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Effects of Different High-Intensity Interval Training Protocols on Physiological and Skeletal Muscle Adaptations in Healthy Young Men

4 listopada 2026 zaktualizowane przez: Gdansk University of Physical Education and Sport

This study investigated the effects of different high-intensity interval training protocols on physical fitness and physiological adaptations in healthy young men.

Participants underwent a two-week exercise training program consisting of six sessions performed three times per week. Four training protocols were investigated, differing in exercise intensity, duration of exercise bouts, and recovery periods.

The primary outcome was the change in maximal oxygen uptake (VO2max), an indicator of aerobic fitness. Additional assessments included cognitive performance, measured using tests of attention, processing speed, and inhibitory control, as well as selected physiological and skeletal muscle adaptations.

The study aimed to improve understanding of how different high-intensity interval training protocols influence aerobic fitness and other physiological responses over a short training period.

Przegląd badań

Szczegółowy opis

High-intensity interval training (HIIT) and sprint interval training (SIT) are exercise strategies characterized by repeated bouts of vigorous or maximal exercise interspersed with recovery periods. These training approaches may induce physiological adaptations within relatively short intervention periods. However, the effects of different combinations of exercise duration, intensity, and recovery time on aerobic fitness, cognitive performance, and skeletal muscle adaptations require further investigation.

This interventional study examined physiological responses to four cycling-based high-intensity training protocols in healthy young men. Participants completed six training sessions over two weeks, with three sessions performed each week.

The investigated protocols included:

SIT10:1: Repeated 10-second maximal cycling sprints separated by 60-second recovery periods.

SIT10:4: Repeated 10-second maximal cycling sprints separated by 240-second recovery periods.

HIIT90:180: Six 90-second cycling intervals performed at 80% of maximal aerobic power, separated by 180-second passive recovery periods.

Wingate-SIT: Repeated 30-second all-out cycling sprints using a Wingate-based protocol.

The primary outcome was the change in maximal oxygen uptake (VO2max), assessed using incremental exercise testing before and after the intervention. Additional assessments included cognitive performance using the Stroop Color-Word Test, Trail Making Test, and Digit Span Test, as well as selected measures of exercise performance and skeletal muscle metabolic adaptations.

Skeletal muscle biopsies were collected from subsets of participants before and after training to investigate exercise-induced adaptations in muscle tissue. Stored biopsy samples were subsequently used for exploratory proteomic analyses.

The study was designed to characterize short-term physiological and skeletal muscle responses to different high-intensity interval exercise protocols.

Typ studiów

Interwencyjne

Zapisy (Rzeczywisty)

50

Faza

  • Nie dotyczy

Kontakty i lokalizacje

Ta sekcja zawiera dane kontaktowe osób prowadzących badanie oraz informacje o tym, gdzie badanie jest przeprowadzane.

Lokalizacje studiów

    • Pomeranian
      • Gdansk, Pomeranian, Polska, 80-336
        • Gdansk University of Physical Education and Sport

Kryteria uczestnictwa

Badacze szukają osób, które pasują do określonego opisu, zwanego kryteriami kwalifikacyjnymi. Niektóre przykłady tych kryteriów to ogólny stan zdrowia danej osoby lub wcześniejsze leczenie.

Kryteria kwalifikacji

Wiek uprawniający do nauki

18 lat do 35 lat (Dorosły)

Akceptuje zdrowych ochotników

Tak

Płeć kwalifikująca się do nauki

Męski

Opis

Inclusion Criteria:

Healthy adult males. Physically active individuals. Ability to perform high-intensity cycling exercise. Willingness to participate in the two-week training intervention and complete the required assessments.

Provision of written informed consent.

Exclusion Criteria:

Known cardiovascular, respiratory, metabolic, or neurological disorders that could affect exercise performance or participant safety.

Musculoskeletal injuries or conditions preventing participation in high-intensity cycling exercise.

Medical contraindications to maximal exercise testing or sprint interval training.

Plan studiów

Ta sekcja zawiera szczegółowe informacje na temat planu badania, w tym sposób zaprojektowania badania i jego pomiary.

Jak projektuje się badanie?

Szczegóły projektu

  • Główny cel: Podstawowa nauka
  • Przydział: Nielosowe
  • Model interwencyjny: Przydział równoległy
  • Maskowanie: Brak (otwarta etykieta)

Broń i interwencje

Grupa uczestników / Arm
Interwencja / Leczenie
Eksperymentalny: SIT10:1 - Short-Recovery Sprint Interval Training

Participants completed a two-week cycling sprint interval training program comprising six sessions (three sessions per week). The protocol involved repeated 10-second maximal cycling sprints separated by 60-second recovery intervals.

A two-week cycling sprint interval training intervention consisting of six sessions performed three times per week. Participants performed repeated 10-second maximal cycling sprints interspersed with 60-second recovery intervals.

