, Forente stater, 75235
    - Parkland Memorial Hospital
  - Dallas, Texas, Forente stater, 75390
    - UT Southwestern/Simmons Cancer Center-Dallas
  - Houston, Texas, Forente stater, 77030
    - M D Anderson Cancer Center
  - Houston, Texas, Forente stater, 77030
    - Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
  - Houston, Texas, Forente stater, 77030
    - The Methodist Hospital System
  - Houston, Texas, Forente stater, 77030
    - Ben Taub General Hospital
  - Lubbock, Texas, Forente stater, 79410
    - Covenant Medical Center-Lakeside
  - San Antonio, Texas, Forente stater, 78229
    - University of Texas Health Science Center at San Antonio
- Utah
  - American Fork, Utah, Forente stater, 84003
    - American Fork Hospital / Huntsman Intermountain Cancer Center
  - Cedar City, Utah, Forente stater, 84720
    - Sandra L Maxwell Cancer Center
  - Logan, Utah, Forente stater, 84321
    - Logan Regional Hospital
  - Murray, Utah, Forente stater, 84107
    - Intermountain Medical Center
  - Ogden, Utah, Forente stater, 84403
    - McKay-Dee Hospital Center
  - Provo, Utah, Forente stater, 84604
    - Utah Valley Regional Medical Center
  - Riverton, Utah, Forente stater, 84065
    - Riverton Hospital
  - Saint George, Utah, Forente stater, 84770
    - Dixie Medical Center Regional Cancer Center
  - Salt Lake City, Utah, Forente stater, 84106
    - Utah Cancer Specialists-Salt Lake City
  - Salt Lake City, Utah, Forente stater, 84143
    - LDS Hospital
- Vermont
  - Berlin, Vermont, Forente stater, 05602
    - Central Vermont Medical Center/National Life Cancer Treatment
  - Burlington, Vermont, Forente stater, 05401
    - University of Vermont Medical Center
  - Burlington, Vermont, Forente stater, 05405
    - University of Vermont College of Medicine
- Virginia
  - Burke, Virginia, Forente stater, 22015
    - Kaiser Permanente-Burke Medical Center
  - Charlottesville, Virginia, Forente stater, 22908
    - University of Virginia Cancer Center
  - Fredericksburg, Virginia, Forente stater, 22408
    - Hematology Oncology Associates of Fredericksburg Inc
  - Lynchburg, Virginia, Forente stater, 24501
    - Lynchburg Hematology-Oncology Clinic
  - Martinsville, Virginia, Forente stater, 24115
    - Memorial Hospital Of Martinsville
  - McLean, Virginia, Forente stater, 22102
    - Kaiser Permanente Tysons Corner Medical Center
  - Mechanicsville, Virginia, Forente stater, 23116
    - Bon Secours Memorial Regional Medical Center
  - Midlothian, Virginia, Forente stater, 23114
    - Bon Secours Saint Francis Medical Center
  - Norfolk, Virginia, Forente stater, 23505
    - DePaul Medical Center
  - Richmond, Virginia, Forente stater, 23298
    - Virginia Commonwealth University/Massey Cancer Center
  - Richmond, Virginia, Forente stater, 23230
    - Virginia Cancer Institute
  - Richmond, Virginia, Forente stater, 23226
    - Bon Secours Saint Mary's Hospital
  - South Hill, Virginia, Forente stater, 23970
    - VCU Community Memorial Health Center
  - Winchester, Virginia, Forente stater, 22601
    - Shenandoah Oncology Associates PC
- Washington
  - Aberdeen, Washington, Forente stater, 98520
    - Providence Regional Cancer System-Aberdeen
  - Auburn, Washington, Forente stater, 98001
    - MultiCare Auburn Medical Center
  - Bainbridge Island, Washington, Forente stater, 98110
    - Virginia Mason Bainbridge Island Medical Center
  - Bellevue, Washington, Forente stater, 98004
    - Overlake Hospital Medical Center
  - Bellingham, Washington, Forente stater, 98225
