此页面是自动翻译的，不保证翻译的准确性。请参阅英文版对于源文本。

Connect to Protect Partnerships for Youth Prevention Interventions: Phase II

2017年2月27日更新者：University of North Carolina, Chapel Hill

Connect to Protect (C2P) Partnerships for Youth Prevention Interventions: Phase II

This is Phase II of a three stage project whose overall goals are to develop viable community-based HIV prevention interventions and to form and maintain the necessary community collaborations to support such Adolescent Trials Network (ATN) research activities.

This phase will describe specific locations within high-risk areas where youth, ages 12-24, spend time. HIV risk behaviors, social networking patterns and HIV prevalence among youth at these venues will be assessed by administering anonymous computerized interviews to eligible and willing youth. This information will be shared with community partners during scheduled working group meetings.

研究概览

地位

完全的

条件

爱滋病毒感染

详细说明

During this phase, each ATN site will gather additional information within high-risk areas and solicit community partner input to ultimately pinpoint the specific locations where at-risk youths, ages 12-24, may be recruited for interventions. This will be done by the following methods:

Venues will be identified by HIV+ youth at the ATN site by participation in an anonymous computerized interview. Site staff will then perform brief venue interviews (BVIs) at selected venues to assess the potential yield of youths 12-24 years old. Community partners will also provide the site staff with information on known high-risk venues. High-risk venues will further be identified by the results of anonymous computerized interviews and HIV assays obtained from eligible and willing youth participants at the venues. The interviews will gather information on HIV risk behaviors, social networking patterns and HIV prevalence among youths at these venues. This information will be shared with community partners during scheduled working group meetings.

研究类型

观察性的

注册 (实际的)

16706

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习地点

波多黎各
- - San Juan、波多黎各、00936
    - University Pediatric Hospital
美国
- California
  - Los Angeles、California、美国、90054
    - Childrens Hospital of Los Angeles
  - San Diego、California、美国、92103
    - UCSD Mother, Child & Adolescent HIV Program
  - San Francisco、California、美国、94143
    - Univ of Califormia at San Francisco
- District of Columbia
  - Washington、District of Columbia、美国、20010
    - Children's Hospital National Medical Center
- Florida
  - Ft. Lauderdale、Florida、美国、33301
    - Children's Diag. and Treatment Center
  - Miami、Florida、美国、33101
    - University of Miami
  - Tampa、Florida、美国、33606
    - USF Peds Div. of Infectious Disease
- Illinois
  - Chicago、Illinois、美国、60612
    - Stroger Hospital of Cook County
- Louisiana
  - New Orleans、Louisiana、美国、70112
    - Tulane Medical Center
- Maryland
  - Baltimore、Maryland、美国、21201
    - University of Maryland
- Massachusetts
  - Boston、Massachusetts、美国、02115
    - Childrens' Hospital of Boston
- New York
  - Bronx、New York、美国、10467
    - Montefiore Medical Center, Adolescent AIDS Program
  - New York、New York、美国、10128
    - Mount Sinai Medical Center
- Pennsylvania
  - Philadelphia、Pennsylvania、美国、19104
    - Children's Hopsital of Philadelphia

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

12年至 24年 (孩子、成人)

接受健康志愿者

是的

有资格学习的性别

全部

取样方法

非概率样本

研究人群

HIV infected youth, ages 12 through 24 years old, in treatment/care at each of the 15 ATN sites will be interviewed using ACASI technology to reveal possible venues where youth at high risk for acquiring the HIV may be found. Individuals approached at 3-5 of these identified venues who appear to be 12 through 24 years will be offered a brief venue interview. Anonymous HIV serosurvey (ACASI and HIV-Ab assay) will be administered to 20-30 young women at 2-3 identified high-risk venues, and 20-30 young men at 2-3 identified high-risk venues, who provide verbal confirmation of being 12 through 24 years old, and whose HIV status is unknown to the site staff.

描述

Inclusion Criteria:

Index Subjects:

Documented HIV-infection
Acquisition of HIV after age 9 years
Verbal confirmation of 12-24 years of age
Verbal report of having engaged in sexual activity (vaginal, anal and/or oral sex) within the past 12 months
Ability to understand and willingness to provide informed consent/assent

BVI subjects:

Youths who appear to be 12-24 years old

HIV Serosurvey subjects at the venues:

Verbal confirmation of 12-24 years of age
Verbal report of having engaged in sexual activity (vaginal, anal and/or oral sex) within the past 12 months
Ability to understand and willingness to provide informed consent/assent

Exclusion Criteria:

Visibly distraught and/or emotionally unstable (i.e. depressive mood, exhibiting manic, suicidal or violent behavior, etc.)
Visibly intoxicated or under the influence of psychoactive agents
Clinically presents as acutely ill