Eksperymentalny: SIT10:4 - Long-Recovery Sprint Interval Training

Participants completed a two-week cycling sprint interval training program comprising six sessions (three sessions per week). The protocol involved repeated 10-second maximal cycling sprints separated by 240-second recovery intervals.

A two-week cycling sprint interval training intervention consisting of six sessions performed three times per week. Participants performed repeated 10-second maximal cycling sprints interspersed with 240-second recovery intervals.

Eksperymentalny: HIIT90:180 - High-Intensity Interval Training

Participants completed a two-week high-intensity interval cycling program consisting of six supervised training sessions (three sessions per week). Each session included six 90-second cycling bouts performed at 80% of maximal aerobic power, separated by 180-second passive recovery intervals. Exercise cadence was maintained at approximately 60 revolutions per minute.

A two-week cycling high-intensity interval training intervention comprising six supervised sessions performed three times per week. Each session consisted of six 90-second exercise bouts at 80% of maximal aerobic power, separated by 180-second passive recovery intervals. Cycling cadence was approximately 60 revolutions per minute.

Eksperymentalny: Wingate-SIT - Wingate-Based Sprint Interval Training

Participants completed a two-week sprint interval training program comprising six cycling sessions (three sessions per week). The intervention consisted of repeated 30-second all-out cycling sprints performed using a Wingate-based protocol, with recovery periods between successive efforts.

A two-week cycling sprint interval training intervention comprising six sessions performed three times per week. Participants performed repeated 30-second all-out cycling sprints using a Wingate-based protocol, with recovery intervals between successive sprints.

Co mierzy badanie?

Podstawowe miary wyniku

Miara wyniku
Opis środka
Ramy czasowe
Change in Maximal Oxygen Uptake (VO2max)
Ramy czasowe: Baseline and after the 2-week training intervention

Change in maximal oxygen uptake (VO2max), expressed in mL/kg/min, assessed using an incremental exercise test before and after the two-week training intervention.

Baseline and after the 2-week training intervention

Miary wyników drugorzędnych

Miara wyniku
Opis środka
Ramy czasowe
Change in Cognitive Performance
Ramy czasowe: Baseline and after the 2-week training intervention

Changes in cognitive performance assessed using the Stroop Color-Word Test (inhibitory control), Trail Making Test (processing speed and executive function), and Digit Span Test (working memory), before and after the two-week training intervention.

Baseline and after the 2-week training intervention
Change in Skeletal Muscle Oxidative Enzyme Activity
Ramy czasowe: Baseline and after the 2-week training intervention

Changes in skeletal muscle oxidative enzyme activity assessed in biopsy samples collected before and after the two-week training intervention. Muscle biopsies were performed in a subset of participants who provided additional informed consent for the procedure.

Baseline and after the 2-week training intervention

Współpracownicy i badacze

Tutaj znajdziesz osoby i organizacje zaangażowane w to badanie.

Daty zapisu na studia

Daty te śledzą postęp w przesyłaniu rekordów badań i podsumowań wyników do ClinicalTrials.gov. Zapisy badań i zgłoszone wyniki są przeglądane przez National Library of Medicine (NLM), aby upewnić się, że spełniają określone standardy kontroli jakości, zanim zostaną opublikowane na publicznej stronie internetowej.

Główne daty studiów

Rozpoczęcie studiów (Rzeczywisty)

10 lutego 2013

Zakończenie podstawowe (Rzeczywisty)

17 kwietnia 2018

Ukończenie studiów (Rzeczywisty)

30 grudnia 2018

Daty rejestracji na studia

Pierwszy przesłany

4 listopada 2026

Pierwszy przesłany, który spełnia kryteria kontroli jakości

4 listopada 2026

Pierwszy wysłany (Rzeczywisty)

9 listopada 2026

Aktualizacje rekordów badań

Ostatnia wysłana aktualizacja (Rzeczywisty)

9 listopada 2026

Ostatnia przesłana aktualizacja, która spełniała kryteria kontroli jakości

4 listopada 2026

Ostatnia weryfikacja

1 listopada 2026

Więcej informacji

Terminy związane z tym badaniem

Plan dla danych uczestnika indywidualnego (IPD)

Planujesz udostępniać dane poszczególnych uczestników (IPD)?

NIE

Opis planu IPD

Individual participant data will not be made publicly available due to participant confidentiality considerations and the absence of a data-sharing plan in the original study protocol.

Informacje o lekach i urządzeniach, dokumenty badawcze

Bada produkt leczniczy regulowany przez amerykańską FDA

Nie

Bada produkt urządzenia regulowany przez amerykańską FDA

Nie

Te informacje zostały pobrane bezpośrednio ze strony internetowej clinicaltrials.gov bez żadnych zmian. Jeśli chcesz zmienić, usunąć lub zaktualizować dane swojego badania, skontaktuj się z register@clinicaltrials.gov. Gdy tylko zmiana zostanie wprowadzona na stronie clinicaltrials.gov, zostanie ona automatycznie zaktualizowana również na naszej stronie internetowej .

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