    - PeaceHealth Saint Joseph Medical Center
  - Bremerton, Washington, Forente stater, 98310
    - Harrison HealthPartners Hematology and Oncology-Bremerton
  - Bremerton, Washington, Forente stater, 98310
    - Harrison Medical Center
  - Burien, Washington, Forente stater, 98166
    - Highline Medical Center-Main Campus
  - Centralia, Washington, Forente stater, 98531
    - Providence Regional Cancer System-Centralia
  - Edmonds, Washington, Forente stater, 98026
    - Swedish Medical Center-Edmonds
  - Enumclaw, Washington, Forente stater, 98022
    - Saint Elizabeth Hospital
  - Everett, Washington, Forente stater, 98201
    - Providence Regional Cancer Partnership
  - Federal Way, Washington, Forente stater, 98002
    - Virginia Mason Federal Way Medical Center
  - Federal Way, Washington, Forente stater, 98003
    - Saint Francis Hospital
  - Gig Harbor, Washington, Forente stater, 98332
    - Tacoma/Valley Radiation Oncology Centers-Gig Harbor
  - Gig Harbor, Washington, Forente stater, 98335
    - MultiCare Gig Harbor Medical Park
  - Issaquah, Washington, Forente stater, 98029
    - Swedish Cancer Institute-Issaquah
  - Kennewick, Washington, Forente stater, 99336
    - Kadlec Clinic Hematology and Oncology
  - Kennewick, Washington, Forente stater, 99336
    - Northwest Cancer Clinic
  - Kirkland, Washington, Forente stater, 98034
    - Seattle Cancer Care Alliance at EvergreenHealth
  - Lacey, Washington, Forente stater, 98503
    - Providence Regional Cancer System-Lacey
  - Lakewood, Washington, Forente stater, 98499
    - Saint Clare Hospital
  - Longview, Washington, Forente stater, 98632
    - PeaceHealth Saint John Medical Center
  - Lynnwood, Washington, Forente stater, 98036
    - Virginia Mason Lynnwood Medical Center
  - Mount Vernon, Washington, Forente stater, 98273
    - Skagit Valley Hospital Regional Cancer Care Center
  - Mount Vernon, Washington, Forente stater, 98274
    - Skagit Valley Hospital
  - Port Townsend, Washington, Forente stater, 98368
    - Jefferson Healthcare
  - Poulsbo, Washington, Forente stater, 98370
    - Harrison HealthPartners Hematology and Oncology-Poulsbo
  - Poulsbo, Washington, Forente stater, 98370
    - Peninsula Cancer Center
  - Puyallup, Washington, Forente stater, 98372
    - MultiCare Good Samaritan Hospital
  - Puyallup, Washington, Forente stater, 98372
    - Tacoma/Valley Radiation Oncology Centers-Puyallup
  - Renton, Washington, Forente stater, 98055
    - Valley Medical Center
  - Seattle, Washington, Forente stater, 98109
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forente stater, 98109
    - Seattle Cancer Care Alliance
  - Seattle, Washington, Forente stater, 98195
    - University of Washington Medical Center
  - Seattle, Washington, Forente stater, 98101
    - Virginia Mason Medical Center
  - Seattle, Washington, Forente stater, 98107
    - Swedish Medical Center-Ballard Campus
  - Seattle, Washington, Forente stater, 98112
    - Kaiser Permanente Washington
  - Seattle, Washington, Forente stater, 98104
    - Pacific Gynecology Specialists
  - Seattle, Washington, Forente stater, 98122-4307
    - Swedish Medical Center-First Hill
  - Seattle, Washington, Forente stater, 98133
    - Seattle Cancer Care Alliance at Northwest Hospital
  - Seattle, Washington, Forente stater, 98122-5711
    - Swedish Medical Center-Cherry Hill
  - Shelton, Washington, Forente stater, 98584
    - Providence Regional Cancer System-Shelton
  - Spokane, Washington, Forente stater, 99204
    - Rockwood Cancer Treatment Center-DHEC-Downtown
