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Impulsivity in Pathological Gambling

2013年6月3日 更新者：Timothy Fong MD、University of California, Los Angeles

Impulsivity in Pathological Gambling: A Cross Sectional Analysis on Tests of Impulsivity Between Pathological Gamblers and a Non-pathological Control Group.

The purpose of the this study is to compare pathological gamblers versus non-pathological gamblers using tests that measure different components of impulsivity. We aim to invite a total of 120 individuals to participate in this study.

Impulsivity has been described as the cognitive inability to delay gratification, a failure to inhibit behavioral action or acting without forethought about consequences. Impulsivity has also been seen as a personality trait characterized by risk-taking or sensation seeking behavior. Pathological gamblers demonstrate aspects of impulsivity; they act without thinking, have difficult inhibiting urges to gamble and desire immediate gratification. The goal of this project is to clarify which components of impulsivity are associated with pathological gambling. Non-treatment seeking, pathological gamblers and controls will be recruited from the community and local casinos. Each participant will be administered a battery of tests that represent different operational definitions of impulsivity.

研究概览

地位

完全的

条件

详细说明

Personality traits of impulsivity will be measured with the Barrett Impulsiveness Scale and the NEO Personality Inventory-Revised. Behavioral components of impulsivity will be tested through delay and probability discounting tasks. Finally, measures of frontotemporal functioning are also included in a neuropsychology and neurocognitive battery. Recent studies have shown that these areas of the brain function differently in pathological gamblers; thus, the following neuropsychology/neurocognitive tests have been included: Attention/Information Processing Speed (via Simple Reaction Time Task and Continuous Performance Task), Episodic Memory (via Hopkins Verbal Learning Test-Revised and Brief Visuospatial Memory Test), Executive/Frontal Lobe Measures (via Wechsler Memory Scale-III, Choice Reaction Time Task, Working Memory Task (N-back), Probabilistic Reversal Learning Task, and Stop-Signal Task). Between group comparisons on this battery of impulsivity tests will be made to clarify which components of impulsivity are associated with pathological gambling. Secondly, within-group analyses will be performed to correlate impulsivity to gambling severity. Lastly, an exploratory analysis of subtyping pathological gamblers by performances on tasks of impulsivity and types of gambling will be conducted.

研究类型

观察性的

注册 (实际的)

120

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习地点

  • 美国
    • California
      • Los Angeles、California、美国、90095
        • UCLA Neuropsychiatric Institute

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 及以上 (成人、年长者)

接受健康志愿者

是的

有资格学习的性别

全部

取样方法

非概率样本

研究人群

Community Sample

描述

Inclusion Criteria:

Inclusion Criteria for Pathological Gamblers:

  • 18 years or older
  • Be able to speak, read and write in English
  • Current diagnosis of pathological gambling (using DSM-IV criteria)
  • South Oaks Gambling Screen (SOGS) score of 5 or above during screening
  • Recent gambling activity -- at least once within one week prior to enrollment.
  • Voluntarily given informed consent and signed the informed consent document.
  • Not currently seeking treatment for gambling

Inclusion Criteria For Control Participants:

  • 18 years or older
  • Be able to speak, read and write in English
  • South Oaks Gambling Screen (SOGS) score of 5 or less during screening
  • Voluntarily given informed consent and signed the informed consent document
  • Does not meet diagnosis of pathological gambling by DSM-IV criteria
  • Not currently seeking treatment for gambling

Exclusion Criteria:

Exclusion Criteria for all participants:

  • Current treatment for pathological gambling, excluding involvement with Gamblers Anonymous
  • Ongoing medication for any psychiatric disorders, including anti-psychotics, antidepressants, mood stabilizers, anxiolytics or sedative/hypnotics.
  • Dependence by DSM-IV criteria on any psychoactive substance, excluding caffeine or nicotine
  • Presence of clinically unstable medical disorders that could harm the subject if not treated immediately.
  • Presence of any neurological or psychiatric disorders (as assessed by the SCID or MINI and BDI-II) that would require immediate treatment.
  • Test positive urine toxicology for illicit drugs prior to enrollment
  • Hamilton Depression Scale score of >17

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

队列和干预

团体/队列
1
Pathological Gamblers
2
Non-Pathological Gamblers

研究衡量的是什么？

主要结果指标

结果测量
大体时间
Barratt Impusivity Scale
大体时间：12 months
12 months

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

University of California, Los Angeles

合作者

National Institute on Drug Abuse (NIDA)

调查人员

  • 首席研究员：Timothy W. Fong, M.D.、UCLA Gambling Studies Program

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

有用的网址

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2007年3月1日

初级完成 (实际的)

2009年8月1日

研究完成 (实际的)

2009年8月1日

研究注册日期

首次提交

2007年12月20日

首先提交符合 QC 标准的

2007年12月20日

首次发布 (估计)

2007年12月24日

研究记录更新

最后更新发布 (估计)

2013年6月4日

上次提交的符合 QC 标准的更新

2013年6月3日

最后验证

2013年6月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • PA-00-004
  • K23DA019522 (美国 NIH 拨款/合同)

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

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