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

团体/队列数

队列和干预

团体/队列
HIV Infected Youth in Treatment/Care HIV infected youth in treatment/care will be interviewed using Audio Computer-Assisted Self-Administered Interview ACASI technology to reveal possible venues where youth at high risk for acquiring the disease may be found (N = 20-30 individuals per ATN site).
BVI Individuals Additional data will be gathered on potential recruitment venues by administering a brief venue interview (BVI) to individuals who appear to be between 12 and 24 years old (N = unlimited individuals during 3-5 assessment periods per venue each lasting 5 hours).
HIV Serosurvey Individuals HIV Serosurvey Individuals Anonymous structured interview using ACASI technology and an anonymous HIV antibody assay will be administered to 20-30 young women at 2-3 targeted locations and 20-30 young men at 2-3 targeted locations whose HIV status is unknown (N = 160-360 individuals per ATN site)..

研究衡量的是什么？

主要结果指标

结果测量	措施说明	大体时间
Ascertain specific community venues where at-risk youth can be recruited for interventions within the high-risk areas identified in the first Phase of the study 大体时间：One time assessment at 10 months	The outcome measure will be assessed using results from: (a) Phase I mapping; (b) Phase II interviews with HIV-infected youth; and (c) Phase II Brief Venue Interviews (BVIs). Input from community partners and ethnographic procedures will add critical information.	One time assessment at 10 months
Describe HIV risk behaviors of adolescents and young adults recruited from targeted venues 大体时间：One time assessment at 10 months	The outcome measure will be assessed by conducting HIV serosurveys at each venue identified with youth whose HIV status is unknown.	One time assessment at 10 months
Describe social networks of adolescents and young adults recruited from targeted venues 大体时间：One time assessment at 10 months	The outcome measure will be assessed by conducting HIV serosurveys at each venue identified with youth whose HIV status is unknown.	One time assessment at 10 months
Describe HIV seroprevalence of adolescents and young adults recruited from targeted venues 大体时间：One time assessment at 10 months	The outcome measure will be assessed by conducting HIV serosurveys at each venue identified with youth whose HIV status is unknown.	One time assessment at 10 months
Assess the characteristics of the community-researcher partnerships 大体时间：One time assessment at 10 months	The outcome measure will be assessed by conducting interviews with C2P staff and their community partners. Questionnaires will be completed by both parties and detailed documentation kept.	One time assessment at 10 months
Assess quality of the community-researcher partnerships 大体时间：One time assessment at 10 months	The outcome measure will be assessed by conducting interviews with C2P staff and their community partners. Questionnaires will be completed by both parties and detailed documentation kept.	One time assessment at 10 months
Assess outcomes of the community-researcher partnerships 大体时间：One time assessment at 10 months	The outcome measure will be assessed by conducting interviews with C2P staff and their community partners. Questionnaires will be completed by both parties and detailed documentation kept.	One time assessment at 10 months

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

University of North Carolina, Chapel Hill

合作者

National Institute on Drug Abuse (NIDA)

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

National Institute of Mental Health (NIMH)

调查人员

首席研究员：Donna Futterman, MD、Montefiore Medical Center
首席研究员：Sue Ellen Abdalian, MD、Tulane Medical Center
学习椅：Jonathan Ellen, MD、Johns Hopkins Medical Center
首席研究员：Ligia Peralta, MD、Division of Adolescent & Young Adult Medicine University of MD, Medical School
首席研究员：Marvin Belzer, MD、Childrens Hosp of Los Angeles, Division of Adolescent Medicine
首席研究员：Bret Rudy, MD、Children's Hospital of Philadelphia
首席研究员：Larry D'Angelo, MD、Children's National Research Institute
首席研究员：Cathryn Samples, MD、Boston Children's Hospital
首席研究员：Lisa Henry-Reid, MD、John H. Stroger Jr. Hospital and the CORE Center
首席研究员：Ana Puga, MD、Children's Diag. and Treatment Ctr of Ft. Lauderdale, FL
首席研究员：Lawrence Friedman, MD、University of Miami, School of Medicine, Div of Adolescent Medicine
首席研究员：Patricia Emmanuel, MD、University of South Florida, Peds Div of Infectious Disease
首席研究员：Linda Levin, MD、Mount Sinai Adolescent Health Center
首席研究员：Irma Febo, MD、University of Puerto Rico Medical Sciences Campus
首席研究员：Stephen A Spector, MD、UCSD Mother, Child, & Adolescent HIV Program
首席研究员：Rolando M Viani, MD、UCSD Mother, Child, & Adolescent HIV Program
首席研究员：Barbara Moscicki, MD、UCSF, Division of Adoles. Med
首席研究员：Coco Auerswald, MD、UCSF, Division of Adoles. Med

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

有用的网址

Website for the Adolescent Trials Network for HIV/AIDS Interventions

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2003年9月1日

初级完成 (实际的)

2010年10月1日

研究完成 (实际的)

2010年10月1日

研究注册日期

首次提交

2005年2月15日

首先提交符合 QC 标准的