  - Spokane, Washington, Forente stater, 99202
    - Cancer Care Northwest - Spokane South
  - Spokane, Washington, Forente stater, 99208
    - Spokane Valley Cancer Center-Mayfair
  - Spokane, Washington, Forente stater, 99216
    - Cancer Care Northwest-Valley
  - Spokane, Washington, Forente stater, 99218
    - Cancer Care Northwest-North Spokane
  - Spokane, Washington, Forente stater, 99216
    - Spokane Valley Cancer Center-Mission
  - Spokane, Washington, Forente stater, 99218
    - Rockwood North Cancer Treatment Center
  - Spokane Valley, Washington, Forente stater, 99216
    - Rockwood Clinic Cancer Treatment Center-Valley
  - Tacoma, Washington, Forente stater, 98405
    - Northwest Medical Specialties PLLC
  - Tacoma, Washington, Forente stater, 98405
    - MultiCare Tacoma General Hospital
  - Tacoma, Washington, Forente stater, 98405
    - Tacoma/Valley Radiation Oncology Centers-Saint Joe's
  - Tacoma, Washington, Forente stater, 97405
    - Tacoma/Valley Radiation Oncology Centers-Jackson Hall
  - Tacoma, Washington, Forente stater, 98405
    - Franciscan Research Center-Northwest Medical Plaza
  - Vancouver, Washington, Forente stater, 98686
    - Legacy Salmon Creek Hospital
  - Vancouver, Washington, Forente stater, 98664
    - PeaceHealth Southwest Medical Center
  - Walla Walla, Washington, Forente stater, 99362
    - Providence Saint Mary Regional Cancer Center
  - Wenatchee, Washington, Forente stater, 98801
    - Wenatchee Valley Hospital and Clinics
  - Yakima, Washington, Forente stater, 98902
    - North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
  - Yelm, Washington, Forente stater, 98597
    - Providence Regional Cancer System-Yelm
- West Virginia
  - Bridgeport, West Virginia, Forente stater, 26330
    - United Hospital Center
  - Charleston, West Virginia, Forente stater, 25304
    - West Virginia University Charleston
  - Huntington, West Virginia, Forente stater, 25702
    - Saint Mary's Medical Center
  - Martinsburg, West Virginia, Forente stater, 25401
    - WVUH-East City Hospital
  - Morgantown, West Virginia, Forente stater, 26506
    - West Virginia University Healthcare
  - Parkersburg, West Virginia, Forente stater, 26101
    - Camden-Clark Memorial Hospital
- Wisconsin
  - Antigo, Wisconsin, Forente stater, 54409
    - Langlade Hospital and Cancer Center
  - Burlington, Wisconsin, Forente stater, 53105
    - Aurora Cancer Care-Southern Lakes VLCC
  - Chippewa Falls, Wisconsin, Forente stater, 54729
    - Marshfield Clinic-Chippewa Center
  - Eau Claire, Wisconsin, Forente stater, 54701
    - Marshfield Clinic Cancer Center at Sacred Heart
  - Eau Claire, Wisconsin, Forente stater, 54701
    - Sacred Heart Hospital
  - Eau Claire, Wisconsin, Forente stater, 54701
    - Marshfield Clinic Cancer Center - Eau Claire
  - Fond Du Lac, Wisconsin, Forente stater, 54937
    - Aurora Health Center-Fond du Lac
  - Germantown, Wisconsin, Forente stater, 53022
    - Aurora Health Care Germantown Health Center
  - Grafton, Wisconsin, Forente stater, 53024
    - Aurora Cancer Care-Grafton
  - Green Bay, Wisconsin, Forente stater, 54311
    - Aurora BayCare Medical Center
  - Green Bay, Wisconsin, Forente stater, 54301
    - Saint Vincent Hospital Cancer Center Green Bay
  - Green Bay, Wisconsin, Forente stater, 54303
    - Saint Vincent Hospital Cancer Center at Saint Mary's
  - Janesville, Wisconsin, Forente stater, 53547
    - Mercy Health System
  - Johnson Creek, Wisconsin, Forente stater, 53038
    - UW Cancer Center Johnson Creek
  - Kenosha, Wisconsin, Forente stater, 53142
    - Aurora Cancer Care-Kenosha South
  - La Crosse, Wisconsin, Forente stater, 54601
    - Gundersen Lutheran Medical Center
  - Ladysmith, Wisconsin, Forente stater, 54848
    - Marshfield Clinic - Ladysmith Center
  - Madison, Wisconsin, Forente stater, 53792
    - University of Wisconsin Hospital and Clinics
  - Manitowoc, Wisconsin, Forente stater, 54221
    - Holy Family Memorial Hospital
  - Marinette, Wisconsin, Forente stater, 54143
    - Aurora Bay Area Medical Group-Marinette
  - Marinette, Wisconsin, Forente stater, 54143
    - Vince Lombardi Cancer Clinic-Marinette
  - Marshfield, Wisconsin, Forente stater, 54449
    - Marshfield Clinic
  - Marshfield, Wisconsin, Forente stater, 54449
    - Saint Joseph's Hospital
  - Menomonee Falls, Wisconsin, Forente stater, 53051
    - Community Memorial Hospital
  - Milwaukee, Wisconsin, Forente stater, 53226
    - Froedtert and The Medical College of Wisconsin
  - Milwaukee, Wisconsin, Forente stater, 53209
    - Aurora Cancer Care-Milwaukee
  - Milwaukee, Wisconsin, Forente stater, 53215
    - Aurora Saint Luke's Medical Center
  - Milwaukee, Wisconsin, Forente stater, 53233
    - Aurora Sinai Medical Center
  - Minocqua, Wisconsin, Forente stater, 54548
    - Marshfield Clinic-Minocqua Center
  - New Richmond, Wisconsin, Forente stater, 54017
    - Cancer Center of Western Wisconsin
  - Oconto Falls, Wisconsin, Forente stater, 54154
    - Green Bay Oncology - Oconto Falls
  - Oshkosh, Wisconsin, Forente stater, 54904
    - Vince Lombardi Cancer Clinic - Oshkosh
  - Racine, Wisconsin, Forente stater, 53406
    - Aurora Cancer Care-Racine
  - Rice Lake, Wisconsin, Forente stater, 54868
    - Lakeview Medical Center-Marshfield Clinic
  - Rice Lake, Wisconsin, Forente stater, 54868
    - Marshfield Clinic-Rice Lake Center
  - Sheboygan, Wisconsin, Forente stater, 53081
    - Vince Lombardi Cancer Clinic-Sheboygan
  - Sheboygan, Wisconsin, Forente stater, 53081
    - HSHS Saint Nicholas Hospital
  - Stevens Point, Wisconsin, Forente stater, 54482
    - Marshfield Clinic Stevens Point Center
  - Sturgeon Bay, Wisconsin, Forente stater, 54235-1495
    - Saint Vincent Hospital Cancer Center at Sturgeon Bay
  - Summit, Wisconsin, Forente stater, 53066
    - Aurora Medical Center in Summit
  - Two Rivers, Wisconsin, Forente stater, 54241
    - Vince Lombardi Cancer Clinic-Two Rivers
  - Wausau, Wisconsin, Forente stater, 54401
    - Aspirus Regional Cancer Center
  - Wausau, Wisconsin, Forente stater, 54401
    - Marshfield Clinic-Wausau Center
  - Wauwatosa, Wisconsin, Forente stater, 53226
    - Aurora Cancer Care-Milwaukee West
  - West Allis, Wisconsin, Forente stater, 53227
    - Aurora West Allis Medical Center
  - West Bend, Wisconsin, Forente stater, 53095
    - The Alyce and Elmore Kraemer Cancer Care Center
  - Weston, Wisconsin, Forente stater, 54476
    - Diagnostic and Treatment Center
  - Weston, Wisconsin, Forente stater, 54476
    - Marshfield Clinic - Weston Center
  - Weston, Wisconsin, Forente stater, 54476
    - Saint Clare's Hospital
  - Wisconsin Rapids, Wisconsin, Forente stater, 54494
    - Marshfield Clinic - Wisconsin Rapids Center
  - Wisconsin Rapids, Wisconsin, Forente stater, 54494
    - Aspirus UW Cancer Center
- Wyoming
  - Cheyenne, Wyoming, Forente stater, 82001
    - Cheyenne Regional Medical Center-West
  - Cody, Wyoming, Forente stater, 82414
    - Billings Clinic-Cody
  - Sheridan, Wyoming, Forente stater, 82801
    - Welch Cancer Center

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Barn
Voksen
Eldre voksen

Tar imot friske frivillige

Nei

Beskrivelse

Inklusjonskriterier:

Pasienter må ha blitt tildelt S1400F
Pasienter må ha utviklet seg under eller etter tidligere platinabasert kjemoterapi; pasienter hvis eneste tidligere platinabaserte kjemoterapiregime var for stadium I-III sykdom (dvs. pasienten ikke har mottatt platinabasert kjemoterapi for stadium IV eller tilbakevendende sykdom), sykdomsprogresjon på platinabasert kjemoterapi må ha skjedd innen ett år fra siste dato da pasienten mottok den behandlingen; Pasienter må ha opplevd sykdomsprogresjon under eller etter tidligere monoterapi med anti-PD-1 eller anti-PD-L1 antistoff som sin siste behandlingslinje; tidligere PD-1/PD-L1 kombinasjonsbehandling er ikke tillatt
Tidligere eksponering for CTLA-4-hemmere (ipilimumab og tremelimumab) er ikke tillatt; tidligere eksponering for følgende er tillatt: svekkede vaksiner, anti-EGFR-midler og granulocytt-makrofag kolonistimulerende faktor (GM-CSF)
Pasienter må ikke ha mottatt nitrosourea eller mitomycin-C innen 42 dager før registrering av delstudie
Pasienter må ikke ha noen tidligere dokumentert autoimmun eller inflammatorisk sykdom (inkludert inflammatorisk tarmsykdom, divertikulitt med unntak av divertikulose, cøliaki, irritabel tarmsykdom; Wegners syndrom; Hashimoto syndrom) innen 3 år før registrering av delstudie; Pasienter med vitiligo, immunmediert alopecia, Graves sykdom eller psoriasis som krever systemisk behandling innen de siste 2 årene er ikke kvalifisert; pasienter med hypotyreose (f. post Hashimoto syndrom) som er stabile på hormonbehandling er kvalifisert
Pasienter må ikke ha noen historie med primær immunsvikt
Pasienter må ikke ha mottatt noen immunsuppressiv medisin innen 28 dager før delstudieregistrering og må ikke planlegge å motta disse medisinene mens de er på protokollbehandling; systemiske kortikosteroider må stoppes minst 24 timer før registrering av delstudie; intranasale og inhalerte kortikosteroider er imidlertid tillatt når som helst før og under protokollbehandling
Pasienter må ikke ha opplevd en grad 3 eller verre immunrelatert bivirkning (irAE) (unntatt asymptomatisk ikke-bulløst/ikke-eksfoliativt utslett) eller noe uløst irAE grad 2, og heller ikke ha opplevd en toksisitet som førte til permanent seponering av tidligere anti-PD-1 /PD-L1 immunterapi
Pasienter må ikke ha noen historie med organtransplantasjon som krever bruk av immundempende midler
Pasienter må ikke ha noen kjent allergi eller reaksjon på noen komponent i durvalumab (MEDI4736) og/eller tremelimumab-formuleringen
Pasienter må ikke ha kliniske tegn eller symptomer på aktiv tuberkuloseinfeksjon
Pasienter skal ikke ha mottatt en levende svekket vaksinasjon innen 28 dager før delstudieregistrering
Pasienter må ikke ha kjent humant immunsviktvirus (HIV), eller en kjent positiv test for hepatitt B virus overflateantigen (HBV sAg), eller hepatitt C virus ribonukleinsyre (HCV antistoff) som indikerer aktuell akutt eller kronisk infeksjon; Pasienter med positivt hepatitt C-antistoff med negativ virusmengde tillates
Pasienter må ha et thyreoideastimulerende hormon (TSH) med refleksfri T3/fri T4 (hvis TSH er utenfor normalområdet) og elektrokardiogram (EKG) innhentet innen 7 dager før delstudieregistrering
Pasienter skal også tilbys deltakelse i bankvirksomhet og i korrelasjonsstudiene for innsamling og fremtidig bruk av prøver.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Primært formål: Behandling
Tildeling: N/A
Intervensjonsmodell: Enkeltgruppeoppdrag
Masking: Ingen (Open Label)

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm	Intervensjon / Behandling
Eksperimentell: Behandling (tremelimumab, durvalumab) Pasienter får tremelimumab IV over 60 minutter på dag 1 for kurs 1-4 og durvalumab IV over 60 minutter på dag 1. Kurs gjentas hver 28. dag i fravær av sykdomsprogresjon eller uakseptabel toksisitet.	Annen: Laboratoriebiomarkøranalyse Korrelative studier Biologisk: Durvalumab Gitt IV Andre navn: Imfinzi Immunoglobulin G1, Anti-(Humant Protein B7-H1) (Human Monoklonal MEDI4736 Heavy Chain), Disulfid med Human Monoklonal MEDI4736 Kappa-kjede, Dimer MEDI-4736 MEDI4736 Biologisk: Tremelimumab Gitt IV Andre navn: Anti-CTLA4 humant monoklonalt antistoff CP-675,206 CP-675 CP-675.206 CP-675206 ticilimumab

Deltakergruppe / Arm

Intervensjon / Behandling

Eksperimentell: Behandling (tremelimumab, durvalumab)

Pasienter får tremelimumab IV over 60 minutter på dag 1 for kurs 1-4 og durvalumab IV over 60 minutter på dag 1. Kurs gjentas hver 28. dag i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

Annen: Laboratoriebiomarkøranalyse

Korrelative studier

Biologisk: Durvalumab

Gitt IV

Andre navn:

Imfinzi
Immunoglobulin G1, Anti-(Humant Protein B7-H1) (Human Monoklonal MEDI4736 Heavy Chain), Disulfid med Human Monoklonal MEDI4736 Kappa-kjede, Dimer
MEDI-4736
MEDI4736

Biologisk: Tremelimumab

Gitt IV

Andre navn:

Anti-CTLA4 humant monoklonalt antistoff CP-675,206
CP-675
CP-675.206
CP-675206
ticilimumab

Hva måler studien?

Primære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Objektiv responsrate Tidsramme: Fra registreringsdato til progresjon eller behandlingsavbrudd, inntil 2 år og 5,5 måneder.	Andel deltakere med bekreftet eller ubekreftet, fullstendig eller delvis respons på behandling med MEDI4736 (durvalumab) pluss tremelimumab per responsevalueringskriterier i solide tumorer (RECIST 1.1). Fullstendig respons (CR): Fullstendig forsvinning av alle mål- og ikke-mållesjoner. Ingen nye lesjoner. Ingen sykdomsrelaterte symptomer. Eventuelle lymfeknuter (enten mål eller ikke-mål) må ha reduksjon i kort akse til < 1,0 cm. All sykdom må vurderes med samme teknikk som baseline. Delvis respons (PR): Gjelder kun pasienter med minst én målbar lesjon. Større enn eller lik 30 % reduksjon under baseline av summen av passende diametre for alle målbare mållesjoner. Ingen entydig progresjon av ikke-målbar sykdom. Ingen nye lesjoner. Alle målbare lesjoner må vurderes ved å bruke de samme teknikkene som baseline.	Fra registreringsdato til progresjon eller behandlingsavbrudd, inntil 2 år og 5,5 måneder.

Sekundære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Varighet av respons (DoR) blant pasienter som oppnår en komplett respons (CR) eller delvis respons (PR) (bekreftet og ubekreftet) av RECIST 1.1. Tidsramme: Fra registreringsdato til maksimalt 2 år og 5,5 måneder eller død.	Tid fra dato for første dokumentasjon av respons (CR eller PR) til dato for første dokumentasjon av progresjon vurdert ved lokal gjennomgang eller symptomatisk forverring, eller død av enhver årsak blant pasienter som oppnår respons. Pasienter sist kjent for å være i live uten rapport om progresjon sensureres på datoen for siste sykdomsvurdering. For pasienter med manglende skanning (eller påfølgende manglende skanninger) hvis påfølgende skanning bestemmer progresjon, vil forventet dato for den første manglende skanningen bli brukt som progresjonsdato. Progresjon er definert som en eller flere av følgende: 20 % økning i summen av passende diametre av målbare mållesjoner over den minste sum observert og en absolutt økning på minst 0,5 cm; Utvetydig progresjon av ikke-målbar sykdom etter den behandlende legens mening (forklaring må gis); Utseende av ny lesjon/sted; Død på grunn av sykdom uten forutgående dokumentasjon på progresjon og uten symptomatisk forverring	Fra registreringsdato til maksimalt 2 år og 5,5 måneder eller død.
Varighet av respons (DoR) per immunrelaterte responskriterier blant pasienter som oppnår en komplett respons (CR) eller delvis respons (PR) (bekreftet og ubekreftet) av RECIST 1.1 Tidsramme: Fra registreringsdato til maksimalt 2 år og 5,5 måneder eller død	Tid fra dato for første dokumentasjon av respons (CR eller PR) til dato for første dokumentasjon av irRC-progresjon vurdert ved lokal gjennomgang eller symptomatisk forverring, eller død på grunn av en hvilken som helst årsak. Pasienter sist kjent for å være i live uten rapport om irRC-progresjon sensureres på datoen for siste sykdomsvurdering. For pasienter med en manglende skanning (eller påfølgende manglende skanninger) hvis påfølgende skanning(er) bestemmer irRC-progresjon, vil datoen for irRC-progresjon være den forventede datoen for den første manglende skanningen (som definert av sykdomsvurderingsplanen) eller datoen for den første skanningen som dokumenterer potensiell irRC-progresjon, avhengig av hva som er tidligst.	Fra registreringsdato til maksimalt 2 år og 5,5 måneder eller død
Total overlevelse (OS) blant pasienter behandlet med MEDI4736 (Durvalumab) pluss tremelimumab Tidsramme: Registreringsdato maksimalt 2 år og 5,5 måneder eller død.	Tid fra dato for delstudieregistrering til dato for død på grunn av en hvilken som helst årsak. Pasienter sist kjent for å være i live blir sensurert på datoen for siste kontakt.	Registreringsdato maksimalt 2 år og 5,5 måneder eller død.
Etterforsker-vurdert progresjonsfri overlevelse (IA-PFS) blant pasienter behandlet med MEDI4736 (Durvalumab) pluss tremelimumab. Tidsramme: Fra registreringsdato til maksimalt 2 år og 5,5 måneder eller død.	Tid fra dato for registrering av delstudie til dato for første dokumentasjon av progresjon vurdert ved lokal gjennomgang eller symptomatisk forverring, eller død på grunn av en hvilken som helst årsak. Pasienter sist kjent for å være i live uten rapport om progresjon sensureres på datoen for siste sykdomsvurdering. For pasienter med manglende skanning (eller påfølgende manglende skanninger) hvis påfølgende skanning bestemmer progresjon, ble forventet dato for den første manglende skanningen (som definert av sykdomsvurderingsplanen) brukt som dato for progresjon. Progresjon er definert som en eller flere av følgende: 20 % økning i summen av passende diametre av målbare mållesjoner over den minste sum observert og en absolutt økning på minst 0,5 cm; Utvetydig progresjon av ikke-målbar sykdom etter den behandlende legens mening (en forklaring må gis); Utseende av ny lesjon/sted; Død på grunn av sykdom uten forutgående dokumentasjon på progresjon og uten symptomatisk forverring.	Fra registreringsdato til maksimalt 2 år og 5,5 måneder eller død.
Etterforskervurdert progresjonsfri overlevelse (IA-PFS) Vurdert ved immunrelaterte responskriterier (irRC-IA-PFS) blant pasienter behandlet med MEDI4736 (Durvalumab) pluss tremelimumab Tidsramme: Registreringsdato maksimalt 2 år og 5,5 måneder eller død	Tid fra dato for registrering av delstudie til dato for første dokumentasjon av progresjon vurdert ved lokal gjennomgang eller symptomatisk forverring, eller død på grunn av en hvilken som helst årsak. Pasienter sist kjent for å være i live uten rapport om progresjon sensureres på datoen for siste sykdomsvurdering. For pasienter med manglende skanning (eller påfølgende manglende skanninger) hvis påfølgende skanning bestemmer progresjon, vil forventet dato for den første manglende skanningen (som definert av sykdomsvurderingsplanen) brukes som dato for progresjon. irRC-progresjon er definert av progresjon per RECIST 1.1 bortsett fra at progresjon bestemt av utseendet av nye lesjoner eller av en 20 % økning i summen av diametre må bekreftes ved en andre påfølgende bestemmelse av progresjon minst 28 dager fra datoen for første dokumentasjon av progresjon.	Registreringsdato maksimalt 2 år og 5,5 måneder eller død
Antall deltakere med gr 3 til 5 uønskede hendelser som er relatert til studiemedisin Tidsramme: Behandlingsvarighet og oppfølging til død eller 2 år og 5,5 måneder etter registrering	Bare uønskede hendelser som er mulig, sannsynligvis eller definitivt relatert til studiemedikamentet er rapportert. CTCAE versjon 4.0 ble brukt for rutinemessig toksisitetsrapportering og CTCAE versjon 5.0 ble brukt for rapportering av alvorlige bivirkninger (SAE).	Behandlingsvarighet og oppfølging til død eller 2 år og 5,5 måneder etter registrering

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

SWOG Cancer Research Network

Samarbeidspartnere

National Cancer Institute (NCI)

Etterforskere

Hovedetterforsker: Vassiliki Papadimitrakopoulou, SWOG Cancer Research Network

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Leighl NB, Redman MW, Rizvi N, Hirsch FR, Mack PC, Schwartz LH, Wade JL, Irvin WJ, Reddy SC, Crawford J, Bradley JD, Stinchcombe TE, Ramalingam SS, Miao J, Minichiello K, Herbst RS, Papadimitrakopoulou VA, Kelly K, Gandara DR. Phase II study of durvalumab plus tremelimumab as therapy for patients with previously treated anti-PD-1/PD-L1 resistant stage IV squamous cell lung cancer (Lung-MAP substudy S1400F, NCT03373760). J Immunother Cancer. 2021 Aug;9(8):e002973. doi: 10.1136/jitc-2021-002973.

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Faktiske)

30. november 2017

Primær fullføring (Faktiske)

18. mai 2020

Studiet fullført (Faktiske)

29. mars 2022

Datoer for studieregistrering

Først innsendt

11. desember 2017

Først innsendt som oppfylte QC-kriteriene

11. desember 2017

Først lagt ut (Faktiske)

14. desember 2017

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

9. juni 2023

Siste oppdatering sendt inn som oppfylte QC-kriteriene

7. juni 2023

Sist bekreftet

1. juni 2023

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

S1400F (Annen identifikator: CTEP)
U10CA180888 (U.S. NIH-stipend/kontrakt)
NCI-2016-01597 (Registeridentifikator: CTRP (Clinical Trial Reporting Program))

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Studerer et amerikansk FDA-regulert enhetsprodukt

Nei

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

Durvalumab og Tremelimumab i behandling av pasienter med tilbakevendende stadium IV lungekreft

En fase II-studie av MEDI4736 (Durvalumab) Pluss Tremelimumab som terapi for pasienter med tidligere behandlet anti-PD-1/PD-L1-resistent stadium IV plateepitel-lungekreft (Lung-Map Non-Match Sub-studie)

Studieoversikt

Status

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

Studietype

Registrering (Faktiske)

Fase

Kontakter og plasseringer

Studiesteder

Deltakelseskriterier

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Tar imot friske frivillige

Beskrivelse

Studieplan

Hvordan er studiet utformet?

Designdetaljer

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm

Intervensjon / Behandling

Hva måler studien?

Primære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Samarbeidspartnere og etterforskere

Sponsor

Samarbeidspartnere

Etterforskere

Publikasjoner og nyttige lenker

Generelle publikasjoner

Studierekorddatoer

Studer hoveddatoer

Studiestart (Faktiske)

Primær fullføring (Faktiske)

Studiet fullført (Faktiske)

Datoer for studieregistrering

Først innsendt

Først innsendt som oppfylte QC-kriteriene

Først lagt ut (Faktiske)

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

Siste oppdatering sendt inn som oppfylte QC-kriteriene

Sist bekreftet

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Studerer et amerikansk FDA-regulert enhetsprodukt